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Information on EC 4.1.1.35 - UDP-glucuronate decarboxylase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9LZI2

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.35 UDP-glucuronate decarboxylase
IUBMB Comments
Requires NAD+.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9LZI2
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
udp-glucuronic acid decarboxylase, udp-glucuronate decarboxylase, hvuxs1, udp-glca decarboxylase, osuxs3, osuxs2, hvuxs4, udp-d-glucuronate carboxy-lyase, hvuxs2, hvuxs3, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Decarboxylase, uridine diphosphoglucuronate
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UDP-glucuronate decarboxylase
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UDP-glucuronic acid decarboxylase
Q9LFG7
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UDPglucuronate carboxy-lyase
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Uridine diphosphate glucuronate carboxy-lyase
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Uridine-diphospho glucuronate decarboxylase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
decarboxylation
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)
Requires NAD+.
CAS REGISTRY NUMBER
COMMENTARY hide
9024-68-4
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-D-glucuronate
UDP-D-xylose + CO2
show the reaction diagram
Q9LFG7
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-
?
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.19
UDP-D-glucuronate
Q9LFG7
pH 7.4, 30°C
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.5 - 9.5
Q9LFG7
-
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
22 - 42
Q9LFG7
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
a triple mutant lacking the Golgi isoforms Uxs1 Usx2 Uxs4 shows no obvious phenotype
physiological function
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
UXS2_ARATH
445
1
49971
Swiss-Prot
other Location (Reliability: 1)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
42600
Q9LFG7
reombinant enzyme, SDS-PAGE
48300
Q9LFG7
predicted from amino acid sequence
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene AtUXS1 cDNA cloned and expressed in Escherichia coli BL21(DE3) pLysS
Q9LFG7
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Harper, A.D.; Bar-Peled, M.
Biosynthesis of UDP-xylose. Cloning and characterization of a novel Arabidopsis gene family, UXS, encoding soluble and putative membrane-bound UDP-glucuronic acid decarboxylase isoforms
Plant Physiol.
130
2188-2198
2002
Arabidopsis thaliana (Q9LFG7)
Manually annotated by BRENDA team
Kuang, B.; Zhao, X.; Zhou, C.; Zeng, W.; Ren, J.; Ebert, B.; Beahan, C.T.; Deng, X.; Zeng, Q.; Zhou, G.; Doblin, M.S.; Heazlewood, J.L.; Bacic, A.; Chen, X.; Wu, A.M.
Role of UDP-glucuronic acid decarboxylase in xylan biosynthesis in Arabidopsis
Mol. Plant
9
1119-1131
2016
Arabidopsis thaliana, Arabidopsis thaliana (Q8VZC0), Arabidopsis thaliana (Q9FIE8), Arabidopsis thaliana (Q9LZI2), Arabidopsis thaliana (Q9SN95), Arabidopsis thaliana (Q9ZV36)
Manually annotated by BRENDA team