Reference on EC 4.1.1.84 - D-dopachrome decarboxylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Odh, G.; Hindemith, A.; Rosengren, A-M.; Rosengren, E.; Rorsman, H.
Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindole
Biochem. Biophys. Res. Commun.
197
619-624
1993
Rattus norvegicus (P80254)
Nishihira, J.; Fujinaga, M.; Kuriyama, T.; Suzuki, M.; Sugimoto, H.; Nakagawa, A.; Tanaka, I.; Sakai, M.
Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation
Biochem. Biophys. Res. Commun.
243
538-544
1998
Homo sapiens (P30046)
Yoshida, H.; Nishihira, J.; Suzuki, M.; Hikichi, K.
NMR characterization of physicochemical properties of rat D-dopachrome tautomerase
Biochem. Mol. Biol. Int.
42
891-899
1997
Rattus norvegicus (P80254)
Sugimoto, H.; Taniguchi, M.; Nakagawa, A.; Tanaka, I.; Suzuki, M.; Nishihira, J.
Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution
Biochemistry
38
3268-3279
1999
Homo sapiens (P30046)
Kuriyama T.;Fujinaga M.;Koda T.;Nishihira J.
Cloning of the mouse gene for D-dopachrome tautomerase.
Biochim. Biophys. Acta
1388
506-512
1998
Mus musculus (O35215)
Bjoerk, P.; Aman, P.; Hindemith, A.; Odh, G.; Jacobsson, L.; Rosengren, E.; Rorsman, H.
A new enzyme activity in human blood cells and isolation of the responsible protein (D-dopachrome tautomerase) from erythrocytes
Eur. J. Haematol.
57
254-256
1996
Homo sapiens, Bos taurus
Sonesson, B.; Rosengren, E.; Hansson, A.S.; Hansson, C.
UVB-induced inflammation gives increased d-dopachrome tautomerase activity in blister fluid which correlates with macrophage migration inhibitory factor
Exp. Dermatol.
12
278-282
2003
Homo sapiens (P30046)
Sugimoto, H.; Taniguchi, M.; Nakagawa, A.; Tanaka, I.; Suzuki, M.; Nishihira, J.
Crystallization and preliminary x-ray analysis of human D-dopachrome tautomerase
J. Struct. Biol.
120
105-108
1997
Homo sapiens (P30046)
Rosengren, E.; Thelin, S.; Aman, P.; Hansson, C.; Jacobsson, L.; Rorsman, H.
The protein catalysing the conversion of D-dopachrome to 5,6-dihydroxyindole is a phenylpyruvate tautomerase (EC 5.3.2.1)
Melanoma Res.
7
517-518
1997
Rattus norvegicus
Coleman, A.M.; Rendon, B.E.; Zhao, M.; Qian, M.W.; Bucala, R.; Xin, D.; Mitchell, R.A.
Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase
J. Immunol.
181
2330-2337
2008
Homo sapiens (P30046), Mus musculus (O35215)
Hiyoshi, M.; Konishi, H.; Uemura, H.; Matsuzaki, H.; Tsukamoto, H.; Sugimoto, R.; Takeda, H.; Dakeshita, S.; Kitayama, A.; Takami, H.; Sawachika, F.; Kido, H.; Arisawa, K.
D-Dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride
Toxicology
255
6-14
2009
Rattus norvegicus
Garai, J.; Lorand, T.
Macrophage migration inhibitory factor (MIF) tautomerase inhibitors as potential novel anti-inflammatory agents: current developments
Curr. Med. Chem.
16
1091-1114
2009
Homo sapiens
Li, H.; He, B.; Zhang, X.; Hao, H.; Yang, T.; Sun, C.; Song, H.; Wang, Y.; Zhou, Y.; Zhu, Z.; Hu, Y.; Wang, Y.
D-dopachrome tautomerase drives astroglial inflammation via NF-kappaB signaling following spinal cord injury
Cell Biosci.
12
128
2022
Rattus norvegicus (P80254)
Song, S.; Liu, B.; Habibie, H.; van den Bor, J.; Smit, M.J.; Gosens, R.; Wu, X.; Brandsma, C.A.; Cool, R.H.; Haisma, H.J.; Poelarends, G.J.; Melgert, B.N.
D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling
EBioMedicine
68
103412
2021
Homo sapiens (P30046)
Yoshihisa, Y.; Rehman, M.U.; Andoh, T.; Tabuchi, Y.; Makino, T.; Shimizu, T.
Overexpression of D-dopachrome tautomerase increases ultraviolet B irradiation-induced skin tumorigenesis in mice
FASEB J.
35
e21671
2021
Mus musculus (O35215)
Li, L.; Jing, L.; Wang, J.; Xu, W.; Gong, X.; Zhao, Y.; Ma, Y.; Yao, X.; Sun, X.
Autophagic flux is essential for the downregulation of D-dopachrome tautomerase by atractylenolide I to ameliorate intestinal adenoma formation
J. Cell Commun. Signal.
12
689-698
2018
Homo sapiens (P30046), Mus musculus (O35215)
Xiao, Z.; Osipyan, A.; Song, S.; Chen, D.; Schut, R.A.; van Merkerk, R.; van der Wouden, P.E.; Cool, R.H.; Quax, W.J.; Melgert, B.N.; Poelarends, G.J.; Dekker, F.J.
Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione derivative inhibits D-dopachrome tautomerase activity and suppresses the proliferation of non-small cell lung cancer cells
J. Med. Chem.
65
2059-2077
2022
Homo sapiens (P30046)
Ji, H.; Zhang, Y.; Chen, C.; Li, H.; He, B.; Yang, T.; Sun, C.; Hao, H.; Zhang, X.; Wang, Y.; Zhou, Y.; Zhu, Z.; Hu, Y.; Li, A.; Guo, A.; Wang, Y.
D-dopachrome tautomerase activates COX2/PGE2 pathway of astrocytes to mediate inflammation following spinal cord injury
J. Neuroinflammation
18
130
2021
Rattus norvegicus (P80254)
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