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Information on EC 4.1.1.83 - 4-hydroxyphenylacetate decarboxylase

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.83 4-hydroxyphenylacetate decarboxylase
IUBMB Comments
The enzyme, from the strict anaerobe Clostridium difficile, can also use (3,4-dihydroxyphenyl)acetate as a substrate, yielding 4-methylcatechol as a product. The enzyme is a glycyl radical enzyme.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
4-HPAD, 4-Hpd, 4-hydroxyphenylacetate decarboxylase, 4Hpad, 4Hpad-AE, CSD, HPA decarboxylase, HPD, p-Hpd, p-hydroxyphenylacetate decarboxylase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(4-hydroxyphenyl)acetate + H+ = 4-methylphenol + CO2
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