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Disease on EC 4.1.1.19 - arginine decarboxylase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Brain Edema
Endogenous Agmatine Induced by Ischemic Preconditioning Regulates Ischemic Tolerance Following Cerebral Ischemia.
Chagas Disease
Inhibition of ornithine or arginine decarboxylase as an experimental approach to African or American trypanosomiasis.
Trypanosoma cruzi as a model system to study the expression of exogenous genes coding for polyamine biosynthetic enzymes. Induction of DFMO resistance in transgenic parasites.
Dehydration
An arginine decarboxylase gene PtADC from Poncirus trifoliata confers abiotic stress tolerance and promotes primary root growth in Arabidopsis.
Involvement of polyamines in the drought resistance of rice.
Molecular cloning and expression analysis of an arginine decarboxylase gene from peach (Prunus persica).
Overexpression of a stress-responsive MYB transcription factor of Poncirus trifoliata confers enhanced dehydration tolerance and increases polyamine biosynthesis.
Overexpression of PtADC confers enhanced dehydration and drought tolerance in transgenic tobacco and tomato: Effect on ROS elimination.
Infections
Apoplastic polyamine oxidation plays different roles in local responses of tobacco to infection by the necrotrophic fungus Sclerotinia sclerotiorum and the biotrophic bacterium Pseudomonas viridiflava.
Engineered polyamine catabolism preinduces tolerance of tobacco to bacteria and oomycetes.
Group A streptococci from invasive-disease episodes in Poland are remarkably divergent at the molecular level.
Polyamine metabolism in flax in response to treatment with pathogenic and non-pathogenic Fusarium strains.
Malaria
Peripheral blood mononuclear cell transcriptomes reveal an over-representation of down-regulated genes associated with immunity in HIV-exposed uninfected infants.
Mania
Evaluation of plasma agmatine level and its metabolic pathway in patients with bipolar disorder during manic episode and remission period.
Mycoses
Protection of wheat against leaf and stem rust and powdery mildew diseases by inhibition of polyamine metabolism.
Neoplasms
Arginine and nutrition in renal disease.
Arginine depriving enzymes: applications as emerging therapeutics in cancer treatment.
Neurodegenerative Diseases
Agmatine reverses memory deficits induced by A?1-42 peptide in mice: A key role of imidazoline receptors.
Potassium Deficiency
Polyamine Metabolism in Scots Pine Embryogenic Cells under Potassium Deficiency.
Regulation of Arabidopsis thaliana (L.) Heynh Arginine decarboxylase by potassium deficiency stress.
Seizures
Anticonvulsive effect of agmatine in mice.
Sexually Transmitted Diseases
Structure-based drug target prioritisation and rational drug design for targeting Chlamydia trachomatis eye infections.
Spinal Cord Injuries
Restorative benefits of transplanting human mesenchymal stromal cells overexpressing arginine decarboxylase genes after spinal cord injury.
Trauma, Nervous System
The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells.