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Information on EC 4.1.1.87 - malonyl-S-ACP decarboxylase

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.87 malonyl-S-ACP decarboxylase
IUBMB Comments
This enzyme comprises the beta and gamma subunits of EC 4.1.1.88, biotin-independent malonate decarboxylase but is not present in EC 7.2.4.4, biotin-dependent malonate decarboxylase. It follows on from EC 2.3.1.187, acetyl-S-ACP:malonate ACP transferase, and results in the regeneration of the acetylated form of the acyl-carrier-protein subunit of malonate decarboxylase . The carboxy group is lost with retention of configuration .
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The enzyme appears in viruses and cellular organisms
Synonyms
malonyl-S-acyl-carrier protein decarboxylase, MdcD,E, MdcD/MdcE, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a malonyl-[acyl-carrier protein] + H+ = an acetyl-[acyl-carrier protein] + CO2
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PATHWAY SOURCE
PATHWAYS
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