Information on EC 4.1.1.56 - 3-oxolaurate decarboxylase

for references in articles please use BRENDA:EC4.1.1.56
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The enzyme appears in viruses and cellular organisms

top print hide
EC NUMBER
COMMENTARY hide
4.1.1.56
-
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RECOMMENDED NAME
GeneOntology No.
3-oxolaurate decarboxylase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-oxododecanoate = 2-undecanone + CO2
show the reaction diagram
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-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
decarboxylation
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-
-
-
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
2-methylketone biosynthesis
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-
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SYSTEMATIC NAME
IUBMB Comments
3-oxododecanoate carboxy-lyase (2-undecanone-forming)
Also decarboxylates other C14 to C16 oxo acids.
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top print hide
CAS REGISTRY NUMBER
COMMENTARY hide
37290-49-6
-
top print hide
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-Oxododecanoate
2-Undecanone + CO2
show the reaction diagram
3-Oxododecanoate
?
show the reaction diagram
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
3-Oxododecanoate
?
show the reaction diagram
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
-
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
top print hide
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 10
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pH 5.0: about 25% of maximal activity, pH 10.0: about 50% of maximal activity
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
resting and germinating
Manually annotated by BRENDA team
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
top print hide
pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1
-
15 min, 21°C, about 40% loss of activity
4718
3
-
15 min, 21°C, about 20% loss of activity
4718
5 - 7
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15 min, 21°C, stable
4718
8
-
15 min, 21°C, about 5% loss of activity
4718
9
-
15 min, 21°C, about 20% loss of activity
4718
10
-
15 min, 21°C, about 50% loss of activity
4718
11
-
15 min, 21°C, complete loss of activity
4718
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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
half-life: 31 min
35
-
half-life: 6 min
40
-
half-life: 2.5 min
100
-
about 10% loss of activity after 30 min, about 25% loss of activity after 60 min, about 50% loss of activity after 90 min, enzyme in crude extract
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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
dialysis against water, at 14°C, 30% loss of activity
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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, stable for 2 months
-
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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
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LINKS TO OTHER DATABASES (specific for EC-Number 4.1.1.56)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)