Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 4.1.1.84 - D-dopachrome decarboxylase and Organism(s) Mus musculus and UniProt Accession O35215

for references in articles please use BRENDA:EC4.1.1.84
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.84 D-dopachrome decarboxylase
IUBMB Comments
This enzyme is specific for D-dopachrome as substrate and belongs to the MIF (macrophage migration inhibitory factor) family of proteins. L-Dopachrome, L- or D-alpha-methyldopachrome and dopaminochrome do not act as substrates (see also EC 5.3.3.12, L-dopachrome isomerase)
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Mus musculus
UNIPROT: O35215
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
The taxonomic range for the selected organisms is: Mus musculus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
d-dopachrome decarboxylase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D-dopachrome tautomerase
-
SYSTEMATIC NAME
IUBMB Comments
D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming)
This enzyme is specific for D-dopachrome as substrate and belongs to the MIF (macrophage migration inhibitory factor) family of proteins. L-Dopachrome, L- or D-alpha-methyldopachrome and dopaminochrome do not act as substrates (see also EC 5.3.3.12, L-dopachrome isomerase)
CAS REGISTRY NUMBER
COMMENTARY hide
184111-06-6
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
murine embryonic fibroblast
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DOPD_MOUSE
118
0
13077
Swiss-Prot
other Location (Reliability: 2)
PDB
SCOP
CATH
UNIPROT
ORGANISM
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kuriyama T.;Fujinaga M.;Koda T.;Nishihira J.
Cloning of the mouse gene for D-dopachrome tautomerase.
Biochim. Biophys. Acta
1388
506-512
1998
Mus musculus (O35215)
Manually annotated by BRENDA team
Coleman, A.M.; Rendon, B.E.; Zhao, M.; Qian, M.W.; Bucala, R.; Xin, D.; Mitchell, R.A.
Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase
J. Immunol.
181
2330-2337
2008
Mus musculus (O35215), Homo sapiens (P30046)
Manually annotated by BRENDA team