Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 4.1.1.35 - UDP-glucuronate decarboxylase and Organism(s) Rattus norvegicus and UniProt Accession Q5PQX0

for references in articles please use BRENDA:EC4.1.1.35
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.35 UDP-glucuronate decarboxylase
IUBMB Comments
Requires NAD+.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Rattus norvegicus
UNIPROT: Q5PQX0
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
hide
The taxonomic range for the selected organisms is: Rattus norvegicus
The enzyme appears in selected viruses and cellular organisms
Synonyms
udp-glucuronic acid decarboxylase, udp-glucuronate decarboxylase, hvuxs1, udp-glca decarboxylase, osuxs2, osuxs3, hvuxs4, hvuxs2, hvuxs3, udp-d-glucuronate carboxy-lyase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
UDP-glucuronate decarboxylase
-
Decarboxylase, uridine diphosphoglucuronate
-
-
-
-
UDP-glucuronate decarboxylase
-
-
-
-
UDPglucuronate carboxy-lyase
-
-
-
-
Uridine diphosphate glucuronate carboxy-lyase
-
-
-
-
Uridine-diphospho glucuronate decarboxylase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
decarboxylation
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)
Requires NAD+.
CAS REGISTRY NUMBER
COMMENTARY hide
9024-68-4
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-D-glucuronate
UDP-D-xylose + CO2
show the reaction diagram
-
-
?
additional information
?
-
key enzyme in proteoglycan synthesis
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
key enzyme in proteoglycan synthesis
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
rat
Uniprot
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
UXS1_RAT
420
1
47539
Swiss-Prot
Mitochondrion (Reliability: 5)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
47000
Western blot
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
cloned and expressed in bacteria and transfected HEK293T cells
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Moriarity, J.L.; Hurt, K.J.; Resnick, A.C.; Storm, P.B.; Laroy, W.; Schnaar, R.L.; Snyder, S.H.
UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization
J. Biol. Chem.
277
16968-16975
2002
Rattus norvegicus (Q5PQX0)
Manually annotated by BRENDA team