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Information on EC 4.1.1.39 - ribulose-bisphosphate carboxylase and Organism(s) Galdieria sulphuraria and UniProt Accession P23755
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4.1.1.39 ribulose-bisphosphate carboxylaseIUBMB Comments
Will utilize O2 instead of CO2, forming 3-phospho-D-glycerate and 2-phosphoglycolate.
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Word Map
- 4.1.1.39
- co2
- chloroplast
- chlorophyll
-
stomatal
- plastid
- mesophyll
- activase
- photosystems
- spinach
- seedling
- dioxide
- thylakoids
- phosphoenolpyruvate
- wheat
-
photorespiration
-
atmospheric
- maize
-
acclimation
- chlamydomonas
- cyanobacteria
- drought
- reinhardtii
-
autotroph
-
photochemical
- anhydrase
-
photorespiratory
-
calvin
-
climate
-
light-harvesting
-
transpiration
-
nuclear-encoded
- rubrum
- aestivum
- triticum
- rhodospirillum
- 3-phosphoglycerate
-
canopy
- synechococcus
- phosphoribulokinase
-
photoautotrophic
-
photochemistry
- analysis
-
crassulacean
- molecular biology
- lhcii
- biotechnology
-
photoinhibition
-
non-photochemical
-
carbamylation
- carboxylases
-
nadp-malic
- dikinase
-
oxygen-evolving
- biofuel production
- agriculture
The taxonomic range for the selected organisms is: Galdieria sulphuraria
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
rubisco, ribulose-1,5-bisphosphate carboxylase/oxygenase, ribulose-1,5-bisphosphate carboxylase, rubpcase, ribulose bisphosphate carboxylase, ribulose 1,5-bisphosphate carboxylase/oxygenase, ribulose 1,5-bisphosphate carboxylase, ribulose bisphosphate carboxylase/oxygenase, rubp carboxylase, rubisco small subunit, 
more
topSYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
Carboxydismutase
-
-
-
-
D-Ribulose 1,5-diphosphate carboxylase
-
-
-
-
D-Ribulose-1,5-bisphosphate carboxylase
-
-
-
-
Diphosphoribulose carboxylase
-
-
-
-
LESS17
-
-
-
-
PSS15
-
-
-
-
PSSU1
-
-
-
-
Ribulose 1,5-bisphosphate carboxylase
-
-
-
-
Ribulose 1,5-bisphosphate carboxylase-oxygenase
-
-
-
-
Ribulose 1,5-bisphosphate carboxylase/oxygenase
Ribulose 1,5-diphosphate carboxylase
-
-
-
-
Ribulose 1,5-diphosphate carboxylase/oxygenase
-
-
-
-
Ribulose bisphosphate carboxylase-oxygenase
-
-
-
-
Ribulose diphosphate carboxylase
-
-
-
-
Ribulose diphosphate carboxylase/oxygenase
-
-
-
-
Rubisco
RuBP carboxylase
-
-
-
-
Water stress responsive proteins 1, 2 and 14
-
-
-
-
Ribulose 1,5-bisphosphate carboxylase/oxygenase
-
-
-
-
Rubisco
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
carboxylation
-
-
-
-
oxygenation
-
-
-
-
PATHWAY SOURCE
PATHWAYS
BRENDA
KEGG
-
-, -, -
SYSTEMATIC NAME
IUBMB Comments
3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming)
Will utilize O2 instead of CO2, forming 3-phospho-D-glycerate and 2-phosphoglycolate.
CAS REGISTRY NUMBER
COMMENTARY
9027-23-0
-
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate + H+
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
first step in net photosynthetic CO2 assimilation and photorespiratory carbon oxidation, CO2 fixing enzyme that enables most forms of photo-and chemoautotrophic life
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
key enzyme responsible for photosynthetic carbon assimilation and photorespiratory carbon oxidation
-
?
D-ribulose 1,5-bisphosphate + O2
3-phospho-D-glycerate + 2-phosphoglycolate
-
-
-
?
D-ribulose 1,5-bisphosphate + O2
3-phospho-D-glycerate + 2-phosphoglycolate
-
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate + H+
-
-
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
first step in net photosynthetic CO2 assimilation and photorespiratory carbon oxidation, CO2 fixing enzyme that enables most forms of photo-and chemoautotrophic life
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
3-phospho-D-glycerate
-
key enzyme responsible for photosynthetic carbon assimilation and photorespiratory carbon oxidation
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
additional information
RuBisCO is inhibited by cysteine nitrosylation
-
additional information
-
RuBisCO is inhibited by cysteine nitrosylation
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
additional information
enzyme activation is carried out by treating the enzyme with 20 mM MgSO4 under CO2 atmosphere for an extended period (up to 24 h)
-
additional information
-
enzyme activation is carried out by treating the enzyme with 20 mM MgSO4 under CO2 atmosphere for an extended period (up to 24 h)
-
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). RBL_GALSU
493
0
54989
Swiss-Prot
other Location (Reliability: 2)
PDB
SCOP
CATH
UNIPROT
ORGANISM
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
hanging drop vapor diffusion method, in the presence of ammonium sulfate (about 2 M) and 2 mM Mg2+
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
L335V
-
directed mutagenesis, 60% decrease in relative specificity factor
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
John Andrews, T.; Whitney, S.M.
Manipulating ribulose bisphosphate carboxylase/oxygenase in the chloroplasts of higher plants
Arch. Biochem. Biophys.
414
159-169
2003
Synechocystis sp., Arabidopsis thaliana, Flaveria bidentis, Galdieria sulphuraria, Nicotiana tabacum, Oryza sativa, Phaeodactylum tricornutum, Rhodospirillum rubrum, Griffithsia monilis
Parry, M.A.; Andralojc, P.J.; Mitchell, R.A.; Madgwick, P.J.; Keys, A.J.
Manipulation of Rubisco: the amount, activity, function and regulation
J. Exp. Bot.
54
1321-1333
2003
Allochromatium vinosum, Arabidopsis thaliana, Avena sativa, Chlamydomonas reinhardtii, Cylindrotheca sp., Flaveria bidentis, Galdieria partita, Galdieria sulphuraria, Glycine max, Helianthus annuus, Hordeum vulgare, Solanum lycopersicum, Nicotiana tabacum, Olisthodiscus luteus, Oryza sativa, Petunia sp., Phaeodactylum tricornutum, Pisum sativum, Rhodobacter capsulatus, Cereibacter sphaeroides, Rhodospirillum rubrum, Spinacia oleracea, Triticum aestivum, Zea mays, Cylindrotheca sp. N1
Tcherkez, G.G.; Farquhar, G.D.; Andrews, T.J.
Despite slow catalysis and confused substrate specificity, all ribulose bisphosphate carboxylases may be nearly perfectly optimized
Proc. Natl. Acad. Sci. USA
103
7246-7251
2006
Allochromatium vinosum, Amaranthus hybridus, Trichormus variabilis, Chlamydomonas reinhardtii, Euglena gracilis, Galdieria sulphuraria, Nicotiana tabacum, Oryza sativa, Phaeodactylum tricornutum, Rhodospirillum rubrum, Sorghum bicolor, Spinacia oleracea, Synechococcus sp., Triticum aestivum, Zea mays, Griffithsia monilis, Atriplex glabriuscula, Synechococcus sp. 6301, Synechococcus sp. 7002
Witzel, F.; Goetze, J.; Ebenhoeh, O.
Slow deactivation of ribulose 1,5-bisphosphate carboxylase/oxygenase elucidated by mathematical models
FEBS J.
277
931-950
2010
Galdieria sulphuraria, Nicotiana tabacum, Phaeodactylum tricornutum, Rhodospirillum rubrum, Synechococcus sp., Griffithsia monilis
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