Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 4.1.2.45 - trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

for references in articles please use BRENDA:EC4.1.2.45

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

This enzyme is involved in naphthalene degradation. The enzyme catalyses a retro-aldol reaction in vitro, and it accepts a broad range of aldehydes and 4-substituted 2-oxobut-3-enoates as substrates .

The enzyme appears in viruses and cellular organisms

Synonyms
trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, 2'-hydroxybenzalpyruvate aldolase, thbp-ha, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = salicylaldehyde + pyruvate
show the reaction diagram
-
-
-
-
Highest Expressing Human Cell Lines
Cell Line Links Gene Links