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Information on EC 4.1.2.14 - 2-dehydro-3-deoxy-phosphogluconate aldolase

for references in articles please use BRENDA:EC4.1.2.14

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IUBMB Comments

The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D-galactonate. cf. EC 4.1.2.55, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase . Also acts on 2-oxobutanoate .

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
2-keto-3-deoxy-6-phosphogluconate aldolase, kdpg aldolase, kdpga, phospho-2-keto-3-deoxygluconate aldolase, kdpg-aldolase, 2-dehydro-3-deoxy-phosphogluconate aldolase, kd(p)g aldolase, 6-phospho-2-keto-3-deoxygluconate aldolase, 2-keto-3-deoxygluconate-6-phosphate aldolase, 2-dehydro-3-deoxyphosphogluconate aldolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-dehydro-3-deoxy-6-phospho-D-gluconate = pyruvate + D-glyceraldehyde 3-phosphate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
3,6-anhydro-alpha-L-galactopyranose degradation, 4-deoxy-L-threo-hex-4-enopyranuronate degradation, D-fructuronate degradation, D-galacturonate degradation I, D-glucosaminate degradation, Entner-Doudoroff pathway III (semi-phosphorylative), Entner-Doudoroff shunt