Disease on EC 4.1.1.31 - phosphoenolpyruvate carboxylase
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Acidosis
Acid Loading Unmasks Glucose Homeostatic Instability in Proximal-Tubule-Targeted Insulin/Insulin-Like-Growth-Factor-1 Receptor Dual Knockout Mice.
Acidosis
cAMP-dependent stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK1-F+ kidney cells.
Acidosis
Changes in mRNAs for enzymes of glutamine metabolism in kidney and liver during ammonium chloride acidosis.
Acidosis
Changes in renal metabolite profile and ammoniagenesis during acute and chronic metabolic acidosis in dog and rat.
Acidosis
Concurrent binding and modifications of AUF1 and HuR mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells.
Acidosis
Development of ammonia and glucose productions from glutamine in foetal rat kidney; effects of metabolic acidosis.
Acidosis
Differential expression and acid-base regulation of glutaminase mRNAs in gluconeogenic LLC-PK(1)-FBPase(+) cells.
Acidosis
Distribution along the rat nephron of three enzymes of gluconeogenesis in acidosis and starvation.
Acidosis
Effect of acidosis on phosphoenolpyruvate carboxykinase and glutaminase mRNAs in rat kidney and in LLC-PK-F+ cells.
Acidosis
Effect of acute alterations in acid-base balance on rat renal glutaminase and phosphoenolpyruvate carboxykinase gene expression.
Acidosis
Effect of collecting duct-specific deletion of both Rh B Glycoprotein (Rhbg) and Rh C Glycoprotein (Rhcg) on renal response to metabolic acidosis.
Acidosis
Effect of stress on hepatic 11beta-hydroxysteroid dehydrogenase activity and its influence on carbohydrate metabolism.
Acidosis
Effects of metabolic acidosis and diabetes on the abundance of specific renal mRNAs.
Acidosis
Hepatic 11 beta-hydroxysteroid dehydrogenase 1 involvement in alterations of glucose metabolism produced by acidotic stress in rat.
Acidosis
Hormonal and acid-base regulation of phosphoenolpyruvate carboxykinase mRNA levels in rat kidney.
Acidosis
Induction of Phosphoenolpyruvate Carboxykinase (PEPCK) during Acute Acidosis and Its Role in Acid Secretion by V-ATPase-Expressing Ionocytes.
Acidosis
Induction of renal phosphoenolpyruvate carboxykinase mRNA: suppressive effect of glucose.
Acidosis
Influence of phosphoenolpyruvate carboxykinase inhibition on the response of NH3 production to acute acidosis.
Acidosis
Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis.
Acidosis
Involvement of glucocorticoids in the stimulation of rat kidney phosphoenolpyruvate carboxykinase activity after liver intoxication by carbon tetrachloride.
Acidosis
Localization and hormonal control of serine dehydratase during metabolic acidosis differ markedly from those of phosphoenolpyruvate carboxykinase in rat kidney.
Acidosis
Mechanism of altered renal glutaminase gene expression in response to chronic acidosis.
Acidosis
Messenger RNA for renal phosphoenolpyruvate carboxykinase (GTP). Its translation in a heterologous cell-free system and its regulation by glucocorticoids and by changes in acid-base balance.
Acidosis
p38 MAPK mediates acid-induced transcription of PEPCK in LLC-PK(1)-FBPase(+) cells.
Acidosis
PEPCK mRNA localization in proximal tubule and gene regulation during metabolic acidosis.
Acidosis
pH-responsive, gluconeogenic renal epithelial LLC-PK1-FBPase+cells: a versatile in vitro model to study renal proximal tubule metabolism and function.
Acidosis
Phosphoenolpyruvate carboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in early insulin resistance and diabetes.
Acidosis
Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis.
Acidosis
Regulation of phosphoenolpyruvate carboxykinase mRNA in mouse liver, kidney, and fat tissues by fasting, diabetes, and insulin.
Acidosis
Renal enzymes during experimental diabetes mellitus in the rat. Role of insulin, carbohydrate metabolism, and ketoacidosis.
Acidosis
Renal phosphoenolpyruvate carboxykinase during perturbations of acid-base homeostasis in rats. Immunochemical studies.
Acidosis
Role of AUF1 and HuR in the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK1-F+ cells.
Acidosis
RT-PCR localization of phosphoenolpyruvate carboxykinase in the proximal tubule of the rat during metabolic acidosis.
Acidosis
Significance of the intracellular distribution of phosphoenolpyruvate carboxykinase in acidosis.
Acidosis
The effect of steroids and ammonium chloride acidosis on phosphoenolpyruvate carboxykinase in rat kidney cortex. I. Differentiation of the inductive process and characterization of enzyme activities.
Acidosis
The effect of steroids and ammonium chloride acidosis on phosphoenolpyruvate carboxykinase in rat kidney cortex. II. The kinetics of enzyme induction.
Acidosis
The kidney of chicken adapts to chronic metabolic acidosis: in vivo and in vitro studies.
Acidosis
[Stimulation of gluconeogenic capacity in partially hepatectomized rats (author's transl)]
Acidosis, Lactic
Cytosolic Phosphoenolpyruvate Carboxykinase Deficiency: Cause of Hypoglycemia-Induced Seizure and Death.
Acidosis, Lactic
Lactic acidosis and renal phosphoenolpyruvate carboxykinase activity during exercise.
Acidosis, Lactic
Novel missense variants in PCK1 gene cause cytosolic PEPCK deficiency with growth failure from inadequate caloric intake.
Acidosis, Lactic
Overcoming diabetes-induced hyperglycemia through inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP) with RNAi.
Adenoma
Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice.
Adenoviridae Infections
Adenovirus E1A represses the cyclic AMP-induced transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in hepatoma cells.
Bacterial Infections
Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected by Anaplasma phagocytophilum Infection in Tick Cells.
Brain Ischemia
Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia.
Breast Cyst
Quantification of pepsinogen C and prostaglandin D synthase in breast cyst fluid and their potential utility for cyst type classification.
Breast Neoplasms
Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis.
Breast Neoplasms
Expression of androgen receptor and two androgen-induced proteins (apolipoprotein D and pepsinogen C) in ductal carcinoma in situ of the breast.
Breast Neoplasms
Immunoenzymatically determined pepsinogen C concentration in breast tumor cytosols: an independent favorable prognostic factor in node-positive patients.
Breast Neoplasms
Quantification of pepsinogen C and prostaglandin D synthase in breast cyst fluid and their potential utility for cyst type classification.
Breast Neoplasms
Screening of core genes and pathways in breast cancer development via comprehensive analysis of multi gene expression datasets.
Carcinoma
Association of phosphoenolpyruvate carboxykinase 1 protein kinase activity-dependent sterol regulatory element-binding protein 1 activation with prognosis of oesophageal carcinoma.
Carcinoma
Expression of androgen receptor and two androgen-induced proteins (apolipoprotein D and pepsinogen C) in ductal carcinoma in situ of the breast.
Carcinoma, Hepatocellular
3-Aminobenzamide inhibits poly(ADP ribose) synthetase activity and induces phosphoenolpyruvate carboxykinase (GTP) in H4IIE hepatoma cells.
Carcinoma, Hepatocellular
5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase.
Carcinoma, Hepatocellular
5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor.
Carcinoma, Hepatocellular
A novel role of bone morphogenetic protein 6 (BMP6) in glucose homeostasis.
Carcinoma, Hepatocellular
A point mutation of the AF2 transactivation domain of the glucocorticoid receptor disrupts its interaction with steroid receptor coactivator 1.
Carcinoma, Hepatocellular
A selective system for hepatoma cells producing gluconeogenic enzymes.
Carcinoma, Hepatocellular
Activation of the ras mitogen-activated protein kinase-ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin.
Carcinoma, Hepatocellular
Activities of key gluconeogenic enzymes and glycogen synthase in rat and human livers, hepatomas, and hepatoma cell cultures.
Carcinoma, Hepatocellular
Acute and chronic regulation of phosphoenolpyruvate carboxykinase mRNA by insulin and glucose.
Carcinoma, Hepatocellular
Adenovirus E1A proteins regulate phosphoenolpyruvate carboxykinase gene transcription through multiple mechanisms.
Carcinoma, Hepatocellular
Adenovirus E1A represses the cyclic AMP-induced transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in hepatoma cells.
Carcinoma, Hepatocellular
Adiponectin represses gluconeogenesis independent of insulin in hepatocytes.
Carcinoma, Hepatocellular
An extract of Syzygium aromaticum represses genes encoding hepatic gluconeogenic enzymes.
Carcinoma, Hepatocellular
Bioactive polyphenols in kinkéliba tea (Combretum micranthum) and their glucose-lowering activities.
Carcinoma, Hepatocellular
C/EBP? is AMP kinase sensitive and up-regulates PEPCK in response to ER stress in hepatoma cells.
Carcinoma, Hepatocellular
CCAAT/enhancer-binding protein alpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase.
Carcinoma, Hepatocellular
Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene.
Carcinoma, Hepatocellular
Characterization of the binding sites for [3H]glibenclamide in rat liver membranes.
Carcinoma, Hepatocellular
Comparison of the effects of insulin and okadaic acid on phosphoenolpyruvate carboxykinase gene expression.
Carcinoma, Hepatocellular
Culture at high density increases phosphoenolpyruvate carboxykinase messenger RNA in H4IIEC3 hepatoma cells.
Carcinoma, Hepatocellular
Cyclic AMP stabilizes the mRNA for phosphoenolpyruvate carboxykinase (GTP) against degradation.
Carcinoma, Hepatocellular
Different transcription factor binding arrays modulate the cAMP responsivity of the phosphoenolpyruvate carboxykinase gene promoter.
Carcinoma, Hepatocellular
Differential activity of a tissue-specific extinguisher locus in hepatic and nonhepatic cells.
Carcinoma, Hepatocellular
Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells.
Carcinoma, Hepatocellular
Dual specificity MAPK phosphatase 3 activates PEPCK gene transcription and increases gluconeogenesis in rat hepatoma cells.
Carcinoma, Hepatocellular
Effects of 6- and 8-substituted analogs of adenosine 3':5'-monophosphate on phosphoenolpyruvate carboxykinase and tyrosine aminotransferase in hepatoma cell cultures.
Carcinoma, Hepatocellular
Effects of amino acid analogues on protein synthesis and degradation in isolated cells.
Carcinoma, Hepatocellular
Effects of catechin-rich green tea on gene expression of gluconeogenic enzymes in rat hepatoma H4IIE cells.
Carcinoma, Hepatocellular
Effects of cyclic adenosine monophosphate, dexamethasone and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells.
Carcinoma, Hepatocellular
Effects of nipradilol, a nitric oxide-releasing beta-adrenoceptor blocking agent, on phosphoenolpyruvate carboxykinase gene transcription in a rat hepatoma cell line.
Carcinoma, Hepatocellular
Efficient delivery of siRNA using dendritic poly(L-lysine) for loss-of-function analysis.
Carcinoma, Hepatocellular
Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases cAMP-stimulated hepatic gluconeogenesis via inhibition of CREB.
Carcinoma, Hepatocellular
Enhancement of phenotypic expression in cultured malignant liver epithelial cells by a complex medium.
Carcinoma, Hepatocellular
Evidence for selective induction of phosphoenolpyruvate carboxykinase gene expression by unsaturated and nonmetabolized fatty acids in adipocytes.
Carcinoma, Hepatocellular
Expression of the phosphoenolpyruvate carboxykinase gene and its insulin regulation during differentiation of preadipose cell lines.
Carcinoma, Hepatocellular
Extinction of phosphoenolpyruvate carboxykinase gene expression is associated with loss of a specific chromatin-binding protein from a far upstream domain.
Carcinoma, Hepatocellular
Genetic activity of a trans-regulatory locus in hepatoma hybrid cells.
Carcinoma, Hepatocellular
Gentiopicroside and sweroside from Veratrilla baillonii Franch. induce phosphorylation of Akt and suppress Pck1 expression in hepatoma cells.
Carcinoma, Hepatocellular
Gi alpha 2 mediates the inhibitory regulation of adenylylcyclase in vivo: analysis in transgenic mice with Gi alpha 2 suppressed by inducible antisense RNA.
Carcinoma, Hepatocellular
Glucocorticoids use a positive liver element to repress fibrate-induced adipose transcription of the phosphoenolpyruvate carboxykinase gene.
Carcinoma, Hepatocellular
Glucokinase expression in rat hepatoma cells induces glucose uptake and is rate limiting in glucose utilization.
Carcinoma, Hepatocellular
Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose deprivation.
Carcinoma, Hepatocellular
Hepatic gluconeogenic key enzymes in patients with hepatic cancer.
Carcinoma, Hepatocellular
Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes.
Carcinoma, Hepatocellular
Hormonal control of interacting promoters introduced into cells by retroviruses.
Carcinoma, Hepatocellular
Hormonal regulation of chimeric genes containing the phosphoenolpyruvate carboxykinase promoter regulatory region in hepatoma cells infected by murine retroviruses.
Carcinoma, Hepatocellular
Hormonal regulation of phosphoenolpyruvate carboxykinase gene expression is mediated through modulation of an already disrupted chromatin structure.
Carcinoma, Hepatocellular
Hormonal regulation of the phosphoenolpyruvate carboxykinase gene. Role of specific CCAAT/enhancer-binding protein isoforms.
Carcinoma, Hepatocellular
Human evidence for the involvement of insulin-induced gene 1 in the regulation of plasma glucose concentration.
Carcinoma, Hepatocellular
Hypoglycemic effects of brassinosteroid in diet-induced obese mice.
Carcinoma, Hepatocellular
Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice.
Carcinoma, Hepatocellular
Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Impaired suppression of gluconeogenesis induced by overexpression of a noninsulin-responsive phosphoenolpyruvate carboxykinase gene.
Carcinoma, Hepatocellular
Inhibition by insulin of protein kinase A-induced transcription of the phosphoenolpyruvate carboxykinase gene. Mediation by the activation domain of cAMP response element-binding protein (CREB) and factors bound to the TATA box.
Carcinoma, Hepatocellular
Inhibitors of signalling identify differential control processes responsible for selective effects of insulin on the expression of phosphoenolpyruvate carboxykinase and gene 33 in rat H4 hepatoma cells.
Carcinoma, Hepatocellular
Insulin decreases H4IIE cell PEPCK mRNA by a mechanism that does not involve cAMP.
Carcinoma, Hepatocellular
Insulin decreases phosphoenolpyruvate carboxykinase (GTP) mRNA activity by a receptor-mediated process.
Carcinoma, Hepatocellular
Insulin pulses less effective than continuous insulin in inhibiting PEPCK mRNA levels stimulated by cAMP and dexamethasone in perifused hepatoma cells.
Carcinoma, Hepatocellular
Insulin represses phosphoenolpyruvate carboxykinase gene transcription by causing the rapid disruption of an active transcription complex: a potential epigenetic effect.
Carcinoma, Hepatocellular
Insulin-like effects of inositol phosphate-glycan on messenger RNA expression in rat hepatocytes.
Carcinoma, Hepatocellular
Interaction of a liver-specific factor with an enhancer 4.8 kilobases upstream of the phosphoenolpyruvate carboxykinase gene.
Carcinoma, Hepatocellular
Interaction of trans-acting factors and re-expression of liver functions in hepatoma hybrid cells.
Carcinoma, Hepatocellular
Knockdown of the Sonic Hedgehog (SHH) Gene Inhibits Proliferation of Hep3B and SMMC-7721 Hepatocellular Carcinoma Cells via the PI3K/Akt/PCK1 Signaling Pathway.
Carcinoma, Hepatocellular
Lithium inhibits hepatic gluconeogenesis and phosphoenolpyruvate carboxykinase gene expression.
Carcinoma, Hepatocellular
Liver x receptors regulate the transcriptional activity of the glucocorticoid receptor: implications for the carbohydrate metabolism.
Carcinoma, Hepatocellular
Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene.
Carcinoma, Hepatocellular
Loss of TR4 orphan nuclear receptor reduces phosphoenolpyruvate carboxykinase-mediated gluconeogenesis.
Carcinoma, Hepatocellular
Melatonin stimulates transcription of the rat phosphoenolpyruvate carboxykinase gene in hepatic cells.
Carcinoma, Hepatocellular
Modulation of phosphoenolpyruvate carboxykinase mRNA levels by the hepatocellular hydration state.
Carcinoma, Hepatocellular
Molecular basis for effects of carcinogenic heavy metals on inducible gene expression.
Carcinoma, Hepatocellular
Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone.
Carcinoma, Hepatocellular
Multiple elements regulate phosphoenolpyruvate carboxykinase gene expression in hepatoma hybrid cells.
Carcinoma, Hepatocellular
Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation.
Carcinoma, Hepatocellular
Oxidative and chemical stress mimic insulin by selectively inhibiting the expression of phosphoenolpyruvate carboxykinase in hepatoma cells.
Carcinoma, Hepatocellular
Oxidative Stress Induces Phosphoenolpyruvate Carboxykinase Expression in H4IIE Cells.
Carcinoma, Hepatocellular
PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis.
Carcinoma, Hepatocellular
Phenolic Diterpenes from Rosemary Suppress cAMP Responsiveness of Gluconeogenic Gene Promoters.
Carcinoma, Hepatocellular
Phosphoenolpyruvate carboxykinase is induced in growth-arrested hepatoma cells.
Carcinoma, Hepatocellular
Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription.
Carcinoma, Hepatocellular
Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line.
Carcinoma, Hepatocellular
Properties of phosphoenolpyruvate carboxykinase (guanosine triphosphate) synthesized in hepatoma cells in the presence of amino acid analogues.
Carcinoma, Hepatocellular
Protein synthesis and insulin regulation of p33 and PEPCK gene expression.
Carcinoma, Hepatocellular
Proteomic Analysis of Hepatocellular Carcinoma Tissues With Encapsulation Shows Up-regulation of Leucine Aminopeptidase 3 and Phosphoenolpyruvate Carboxykinase 2.
Carcinoma, Hepatocellular
Purification and characterization of insulin-mimetic inositol phosphoglycan-like molecules from grass pea (Lathyrus sativus) seeds.
Carcinoma, Hepatocellular
Reciprocal regulation of gene transcription by insulin. Inhibition of the phosphoenolpyruvate carboxykinase gene and stimulation of gene 33 in a single cell type.
Carcinoma, Hepatocellular
Regulation of carbohydrate metabolism by the farnesoid X receptor.
Carcinoma, Hepatocellular
Regulation of chimeric phosphoenolpyruvate carboxykinase genes by the trans-dominant locus TSE1.
Carcinoma, Hepatocellular
Regulation of gene expression in rat hepatocytes and hepatoma cells by insulin: quantitation of messenger ribonucleic acid's coding for tyrosine aminotransferase, tryptophan oxygenase, and phosphoenolpyruvate carboxykinase.
Carcinoma, Hepatocellular
Regulation of phosphoenolpyruvate carboxykinase and tyrosine transaminase in hepatoma cell cultures. 3. Comparative studies in H35, HTC, MH1C1 and RLC cells.
Carcinoma, Hepatocellular
Regulation of phosphoenolpyruvate carboxykinase and tyrosine transaminase in hepatoma cell cultures. I. Effects of glucocorticoids, N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate and insulin in Reuber H35 cells.
Carcinoma, Hepatocellular
Regulation of phosphoenolpyruvate carboxykinase gene transcription by insulin and cAMP: reciprocal actions on initiation and elongation.
Carcinoma, Hepatocellular
Regulation of phosphoenolpyruvate carboxykinase gene transcription in H4IIE hepatoma cells: evidence for a primary role of the catalytic subunit of 3',5'-cyclic adenosine monophosphate-dependent protein kinase.
Carcinoma, Hepatocellular
Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP).
Carcinoma, Hepatocellular
Repression and activation of transcription of phosphoenolpyruvate carboxykinase gene during liver development.
Carcinoma, Hepatocellular
Repression of phosphoenolpyruvate carboxykinase gene activity by insulin is blocked by 3-aminobenzamide but not by PD128763, a selective inhibitor of poly(ADP-ribose) polymerase.
Carcinoma, Hepatocellular
Response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids depends on the integrity of the cAMP pathway.
Carcinoma, Hepatocellular
Separate cis-regulatory elements confer expression of phosphoenolpyruvate carboxykinase (GTP) gene in different cell lines.
Carcinoma, Hepatocellular
Specificity of a retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter: consequences of both retinoic acid and thyroid hormone receptor binding.
Carcinoma, Hepatocellular
Stimulation of phosphoenolpyruvate carboxykinase gene expression by fatty acids.
Carcinoma, Hepatocellular
Structural constraints and importance of caffeic acid moiety for anti-hyperglycemic effects of caffeoylquinic acids from chicory.
Carcinoma, Hepatocellular
Suppression of phosphoenolpyruvate carboxykinase gene expression by reduced endogenous glutathione level.
Carcinoma, Hepatocellular
The 5'region of the rat phosphoenolpyruvate carboxykinase gene confers pH sensitivity to chimeric genes expressed in renal and liver cell lines capable of expressing PEPCK.
Carcinoma, Hepatocellular
The alpha-isoform of the CCAAT/enhancer-binding protein is required for mediating cAMP responsiveness of the phosphoenolpyruvate carboxykinase promoter in hepatoma cells.
Carcinoma, Hepatocellular
The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
Carcinoma, Hepatocellular
The inhibition of phosphoenolpyruvate carboxykinase (guanosine triphosphate) gene expression by insulin is not mediated by protein kinase C.
Carcinoma, Hepatocellular
The inhibitory effect of tolbutamide on phosphoenolpyruvate carboxykinase activity in rat hepatoma H4IIE cells.
Carcinoma, Hepatocellular
The liver-enriched transcription factor D-site-binding protein activates the promoter of the phosphoenolpyruvate carboxykinase gene in hepatoma cells.
Carcinoma, Hepatocellular
The molecular physiology of hepatic nuclear factor 3 in the regulation of gluconeogenesis.
Carcinoma, Hepatocellular
The oncoprotein HBXIP suppresses gluconeogenesis through modulating PCK1 to enhance the growth of hepatoma cells.
Carcinoma, Hepatocellular
The oxazolidinedione CP-92,768-2 partially protects insulin receptor substrate-1 from dexamethasone down-regulation in 3T3-L1 adipocytes.
Carcinoma, Hepatocellular
The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
The repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolism.
Carcinoma, Hepatocellular
The role of protein synthesis in the decay of phosphoenolpyruvate carboxykinase messenger RNA.
Carcinoma, Hepatocellular
The synergistic effect of dexamethasone and all-trans-retinoic acid on hepatic phosphoenolpyruvate carboxykinase gene expression involves the coactivator p300.
Carcinoma, Hepatocellular
The use of Reuber hepatoma cells for the study of a lipopolysaccharide-induced macrophage factor: glucocorticoid-antagonizing factor.
Carcinoma, Hepatocellular
Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq.
Carcinoma, Hepatocellular
Two Alkaloids from Bulbs of Lycoris sanguinea MAXIM. Suppress PEPCK Expression by Inhibiting the Phosphorylation of CREB.
Carcinoma, Hepatocellular
Unmetabolized fenofibrate, but not fenofibric acid, activates AMPK and inhibits the expression of phosphoenolpyruvate carboxykinase in hepatocytes.
Carcinoma, Hepatocellular
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.
Carcinoma, Hepatocellular
Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice.
Carcinoma, Hepatocellular
[Effect of insulin, cAMP, and dexamethasone on phosphoenolpyruvate carboxykinase gene promoter in vitro]
Carcinoma, Intraductal, Noninfiltrating
Expression of androgen receptor and two androgen-induced proteins (apolipoprotein D and pepsinogen C) in ductal carcinoma in situ of the breast.
Carcinoma, Non-Small-Cell Lung
Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer.
Carcinoma, Non-Small-Cell Lung
PCK2 activation mediates an adaptive response to glucose depletion in lung cancer.
Chagas Disease
Phosphoenolpyruvate carboxykinase from T. cruzi magnetic beads affinity-based screening assays on crude plant extracts from Brazilian Cerrado.
Cholestasis
Reduction in phosphoenolpyruvate carboxykinase in rat liver parenchymal cells following experimentally induced cholestasis.
Colonic Neoplasms
Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells.
Colonic Neoplasms
Glucose-dependent transcriptional regulation of the human sucrase-isomaltase (SI) gene.
Colonic Neoplasms
Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor.
Colorectal Neoplasms
Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer.
Confusion
New partial sequences of phosphoenolpyruvate carboxylase as molecular phylogenetic markers.
Cryptococcosis
Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host.
Cystic Fibrosis
Involvement of hepatocyte nuclear factor 3 in endoderm differentiation of embryonic stem cells.
Cystic Fibrosis
Microarray analysis reveals the inhibition of intestinal expression of nutrient transporters in piglets infected with porcine epidemic diarrhea virus.
Cystic Fibrosis
Phenotypic plasticity in gene expression and physiological response in red drum Sciaenops ocellatus exposed to a long-term freshwater environment.
Cysts
Effect of antihydatid drugs on carbohydrate metabolism of metacestode of echinococcus granulosus.
Cysts
Effects of mebendazole, albendazole, and praziquantel on fumarate hydratase, pyruvate kinase, and phosphoenolpyruvate carboxykinase of Echinococcus granulosus cyst wall harbored in mice.
Cysts
Quantification of pepsinogen C and prostaglandin D synthase in breast cyst fluid and their potential utility for cyst type classification.
Dehydration
Evolutionary physiology: the extent of C4 and CAM photosynthesis in the genera Anacampseros and Grahamia of the Portulacaceae.
Dehydration
Expression of genes involved in energy mobilization and osmoprotectant synthesis during thermal and dehydration stress in the Antarctic midge, Belgica antarctica.
Dehydration
Induction of Crassulacean Acid Metabolism in the Facultative Halophyte Mesembryanthemum crystallinum by Abscisic Acid.
Dehydration
Leaf anatomy and photosynthetic carbon metabolic characteristics in Phragmites communis in different soil water availability
Dehydration
Nucleotide sequence of the lantibiotic Pep5 biosynthetic gene cluster and functional analysis of PepP and PepC. Evidence for a role of PepC in thioether formation.
Dehydration
Phosphoenolpyruvate carboxylase from pennywort (Umbilicus rupestris). Changes in properties after exposure to water stress.
Dehydration
Regulation of Phosphoenolpyruvate Carboxylase and Crassulacean Acid Metabolism Induction in Mesembryanthemum crystallinum L. by Cytokinin : Modulation of Leaf Gene Expression by Roots?
Dehydration
Regulation of phosphoenolpyruvate carboxylase in Pinus halepensis needles submitted to ozone and water stress.
Dehydration
Salt stress leads to differential expression of two isogenes of phosphoenolpyruvate carboxylase during Crassulacean acid metabolism induction in the common ice plant.
Dehydration
Sucrose phosphate synthase activity and the co-ordination of carbon partitioning during sucrose and amino acid accumulation in desiccation-tolerant leaf material of the C4 resurrection plant Sporobolus stapfianus during dehydration.
Dehydration
The activities of PEP carboxylase and the C(4) acid decarboxylases are little changed by drought stress in three C(4) grasses of different subtypes.
Dehydration
[Activity of NADP-dependent glyceraldehyde-phosphate dehydrogenase and phosphoenolpyruvate carboxylase in wheat leaves under water stress]
Dehydration
[Effect of water stress on phosphoenolpyruvate carboxylase activity in Mesembryanthemum crystallinum (L.)].
Dengue
Molecular dynamics study of the membrane interaction of a membranotropic dengue virus C protein-derived peptide.
Diabetes Mellitus
A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene.
Diabetes Mellitus
Amelioration of glucose homeostasis by glycyrrhizic acid through gluconeogenesis rate-limiting enzymes.
Diabetes Mellitus
Association of the promoter polymorphism -232C/G of the phosphoenolpyruvate carboxykinase gene (PCK1) with Type 2 diabetes mellitus.
Diabetes Mellitus
Dynamic Behavior of Rat Phosphoenolpyruvate Carboxykinase Inhibitors: New Mechanism for Enzyme Inhibition.
Diabetes Mellitus
Establishment of a canine model of human type 2 diabetes mellitus by overexpressing phosphoenolypyruvate carboxykinase.
Diabetes Mellitus
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes.
Diabetes Mellitus
Generation of fibroblasts overexpressing liver-specific PEPCK in a miniature pig model of human type 2 diabetes mellitus.
Diabetes Mellitus
Hepatic phosphoenolpyruvate carboxykinase expression after gastric bypass surgery in rats with type 2 diabetes mellitus.
Diabetes Mellitus
Hybrid of 1-deoxynojirimycin and polysaccharide from mulberry leaves treat diabetes mellitus by activating PDX-1/insulin-1 signaling pathway and regulating the expression of glucokinase, phosphoenolpyruvate carboxykinase and glucose-6-phosphatase in alloxan-induced diabetic mice.
Diabetes Mellitus
Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants.
Diabetes Mellitus
New approach in the treatment of T2DM and metabolic syndrome (focus on a novel insulin sensitizer).
Diabetes Mellitus
Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice.
Diabetes Mellitus
PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats.
Diabetes Mellitus
Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus.
Diabetes Mellitus
Relationships of SLC2A4, RBP4, PCK1, and PI3K Gene Polymorphisms with Gestational Diabetes Mellitus in a Chinese Population.
Diabetes Mellitus
Structural and functional analysis of the human phosphoenolpyruvate carboxykinase gene promoter.
Diabetes Mellitus
The characteristics of hepatic Gs?-cAMP axis in HSHF diet-fed obese insulin resistance rats and genetic diabetic mice.
Diabetes Mellitus
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Diabetes Mellitus, Type 2
A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin.
Diabetes Mellitus, Type 2
A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene.
Diabetes Mellitus, Type 2
Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes.
Diabetes Mellitus, Type 2
Adipose overexpression of phosphoenolpyruvate carboxykinase leads to high susceptibility to diet-induced insulin resistance and obesity.
Diabetes Mellitus, Type 2
Amelioration of glucose homeostasis by glycyrrhizic acid through gluconeogenesis rate-limiting enzymes.
Diabetes Mellitus, Type 2
Association of the promoter polymorphism -232C/G of the phosphoenolpyruvate carboxykinase gene (PCK1) with Type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young.
Diabetes Mellitus, Type 2
Central Administration of Resveratrol Improves Diet-Induced Diabetes.
Diabetes Mellitus, Type 2
Dapagliflozin suppresses glucagon signaling in rodent models of diabetes.
Diabetes Mellitus, Type 2
Ergostatrien-3?-ol from Antrodia camphorata Inhibits Diabetes and Hyperlipidemia in High-Fat-Diet Treated Mice via Regulation of Hepatic Related Genes, Glucose Transporter 4, and AMP-Activated Protein Kinase Phosphorylation.
Diabetes Mellitus, Type 2
Establishment of a canine model of human type 2 diabetes mellitus by overexpressing phosphoenolypyruvate carboxykinase.
Diabetes Mellitus, Type 2
Examination of the phosphoenolpyruvate carboxykinase gene promoter in patients with noninsulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue: induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes.
Diabetes Mellitus, Type 2
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes.
Diabetes Mellitus, Type 2
Generation of fibroblasts overexpressing liver-specific PEPCK in a miniature pig model of human type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Hepatic phosphoenolpyruvate carboxykinase expression after gastric bypass surgery in rats with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Hypoglycemic effect of protopanaxadiol-type ginsenosides and compound K on Type 2 Diabetes mice induced by high-fat diet combining with streptozotocin via suppression of hepatic gluconeogenesis.
Diabetes Mellitus, Type 2
Identification of a novel variant in the phosphoenolpyruvate carboxykinase gene promoter in Japanese patients with type 2 diabetes.
Diabetes Mellitus, Type 2
Indication for genetic linkage of the phosphoenolpyruvate carboxykinase (PCK1) gene region on chromosome 20q to non-insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression.
Diabetes Mellitus, Type 2
Kinetic characterization of recombinant human cytosolic phosphoenolpyruvate carboxykinase with and without a His(10)-tag.
Diabetes Mellitus, Type 2
Large-scale study of the -232C > G polymorphism of PCK1 in Type 2 diabetes.
Diabetes Mellitus, Type 2
Mixed Inhibition of cPEPCK by Genistein, Using an Extended Binding Site Located Adjacent to Its Catalytic Cleft.
Diabetes Mellitus, Type 2
Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice.
Diabetes Mellitus, Type 2
PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats.
Diabetes Mellitus, Type 2
Promoter polymorphism in PCK1 (phosphoenolpyruvate carboxykinase gene) associated with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Regulation of glyceroneogenesis and phosphoenolpyruvate carboxykinase by fatty acids, retinoic acids and thiazolidinediones: potential relevance to type 2 diabetes.
Diabetes Mellitus, Type 2
Relationships of SLC2A4, RBP4, PCK1, and PI3K Gene Polymorphisms with Gestational Diabetes Mellitus in a Chinese Population.
Diabetes Mellitus, Type 2
Search for a third susceptibility gene for maturity-onset diabetes of the young. Studies with eleven candidate genes.
Diabetes Mellitus, Type 2
STAT3 targets the regulatory regions of gluconeogenic genes in vivo.
Diabetes Mellitus, Type 2
Structural and functional analysis of the human phosphoenolpyruvate carboxykinase gene promoter.
Diabetes Mellitus, Type 2
The characteristics of hepatic Gs?-cAMP axis in HSHF diet-fed obese insulin resistance rats and genetic diabetic mice.
Diabetes Mellitus, Type 2
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Diabetes Mellitus, Type 2
The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population.
Diabetes Mellitus, Type 2
Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
[Effects of Astragalus membranaceus and Potentilla discolor mixture on insulin resistance and its related mRNA expressions in KKAy mice with type 2 diabetes].
Diabetes Mellitus, Type 2
[The role of arecoline on hepatic insulin resistance in type 2 diabetes rats].
Dyslipidemias
Forced internal desynchrony induces cardiometabolic alterations in adult rats.
Endotoxemia
Altered transcriptional regulation of phosphoenolpyruvate carboxykinase in rats following endotoxin treatment.
Endotoxemia
Efficacy of anti-tumor necrosis factor polyclonal antibody on phosphoenolpyruvate carboxykinase expression in septic and endotoxemic rats.
Endotoxemia
Excessive NO production dose not account for the inhibition of hepatic gluconeogenesis in endotoxemia.
Endotoxemia
Failure of glucagon to induce hepatic phosphoenolpyruvate carboxykinase in endotoxic shock.
Endotoxemia
Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice.
Endotoxemia
[The effect of endotoxemia on gluconeogenesis in livers and kidneys during acute hepatic failure.]
Fatty Liver
Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats.
Fatty Liver
Dual SGLT1/SGLT2 Inhibitor Phlorizin Ameliorates Non-Alcoholic Fatty Liver Disease and Hepatic Glucose Production in Type 2 Diabetic Mice.
Fatty Liver
Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis.
Fatty Liver
Overcoming diabetes-induced hyperglycemia through inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP) with RNAi.
Fatty Liver
Regulation of messenger ribonucleic acid expression for gluconeogenic enzymes during glucagon infusions into lactating cows.
Fatty Liver
Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes.
Fatty Liver, Alcoholic
Effects of Acetaldehyde on Hepatocyte Glycerol Uptake and Cell Size: Implication of Aquaporin 9.
Fetal Growth Retardation
Phosphoenolpyruvate carboxykinase in experimental intrauterine growth retardation in rats.
Fetal Growth Retardation
The effect of dexamethasone and surgically induced intrauterine growth retardation on renal and hepatic levels of phosphoenolpyruvate carboxykinase in the rat.
Fetal Growth Retardation
[Effect of intrauterine growth retardation on gluconeogenic enzymes in rat liver].
Gastroenteritis
Cytosolic phosphoenolpyruvate carboxykinase deficiency presenting with acute liver failure following gastroenteritis.
Gastrointestinal Neoplasms
Tumor-associated metabolic alterations in patients with gastric and esophageal cancer.
Glucose Intolerance
18?-Glycyrrhetinic acid acts through hepatocyte nuclear factor 4 alpha to modulate lipid and carbohydrate metabolism.
Glucose Intolerance
A high-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice.
Glucose Intolerance
A primary defect in glucose production alone cannot induce glucose intolerance without defects in insulin secretion.
Glucose Intolerance
CILP-2 is a novel secreted protein and associated with insulin resistance.
Glucose Intolerance
Comparative Effects of the Renin-Angiotensin System Blockers on Nonalcoholic Fatty Liver Disease and Insulin Resistance in C57Bl/6 Mice.
Glucose Intolerance
Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure.
Glucose Intolerance
Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.
Glucose Intolerance
Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring.
Glucose Intolerance
Hypothalamic JNK1 and IKK? activation and impaired early postnatal glucose metabolism after maternal perinatal high-fat feeding.
Glucose Intolerance
Impaired glucose tolerance and increased weight gain in transgenic rats overexpressing a non-insulin-responsive phosphoenolpyruvate carboxykinase gene.
Glucose Intolerance
Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats.
Glucose Intolerance
Ketogenic diet-fed rats have increased fat mass and phosphoenolpyruvate carboxykinase activity.
Glucose Intolerance
Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.
Glucose Intolerance
Porcine adiponectin receptor 1 transgene resists high-fat/sucrose diet-induced weight gain, hepatosteatosis and insulin resistance in mice.
Glucose Intolerance
Prolonged fasting elicits increased hepatic triglyceride accumulation in rats born to dexamethasone-treated mothers.
Glycosuria
Thyroid hormone treatment decreases hepatic glucose production and renal reabsorption of glucose in alloxan-induced diabetic Wistar rats.
Hepatitis B
Direct binding of hepatitis B virus X protein and retinoid X receptor contributes to phosphoenolpyruvate carboxykinase gene transactivation.
Hepatitis B
Increased expression of phosphoenolpyruvate carboxykinase cytoplasmic isoform by hepatitis B virus X protein affects hepatitis B virus replication.
Hepatitis C
Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis.
Hepatitis C
Increased Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression and Steatosis During Hepatitis C Virus (HCV) Subgenome Replication: Role of Nonstructural Component-5A (NS5A) and CCAAT/Enhancer Binding Protein ?(C/EBP?).
Hepatitis, Chronic
Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis.
Hepatoblastoma
Regulation by glucagon (cAMP) and insulin of the promoter of the human phosphoenolpyruvate carboxykinase gene (cytosolic) in cultured rat hepatocytes and in human hepatoblastoma cells.
Herpes Simplex
Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. I. Multiple hormone regulatory elements and the effects of enhancers.
Herpes Simplex
Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains.
Herpes Simplex
Identification of a cAMP regulatory region in the gene for rat cytosolic phosphoenolpyruvate carboxykinase (GTP). Use of chimeric genes transfected into hepatoma cells.
Herpes Simplex
Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma.
Herpes Simplex
The role of the TATA box in the hormonal regulation of phosphoenolpyruvate carboxykinase gene expression.
Herpes Zoster
Establishment and characterisation of a novel bovine SV40 large T-antigen-transduced foetal hepatocyte-derived cell line.
Hyperglycemia
A high-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice.
Hyperglycemia
A potential probiotic bacterium for antipsychotic-induced metabolic syndrome: mechanisms underpinning how Akkermansia muciniphila subtype improves olanzapine-induced glucose homeostasis in mice.
Hyperglycemia
A synthetic Nitraria alkaloid, isonitramine protects pancreatic ?-cell and attenuates postprandial hyperglycemia.
Hyperglycemia
An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.
Hyperglycemia
Anti-diabetic effects of new herbal formula in neonatally streptozotocin-induced diabetic rats.
Hyperglycemia
Antidiabetic and Antihyperlipidemic Properties of a Triterpenoid Compound, Dehydroeburicoic Acid, from Antrodia camphorata in Vitro and in Streptozotocin-Induced Mice.
Hyperglycemia
Biochemical evidence on the potential role of organophosphates in hepatic glucose metabolism toward insulin resistance through inflammatory signaling and free radical pathways.
Hyperglycemia
Carbon flux via the pentose phosphate pathway regulates the hepatic expression of the glucose-6-phosphatase and phosphoenolpyruvate carboxykinase genes in conscious rats.
Hyperglycemia
Carotid body denervation prevents fasting hyperglycemia during chronic intermittent hypoxia.
Hyperglycemia
Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production via elevated liver activating protein/liver inhibitory protein ratio.
Hyperglycemia
Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
Hyperglycemia
Effects of dieldrin on hepatic carbohydrate metabolism in the suckling and adult rat.
Hyperglycemia
ERK1/2 pathway is involved in renal gluconeogenesis inhibition under conditions of lowered NADPH oxidase activity.
Hyperglycemia
Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats.
Hyperglycemia
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes.
Hyperglycemia
Generation of fibroblasts overexpressing liver-specific PEPCK in a miniature pig model of human type 2 diabetes mellitus.
Hyperglycemia
Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway.
Hyperglycemia
Hepatic phosphoenolpyruvate carboxykinase expression after gastric bypass surgery in rats with type 2 diabetes mellitus.
Hyperglycemia
Histone Methylation of H3K4 Involved in the Anorexia of Carnivorous Mandarin Fish (Siniperca chuatsi) After Feeding on a Carbohydrate-Rich Diet.
Hyperglycemia
Hyperglycemia associated with increased hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase in rats following subchronic exposure to malathion.
Hyperglycemia
Impaired oxidative phosphorylation in hepatic mitochondria in growth-retarded rats.
Hyperglycemia
Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats.
Hyperglycemia
Liver-specific iNOS expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice.
Hyperglycemia
Liver-specific overexpression of pancreatic-derived factor (PANDER) induces fasting hyperglycemia in mice.
Hyperglycemia
Mechanisms by which bis(maltolato)oxovanadium(IV) normalizes phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression in streptozotocin-diabetic rats in vivo.
Hyperglycemia
Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation.
Hyperglycemia
Nicotinic acetylcholine receptors in glucose homeostasis: the acute hyperglycemic and chronic insulin-sensitive effects of nicotine suggest dual opposing roles of the receptors in male mice.
Hyperglycemia
Overcoming diabetes-induced hyperglycemia through inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP) with RNAi.
Hyperglycemia
Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.
Hyperglycemia
Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation.
Hyperglycemia
Paternal Psychological Stress Reprograms Hepatic Gluconeogenesis in Offspring.
Hyperglycemia
Phosphoenolpyruvate carboxykinase (GTP) gene transcription and hyperglycemia are regulated by glucocorticoids in genetically obese db/db transgenic mice.
Hyperglycemia
Phosphoenolpyruvate carboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in early insulin resistance and diabetes.
Hyperglycemia
Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity.
Hyperglycemia
Protection by pentoxifylline of diazinon-induced toxic stress in rat liver and muscle.
Hyperglycemia
Renal enzymes during experimental diabetes mellitus in the rat. Role of insulin, carbohydrate metabolism, and ketoacidosis.
Hyperglycemia
Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4.
Hyperglycemia
Specific reduction of G6PT may contribute to downregulation of hepatic 11?-HSD1 in diabetic mice.
Hyperglycemia
Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance.
Hyperglycemia
The effect of prolonged hyperglycemia on metabolic alterations in the subtotally pancreatectomized rat.
Hyperglycemia
The phosphorylation state of the cAMP response element binding protein is decreased in diabetic rat liver.
Hyperglycemia
The transcription factor CCAAT/enhancer-binding protein beta regulates gluconeogenesis and phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes.
Hyperglycemia
Transcription of hepatic cytosolic phosphoenolpyruvate carboxykinase gene in newborn dogs.
Hyperglycemia
Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice.
Hyperglycemia
Zhenqing recipe improves glucose metabolism and insulin sensitivity by repressing hepatic FOXO1 in type 2 diabetic rats.
Hyperhomocysteinemia
Hyperhomocysteinemia stimulates hepatic glucose output and PEPCK expression.
Hyperinsulinism
A new transgenic rat model of hepatic steatosis and the metabolic syndrome.
Hyperinsulinism
An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.
Hyperinsulinism
Changing pattern of prevalence of insulin resistance in Psammomys obesus, a model of nutritionally induced type 2 diabetes.
Hyperinsulinism
Chronic hyperinsulinemia in the fetal rhesus monkey: effects of physiologic hyperinsulinemia on fetal substrates, hormones, and hepatic enzymes.
Hyperinsulinism
Differential hepatic gene expression in a polygenic mouse model with insulin resistance and hyperglycemia: evidence for a combined transcriptional dysregulation of gluconeogenesis and fatty acid synthesis.
Hyperinsulinism
Down-regulation of hepatic phosphoenolpyruvate carboxykinase expression in magnesium-deficient rats.
Hyperinsulinism
Impaired glucose tolerance and increased weight gain in transgenic rats overexpressing a non-insulin-responsive phosphoenolpyruvate carboxykinase gene.
Hyperinsulinism
Inactivation of the adrenergic receptor ?2 disrupts glucose homeostasis in mice.
Hyperinsulinism
Increased insulin receptor substrate-1 and enhanced skeletal muscle insulin sensitivity in mice lacking CCAAT/enhancer-binding protein beta.
Hyperinsulinism
Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats.
Hyperinsulinism
Irreversibility of nutritionally induced NIDDM in Psammomys obesus is related to beta-cell apoptosis.
Hyperinsulinism
Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals.
Hyperinsulinism
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.
Hyperinsulinism
Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo R2.
Hyperinsulinism
Reciprocal changes in gluconeogenic enzyme activity in liver and kidney by VMH lesion.
Hyperinsulinism
Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance.
Hyperinsulinism
Transcription of hepatic cytosolic phosphoenolpyruvate carboxykinase gene in newborn dogs.
Hyperinsulinism
Vanillic acid mitigates the impairments in glucose metabolism in HepG2 cells through BAD-GK interaction during hyperinsulinemia.
Hyperlactatemia
Endotoxin induced hyperlactatemia and hypoglycemia is linked to decreased mitochondrial phosphoenolpyruvate carboxykinase.
Hyperlipidemias
Ergostatrien-3?-ol from Antrodia camphorata Inhibits Diabetes and Hyperlipidemia in High-Fat-Diet Treated Mice via Regulation of Hepatic Related Genes, Glucose Transporter 4, and AMP-Activated Protein Kinase Phosphorylation.
Hypersensitivity
Impairment of insulin-stimulated glucose transport and ERK activation by adipocyte-specific knockout of PKC-? produces a phenotype characterized by diminished adiposity and enhanced insulin suppression of hepatic gluconeogenesis.
Hypertension
Acute effect of whey peptides upon blood pressure of hypertensive rats, and relationship with their angiotensin-converting enzyme inhibitory activity.
Hypertension
Proximal tubular-targeted overexpression of the Cyp4a12-20-HETE synthase promotes salt-sensitive hypertension in male mice.
Hyperthyroidism
3,5,3'-Triiodothyronine-induced synthesis of rat liver phosphoenolpyruvate carboxykinase.
Hyperthyroidism
Cooperative effect of thyroid and glucocorticoid hormones on the induction of hepatic phosphoenolpyruvate carboxykinase in vivo and in cultured hepatocytes.
Hyperthyroidism
Effect of thyroid state on cyclic AMP-mediated induction of hepatic phosphoenolpyruvate carboxykinase.
Hyperthyroidism
Effects of hyperthyroidism on expression of a phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice.
Hyperthyroidism
Renal phosphoenolpyruvate carboxykinase turnover in hypo- and hyperthyroid rat in vivo.
Hyperthyroidism
Thyroid hormone regulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase (GTP) in rat liver.
Hypertriglyceridemia
A new transgenic rat model of hepatic steatosis and the metabolic syndrome.
Hypoglycemia
Carbohydrate metabolism in temporal and persistent hypoglycemic chickens induced by insulin infusion.
Hypoglycemia
Changing pattern of prevalence of insulin resistance in Psammomys obesus, a model of nutritionally induced type 2 diabetes.
Hypoglycemia
Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep.
Hypoglycemia
CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis.
Hypoglycemia
Cytosolic Phosphoenolpyruvate Carboxykinase Deficiency: Cause of Hypoglycemia-Induced Seizure and Death.
Hypoglycemia
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism.
Hypoglycemia
Differential effects of insulin-like growth factor-1 on neonatal canine gene expression.
Hypoglycemia
Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology.
Hypoglycemia
Endotoxin induced hyperlactatemia and hypoglycemia is linked to decreased mitochondrial phosphoenolpyruvate carboxykinase.
Hypoglycemia
Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPbeta gene.
Hypoglycemia
Hypoglycemia in the newborn growth-retarded rat: delayed phosphoenolpyruvate carboxykinase induction despite increased glucagon availability.
Hypoglycemia
In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice.
Hypoglycemia
Induction of cytosolic phosphoenolpyruvate carboxykinase in the ovine fetal liver by chronic fetal hypoglycemia and hypoinsulinemia.
Hypoglycemia
Influence of endotoxin treatment on dexamethasone induction of hepatic phosphoenolpyruvate carboxykinase.
Hypoglycemia
Novel homozygous PCK1 mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia, an abnormal pattern of urine metabolites and liver dysfunction.
Hypoglycemia
Novel missense variants in PCK1 gene cause cytosolic PEPCK deficiency with growth failure from inadequate caloric intake.
Hypoglycemia
Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha.
Hypoglycemia
PEPCK-C reexpression in the liver counters neonatal hypoglycemia in Pck1 (del/del) mice, unmasking role in non-gluconeogenic tissues.
Hypoglycemia
Postnatal profiles of glycogenolysis and gluconeogenesis are modified in rat pups by maternal dietary glucose restriction.
Hypoglycemia
Role of the isoforms of CCAAT/enhancer-binding protein in the initiation of phosphoenolpyruvate carboxykinase (GTP) gene transcription at birth.
Hypoglycemia
Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia.
Hypoglycemia
The reversal of increased gluconeogenesis in the tumor-bearing rat by tumor removal and food intake.
Hypoglycemia
The role of chicken ovalbumin upstream promoter transcription factor II in the regulation of hepatic fatty acid oxidation and gluconeogenesis in newborn mice.
Hypoglycemia
Upregulation of hepatic glucose 6-phosphatase gene expression in rats treated with an inhibitor of glucose-6-phosphate translocase.
Hypothyroidism
Cooperative effect of thyroid and glucocorticoid hormones on the induction of hepatic phosphoenolpyruvate carboxykinase in vivo and in cultured hepatocytes.
Infarction, Middle Cerebral Artery
Phosphoenolpyruvate Carboxykinase (PCK) in the Brain Gluconeogenic Pathway Contributes to Oxidative and Lactic Injury After Stroke.
Infections
Activities of key enzymes in the C4 pathway and anatomy of sugarcane infected by Leifsoniaxyli subsp. xyli.
Infections
Analyses of phosphoenolpyruvate carboxylase gene structure and expression in alfalfa nodules.
Infections
Differential patterns of liver proteins in experimental murine hepatosplenic schistosomiasis.
Infections
Dual specificity MAPK phosphatase 3 activates PEPCK gene transcription and increases gluconeogenesis in rat hepatoma cells.
Infections
Glucokinase expression in rat hepatoma cells induces glucose uptake and is rate limiting in glucose utilization.
Infections
Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection.
Infections
Hepatic gene transfer in animals using retroviruses containing the promoter from the gene for phosphoenolpyruvate carboxykinase.
Infections
Hormonal regulation of chimeric genes containing the phosphoenolpyruvate carboxykinase promoter regulatory region in hepatoma cells infected by murine retroviruses.
Infections
Increased Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression and Steatosis During Hepatitis C Virus (HCV) Subgenome Replication: Role of Nonstructural Component-5A (NS5A) and CCAAT/Enhancer Binding Protein ?(C/EBP?).
Infections
Inhibition of hepatic phosphoenolpyruvate carboxykinase by avian reticuloendotheliosis viruses.
Infections
Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway.
Infections
Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected by Anaplasma phagocytophilum Infection in Tick Cells.
Infections
Ionotropic Purinergic Receptors P2X4 and P2X7: Proviral or Antiviral? An Insight into P2X Receptor Signaling and Hepatitis C Virus Infection.
Infections
Link between Heterotrophic Carbon Fixation and Virulence in the Porcine Lung Pathogen Actinobacillus pleuropneumoniae.
Infections
pckA-deficient Mycobacterium bovis BCG shows attenuated virulence in mice and in macrophages.
Infections
Regulation of phosphoenolpyruvate carboxylase in PVY(NTN)-infected tobacco plants.
Infections
Structural and functional studies of phosphoenolpyruvate carboxykinase from Mycobacterium tuberculosis.
Infections
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.
Insulin Resistance
A potential probiotic bacterium for antipsychotic-induced metabolic syndrome: mechanisms underpinning how Akkermansia muciniphila subtype improves olanzapine-induced glucose homeostasis in mice.
Insulin Resistance
A primary defect in glucose production alone cannot induce glucose intolerance without defects in insulin secretion.
Insulin Resistance
Absence of melatonin induces night-time hepatic insulin resistance and increased gluconeogenesis due to stimulation of nocturnal unfolded protein response.
Insulin Resistance
Adipose overexpression of phosphoenolpyruvate carboxykinase leads to high susceptibility to diet-induced insulin resistance and obesity.
Insulin Resistance
Amelioration of glucose homeostasis by glycyrrhizic acid through gluconeogenesis rate-limiting enzymes.
Insulin Resistance
An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension.
Insulin Resistance
Anti-diabetic effects of new herbal formula in neonatally streptozotocin-induced diabetic rats.
Insulin Resistance
Arrestin domain-containing 3 (Arrdc3) modulates insulin action and glucose metabolism in liver.
Insulin Resistance
AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues.
Insulin Resistance
Beneficial effects of Aronia melanocarpa berry extract on hepatic insulin resistance in type 2 diabetes mellitus rats.
Insulin Resistance
Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis.
Insulin Resistance
Corticosterone-induced insulin resistance is not associated with alterations of insulin receptor number and kinase activity in chicken kidney.
Insulin Resistance
Dapagliflozin improves insulin resistance and glucose intolerance in a novel transgenic rat model of chronic glucose overproduction and glucose toxicity.
Insulin Resistance
Dynamic Behavior of Rat Phosphoenolpyruvate Carboxykinase Inhibitors: New Mechanism for Enzyme Inhibition.
Insulin Resistance
Effect of oxymatrine on liver gluconeogenesis is associated with the regulation of PEPCK and G6Pase expression and AKT phosphorylation.
Insulin Resistance
Effect of trivalent chromium on erythropoietin production and the prevention of insulin resistance in HepG2 cells.
Insulin Resistance
Effects of intravenous AICAR (5-aminoimidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp.
Insulin Resistance
Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice.
Insulin Resistance
Examination of the phosphoenolpyruvate carboxykinase gene promoter in patients with noninsulin-dependent diabetes mellitus.
Insulin Resistance
Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats.
Insulin Resistance
Expression of subcutaneous adipose tissue phosphoenolpyruvate carboxykinase correlates with body mass index in nondiabetic women.
Insulin Resistance
Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes.
Insulin Resistance
Gene-nutrient interactions on the phosphoenolpyruvate carboxykinase influence insulin sensitivity in metabolic syndrome subjects.
Insulin Resistance
Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis.
Insulin Resistance
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
Insulin Resistance
Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance.
Insulin Resistance
High-Efficacy ?,?-Dehydromonacolin S Improves Hepatic Steatosis and Suppresses Gluconeogenesis Pathway in High-Fat Diet-Induced Obese Rats.
Insulin Resistance
Hyperhomocysteinemia stimulates hepatic glucose output and PEPCK expression.
Insulin Resistance
Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis.
Insulin Resistance
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance.
Insulin Resistance
Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice.
Insulin Resistance
Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats.
Insulin Resistance
Increased nucleobindin-2 (NUCB2) transcriptional activity links the regulation of insulin sensitivity in type 2 diabetes mellitus.
Insulin Resistance
Increased Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression and Steatosis During Hepatitis C Virus (HCV) Subgenome Replication: Role of Nonstructural Component-5A (NS5A) and CCAAT/Enhancer Binding Protein ?(C/EBP?).
Insulin Resistance
Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance.
Insulin Resistance
Inhibition of NF-?B Reduces Renal Inflammation and Expression of PEPCK in Type 2 Diabetic Mice.
Insulin Resistance
Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats.
Insulin Resistance
Insulin resistance of gluconeogenic pathways in neonatal rats after prenatal ethanol exposure.
Insulin Resistance
Intermittent fasting reduces body fat but exacerbates hepatic insulin resistance in young rats regardless of high protein and fat diets.
Insulin Resistance
Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
Insulin Resistance
Irreversibility of nutritionally induced NIDDM in Psammomys obesus is related to beta-cell apoptosis.
Insulin Resistance
IRS-1/PI3K/Akt pathway and miRNAs are involved in whole grain highland barley (Hordeum vulgare L.) ameliorating hyperglycemia of db/db mice.
Insulin Resistance
Jerusalem artichoke and chungkookjang additively improve insulin secretion and sensitivity in diabetic rats.
Insulin Resistance
Kochujang, a Korean fermented red pepper plus soybean paste, improves glucose homeostasis in 90% pancreatectomized diabetic rats.
Insulin Resistance
Linkage analysis of 19 candidate regions for insulin resistance in familial NIDDM.
Insulin Resistance
Merit of physical exercise to reverse the higher gene expression of hepatic phosphoenolpyruvate carboxykinase in obese Zucker rats.
Insulin Resistance
Mibefradil reduces hepatic glucose output in HepG2 cells via Ca2+/calmodulin-dependent protein kinase II-dependent Akt/forkhead box O1signaling.
Insulin Resistance
MicroRNA-351 eases insulin resistance and liver gluconeogenesis via the PI3K/AKT pathway by inhibiting FLOT2 in mice of gestational diabetes mellitus.
Insulin Resistance
Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet.
Insulin Resistance
New approach in the treatment of T2DM and metabolic syndrome (focus on a novel insulin sensitizer).
Insulin Resistance
Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney.
Insulin Resistance
Phosphoenolpyruvate carboxykinase (Pck1) in hepatic and adipose tissue contributes to the regulation of the triglyceride fatty acid cycle and development of insulin resistance in mice.
Insulin Resistance
Phosphoenolpyruvate carboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in early insulin resistance and diabetes.
Insulin Resistance
Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice.
Insulin Resistance
Reduced Milk Triglycerides in Mice Lacking Phosphoenolpyruvate Carboxykinase in Mammary Gland Adipocytes and White Adipose Tissue Contribute to the Development of Insulin Resistance in Pups.
Insulin Resistance
Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet.
Insulin Resistance
Role of retinol-binding protein 4 in the pathogenesis of Type 2 diabetes.
Insulin Resistance
Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4.
Insulin Resistance
SIK1 Regulates CRTC2-Mediated Gluconeogenesis Signaling Pathway in Human and Mouse Liver Cells.
Insulin Resistance
Silencing of FGF-21 expression promotes hepatic gluconeogenesis and glycogenolysis by regulation of the STAT3-SOCS3 signal.
Insulin Resistance
Specific reduction of G6PT may contribute to downregulation of hepatic 11?-HSD1 in diabetic mice.
Insulin Resistance
TCTP participates in hepatic metabolism by regulating gene expression involved in insulin resistance.
Insulin Resistance
Telmisartan is effective to ameliorate metabolic syndrome in rat model - a preclinical report.
Insulin Resistance
The characteristics of hepatic Gs?-cAMP axis in HSHF diet-fed obese insulin resistance rats and genetic diabetic mice.
Insulin Resistance
Transcription factor TIP27 regulates glucose homeostasis and insulin sensitivity in a PI3-kinase/Akt-dependent manner in mice.
Insulin Resistance
Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.
Insulin Resistance
Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes.
Insulin Resistance
Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats.
Insulin Resistance
Zingiber mioga reduces weight gain, insulin resistance and hepatic gluconeogenesis in diet-induced obese mice.
Insulin Resistance
[Effect of intrauterine growth retardation on gluconeogenic enzymes in rat liver].
Insulin Resistance
[Effects of Astragalus membranaceus and Potentilla discolor mixture on insulin resistance and its related mRNA expressions in KKAy mice with type 2 diabetes].
Insulin Resistance
[Increased expression of gluconeogenic enzymes in the liver of IUGR rats and subsequent insulin resistance]
Insulin Resistance
[Relationship between adipose phosphoenolpyruvate carboxykinase and occurrence and reversion of insulin resistance]
Intestinal Volvulus
Phosphoenolpyruvate carboxykinase from Onchocerca volvulus and O. gibsoni.
Iron Deficiencies
Metabolic changes of iron uptake in N(2)-fixing common bean nodules during iron deficiency.
Iron Deficiencies
Metabolic changes of iron uptake in N?-fixing common bean nodules during iron deficiency
Iron Deficiencies
Metabolic response in roots of Prunus rootstocks submitted to iron chlorosis.
Iron Deficiencies
Phosphoenolpyruvate carboxylase in cucumber (Cucumis sativus L.) roots under iron deficiency: activity and kinetic characterization.
Ketosis
Effect of insulin-like growth factor-1 (IGF-1) on the gluconeogenesis in calf hepatocytes cultured in vitro.
Ketosis
Regulation of messenger ribonucleic acid expression for gluconeogenic enzymes during glucagon infusions into lactating cows.
Ketosis
Renal enzymes during experimental diabetes mellitus in the rat. Role of insulin, carbohydrate metabolism, and ketoacidosis.
Leishmaniasis
Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4+ T cells.
Leprosy
Intracellular Mycobacterium leprae Utilizes Host Glucose as a Carbon Source in Schwann Cells.
Leukemia
Lithium inhibits hepatic gluconeogenesis and phosphoenolpyruvate carboxykinase gene expression.
Leukemia
Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes.
Leukemia
Vanadate inhibits expression of the gene for phosphoenolpyruvate carboxykinase (GTP) in rat hepatoma cells.
Liver Diseases
Novel homozygous PCK1 mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia, an abnormal pattern of urine metabolites and liver dysfunction.
Liver Diseases
Stimulation of rat kidney phosphoenolpyruvate carboxykinase activity in experimental liver disease induced by galactosamine.
Liver Diseases
The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression.
Liver Failure
Cytosolic phosphoenolpyruvate carboxykinase deficiency presenting with acute liver failure following gastroenteritis.
Liver Failure
Novel missense variants in PCK1 gene cause cytosolic PEPCK deficiency with growth failure from inadequate caloric intake.
Liver Failure, Acute
Cytosolic phosphoenolpyruvate carboxykinase deficiency presenting with acute liver failure following gastroenteritis.
Liver Failure, Acute
[The effect of endotoxemia on gluconeogenesis in livers and kidneys during acute hepatic failure.]
Liver Neoplasms
Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma.
Liver Neoplasms
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Lung Neoplasms
Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer.
Lung Neoplasms
PCK2 activation mediates an adaptive response to glucose depletion in lung cancer.
Lymphopenia
Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism.
Magnesium Deficiency
Down-regulation of hepatic phosphoenolpyruvate carboxykinase expression in magnesium-deficient rats.
Magnesium Deficiency
Hepatic gluconeogenic enzymes, plasma insulin and glucagon response to magnesium deficiency and fasting.
Malaria
Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase.
Marek Disease
Genetic variability of the cytosolic phosphoenolpyruvate carboxykinase gene in white leghorn chickens.
Marek Disease
Mitochondrial PEPCK: a highly polymorphic gene with alleles co-selected with Marek's disease resistance in chickens.
Melanoma
Upregulation of cytosolic phosphoenolpyruvate carboxykinase is a critical metabolic event in melanoma cells that repopulate tumors.
Metabolic Diseases
Lactobacillus acidophilus NS1 Reduces Phosphoenolpyruvate Carboxylase Expression by Regulating HNF4? Transcriptional Activity.
Metabolic Syndrome
A new transgenic rat model of hepatic steatosis and the metabolic syndrome.
Metabolic Syndrome
Amelioration of glucose homeostasis by glycyrrhizic acid through gluconeogenesis rate-limiting enzymes.
Metabolic Syndrome
Antiresistin RNA Oligonucleotide Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease in Mice through Attenuating Proinflammatory Cytokines.
Metabolic Syndrome
Gene-nutrient interactions on the phosphoenolpyruvate carboxykinase influence insulin sensitivity in metabolic syndrome subjects.
Metabolic Syndrome
Impaired Cavernous Reinnervation after Penile Nerve Injury in Rats with Features of the Metabolic Syndrome.
Metabolic Syndrome
Liver upregulation of genes involved in cortisol production and action is associated with metabolic syndrome in morbidly obese patients.
Metabolic Syndrome
Proposed involvement of adipocyte glyceroneogenesis and phosphoenolpyruvate carboxykinase in the metabolic syndrome.
Neoplasm Metastasis
Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer.
Neoplasm Metastasis
High Expression of PQBP1 and Low Expression of PCK2 are Associated with Metastasis and Recurrence of Osteosarcoma and Unfavorable Survival Outcomes of the Patients.
Neoplasms
A newly discovered role of metabolic enzyme PCK1 as a protein kinase to promote cancer lipogenesis.
Neoplasms
Anti-diabetic potential of alkaloid rich fraction from Capparis decidua on diabetic mice.
Neoplasms
Bcl-2 inhibits tumor necrosis factor-alpha-mediated increase of glycolytic enzyme activities and enhances pyruvate carboxylase activity.
Neoplasms
Biochemical evidence on the potential role of organophosphates in hepatic glucose metabolism toward insulin resistance through inflammatory signaling and free radical pathways.
Neoplasms
Computational evaluation of natural compounds as potential inhibitors of human PEPCK-M: an alternative for lung cancer therapy.
Neoplasms
Distinction of seventy-one cultured human tumor cell lines by polymorphic enzyme analysis.
Neoplasms
Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer.
Neoplasms
Down-regulation of the phosphoenolpyruvate carboxykinase gene in human colon tumors and induction by omega-3 fatty acids.
Neoplasms
Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma.
Neoplasms
Effect of dexamethasone on NF-kB activation, tumor necrosis factor formation, and glucose dyshomeostasis in septic rats.
Neoplasms
Erythropoietin inhibits gluconeogenesis and inflammation in the liver and improves glucose intolerance in high-fat diet-fed mice.
Neoplasms
Expression of two androgen-induced proteins (pepsinogen C and apolipoprotein d) in epithelial skin cancers of the eyelids.
Neoplasms
Extended culturing of androgen-responsive human primary epithelial prostate cell isolates by continuous treatment with interstitial collagenase.
Neoplasms
Gluconeogenesis in cancer cells - Repurposing of a starvation-induced metabolic pathway?
Neoplasms
Identification of tumor necrosis factor as a transcriptional regulator of the phosphoenolpyruvate carboxykinase gene following endotoxin treatment of mice.
Neoplasms
Immunoenzymatically determined pepsinogen C concentration in breast tumor cytosols: an independent favorable prognostic factor in node-positive patients.
Neoplasms
Impairment by interleukin 1 beta and tumour necrosis factor alpha of the glucagon-induced increase in phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis in cultured rat hepatocytes.
Neoplasms
Inhibition of gluconeogenesis at the phosphoenolpyruvate carboxykinase and pyruvate carboxylase reactions, as a means of cancer chemotherapy.
Neoplasms
Inhibition of hepatic phosphoenolpyruvate carboxykinase by avian reticuloendotheliosis viruses.
Neoplasms
Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer.
Neoplasms
Integration of transcriptomic data and metabolic networks in cancer samples reveals highly significant prognostic power.
Neoplasms
Intricate Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Isoforms in Normal Physiology and Disease.
Neoplasms
Liver inflammation and metabolic signaling in ApcMin/+ mice: the role of cachexia progression.
Neoplasms
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability.
Neoplasms
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.
Neoplasms
Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha.
Neoplasms
On the influence of overexpression of phosphoenolpyruvate carboxykinase in Streptomyces lividans on growth and production of human tumour necrosis factor-alpha.
Neoplasms
PCK1 Downregulation Promotes TXNRD1 Expression and Hepatoma Cell Growth via the Nrf2/Keap1 Pathway.
Neoplasms
PCK2 opposes mitochondrial respiration and maintains the redox balance in starved lung cancer cells.
Neoplasms
PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth.
Neoplasms
Phosphoenolpyruvate Carboxykinase Maintains Glycolysis-driven Growth in Drosophila Tumors.
Neoplasms
Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca2.
Neoplasms
Phytomodulatory proteins promote inhibition of hepatic glucose production and favor glycemic control via the AMPK pathway.
Neoplasms
Stat3-mediated activation of miR-23a suppresses gluconeogenesis in hepatocellular carcinoma by downregulating G6PC and PGC-1?
Neoplasms
The effects of a biological response modifier, OK-432, on tumor-induced alterations in the host metabolism.
Neoplasms
The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
Neoplasms
The reversal of increased gluconeogenesis in the tumor-bearing rat by tumor removal and food intake.
Neoplasms
The transcriptomic responses of the ark shell, Anadara broughtonii, to sulfide and hypoxia exposure.
Neoplasms
Transcriptome sequencing identifies genes associated with invasion of ovarian cancer.
Neoplasms
Tumor-associated metabolic alterations in patients with gastric and esophageal cancer.
Neoplasms
Tumorigenicity of simian virus 40-hepatocyte cell lines: effect of in vitro and in vivo passage on expression of liver-specific genes and oncogenes.
Neoplasms
Tumour necrosis factor-alpha attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells.
Neoplasms
Upregulation of cytosolic phosphoenolpyruvate carboxykinase is a critical metabolic event in melanoma cells that repopulate tumors.
Neuroectodermal Tumors, Primitive
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors.
Neuroendocrine Tumors
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors.
Non-alcoholic Fatty Liver Disease
Adiponectin is required for pioglitazone-induced improvements in hepatic steatosis in mice fed a high-fat diet.
Non-alcoholic Fatty Liver Disease
Antiresistin RNA Oligonucleotide Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease in Mice through Attenuating Proinflammatory Cytokines.
Non-alcoholic Fatty Liver Disease
Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis.
Obesity
Adipose overexpression of phosphoenolpyruvate carboxykinase leads to high susceptibility to diet-induced insulin resistance and obesity.
Obesity
Association of PCK1 with Body Mass Index and Other Metabolic Features in Patients With Psychotropic Treatments.
Obesity
Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a.
Obesity
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance.
Obesity
Liver upregulation of genes involved in cortisol production and action is associated with metabolic syndrome in morbidly obese patients.
Obesity
[Effects of expression of fatty acid synthetase and phosphoenolpyruvate carboxykinase in offspring rats by high protein intake in pregnancy]
Obesity, Abdominal
Effect and the probable mechanisms of silibinin in regulating insulin resistance in the liver of rats with non-alcoholic fatty liver.
Obesity, Morbid
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Overnutrition
Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver.
Paralysis
?-Viniferin and resveratrol induced alteration in the activities of some energy metabolism related enzymes in the cestode parasite Raillietina echinobothrida.
Paralysis
Anthelmintic efficacy of Flemingia vestita (Fabaceae): alteration in the activities of some glycolytic enzymes in the cestode, Raillietina echinobothrida.
Peritonitis
Altered levels of mRNA encoding enzymes of hepatic glucose metabolism in septic rats.
Peritonitis
Efficacy of anti-tumor necrosis factor polyclonal antibody on phosphoenolpyruvate carboxykinase expression in septic and endotoxemic rats.
phosphoenolpyruvate carboxylase deficiency
Cloning, purification, and properties of a cofactor-independent glutamate racemase from Lactobacillus brevis ATCC 8287.
phosphoenolpyruvate carboxylase deficiency
Cytosolic phosphoenolpyruvate carboxykinase deficiency presenting with acute liver failure following gastroenteritis.
phosphoenolpyruvate carboxylase deficiency
Cytosolic Phosphoenolpyruvate Carboxykinase Deficiency: Cause of Hypoglycemia-Induced Seizure and Death.
phosphoenolpyruvate carboxylase deficiency
Hepatic phosphoenolpyruvate carboxykinase deficiency: a neonatal case with reduced activity of pyruvate carboxylase.
phosphoenolpyruvate carboxylase deficiency
Mitochondrial phosphoenolpyruvate carboxykinase deficiency.
phosphoenolpyruvate carboxylase deficiency
Novel homozygous PCK1 mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia, an abnormal pattern of urine metabolites and liver dysfunction.
phosphoenolpyruvate carboxylase deficiency
Novel missense variants in PCK1 gene cause cytosolic PEPCK deficiency with growth failure from inadequate caloric intake.
phosphoenolpyruvate carboxylase deficiency
The genetic heterogeneity of lactic acidosis: occurrence of recognizable inborn errors of metabolism in pediatric population with lactic acidosis.
phosphoenolpyruvate carboxylase deficiency
Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity.
phosphoenolpyruvate carboxylase deficiency
Two cases of phosphoenolpyruvate carboxykinase deficiency.
Porphyria, Acute Intermittent
How porphyrinogenic drugs modeling acute porphyria impair the hormonal status that regulates glucose metabolism. Their relevance in the onset of this disease.
Porphyrias
Hexachlorobenzene as hormonal disruptor--studies about glucocorticoids: their hepatic receptors, adrenal synthesis and plasma levels in relation to impaired gluconeogenesis.
Porphyrias, Hepatic
Response of glucose metabolism enzymes in an acute porphyria model. Role of reactive oxygen species.
Prediabetic State
Phosphoenolpyruvate carboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in early insulin resistance and diabetes.
Prostatic Neoplasms
Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells.
protein-tyrosine-phosphatase deficiency
Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance.
pyruvate carboxylase deficiency
Pyruvate carboxylase and phosphoenolpyruvate carboxykinase activity in leukocytes and fibroblasts from a patient with pyruvate carboxylase deficiency.
Pyruvate Carboxylase Deficiency Disease
Pyruvate carboxylase and phosphoenolpyruvate carboxykinase activity in leukocytes and fibroblasts from a patient with pyruvate carboxylase deficiency.
Reticuloendotheliosis, Avian
Inhibition of hepatic phosphoenolpyruvate carboxykinase by avian reticuloendotheliosis viruses.
Retinoblastoma
Adenovirus E1A proteins regulate phosphoenolpyruvate carboxykinase gene transcription through multiple mechanisms.
Sarcoma
Sheep gene mapping: additional DNA markers included (CASB, CASK, LALBA, IGF-1 and AMH).
Sarcoma
The reversal of increased gluconeogenesis in the tumor-bearing rat by tumor removal and food intake.
Seizures
Cytosolic Phosphoenolpyruvate Carboxykinase Deficiency: Cause of Hypoglycemia-Induced Seizure and Death.
Sepsis
Altered levels of mRNA encoding enzymes of hepatic glucose metabolism in septic rats.
Sepsis
Berberine reduces gut-vascular barrier permeability via modulation of ApoM/S1P pathway in a model of polymicrobial sepsis.
Sepsis
Effect of dexamethasone on NF-kB activation, tumor necrosis factor formation, and glucose dyshomeostasis in septic rats.
Sepsis
Efficacy of anti-tumor necrosis factor polyclonal antibody on phosphoenolpyruvate carboxykinase expression in septic and endotoxemic rats.
Sepsis
Endotoxin causes reciprocal changes in hepatic nitric oxide synthesis, gluconeogenesis, and flux through phosphoenolpyruvate carboxykinase.
Sepsis
Hepatic gene expression and cytokine responses to sterile inflammation: comparison with cecal ligation and puncture sepsis in the rat.
Sepsis
In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice.
Sepsis
Sepsis-induced alterations in phosphoenolpyruvate carboxykinase expression: the role of insulin and glucagon.
Shock, Septic
Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha.
Shock, Septic
The effect of iNOS deletion on hepatic gluconeogenesis in hyperdynamic murine septic shock.
Sleep Deprivation
Peripheral and central blockade of interleukin-6 trans-signaling differentially affects sleep architecture.
Smith-Magenis Syndrome
Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity.
Starvation
11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress.
Starvation
3,5,3'-Triiodothyronine-induced synthesis of rat liver phosphoenolpyruvate carboxykinase.
Starvation
A selective autophagy pathway that degrades gluconeogenic enzymes during catabolite inactivation.
Starvation
Age-dependent glycolysis and gluconeogenesis enzyme activities in starved-refed rats.
Starvation
Appropriate leucine supplementation promotes glucose metabolism and enhances energy homeostasis in juvenile crucian carp (Carassius auratus gibelio var. CAS III).
Starvation
Avian phosphoenolpyruvate carboxykinase: effect of age, starvation and photoperiod.
Starvation
BHLH32 modulates several biochemical and morphological processes that respond to Pi starvation in Arabidopsis.
Starvation
Changes in rat hepatic fructose 2,6-bisphosphate and 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase activity during three days of consumption of a high protein diet or starvation.
Starvation
Characterization and functional analysis of phosphoenolpyruvate carboxylase kinase genes in rice.
Starvation
Comparison between starvation and consumption of a high protein diet: plasma insulin and glucagon and hepatic activities of gluconeogenic enzymes during the first 24 hours.
Starvation
Detection and hormonal regulation of the mRNA for cytosolic phosphoenolpyruvate carboxykinase in rat lung.
Starvation
Distribution along the rat nephron of three enzymes of gluconeogenesis in acidosis and starvation.
Starvation
Effect of cold exposure on phosphoenolpyruvate carboxykinase (GTP) activity and cyclic amp concentration in livers of starved rats. Role of glucorticoids.
Starvation
Effect of hibernation on liver and kidney metabolism in 13-lined ground squirrels.
Starvation
Effect of hormones on transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase (GTP) in rat kidney.
Starvation
Effects of nutrition and ontogeny on liver cytosolic and mitochondrial phosphoenolpyruvate carboxykinase activity of the rat, hamster, guinea-pig, pig, kid, calf and chick.
Starvation
Effects of starvation and refeeding a high carbohydrate diet on the intra-acinar distribution pattern of phosphoenolpyruvate carboxykinase activity in the liver of male and female rats.
Starvation
Glucose deprivation induced upregulation of phosphoenolpyruvate carboxykinase modulates virulence in Leishmania donovani.
Starvation
Hormonal and nutritional regulation of phosphoenolpyruvate carboxykinase mRNA levels in chicken kidney.
Starvation
Induction of rat liver phosphoenolpyruvate carbonxykinase (GTP) by cyclic AMP during starvation. The permissive action of glucocorticoids.
Starvation
Intricate Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Isoforms in Normal Physiology and Disease.
Starvation
Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation.
Starvation
Metabolic adaptation of the renal carbohydrate metabolism. I. Effects of starvation on the gluconeogenic and glycolytic fluxes in the proximal and distal renal tubules.
Starvation
Metabolic responses in cucumber (Cucumis sativus L.) roots under Fe-deficiency: a 31P-nuclear magnetic resonance in-vivo study.
Starvation
On the mechanism of gluconeogenesis and its regulation. 3. The glucogenic capacity and the activities of pyruvate carboxylase and PEP-carboxylase of rat kidney and rat liver after cortisol treatment and starvation.
Starvation
Phosphate Starvation Inducible ;Bypasses' of Adenylate and Phosphate Dependent Glycolytic Enzymes in Brassica nigra Suspension Cells.
Starvation
Phosphoenolpyruvate carboxykinase in mouse pancreatic islets. ATP-induced changes in sensitivity to Mn2+ activation.
Starvation
Phosphoenolpyruvate carboxykinase of rat small intestine: distribution and regulation of activity and mRNA levels.
Starvation
Phosphoenolpyruvate carboxylase (PEPC) and PEPC-kinase (PEPC-k) isoenzymes in Arabidopsis thaliana: role in control and abiotic stress conditions.
Starvation
Phosphoenolpyruvate carboxylase in cucumber (Cucumis sativus L.) roots under iron deficiency: activity and kinetic characterization.
Starvation
Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca2.
Starvation
Purification and characterization of phosphoenolpyruvate carboxylase from Brassica napus (rapeseed) suspension cell cultures: implications for phosphoenolpyruvate carboxylase regulation during phosphate starvation, and the integration of glycolysis with nitrogen assimilation.
Starvation
Rapid changes in the concentration of phosphoenolpyruvate carboxykinase mRNA in rat liver and kidney. Effects of insulin and cyclic AMP.
Starvation
Role of small leucine zipper protein in hepatic gluconeogenesis and metabolic disorder.
Starvation
Subcellular location of phosphoenolpyruvate carboxykinase in hepatocytes from fed and starved rats.
Starvation
Sugar-Starvation-Induced Changes of Carbon Metabolism in Excised Maize Root Tips.
Starvation
Synthesis and degradation of phosphoenolpyruvate carboxylase in rat liver and adipose tissue. Changes during a starvation-re-feeding cycle.
Starvation
The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism.
Starvation
Transcriptional and Posttranscriptional Regulation of Nitrogen-Responding Expression of Phosphoenolpyruvate Carboxylase Gene in Maize.
Starvation
Two isoforms of Pepck in Sarcophaga bullata and their distinct expression profiles through development, diapause, and in response to stresses of cold and starvation.
Starvation
Vanadate normalizes hyperglycemia and phosphoenolpyruvate carboxykinase mRNA levels in ob/ob mice.
Stomach Neoplasms
Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis.
Stroke
Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia.
Stroke
Phosphoenolpyruvate Carboxykinase (PCK) in the Brain Gluconeogenic Pathway Contributes to Oxidative and Lactic Injury After Stroke.
Tics
Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells.
Tuberculosis
Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.
Tuberculosis
Methylotrophy in Mycobacteria: Dissection of the Methanol Metabolism Pathway in Mycobacterium smegmatis.
Tuberculosis
Modulation of Central Carbon Metabolism by Acetylation of Isocitrate Lyase in Mycobacterium tuberculosis.
Tuberculosis
Mycobacterium Tuberculosis Phosphoenolpyruvate Carboxykinase is Regulated by Redox Mechanisms and Interaction with Thioredoxin.
Tuberculosis
Production of avirulent mutants of Mycobacterium bovis with vaccine properties by the use of illegitimate recombination and screening of stationary-phase cultures.
Tuberculosis
Structural and functional studies of phosphoenolpyruvate carboxykinase from Mycobacterium tuberculosis.
Tuberculosis
The phosphoenolpyruvate carboxykinase of mycobacterium tuberculosis induces strong cell-mediated immune responses in mice.
Tuberculosis
The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis.
Tuberculosis
[Recombinant phosphoenolpyruvate carboxykinase from Mycobacterium tuberculosis for sero diagnosis]
Tuberous Sclerosis
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
Virus Diseases
A systems medicine approach reveals disordered immune system and lipid metabolism in multiple sclerosis patients.
Virus Diseases
Expression of phosphoenolpyruvate carboxykinase (PEPCK) chimeras in renal epithelial cells. Retention of appropriate physiological responsiveness using enhancerless retroviral vectors.
Virus Diseases
Inhibition of hepatic phosphoenolpyruvate carboxykinase by avian reticuloendotheliosis viruses.
Virus Diseases
Regulation of phosphoenolpyruvate carboxylase in PVY(NTN)-infected tobacco plants.
Vitamin A Deficiency
Effects of vitamin A deficiency and retinoic acid treatment on expression of a phosphoenolpyruvate carboxykinase-bovine growth hormone gene in transgenic mice.
Vitamin A Deficiency
Nuclear receptor binding to the retinoic acid response elements of the phosphoenolpyruvate carboxykinase gene in vivo: effects of vitamin A deficiency.
Vitamin A Deficiency
Retinoid regulation of the phosphoenolpyruvate carboxykinase gene in liver.
Vitamin A Deficiency
RNA polymerase II association with the phosphoenolpyruvate carboxykinase (PEPCK) promoter is reduced in vitamin A-deficient mice.
Vitamin A Deficiency
Vitamin A regulates genes involved in hepatic gluconeogenesis in mice: phosphoenolpyruvate carboxykinase, fructose-1,6-bisphosphatase and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Vitamin A Deficiency
Vitamin A status in mice affects the histone code of the phosphoenolpyruvate carboxykinase gene in liver.
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