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Information on EC 4.1.1.17 - ornithine decarboxylase
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4.1.1.17 ornithine decarboxylaseIUBMB Comments
A pyridoxal-phosphate protein.
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Word Map
- 4.1.1.17
- polyamine
- spermidine
- alpha-difluoromethylornithine
- carcinogenesis
- antizyme
-
chemopreventive
- 12-o-tetradecanoylphorbol-13-acetate
-
phorbol
- mucosa
- difluoromethylornithine
-
diamine
- decarboxylases
-
n1-acetyltransferase
- hyperplasia
- arginase
- c-myc
-
antiproliferative
-
tpa-induced
- prostaglandin
- testosterone
-
3hthymidine
- tumorigenesis
-
mitogen
- cycloheximide
- c-fos
- methylglyoxal
-
tpa-treated
- 1,2-dimethylhydrazine
- isoproterenol
- hairless
- degrons
-
12-o-tetradecanoyl
-
hepatectomy
- cadaverine
- s-adenosyl-l-methionine
- drug development
- azoxymethane
-
protooncogene
- papilloma
-
7,12-dimethylbenzaanthracene
- agmatine
- phorbol-13-acetate
- medicine
-
tumor-promoting
- food industry
- diagnostics
- nitrilotriacetate
- pharmacology
- prolactin
-
crypt
- trypanothione
-
12-o-tetradecanoylphorbol
-
ester-induced
- actinomycin
- mezerein
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
odc, ornithine decarboxylase, ldodc, lysine/ornithine decarboxylase, s-adenosylmethionine decarboxylase/ornithine decarboxylase, ldc/odc, odc-paralogue, xodc2, adometdc/odc, ddodc, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
bODC
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-
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Decarboxylase, ornithine
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-
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ODC
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-
-
-
ODC-paralogue
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XODC1
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-
-
-
XODC2
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-
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
decarboxylation
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-
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-
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PATHWAY SOURCE
PATHWAYS
BRENDA
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-, -
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SYSTEMATIC NAME
IUBMB Comments
L-ornithine carboxy-lyase (putrescine-forming)
A pyridoxal-phosphate protein.
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CAS REGISTRY NUMBER
COMMENTARY
9024-60-6
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Aberrant Crypt Foci
Chemoprevention of azoxymethane-induced intestinal carcinogenesis by a novel synthesized retinoidal butenolide, 5-hydroxy-4-(2-phenyl-(E)-ethenyl)-2(5H)-furanone, in rats.
Aberrant Crypt Foci
Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models.
Aberrant Crypt Foci
Effect of grape seed proanthocyanidins on colon aberrant crypts and breast tumors in a rat dual-organ tumor model.
Aberrant Crypt Foci
Ellagic acid modulates antioxidant status, ornithine decarboxylase expression, and aberrant crypt foci progression in 1,2-dimethylhydrazine-instigated colon preneoplastic lesions in rats.
Aberrant Crypt Foci
Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon.
Aberrant Crypt Foci
Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon.
Aberrant Crypt Foci
Suppression of chemical carcinogenesis by water-soluble organosulfur compounds.
Abortion, Habitual
TAAR1 induces a disturbed GSK3? phosphorylation in recurrent miscarriages through the ODC.
Acidosis
Effect of variations in blood hydrogen ion concentration on pulmonary gas exchange of artificially ventilated dogs.
Acidosis, Respiratory
[Hemoglobin oxygen transport during experimental acute hypercapnia (author's transl)]
Acquired Immunodeficiency Syndrome
High-pressure liquid chromatographic analysis of eflornithine in serum.
Acquired Immunodeficiency Syndrome
Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-alpha-difluoromethylornithine.
Acute Kidney Injury
Regenerative response in acute renal failure due to vitamin E deficiency and glutathione depletion in rats.
Acute Kidney Injury
Thyroid hormone induction of ornithine decarboxylase in ischemic acute renal failure.
Adenocarcinoma
A comparison of ornithine decarboxylase and S-adenosylmethionine decarboxylase activity in human large bowel mucosa, polyps, and colorectal adenocarcinoma.
Adenocarcinoma
Chemoprevention of prostate carcinogenesis by DFMO and/or finasteride treatment in male Wistar rats.
Adenocarcinoma
Chemopreventive effect of protein extract of Asterina pectinifera in HT-29 human colon adenocarcinoma cells.
Adenocarcinoma
Chemosensitization of cultured human carcinoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by difluoromethylornithine-induced polyamine depletion.
Adenocarcinoma
Colorectal ornithine decarboxylase activity in human mucosa and tumors: elevation of enzymatic activity in distal mucosa.
Adenocarcinoma
Difluoromethylornithine antagonizes taxol cytotoxicity in MCF-7 human breast cancer cells.
Adenocarcinoma
Effects of cyclosporin A and alpha-difluoromethylornithine on the growth of hamster pancreatic cancer in vitro.
Adenocarcinoma
Effects of DFMO-induced polyamine depletion on human tumor cell sensitivity to antineoplastic DNA-crosslinking drugs.
Adenocarcinoma
Effects of difluoromethylornithine on proliferation, polyamine content and plating efficiency of cultured human carcinoma cells.
Adenocarcinoma
Increased mucosal ornithine decarboxylase activity in large bowel with multiple tumors, adenocarcinoma, and adenoma.
Adenocarcinoma
Induction of ornithine decarboxylase by sialagogues in a human parotid gland adenocarcinoma cell line.
Adenocarcinoma
Inhibitory effects of a calcium antagonist on ornithine decarboxylase induction in pancreatic cancer cell lines.
Adenocarcinoma
Isolation and characterization of human breast adenocarcinoma cells made resistant to alpha-difluoromethylornithine.
Adenocarcinoma
L-arginine reduces cell proliferation and ornithine decarboxylase activity in patients with colorectal adenoma and adenocarcinoma.
Adenocarcinoma
Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer.
Adenocarcinoma
Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites.
Adenocarcinoma
Ornithine decarboxylase activity and polyamine content in adenocarcinomas of human stomach and large intestine.
Adenocarcinoma
Ornithine decarboxylase activity in human endometrium and endometrial cancer cells.
Adenocarcinoma
Ornithine decarboxylase and glutamate decarboxylase 65 as prognostic markers of gallbladder malignancy: a clinicopathological study in benign and malignant lesions of the gallbladder.
Adenocarcinoma
Polyamine biosynthetic activity in normal and neoplastic human colorectal tissues.
Adenocarcinoma
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade.
Adenocarcinoma
Potentiation of methylglyoxal-bis-guanylhydrazone by alpha-difluoromethylornithine in rat prostate cancer.
Adenocarcinoma
PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity.
Adenocarcinoma
Premalignant alterations in rat colonic N1-acetylspermidine levels induced by 1,2-dimethylhydrazine: effects of a high corn oil dietary regimen.
Adenocarcinoma
Prognostic significance of ornithine decarboxylase (ODC) activity in endometrial adenocarcinoma.
Adenocarcinoma
Reduced cytocidal efficacy for adriamycin in cultured human carcinoma cells depleted of polyamines by difluoromethylornithine treatment.
Adenocarcinoma
Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.
Adenocarcinoma
The growth of MAT-LyLu rat prostatic adenocarcinoma can be prevented in vivo by polyamine deprivation.
Adenocarcinoma
Transcriptional gene expression profiles of oesophageal adenocarcinoma and normal oesophageal tissues.
Adenocarcinoma
Upregulation of ornithine decarboxylase mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma.
Adenocarcinoma
ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression.
Adenocarcinoma
[Gene expression profiling of human ovarian epithelial tumors by digo nucleotide microarray]
Adenocarcinoma
[Ornithine decarboxylase activity and polyamine content in human adenocarcinomas of the stomach and large intestine]
Adenocarcinoma
[Therapy with inhibitors of polyamine biosynthesis in refractory prostatic carcinoma. An experimental and clinical study]
Adenoma
Assessment of ornithine decarboxylase activity in rectal mucosa as a marker for colorectal adenomas and carcinomas.
Adenoma
Association between the ornithine decarboxylase G316A polymorphism and breast cancer survival.
Adenoma
Beta-adrenergic responsiveness and cardiac autonomic receptors after implantation of the MtTW15 pituitary adenoma in the rat.
Adenoma
Clinical relevance of proliferation biomarkers and p53 expression in rectal mucosa and sporadic colonic adenomas: a prospective study.
Adenoma
Colon ornithine decarboxylase activity following standard endoscopy preparation regimens.
Adenoma
Colonic polyamine content and ornithine decarboxylase activity as markers for adenomas.
Adenoma
Colorectal ornithine decarboxylase activity in human mucosa and tumors: elevation of enzymatic activity in distal mucosa.
Adenoma
Correlation between bromodeoxyuridine labelling and ornithine decarboxylase levels in normal rectal mucosa of patients with colorectal adenoma.
Adenoma
Development of difluoromethylornithine as a chemoprevention agent for the management of colon cancer.
Adenoma
Efficacy and safety of eflornithine (CPP-1X)/sulindac combination therapy versus each as monotherapy in patients with familial adenomatous polyposis (FAP): design and rationale of a randomized, double-blind, Phase III trial.
Adenoma
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line.
Adenoma
Increased mucosal ornithine decarboxylase activity in large bowel with multiple tumors, adenocarcinoma, and adenoma.
Adenoma
L-arginine reduces cell proliferation and ornithine decarboxylase activity in patients with colorectal adenoma and adenocarcinoma.
Adenoma
Levels of colorectal ornithine decarboxylase activity in patients with colon cancer, a family history of nonpolyposis hereditary colorectal cancer, and adenomas.
Adenoma
Methylation status of CpG islands in the promoter region of genes differentially expressed in colonic mucosa from adenoma patients and controls in response to altered vegetable intake.
Adenoma
Novel Methods of Risk Stratifying Patients for Metachronous, Pre-Malignant Colorectal Polyps: A Systematic Review.
Adenoma
Novel patterns of gene expression in pituitary adenomas identified by complementary deoxyribonucleic acid microarrays and quantitative reverse transcription-polymerase chain reaction.
Adenoma
Ornithine decarboxylase G316A genotype is prognostic for colorectal adenoma recurrence and predicts efficacy of aspirin chemoprevention.
Adenoma
Ornithine decarboxylase levels in the rectal mucosa of patients with colonic neoplasia.
Adenoma
Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention.
Adenoma
Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention.
Adenoma
Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.
Adenoma
Rectal mucosal ornithine decarboxylase activity is not a useful marker of risk for colorectal neoplasia.
Adenoma
Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.
Adenoma
Variants downstream of the ornithine decarboxylase gene influence risk of colorectal adenoma and aspirin chemoprevention.
Adenoma
[A study of ornithine decarboxylase activity in tumor tissue and rectal mucosa in patients with colorectal cancer or adenoma]
Adenoma
[The ornithine decarboxylase activity of the gastric remnant mucosa: the effect of the duodenal juice with bile on the gastric mucosa]
Adenomatous Polyposis Coli
APC-dependent regulation of ornithine decarboxylase in human colon tumor cells.
Adenomatous Polyposis Coli
Biochemical markers in colorectal cancer: diagnostic and therapeutic implications.
Adenomatous Polyposis Coli
Efficacy and safety of eflornithine (CPP-1X)/sulindac combination therapy versus each as monotherapy in patients with familial adenomatous polyposis (FAP): design and rationale of a randomized, double-blind, Phase III trial.
Adenomatous Polyposis Coli
Ornithine decarboxylase and polyamines in familial adenomatous polyposis.
Adenomatous Polyposis Coli
Ornithine decarboxylase as a marker for premalignancy in the stomach.
Adenomatous Polyposis Coli
Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis.
Adenomatous Polyposis Coli
Rectal mucosal ornithine decarboxylase activity in familial adenomatous polyposis after ileorectal anastomosis.
Adenomatous Polyps
A randomized, placebo-controlled trial of low-dose alpha-difluoromethylornithine in individuals at risk for colorectal cancer.
Adenomatous Polyps
Colonic polyamine content and ornithine decarboxylase activity as markers for adenomas.
Adenomatous Polyps
Differential activation of ornithine decarboxylase and tyrosine kinase in the rectal mucosa of patients with hyperplastic and adenomatous polyps.
Adenomatous Polyps
Failure of rectal ornithine decarboxylase to identify adenomatous polyp status.
Adenomatous Polyps
Ornithine decarboxylase and glutamate decarboxylase 65 as prognostic markers of gallbladder malignancy: a clinicopathological study in benign and malignant lesions of the gallbladder.
Adenomatous Polyps
Supplemental calcium suppresses colonic mucosal ornithine decarboxylase activity in elderly patients with adenomatous polyps.
Adenomatous Polyps
The effect of high doses of folic acid on the overexpression of ornithine decarboxylase and S-adenosylmethionine content in human colon adenomatous polyps.
Albuminuria
Acute glomerular upregulation of ornithine decarboxylase is not essential for mesangial cell proliferation and matrix expansion in anti-Thy-1-nephritis.
Alkalosis
Effect of variations in blood hydrogen ion concentration on pulmonary gas exchange of artificially ventilated dogs.
Alopecia
Association of a polymorphism in the ornithine decarboxylase gene with male androgenetic alopecia.
Alopecia
Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis.
Alopecia
Modulation of murine hair follicle function by alterations in ornithine decarboxylase activity.
Alopecia
Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease.
Alopecia
[Studies on enzyme activities in the hair root in male pattern baldness: glycolytic enzyme, acid hydrolase, transglutaminase and ornithine decarboxylase activities of plucked hair roots]
Alzheimer Disease
Altered subcellular localization of ornithine decarboxylase in Alzheimer's disease brain.
Alzheimer Disease
Brain Neurons Express Ornithine Decarboxylase-Activating Antizyme Inhibitor 2 with Accumulation in Alzheimer's Disease.
Alzheimer Disease
Ornithine decarboxylase in human brain: influence of aging, regional distribution, and Alzheimer's disease.
Alzheimer Disease
Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity.
Amebiasis
Characterization of the Entamoeba histolytica Ornithine Decarboxylase-Like Enzyme.
Amyotrophic Lateral Sclerosis
Regional and temporal alterations of ODC/polyamine system during ALS-like neurodegenerative motor syndrome in G93A transgenic mice.
Anaplasia
Ornithine decarboxylase activity, prolactin blood levels, and estradiol and progesterone receptors in human breast cancer.
Androgen-Insensitivity Syndrome
Steroid regulation of kidney histidine decarboxylase and ornithine decarboxylase levels in mouse kidney: effects of the mutation testicular feminization, Tfm.
Anemia
Safety and Efficacy of Laparoscopic Oophorocystectomy for Ovarian Dermoid Cyst Associated With Autoimmune Hemolytic Anemia.
Anemia, Hemolytic
Remarkable activation of polyamine biosynthesis in hematopoiesis and hyperplasia of spleen in mice with hemolytic anemia caused by infection with Plasmodium berghei.
Anemia, Hemolytic, Autoimmune
Safety and Efficacy of Laparoscopic Oophorocystectomy for Ovarian Dermoid Cyst Associated With Autoimmune Hemolytic Anemia.
Anemia, Hypochromic
Inhibition of ornithine decarboxylase activity by phaseolotoxin: implications for symptom production in halo blight of French bean.
Anemia, Hypoplastic, Congenital
Elevation of pyrimidine enzyme activities in the RBC of patients with congenital hypoplastic anaemia and their parents.
Aortic Coarctation
Multiple polyamine regulatory pathways control compensatory cardiovascular hypertrophy in coarctation hypertension.
Arthritis
?-Difluoromethylornithine suppresses inflammatory arthritis by impairing myeloid-derived suppressor cells.
Arthritis
Diurnal rhythms in ornithine decarboxylase activity and norepinephrine and acetylcholine synthesis in submaxillary lymph nodes and spleen of young and aged rats during Freund's adjuvant-induced arthritis.
Arthritis
Effects of lentivirus-mediated ornithine decarboxylase gene on the proliferation and apoptosis of fibroblast-like synoviocytes in rats with arthritis.
Arthritis
Hyperprolactinaemia in hypophysectomized or intact male rats and the development of adjuvant arthritis.
Arthritis
Methylacetylenic putrescine (MAP), an inhibitor of polyamine biosynthesis, prevents the development of collagen-induced arthritis.
Arthritis, Experimental
[The study on the relationship between the tumor-like proliferation of synoviocytes and the expression of C-myc and ODC genes in adjuvant arthritis rats.]
Arthritis, Rheumatoid
Effects of lentivirus-mediated ornithine decarboxylase gene on the proliferation and apoptosis of fibroblast-like synoviocytes in rats with arthritis.
Astrocytoma
Calcium and microtubule dependence for increased ornithine decarboxylase activity stimulated by beta-adrenergic agonists, dibutyryl cyclic AMP, or serum in a rat astrocytoma cell line.
Astrocytoma
Degree of enhancement of polyamine biosynthetic decarboxylase activities in human tumors: a useful new index of degree of malignancy.
Astrocytoma
Degrees of malignancy in human primary central nervous system tumors: ornithine decarboxylase levels as better indicators than adenosylmethionine decarboxylase levels.
Astrocytoma
Phase II trial of recombinant interferon-alpha-2a and eflornithine in patients with recurrent glioma.
Ataxia Telangiectasia
An apparent correlation between the inhibition of induced ornithine decarboxylase activity by gamma radiation and the capacity for DNA repair synthesis in normal and ataxia telangiectasia human fibroblasts: no correlation with cell survival.
Ataxia Telangiectasia
Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes.
Atherosclerosis
Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury.
Atherosclerosis
ODC (Ornithine Decarboxylase)-Dependent Putrescine Synthesis Maintains MerTK (MER Tyrosine-Protein Kinase) Expression to Drive Resolution.
Avitaminosis
Hepatic or pulmonary ornithine decarboxylase and vitamin A status in Wistar rat, enzyme kinetics--influence of chloroform.
Avitaminosis
Ornithine decarboxylase basal activity in liver, oesophagus and lung of vitamin A deficient rats, and the effect of retinoic acid.
Avitaminosis
Role of pyridoxal phosphate in mammalian polyamine biosynthesis. Lack of requirement for mammalian S-adenosylmethionine decarboxylase activity.
Bacterial Infections
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Bacterial Infections
Rainbow trout (Oncorhynchus mykiss) urea cycle and polyamine synthesis gene families show dynamic expression responses to inflammation.
Barrett Esophagus
Increase in ornithine decarboxylase activity associated with development of dysplasia in Barrett's esophagus.
Barrett Esophagus
Ornithine decarboxylase activity in Barrett's esophagus: a potential marker for dysplasia.
Barrett Esophagus
Ornithine decarboxylase and polyamine levels in columnar upper gastrointestinal mucosae in patients with Barrett's esophagus.
Barrett Esophagus
Upregulation of ornithine decarboxylase mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma.
Blast Crisis
[Certain biochemical features of leukocytes in blast crisis of chronic myelogenous leukemia]
Blindness
Optic Disc Coloboma in children - prevalence, clinical characteristics and associated morbidity.
Bone Resorption
Alpha-difluoromethylornithine inhibits bone resorption in vitro without decreasing beta-glucuronidase release.
Bowen's Disease
Immunohistochemical localization of ornithine decarboxylase in skin tumors.
Brain Diseases
Brain Neurons Express Ornithine Decarboxylase-Activating Antizyme Inhibitor 2 with Accumulation in Alzheimer's Disease.
Brain Diseases
The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems.
Brain Edema
Ornithine decarboxylase activity and edema formation in cerebral ischemia of conscious gerbils.
Brain Edema
Ornithine decarboxylase activity and immunohistochemical location in postischemic brain.
Brain Edema
Osteoplastic decompressive craniotomy-an alternative to decompressive craniectomy.
Brain Infarction
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Brain Injuries
Effect of difluoromethylornithine treatment on regional ornithine decarboxylase activity and edema formation after experimental brain injury.
Brain Injuries
Induction of brain ornithine decarboxylase after systemic or intrastriatal administration of kainic acid.
Brain Injuries
Overexpression of spermidine/spermine N-acetyltransferase in transgenic mice protects the animals from kainate-induced toxicity.
Brain Injuries
Regional activity of ornithine decarboxylase and edema formation after traumatic brain injury.
Brain Injuries, Traumatic
Activation of ornithine decarboxylase and accumulation of putrescine after traumatic brain injury.
Brain Injuries, Traumatic
Increased ornithine decarboxylase activity and protein level in the cortex following traumatic brain injury in rats.
Brain Injuries, Traumatic
Regional activity of ornithine decarboxylase and edema formation after traumatic brain injury.
Brain Injuries, Traumatic
Simultaneous assay of ornithine decarboxylase and polyamines after central nervous system injury in gerbil and rat.
Brain Ischemia
Activity of ornithine decarboxylase and S-adenosylmethionine decarboxylase in transient cerebral ischemia: relationship to the duration of vascular occlusion.
Brain Ischemia
Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage.
Brain Ischemia
Induction of ornithine decarboxylase mRNA in transient focal cerebral ischemia in the rat.
Brain Ischemia
Modulation of ischemic signal by antagonists of N-methyl-D-aspartate, nitric oxide synthase, and platelet-activating factor in gerbil hippocampus.
Brain Ischemia
Ornithine decarboxylase activity and edema formation in cerebral ischemia of conscious gerbils.
Brain Ischemia
Ornithine decarboxylase activity and immunohistochemical location in postischemic brain.
Brain Ischemia
Ornithine decarboxylase activity and putrescine levels in reversible cerebral ischemia of Mongolian gerbils: effect of barbiturate.
Brain Ischemia
Ornithine decarboxylase activity in in vivo and in vitro models of cerebral ischemia.
Brain Ischemia
Ornithine decarboxylase in reversible cerebral ischemia: an immunohistochemical study.
Brain Ischemia
Ornithine decarboxylase knockdown exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain.
Brain Ischemia
Polyamines induce blood-brain barrier disruption and edema formation in the rat.
Brain Ischemia
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Brain Ischemia
[Effect of alpha-difluoromethylornithine on the expression of ODC mRNA in the cortex and hippocampus in rats after cerebral ischemia reperfusion]
Brain Neoplasms
Activity of ornithine decarboxylase (ODC) and polyamine levels as biochemical markers of malignancy in human brain tumors.
Brain Neoplasms
alpha-Difluoromethylornithine alters calcium signaling in platelet-derived growth factor-stimulated A172 brain tumor cells in culture.
Brain Neoplasms
Cell proliferation and polyamine metabolism in 9L cells treated with (2R,5R)-6-heptyne-2,5-diamine or alpha-difluoromethylornithine.
Brain Neoplasms
Decreased cytotoxicity of 1-beta-D-arabinofuranosylcytosine in 9L rat brain tumor cells pretreated with alpha-difluoromethylornithine in vitro.
Brain Neoplasms
Degree of enhancement of polyamine biosynthetic decarboxylase activities in human tumors: a useful new index of degree of malignancy.
Brain Neoplasms
Differential potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine in chloroethylnitrosourea-sensitive and -resistant 9L rat brain tumor cells in vitro.
Brain Neoplasms
Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro.
Brain Neoplasms
Phase I-II study of eflornithine and mitoguazone combined in the treatment of recurrent primary brain tumors.
Brain Neoplasms
Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry.
Brain Neoplasms
Possible factors in the potentiation of 1-(2-chloroethyl)-3-trans-4-methylcyclohexyl-1-nitrosourea cytotoxicity by alpha-difluoromethylornithine in 9L rat brain tumor cells.
Brain Neoplasms
Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L rat brain tumor cells by methylglyoxal-bis(guanylhydrazone), an inhibitor of S-adenosyl-L-methionine decarboxylase.
Brain Neoplasms
Reduction in cis-diamminedichloroplatinum(II)-induced cytotoxicity, sister chromatid exchange, and DNA interstrand cross-links in 9L cells treated with the polyamine biosynthesis inhibitor (2R,5R)-6-heptyne-2,5-diamine.
Brain Neoplasms
Regional distribution of ornithine decarboxylase activity and polyamine levels in experimental cat brain tumors.
Branchio-Oto-Renal Syndrome
Multimodal Imaging of Large Optic Disc Coloboma: A Report of Three Cases.
Breast Diseases
Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters.
Breast Neoplasms
A phase II breast cancer chemoprevention trial of oral alpha-difluoromethylornithine: breast tissue, imaging, and serum and urine biomarkers.
Breast Neoplasms
A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer.
Breast Neoplasms
Activation of protein kinase A (PKA) signaling mitigates the antiproliferative and antiinvasive effects of alpha-difluoromethylornithine in breast cancer cells.
Breast Neoplasms
Aminoglutethimide, a steroidogenesis inhibitor, abolishes hormonal induction of ornithine decarboxylase in steroidogenic tissues: evidence for its role as cAMP-dependent protein kinase inhibitor.
Breast Neoplasms
Anticancer action of cubé insecticide: correlation for rotenoid constituents between inhibition of NADH:ubiquinone oxidoreductase and induced ornithine decarboxylase activities.
Breast Neoplasms
Association between the ornithine decarboxylase G316A polymorphism and breast cancer survival.
Breast Neoplasms
Biochemical and growth-modulatory effects of the new S-adenosylmethionine decarboxylase inhibitor CGP 48664 in malignant and immortalized normal human breast epithelial cells in culture.
Breast Neoplasms
Cellular mechanisms mediating the anti-invasive properties of the ornithine decarboxylase inhibitor alpha-difluoromethylornithine (DFMO) in human breast cancer cells.
Breast Neoplasms
Chemoprevention and chemotherapy by inhibition of ornithine decarboxylase activity and polyamine synthesis: colonic, pancreatic, mammary, and renal carcinomas.
Breast Neoplasms
Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and the proliferation of human breast cancer cell lines.
Breast Neoplasms
Comparative studies on the polyamine metabolism and DFMO treatment of MCF-7 and MDA-MB-231 breast cancer cell lines and xenografts.
Breast Neoplasms
Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies.
Breast Neoplasms
Detection of ornithine decarboxylase mRNA in human breast cancer MCF-7 cells by in situ RT-PCR.
Breast Neoplasms
Dual Inhibition of Ornithine Decarboxylase and A1 Adenosine Receptor Efficiently Suppresses Breast Tumor Cells.
Breast Neoplasms
Effect of D,L-2-difluoromethylornithine and endocrine manipulation on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
Breast Neoplasms
Effective chemopreventive activity of genistein against human breast cancer cells.
Breast Neoplasms
Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice.
Breast Neoplasms
Effects of methylacetylenic putrescine, an ornithine decarboxylase inhibitor and potential novel anticancer agent, on human and mouse cancer cell lines.
Breast Neoplasms
Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications.
Breast Neoplasms
Estrogen-dependent regulation of ornithine decarboxylase in breast cancer cells through activation of nongenomic cAMP-dependent pathways.
Breast Neoplasms
Expression of ornithine decarboxylase mRNA and c-myc mRNA in breast tumours.
Breast Neoplasms
Genetic polymorphism in ornithine decarboxylase and risk of breast cancer.
Breast Neoplasms
Histone H1 inhibits the proliferation of MCF 7 and MDA MB 231 human breast cancer cells.
Breast Neoplasms
Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase.
Breast Neoplasms
Immunohistochemical detection of ornithine-decarboxylase in primary and metastatic human breast cancer specimens.
Breast Neoplasms
Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells.
Breast Neoplasms
Inhibition of ornithine decarboxylase alters the roscovitine-induced mitochondrial-mediated apoptosis in MCF-7 breast cancer cells.
Breast Neoplasms
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
Breast Neoplasms
Inhibitors of polyamine biosynthesis decrease the expression of the metalloproteases meprin alpha and MMP-7 in hormone-independent human breast cancer cells.
Breast Neoplasms
Intrinsic and extrinsic factors in estrogen action in human breast cancer: role of polyamines and pituitary factors.
Breast Neoplasms
Involvement of the polyamine pathway in antiestrogen-induced growth inhibition of human breast cancer.
Breast Neoplasms
Isolation and characterization of human breast cancer cells overexpressing S-adenosylmethionine decarboxylase.
Breast Neoplasms
Measurement of mRNA levels in tumor xenografts with quantitative autoradiography and in situ hybridization.
Breast Neoplasms
Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment.
Breast Neoplasms
NADH: ubiquinone oxidoreductase inhibitors block induction of ornithine decarboxylase activity in MCF-7 human breast cancer cells.
Breast Neoplasms
Ornithine decarboxylase (ODC) as a prognostic factor in operable breast cancer.
Breast Neoplasms
Ornithine decarboxylase activity, prolactin blood levels, and estradiol and progesterone receptors in human breast cancer.
Breast Neoplasms
Ornithine decarboxylase and phosphatase activity can be stimulated by low concentrations of interferon in human breast cancer cell lines.
Breast Neoplasms
Phenotypic features of breast cancer cells overexpressing ornithine-decarboxylase.
Breast Neoplasms
Polyamine involvement in the growth of hormone-responsive and -resistant human breast cancer cells in culture.
Breast Neoplasms
Polyamine profiles and growth properties of ornithine decarboxylase overexpressing MCF-7 breast cancer cells in culture.
Breast Neoplasms
Polyamines and growth regulation of cultured human breast cancer cells by 17 beta-oestradiol.
Breast Neoplasms
Post-translational cooperativity of ornithine decarboxylase induction by estrogens and peptide growth factors in human breast cancer cells.
Breast Neoplasms
Prognostic influence on survival of increased ornithine decarboxylase activity in human breast cancer.
Breast Neoplasms
Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters.
Breast Neoplasms
Regulation of ornithine decarboxylase gene expression in MCF-7 breast cancer cells by antiestrogens.
Breast Neoplasms
Regulation of ornithine decarboxylase mRNA levels in human breast cancer cells: pattern of expression and involvement of core enhancer promoter element.
Breast Neoplasms
Role of non-receptor and receptor tyrosine kinases (TKs) in the antitumor action of alpha-difluoromethylornithine (DFMO) in breast cancer cells.
Breast Neoplasms
Role of ornithine decarboxylase in regulation of estrogen receptor alpha expression and growth in human breast cancer cells.
Breast Neoplasms
Selectivity of polyamine involvement in hormone action on normal and neoplastic target tissues of the rat.
Breast Neoplasms
Serum polyamines in pre- and post-operative patients with breast cancer corrected by menopausal status.
Breast Neoplasms
Targeting polyamine biosynthetic pathway through RNAi causes the abrogation of MCF 7 breast cancer cell line.
Breast Neoplasms
Urtica dioica inhibits cell growth and induces apoptosis by targeting Ornithine decarboxylase and Adenosine deaminase as key regulatory enzymes in adenosine and polyamines homeostasis in human breast cancer cell lines.
Breast Neoplasms
Variations in amplification and expression of the ornithine decarboxylase gene in human breast cancer cells.
Breast Neoplasms
Visualization and characterization of cancer stem-like cells in cervical cancer.
Burkitt Lymphoma
Anti-IgM-induced growth inhibition and apoptosis are independent of ornithine decarboxylase in Ramos cells.
Burkitt Lymphoma
Effect of alpha-difluoromethylornithine alone and in combination with doxorubicin hydrochloride, cis-diamminedichloroplatinum (II), and vinblastine sulfate on the growth of P3J cells in vitro.
Carcinogenesis
1,4-phenylenebis(methylene)selenocyanate exerts exceptional chemopreventive activity in rat tongue carcinogenesis.
Carcinogenesis
A comparative evaluation of the anticancer properties of European and American elderberry fruits.
Carcinogenesis
A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients.
Carcinogenesis
A novel geranylated derivative, ethyl 3-(4'-geranyloxy-3'-methoxyphenyl)-2-propenoate, synthesized from ferulic acid suppresses carcinogenesis and inducible nitric oxide synthase in rat tongue.
Carcinogenesis
A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development.
Carcinogenesis
All-trans beta-carotene enhances mitogenic responses and ornithine decarboxylase activity of BALB/c 3T3 fibroblast cells induced by tumor promoter and fetal bovine serum but suppresses mutagen-dependent umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002).
Carcinogenesis
alpha-Difluoromethylornithine inhibits cell growth stimulated by a tumor-promoting rat urinary fraction.
Carcinogenesis
Alpha-difluoromethylornithine inhibits N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in zinc-deficient rats: effects on esophageal cell proliferation and apoptosis.
Carcinogenesis
alpha-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin.
Carcinogenesis
Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis.
Carcinogenesis
APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse.
Carcinogenesis
Apoptosis induction by the natural product cancer chemopreventive agent deguelin is mediated through the inhibition of mitochondrial bioenergetics.
Carcinogenesis
Apoptosis inhibition and ornithine decarboxylase superinduction as early epigenetic events in morphological transformation of Syrian hamster embryo cells exposed to 2-methoxyacetaldehyde, a metabolite of 2-methoxyethanol.
Carcinogenesis
Arsenite, but not cadmium, induces ornithine decarboxylase and heme oxygenase activity in rat liver: relevance to arsenic carcinogenesis.
Carcinogenesis
Attenuating effect of ornithine decarboxylase inhibitor (1,3-diaminopropane) on bombesin enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.
Carcinogenesis
Attenuation by d-limonene of sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Carcinogenesis
Attenuation of vasoactive intestinal peptide enhancement of colon carcinogenesis by ornithine decarboxylase inhibitor.
Carcinogenesis
Bifidobacterium longum, a lactic acid-producing intestinal bacterium inhibits colon cancer and modulates the intermediate biomarkers of colon carcinogenesis.
Carcinogenesis
Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation.
Carcinogenesis
Cancer therapy and prevention by green tea: role of ornithine decarboxylase.
Carcinogenesis
Cell kinetic analysis of the mucosal epithelium and assay of ornithine decarboxylase activity during the process of 1-hydroxyanthraquinone-induced large bowel carcinogenesis in rats.
Carcinogenesis
Characterization and immunolocalization of mutated ornithine decarboxylase antizyme from Angiostrongylus cantonensis.
Carcinogenesis
Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells.
Carcinogenesis
Chemoprevention by naturally occurring and synthetic agents in oral, liver, and large bowel carcinogenesis.
Carcinogenesis
Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal antiinflammatory drug with D,L-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet.
Carcinogenesis
Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis.
Carcinogenesis
Chemoprevention of human actinic keratoses by topical 2-(difluoromethyl)-dl-ornithine.
Carcinogenesis
Chemoprevention of oral carcinogenesis by DL-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor: dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats.
Carcinogenesis
Chemopreventive effect of bovine lactoferrin on 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male F344 rats.
Carcinogenesis
Chemopreventive effects of alpha-santalol on skin tumor development in CD-1 and SENCAR mice.
Carcinogenesis
Chemopreventive Potential of Wild Lowbush Blueberry Fruits in Multiple Stages of Carcinogenesis
Carcinogenesis
Chronic stress decreases ornithine decarboxylase expression and protects against 1,2-dimethylhydrazine-induced colon carcinogenesis.
Carcinogenesis
Comparison of ultraviolet light-induced skin carcinogenesis and ornithine decarboxylase activity in sencar and hairless SKH-1 mice fed a constant level of dietary lipid varying in corn and coconut oil.
Carcinogenesis
Complex interactions at a GC-rich domain regulate cell type-dependent activity of the ornithine decarboxylase promoter.
Carcinogenesis
Core promoter involvement in the induction of rat ornithine decarboxylase by phorbol esters.
Carcinogenesis
Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients.
Carcinogenesis
Detection of ornithine decarboxylase messenger RNA in human hepatocellular carcinoma by in situ hybridization.
Carcinogenesis
Development of difluoromethylornithine as a chemoprevention agent for the management of colon cancer.
Carcinogenesis
Dietary protein enhanced mammary ornithine decarboxylase activity and tumorigenesis in rats.
Carcinogenesis
Difluoromethylornithine chemoprevention of epidermal carcinogenesis in K14-HPV16 transgenic mice.
Carcinogenesis
Dimethylarsinic acid treatment alters six different rat biochemical parameters: relevance to arsenic carcinogenesis.
Carcinogenesis
Dissimilar activation patterns of the carcinogen dimethylhydrazine (DMH) on intracellular polyamine metabolism in various organs.
Carcinogenesis
Effect of 1,8-dihydroxy-9-anthrone (anthralin) on rat hepatic ornithine decarboxylase activity in vivo.
Carcinogenesis
Effect of Aegle marmelos on DEN initiated and 2-AAF promoted hepatocarcinogenesis: a chemopreventive study.
Carcinogenesis
Effect of beta-carotene supplementation on the activity of ornithine decarboxylase (ODC) in stomach mucosa of patients with chronic atrophic gastritis.
Carcinogenesis
Effect of chemopreventive agents on intermediate biomarkers during different stages of azoxymethane-induced colon carcinogenesis.
Carcinogenesis
Effect of chemopreventive agents on posttranslational plasmamembrane association of ras-p21 during chemoprevention of azoxymethane-induced colon carcinogenesis.
Carcinogenesis
Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models.
Carcinogenesis
Effect of different levels of calorie restriction on azoxymethane-induced colon carcinogenesis in male F344 rats.
Carcinogenesis
Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats.
Carcinogenesis
Effect of ornithine decarboxylase inhibitor on tetragastrin treatment of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Carcinogenesis
Effect of prolonged beta-carotene or DL-alpha-tocopheryl acetate supplementation on ornithine decarboxylase activity in human atrophic stomach mucosa.
Carcinogenesis
Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target.
Carcinogenesis
Effect of the chemopreventive agents piroxicam and D,L-alpha-difluoromethylornithine on intermediate biomarkers of colon carcinogenesis.
Carcinogenesis
Effective suppression of azoxymethane-induced aberrant crypt foci formation in mice with citrus peel flavonoids.
Carcinogenesis
Effects of alpha-difluoromethylornithine on initiation and promotion of urinary bladder carcinogenesis in a heterotopically transplanted rat urinary bladder.
Carcinogenesis
Effects of butylated hydroxytoluene upon PUVA-tumorigenesis and induction of ornithine decarboxylase activity in the mouse.
Carcinogenesis
Effects of C-Phycocyanin on the representative genes of tumor development in mouse skin exposed to 12-O-tetradecanoyl-phorbol-13-acetate.
Carcinogenesis
Effects of chronically elevated growth hormone levels on polyamine metabolism in elderly transgenic mice.
Carcinogenesis
Effects of combined treatments with selenium, glutathione, and vitamin E on glutathione peroxidase activity, ornithine decarboxylase induction, and complete and multistage carcinogenesis in mouse skin.
Carcinogenesis
Effects of D,L-2-difluoromethylornithine and indomethacin on mammary tumor promotion in rats fed high n-3 and/or n-6 fat diets.
Carcinogenesis
Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.
Carcinogenesis
Effects of psoralen from Psoralea corylifolia on quinone reductase, ornithine decarboxylase, and JB6 cells transformation promotion.
Carcinogenesis
Effects of timing of administration and dose of difluoromethylornithine on rat colonic carcinogenesis.
Carcinogenesis
eIF4E expression in tumors: its possible role in progression of malignancies.
Carcinogenesis
Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites.
Carcinogenesis
Enhancement by adriamycin of the effects of 12-O-tetradecanoylphorbol-13-acetate on mouse epidermal glutathione peroxidase activity, ornithine decarboxylase induction and skin tumor promotion.
Carcinogenesis
Enhancement by aminoguanidine of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Carcinogenesis
Epigenetic events during the process of cell transformation induced by carcinogens (review).
Carcinogenesis
Epithelial cell proliferation in the digestive tract induced by space restriction and water-immersion stress.
Carcinogenesis
Evaluation of possible mechanisms of protective role of Tamarix gallica against DEN initiated and 2-AAF promoted hepatocarcinogenesis in male Wistar rats.
Carcinogenesis
Events associated with mouse skin tumor promotion with respect to arachidonic acid metabolism: a comparison between SENCAR and NMRI mice.
Carcinogenesis
Experimental carcinogenesis in the rat intestine induced by two different carcinogens--evaluation of carcinogenic action and its effect on ornithine decarboxylase activity.
Carcinogenesis
Expression of epidermal growth factor receptor, polyamine levels, ornithine decarboxylase activity, micronuclei, and transglutaminase I in a 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model.
Carcinogenesis
Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress.
Carcinogenesis
Gene expression of ornithine decarboxylase, cyclooxygenase-2, and gastrin in atrophic gastric mucosa infected with Helicobacter pylori before and after eradication therapy.
Carcinogenesis
Genetic alterations of the ornithine decarboxylase gene in human colorectal cancers.
Carcinogenesis
Genetically determined differences in the response to carcinogens of aryl hydrocarbon hydroxylase and ornithine decarboxylase.
Carcinogenesis
Genistein as antioxidant and antibrowning agents in in vivo and in vitro: A review.
Carcinogenesis
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line.
Carcinogenesis
Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors.
Carcinogenesis
Heterogenicity of ornithine decarboxylase during mouse colon carcinogenesis and in human colon tumors.
Carcinogenesis
High levels of intracellular polyamines promote histone acetyltransferase activity resulting in chromatin hyperacetylation.
Carcinogenesis
Identification of an X-linked locus modifying mouse skin tumor susceptibility.
Carcinogenesis
In vitro induction of ornithine decarboxylase in urinary bladder carcinoma cells.
Carcinogenesis
Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase.
Carcinogenesis
Induction of hepatic ornithine decarboxylase by hypolipidemic drugs with hepatic peroxisome proliferative activity.
Carcinogenesis
Induction of mouse brain ornithine decarboxylase by 12-O-tetradecanoylphorbol-13-acetate is independent of TPA receptor concentration.
Carcinogenesis
Induction of mouse epidermal ornithine decarboxylase activity and skin tumors by 7,12-dimethylben.
Carcinogenesis
Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis.
Carcinogenesis
Induction of putative tumor-suppressing genes in Rat-1 fibroblasts by oncogenic Raf-1 as evidenced by robot-assisted complex hybridization.
Carcinogenesis
Influence of glutathione S-transferase pi and p53 expression on tumor frequency and spectrum in mice.
Carcinogenesis
Influence of K-ras activation on the survival responses of Caco-2 cells to the chemopreventive agents sulindac and difluoromethylornithine.
Carcinogenesis
Inhibition by calmodulin antagonist trifluoperazine of experimental carcinogenesis in rat colon induced by azoxymethane.
Carcinogenesis
Inhibition by the calmodulin antagonist trifluoperazine of experimental hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
Carcinogenesis
Inhibition of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin ornithine decarboxylase and protein kinase C by polyphenolics from grapes.
Carcinogenesis
Inhibition of expression of ornithine decarboxylase by c-myc antisense oligonucleotide at the promotion stage of lung tumorigenesis in mice.
Carcinogenesis
Inhibition of intestinal carcinogenesis in rats: effect of difluoromethylornithine with piroxicam or fish oil.
Carcinogenesis
Inhibition of methylnitrosourea-induced large bowel cancer development in rats by sarcophytol A, a product from a marine soft coral Sarcophyton glaucum.
Carcinogenesis
Inhibition of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis by alpha-difluoromethylornithine.
Carcinogenesis
Inhibition of ornithine decarboxylase activity by small doses of alpha-difluoromethylornithine.
Carcinogenesis
Inhibition of tumor promoter-induced ornithine decarboxylase activity by tannic acid and other polyphenols in mouse epidermis in vivo.
Carcinogenesis
Inhibition of tumor promotion by DL-alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase.
Carcinogenesis
Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid.
Carcinogenesis
Inhibition of ultraviolet-B epidermal ornithine decarboxylase induction and skin carcinogenesis in hairless mice by topical indomethacin and triamcinolone acetonide.
Carcinogenesis
Inhibition of ultraviolet-B skin carcinogenesis by all-trans-retinoic acid regimens that inhibit ornithine decarboxylase induction.
Carcinogenesis
Inhibitory action of alpha-difluoromethylornithine on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis.
Carcinogenesis
Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon.
Carcinogenesis
Inhibitory effects of 1,3-diaminopropane, an ornithine decarboxylase inhibitor, on rat two-stage urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Carcinogenesis
Inhibitory effects of glutathione level-raising agents and D-alpha-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Carcinogenesis
Inhibitory effects of soy isoflavones on rat prostate carcinogenesis induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Carcinogenesis
Intermediate biomarkers of colon cancer: modulation of expression of ras oncogene by chemopreventive agents during azoxymethane induced colon carcinogenesis.
Carcinogenesis
Investigating Ornithine Decarboxylase Posttranscriptional Regulation Via a Pulldown Assay Using Biotinylated Transcripts.
Carcinogenesis
Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-?/Smad signaling pathway.
Carcinogenesis
Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch.
Carcinogenesis
Kinetic changes in mucosal ornithine decarboxylase activity during azoxymethane-induced colonic carcinogenesis in the rat.
Carcinogenesis
Life-long over-expression of ornithine decarboxylase (ODC) gene in transgenic mice does not lead to generally enhanced tumorigenesis or neuronal degeneration.
Carcinogenesis
Liver ornithine decarboxylase during phenobarbital promotion of nitrosamine carcinogenesis.
Carcinogenesis
Magnetic field exposure increases cell proliferation but does not affect melatonin levels in the mammary gland of female Sprague Dawley rats.
Carcinogenesis
Modulating effect of amount and types of dietary fat on ornithine decarboxylase, tyrosine protein kinase and prostaglandins production during colon carcinogenesis in male F344 rats.
Carcinogenesis
Modulation of biologic endpoints by topical difluoromethylornithine (DFMO), in subjects at high-risk for nonmelanoma skin cancer.
Carcinogenesis
Modulatory effects of Pluchea lanceolata against chemically induced oxidative damage, hyperproliferation and two-stage renal carcinogenesis in Wistar rats.
Carcinogenesis
Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: key role of polyamines?
Carcinogenesis
ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.
Carcinogenesis
Ornithine Decarboxylase (ODC) Expression Pattern in Human Prostate Tissues and ODC Transgenic Mice.
Carcinogenesis
Ornithine decarboxylase activity in the mucosa of gastric remnant following gastric surgery.
Carcinogenesis
Ornithine decarboxylase activity in tumor and normal tissue of head and neck cancer patients.
Carcinogenesis
Ornithine decarboxylase and glutamate decarboxylase 65 as prognostic markers of gallbladder malignancy: a clinicopathological study in benign and malignant lesions of the gallbladder.
Carcinogenesis
Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
Carcinogenesis
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Carcinogenesis
Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer.
Carcinogenesis
Ornithine decarboxylase inhibitor attenuates bombesin enhancement of intestinal carcinogenesis and metastasis induced by azoxymethane.
Carcinogenesis
Ornithine decarboxylase inhibitor attenuates NaCl enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.
Carcinogenesis
Ornithine decarboxylase inhibitor lessens the rat gastric carcinogenesis enhancement caused by tyrosine methyl ester.
Carcinogenesis
Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.
Carcinogenesis
Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling.
Carcinogenesis
Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer.
Carcinogenesis
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
Carcinogenesis
Ornithine decarboxylase overexpression leads to increased epithelial tumor invasiveness.
Carcinogenesis
Ornithine decarboxylase: a promising and exploratory candidate target for natural products in cancer chemoprevention.
Carcinogenesis
Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice.
Carcinogenesis
Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention.
Carcinogenesis
Possible mechanisms by which pro- and prebiotics influence colon carcinogenesis and tumor growth.
Carcinogenesis
Potent suppressive activity of nonpolyphenolic fraction of green tea (Camellia sinensis) against genotoxin-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002), tumor promotor-dependent ornithine decarboxylase induction of BALB/c 3T3 fibroblast cells, and chemically induced mouse skin tumorigenesis.
Carcinogenesis
Prevention of colon cancer by pre- and probiotics: evidence from laboratory studies.
Carcinogenesis
Prevention of inhibitory effects of alpha-difluoromethylornithine on rat urinary bladder carcinogenesis by exogenous putrescine.
Carcinogenesis
Promotion of skin carcinogenesis by dimethylarsinic acid in keratin (K6)/ODC transgenic mice.
Carcinogenesis
Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.
Carcinogenesis
Protective effect of the isoflavonoid equol against hairless mouse skin carcinogenesis induced by UV radiation alone or with a chemical cocarcinogen.
Carcinogenesis
Radiosynthesis and evaluation of N5-(2-18F-fluoropropanyl) ornithine as a potential agent for tumor PET imaging.
Carcinogenesis
Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention.
Carcinogenesis
Reduction of ornithine decarboxylase antizyme (ODC-Az) level in the 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model.
Carcinogenesis
Regulation of ornithine decarboxylase during oncogenic transformation: mechanisms and therapeutic potential.
Carcinogenesis
Regulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1.
Carcinogenesis
Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis.
Carcinogenesis
Relationship of ornithine decarboxylase activity and human colon tumorigenesis.
Carcinogenesis
Risk analysis of carcinogenesis in the remnant stomach with measurement of ornithine decarboxylase activity.
Carcinogenesis
Role of activation of ornithine decarboxylase and DNA synthesis on ethynylestradiol-induced hepatocarcinogenesis.
Carcinogenesis
Salix caprea inhibits skin carcinogenesis in murine skin: inhibition of oxidative stress, ornithine decarboxylase activity and DNA synthesis.
Carcinogenesis
Significance of arginase and ornithine in malignant tumors of the human skin.
Carcinogenesis
Sources of variability in estimating ornithine decarboxylase activity and polyamine contents in human colorectal mucosa.
Carcinogenesis
Specific binding, stimulation of rodent urinary bladder epithelial ornithine decarboxylase, and induction of transitional cell hyperplasia by the skin tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Carcinogenesis
Stable siRNA-mediated silencing of antizyme inhibitor: regulation of ornithine decarboxylase activity.
Carcinogenesis
Stimulating effect of excess iron feeding on spontaneous lung tumor promotion in mice.
Carcinogenesis
Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention.
Carcinogenesis
Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion.
Carcinogenesis
Suppression of chemical carcinogenesis by water-soluble organosulfur compounds.
Carcinogenesis
Systemic inhibition of tumor promoter-induced ornithine decarboxylase in 1 alpha-hydroxyvitamin D3-treated animals.
Carcinogenesis
Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis.
Carcinogenesis
Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression.
Carcinogenesis
Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma.
Carcinogenesis
Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.
Carcinogenesis
Terminalia Chebula Attenuates DMBA/Croton Oil-Induced Oxidative Stress and Inflammation in Swiss albino Mouse Skin.
Carcinogenesis
The chemopreventive agent alpha-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells.
Carcinogenesis
The differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the initiation-promotion protocol and by the complete carcinogenesis process.
Carcinogenesis
The effect of 6-methylthiohexyl isothiocyanate isolated from Wasabia japonica (wasabi) on 4-(methylnitrosamino)-1-(3-pyridyl)-1-buatnone-induced lung tumorigenesis in mice.
Carcinogenesis
The effects of dietary fiber from Lagenaria scineraria (yugao-melon) on colonic carcinogenesis in mice.
Carcinogenesis
The heterotopically transplanted rat urinary bladder as a model for detection of tumor-promoting urinary growth factor(s).
Carcinogenesis
The induction of ornithine decarboxylase as an early, possibly obligatory, event in mouse skin carcinogenesis.
Carcinogenesis
The inhibition of DMBA-induced carcinogenesis by neoxanthin in hamster buccal pouch.
Carcinogenesis
The inhibitory effect of vitamin E on arachidonic acid metabolism during the process of urethane-induced lung tumorigenesis in mice.
Carcinogenesis
The inhibitory effect of vitamin E on pulmonary polyamine biosynthesis, cell proliferation and carcinogenesis in mice.
Carcinogenesis
The modulation effect of vitamin E on prostaglandin E2 level and ornithine decarboxylase activity at the promotion phase of lung tumorigenesis in mice.
Carcinogenesis
The ODC 3'-Untranslated Region and 5'-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis.
Carcinogenesis
The relevance of piroxicam for the prevention and treatment of nonmelanoma skin cancer and its precursors.
Carcinogenesis
The suppression of ornithine decarboxylase expression and cell proliferation at the promotion stage of lung tumorigenesis in mice by alpha-tocopheryloxybutyric acid.
Carcinogenesis
Tip60 Protein Isoforms and Altered Function in Skin and Tumors that Overexpress Ornithine Decarboxylase.
Carcinogenesis
Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth.
Carcinogenesis
Two-stage exposure of Syrian-hamster-embryo cells to environmental carcinogens: superinduction of ornithine decarboxylase correlates with increase of morphological-transformation frequency.
Carcinogenesis
Ultraviolet radiation induction of ornithine decarboxylase in rat keratinocytes.
Carcinogenesis
Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B.
Carcinogenesis
[A study of ornithine decarboxylase activity in tumor tissue and rectal mucosa in patients with colorectal cancer or adenoma]
Carcinogenesis
[Ornithine decarboxylase (ODC) activity in the mucosa of human remnant stomach, and the clinical significance on tumor promotion]
Carcinogenesis
[Ornithine decarboxylase activity and polyamine contents in 1,2-dimethylhydrazine-induced carcinogenesis of the intestines in rats]
Carcinogenesis
[Potential cancer-protective effect of beta-carotene in experimental stomach carcinogenesis]
Carcinogenesis
[Regulation of tumor promotion by 1 alpha, 25-dihydroxyvitamin D3, an active form of vitamin D3]
Carcinogenesis
[Role in mucosal ornithine decarboxylase activity during dimethylhydrazine-induced colonic carcinogenesis in the rat]
Carcinogenesis
[The actions of TPA-type as well as non-TPA type tumor promoters and their mechanism(s) in tumor promotion]
Carcinoma
2-difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice.
Carcinoma
2-substituted 3-(aminooxy)propanamines as inhibitors of ornithine decarboxylase: synthesis and biological activity.
Carcinoma
A Proposed Physiopathological Pathway to Hyperammonemic Encephalopathy in a Non-Cirrhotic Patient with Fibrolamellar Hepatocellular Carcinoma without Ornithine Transcarbamylase (OTC) Mutation.
Carcinoma
Activation of human squamous cell carcinoma ornithine decarboxylase activity by guanosine triphosphate.
Carcinoma
Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis.
Carcinoma
Analysis of ornithine decarboxylase messenger ribonucleic acid expression in colorectal carcinoma.
Carcinoma
Antimetastatic activity of DL-alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, in mice.
Carcinoma
Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents.
Carcinoma
Assessment of ornithine decarboxylase activity in rectal mucosa as a marker for colorectal adenomas and carcinomas.
Carcinoma
Chlorpheniramine inhibits the ornithine decarboxylase induction of Ehrlich carcinoma growing in vivo.
Carcinoma
Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and the proliferation of human breast cancer cell lines.
Carcinoma
Clinicopathological significance of cell cycle regulatory factors and differentiation-related factors in pancreatic neoplasms.
Carcinoma
Combined use of alpha-difluoromethylornithine and an inhibitor of S-adenosylmethionine decarboxylase in mice bearing P388 leukemia or Lewis lung carcinoma.
Carcinoma
Comparative antitumor properties in rodents of irreversible inhibitors of L-ornithine decarboxylase, used as such or as prodrugs.
Carcinoma
Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model.
Carcinoma
De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity.
Carcinoma
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase-alpha (GST)-alpha, GST-mu, and GST-pi.
Carcinoma
Development of difluoromethylornithine as a chemoprevention agent for the management of colon cancer.
Carcinoma
Differential inhibitory effects of three nitric oxide donors on ornithine decarboxylase activity in human colon carcinoma cells.
Carcinoma
Difluoromethylornithine-induced amplification of ornithine decarboxylase genes in Ehrlich ascites carcinoma cells.
Carcinoma
Effect of androgen on ornithine decarboxylase activity in androgen-dependent mouse mammary tumor (Shionogi Carcinoma 115) and its androgen-independent subline (CS 2).
Carcinoma
Effect of green tea extract on the induction of ornithine decarboxylase and the activation of extracellular signal-regulated kinase in bladder carcinoma ECV304 cells.
Carcinoma
Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis.
Carcinoma
Effect of tamoxifen and D,L-2-difluoromethylornithine on the growth, ornithine decarboxylase activity and polyamine content of mammary carcinomas induced by 1-methyl-1-nitrosourea.
Carcinoma
Effects of cyclosporine and alpha-difluoromethylornithine on the growth of mouse colon cancer in vitro.
Carcinoma
Effects of dose and duration of treatment with the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate on mouse skin carcinogenesis.
Carcinoma
Effects of urinary transferrin and ornithine decarboxylase-inducing fraction on rat bladder carcinogenesis.
Carcinoma
Effects of vasoactive intestinal peptide on adenosine 3',5'-monophosphate, ornithine decarboxylase, and cell growth in a human colon cell line.
Carcinoma
Enzyme regulation as an approach to interference with polyamine biosynthesis--an alternative to enzyme inhibition.
Carcinoma
Fluorine-19 NMR studies of tumor-bearing rats treated with difluoromethylornithine.
Carcinoma
Gallbladder mucosa ornithine decarboxylase activity is increased in patients with anomalous arrangement of the pancreaticobiliary duct.
Carcinoma
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line.
Carcinoma
Hepatocyte growth factor-activated NF-kappaB regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines.
Carcinoma
Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC.
Carcinoma
Identification of epidermal cell subpopulations with increased ornithine decarboxylase activity following treatment of murine epidermis with 12-O-tetradecanoylphorbol-13-acetate.
Carcinoma
Identification of epidermal growth factor as a component of the rat urinary bladder tumor-enhancing urinary fractions.
Carcinoma
Immunohistochemical detection of ornithine decarboxylase in individual cells: potential application for in vitro chemosensitivity assays.
Carcinoma
Increased expression of ornithine decarboxylase messenger RNA in human esophageal carcinoma.
Carcinoma
Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase.
Carcinoma
Induction of ornithine decarboxylase in normal and protein kinase C--depleted human colon carcinoma cells.
Carcinoma
Influence of gastrin, gastrin receptor blockers, epidermal growth factor, and difluoromethylornithine on the growth and the activity of ornithine decarboxylase of colonic carcinoma cells.
Carcinoma
Inhibition effect of miR-150 on the progression of oral squamous cell carcinoma by data analysis model based on independent sample T-test.
Carcinoma
Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice.
Carcinoma
Inhibition of polyamine oxidase improves the antitumoral effect of ornithine decarboxylase inhibitors.
Carcinoma
Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine.
Carcinoma
Inhibitory effects of soy isoflavones on rat prostate carcinogenesis induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Carcinoma
Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment.
Carcinoma
Intracellular localization of ornithine decarboxylase and its regulatory protein, antizyme-1.
Carcinoma
Involvement of protein kinase C in the transcriptional regulation of ornithine decarboxylase gene expression by 12-O-tetradecanoylphorbol-13-acetate in T24 human bladder carcinoma cells.
Carcinoma
Levels of activity of the polyamine biosynthetic decarboxylases as indicators of degree of malignancy of human cutaneous epitheliomas.
Carcinoma
Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor.
Carcinoma
Modified responses to PGE2 in polyamine biosynthesis by T lymphocytes of gastric- and conjunctiva basal cell-carcinoma patients.
Carcinoma
Mouse and human ornithine decarboxylase genes. Methylation polymorphism and amplification.
Carcinoma
Multiple promoter elements govern expression of the human ornithine decarboxylase gene in colon carcinoma cells.
Carcinoma
Ornithine decarboxylase activity in tumor and normal tissue of head and neck cancer patients.
Carcinoma
Ornithine decarboxylase activity, prolactin blood levels, and estradiol and progesterone receptors in human breast cancer.
Carcinoma
Ornithine decarboxylase and diamine oxidase in human colon carcinoma cell line CaCo-2 in culture.
Carcinoma
Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.
Carcinoma
Ornithine decarboxylase is directly involved in mouse mammary carcinoma cell invasion in vitro.
Carcinoma
Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis.
Carcinoma
Polyamine deprivation-induced enhanced uptake of methylglyoxal bis(guanylhydrazone) by tumor cells.
Carcinoma
Polyamine levels and ODC activity in intestinal-type and diffuse-type gastric carcinoma.
Carcinoma
Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.
Carcinoma
Polyamines and their biosynthetic enzymes in Ehrlich ascites-carcinoma cells. Modification of tumour polyamine pattern by diamines.
Carcinoma
Polyamines are necessary for the survival of human small-cell lung carcinoma in culture.
Carcinoma
Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters.
Carcinoma
Prostate cancer chemoprevention by green tea: in vitro and in vivo inhibition of testosterone-mediated induction of ornithine decarboxylase.
Carcinoma
Regulation by 1,4-diamines of the ornithine decarboxylase activity induced by ornithine in perifused tumor cells.
Carcinoma
Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis.
Carcinoma
Regulation of putrescine metabolism in Ehrlich ascites carcinoma cells exposed to hypotonic medium.
Carcinoma
Spermidine/spermine N1-acetyltransferase, a new biochemical marker for epithelial proliferation in rat bladder.
Carcinoma
Studies on ornithine decarboxylase from liver, kidney and tumoral tissues during activity decay following cycloheximide administration.
Carcinoma
Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice.
Carcinoma
Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis.
Carcinoma
Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression.
Carcinoma
The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells--In vitro.
Carcinoma
The effects of Chinese drugs for supporting healthy energy and removing blood stasis on postoperative metastasis of gastric carcinoma and ornithine decarboxylase.
Carcinoma
The heterotopically transplanted rat urinary bladder as a model for detection of tumor-promoting urinary growth factor(s).
Carcinoma
The induction of ornithine decarboxylase by ornithine takes place at post-transcriptional level in perifused Ehrlich carcinoma cells.
Carcinoma
TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma.
Carcinoma
Treatment of metastatic Lewis lung carcinoma with DL-alpha-difluoromethylornithine.
Carcinoma
Tumor necrosis factor stimulates ornithine decarboxylase activity in human fibroblasts and tumor target cells.
Carcinoma
Tumour effect on arginine/ornithine metabolic relationship in hypertrophic mouse kidney.
Carcinoma
Tumourigenicity, cell-surface glycoprotein changes and ornithine decarboxylase gene pattern in Ehrlich ascites-carcinoma cells.
Carcinoma
Upregulation of ornithine decarboxylase mRNA expression in Barrett's esophagus and Barrett's-associated adenocarcinoma.
Carcinoma
Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5'-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma.
Carcinoma
[Gene expression profiling of human ovarian epithelial tumors by digo nucleotide microarray]
Carcinoma
[Ornithine decarboxylase activity and polyamine levels in human thyroid tumor tissue]
Carcinoma
[Reversion of malignant phenotypes of human lung squamous carcinoma cells by ornithine decarboxylase antisense RNA]
Carcinoma
[The influence of theophylline on polyamine metabolism and colonic carcinogenesis induced by 1.2-dimethylhydrazine in mice]
Carcinoma, Basal Cell
Immunohistochemical localization of ornithine decarboxylase in skin tumors.
Carcinoma, Basal Cell
Levels of activity of the polyamine biosynthetic decarboxylases as indicators of degree of malignancy of human cutaneous epitheliomas.
Carcinoma, Basal Cell
Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.
Carcinoma, Bronchogenic
Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers.
Carcinoma, Ehrlich Tumor
Cell cycle phase-dependent induction of ornithine decarboxylase-antizyme.
Carcinoma, Ehrlich Tumor
Control by hyperthermia of ornithine decarboxylase in Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Control by treatment with lithium chloride of ornithine decarboxylase in Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Cytocidal effect of alpha-methylornithine, a competitive inhibitor of ornithine decarboxylase, on ehrlich ascites tumor cells in vivo.
Carcinoma, Ehrlich Tumor
Effect of acylated derivatives of ascorbate on ornithine decarboxylase induction in Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Ehrlich ascites tumour cells become refractory to alpha-difluoromethylornithine at a certain stage of growth.
Carcinoma, Ehrlich Tumor
Growth inhibitory effect of green tea extract in Ehrlich ascites tumor cells involves cytochrome c release and caspase activation.
Carcinoma, Ehrlich Tumor
Histamine and serotonin inhibit induction of ornithine decarboxylase by ornithine in perifused Ehrlich ascites tumour cells.
Carcinoma, Ehrlich Tumor
Implications for a reduced DNA-elongation rate in polyamine-depleted cells.
Carcinoma, Ehrlich Tumor
Inhibition of ornithine decarboxylase activity and cell growth by diamines: a comparison between the effects of two homologs, 1,3-diaminopropane and 1,4-diaminobutane (putrescine).
Carcinoma, Ehrlich Tumor
Irreversible inhibition of the early increase in ornithine decarboxylase activity following growth stimulation is required to block Ehrlich ascites tumor cell proliferation in culture.
Carcinoma, Ehrlich Tumor
Mechanisms mediating metabolic abnormalities in the livers of Ehrlich ascites tumor-bearing mice.
Carcinoma, Ehrlich Tumor
Ornithine decarboxylase inhibitors increase the cellular content of the enzyme: implications for translational regulation.
Carcinoma, Ehrlich Tumor
Regulation of ornithine decarboxylase during cell growth. Changes in the stability and translatability of the mRNA, and in the turnover of the protein.
Carcinoma, Ehrlich Tumor
Reversal of the growth inhibitory effect of alpha-difluoromethylornithine by putrescine but not by other divalent cations.
Carcinoma, Ehrlich Tumor
Superinduction of ornithine decarboxylase (ODC) by actinomycin D is due to stimulation of ODC mRNA translation.
Carcinoma, Embryonal
alpha-Difluoromethylornithine induces differentiation of a human embryonal carcinoma cell line in vitro.
Carcinoma, Embryonal
Induction of F9 embryonal carcinoma cell differentiation by inhibition of polyamine synthesis.
Carcinoma, Embryonal
Inhibition of ornithine decarboxylase by retinoic acid and difluoromethylornithine in relation to their effects on differentiation and proliferation.
Carcinoma, Embryonal
Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation.
Carcinoma, Embryonal
The response of several murine embryonal carcinoma cell lines to stimulation of differentiation by alpha-difluoromethylornithine.
Carcinoma, Hepatocellular
A role for ornithine in the regulation of putrescine accumulation and ornithine decarboxylase activity in Reuber H35 hepatoma cells.
Carcinoma, Hepatocellular
Abnormal accumulation and toxicity of polyamines in a difluoromethylornithine-resistant HTC cell variant.
Carcinoma, Hepatocellular
Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.
Carcinoma, Hepatocellular
Analogues of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site.
Carcinoma, Hepatocellular
Analysis of ODC and c-myc gene expression in hepatocellular carcinoma by in situ hybridization and immunohistochemistry.
Carcinoma, Hepatocellular
Asparagine transport and the induction of ornithine decarboxylase in H-35 rat hepatoma cells.
Carcinoma, Hepatocellular
Azo dye-induced alterations in vitamin B-6 metabolism and in pyridoxal 5'-phosphate-binding proteins in rat liver.
Carcinoma, Hepatocellular
Characterization of Ca(2+) flows essential in ornithine decarboxylase induction by L-asparagine in rat hepatoma cells using Ca(2+) flow inhibitors.
Carcinoma, Hepatocellular
Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells.
Carcinoma, Hepatocellular
Cloning and expression of two ornithine decarboxylase forms from HMOA cells.
Carcinoma, Hepatocellular
Cloning and nucleotide sequence of rat ornithine decarboxylase cDNA.
Carcinoma, Hepatocellular
Comparison of ornithine decarboxylase from rat liver, rat hepatoma and mouse kidney.
Carcinoma, Hepatocellular
Consequences of aberrant ornithine decarboxylase regulation in rat hepatoma cells.
Carcinoma, Hepatocellular
Cultured hepatoma cells for the study of enzyme regulation: induction of ornithine decarboxylase by insulin and asparagine.
Carcinoma, Hepatocellular
Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells.
Carcinoma, Hepatocellular
Destabilization of ornithine decarboxylase by transfected antizyme gene expression in hepatoma tissue culture cells.
Carcinoma, Hepatocellular
Detection of ornithine decarboxylase messenger RNA in human hepatocellular carcinoma by in situ hybridization.
Carcinoma, Hepatocellular
Differences in the mode of regulation of ornithine decarboxylase and tyrosine aminotransferase in H-35 rat hepatoma cells shown by varying the medium composition.
Carcinoma, Hepatocellular
Effect of alpha-methyl ornithine on ornithine decarboxylase activity of rat hepatoma cells in culture.
Carcinoma, Hepatocellular
Effect of calvatic acid and its analogs on ornithine decarboxylase activity in tumour cells.
Carcinoma, Hepatocellular
Effect of GABA and isogabaculine on ornithine decarboxylase and putrescine metabolism.
Carcinoma, Hepatocellular
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
Carcinoma, Hepatocellular
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. II. Effect of serum and insulin.
Carcinoma, Hepatocellular
Effect of growth conditions on the ornithine decarboxylase activity of rat hepatoma cells.
Carcinoma, Hepatocellular
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Carcinoma, Hepatocellular
Excess putrescine accumulation inhibits the formation of modified eukaryotic initiation factor 5A (eIF-5A) and induces apoptosis.
Carcinoma, Hepatocellular
Expression patterns of ornithine decarboxylase and c-met in growing Yoshida AH-130 hepatoma.
Carcinoma, Hepatocellular
Genetic alterations of the ornithine decarboxylase gene in human colorectal cancers.
Carcinoma, Hepatocellular
Growth state-dependent alterations in the ability of 12-O-tetradecanoylphorbol-13-acetate to increase ornithine decarboxylase activity in Reuber h35 Hepatoma cells.
Carcinoma, Hepatocellular
Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism.
Carcinoma, Hepatocellular
Hepatocyte growth factor-induced expression of ornithine decarboxylase, c-met, and c-myc is differently affected by protein kinase inhibitors in human hepatoma cells HepG2.
Carcinoma, Hepatocellular
Increased ornithine decarboxylase activity in cultured cells exposed to low energy modulated microwave fields and phorbol ester tumor promoters.
Carcinoma, Hepatocellular
Independent actions of asparagine and high levels of free Ca2+ in the induction of ornithine decarboxylase.
Carcinoma, Hepatocellular
Induction of hepatic ornithine decarboxylase by hypolipidemic drugs with hepatic peroxisome proliferative activity.
Carcinoma, Hepatocellular
Induction of ornithine decarboxylase in Reuber H35 rat hepatoma cells.
Carcinoma, Hepatocellular
Inhibition of ornithine decarboxylase by the isomers of 1,4-dimethylputrescine.
Carcinoma, Hepatocellular
Insulin action in normal and protein kinase C-deficient rat hepatoma cells. Effects on protein phosphorylation, protein kinase activities, and ornithine decarboxylase activities and messenger ribonucleic acid levels.
Carcinoma, Hepatocellular
Insulin and phorbol myristic acetate induce ornithine decarboxylase in Reuber H35 rat hepatoma cells by different mechanisms.
Carcinoma, Hepatocellular
Involvement of protein kinase C in the regulation of ornithine decarboxylase mRNA by phorbol esters in rat hepatoma cells.
Carcinoma, Hepatocellular
Involvement of the proteasome and antizyme in ornithine decarboxylase degradation by a reticulocyte lysate.
Carcinoma, Hepatocellular
Loss of intracellular putrescine pool-size regulation induces apoptosis.
Carcinoma, Hepatocellular
Marked and prolonged inhibition of mammalian ornithine decarboxylase in vivo by esters of (E)-2-(fluoromethyl)dehydroornithine.
Carcinoma, Hepatocellular
Mechanism-based in vitro screening of potential cancer chemopreventive agents.
Carcinoma, Hepatocellular
Modulation of insulin induced ornithine decarboxylase by putrescine and methylputrescines in H-35 hepatoma cells.
Carcinoma, Hepatocellular
Ornithine decarboxylase activity and DNA synthesis in Morris hepatomas 5123-C and 7800.
Carcinoma, Hepatocellular
Ornithine decarboxylase activity in the non-cancerous hepatic tissue of patients with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Ornithine decarboxylase from hepatoma cells and a variant cell line in which the enzyme is more stable.
Carcinoma, Hepatocellular
Ornithine decarboxylase lability in 2 transplantable highly deviated rat hepatomas.
Carcinoma, Hepatocellular
Permanent decrease in activity of ornithine decarboxylase antizyme in rat liver during chemical hepatocarcinogenesis.
Carcinoma, Hepatocellular
Plasmodium berghei: inhibitors of ornithine decarboxylase block exoerythrocytic schizogony.
Carcinoma, Hepatocellular
Point mutation of ornithine decarboxylase gene in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Point mutations of ornithine decarboxylase gene are an infrequent event in colorectal cancer but a missense mutation was found in a replication error positive patient with hMSH2 germline mutation.
Carcinoma, Hepatocellular
Polyamine metabolism and recurrence after resection for hepatocellular carcinoma.
Carcinoma, Hepatocellular
Proteasome pathway operates for the degradation of ornithine decarboxylase in intact cells.
Carcinoma, Hepatocellular
Putrescine-stimulated intracellular Ca2+ release for invasiveness of rat ascites hepatoma cells.
Carcinoma, Hepatocellular
Reduction by interferon-alpha of levels of c-myc protein and DNA synthesis in a human hepatoma cell line mediated by inhibition of putrescine synthesis.
Carcinoma, Hepatocellular
Regulation of ornithine decarboxylase mRNA by phorbol esters and insulin in normal and C-kinase-deficient rat hepatoma cells.
Carcinoma, Hepatocellular
Regulation of polyamine biosynthesis in rat hepatoma (HTC) cells by a bisbenzyl polyamine analogue.
Carcinoma, Hepatocellular
Regulatory interrelations between GABA and polyamines. II. Effect of GABA on ornithine decarboxylase and putrescine levels in cell culture.
Carcinoma, Hepatocellular
Relationship between Ca2+ and L-asparagine in the induction of ornithine decarboxylase in H-35 rat hepatoma cells.
Carcinoma, Hepatocellular
Relationship between ornithine decarboxylase gene abnormalities and human hepatocarcinogenesis.
Carcinoma, Hepatocellular
Relationship of ornithine decarboxylase activity and histological findings in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Relative in vitro stability of ornithine decarboxylase from liver preneoplastic nodules and hepatomas.
Carcinoma, Hepatocellular
Retraction notice to "Hepatocyte growth factor-induced expression of ornithine decarboxylase, c-met,and c-mycIs differently affected by protein kinase inhibitors in human hepatoma cells HepG2" [Exp. Cell Res. 242 (1998) 401-409].
Carcinoma, Hepatocellular
Retraction Notice to "Hepatocyte growth factor-induced expression of ornithine decarboxylase, c-met,and c-mycIs differently affected by protein kinase inhibitors in human hepatoma cells HepG2" [Exp. Cell Res. 242 (1998) 401-409].
Carcinoma, Hepatocellular
Reversed-phase ion-pair liquid chromatographic procedure for the simultaneous analysis of S-adenosylmethionine, its metabolites and the natural polyamines.
Carcinoma, Hepatocellular
Role of activation of ornithine decarboxylase and DNA synthesis on ethynylestradiol-induced hepatocarcinogenesis.
Carcinoma, Hepatocellular
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
Carcinoma, Hepatocellular
Single amino-acid replacement is responsible for the stabilization of ornithine decarboxylase in HMOA cells.
Carcinoma, Hepatocellular
Spermine inhibits induction of ornithine decarboxylase by cyclic AMP but not by dexamethasone in rat hepatoma cells.
Carcinoma, Hepatocellular
Stable ornithine decarboxylase in a rat hepatoma cell line selected for resistance to alpha-difluoromethylornithine.
Carcinoma, Hepatocellular
Stimulation of ornithine decarboxylase synthesis and its control by polyamines in regenerating rat liver and cultured rat hepatoma cells.
Carcinoma, Hepatocellular
Studies on ornithine decarboxylase from liver, kidney and tumoral tissues during activity decay following cycloheximide administration.
Carcinoma, Hepatocellular
Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase.
Carcinoma, Hepatocellular
Targeting ODC1 inhibits tumor growth through reduction of lipid metabolism in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures.
Carcinoma, Hepatocellular
The effects of low-energy 60-Hz environmental electromagnetic fields upon the growth-related enzyme ornithine decarboxylase.
Carcinoma, Hepatocellular
The induction of ornithine decarboxylase by tumor promoting phorbol ester analogues in Reuber H35 hepatoma cells.
Carcinoma, Hepatocellular
The induction of ornithine decarboxylase in cultured hepatoma cells.
Carcinoma, Hepatocellular
Transcription factor Sp3 antagonizes activation of the ornithine decarboxylase promoter by Sp1.
Carcinoma, Hepatocellular
Transient induction of ornithine decarboxylase mRNA in rat hepatoma cells treated with 12-O-tetradecanoylphorbol-13-acetate.
Carcinoma, Hepatocellular
Two distinct mechanisms for ornithine decarboxylase regulation by polyamines in rat hepatoma cells.
Carcinoma, Hepatocellular
Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5'-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma.
Carcinoma, Hepatocellular
[DNA vaccine encoding alpha-fetoprotein with fused ornithine decarboxylase degradation signal significantly suppresses hepatocellular carcinoma growth in mice].
Carcinoma, Hepatocellular
[Fluorometric method of determining the activity of ornithine decarboxylase from animal tissues]
Carcinoma, Lewis Lung
Antimetastatic activity of DL-alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, in mice.
Carcinoma, Lewis Lung
Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents.
Carcinoma, Lewis Lung
Combined use of alpha-difluoromethylornithine and an inhibitor of S-adenosylmethionine decarboxylase in mice bearing P388 leukemia or Lewis lung carcinoma.
Carcinoma, Lewis Lung
Comparative antitumor properties in rodents of irreversible inhibitors of L-ornithine decarboxylase, used as such or as prodrugs.
Carcinoma, Lewis Lung
Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis.
Carcinoma, Lewis Lung
Inhibition of polyamine oxidase improves the antitumoral effect of ornithine decarboxylase inhibitors.
Carcinoma, Non-Small-Cell Lung
In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells.
Carcinoma, Renal Cell
Chemoprevention and chemotherapy by inhibition of ornithine decarboxylase activity and polyamine synthesis: colonic, pancreatic, mammary, and renal carcinomas.
Carcinoma, Renal Cell
Effects of alpha-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) on the growth of experimental renal adenocarcinoma in mice.
Carcinoma, Renal Cell
Effects of alpha-difluoromethylornithine on the growth of experimental Wilms' tumor and renal adenocarcinoma.
Carcinoma, Renal Cell
Experimental chemotherapy in a transplantable renal adenocarcinoma. I: Effects of some inhibitors of polyamine synthesis.
Carcinoma, Renal Cell
Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment.
Carcinoma, Renal Cell
Ornithine decarboxylase activity and polyamine content in normal renal tissue and in renal carcinoma.
Carcinoma, Small Cell
Enzyme regulation as an approach to interference with polyamine biosynthesis--an alternative to enzyme inhibition.
Carcinoma, Small Cell
Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis.
Carcinoma, Squamous Cell
Activation of human squamous cell carcinoma ornithine decarboxylase activity by guanosine triphosphate.
Carcinoma, Squamous Cell
Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC.
Carcinoma, Squamous Cell
Immunohistochemical localization of ornithine decarboxylase in skin tumors.
Carcinoma, Squamous Cell
Increased expression of ornithine decarboxylase messenger RNA in human esophageal carcinoma.
Carcinoma, Squamous Cell
Inhibitory regulation of serum factor(s)-caused ornithine decarboxylase induction by the protein kinase C system in A431 human epidermoid carcinoma cells.
Carcinoma, Squamous Cell
Levels of activity of the polyamine biosynthetic decarboxylases as indicators of degree of malignancy of human cutaneous epitheliomas.
Carcinoma, Squamous Cell
Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor.
Carcinoma, Squamous Cell
Ornithine decarboxylase activity in tumor and normal tissue of head and neck cancer patients.
Carcinoma, Squamous Cell
Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice.
Carcinoma, Squamous Cell
Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.
Carcinoma, Squamous Cell
[Reversion of malignant phenotypes of human lung squamous carcinoma cells by ornithine decarboxylase antisense RNA]
Carcinoma, Transitional Cell
Spermidine/spermine N1-acetyltransferase, a new biochemical marker for epithelial proliferation in rat bladder.
Carcinoma, Transitional Cell
TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma.
Cardiomegaly
A study of cardiac effects of thyroid hormones: evidence for amelioration of the effects of thyroxine by sodium ipodate.
Cardiomegaly
Catecholamine-thyroid hormone interaction on myocardial ornithine decarboxylase.
Cardiomegaly
Effect of captopril on isoproterenol-induced myocardial ornithine decarboxylase activity.
Cardiomegaly
Effect of losartan, an AT1 selective angiotensin II receptor antagonist, on isoproterenol-induced cardiac ornithine decarboxylase activity.
Cardiomegaly
Evidence that AMP-activated protein kinase can negatively modulate Ornithine decarboxylase activity in cardiac myoblasts.
Cardiomegaly
Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy.
Cardiomegaly
Overexpression of ornithine decarboxylase decreases ventricular systolic function during induction of cardiac hypertrophy.
Cardiomegaly
Regional changes in ornithine decarboxylase activity and polyamine levels during thyroxine-induced cardiac hypertrophy.
Cardiomegaly
Responses of heart ornithine decarboxylase and adrenal catecholamines to methadone and sympathetic stimulants in developing and adults rats.
Cardiomegaly
Role of polyamines in isoproterenol-induced cardiac hypertrophy: effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase.
Cardiomegaly
Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy.
Cardiomegaly
The induction of cardiac hypertrophy by catecholamines can be dissociated from their inotropic effect.
Cardiomegaly
The induction of cardiac ornithine decarboxylase by ?2-adrenergic agents is associated with calcium channels and phosphorylation of ERK1/2.
Cardiotoxicity
Acute effects of cocaine on ornithine decarboxylase activity in fetal and neonatal rat heart: evidence for cardiotoxicity.
Cardiovascular Diseases
Exercise training preserves ischemic preconditioning in aged rat hearts by restoring the myocardial polyamine pool.
Cell Transformation, Neoplastic
Loss of p27Kip1 from cyclin E/cyclin-dependent kinase (CDK) 2 but not from cyclin D1/CDK4 complexes in cells transformed by polyamine biosynthetic enzymes.
Cell Transformation, Neoplastic
TGFalpha is required for full expression of the transformed growth phenotype of NIH 3T3 cells overexpressing ornithine decarboxylase.
Central Nervous System Infections
In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors.
Central Nervous System Neoplasms
Degrees of malignancy in human primary central nervous system tumors: ornithine decarboxylase levels as better indicators than adenosylmethionine decarboxylase levels.
Cerebral Infarction
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Cervical Intraepithelial Neoplasia
Effects of difluoromethylornithine on growth inhibition and apoptosis in human cervical epithelial and cancerous cell lines.
Cervical Intraepithelial Neoplasia
Epidermal growth factor receptor expression in cervical intraepithelial neoplasia and its modulation during an alpha-difluoromethylornithine chemoprevention trial.
Cervical Intraepithelial Neoplasia
Phase I dose de-escalation trial of alpha-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia.
Chagas Disease
Trypanosoma cruzi as a model system to study the expression of exogenous genes coding for polyamine biosynthetic enzymes. Induction of DFMO resistance in transgenic parasites.
Chagas Disease
Trypanosoma cruzi Coexpressing Ornithine Decarboxylase and Green Fluorescence Proteins as a Tool to Study the Role of Polyamines in Chagas Disease Pathology.
Chagas Disease
Trypanosoma cruzi epimastigotes lack ornithine decarboxylase but can express a foreign gene encoding this enzyme.
Cholecystitis
Ornithine decarboxylase and glutamate decarboxylase 65 as prognostic markers of gallbladder malignancy: a clinicopathological study in benign and malignant lesions of the gallbladder.
Cholecystitis, Acute
Routine surveillance cholangiography after percutaneous cholecystostomy delays drain removal and cholecystectomy.
Cholera
Effects of cell surface receptor-altering agents on the binding and biological activity of 12-O-tetradecanoylphorbol-13-acetate in isolated epidermal cells.
Cholera
Effects of cholera and pertussis toxins on prolactin stimulation of lactose synthesis and ornithine decarboxylase activity in mouse mammary gland explants.
Cholera
Effects of cholera toxin on thyroid cyclic AMP-dependent protein kinase and ornithine decarboxylase activities.
Cholera
Effects of luminal stimuli on polyamine metabolism in the small intestine of the rat: the role of enteric nerves.
Cholera
Effects of parathyroid hormone on ornithine decarboxylase activity in human osteosarcoma cells.
Cholera
Enhancement by 3-isobutyl-1-methylxanthine and cholera toxin of 12-O-tetradecanoylphorbol-13-acetate-stimulated cyclic nucleotide levels and ornithine decarboxylase activity in isolated epidermal cells.
Cholera
Genetic evidence that a phorbol ester tumor promoter stimulates ornithine decarboxylase activity by a pathway that is independent of cyclic AMP-dependent protein kinases in CHO cells.
Cholera
Inhibition of ornithine decarboxylase and S-adenosylmethionine decarboxylase activities of S49 lymphoma cells by agents increasing cyclic AMP.
Cholera
Synergistic induction of ornithine decarboxylase by diacylglycerol, A23187, and cholera toxin in guinea pig lymphocytes.
Cholera
The role of cAMP in the induction of ornithine decarboxylase by nerve and epidermal growth factors.
Choline Deficiency
Effects of the irreversible ornithine decarboxylase inhibitor, alpha-difluoromethylornithine, aflatoxin B1, and choline deficiency on hepatocarcinogenesis.
Choriocarcinoma
Polyamines control human chorionic gonadotropin production in the JEG-3 choriocarcinoma cell.
Cleft Palate
Effect of D,L-alpha-difluoromethyl ornithine on cleft palate induced by the TCDD congener, 3,3',4,4'-tetrachloroazoxybenzene, in the fetuses of mice.
Coccidioidomycosis
Sequence, expression and functional analysis of the Coccidioides immitis ODC (ornithine decarboxylase) gene.
Cockayne Syndrome
Essential role of polyamines in restoration of DNA synthesis after UV radiation and expression of UV resistance in Cockayne syndrome cells.
Colitis
DNA microarray technology reveals similar gene expression patterns in rats with vitamin a deficiency and chemically induced colitis.
Colitis
Efficacy of glutamine-enriched enteral nutrition in an experimental model of mucosal ulcerative colitis.
Colitis
Immunohistochemical expression of ornithine decarboxylase, diamine oxidase, putrescine, and spermine in normal canine enterocolic mucosa, in chronic colitis, and in colorectal cancer.
Colitis
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Colitis
Troglitazone, a ligand for peroxisome proliferator-activated receptor gamma, inhibits chemically-induced aberrant crypt foci in rats.
Colitis, Ulcerative
Colonic ornithine decarboxylase in inflammatory bowel disease: ileorectal activity gradient, guanosine triphosphate stimulation, and association with epithelial regeneration but not the degree of inflammation and clinical features.
Colitis, Ulcerative
Increased colonic ornithine decarboxylase activity in inflammatory bowel disease in children.
Colitis, Ulcerative
Ornithine decarboxylase in colonic mucosa from patients with moderate or severe Crohn's disease and ulcerative colitis.
Colitis, Ulcerative
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Colonic Neoplasms
A protective role of 1,25-dihydroxyvitamin D3 in chemically induced rat colon carcinogenesis.
Colonic Neoplasms
A randomized, placebo-controlled trial of low-dose alpha-difluoromethylornithine in individuals at risk for colorectal cancer.
Colonic Neoplasms
Apigenin Inhibits Human SW620 Cell Growth by Targeting Polyamine Catabolism.
Colonic Neoplasms
beta-Carotene inhibits rectal mucosal ornithine decarboxylase activity in colon cancer patients.
Colonic Neoplasms
Bile acids, ornithine decarboxylase, and cell proliferation in colon cancer: a review.
Colonic Neoplasms
Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis.
Colonic Neoplasms
Chemopreventive effect of chitosan oligosaccharide against colon carcinogenesis.
Colonic Neoplasms
Chemopreventive effects of calcium but not aspirin supplementation in cholic acid-promoted colon carcinogenesis: correlation with intermediate endpoints.
Colonic Neoplasms
Chemopreventive effects of polysaccharides extract from Asterina pectinifera on HT-29 human colon adenocarcinoma cells.
Colonic Neoplasms
Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos.
Colonic Neoplasms
Clinical application of a novel DNA fluorescence intercalator, pyrylium dye, for the quantification of PCR products.
Colonic Neoplasms
Cloning and expression of ornithine decarboxylase gene from human colorectal carcinoma.
Colonic Neoplasms
Colon ornithine decarboxylase activity following standard endoscopy preparation regimens.
Colonic Neoplasms
Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth.
Colonic Neoplasms
Effect of chemopreventive agents on intermediate biomarkers during different stages of azoxymethane-induced colon carcinogenesis.
Colonic Neoplasms
Effect of chemopreventive agents on posttranslational plasmamembrane association of ras-p21 during chemoprevention of azoxymethane-induced colon carcinogenesis.
Colonic Neoplasms
Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models.
Colonic Neoplasms
Effects of gastrin and difluoromethylornithine on growth of human colon cancer.
Colonic Neoplasms
Estradiol is trophic for colon cancer in mice: effect on ornithine decarboxylase and c-myc messenger RNA.
Colonic Neoplasms
Expression of c-myb protooncogene and other cell cycle-related genes in normal and neoplastic human colonic mucosa.
Colonic Neoplasms
Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells.
Colonic Neoplasms
Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.
Colonic Neoplasms
Hydroxylamine-containing inhibitors of polyamine biosynthesis and impairment of colon cancer cell growth.
Colonic Neoplasms
Increased levels of phorbin, c-myc, and ornithine decarboxylase RNAs in human colon cancer.
Colonic Neoplasms
Increased translation efficiency and antizyme-dependent stabilization of ornithine decarboxylase in amino acid-supplemented human colon adenocarcinoma cells, Caco-2.
Colonic Neoplasms
Induction of ornithine decarboxylase in normal and protein kinase C--depleted human colon carcinoma cells.
Colonic Neoplasms
Intermediate biomarkers of colon cancer: modulation of expression of ras oncogene by chemopreventive agents during azoxymethane induced colon carcinogenesis.
Colonic Neoplasms
Involvement of ornithine decarboxylase in the control of proliferation of the HT29 human colon cancer cell line. Effect of vasoactive intestinal peptide on enzyme activity.
Colonic Neoplasms
Levels of colorectal ornithine decarboxylase activity in patients with colon cancer, a family history of nonpolyposis hereditary colorectal cancer, and adenomas.
Colonic Neoplasms
Metabolomics of adherent mammalian cells by capillary electrophoresis-mass spectrometry: HT-29 cells as case study.
Colonic Neoplasms
Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells.
Colonic Neoplasms
Multiple promoter elements govern expression of the human ornithine decarboxylase gene in colon carcinoma cells.
Colonic Neoplasms
Nonsteroidal anti-inflammatory drugs stimulate spermidine/spermine acetyltransferase and deplete polyamine content in colon cancer cells.
Colonic Neoplasms
Ornithine decarboxylase activity as a biochemical marker in individuals predisposed to lung cancer.
Colonic Neoplasms
Ornithine decarboxylase activity is inhibited by the polyamine precursor amino acids at the protein stability level in Caco-2 cells.
Colonic Neoplasms
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Colonic Neoplasms
Ornithine decarboxylase levels in the rectal mucosa of patients with colonic neoplasia.
Colonic Neoplasms
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
Colonic Neoplasms
Persistence of the circadian variation and altered response to hepatectomy of hepatic ornithine decarboxylase activity with malignant tumor burden.
Colonic Neoplasms
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
Colonic Neoplasms
Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer.
Colonic Neoplasms
Polyamine levels, ornithine decarboxylase (ODC) activity, and ODC-mRNA expression in normal and cancerous human colonocytes.
Colonic Neoplasms
Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.
Colonic Neoplasms
Properties of ornithine decarboxylase in human colorectal adenocarcinomas.
Colonic Neoplasms
Reduced expression of phospholipase C-delta, a signal-transducing enzyme, in rat colon neoplasms induced by methylazoxymethanol acetate.
Colonic Neoplasms
Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventive agent.
Colonic Neoplasms
Role of calcium in the regulation of ornithine decarboxylase enzyme activity in mouse colon cancer cells.
Colonic Neoplasms
Systemic alterations in ornithine decarboxylase activity caused by colon cancer in mice.
Colonic Neoplasms
ZBP-99 defines a conserved family of transcription factors and regulates ornithine decarboxylase gene expression.
Colonic Neoplasms
[A study of ornithine decarboxylase activity in tumor tissue and rectal mucosa in patients with colorectal cancer or adenoma]
Colorectal Neoplasms
A comprehensive strategy to combat colon cancer targeting the adenomatous polyposis coli tumor suppressor gene.
Colorectal Neoplasms
Absence of effect of supplemental oral calcium on ornithine decarboxylase (ODC) activity in colonic mucosae of healthy individuals with a family history of colorectal cancer.
Colorectal Neoplasms
Adenovirus-mediated expression of both antisense ODC and AdoMetDC inhibited colorectal cancer cell growth in vitro.
Colorectal Neoplasms
Adenovirus-mediated expression of both antisense ornithine decarboxylase and s-adenosylmethionine decarboxylase induces G1 arrest in HT-29 cells.
Colorectal Neoplasms
Alpha-difluoromethylornithine-induced inhibition of growth of autochthonous experimental colonic tumors produced by azoxymethane in male F344 rats.
Colorectal Neoplasms
Analysis of ornithine decarboxylase messenger ribonucleic acid expression in colorectal carcinoma.
Colorectal Neoplasms
Arginine Metabolism and Its Potential in Treatment of Colorectal Cancer.
Colorectal Neoplasms
Association between high levels of ornithine decarboxylase activity and favorable prognosis in human colorectal carcinoma.
Colorectal Neoplasms
Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival.
Colorectal Neoplasms
Cloning and expression of ornithine decarboxylase gene from human colorectal carcinoma.
Colorectal Neoplasms
Colon ornithine decarboxylase activity following standard endoscopy preparation regimens.
Colorectal Neoplasms
Colorectal ornithine decarboxylase activity in human mucosa and tumors: elevation of enzymatic activity in distal mucosa.
Colorectal Neoplasms
Failure of rectal ornithine decarboxylase to identify adenomatous polyp status.
Colorectal Neoplasms
Genetic alterations of the ornithine decarboxylase gene in human colorectal cancers.
Colorectal Neoplasms
Genetic and biochemical changes in colorectal carcinoma in relation to morphologic characteristics.
Colorectal Neoplasms
Immunohistochemical expression of ornithine decarboxylase, diamine oxidase, putrescine, and spermine in normal canine enterocolic mucosa, in chronic colitis, and in colorectal cancer.
Colorectal Neoplasms
Immunohistochemical staining and activity of ornithine decarboxylase in colorectal cancer.
Colorectal Neoplasms
Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-?/Smad signaling pathway.
Colorectal Neoplasms
L-arginine reduces cell proliferation and ornithine decarboxylase activity in patients with colorectal adenoma and adenocarcinoma.
Colorectal Neoplasms
Lentiviral vector-mediated downregulation of ornithine decarboxylase inhibits tumor cell growth in vitro and in vivo.
Colorectal Neoplasms
Levels of colorectal ornithine decarboxylase activity in patients with colon cancer, a family history of nonpolyposis hereditary colorectal cancer, and adenomas.
Colorectal Neoplasms
Meat consumption, ornithine decarboxylase gene polymorphism, and outcomes after colorectal cancer diagnosis.
Colorectal Neoplasms
Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines.
Colorectal Neoplasms
Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes.
Colorectal Neoplasms
Ornithine decarboxylase activity as a prognostic marker for colorectal cancer.
Colorectal Neoplasms
Ornithine decarboxylase activity in hepatic and extrahepatic metastases from colorectal cancer.
Colorectal Neoplasms
Ornithine decarboxylase and polyamines in colorectal neoplasia and mucosa.
Colorectal Neoplasms
Ornithine decarboxylase gene is overexpressed in colorectal carcinoma.
Colorectal Neoplasms
Point mutations of ornithine decarboxylase gene are an infrequent event in colorectal cancer but a missense mutation was found in a replication error positive patient with hMSH2 germline mutation.
Colorectal Neoplasms
Polyamine biosynthesis in relation to K-ras and p-53 mutations in colorectal carcinoma.
Colorectal Neoplasms
Polyamine depletion by ODC-AdoMetDC antisense adenovirus impairs human colorectal cancer growth and invasion in vitro and in vivo.
Colorectal Neoplasms
Polyamines, diamine oxidase, and ornithine decarboxylase activity in colorectal cancer and in normal surrounding mucosa.
Colorectal Neoplasms
Targeted antitumor effect induced by hTERT promoter mediated ODC antisense adenovirus.
Colorectal Neoplasms
Two chromosomal locations for human ornithine decarboxylase gene sequences and elevated expression in colorectal neoplasia.
Colorectal Neoplasms
Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine.
Colorectal Neoplasms
[A study of ornithine decarboxylase activity in tumor tissue and rectal mucosa in patients with colorectal cancer or adenoma]
Coma
Cerebral polyamine metabolism in reversible hypoglycemia of rat: relationship to energy metabolites and calcium.
Communicable Diseases
Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution.
Craniocerebral Trauma
Activation of ornithine decarboxylase and accumulation of putrescine after traumatic brain injury.
Crohn Disease
Colonic ornithine decarboxylase in inflammatory bowel disease: ileorectal activity gradient, guanosine triphosphate stimulation, and association with epithelial regeneration but not the degree of inflammation and clinical features.
Crohn Disease
Immunohistochemical expression of ornithine decarboxylase, diamine oxidase, putrescine, and spermine in normal canine enterocolic mucosa, in chronic colitis, and in colorectal cancer.
Crohn Disease
Increased colonic ornithine decarboxylase activity in inflammatory bowel disease in children.
Crohn Disease
Ornithine decarboxylase in colonic mucosa from patients with moderate or severe Crohn's disease and ulcerative colitis.
Crohn Disease
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Cystic Fibrosis
Identification of differentially expressed genes in normal and tumor human gastric tissue.
Cystic Fibrosis
Ornithine decarboxylase and S-adenosyl methionine decarboxylase in skin fibroblasts of normal and cystic fibrosis patients.
Cysts
Failure of treatment with alpha-difluoromethylornithine against secondary multilocular echinococcosis in mice.
Dehydration
Effect of dehydration and arginine vasopressin on renal ornithine decarboxylase activity in mice.
Dehydration
Expression of arginine decarboxylase and ornithine decarboxylase genes in apple cells and stressed shoots.
Demyelinating Diseases
A Minimally-invasive Blood-derived Biomarker of Oligodendrocyte Cell-loss in Multiple Sclerosis.
Demyelinating Diseases
Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination.
Dermatitis
Enhancing effect of ultraviolet A on ornithine decarboxylase induction and dermatitis evoked by 12-o-tetradecanoylphorbol-13-acetate and its inhibition by curcumin in mouse skin.
Dermatitis, Contact
Elevated Epidermal Ornithine Decarboxylase Activity Suppresses Contact Hypersensitivity.
Dermatitis, Contact
Protective effect of isoflavone derivative against photocarcinogenesis in a mouse model.
Dermatitis, Phototoxic
Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity.
Dermoid Cyst
Ovarian dermoid cyst-associated autoimmune hemolytic anemia: a case report with emphasis on pathogenic mechanisms.
Dermoid Cyst
Safety and Efficacy of Laparoscopic Oophorocystectomy for Ovarian Dermoid Cyst Associated With Autoimmune Hemolytic Anemia.
Diabetes Mellitus
Dietary lipid modulation of Na+/glucose co-transporter (SGLT1), Na+/K+ ATPase, and ornithine decarboxylase gene expression in the rat small intestine in diabetes mellitus.
Diabetes Mellitus
Influences of age and sexual maturity on the response of renal ornithine decarboxylase activity to diabetes mellitus.
Diabetes Mellitus, Experimental
Increased expression of ornithine decarboxylase in distal tubules of early diabetic rat kidneys: are polyamines paracrine hypertrophic factors?
Diabetes Mellitus, Experimental
Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes.
Diabetes Mellitus, Type 1
Protective effects of polyamine depletion in mouse models of type 1 diabetes: implications for therapy.
Diabetes Mellitus, Type 1
The effects of 2,3-diphosphoglycerate, adenosine triphosphate, and glycosylated hemoglobin on the hemoglobin-oxygen affinity of diabetic patients.
Diabetes Mellitus, Type 2
The effects of 2,3-diphosphoglycerate, adenosine triphosphate, and glycosylated hemoglobin on the hemoglobin-oxygen affinity of diabetic patients.
Duodenal Ulcer
[Effect of the hexapeptide dalargin on ornithine decarboxylase activity in the duodenal mucosa of rats in experimental duodenal ulcer]
Duodenal Ulcer
[Effect of the peripheral administration of dalargin on ornithine decarboxylase activity in the duodenal mucosa of rats with experimental duodenal ulcers]
Encephalomyelitis
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.
Encephalomyelitis, Autoimmune, Experimental
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.
Endometrial Neoplasms
Ornithine decarboxylase activity in human endometrium and endometrial cancer cells.
Endometrial Neoplasms
Ornithine decarboxylase as a therapeutic target for endometrial cancer.
Endotoxemia
Inhibition of ornithine decarboxylase restores hypoxic pulmonary vasoconstriction in endotoxemic mice.
Epidermal Cyst
Effects of 50 Hz magnetic fields on UV-induced skin tumourigenesis in ODC-transgenic and non-transgenic mice.
Epilepsy
Nuclear magnetic resonance spectroscopy study on energy metabolism, intracellular pH, and free Mg2+ concentration in the brain of transgenic mice overexpressing human ornithine decarboxylase gene.
Epiretinal Membrane
Ornithine decarboxylase activity during formation of experimental epiretinal membranes.
Erythema
Effects of butylated hydroxytoluene upon PUVA-tumorigenesis and induction of ornithine decarboxylase activity in the mouse.
Erythema
Evaluation of a topical iron chelator in animals and in human beings: short-term photoprotection by 2-furildioxime.
Erythema
Photoprotection by honeybush extracts, hesperidin and mangiferin against UVB-induced skin damage in SKH-1 mice.
Erythema
Protective role of butylated hydroxytoluene and certain carotenoids in photocarcinogenesis.
Erythema
Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity.
Erythema
The induction of erythema, edema, and the polyamine synthesis enzymes ornithine decarboxylase and S-adenosyl-L-methionine decarboxylase in hairless mouse skin by psoralens and longwave ultraviolet light.
Erythema
The inflammatory and proliferative response of normal skin in a model for acute chemical injury: ornithine decarboxylase induction as a common feature in various models for acute skin injury.
Esophageal Neoplasms
Elevated expression of the ornithine decarboxylase gene in human esophageal cancer.
Esophageal Neoplasms
Increased expression of ornithine decarboxylase messenger RNA in human esophageal carcinoma.
Esophageal Neoplasms
Phase I/II trial of preoperative oxaliplatin, docetaxel, and capecitabine with concurrent radiation therapy in localized carcinoma of the esophagus or gastroesophageal junction.
Esophageal Neoplasms
Tryosine kinase and ornithine decarboxylase activation in children with Helicobactor pylori gastritis.
Esophageal Neoplasms
[Ornithine decarboxylase and S-adenosylmethionine decarboxylase bi-antisense virus inhibit growth and invasion of esophageal cancer cell line Eca109]
Esophageal Squamous Cell Carcinoma
Antizyme inhibitor 1: a potential carcinogenic molecule.
Esophageal Squamous Cell Carcinoma
Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression.
Esophagitis
Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression.
Esophagitis, Peptic
Ornithine decarboxylase (ODC) levels in children with reflux esophagitis.
Fatty Liver
Effects of a high-fiber diet on hepatocyte apoptosis and liver regeneration after partial hepatectomy in rats with fatty liver.
Fetal Growth Retardation
Inhibition of placental ornithine decarboxylase by DL-alpha-difluoro-methyl ornithine causes fetal growth restriction in rat.
Fetal Growth Retardation
Ornithine decarboxylase inhibitors and fetal growth retardation in mice.
Fetal Growth Retardation
[Changes in enzyme activity associated with polyamine metabolism in the liver of experimental IUGR rats]
Fibrosarcoma
Effect of difluoromethylornithine on host and tumor polyamine metabolism during total parenteral nutrition.
Fibrosarcoma
Endogenous tumor growth factor indicated by increased ornithine decarboxylase activity in malignant cells treated with host serum ascites fluid.
Fibrosarcoma
Transforming growth factor beta 1 selectively regulates ornithine decarboxylase gene expression in malignant H-ras transformed fibrosarcoma cell lines.
Fibrosarcoma
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines.
Gallbladder Neoplasms
Gallbladder mucosa ornithine decarboxylase activity is increased in patients with anomalous arrangement of the pancreaticobiliary duct.
Gallstones
Routine surveillance cholangiography after percutaneous cholecystostomy delays drain removal and cholecystectomy.
Gastric Fistula
Lingual factors enhance the increase of ornithine decarboxylase activity in rat jejunal mucosa after feeding.
Gastritis
Difluoromethylornithine Is a Novel Inhibitor of Helicobacter pylori Growth, CagA Translocation, and Interleukin-8 Induction.
Gastritis
Effect of prolonged beta-carotene or DL-alpha-tocopheryl acetate supplementation on ornithine decarboxylase activity in human atrophic stomach mucosa.
Gastritis
Expression of ornithine decarboxylase in precancerous and cancerous gastric lesions.
Gastritis
Ornithine decarboxylase activity is a marker of premalignancy in longstanding Helicobacter pylori infection.
Gastritis
Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production.
Gastritis
Tryosine kinase and ornithine decarboxylase activation in children with Helicobactor pylori gastritis.
Gastritis, Atrophic
Effect of beta-carotene supplementation on the activity of ornithine decarboxylase (ODC) in stomach mucosa of patients with chronic atrophic gastritis.
Gastritis, Atrophic
Expression of ornithine decarboxylase in precancerous and cancerous gastric lesions.
Gastritis, Atrophic
Gene expression of ornithine decarboxylase, cyclooxygenase-2, and gastrin in atrophic gastric mucosa infected with Helicobacter pylori before and after eradication therapy.
Gastritis, Atrophic
Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population.
Gastritis, Atrophic
Increase in apoptosis and decrease in ornithine decarboxylase activity of the gastric mucosa in patients with atrophic gastritis and gastric ulcer after successful eradication of Helicobacter pylori.
Gastritis, Atrophic
Severe atrophic gastritis with extreme hypergastrinemia and gene expression of ornithine decarboxylase (ODC) and cyclo-oxygenase-2 (COX-2) expression: comparison with gastric cancer.
Gastritis, Atrophic
[The effect of beta-carotene on the dynamics of ornithine decarboxylase activity in atrophic mucous membranes and in stomach polyp tissue]
Gastroenteritis
[Value of the detection of ornithine decarboxylase in Escherichia coli from infantile gastroenteritis]
Gastrointestinal Neoplasms
Increase in apoptosis and decrease in ornithine decarboxylase activity of the gastric mucosa in patients with atrophic gastritis and gastric ulcer after successful eradication of Helicobacter pylori.
Gastrointestinal Neoplasms
Polyamine biosynthesis in relation to K-ras and p-53 mutations in colorectal carcinoma.
Gastrointestinal Neoplasms
Single-injection ornithine decarboxylase-directed antisense therapy using atelocollagen to suppress human cancer growth.
Genetic Diseases, Inborn
Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation.
Giardiasis
Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution.
Glioblastoma
Degrees of malignancy in human primary central nervous system tumors: ornithine decarboxylase levels as better indicators than adenosylmethionine decarboxylase levels.
Glioblastoma
Inhibition of the growth of U-251 human glioblastoma in nude mice by polyamine deprivation.
Glioblastoma
Phase II trial of recombinant interferon-alpha-2a and eflornithine in patients with recurrent glioma.
Glioblastoma
Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme.
Glioblastoma
Relationship between ornithine decarboxylase levels in anaplastic gliomas and progression-free survival in patients treated with DFMO-PCV chemotherapy.
Glioblastoma
Role of ornithine decarboxylase in the regulation of cell growth by IL-1 and tumor necrosis factor.
Glioma
Activity of ornithine decarboxylase (ODC) and polyamine levels as biochemical markers of malignancy in human brain tumors.
Glioma
Antitumor effects of vitamin A and inhibitors of ornithine decarboxylase in cultured neuroblastoma and glioma cells.
Glioma
Butyrate-induced increase in neuron-specific enolase and ornithine decarboxylase in anaplastic glioma cells.
Glioma
Calcium dependence for increased antizyme inhibitory activity of ornithine decarboxylase in rat glioma cells.
Glioma
Characterization of arginine decarboxylase in rat brain and liver: distinction from ornithine decarboxylase.
Glioma
Cyclic AMP-mediated induction of ornithine decarboxylase of glioma and neuroblastoma cells.
Glioma
Dissociation of RNA synthesis from the calcium requirement for serum-increased ornithine decarboxylase activity in rat glioma cells.
Glioma
Effect of GABA and isogabaculine on ornithine decarboxylase and putrescine metabolism.
Glioma
Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase.
Glioma
Metabolism of polyamines by cultured glioma cells. Effect of asparagine on gamma-aminobutyric acid concentrations.
Glioma
Morphine inhibits cyclic AMP-dependent protein kinase and ornithine decarboxylase activities in neuroblastoma X glioma hybrid cells.
Glioma
New transition state-based inhibitor for human ornithine decarboxylase inhibits growth of tumor cells.
Glioma
Opiates and cultured neuroblastoma x glioma cells. Effect on cyclic AMP and polyamine levels and on ornithine decarboxylase and protein kinase activities.
Glioma
Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme.
Glioma
Phase III randomized study of postradiotherapy chemotherapy with combination alpha-difluoromethylornithine-PCV versus PCV for anaplastic gliomas.
Glioma
Polyamines and protein kinase I. Induction of ornithine decarboxylase and activation of protein kinase in rat glioma cells.
Glioma
Potassium channel blockers quinidine and caesium halt cell proliferation in C6 glioma cells via a polyamine-dependent mechanism.
Glioma
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Glioma
Protein kinase C-mediated in vitro invasion of human glioma cells through extracellular-signal-regulated kinase and ornithine decarboxylase.
Glioma
Regional distribution of ornithine decarboxylase activity and polyamine levels in experimental cat brain tumors.
Glioma
Relationship between ornithine decarboxylase levels in anaplastic gliomas and progression-free survival in patients treated with DFMO-PCV chemotherapy.
Glioma
Structural requirements for novel coenzyme-substrate derivatives to inhibit intracellular ornithine decarboxylase and cell proliferation.
Glioma
Tissue-based assay for ornithine decarboxylase to identify patients likely to respond to difluoromethylornithine.
Gliosarcoma
Decreased cytotoxicity of cis-diamminedichloroplatinum(II) by alpha-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro.
Gliosarcoma
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Gliosarcoma
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Glomerulonephritis
Agmatine inhibits cell proliferation and improves renal function in anti-thy-1 glomerulonephritis.
Granuloma
The regulation of lymphoid function during schistosomiasis: influence of T-cell-derived suppressor molecules on antigen recognition, cellular activation and granuloma formation.
Head and Neck Neoplasms
Cell cycle distribution and ornithine decarboxylase activity in head and neck cancer in response to enteral nutrition.
Head and Neck Neoplasms
Ornithine decarboxylase activity in tumor and normal tissue of head and neck cancer patients.
Hearing Loss
Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.
Hemangioblastoma
Degrees of malignancy in human primary central nervous system tumors: ornithine decarboxylase levels as better indicators than adenosylmethionine decarboxylase levels.
Hepatitis
Changes in polyamine metabolism of rat liver after administration of D-galactosamine. Favorable effects of putrescine administration on galactosamine-induced hepatic injury.
Hepatitis
Ornithine decarboxylase activity in the non-cancerous hepatic tissue of patients with hepatocellular carcinoma.
Hepatitis C
Ornithine decarboxylase activity in the non-cancerous hepatic tissue of patients with hepatocellular carcinoma.
Hepatitis C
The Impact of Pegylated-Interferon ?-2b on Partial and Massive Hepatectomy Model in Rats.
Hepatomegaly
Induction of hepatic ornithine decarboxylase by hypolipidemic drugs with hepatic peroxisome proliferative activity.
Herpes Simplex
A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients.
Herpes Simplex
Isolation and characterization of the growth-stimulating factor in supernatants of herpes simplex virus type 2 infected cells.
Herpes Zoster
Sexual dimorphism of ornithine decarboxylase in the mouse adrenal: influence of polyamine deprivation on catecholamine and corticoid levels.
Hirsutism
Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma.
Hydrocephalus
Ornithine decarboxylase in developing brain of normal and hydrocephalic rats. Biochemical and immunohistochemical studies.
Hyperalgesia
?-Difluoromethylornithine suppresses inflammatory arthritis by impairing myeloid-derived suppressor cells.
Hypercalcemia
A protective role of 1,25-dihydroxyvitamin D3 in chemically induced rat colon carcinogenesis.
Hyperglycemia
Alternative antiglycation mechanisms: are spermine and fructosamine-3-kinase part of a carbonyl damage control pathway?
Hyperglycemia
Effect of streptozotocin-induced diabetes on renal ornithine decarboxylase activity.
Hyperglycemia
Exogenous spermine attenuates myocardial fibrosis in diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress and the canonical Wnt signaling pathway.
Hyperprolactinemia
Does hyperprolactinemia affect hepatic regeneration independent of sex steroids?
Hyperprolactinemia
Effects of hyperprolactinemia on ornithine decarboxylase activity and polyamine levels in seminal vesicles of genetically prolactin-deficient adult dwarf mice.
Hypersensitivity
Postnatal developmental changes in inner ear ornithine decarboxylase (ODC).
Hypertension
Blunted cardiovascular growth induction during prolonged nitric oxide synthase blockade.
Hypertension
Decreased ornithine decarboxylase activity in the kidneys of Dahl salt-sensitive rats.
Hypertension
Eflornithine treatment in SHR: potential role of vascular polyamines and ornithine decarboxylase in hypertension.
Hypertension
Polyamines, vascular smooth muscle, and deoxycorticosterone acetate-salt hypertension.
Hypertension, Pulmonary
alpha-Difluoromethylornithine attenuates monocrotaline-induced airway/lung dysfunction.
Hypertension, Pulmonary
alpha-Difluoromethylornithine, an inhibitor of polyamine synthesis, attenuates monocrotaline-induced pulmonary vascular hyperresponsiveness in isolated perfused rat lungs.
Hypertension, Pulmonary
Prolonged activation of rat lung ornithine decarboxylase in monocrotaline-induced pulmonary hypertension.
Hypertension, Pulmonary
Suppression of polyamine biosynthesis prevents monocrotaline-induced pulmonary edema and arterial medial thickening.
Hypertension, Renovascular
[Polyamines and cardiovascular hypertrophy in experimental hypertension]
Hyperthyroidism
Catecholamine-thyroid hormone interaction on myocardial ornithine decarboxylase.
Hyperthyroidism
Neonatal hyperthyroidism causes premature development of baroreceptor-mediated cardiac sympathetic reflexes.
Hyperthyroidism
Regulation of ornithine decarboxylase activity in the developing heart of euthyroid or hyperthyroid rats.
Hyperthyroidism
Role of thyroid hormone in the development of beta adrenergic control of ornithine decarboxylase in rat heart and kidney.
Hyperthyroidism
The effect of catabolic states induced by hyperthyroidism, hypercorticolism, and fasting on muscle ornithine decarboxylase activity.
Hyperthyroidism
Thyroid hormone differentially regulates development of beta-adrenergic receptors, adenylate cyclase and ornithine decarboxylase in rat heart and kidney.
Hyperthyroidism
Thyroid hormones modulate ornithine decarboxylase in the immature rat cerebellum.
Hyperthyroidism
Thyroxine effects on polyamine metabolism in rat cerebellum and brain cortex during postnatal development.
Hypertrophy, Left Ventricular
Overexpression of ornithine decarboxylase decreases ventricular systolic function during induction of cardiac hypertrophy.
Hypertrophy, Right Ventricular
Dietary restriction, polyamines and monocrotaline-induced pulmonary hypertension.
Hypertrophy, Right Ventricular
Prolonged activation of rat lung ornithine decarboxylase in monocrotaline-induced pulmonary hypertension.
Hypertrophy, Right Ventricular
Suppression of polyamine biosynthesis prevents monocrotaline-induced pulmonary edema and arterial medial thickening.
Hyperventilation
Effects of an allosteric hemoglobin affinity modulator on arterial blood gases and cardiopulmonary responses during normoxic and hypoxic low-intensity exercise.
Hypoglycemia
Cerebral polyamine metabolism in reversible hypoglycemia of rat: relationship to energy metabolites and calcium.
Hypoglycemia
Ontogeny of functional sympathetic innervation to the heart and adrenal medulla in the preweanling rat.
Hypoglycemia
Prenatal ethanol alters development of cardiac ornithine decarboxylase response to adrenergic agents in rat. I. Continuous exposure.
Hypoglycemia
Prenatal ethanol exposure alters development of heart ornithine decarboxylase response to insulin in rat. II. Daily dose.
Hypoglycemia
Stimulation of ornithine decarboxylase activity by insulin in developing rat brain.
Hypoglycemia
Sympathetic responses of the heart and adrenal medulla in developing Dahl hypertensive rats.
Hypotension
Neonatal hyperthyroidism causes premature development of baroreceptor-mediated cardiac sympathetic reflexes.
Hypotension
Neonatal nutritional deprivation or enhancement: the cardiac-sympathetic axis and its role in cardiac growth and stress responses.
Hypothyroidism
Ornithine decarboxylase and polyamines in developing rat brain and heart: Effects of perinatal hypothyroidism.
Hypothyroidism
Role of thyroid hormone in the development of beta adrenergic control of ornithine decarboxylase in rat heart and kidney.
Hypoxia, Brain
Acute hypoxia increases ornithine decarboxylase activity and polyamine concentrations in fetal rat brain.
Hypoxia, Brain
In vivo effect of RU 24722 and drugs used for the treatment on senile cerebral insufficiency on rat brain ornithine decarboxylase.
Infarction, Middle Cerebral Artery
Enhanced ornithine decarboxylase activity is associated with attenuated rate of damage evolution and reduction of infarct volume in transient middle cerebral artery occlusion in the rat.
Infarction, Middle Cerebral Artery
Ornithine decarboxylase knockdown exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain.
Infarction, Middle Cerebral Artery
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Infections
A Trypanosoma brucei bloodstream form mutant deficient in ornithine decarboxylase can protect against wild-type infection in mice.
Infections
Antitrypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-L-methionine.
Infections
Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes.
Infections
Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni.
Infections
Biphasic stimulation of polyamine biosynthesis in primary mouse kidney cells by infection with polyoma virus:uncoupling from DNA and rRNA synthesis.
Infections
Chlamydia trachomatis inhibits inducible NO synthase in human mesenchymal stem cells by stimulating polyamine synthesis.
Infections
Correlation between Ornithine Decarboxylase and Putrescine in Tomato Plants Infected by Citrus Exocortis Viroid or Treated with Ethephon.
Infections
Cure of murine Trypanosoma brucei rhodesiense infections with an S-adenosylmethionine decarboxylase inhibitor.
Infections
Cytokine and nitric oxide production by Trypanosoma brucei infection in rats fed polyamine-deficient chow.
Infections
Dissociation of ras oncogene-induced gene expression and anchorage-independent growth in a series of somatic cell mutants.
Infections
DL-alpha-difluoromethylarginine inhibits intracellular Trypanosoma cruzi multiplication by affecting cell division but not trypomastigote-amastigote transformation.
Infections
Effects of the ornithine decarboxylase inhibitors DL-alpha-difluoromethylornithine and alpha-monofluoromethyldehydroornithine methyl ester alone and in combination with suramin against Trypanosoma brucei brucei central nervous system models.
Infections
Endogenous polyamine levels in macrophages is sufficient to support growth of Toxoplasma gondii.
Infections
Experimental fecal transmission of human cryptosporidia to pigs, and attempted treatment with an ornithine decarboxylase inhibitor.
Infections
Expression of c-Myc is related to host cell death following Salmonella typhimurium infection in macrophage.
Infections
First report of the inhibition of arbuscular mycorrhizal infection of Pisum sativum by specific and irreversible inhibition of polyamine biosynthesis or by gibberellic acid treatment.
Infections
Helicobacter pylori CagA induces ornithine decarboxylase upregulation via Src/MEK/ERK/c-Myc pathway: implication for progression of gastric diseases.
Infections
In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors.
Infections
Inhibition of cytomegalovirus-stimulated human cell ornithine decarboxylase by alpha-difluoromethylornithine.
Infections
Isolation and characterization of the growth-stimulating factor in supernatants of herpes simplex virus type 2 infected cells.
Infections
Kinetic studies on the control of the bean rust fungus (Uromyces phaseoli L.) by an inhibitor of polyamine biosynthesis.
Infections
Leishmania tropica major: effect of paromomycin and pentamidine on polyamine levels in the skin of normal and infected mice.
Infections
Lytic infection of pseudorabies virus in the presence of spermine, spermidine, or DFMO.
Infections
Mucosal ornithine decarboxylase, polyamines, and hyperplasia in infected intestine.
Infections
Oral putrescine restores virulence of ornithine decarboxylase-deficient Leishmania donovani in mice.
Infections
Ornithine decarboxylase activity is a marker of premalignancy in longstanding Helicobacter pylori infection.
Infections
Ornithine decarboxylase expression leads to translocation and activation of protein kinase CK2 in vivo.
Infections
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Infections
Ornithine decarboxylase knockout in Tapesia yallundae abolishes infection plaque formation in vitro but does not reduce virulence toward wheat.
Infections
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications.
Infections
Polyamine metabolism in flax in response to treatment with pathogenic and non-pathogenic Fusarium strains.
Infections
Remarkable activation of polyamine biosynthesis in hematopoiesis and hyperplasia of spleen in mice with hemolytic anemia caused by infection with Plasmodium berghei.
Infections
Successful treatment of lethal protozoal infections with the ornithine decarboxylase inhibitor, alpha-difluoromethylornithine.
Infections
Synergism between 9-deazainosine and DL-alpha-difluoromethylornithine in treatment of experimental African trypanosomiasis.
Infections
Synthesis of Semliki-forest virus in polyamine-depleted baby-hamster kidney cells.
Infections
Temporal studies of factors associated with changes in transcription during Q fever.
Infections
Tryosine kinase and ornithine decarboxylase activation in children with Helicobactor pylori gastritis.
Infections
[Treatment of human trypanosomiasis caused by Trypanosoma brucei gambiense using alpha-difluoromethylornithine. Results in 7 patients]
Infertility
Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility.
Infertility, Female
Transcriptome response and developmental implications of RNAi-mediated ODC knockdown in tobacco.
Inflammatory Bowel Diseases
Colonic ornithine decarboxylase in inflammatory bowel disease: ileorectal activity gradient, guanosine triphosphate stimulation, and association with epithelial regeneration but not the degree of inflammation and clinical features.
Inflammatory Bowel Diseases
Increased colonic ornithine decarboxylase activity in inflammatory bowel disease in children.
Influenza, Human
Impaired measles virus-specific cytotoxic T cell responses in multiple sclerosis.
Insulin Resistance
Ethanol-induced insulin resistance suppresses the expression of embryonic ornithine decarboxylase activity.
Insulinoma
Interleukin-1beta induces ornithine decarboxylase activity in insulin-producing cells.
Intellectual Disability
Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development.
Intestinal Polyposis
Efficacy and safety of eflornithine (CPP-1X)/sulindac combination therapy versus each as monotherapy in patients with familial adenomatous polyposis (FAP): design and rationale of a randomized, double-blind, Phase III trial.
Intracranial Hypertension
Osteoplastic decompressive craniotomy-an alternative to decompressive craniectomy.
Iron Overload
Effect of iron overload on the benzoyl peroxide-mediated tumor promotion in mouse skin.
Iron Overload
Evidence that iron-overload promotes 7,12-dimethylbenz(a)anthracene- induced skin tumorigenesis in mice.
Ischemic Attack, Transient
Activity of ornithine decarboxylase and S-adenosylmethionine decarboxylase in transient cerebral ischemia: relationship to the duration of vascular occlusion.
Ischemic Attack, Transient
Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage.
Ischemic Attack, Transient
Modulation of ornithine decarboxylase mRNA following transient ischemia in the gerbil brain.
Ischemic Attack, Transient
Ornithine decarboxylase activity and immunohistochemical location in postischemic brain.
Ischemic Attack, Transient
Ornithine decarboxylase activity in cerebral post-ischemic reperfusion damage: effect of methionine sulfoximine.
Ischemic Attack, Transient
Ornithine decarboxylase knockdown exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain.
Ischemic Attack, Transient
[Expression of ornithine decarboxylase mRNA in the cortex and hippocampus of rat after transient cerebral ischemia]
Ischemic Stroke
Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: a study using ornithine decarboxylase-overexpressing transgenic rats.
Ketosis
Effect of streptozotocin-induced diabetes on renal ornithine decarboxylase activity.
Ketosis
Reestimation of the effects of inorganic phosphates on the equilibrium between oxygen and hemoglobin.
Kidney Neoplasms
Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies.
Leg Ulcer
Combined antibacterial effects of tissue-tolerable plasma and a modern conventional liquid antiseptic on chronic wound treatment.
Leishmaniasis
Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host.
Leishmaniasis
Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review.
Leishmaniasis, Cutaneous
Arginase I, polyamine, and prostaglandin E2 pathways suppress the inflammatory response and contribute to diffuse cutaneous leishmaniasis.
Leishmaniasis, Visceral
An immunoprophylactic evaluation of Ld-ODC derived HLA-A0201 restricted peptides against visceral leishmaniasis.
Leishmaniasis, Visceral
Evaluating the immunomodulatory responses of LdODC-derived MHC Class-II restricted peptides against VL.
Leishmaniasis, Visceral
Immunomodulation induced through ornithine decarboxylase DNA immunization in Balb/c mice infected with Leishmania donovani.
Leishmaniasis, Visceral
Leishmania donovani: impairment of the cellular immune response against recombinant ornithine decarboxylase protein as a possible evasion strategy of Leishmania in visceral leishmaniasis.
Leishmaniasis, Visceral
Molecular modeling and virtual screening approach to discover potential antileishmanial inhibitors against ornithine decarboxylase.
Leishmaniasis, Visceral
Novel convenient synthesis of biologically active esters of hydroxylamine.
Leishmaniasis, Visceral
Oral putrescine restores virulence of ornithine decarboxylase-deficient Leishmania donovani in mice.
Leukemia
15-Deoxyspergualin, an antiproliferative agent for human and mouse leukemia cells shows inhibitory effects on the synthetic pathway of polyamines.
Leukemia
Alpha-difluoromethylornithine, ornithine decarboxylase inhibitor, antagonizes H2O2-induced cytotoxicity in HL-60 leukemia cells: regulation of iron-dependent lysosomal damage.
Leukemia
Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents.
Leukemia
Combined use of alpha-difluoromethylornithine and an inhibitor of S-adenosylmethionine decarboxylase in mice bearing P388 leukemia or Lewis lung carcinoma.
Leukemia
Curcumin induces apoptosis through an ornithine decarboxylase-dependent pathway in human promyelocytic leukemia HL-60 cells.
Leukemia
Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies.
Leukemia
Diethylglyoxal bis(guanylhydrazone): a novel highly potent inhibitor of S-adenosylmethionine decarboxylase with promising properties for potential chemotherapeutic use.
Leukemia
Early changes in ornithine decarboxylase activity and polyamines during erythroid differentiation of Friend leukemia cells.
Leukemia
Early changes in ornithine decarboxylase activity during Friend leukemia cell differentiation.
Leukemia
Effect of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on L1210 leukemia in mice.
Leukemia
Effect of calvatic acid and its analogs on ornithine decarboxylase activity in tumour cells.
Leukemia
Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells.
Leukemia
Effects of alpha-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) on the growth of experimental renal adenocarcinoma in mice.
Leukemia
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
Leukemia
Evaluation of selected lichens from iceland for cancer chemopreventive and cytotoxic activity.
Leukemia
Hydroxydibenzoylmethane induces apoptosis through repressing ornithine decarboxylase in human promyelocytic leukemia HL-60 cells.
Leukemia
Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia.
Leukemia
Inhibition of the expression of ornithine decarboxylase by haloperidol in difluoromethylornithine-resistant leukemia cells.
Leukemia
Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines.
Leukemia
Modulation of ornithine decarboxylase gene transcript levels by differentiation inducers in human promyelocytic leukemia HL60 cells.
Leukemia
Ornithine decarboxylase and spermidine/spermine N1-acetyltransferase are induced in K562 cells by S-adenosylmethionine decarboxylase inhibitor methylglyoxal bis(guanylhydrazone) but not by analogous methylglyoxal bis(butylamidinohydrazone).
Leukemia
Ornithine decarboxylase induction and nucleolar RNA synthesis in Friend leukemia cells.
Leukemia
Ornithine decarboxylase interferes with macrophage-like differentiation and matrix metalloproteinase-9 expression by tumor necrosis factor alpha via NF-kappaB.
Leukemia
Ornithine decarboxylase: essential in proliferation but not differentiation of human promyelocytic leukemia cells.
Leukemia
Overproduction of ornithine decarboxylase confers an apparent growth advantage to mouse tumor cells.
Leukemia
Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis.
Leukemia
Phosphatidylinositol 3-kinase is required for the induction of ornithine decarboxylase in leukemia cells stimulated to growth.
Leukemia
Regulation of ornithine decarboxylase expression by anisosmotic shock in alpha-difluoromethylornithine-resistant L1210 cells.
Leukemia
Similar, potent tumor-promoting activity of all isomers of teleocidins A and B in a two-stage carcinogenesis experiment on the skin of CD-1 mice.
Leukemia
Spermine oxidation leads to necrosis with plasma membrane phosphatidylserine redistribution in mouse leukemia cells.
Leukemia
Synergistic antileukemic effect of two polyamine synthesis inhibitors. Host survival and cell-cycle kinetic analysis.
Leukemia
Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids.
Leukemia
Synthetic analogues (indolactams) of (-)-indolactam-V are new congeners of the teleocidin class of tumor promoters.
Leukemia
Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanoylphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis.
Leukemia
The effects of single administration of an antitumor platinum compound on ornithine decarboxylase activity in certain tissues of mice bearing L1210 leukemia.
Leukemia
The long leader sequence of the mouse ornithine decarboxylase mRNA, previously suspected to be a cloning artifact, is probably a product of recombination with MuLV-like retrovirus.
Leukemia
The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects.
Leukemia
Thymoquinone and Difluoromethylornithine (DFMO) Synergistically Induce Apoptosis of Human Acute T Lymphoblastic Leukemia Jurkat Cells Through the Modulation of Epigenetic Pathways.
Leukemia L1210
Overproduction of ornithine decarboxylase confers an apparent growth advantage to mouse tumor cells.
Leukemia P388
In the search for new anticancer drugs. 13. Phosphonic and phosphinic analogues of ornithine.
Leukemia, Erythroblastic, Acute
Altered expression of beta-globin, transferrin receptor, and ornithine decarboxylase in Friend murine erythroleukemia cells inhibited by alpha-difluoromethylornithine.
Leukemia, Erythroblastic, Acute
D,L-alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, induces differentiation in MEL cells.
Leukemia, Erythroblastic, Acute
Effect of ATP depletion and phenanthroline on the spermidine-mediated decay of ornithine decarboxylase in erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Effect of sodium arsenite on the induction and turnover of ornithine decarboxylase activity in erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Effects of ornithine decarboxylase inhibition on c-myc expression during murine erythroleukemia cell proliferation and differentiation.
Leukemia, Erythroblastic, Acute
Effects of retinoic acid versus dimethyl sulfoxide on Friend erythroleukemia cell growth. I. Cell proliferation, RNA content, and protein content.
Leukemia, Erythroblastic, Acute
Phosphorylation of ornithine decarboxylase in intact erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Relationship between ornithine decarboxylase activity and hexamethylene bisacetamide-induced differentiation of murine erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Stabilization of ornithine decarboxylase in erythroleukemia cells depleted of ATP.
Leukemia, Lymphocytic, Chronic, B-Cell
Alterations in ornithine decarboxylase and transglutaminase activities in lymphocytes from untreated patients with chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia.
Leukemia, Lymphoid
Comparison of the biological effects of four irreversible inhibitors of ornithine decarboxylase in two murine lymphocytic leukemia cell lines.
Leukemia, Lymphoid
In the search for new anticancer drugs. 13. Phosphonic and phosphinic analogues of ornithine.
Leukemia, Lymphoid
Inhibition by polyamines of methylthiopropylamine-induced ornithine decarboxylase in human lymphoid leukemia Molt 4B cells.
Leukemia, Lymphoid
Polyamine deprivation-induced enhanced uptake of methylglyoxal bis(guanylhydrazone) by tumor cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Peripheral blood leucocytes ornithine decarboxylase activity in chronic myeloid leukemia patients: prognostic and therapeutic implications.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Certain biochemical features of leukocytes in blast crisis of chronic myelogenous leukemia]
Leukemia, Myeloid
Development of resistance to hydroxyurea during treatment of human myelogenous leukemia K562 cells with alpha-difluoromethylornithine as a result of coamplification of genes for ornithine decarboxylase and ribonucleotide reductase R2 subunit.
Liver Cirrhosis
Effect of inorganic ions on the oxyhemoglobin dissociation curve of severely ill patients.
Liver Diseases
Peculiarity of prooxidant-antioxidant balance indicators in patients with nonalcoholic fatty liver disease who have been exposed to ionizing radiation due to the Chornobyl NPP accident.
Liver Failure
Effect of hepatic failure toxins on liver thymidine kinase activity and ornithine decarboxylase activity after massive necrosis with acetaminophen in the rat.
Liver Neoplasms
Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer.
Liver Neoplasms, Experimental
Comparison of ornithine decarboxylase from rat liver, rat hepatoma and mouse kidney.
Liver Neoplasms, Experimental
Fasting does not abolish the diurnal oscillation of ornithine decarboxylase activity in Morris hepatoma 5123-C.
Liver Neoplasms, Experimental
Ornithine decarboxylase lability in 2 transplantable highly deviated rat hepatomas.
Liver Neoplasms, Experimental
Studies on ornithine decarboxylase from liver, kidney and tumoral tissues during activity decay following cycloheximide administration.
Lung Injury
Repair of oxygen-induced lung injury in adult rats. The role of ornithine decarboxylase and polyamines.
Lung Neoplasms
Adenovirus-mediated expression of both antisense ornithine decarboxylase and S-adenosylmethionine decarboxylase inhibits lung cancer cell growth.
Lung Neoplasms
Antitumor effect of antisense ornithine decarboxylase adenovirus on human lung cancer cells.
Lung Neoplasms
FATS regulates polyamine biosynthesis by promoting ODC degradation in an ER?-dependent manner in non-small-cell lung cancer.
Lung Neoplasms
Gene expression of ornithine decarboxylase in lung cancers and its clinical significance.
Lung Neoplasms
In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells.
Lung Neoplasms
New transition state-based inhibitor for human ornithine decarboxylase inhibits growth of tumor cells.
Lung Neoplasms
Ornithine decarboxylase activity as a biochemical marker in individuals predisposed to lung cancer.
Lung Neoplasms
Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer.
Lung Neoplasms
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
Lung Neoplasms
Stable siRNA-mediated silencing of antizyme inhibitor: regulation of ornithine decarboxylase activity.
Lung Neoplasms
The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells--In vitro.
Lung Neoplasms
[Inhibitory effects of ODC and AdoMetDC biantisense virus on the growth and invasion of lung cancer cell A-549]
Lupus Erythematosus, Systemic
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.
Lupus Nephritis
Regulation of ornithine decarboxylase in the kidney of autoimmune mice with the lpr gene.
Lupus Nephritis
Studies on the effects of an ornithine decarboxylase inhibitor on lupus nephritis reveal a post-transcriptional modification of the enzyme.
Lupus Nephritis
Successful treatment of lupus nephritis in MRL-lpr/lpr mice by inhibiting ornithine decarboxylase.
Lymphatic Metastasis
Effect of remedies for enhancing resistance and relieving blood stasis on metastasis in postoperative gastric cancer and ornithine decarboxylase levels.
Lymphatic Metastasis
Increased expression of ornithine decarboxylase messenger RNA in human esophageal carcinoma.
Lymphatic Metastasis
Ornithine decarboxylase activity as a prognostic marker for colorectal cancer.
Lymphatic Metastasis
[A ornithine decarboxylase activity and proliferating cell nuclear antigen in gastric cancer]
Lymphoma
A mouse lymphoma cell mutant whose major protein product is ornithine decarboxylase.
Lymphoma
An inhibitor of ornithine decarboxylase in lactogen-deprived Nb2 node rat lymphoma cells.
Lymphoma
Cyclic AMP-dependent protein kinase mediates a cyclic AMP-stimulated decrease in ornithine and S-adenosylmethionine decarboxylase activities.
Lymphoma
Effect of alpha-difluoromethylornithine on L-phenylalanine mustard-induced cytotoxicity and DNA interstrand cross-linking in a human cell line in vitro.
Lymphoma
Glucocorticoid-mediated inhibition of ornithine decarboxylyase activity in S49 lymphoma cells.
Lymphoma
Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells.
Lymphoma
Independent regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in methylthioadenosine phosphorylase-deficient malignant murine lymphoblasts.
Lymphoma
Inhibition of hormone-stimulated ornithine decarboxylase activity by lithium chloride.
Lymphoma
Inhibition of ornithine decarboxylase and S-adenosylmethionine decarboxylase activities of S49 lymphoma cells by agents increasing cyclic AMP.
Lymphoma
Ornithine decarboxylase in difluoromethylornithine-resistant mouse lymphoma cells. Two-dimensional gel analysis of synthesis and turnover.
Lymphoma
Peripheral benzodiazepine binding sites in Nb 2 node lymphoma cells: effects on prolactin-stimulated proliferation and ornithine decarboxylase activity.
Lymphoma
Prolactin stimulation of ornithine decarboxylase and mitogenesis in Nb2 node lymphoma cells: the role of protein kinase C and calcium mobilization.
Lymphoma
Prolactin-dependent mitogenesis in Nb 2 node lymphoma cells: effects of immunosuppressive cyclopeptides.
Lymphoma
Regulation of phosphodiesterase and ornithine decarboxylase by cAMP is cell cycle independent.
Lymphoma
Role of ornithine decarboxylase in proliferation of prolactin-dependent lymphoma cells.
Lymphoma
Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma.
Lymphoma
Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.
Lymphoma
The effects of low-energy 60-Hz environmental electromagnetic fields upon the growth-related enzyme ornithine decarboxylase.
Lymphoma, B-Cell
Probiotic Lactobacillus rhamnosus GG enhances gastric ulcer healing in rats.
Malaria
In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase.
Malaria
Novel properties of malarial S-adenosylmethionine decarboxylase as revealed by structural modelling.
Malaria
Plasmodium berghei: inhibition of the sporogonous cycle by alpha-difluoromethylornithine.
Malaria
The ornithine decarboxylase domain of the bifunctional ornithine decarboxylase/S-adenosylmethionine decarboxylase of Plasmodium falciparum: recombinant expression and catalytic properties of two different constructs.
Malaria
The Plasmodium falciparum bifunctional ornithine decarboxylase, S-adenosyl-L-methionine decarboxylase, enables a well balanced polyamine synthesis without domain-domain interaction.
Malaria
Transcriptional responses of Plasmodium falciparum to alpha-difluoromethylornithine-induced polyamine depletion.
Malaria
Vitamin B6-dependent enzymes in the human malaria parasite Plasmodium falciparum: a druggable target?
Malnutrition
Adaptive response of ileal mucosa to malnutrition in the rat: role of polyamines.
Malnutrition
Effects of malnutrition on some aspects of RNA metabolism in the maternal liver and fetal tissues at different stages of pregnancy in the rat.
Malnutrition
Foetal and placental ornithine decarboxylase activity in the rat--effect of maternal undernutrition.
Malnutrition
Polyamines and their biosynthetic decarboxylases in various tissues of the young rat during undernutrition.
Malnutrition
Regulation of ornithine decarboxylase synthesis. Effect of a nutritional deficiency of vitamin B6.
Malnutrition
Ribonucleic acid metabolism in rat liver during long-term adaptation to malnutrition.
Malnutrition
The activity of ornithine decarboxylase in the quadriceps and gastrocnemius muscles of rats recovering from undernutrition.
Malnutrition
The food-dependent induction of hepatic ornithine decarboxylase during undernutrition and rehabilitation.
Medulloblastoma
Degree of enhancement of polyamine biosynthetic decarboxylase activities in human tumors: a useful new index of degree of malignancy.
Medulloblastoma
Degrees of malignancy in human primary central nervous system tumors: ornithine decarboxylase levels as better indicators than adenosylmethionine decarboxylase levels.
Medulloblastoma
Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth.
Megalencephaly
Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development.
Melanoma
A cluster region of AP-1 responsive elements is required for transcriptional activity of mouse ODC gene by hepatocyte growth factor.
Melanoma
A phase I and pharmacokinetic study of SAM486A, a novel polyamine biosynthesis inhibitor, administered on a daily-times-five every-three-week schedule in patients with Advanced solid malignancies.
Melanoma
Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines.
Melanoma
Difluoromethylornithine and leukocyte interferon: a phase I study in cancer patients.
Melanoma
Effects of DL-alpha-difluoromethylornithine on the growth and metastasis of B16 melanoma in vivo.
Melanoma
Effects of inhibitors of polyamine biosynthesis on the growth and melanogenesis of murine melanoma cells.
Melanoma
Effects of treatments with alpha-difluoromethylornithine and hyperthermia on the growth and polyamine metabolism of Harding-Passey murine melanoma.
Melanoma
Hepatocyte growth factor induces pro-apoptotic genes in HepG2 hepatoma but not in B16-F1 melanoma cells.
Melanoma
Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC.
Melanoma
Interleukin-1-induced growth inhibition of human melanoma cells. Interleukin-1-induced antizyme expression is responsible for ornithine decarboxylase activity down-regulation.
Melanoma
New benzoic acid derivatives with retinoid activity: lack of direct correlation between biological activity and binding to cellular retinoic acid binding protein.
Melanoma
Regulation of ornithine decarboxylase in B16 mouse melanoma cells: synergistic activation of melanogenesis by alphaMSH and ornithine decarboxylase inhibition.
Melanoma
Retinoids increase transglutaminase activity and inhibit ornithine decarboxylase activity in Chinese hamster ovary cells and in melanoma cells stimulated to differentiate.
Melanoma
Role of ornithine decarboxylase in the regulation of cell growth by IL-1 and tumor necrosis factor.
Melanoma
Spermine/spermidine is expressed by retinal glial (Müller) cells and controls distinct K+ channels of their membrane.
Melanoma
Transfection of human melanoma cells with type I interleukin-1 (IL-1) receptor cDNA rendered them IL-1-responsive and revealed the importance of ODC activity down-regulation in IL-1-induced growth inhibition.
Melanoma, Experimental
Effect of inhibition of polyamine biosynthesis by DL-alpha-difluoromethylornithine on the growth and melanogenesis of B16 melanoma in vitro and in vivo.
Melanoma, Experimental
Effects of inhibitors of polyamine biosynthesis on the growth and melanogenesis of murine melanoma cells.
Melanoma, Experimental
Effects of treatments with alpha-difluoromethylornithine and hyperthermia on the growth and polyamine metabolism of Harding-Passey murine melanoma.
Melanoma, Experimental
Potentiation by alpha-difluoromethylornithine of the activity of 3,4-dihydroxybenzylamine, a tyrosinase-dependent melanolytic agent, against B16 melanoma.
Meningioma
Activity of ornithine decarboxylase (ODC) and polyamine levels as biochemical markers of malignancy in human brain tumors.
Meningioma
Degree of enhancement of polyamine biosynthetic decarboxylase activities in human tumors: a useful new index of degree of malignancy.
Meningioma
Degrees of malignancy in human primary central nervous system tumors: ornithine decarboxylase levels as better indicators than adenosylmethionine decarboxylase levels.
Mesothelioma
Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers.
Mesothelioma
Induction of epidermal ornithine decarboxylase activity in mouse skin exposed to biogenic silica fibers.
Mouth Neoplasms
Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line.
Mouth Neoplasms
Soy protein extract (SPE) exhibits differential in vitro cell proliferation effects in oral cancer and normal cell lines.
Multiple Myeloma
Combined treatment of human multiple myeloma cells with bortezomib and doxorubicin alters the interactome of 20S proteasomes.
Multiple Myeloma
Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia.
Multiple Sclerosis
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation.
Muscular Diseases
Polyamine biosynthetic decarboxylases in muscles of rats with different experimental myopathies.
Mycoses
Targeting polyamines of Aspergillus nidulans by siRNA specific to fungal ornithine decarboxylase gene.
Myocardial Infarction
Decrease in myocardial polyamine concentration in rats with myocardial infarction.
Myocardial Infarction
Endogenous ornithine decarboxylase/polyamine system mediated the antagonist role of insulin/PEG-CMCS preconditioning against heart ischemia/reperfusion injury in diabetes mellitus.
Myotonic Dystrophy
ZNF9 activation of IRES-mediated translation of the human ODC mRNA is decreased in myotonic dystrophy type 2.
Neoplasm Metastasis
Antimetastatic activity of DL-alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, in mice.
Neoplasm Metastasis
Cranberry and its phytochemicals: a review of in vitro anticancer studies.
Neoplasm Metastasis
Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis.
Neoplasm Metastasis
Effect of remedies for enhancing resistance and relieving blood stasis on metastasis in postoperative gastric cancer and ornithine decarboxylase levels.
Neoplasm Metastasis
Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice.
Neoplasm Metastasis
Increased expression of ornithine decarboxylase messenger RNA in human esophageal carcinoma.
Neoplasm Metastasis
Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment.
Neoplasm Metastasis
Methylglyoxal-bis(guanylhydrazone) in hormone-resistant adenocarcinoma of the prostate.
Neoplasm Metastasis
Ornithine decarboxylase activity as a prognostic marker for colorectal cancer.
Neoplasm Metastasis
Ornithine decarboxylase activity in hepatic and extrahepatic metastases from colorectal cancer.
Neoplasm Metastasis
Ornithine decarboxylase inhibitor attenuates bombesin enhancement of intestinal carcinogenesis and metastasis induced by azoxymethane.
Neoplasm Metastasis
Ornithine decarboxylase overexpression in mouse 10T1/2 fibroblasts: cellular transformation and invasion.
Neoplasm Metastasis
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
Neoplasm Metastasis
Polyamine metabolism and recurrence after resection for hepatocellular carcinoma.
Neoplasm Metastasis
Relationship of polyamine metabolism to degree of malignancy of human hepatocellular carcinoma.
Neoplasm Metastasis
The effects of Chinese drugs for supporting healthy energy and removing blood stasis on postoperative metastasis of gastric carcinoma and ornithine decarboxylase.
Neoplasm Metastasis
Translation of ODC mRNA and polyamine transport are suppressed in ras-transformed CREF cells by depleting translation initiation factor 4E.
Neoplasm Metastasis
Treatment of metastatic Lewis lung carcinoma with DL-alpha-difluoromethylornithine.
Neoplasm Metastasis
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines.
Neoplasm Metastasis
[A ornithine decarboxylase activity and proliferating cell nuclear antigen in gastric cancer]
Neoplasm Metastasis
[Reversion of malignant phenotypes of human lung squamous carcinoma cells by ornithine decarboxylase antisense RNA]
Neoplasms
(-)-Epigallocatechin-3-gallate in Camellia sinensis leaves from Himalayan region of Sikkim: inhibitory effects against biochemical events and tumor initiation in Sencar mouse skin.
Neoplasms
1,2-Dimethylhydrazine-induced alterations in N1-acetylspermidine levels in rat distal colonic mucosa: effects of 2-difluoromethylornithine.
Neoplasms
12-O-tetradecanoylphorbol-13-acetate actions on macromolecular synthesis, ornithine decarboxylase, and cellular differentiation of the rat embryonic visceral yolk sac in culture.
Neoplasms
12-O-tetradecanoylphorbol-13-acetate promotes tumors prior to initiation in two-stage promotion.
Neoplasms
4 Beta- and 4 alpha-12-O-tetradecanoylphorbol-13-acetate elicit arachidonate release from epidermal cells through different mechanisms.
Neoplasms
?-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY.
Neoplasms
A comprehensive strategy to combat colon cancer targeting the adenomatous polyposis coli tumor suppressor gene.
Neoplasms
A factor responsible for increases in ornithine decarboxylase activity in the livers of tumor-bearing mice.
Neoplasms
A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients.
Neoplasms
A mechanistic study of cigarette smoke and cyclooxygenase-2 on proliferation of gastric cancer cells.
Neoplasms
A novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR.
Neoplasms
A phase I and pharmacokinetic study of SAM486A, a novel polyamine biosynthesis inhibitor, administered on a daily-times-five every-three-week schedule in patients with Advanced solid malignancies.
Neoplasms
A polyamine pathway-mediated mitogenic mechanism in enterochromaffin-like cells of Mastomys.
Neoplasms
A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development.
Neoplasms
A review of gene-drug interactions for nonsteroidal anti-inflammatory drug use in preventing colorectal neoplasia.
Neoplasms
A role for protein kinase C-delta in the regulation of ornithine decarboxylase expression by oxidative stress.
Neoplasms
A survey of transformation markers in differentiating epidermal cell lines in culture.
Neoplasms
Ability of m-chloroperoxybenzoic acid to induce the ornithine decarboxylase marker of skin tumor promotion and inhibition of this response by gallotannins, oligomeric proanthocyanidins, and their monomeric units in mouse epidermis in vivo.
Neoplasms
Ability of tannins extracted from the leaves of various trees and shrubs to inhibit the biomarkers of tumor promotion in mouse skin in vivo.
Neoplasms
Ability of the Ca2+ ionophores A23187 and ionomycin to mimic some of the effects of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate on hydroperoxide production, ornithine decarboxylase activity, and DNA synthesis in mouse epidermis in vivo.
Neoplasms
Ability of the non-phorbol ester-type tumor-promoter thapsigargin to mimic the stimulatory effects of 12-0-tetradecanoylphorbol-13-acetate on ornithine decarboxylase activity, hydroperoxide production, and macromolecule synthesis in mouse epidermis in vivo.
Neoplasms
Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility.
Neoplasms
Abrogation of potassium bromate-induced renal oxidative stress and subsequent cell proliferation response by soy isoflavones in Wistar rats.
Neoplasms
Abrogation of thioacetamide-induced biochemical events of hepatic tumor promotion stage by tannic acid in Wistar rats.
Neoplasms
Absence of synergistic effects on tumor promotion in CD-1 mouse skin by simultaneous applications of two different types of tumor promoters, okadaic acid and teleocidin.
Neoplasms
Activation of human squamous cell carcinoma ornithine decarboxylase activity by guanosine triphosphate.
Neoplasms
Activation of mouse epidermal tumor ornithine decarboxylase by GTP: evidence for different catalytic forms of the enzyme.
Neoplasms
Activation of protein kinase C and specific phosphorylation of a Mr 90,000 membrane protein of promotable BALB/3T3 and C3H/10T1/2 cells by tumor promoters.
Neoplasms
Activity of ornithine decarboxylase (ODC) and polyamine levels as biochemical markers of malignancy in human brain tumors.
Neoplasms
Adenovirus-mediated expression of both antisense ornithine decarboxylase and S-adenosylmethionine decarboxylase inhibits lung cancer cell growth.
Neoplasms
All-trans beta-carotene enhances mitogenic responses and ornithine decarboxylase activity of BALB/c 3T3 fibroblast cells induced by tumor promoter and fetal bovine serum but suppresses mutagen-dependent umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002).
Neoplasms
all-trans-Retinoic acid inhibits the appearance of two phorbol ester-induced ornithine decarboxylase mRNAs in mouse epidermis.
Neoplasms
alpha-difluoromethylornithine induces apoptosis as well as anti-angiogenesis in the inhibition of tumor growth and metastasis in a human gastric cancer model.
Neoplasms
alpha-Difluoromethylornithine inhibits cell growth stimulated by a tumor-promoting rat urinary fraction.
Neoplasms
alpha-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin.
Neoplasms
Alpha-difluoromethylornithine-induced inhibition of growth of autochthonous experimental colonic tumors produced by azoxymethane in male F344 rats.
Neoplasms
Alterations in ornithine decarboxylase activity in the rat mammary gland after different periods of 50 Hz magnetic field exposure.
Neoplasms
Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis.
Neoplasms
Alternative splicing facilitates internal ribosome entry on the ornithine decarboxylase mRNA.
Neoplasms
Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors.
Neoplasms
Aminoglutethimide, a steroidogenesis inhibitor, abolishes hormonal induction of ornithine decarboxylase in steroidogenic tissues: evidence for its role as cAMP-dependent protein kinase inhibitor.
Neoplasms
Aminoguanidine reversal of the inhibitory effects of ornithine analogs on the in vitro clonogenic survival of the R3327AT prostate-derived tumor.
Neoplasms
Amplification of N-myc and ornithine decarboxylase genes in human neuroblastoma and hydroxyurea-resistant hamster cell lines.
Neoplasms
AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.
Neoplasms
An assessment of proliferative and enzyme activity in transitional mucosa adjacent to colonic cancer.
Neoplasms
Analysis of ornithine decarboxylase messenger ribonucleic acid expression in colorectal carcinoma.
Neoplasms
Androgen induces ornithine decarboxylase gene expression in colonic cell line HT-29.
Neoplasms
Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells.
Neoplasms
Anti-tumor activity of antizyme which targets the ornithine decarboxylase (ODC) required for cell growth and transformation.
Neoplasms
Anti-tumor promoting action of phthalic acid mono-n-butyl ester cupric salt, a biomimetic superoxide dismutase.
Neoplasms
Anticancer action of cubé insecticide: correlation for rotenoid constituents between inhibition of NADH:ubiquinone oxidoreductase and induced ornithine decarboxylase activities.
Neoplasms
Anticarcinogenic effect of Nymphaea alba against oxidative damage, hyperproliferative response and renal carcinogenesis in Wistar rats.
Neoplasms
Antiinflammatory drug effects on ultraviolet light-induced epidermal ornithine decarboxylase and DNA synthesis.
Neoplasms
Antiproliferative effect of spermine depletion by N-cyclohexyl-1,3-diaminopropane in human breast cancer cells.
Neoplasms
Antitumor effect of antisense ornithine decarboxylase adenovirus on human lung cancer cells.
Neoplasms
Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin.
Neoplasms
Antitumor-promoting activities of tannic acid, ellagic acid, and several gallic acid derivatives in mouse skin.
Neoplasms
Antitumor-promoting activity of oligomeric proanthocyanidins in mouse epidermis in-vivo.
Neoplasms
Antitumor-promoting effects of gallotannins extracted from various sources in mouse skin in vivo.
Neoplasms
Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis.
Neoplasms
APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse.
Neoplasms
Assessment of ornithine decarboxylase activity in rectal mucosa as a marker for colorectal adenomas and carcinomas.
Neoplasms
Association among an ornithine decarboxylase polymorphism, androgen receptor gene (CAG) repeat length and prostate cancer risk.
Neoplasms
Association between high levels of ornithine decarboxylase activity and favorable prognosis in human colorectal carcinoma.
Neoplasms
Association between the ornithine decarboxylase G316A polymorphism and breast cancer survival.
Neoplasms
Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival.
Neoplasms
Attenuating effect of ornithine decarboxylase inhibitor (1,3-diaminopropane) on bombesin enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.
Neoplasms
Attenuation of benzoyl peroxide-mediated cutaneous oxidative stress and hyperproliferative response by the prophylactic treatment of mice with spearmint (Mentha spicata).
Neoplasms
Attenuation of oxidative stress, inflammation and early markers of tumor promotion by caffeic acid in Fe-NTA exposed kidneys of Wistar rats.
Neoplasms
Attenuation of vasoactive intestinal peptide enhancement of colon carcinogenesis by ornithine decarboxylase inhibitor.
Neoplasms
Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase.
Neoplasms
Basic fibroblast growth factor selectively regulates ornithine decarboxylase gene expression in malignant H-ras transformed cells.
Neoplasms
Benefits of complete polyamine deprivation in hormone responsive and hormone resistant MCF-7 human breast adenocarcinoma in vivo.
Neoplasms
beta-Carotene inhibits rectal mucosal ornithine decarboxylase activity in colon cancer patients.
Neoplasms
Bifidobacterium longum, a lactic acid-producing intestinal bacterium inhibits colon cancer and modulates the intermediate biomarkers of colon carcinogenesis.
Neoplasms
Bile acids, ornithine decarboxylase, and cell proliferation in colon cancer: a review.
Neoplasms
Biochemical markers in colorectal cancer: diagnostic and therapeutic implications.
Neoplasms
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Neoplasms
Butea monosperma and chemomodulation: protective role against thioacetamide-mediated hepatic alterations in Wistar rats.
Neoplasms
Celecoxib and difluoromethylornithine in combination have strong therapeutic activity against UV-induced skin tumors in mice.
Neoplasms
Cell cycle distribution and ornithine decarboxylase activity in head and neck cancer in response to enteral nutrition.
Neoplasms
Cell kinetics and polyamine enzymes in the intestinal mucosa of rats with azoxymethane induced tumours.
Neoplasms
Chain-fluorinated polyamines as tumor markers--I. In vivo transformation of 2,2-difluoroputrescine into 6,6-difluorospermidine and 6,6-difluorospermine.
Neoplasms
Chain-fluorinated polyamines as tumour markers. III. Determination of geminal difluoropolyamines and their precursor 2,2-difluoroputrescine in normal tissues and experimental tumours by in vitro and in vivo 19F NMR spectroscopy.
Neoplasms
Changes in expression of cellular oncogenes and endogenous retrovirus-like sequences during hepatocarcinogenesis induced by a peroxisome proliferator.
Neoplasms
Changes in expression of oncogenes and endogenous retroviral-like sequences during colon carcinogenesis.
Neoplasms
Changes in ornithine decarboxylase activity in normal tissues of tumor-bearing mice during tumor growth.
Neoplasms
Changes in the polyamine and nucleotide metabolism of P388 leukemia cells treated with DL-alpha-difluoromethylornithine in culture.
Neoplasms
Characterization of difluoromethylornithine-resistant mouse and human tumour cell lines.
Neoplasms
Characterization of novel phorbol ester- and serum-responsive sequences of the rat ornithine decarboxylase gene promoter.
Neoplasms
Characterization of the antitumor-promoting activity of camptothecin in SENCAR mouse skin.
Neoplasms
Characterization of the hydroperoxide response observed in mouse skin treated with tumor promoters in vivo.
Neoplasms
Characterization of the induction of ornithine decarboxylase activity by benzoyl peroxide in SENCAR mouse epidermis.
Neoplasms
Characterization of the tumor-promoting activity of m-chloroperoxybenzoic acid in SENCAR mouse skin and its inhibition by gallotannin, oligomeric proanthocyanidin, and their monomeric units.
Neoplasms
Characterization of the tumor-promoting activity of thapsigargin in cf-1 mouse skin.
Neoplasms
Chemomodulatory effect of Ficus racemosa extract against chemically induced renal carcinogenesis and oxidative damage response in Wistar rats.
Neoplasms
Chemomodulatory effects of Terminalia chebula against nickel chloride induced oxidative stress and tumor promotion response in male Wistar rats.
Neoplasms
Chemoprevention by amiloride of experimental carcinogenesis in rat colon induced by azoxymethane.
Neoplasms
Chemopreventive effects of alpha-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless mice.
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Chemopreventive effects of pomegranate seed oil on skin tumor development in CD1 mice.
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Chemopreventive effects of various concentrations of alpha-santalol on skin cancer development in CD-1 mice.
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Chlorpheniramine inhibits the ornithine decarboxylase induction of Ehrlich carcinoma growing in vivo.
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Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and the proliferation of human breast cancer cell lines.
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Cholesterol sulfate, a second messenger for the eta isoform of protein kinase C, inhibits promotional phase in mouse skin carcinogenesis.
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Chronic stress decreases ornithine decarboxylase expression and protects against 1,2-dimethylhydrazine-induced colon carcinogenesis.
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Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-?B.
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Cirsimaritin, a lung squamous carcinoma cells (NCIH-520) proliferation inhibitor.
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Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin.
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Colorectal ornithine decarboxylase activity in human mucosa and tumors: elevation of enzymatic activity in distal mucosa.
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Combining polyamine depletion with radiation therapy for rapidly dividing head and neck tumors: strategies for improved locoregional control.
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Comparison of enhancement of GGTase-positive foci and induction of ornithine decarboxylase in rat liver by barbiturates.
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Comparison of epidermal protein kinase C activity, ornithine decarboxylase induction and DNA synthesis stimulated by TPA or dioctanoylglycerol in mouse strains with differing susceptibility to TPA-induced tumor promotion.
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Comparison of some biochemical properties of epidermis in tumor promotion-susceptible and -resistant strains of mice.
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Comparison of the effect of sn-1,2-didecanoylglycerol and 12-O-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD-1 mice.
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Comparison of the effects of an ornithine decarboxylase inhibitor on the intestinal epithelium and on intestinal tumors.
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Comparison of the inhibitory effects of diverse amino acids and amino acid analogs on 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in isolated epidermal cells.
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Comparison of the inhibitory effects of monomeric, dimeric, and trimeric procyanidins on the biochemical markers of skin tumor promotion in mouse epidermis in vivo.
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Comparison of the skin tumor-promoting potential of different organic peroxides in SENCAR mice.
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Comparison of ultraviolet light-induced skin carcinogenesis and ornithine decarboxylase activity in sencar and hairless SKH-1 mice fed a constant level of dietary lipid varying in corn and coconut oil.
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Complex regulation of prothymosin alpha in mammary tumors arising arising in transgenic mice.
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Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells.
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Conjugated linoleic acid modulation of phorbol ester-induced events in murine keratinocytes.
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Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats.
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Control by hyperthermia of ornithine decarboxylase in Ehrlich ascites tumor cells.
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Control by treatment with lithium chloride of ornithine decarboxylase in Ehrlich ascites tumor cells.
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Conversion of C57Bl/6 mice from a tumor promotion-resistant to a -sensitive phenotype by enhanced ornithine decarboxylase expression.
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Copenhagen rat prostatic tumor ornithine decarboxylase activity (ODC) and the effect of the ODC inhibitor alpha-difluoromethylornithine.
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Correlation of phorbol ester promotion in the resistant C57BL/6J mouse with sustained hyperplasia but not ornithine decarboxylase or protein kinase C.
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Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.
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Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells.
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Critical roles of Myc-ODC axis in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 V617F mutant.
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Cubé resin insecticide: identification and biological activity of 29 rotenoid constituents.
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Curcumin induces apoptosis through an ornithine decarboxylase-dependent pathway in human promyelocytic leukemia HL-60 cells.
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Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies.
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Cyclic AMP and tumor promoters cause differential induction of ornithine decarboxylase and accumulation of putrescine in Chinese hamster ovary cells deficient in cyclic AMP-dependent protein kinase.
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Cytocidal effect of alpha-methylornithine, a competitive inhibitor of ornithine decarboxylase, on ehrlich ascites tumor cells in vivo.
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Cytokine regulation of gut ornithine decarboxylase gene expression and enzyme activity.
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Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model.
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Decarboxylated-S-adenosylmethionine excretion: a biochemical marker of ornithine decarboxylase inhibition by alpha-difluoromethylornithine.
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Decrease in ornithine decarboxylase activity after eradication of Helicobacter pylori.
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Degree of enhancement of polyamine biosynthetic decarboxylase activities in human tumors: a useful new index of degree of malignancy.
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Degrees of malignancy in human primary central nervous system tumors: ornithine decarboxylase levels as better indicators than adenosylmethionine decarboxylase levels.
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Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes.
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Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors.
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Detection of ornithine decarboxylase gene expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin using in situ hybridization.
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Detection of ornithine decarboxylase messenger RNA in human hepatocellular carcinoma by in situ hybridization.
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Detection of ornithine decarboxylase mRNA in human breast cancer MCF-7 cells by in situ RT-PCR.
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Determination of free and total polyamines in human serum and urine by ion-pairing high-performance liquid chromatography using a radial compression module. Application to blood polyamine determination in cancer patients treated or not treated with an ornithine decarboxylase inhibitor.
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Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resistance protein, prostaglandin E synthetase, and glutathione-S-transferase-alpha (GST)-alpha, GST-mu, and GST-pi.
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Development of phorbol ester responsiveness in neonatal mouse epidermis: correlation between hyperplastic response and sensitivity to first-stage tumor promotion.
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Development of TNKase-specific cleavable peptide-linked radioimmunoconjugates for radioimmunotherapy.
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Developmental toxicity studies of 2-(difluoromethyl)-dl-ornithine (DFMO) in rats and rabbits.
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DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27Kip1 activity in neuroblastoma.
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Dietary conjugated linoleic acid induces peroxisome-specific enzyme accumulation and ornithine decarboxylase activity in mouse liver.
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Dietary protein enhanced mammary ornithine decarboxylase activity and tumorigenesis in rats.
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Differential androgen sensitivity is associated with clonal heterogeneity in steroid metabolism, ornithine decarboxylase regulation and IL-1alpha action in mouse mammary tumor cells.
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Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: association with epidermal hyperplasia and tumor promotion.
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Differential effect of interferon on DNA synthesis, 2-deoxyglucose uptake and ornithine decarboxylase activity in 3T3 cells stimulated by polypeptide growth factors and tumor promotors.
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Differential effects of cyclosporine A on ornithine decarboxylase activity induced by ultraviolet-B and PUVA in mouse skin.
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Differential effects of polyamine homologues on the prevention of DL-alpha-difluoromethylornithine-mediated inhibition of malignant cell growth and normal immune response.
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Differential expression of ornithine decarboxylase antizyme inhibitors and antizymes in rodent tissues and human cell lines.
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Differential gene expression revealed with RNA-Seq and parallel genotype selection of the ornithine decarboxylase gene in fish inhabiting polluted areas.
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Differential inhibition by staurosporine, a potent protein kinase C inhibitor, of 12-O-tetradecanoylphorbol-13-acetate-caused skin tumor promotion, epidermal ornithine decarboxylase induction, hyperplasia and inflammation.
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Differential retinoic acid inhibition of ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate and by germicidal ultraviolet light.
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Difluoromethylornithine and leukocyte interferon: a phase I study in cancer patients.
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Difluoromethylornithine chemoprevention of epidermal carcinogenesis in K14-HPV16 transgenic mice.
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Difluoromethylornithine Combined with a Polyamine Transport Inhibitor Is Effective against Gemcitabine Resistant Pancreatic Cancer.
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Difluoromethylornithine-induced amplification of ornithine decarboxylase genes in Ehrlich ascites carcinoma cells.
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Dissimilar activation patterns of the carcinogen dimethylhydrazine (DMH) on intracellular polyamine metabolism in various organs.
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Dissociation of increases in levels of 3':5'-cyclic AMP and 3':5'-cyclic GMP from induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in mouse epidermis in vivo.
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Dissociation of tumor promoter-stimulated ornithine decarboxylase activity and DNA synthesis in mouse epidermis in vivo and in vitro by fluocinolone acetonide, a tumor-promotion inhibitor.
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DNA methylation is not involved in the structural alterations of ornithine decarboxylase or total chromatin of c-Ha-rasVal 12 oncogene-transformed NIH-3T3 fibroblasts.
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Dose and schedule of oral retinoic acid and indomethacin needed to effectively inhibit phorbol ester-induced epidermal ornithine decarboxylase activity.
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Downregulation of tumstatin expression by overexpression of ornithine decarboxylase.
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Effect of 1,8-dihydroxy-9-anthrone (anthralin) on rat hepatic ornithine decarboxylase activity in vivo.
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Effect of acylated derivatives of ascorbate on ornithine decarboxylase induction in Ehrlich ascites tumor cells.
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Effect of Aegle marmelos on DEN initiated and 2-AAF promoted hepatocarcinogenesis: a chemopreventive study.
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Effect of alpha-difluoromethyl ornithine on the transplantable rat hepatoma 5123, 1-1.
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Effect of androgen on ornithine decarboxylase activity in androgen-dependent mouse mammary tumor (Shionogi Carcinoma 115) and its androgen-independent subline (CS 2).
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Effect of application frequency on epidermal ornithine decarboxylase induction by chrysarobin in SENCAR mice.
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Effect of beta-carotene supplementation on the activity of ornithine decarboxylase (ODC) in stomach mucosa of patients with chronic atrophic gastritis.
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Effect of calvatic acid and its analogs on ornithine decarboxylase activity in tumour cells.
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Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models.
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Effect of dietary conjugated linoleic acid on phorbol ester-induced PGE2 production and hyperplasia in mouse epidermis.
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Effect of diethylstilbestrol on the transformable mouse embryo fibroblast C3H/10T1/2C18 cells. Tumor promotion, cell growth, DNA synthesis, and ornithine decarboxylase.
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Effect of different levels of calorie restriction on azoxymethane-induced colon carcinogenesis in male F344 rats.
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Effect of difluoromethylornithine on host and tumor polyamine metabolism during total parenteral nutrition.
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Effect of elevated levels of ornithine decarboxylase on cell cycle progression in skin.
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Effect of green tea extract on the induction of ornithine decarboxylase and the activation of extracellular signal-regulated kinase in bladder carcinoma ECV304 cells.
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Effect of inhibition of polyamine biosynthesis by DL-alpha-difluoromethylornithine on the growth and melanogenesis of B16 melanoma in vitro and in vivo.
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Effect of intravenous alpha-difluoromethylornithine on the polyamine levels of normal tissue and a transplantable fibrosarcoma.
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Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats.
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Effect of parathyroid hormone related protein, and dihydrotestosterone on proliferation and ornithine decarboxylase mRNA in human prostate cancer cell lines.
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Effect of polyamine deprivation on the survival of intracranial glioblastoma bearing rats.
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Effect of polyamine metabolism inhibitors on Lewis lung carcinoma growth and metastasis.
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Effect of polycyclic aromatic compounds and phorbol esters on ornithine decarboxylase and aryl hydrocarbon hydroxylase activities in mouse liver.
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Effect of progressive neoplastic growth on the decarboxylation of DL-[1-14C]ornithine by lymphocytes from C3H/He tumor hosts.
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Effect of remedies for enhancing resistance and relieving blood stasis on metastasis in postoperative gastric cancer and ornithine decarboxylase levels.
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Effect of tamoxifen and D,L-2-difluoromethylornithine on the growth, ornithine decarboxylase activity and polyamine content of mammary carcinomas induced by 1-methyl-1-nitrosourea.
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Effect of tamoxifen on 1,2-dimethylhydrazine-HCl-induced colon carcinogenesis in rats.
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Effects of a biomimetic superoxide dismutase on complete and multistage carcinogenesis in mouse skin.
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Effects of alpha-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) on the growth of experimental renal adenocarcinoma in mice.
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Effects of alpha-difluoromethylornithine and recombinant interferon-alpha 2 on the growth of a human renal cell adenocarcinoma xenograft in nude mice.
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Effects of amino acid treatments on 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis in vivo and in vitro.
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Effects of an antitumoural rhodium complex on thioacetamide-induced liver tumor in rats. Changes in the activities of ornithine decarboxylase, tyrosine aminotransferase and of enzymes involved in fatty acid and glycerolipid synthesis.
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Effects of butylated hydroxyanisole on ornithine decarboxylase activity and its gene expression induced by phorbol ester tumor promoter.
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Effects of butylated hydroxyanisole on ornithine decarboxylase activity induced by ultraviolet-B and PUVA in mouse skin.
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Effects of butylated hydroxytoluene upon PUVA-tumorigenesis and induction of ornithine decarboxylase activity in the mouse.
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Effects of colchicine on the induction of ornithine decarboxylase and its gene expression by the phorbol ester tumour promoter.
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Effects of combined treatments with selenium, glutathione, and vitamin E on glutathione peroxidase activity, ornithine decarboxylase induction, and complete and multistage carcinogenesis in mouse skin.
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Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
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Effects of D,L-2-difluoromethylornithine and indomethacin on mammary tumor promotion in rats fed high n-3 and/or n-6 fat diets.
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Effects of difluoromethylornithine on growth inhibition and apoptosis in human cervical epithelial and cancerous cell lines.
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Effects of diverse intracellular thiol delivery agents on glutathione peroxidase activity, the ratio of reduced/oxidized glutathione, and ornithine decarboxylase induction in isolated mouse epidermal cells treated with 12-O-tetradecanoylphorbol-13-acetate.
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Effects of DL-alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, on the rat mammary tumour induced by 7,12-dimethylbenz[a]anthracene.
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Effects of dose and duration of treatment with the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate on mouse skin carcinogenesis.
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Effects of flavonoids and antioxidants on 12-O-tetradecanoyl-phorbol-13-acetate-caused epidermal ornithine decarboxylase induction and tumor promotion in relation to lipoxygenase inhibition by these compounds.
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Effects of garlic and onion oils on glutathione peroxidase activity, the ratio of reduced/oxidized glutathione and ornithine decarboxylase induction in isolated mouse epidermal cells treated with tumor promoters.
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Effects of methylacetylenic putrescine, an ornithine decarboxylase inhibitor and potential novel anticancer agent, on human and mouse cancer cell lines.
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Effects of overexpression of ornithine decarboxylase (ODC) on growth control and oncogene-induced cell transformation.
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Effects of psoralen from Psoralea corylifolia on quinone reductase, ornithine decarboxylase, and JB6 cells transformation promotion.
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Effects of timing of administration and dose of difluoromethylornithine on rat colonic carcinogenesis.
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Effects of treatments with alpha-difluoromethylornithine and hyperthermia on the growth and polyamine metabolism of Harding-Passey murine melanoma.
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Effects of tumor-promoting phorbol diesters on neoplastic progression of Syrian hamster embryo cells.
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Effects of ultraviolet-B and PUVA on ornithine decarboxylase activity, DNA synthesis, and protein kinase C activity in mouse skin.
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Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.
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Ehrlich ascites tumour cells become refractory to alpha-difluoromethylornithine at a certain stage of growth.
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Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids.
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Elevated expression of the ornithine decarboxylase gene in human esophageal cancer.
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Elevated levels of polyamines alter chromatin in murine skin and tumors without global changes in nucleosome acetylation.
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Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites.
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Elevated ornithine decarboxylase activity, polyamines and cell proliferation in neoplastic and vacuolated liver cells of winter flounder (Pleuronectes americanus)
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Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (-)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice.
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Elevation in putrescine level and spermidine/spermine N1-acetyltransferase activity coincide with tumor development in 1, 2-dimethylhydrazine-induced rat colon.
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Emerging concepts in targeting the polyamine metabolic pathway in epithelial cancer chemoprevention and chemotherapy.
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Endogenous tumor growth factor indicated by increased ornithine decarboxylase activity in malignant cells treated with host serum ascites fluid.
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Enhanced induction of epidermal ornithine decarboxylase activity in C57BL/6 compared to DBA/2 mice by protein kinase C-activating skin tumor promoters: relevance to genetically mediated differences in promotion susceptibility.
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Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene.
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Enhanced Sp1 DNA-binding activity in murine keratinocyte cell lines and epidermal tumors.
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Enhancement by adriamycin of the effects of 12-O-tetradecanoylphorbol-13-acetate on mouse epidermal glutathione peroxidase activity, ornithine decarboxylase induction and skin tumor promotion.
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Enhancement of biliary excretion of aflatoxin B(1) and suppression of hepatic ornithine decarboxylase activity by 2-(allylthio)pyrazine in rats.
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Enhancing effect of ultraviolet A on ornithine decarboxylase induction and dermatitis evoked by 12-o-tetradecanoylphorbol-13-acetate and its inhibition by curcumin in mouse skin.
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Epidermal growth factor receptor expression in cervical intraepithelial neoplasia and its modulation during an alpha-difluoromethylornithine chemoprevention trial.
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Epidermal ornithine decarboxylase and polyamines in mice exposed to 50 Hz magnetic fields and UV radiation.
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Epidermal ornithine decarboxylase induction and mouse skin tumor promotion by quinones.
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Epidermal ornithine decarboxylase, polyamines, cell proliferation, and tumor promotion.
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Epidermal pyridoxal 5'-phosphate depletion, inhibition of DNA synthesis, and inhibition of the expression of ornithine decarboxylase activity by the vitamin B-6 antagonist 4'-deoxypyridoxine.
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Estimation of tumor promoting activity and structure-function relationships of aplysiatoxins.
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Estradiol is trophic for colon cancer in mice: effect on ornithine decarboxylase and c-myc messenger RNA.
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Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis.
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Evaluation of ornithine decarboxylase activity as a marker for tumor growth rate in malignant tumors.
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Evaluation of possible mechanisms of protective role of Tamarix gallica against DEN initiated and 2-AAF promoted hepatocarcinogenesis in male Wistar rats.
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Evaluation of selected lichens from iceland for cancer chemopreventive and cytotoxic activity.
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Evaluation of the potential of cancer chemopreventive activity mediated by inhibition of 12-O-tetradecanoyl phorbol 13-acetate-induced ornithine decarboxylase activity.
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Events associated with mouse skin tumor promotion with respect to arachidonic acid metabolism: a comparison between SENCAR and NMRI mice.
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Experimental carcinogenesis in the rat intestine induced by two different carcinogens--evaluation of carcinogenic action and its effect on ornithine decarboxylase activity.
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Experimental chemotherapy in a transplantable renal adenocarcinoma. I: Effects of some inhibitors of polyamine synthesis.
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Expression of a novel human ornithine decarboxylase-like protein in the central nervous system and testes.
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Expression of epidermal ornithine decarboxylase and nuclear proto-oncogenes in phorbol ester tumor promotion-sensitive and -resistant mice.
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Expression patterns of ornithine decarboxylase and c-met in growing Yoshida AH-130 hepatoma.
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Extracellular polyamines-induced proliferation and migration of cancer cells by ODC, SSAT, and Akt1-mediated pathway.
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Ferric nitrilotriacetate (Fe-NTA) is a potent hepatic tumor promoter and acts through the generation of oxidative stress.
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Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress.
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Fibroblast growth factor and ornithine decarboxylase 5'UTRs enable preferential expression in human prostate cancer cells and in prostate tumors of PTEN(-/-) transgenic mice.
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Flow cytometric detection of ornithine decarboxylase activity in epidermal cell subpopulations.
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Free radical-derived quinone methide mediates skin tumor promotion by butylated hydroxytoluene hydroperoxide: expanded role for electrophiles in multistage carcinogenesis.
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Fusion of the HCMV pp65 antigen with both ubiquitin and ornithine decarboxylase additionally enhances antigen presentation to CD8+ T cells in human dendritic cells.
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Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: implications for cancer prevention.
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Gastric and oesophageal carcinogenesis: models for the identification of risk and protective factors.
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Gene expression of ornithine decarboxylase in lung cancers and its clinical significance.
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Gene polymorphisms in the ornithine decarboxylase-polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations.
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Genetic evidence that a phorbol ester tumor promoter stimulates ornithine decarboxylase activity by a pathway that is independent of cyclic AMP-dependent protein kinases in CHO cells.
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Genetically determined differences in the response to carcinogens of aryl hydrocarbon hydroxylase and ornithine decarboxylase.
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Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells.
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Germicidal ultraviolet light induces ornithine decarboxylase in mouse epidermal cells and modifies the induction caused by phorbol ester tumor promoters.
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Growth inhibition of a prostate tumor by alpha-difluoromethylornithine and by cyclophosphamide.
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Growth inhibitory effect of green tea extract in Ehrlich ascites tumor cells involves cytochrome c release and caspase activation.
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Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line.
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Growth-related enzyme activities in crypt compartments during rat colon carcinogenesis.
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Helicobacter pylori lipopolysaccharide alters ECL cell DNA synthesis via a CD14 receptor and polyamine pathway in mastomys.
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Hemin inhibits cyclooxygenase-2 expression through nuclear factor-kappa B activation and ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin.
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Hepatocyte growth factor-activated NF-kappaB regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines.
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Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.
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Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors.
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Heterogenicity of ornithine decarboxylase during mouse colon carcinogenesis and in human colon tumors.
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High ornithine decarboxylase activity and polyamine levels in human colorectal neoplasia.
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Histamine and serotonin inhibit induction of ornithine decarboxylase by ornithine in perifused Ehrlich ascites tumour cells.
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Human lung tumor sensitivity to difluoromethylornithine as related to ornithine decarboxylase messenger RNA levels.
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Human myeloma cells acquire resistance to difluoromethylornithine without overproducing ornithine decarboxylase.
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Human ornithine decarboxylase sequences map to chromosome regions 2pter----p23 and 7cen----qter but are not coamplified with the NMYC oncogene.
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Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase.
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Identification and applications of repetitive probes for gene mapping in the mouse.
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Identification of cembratriene-4,6-diol as antitumor-promoting agent from cigarette smoke condensate.
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Identification of differentially expressed genes in normal and tumor human gastric tissue.
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Identification of epidermal cell subpopulations with increased ornithine decarboxylase activity following treatment of murine epidermis with 12-O-tetradecanoylphorbol-13-acetate.
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Immunocytochemical detection of ornithine decarboxylase (ODC) in paraffin-embedded tissues as a possible prognostic indicator for oral lesions.
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Immunohistochemical detection of ornithine-decarboxylase in primary and metastatic human breast cancer specimens.
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Immunohistochemical expression of ornithine decarboxylase, diamine oxidase, putrescine, and spermine in normal canine enterocolic mucosa, in chronic colitis, and in colorectal cancer.
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In situ RT-PCR allows the detection of ornithine decarboxylase mRNA in paraffin embedded archival human hyperplastic breast tissues.
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In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase.
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In vitro chemosensitivity testing of hematological cancer patients: detection of ornithine decarboxylase.
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In vitro chemosensitivity testing of hematological cancers: immunohistochemical detection of ornithine decarboxylase.
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In vitro development and validation of a non-invasive (13)C-stable isotope assay for ornithine decarboxylase.
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In vitro induction of human skin ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
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In vivo exposure of rats to a weak alternating magnetic field increases ornithine decarboxylase activity in the mammary gland by a similar extent as the carcinogen DMBA.
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In vivo induction of rat hepatic ornithine decarboxylase and plasminogen activator by 12-O-tetradecanoylphorbol 13-acetate.
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Increase in ornithine decarboxylase activity associated with development of dysplasia in Barrett's esophagus.
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Increased expression of ornithine decarboxylase by gamma-ray in mouse epidermal cells: relationship with protein kinase C signaling pathway.
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Increased expression of ornithine decarboxylase messenger RNA in human esophageal carcinoma.
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Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase.
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Increased levels of phorbin, c-myc, and ornithine decarboxylase RNAs in human colon cancer.
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Increased mouse epidermal ornithine decarboxylase activity by the tumour promoter 12-O-tetradecanoylphorbol 13-acetate involves increased amounts of both enzyme protein and messenger RNA.
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Increased mucosal ornithine decarboxylase activity in large bowel with multiple tumors, adenocarcinoma, and adenoma.
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Increased ornithine decarboxylase activity in cultured cells exposed to low energy modulated microwave fields and phorbol ester tumor promoters.
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Increasing ornithine decarboxylase activity is another way of prolactin preventing methotrexate-induced apoptosis: crosstalk between ODC and BCL-2.
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Individual and combined effects of alpha-difluoromethylornithine and ovariectomy on the growth and polyamine milieu of experimental breast cancer in rats.
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Individual overexpression of five subunits of human translation initiation factor eIF3 promotes malignant transformation of immortal fibroblast cells.
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Induction by chloroform of two forms of ornithine decarboxylase in rat liver. Half-life of isozymes.
Neoplasms
Induction of epidermal ornithine decarboxylase activity in mouse skin exposed to biogenic silica fibers.
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Induction of histidine and ornithine decarboxylase activities in mouse tissues by recombinant interleukin-1 and tumor necrosis factor.
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Induction of mouse epidermal ornithine decarboxylase activity and skin tumors by 7,12-dimethylben.
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Induction of mouse epidermal ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate: dependence on calcium availability.
Neoplasms
Induction of ornithine decarboxylase activity and DNA synthesis in hairless mouse epidermis by retinoids.
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Induction of ornithine decarboxylase activity in epidermis by a tumor promoter: decreased response in mice maintained on a vitamin B6-deficient diet.
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Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis.
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Induction of ornithine decarboxylase and augmentation of tyrosine aminotransferase activity by N-hydroxy-2-acetylaminofluorene and 2-acetylaminofluorene in rat liver. Influence of sex, retinylacetate, indomethacin, and pentachlorophenol.
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Induction of ornithine decarboxylase by 12-O-tetradecanoylphorbol 13-acetate in hamster fibroblasts. Relationship between levels of enzyme activity, immunoreactive protein, and RNA during the induction process.
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Induction of ornithine decarboxylase in guinea-pig lymphocytes. Synergistic effect of diacylglycerol and calcium.
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Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate.
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Induction of ornithine decarboxylase, tyrosine aminotransferase, and thymidine kinase by glucocorticoid in isolated, perfused liver after tumor inoculation.
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Induction of rat hepatic ornithine decarboxylase by the tumor promotors 12-O-tetradecanoylphorbol-13-acetate and phenobarbital in vivo; effect of retinyl-acetate.
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Induction of rat kidney ornithine decarboxylase by nicotinamide without a concomitant increase in DNA synthesis.
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Induction of renal oxidative stress and cell proliferation response by ferric nitrilotriacetate (Fe-NTA): diminution by soy isoflavones.
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Induction of short-term biomarkers of tumor promotion in skin of CD-1 mice by petroleum middle distillates: preliminary observations.
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Induction of the polyamine-biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion.
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Inductions of ornithine decarboxylase and DNA synthesis in rat stomach mucosa by glandular stomach carcinogens.
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Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells.
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Influence of total parenteral nutrition on tumor growth and polyamine biosynthesis of fibrosarcoma-bearing rats after induced cachexia.
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Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis.
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Inhibition by 2(3)-tert-butyl-4-hydroxyanisole and other antioxidants of epidermal ornithine decarboxylase activity induced by 12-O-tetradecanoylphorbol-13-acetate.
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Inhibition by calmodulin antagonist trifluoperazine of experimental carcinogenesis in rat colon induced by azoxymethane.
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Inhibition by indomethacin and 5,8,11,14-eicosatetraynoic acid of the induction of rat hepatic ornithine decarboxylase by the tumor promoters phenobarbital and 12-O-tetradecanoylphorbol-13-acetate in vivo.
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Inhibition by lipoxygenase inhibitors of 7-bromomethylbenz[a]anthracene-caused epidermal ornithine decarboxylase induction and skin tumor promotion in mice.
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Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
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Inhibition by putrescine of experimental carcinogenesis in rat colon induced by azoxymethane.
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Inhibition by putrescine of the induction of epidermal ornithine decarboxylase activity and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
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Inhibition by retinoids of anthralin-induced mouse epidermal ornithine decarboxylase activity and anthralin-promoted skin tumor formation.
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Inhibition by squalene of the tumor-promoting activity of 12-O-tetradecanoylphorbol-13-acetate in mouse-skin carcinogenesis.
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Inhibition effect of miR-150 on the progression of oral squamous cell carcinoma by data analysis model based on independent sample T-test.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin ornithine decarboxylase and protein kinase C by polyphenolics from grapes.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate induction of ornithine decarboxylase activity, DNA synthesis, and tumor promotion in mouse skin by ascorbic acid and ascorbyl palmitate.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by geniposide.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity and tumor promotion by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) in mouse skin.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity by lipoxygenase inhibitors: possible role of product(s) of lipoxygenase pathway.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory skin edema and ornithine decarboxylase activity by theaflavin-3,3'-digallate in mouse.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and epidermal ornithine decarboxylase activity in mouse skin by palmitoylcarnitine.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and ornithine decarboxylase activity by quercetin: possible involvement of lipoxygenase inhibition.
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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-mediated epidermal ornithine decarboxylase induction and skin tumor promotion by new lipoxygenase inhibitors lacking protein kinase C inhibitory effects.
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Inhibition of DNA synthesis and sugar uptake and lack of induction of ornithine decarboxylase in human epidermal cells treated with mouse skin tumor promoters.
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Inhibition of EMT6 tumor growth by interference with polyamine biosynthesis; effects of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase.
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Inhibition of expression of ornithine decarboxylase by c-myc antisense oligonucleotide at the promotion stage of lung tumorigenesis in mice.
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Inhibition of methylnitrosourea-induced large bowel cancer development in rats by sarcophytol A, a product from a marine soft coral Sarcophyton glaucum.
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Inhibition of mouse bladder tumor proliferation by alpha difluoromethylornithine and interferon in vitro and in vivo.
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Inhibition of mouse skin tumor promotion and of promoter-induced epidermal polyamine biosynthesis by methylglyoxal bis(butylamidinohydrazone).
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Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by alpha-difluoromethylornithine.
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Inhibition of mouse skin tumor promotion by anti-inflammatory diarylheptanoids derived from Alpinia oxyphylla Miquel (Zingiberaceae).
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Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice.
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Inhibition of ornithine decarboxylase activity and cell growth by diamines: a comparison between the effects of two homologs, 1,3-diaminopropane and 1,4-diaminobutane (putrescine).
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Inhibition of ornithine decarboxylase activity by small doses of alpha-difluoromethylornithine.
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Inhibition of ornithine decarboxylase alters the roscovitine-induced mitochondrial-mediated apoptosis in MCF-7 breast cancer cells.
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Inhibition of ornithine decarboxylase with 2-difluoromethylornithine: reduced incidence of dimethylhydrazine-induced colon tumors in mice.
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Inhibition of phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate-caused inflammatory responses in SENCAR mouse skin by black tea polyphenols.
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Inhibition of phorbol ester--induced human epidermal ornithine decarboxylase activity by oral compounds: a possible role in human chemoprevention studies.
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Inhibition of phorbol ester-caused induction of ornithine decarboxylase and tumor promotion in mouse skin by staurosporine, a potent inhibitor of protein kinase C.
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Inhibition of phorbol ester-caused synthesis of mouse epidermal ornithine decarboxylase by retinoic acid.
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Inhibition of polyamine biosynthesis in Acanthamoeba castellanii and 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by chitosanoligosaccharide.
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Inhibition of Polyamine Biosynthesis Reverses Ca2+ Channel Remodeling in Colon Cancer Cells.
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Inhibition of polyamine oxidase improves the antitumoral effect of ornithine decarboxylase inhibitors.
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Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma.
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Inhibition of potassium bromate-induced renal oxidative stress and hyperproliferative response by Nymphaea alba in Wistar rats.
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Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine.
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Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives.
Neoplasms
Inhibition of skin tumor promotion by retinoic acid and its metabolite 5,6-epoxyretinoic acid.
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Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
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Inhibition of teleocidin-caused epidermal ornithine decarboxylase induction by phospholipase A2-, cyclooxygenase- and lipoxygenase-inhibitors.
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Inhibition of the growth of U-251 human glioblastoma in nude mice by polyamine deprivation.
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Inhibition of the induction of ornithine decarboxylase activity by 12-O-tetradecanoylphorbol-13-acetate in mouse skin by sphingosine sulfate.
Neoplasms
Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds.
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Inhibition of tumor promoter 12-O-tetradecanoylphorbol-13-acetate-induced synthesis of epidermal ornithine decarboxylase messenger RNA and diacylglycerol-promoted mouse skin tumor formation by retinoic acid.
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Inhibition of tumor promoter-induced ornithine decarboxylase activity by tannic acid and other polyphenols in mouse epidermis in vivo.
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Inhibition of tumor promotion by DL-alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase.
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Inhibition of tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by crocetin.
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Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome.
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Inhibition of two stage renal carcinogenesis, oxidative damage and hyperproliferative response by Nigella sativa.
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Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid.
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Inhibition of ultraviolet-B radiation induced ornithine decarboxylase activity and edema formation by hydrolyzable and condensed tannins in mouse skin in vivo.
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Inhibitors of polyamine biosynthesis block tumor necrosis factor-induced activation of macrophages.
Neoplasms
Inhibitory effect of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by baicalein.
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Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice.
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Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate.
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Inhibitory effect of dietary arginine on growth of Ehrlich ascites tumor cells in mice.
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Inhibitory effect of dietary perilla oil rich in the n-3 polyunsaturated fatty acid alpha-linolenic acid on colon carcinogenesis in rats.
Neoplasms
Inhibitory effect of silymarin, an anti-hepatotoxic flavonoid, on 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity and mRNA in SENCAR mice.
Neoplasms
Inhibitory effects of 1,3-diaminopropane, an ornithine decarboxylase inhibitor, on rat two-stage urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Neoplasms
Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis.
Neoplasms
Inhibitory effects of glutathione level-raising agents and D-alpha-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
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Inhibitory effects of semisynthetic flavonoid derivatives on the biochemical markers of tumor promotion in mouse epidermis in vivo.
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Inhibitory effects of soy isoflavones on rat prostate carcinogenesis induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Neoplasms
Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice.
Neoplasms
Inositol hexaphosphate reduces 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase independent of protein kinase C isoform expression in keratinocytes.
Neoplasms
Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma.
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Insulin and phorbol myristic acetate induce ornithine decarboxylase in Reuber H35 rat hepatoma cells by different mechanisms.
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Intracellular calcium and skin tumor promotion: calcium regulation of the induction of epidermal ornithine decarboxylase activity by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
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Investigation of co-amplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a DEAD box gene, DDX1, with N-myc in neuroblastoma. United Kingdom Children's Cancer Study Group.
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Involvement of histamine in growth of mouse and rat tumors: antitumoral properties of monofluoromethylhistidine, an enzyme-activated irreversible inhibitor of histidine decarboxylase.
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Involvement of prostaglandin E2 in bile acid-caused promotion of colon carcinogenesis and anti-promotion by the cyclooxygenase inhibitor indomethacin.
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Involvement of protein kinase C activation in ornithine decarboxylase gene expression in primary culture of newborn mouse epidermal cells and in skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
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Involvement of protein kinase C in the regulation of ornithine decarboxylase mRNA by phorbol esters in rat hepatoma cells.
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Involvement of protein kinase C in the transcriptional regulation of ornithine decarboxylase gene expression by 12-O-tetradecanoylphorbol-13-acetate in T24 human bladder carcinoma cells.
Neoplasms
Irreversible inhibition of the early increase in ornithine decarboxylase activity following growth stimulation is required to block Ehrlich ascites tumor cell proliferation in culture.
Neoplasms
Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-?/Smad signaling pathway.
Neoplasms
Kinetic changes in mucosal ornithine decarboxylase activity during azoxymethane-induced colonic carcinogenesis in the rat.
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L-arginine reduces cell proliferation and ornithine decarboxylase activity in patients with colorectal adenoma and adenocarcinoma.
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Lack of a protective effect of menhaden oil on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
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Lack of a role of DNA methylation in tumor promoter 12-O-tetradecanoylphorbol-13-acetate-induced synthesis of ornithine decarboxylase messenger RNA in T24 cells.
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Lack of effect of a 60 Hz magnetic field on biomarkers of tumor promotion in the skin of SENCAR mice.
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Lentiviral vector-mediated downregulation of ornithine decarboxylase inhibits tumor cell growth in vitro and in vivo.
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Levels of colorectal ornithine decarboxylase activity in patients with colon cancer, a family history of nonpolyposis hereditary colorectal cancer, and adenomas.
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Liver ornithine decarboxylase during phenobarbital promotion of nitrosamine carcinogenesis.
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Local anesthetics inhibit induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.
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Locally and systemically active glucocorticosteroids modify intestinal absorption of lipids in rats.
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Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer.
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Loss of murine tumor thymidine kinase activity in vivo following 5-fluorouracil (FUra) treatment by incorporation of FUra into RNA.
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Loss of p27Kip1 from cyclin E/cyclin-dependent kinase (CDK) 2 but not from cyclin D1/CDK4 complexes in cells transformed by polyamine biosynthetic enzymes.
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Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated tumor promotion in murine skin.
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Lupeol, a triterpene, inhibits early responses of tumor promotion induced by benzoyl peroxide in murine skin.
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Malignancy associated with ureterosigmoidostomy: detection by mucosa ornithine decarboxylase.
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Mechanism of hepatic ornithine decarboxylase induction by the ornithine decarboxylase-inducing factor isolated from tumor ascites fluid.
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Mechanism of hepatic ornithine decarboxylase induction by the ornithine decarboxylase-inducing factor isolated from tumor ascites fluid: determination of target cells for the factor in the liver.
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Mechanisms involved in ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate, a potent mouse skin tumor promoter and an activator of protein kinase C.
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Mechanisms mediating metabolic abnormalities in the livers of Ehrlich ascites tumor-bearing mice.
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Membrane Ca2+ fluxes in rat hepatoma cells exposed to a supraphysiological concentration of asparagine.
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Metabolism of Histone Deacetylase Proteins Opsonizes Tumor Cells to Checkpoint Inhibitory Immunotherapies.
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Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment.
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Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines.
Neoplasms
Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites.
Neoplasms
Modulation by adriamycin, daunomycin, verapamil, and trifluoperazine of the biochemical processes linked to mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Neoplasms
Modulation of adrenal ornithine decarboxylase by chlordecone, p,p'DDT and permethrin.
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Modulation of biologic endpoints by topical difluoromethylornithine (DFMO), in subjects at high-risk for nonmelanoma skin cancer.
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Modulation of HeLa cell phospholipid metabolism and ornithine decarboxylase activity by tumour promoters: regulation of response to phorbol-12,13-dibutyrate by receptor occupancy time.
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Modulation of L-Arginine-Arginase Metabolic Pathway Enzymes: Immunocytochemistry and mRNA Expression in Peripheral Blood and Tissue Levels in Head and Neck Squamous Cell Carcinomas in North East India.
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Modulation of mouse skin tumor promotion by dietary 13-cis-retinoic acid and alpha-difluoromethylornithine.
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Modulatory effect of Ficus racemosa: diminution of potassium bromate-induced renal oxidative injury and cell proliferation response.
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Modulatory effect of gentisic acid on the augmentation of biochemical events of tumor promotion stage by benzoyl peroxide and ultraviolet radiation in Swiss albino mice.
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Modulatory effects of Pluchea lanceolata against chemically induced oxidative damage, hyperproliferation and two-stage renal carcinogenesis in Wistar rats.
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Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances.
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Molecular mechanisms underlying anti-tumor promoting activities of heat-processed Panax ginseng C.A. Meyer.
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Mouse and human ornithine decarboxylase genes. Methylation polymorphism and amplification.
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Mouse skin chemical carcinogenesis is inhibited by antizyme in promotion-sensitive and promotion-resistant genetic backgrounds.
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Mucosal proliferation characteristics in ureterosigmoidostomy: effect of calcium supplement.
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Multi-omics analysis reveals that ornithine decarboxylase contributes to erlotinib resistance in pancreatic cancer cells.
Neoplasms
Multiple promoter elements govern expression of the human ornithine decarboxylase gene in colon carcinoma cells.
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Mutation of aspartate-233 to valine in mouse ornithine decarboxylase reduces enzyme activity.
Neoplasms
N-?-chloroacetyl-L-ornithine has in-vitro activity against cancer cell lines and in-vivo activity against ascitic and solid tumors.
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N-?-chloroacetyl-l-ornithine, a new competitive inhibitor of ornithine decarboxylase, induces selective growth inhibition and cytotoxicity on human cancer cells versus normal cells.
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New transition state-based inhibitor for human ornithine decarboxylase inhibits growth of tumor cells.
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NG-hydroxy-L-arginine and nitric oxide inhibit Caco-2 tumor cell proliferation by distinct mechanisms.
Neoplasms
Nitric oxide inhibits ornithine decarboxylase via S-nitrosylation of cysteine 360 in the active site of the enzyme.
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Nitric oxide mediates either proliferation or cell death in cardiomyocytes. Involvement of polyamines.
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Nitric oxide synthase inhibition promotes carcinogen-induced preneoplastic changes in the colon of rats.
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Non-AP-1 tumor promoter 12-O-tetradecanoylphorbol-13-acetate-responsive sequences in the human ornithine decarboxylase gene.
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Normal and malignant human urothelium: in vitro effects of epidermal growth factor.
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Novel drug discovery system for cancer stem cells in human squamous cell carcinoma of the esophagus.
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Novel patterns of gene expression in pituitary adenomas identified by complementary deoxyribonucleic acid microarrays and quantitative reverse transcription-polymerase chain reaction.
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Nutritional support and tumour growth in humans: A narrative review of the literature.
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Ochratoxin A-induced cell proliferation and tumor promotion in mouse skin by activating the expression of cyclin-D1 and cyclooxygenase-2 through nuclear factor-kappa B and activator protein-1.
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ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.
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ODC1 promotes proliferation and mobility via the AKT/GSK3?/?-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma.
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Of mice and men: a critical reappraisal of the two-stage theory of carcinogenesis.
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Ornithine Decarboxylase (ODC) Expression Pattern in Human Prostate Tissues and ODC Transgenic Mice.
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Ornithine decarboxylase activity and DNA synthesis after treatment of cells in culture with 12-O-tetradecanoylphorbol-13-acetate.
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Ornithine decarboxylase activity and DNA synthesis in primary and transformed hamster epidermal cells exposed to tumor promoter.
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Ornithine decarboxylase activity and polyamine content in adenocarcinomas of human stomach and large intestine.
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Ornithine decarboxylase activity and polyamine content in normal renal tissue and in renal carcinoma.
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Ornithine decarboxylase activity as a biochemical marker in individuals predisposed to lung cancer.
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Ornithine decarboxylase activity in foetal rat brain cells and in the mouse embryo fibroblasts C3H/10T1/2 CL8 cells: differences in response to medium change and to the tumor promoter TPA.
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Ornithine decarboxylase activity in mouse tumour tissue in response to refeeding and diet components.
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Ornithine decarboxylase activity in prostate and tumor: a feasibility study for PET with L-[5-14C]- and L-[5-14C]ornithine.
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Ornithine decarboxylase activity in tissues from rats exposed to 60 Hz magnetic fields, including harmonic and transient field characteristics.
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Ornithine decarboxylase activity in tumor and normal tissue of head and neck cancer patients.
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Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors.
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Ornithine decarboxylase activity, cell proliferation, and tumor promotion in mouse epidermis in vivo.
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Ornithine decarboxylase activity, prolactin blood levels, and estradiol and progesterone receptors in human breast cancer.
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Ornithine decarboxylase and glutamate decarboxylase 65 as prognostic markers of gallbladder malignancy: a clinicopathological study in benign and malignant lesions of the gallbladder.
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Ornithine decarboxylase assay in human colorectal mucosa. Methodologic issues of importance to quality control.
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Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells.
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Ornithine decarboxylase enzyme activity in human and hamster pancreatic tumor cell lines.
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Ornithine decarboxylase from mouse epidermis and epidermal papillomas: differences in enzymatic properties and structure.
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Ornithine decarboxylase gene expression is aberrantly regulated via the cAMP signal transduction pathway in malignant H-ras transformed cell lines.
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Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
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Ornithine decarboxylase in rat skin: 2. Differential response to hair plucking and a tumor promoter.
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Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters.
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Ornithine decarboxylase induction in rat colon: synergistic effects of intrarectal instillation of sodium deoxycholate and starvation-refeeding.
Neoplasms
Ornithine decarboxylase inhibition by alpha-difluoromethylornithine activates opposing signaling pathways via phosphorylation of both Akt/protein kinase B and p27Kip1 in neuroblastoma.
Neoplasms
Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer.
Neoplasms
Ornithine decarboxylase inhibitor attenuates bombesin enhancement of intestinal carcinogenesis and metastasis induced by azoxymethane.
Neoplasms
Ornithine decarboxylase inhibitors increase the cellular content of the enzyme: implications for translational regulation.
Neoplasms
Ornithine decarboxylase interferes with macrophage-like differentiation and matrix metalloproteinase-9 expression by tumor necrosis factor alpha via NF-kappaB.
Neoplasms
Ornithine decarboxylase is directly involved in mouse mammary carcinoma cell invasion in vitro.
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Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling.
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Ornithine decarboxylase lability in 2 transplantable highly deviated rat hepatomas.
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Ornithine decarboxylase levels in the rectal mucosa of patients with colonic neoplasia.
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Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer.
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Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells.
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Ornithine decarboxylase overexpression in mouse 10T1/2 fibroblasts: cellular transformation and invasion.
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Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
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Ornithine decarboxylase overexpression leads to increased epithelial tumor invasiveness.
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Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention.
Neoplasms
Ornithine decarboxylase prevents tumor necrosis factor alpha-induced apoptosis by decreasing intracellular reactive oxygen species.
Neoplasms
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
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Ornithine decarboxylase: a promising and exploratory candidate target for natural products in cancer chemoprevention.
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Ornithine decarboxylase: an unreliable marker for the identification of population groups at risk for colonic neoplasia.
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Ovarian dermoid cyst-associated autoimmune hemolytic anemia: a case report with emphasis on pathogenic mechanisms.
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Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation.
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Overexpression of ornithine decarboxylase enhances endothelial proliferation by suppressing endostatin expression.
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Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans.
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Overproduction of ornithine decarboxylase confers an apparent growth advantage to mouse tumor cells.
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Oxidation of retinol to retinoic acid as a requirement for biological activity in mouse epidermis.
Neoplasms
Palm oil alleviates 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion response in murine skin.
Neoplasms
Paradoxical effect of anthralin on 12-O-tetradecanoylphorbol-13-acetate-induced mouse epidermal ornithine decarboxylase activity, proliferation, and tumor promotion.
Neoplasms
Partial purificationand characterizationof a factor which stimulates an increase in ornithine decarboxylase activity in the liver from tumor cell-free ascites fluid.
Neoplasms
Perillyl alcohol as a protective modulator against rat hepatocarcinogenesis via amelioration of oxidative damage and cell proliferation.
Neoplasms
Peroxisome proliferator-activated receptor gamma and spermidine/spermine N1-acetyltransferase gene expressions are significantly correlated in human colorectal cancer.
Neoplasms
Persistence of the circadian variation and altered response to hepatectomy of hepatic ornithine decarboxylase activity with malignant tumor burden.
Neoplasms
Pharmacokinetic analysis by high-performance liquid chromatography of intravenous nordihydroguaiaretic acid in the mouse.
Neoplasms
Phase I chemoprevention study of difluoromethylornithine in subjects with organ transplants.
Neoplasms
Phase I dose de-escalation trial of alpha-difluoromethylornithine in patients with grade 3 cervical intraepithelial neoplasia.
Neoplasms
Phase I study of methylacetylenic putrescine, an inhibitor of polyamine biosynthesis.
Neoplasms
Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis.
Neoplasms
Phase I trial and pharmacokinetic study of intravenous and oral alpha-difluoromethylornithine.
Neoplasms
Phase I/II clinical trial of 2-difluoromethyl-ornithine (DFMO) and a novel polyamine transport inhibitor (MQT 1426) for feline oral squamous cell carcinoma.
Neoplasms
Phase II trial of recombinant interferon-alpha-2a and eflornithine in patients with recurrent glioma.
Neoplasms
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
Neoplasms
Platelet-derived growth factor mediated altered expression and regulation of ornithine decarboxylase in H-ras-transformed cell lines.
Neoplasms
Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer.
Neoplasms
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Neoplasms
Polyamine depletion by ODC-AdoMetDC antisense adenovirus impairs human colorectal cancer growth and invasion in vitro and in vivo.
Neoplasms
Polyamine deprivation prevents the development of tumour-induced immune suppression.
Neoplasms
Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells.
Neoplasms
Polyamine levels and ornithine decarboxylase activity in blood and erythrocytes in human diseases.
Neoplasms
Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade.
Neoplasms
Polyamine metabolism and recurrence after resection for hepatocellular carcinoma.
Neoplasms
Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry.
Neoplasms
Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.
Neoplasms
Polyamine metabolism-based dual functional gene delivery system to synergistically inhibit the proliferation of cancer.
Neoplasms
Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth.
Neoplasms
Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment.
Neoplasms
Polyamine-directed preferential nutritional repletion of normal tissues in tumor-bearing hosts.
Neoplasms
Porphyrin-mediated photosensitization has a weak tumor promoting activity in mouse skin: possible role of in situ-generated reactive oxygen species.
Neoplasms
Possible mechanisms by which pro- and prebiotics influence colon carcinogenesis and tumor growth.
Neoplasms
Possible tumor-initiating and -promoting activity of p-methylcatechol and methylhydroquinone in the pyloric mucosa of rat stomach.
Neoplasms
Post-transcriptional suppression of human ornithine decarboxylase gene expression by phorbol esters in human keratinocytes.
Neoplasms
Potent suppressive activity of nonpolyphenolic fraction of green tea (Camellia sinensis) against genotoxin-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002), tumor promotor-dependent ornithine decarboxylase induction of BALB/c 3T3 fibroblast cells, and chemically induced mouse skin tumorigenesis.
Neoplasms
Potent suppressive activity of pheophytin a and b from the non-polyphenolic fraction of green tea (Camellia sinensis) against tumor promotion in mouse skin.
Neoplasms
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
Neoplasms
Preclinical renal chemo-protective potential of Prunus amygdalus Batsch seed coat via alteration of multiple molecular pathways.
Neoplasms
Preoperative values of CA 15-3 and CEA as prognostic factors in breast cancer: a multivariate analysis.
Neoplasms
Presence of a functionally altered ornithine decarboxylase activity in chrysarobin-promoted mouse epidermal papillomas.
Neoplasms
Prevention of colon cancer by pre- and probiotics: evidence from laboratory studies.
Neoplasms
Prevention of inhibitory effects of alpha-difluoromethylornithine on rat urinary bladder carcinogenesis by exogenous putrescine.
Neoplasms
Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice.
Neoplasms
Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin.
Neoplasms
Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma.
Neoplasms
Prognostic influence on survival of increased ornithine decarboxylase activity in human breast cancer.
Neoplasms
Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters.
Neoplasms
Progress in studies on the antimutagenicity and anticarcinogenicity of green tea epicatechins.
Neoplasms
Prolactin stimulation of ornithine decarboxylase activity in cultured rat mammary tumors.
Neoplasms
Promotion of skin carcinogenesis by dimethylarsinic acid in keratin (K6)/ODC transgenic mice.
Neoplasms
Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.
Neoplasms
Prostaglandins and skin tumor promotion: inhibition of tumor promoter-induced ornithine decarboxylase activity in epidermis by inhibitors of prostaglandin synthesis.
Neoplasms
Protection against 12-O-tetradecanoylphorbol-13-acetate-caused inflammation in SENCAR mouse ear skin by polyphenolic fraction isolated from green tea.
Neoplasms
Protective effect of Ocimum sanctum on 3-methylcholanthrene, 7,12-dimethylbenz(a)anthracene and aflatoxin B1 induced skin tumorigenesis in mice.
Neoplasms
Protective effect of sanguinarine on ultraviolet B-mediated damages in SKH-1 hairless mouse skin: implications for prevention of skin cancer.
Neoplasms
Protective effect of the isoflavonoid equol against hairless mouse skin carcinogenesis induced by UV radiation alone or with a chemical cocarcinogen.
Neoplasms
Protective effects of silymarin against photocarcinogenesis in a mouse skin model.
Neoplasms
Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas.
Neoplasms
Protein kinase Cdelta-mediated signal to ornithine decarboxylase induction is independent of skin tumor suppression.
Neoplasms
Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity.
Neoplasms
Quinone methide mediates in vitro induction of ornithine decarboxylase by the tumor promoter butylated hydroxytoluene hydroperoxide.
Neoplasms
Radiosynthesis and evaluation of N5-(2-18F-fluoropropanyl) ornithine as a potential agent for tumor PET imaging.
Neoplasms
Randomized phase I chemoprevention dose-seeking study of alpha-difluoromethylornithine.
Neoplasms
Rectal mucosal ornithine decarboxylase activity is not a useful marker of risk for colorectal neoplasia.
Neoplasms
Reduced expression of phospholipase C-delta, a signal-transducing enzyme, in rat colon neoplasms induced by methylazoxymethanol acetate.
Neoplasms
Refined estimates of local recurrence risks by DCIS score adjusting for clinicopathological features: a combined analysis of ECOG-ACRIN E5194 and Ontario DCIS cohort studies.
Neoplasms
Regional distribution of ornithine decarboxylase activity and polyamine levels in experimental cat brain tumors.
Neoplasms
Regulation by 1,4-diamines of the ornithine decarboxylase activity induced by ornithine in perifused tumor cells.
Neoplasms
Regulation of ornithine decarboxylase activity by corticotropin in adrenocortical tumor cell clones: roles of cyclic AMP and cyclic AMP-dependent protein kinase.
Neoplasms
Regulation of ornithine decarboxylase during cell growth. Changes in the stability and translatability of the mRNA, and in the turnover of the protein.
Neoplasms
Regulation of ornithine decarboxylase during oncogenic transformation: mechanisms and therapeutic potential.
Neoplasms
Regulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1.
Neoplasms
Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis.
Neoplasms
Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent.
Neoplasms
Regulation of ornithine decarboxylase mRNA levels in human breast cancer cells: pattern of expression and involvement of core enhancer promoter element.
Neoplasms
Regulation of polyamine biosynthesis in normal and transformed hamster cells in culture.
Neoplasms
Regulation of proliferation by fibroblast growth factor in a pancreatic cancer cell line.
Neoplasms
Relation between induction of ornithine decarboxylase and specific gene expression in rat liver in response to the tumor promoter agent clofibrate.
Neoplasms
Relation between induction of rat hepatic ornithine decarboxylase activity by tumor promoters 12-O-tetradecanoylphorbol-13-acetate and phenobarbital and levels of the polyamines putrescine, spermidine and spermine, in vivo; differential effects of retinyl-acetate.
Neoplasms
Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice.
Neoplasms
Relationship between ornithine decarboxylase levels in anaplastic gliomas and progression-free survival in patients treated with DFMO-PCV chemotherapy.
Neoplasms
Relationship of ornithine decarboxylase activity and histological findings in human hepatocellular carcinoma.
Neoplasms
Relationship of polyamine metabolism to degree of malignancy of human hepatocellular carcinoma.
Neoplasms
Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
Neoplasms
Repeated short-term stress synergizes the ROS signalling through up regulation of NFkB and iNOS expression induced due to combined exposure of trichloroethylene and UVB rays.
Neoplasms
Reporter PET Images Bortezomib Treatment-Mediated Suppression of Cancer Cell Proteasome Activity.
Neoplasms
Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice.
Neoplasms
Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase (ODC) activity by retinoids: a potential role for trans-RA-induced ZBP-89 in ODC inhibition.
Neoplasms
Retinoic acid analogues with ring modifications. Synthesis and pharmacological activity.
Neoplasms
Retinoic acid analogues. Synthesis and potential as cancer chemopreventive agents.
Neoplasms
Retinoic acid modulation of ultraviolet light-induced epidermal ornithine decarboxylase activity.
Neoplasms
Retinoids block ornithine decarboxylase induction in cells treated with the tumor promotor TPA or the peptide growth hormones, EGF and SGF.
Neoplasms
Reversal of the growth inhibitory effect of alpha-difluoromethylornithine by putrescine but not by other divalent cations.
Neoplasms
Reversible regulation of the transformed phenotype of ornithine decarboxylase- and ras-overexpressing cells by dominant-negative mutants of c-Jun.
Neoplasms
Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventive agent.
Neoplasms
Risk analysis of carcinogenesis in the remnant stomach with measurement of ornithine decarboxylase activity.
Neoplasms
Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival.
Neoplasms
Role of asbestos and active oxygen species in activation and expression of ornithine decarboxylase in hamster tracheal epithelial cells.
Neoplasms
Role of diamine oxidase during the treatment of tumour-bearing mice with combinations of polyamine anti-metabolites.
Neoplasms
Role of ornithine decarboxylase in the regulation of cell growth by IL-1 and tumor necrosis factor.
Neoplasms
Role of polyamines in mediating malignant transformation and oncogene expression.
Neoplasms
Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase.
Neoplasms
S-adenosylmethionine decarboxylase overexpression inhibits mouse skin tumor promotion.
Neoplasms
Safety and Efficacy of Laparoscopic Oophorocystectomy for Ovarian Dermoid Cyst Associated With Autoimmune Hemolytic Anemia.
Neoplasms
Saliniketals A and B, bicyclic polyketides from the marine actinomycete Salinispora arenicola.
Neoplasms
Salix caprea inhibits skin carcinogenesis in murine skin: inhibition of oxidative stress, ornithine decarboxylase activity and DNA synthesis.
Neoplasms
Selectivity of polyamine involvement in hormone action on normal and neoplastic target tissues of the rat.
Neoplasms
Selenium and difluoromethylornithine additively inhibit DMH-induced distal colon tumor formation in rats fed a fiber-free diet.
Neoplasms
Sepsis increases putrescine concentration and protein synthesis in mucosa of small intestine in rats.
Neoplasms
Short-term biomarkers of cigarette smoke condensate tumor promoting potential in mouse skin.
Neoplasms
Short-term biomarkers of tumor promotion in mouse skin treated with petroleum middle distillates.
Neoplasms
Significance of targeting polyamine metabolism as an antineoplastic strategy: unique targets for polyamine analogues.
Neoplasms
Similarity of teleocidin B and phorbol ester tumour promoters in effects on membrane receptors.
Neoplasms
Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice.
Neoplasms
Single-injection ornithine decarboxylase-directed antisense therapy using atelocollagen to suppress human cancer growth.
Neoplasms
Skin tumor promotion by argemone oil/alkaloid in mice: Evidence for enhanced cell proliferation, ornithine decarboxylase, cyclooxygenase-2 and activation of MAPK/NF-kappaB pathway.
Neoplasms
sn-1,2-Diacylglycerols mimic the effects of 12-O-tetradecanoylphorbol-13-acetate in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis.
Neoplasms
Some aspects of clearance of mitoguazone in cancer patients and experimental cancer models.
Neoplasms
Some effects of inhibitors of polyamine synthesis on experimental prostatic cancer.
Neoplasms
Sources of variability in estimating ornithine decarboxylase activity and polyamine contents in human colorectal mucosa.
Neoplasms
Specific binding, stimulation of rodent urinary bladder epithelial ornithine decarboxylase, and induction of transitional cell hyperplasia by the skin tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Neoplasms
Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis.
Neoplasms
Stable siRNA-mediated silencing of antizyme inhibitor: regulation of ornithine decarboxylase activity.
Neoplasms
Stimulating effect of excess iron feeding on spontaneous lung tumor promotion in mice.
Neoplasms
Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1.
Neoplasms
Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution.
Neoplasms
Structural requirements for novel coenzyme-substrate derivatives to inhibit intracellular ornithine decarboxylase and cell proliferation.
Neoplasms
Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases.
Neoplasms
Structure-activity relationships for epidermal ornithine decarboxylase induction and skin tumor promotion by anthrones.
Neoplasms
Studies of the mechanism by which increased spermidine/spermine N1-acetyltransferase activity increases susceptibility to skin carcinogenesis.
Neoplasms
Superinduction of mouse epidermal ornithine decarboxylase activity by repeated 12-o-tetradecanoylphorbol-13-acetate treatments.
Neoplasms
Superinduction of ornithine decarboxylase (ODC) by actinomycin D is due to stimulation of ODC mRNA translation.
Neoplasms
Supplemental calcium suppresses colonic mucosal ornithine decarboxylase activity in elderly patients with adenomatous polyps.
Neoplasms
Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice.
Neoplasms
Suppressive effects of chlorophyllin on mutagen-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002) and tumor promoter-dependent ornithine decarboxylase induction in BALB/c 3T3 fibroblast cells.
Neoplasms
Suppressive effects of the extracts of Japanese edible seaweeds on mutagen-induced umu C gene expression in Salmonella typhimurium (TA 1535/pSK 1002) and tumor promotor-dependent ornithine decarboxylase induction in BALB/c 3T3 fibroblast cells.
Neoplasms
Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
Neoplasms
Systemic alterations in ornithine decarboxylase activity caused by colon cancer in mice.
Neoplasms
Systemic inhibition of tumor promoter-induced ornithine decarboxylase in 1 alpha-hydroxyvitamin D3-treated animals.
Neoplasms
Tamarix gallica ameliorates thioacetamide-induced hepatic oxidative stress and hyperproliferative response in Wistar rats.
Neoplasms
Targeted antitumor effect induced by hTERT promoter mediated ODC antisense adenovirus.
Neoplasms
Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis.
Neoplasms
Targeting Ornithine Decarboxylase by ?-Difluoromethylornithine Inhibits Tumor Growth by Impairing Myeloid-Derived Suppressor Cells.
Neoplasms
Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma.
Neoplasms
Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.
Neoplasms
The cellular response to induction of the p21 c-Ha-ras oncoprotein includes stimulation of jun gene expression.
Neoplasms
The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.
Neoplasms
The differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the initiation-promotion protocol and by the complete carcinogenesis process.
Neoplasms
The discovery of indolone GW5074 during a comprehensive search for non-polyamine-based polyamine transport inhibitors.
Neoplasms
The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent.
Neoplasms
The effect of dietary lipid on skin tumor promotion by benzoyl peroxide: comparison of fish, coconut and corn oil.
Neoplasms
The effect of menhaden oil on choline-deficiency-induced hepatic ornithine decarboxylase activity and hepatocyte insulin receptor binding.
Neoplasms
The effects of low-energy 60-Hz environmental electromagnetic fields upon the growth-related enzyme ornithine decarboxylase.
Neoplasms
The effects of polyamine antimetabolites on polyamine-responsive casein kinase activity.
Neoplasms
The effects of serum and phorbol ester tumor promoter on ornithine decarboxylase activity in Swiss 3T3 cells.
Neoplasms
The induction of ornithine decarboxylase by phorbol 12-myristate 13-acetate or by serum is inhibited by antioxidants.
Neoplasms
The induction of ornithine decarboxylase by the tumor promoter TPA is controlled at the post-transcriptional level in murine Swiss 3T3 fibroblasts.
Neoplasms
The induction of ornithine decarboxylase by tumor promoting phorbol ester analogues in Reuber H35 hepatoma cells.
Neoplasms
The induction of ornithine decarboxylase caused by 12-O-tetradecanoylphorbol-13-acetate in isolated epidermal cells is inhibited by lipoxygenase inhibitors but not by cyclooxygenase inhibitors.
Neoplasms
The inhibition of DMBA-induced carcinogenesis by neoxanthin in hamster buccal pouch.
Neoplasms
The mechanism of skin tumor promotion caused by phorbol esters: possible involvement of arachidonic acid cascade/lipoxygenase, protein kinase C and calcium/calmodulin systems.
Neoplasms
The modulation effect of vitamin E on prostaglandin E2 level and ornithine decarboxylase activity at the promotion phase of lung tumorigenesis in mice.
Neoplasms
The morphological oncogenic signature. Reorganization of epithelial cytoarchitecture and metabolic regulation by tumor promoters and by transformation.
Neoplasms
The ornithine decarboxylase domain of the bifunctional ornithine decarboxylase/S-adenosylmethionine decarboxylase of Plasmodium falciparum: recombinant expression and catalytic properties of two different constructs.
Neoplasms
The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification.
Neoplasms
The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.
Neoplasms
The role of adenosine triphosphate, chalones, and specific proteins in controlling tumor growth fraction.
Neoplasms
The role of polyamines as a marker of tumor progression and regression in experimental tumors.
Neoplasms
The role of polyamines in human cancer: prospects for drug combination therapies.
Neoplasms
The role of prostaglandin E1 in ornithine decarboxylase induction by tumor promoters.
Neoplasms
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate induces ornithine decarboxylase in proliferating basal cells but not in differentiating cells from mouse epidermis.
Neoplasms
Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 1. Selective enzyme inhibitors.
Neoplasms
Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 2. Structural analogues and derivatives.
Neoplasms
Thymoquinone and Difluoromethylornithine (DFMO) Synergistically Induce Apoptosis of Human Acute T Lymphoblastic Leukemia Jurkat Cells Through the Modulation of Epigenetic Pathways.
Neoplasms
Time-dependent differential effects of natural and recombinant murine interferon-gamma on ornithine decarboxylase activity of tumor cells.
Neoplasms
Tip60 Protein Isoforms and Altered Function in Skin and Tumors that Overexpress Ornithine Decarboxylase.
Neoplasms
Tissue-based assay for ornithine decarboxylase to identify patients likely to respond to difluoromethylornithine.
Neoplasms
Transarterial chemoembolization with degradable starch microspheres (DSM-TACE): an alternative option for advanced HCC patients? Preliminary results.
Neoplasms
Transcription factor Sp3 antagonizes activation of the ornithine decarboxylase promoter by Sp1.
Neoplasms
Transcriptional activation of mammalian ornithine decarboxylase during stimulated growth.
Neoplasms
Transforming growth factor beta 1 selectively regulates ornithine decarboxylase gene expression in malignant H-ras transformed fibrosarcoma cell lines.
Neoplasms
Translation of ODC mRNA and polyamine transport are suppressed in ras-transformed CREF cells by depleting translation initiation factor 4E.
Neoplasms
Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis.
Neoplasms
Treatment of metastatic Lewis lung carcinoma with DL-alpha-difluoromethylornithine.
Neoplasms
Triethylenetetramine Modulates Polyamine and Energy Metabolism and Inhibits Cancer Cell Proliferation.
Neoplasms
Tumor angiogenesis and polyamines: alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in ovo and the proliferation of vascular endothelial cells in vitro.
Neoplasms
Tumor cytokinetic response to total parenteral nutrition in patients with head and neck cancers.
Neoplasms
Tumor necrosis factor stimulates ornithine decarboxylase activity in human fibroblasts and tumor target cells.
Neoplasms
Tumor progression is accompanied by significant changes in the levels of expression of polyamine metabolism regulatory genes and clusterin (sulfated glycoprotein 2) in human prostate cancer specimens.
Neoplasms
Tumor promoter-induced ornithine decarboxylase gene expression occurs independently of AP-1 activation.
Neoplasms
Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis.
Neoplasms
Tumor promoting phorbol-ester derivatives increase ornithine decarboxylase activity and polyamine biosynthesis in the liver of the rat and mouse.
Neoplasms
Tumor Promotion and Oxidative Stress in Ferric Nitrilotriacetate-Mediated Renal Carcinogenesis: Protection by Adhatoda vasica.
Neoplasms
Tumor promotion and the induction of epidermal ornithine decarboxylase activity in mechanically stimulated mouse skin.
Neoplasms
Tumor selective enhancement of radioactivity uptake in mice treated with alpha-difluoromethylornithine prior to administration of 14C-putrescine.
Neoplasms
Tumor uptake studies of D,L-[5-14C]ornithine and D,L-2-difluoromethyl [5-14C]ornithine.
Neoplasms
Tumor-derived components were responsible for suppression of ornithine decarboxylase activity in the rat wounded skin.
Neoplasms
Tumour effect on arginine/ornithine metabolic relationship in hypertrophic mouse kidney.
Neoplasms
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines.
Neoplasms
Tumourigenicity, cell-surface glycoprotein changes and ornithine decarboxylase gene pattern in Ehrlich ascites-carcinoma cells.
Neoplasms
Two chromosomal locations for human ornithine decarboxylase gene sequences and elevated expression in colorectal neoplasia.
Neoplasms
Use of a modified ornithine decarboxylase promoter to achieve efficient c-MYC- or N-MYC-regulated protein expression.
Neoplasms
Use of in vitro assays to predict the efficacy of chemopreventive agents in whole animals.
Neoplasms
Variants downstream of the ornithine decarboxylase gene influence risk of colorectal adenoma and aspirin chemoprevention.
Neoplasms
Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5'-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma.
Neoplasms
Virtual screening of natural inhibitors targeting ornithine decarboxylase with pharmacophore scaffolding of DFMO and validation by molecular dynamics simulation studies.
Neoplasms
Volatile Composition and Biological Activities of the Leaf Essential Oil from Zanthoxylum limoncello Grown in Oaxaca, México.
Neoplasms
Wedelolactone mitigates UVB induced oxidative stress, inflammation and early tumor promotion events in murine skin: plausible role of NFkB pathway.
Neoplasms
Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B.
Neoplasms
[A ornithine decarboxylase activity and proliferating cell nuclear antigen in gastric cancer]
Neoplasms
[A study of ornithine decarboxylase activity in tumor tissue and rectal mucosa in patients with colorectal cancer or adenoma]
Neoplasms
[Antitumor effect of alpha-difluoromethylornithine (DFMO) changes in ornithine decarboxylase (ODC) activity and polyamine (PA) levels in human tumor transplanted into nude mice]
Neoplasms
[Epigenetic mechanism of tumor promotion. Interrelationship between inflammation and ornithine decarboxylase activity induced in vitro by the carcinogenic 12-O-tetradecanoyl-phorbol-13-acetate]
Neoplasms
[Gene expression profiling of human ovarian epithelial tumors by digo nucleotide microarray]
Neoplasms
[Identification of novel molecules regulating differentiation and hormone secretion and clarification of their functional mechanisms in pancreatic endocrine cells]
Neoplasms
[Increased ornithine decarboxylase activity is not essential for progesterone-induced Bufo oocyte maturation]
Neoplasms
[Inhibition of ornithine decarboxylase activity and epidermal papilloma in mice by beta-carotene]
Neoplasms
[Inhibition of the growth of a murine transplantable tumor, colon 26, by the prostaglandin synthetase inhibitor, indomethacin]
Neoplasms
[Inhibitory effects of OK-432 administered orally on colon carcinoma induced by DMH in rats]
Neoplasms
[Optimization of a cucurbit[6]uril-based real-time label-free method for analyzing the activity of ornithine decarboxylase].
Neoplasms
[Ornithine decarboxylase (ODC) activity in the mucosa of human remnant stomach, and the clinical significance on tumor promotion]
Neoplasms
[Ornithine decarboxylase activity and polyamine content in human adenocarcinomas of the stomach and large intestine]
Neoplasms
[Ornithine decarboxylase activity and polyamine levels in human thyroid tumor tissue]
Neoplasms
[Regulation of tumor promotion by 1 alpha, 25-dihydroxyvitamin D3, an active form of vitamin D3]
Neoplasms
[Reversion of malignant phenotypes of human lung squamous carcinoma cells by ornithine decarboxylase antisense RNA]
Neoplasms
[The actions of TPA-type as well as non-TPA type tumor promoters and their mechanism(s) in tumor promotion]
Neoplasms
[The study of polyamine levels and enzyme activities in metabolic pathway of polyamine in spleen of mice inoculated tumor cells]
Neoplasms
[Therapy of prostate carcinoma with polyamine synthesis inhibitors. I. Physiological and pathophysiological principles]
Neoplasms, Basal Cell
Significance of arginase and ornithine in malignant tumors of the human skin.
Neoplasms, Squamous Cell
Ornithine decarboxylase inhibition downregulates multiple pathways involved in the formation of precancerous lesions of esophageal squamous cell cancer.
Neoplasms, Squamous Cell
Significance of arginase and ornithine in malignant tumors of the human skin.
Nephritis
Inhibition of Inducible Nitric Oxide Synthase Alters Thy-1 Glomeruonephritis in Rats.
Neural Tube Defects
The superposition of a temporally incoherent magnetic field inhibits 60 Hz-induced changes in the ODC activity of developing chick embryos.
Neuroblastoma
A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma.
Neuroblastoma
A human neuroblastoma cell line with a stable ornithine decarboxylase in vivo and in vitro.
Neuroblastoma
Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells.
Neuroblastoma
Amplification of N-myc and ornithine decarboxylase genes in human neuroblastoma and hydroxyurea-resistant hamster cell lines.
Neuroblastoma
AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.
Neuroblastoma
Antiproliferative effects of inhibitors of polyamine synthesis in tumors of neural origin.
Neuroblastoma
Antitumor effects of vitamin A and inhibitors of ornithine decarboxylase in cultured neuroblastoma and glioma cells.
Neuroblastoma
Asparagine markedly induces the expression of ornithine decarboxylase gene in transformed mammalian cells but not in their untransformed counterparts.
Neuroblastoma
Changes in inducibility of ornithine decarboxylase activity in differentiating human neuroblastoma cells.
Neuroblastoma
Changes of ornithine decarboxylase activity and polyamine content upon differentiation of mouse NB-15 neuroblastoma cells.
Neuroblastoma
Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells.
Neuroblastoma
Cyclic AMP-mediated induction of ornithine decarboxylase of glioma and neuroblastoma cells.
Neuroblastoma
Cytotoxic activity of difluoromethylornithine compared with fenretinide in neuroblastoma cell lines.
Neuroblastoma
Differences in the mode of regulation of ornithine decarboxylase activity in undifferentiated versus differentiated mouse N-18 neuroblastoma cells.
Neuroblastoma
Differentiation of a mouse neuroblastoma variant cell line whose ornithine decarboxylase gene has been amplified.
Neuroblastoma
Effect of GABA and isogabaculine on ornithine decarboxylase and putrescine metabolism.
Neuroblastoma
Effects of exposure to DAMPS and GSM signals on Ornithine Decarboxylase (ODC) activity: II- SH-SY5Y human neuroblastoma cells.
Neuroblastoma
Effects of inhibitors of ornithine decarboxylase on the differentiation of mouse neuroblastoma cells.
Neuroblastoma
Enzyme regulation in neuroblastoma cells in a salts/glucose medium: induction of ornithine decarboxylase by asparagine and glutamine.
Neuroblastoma
Human ornithine decarboxylase sequences map to chromosome regions 2pter----p23 and 7cen----qter but are not coamplified with the NMYC oncogene.
Neuroblastoma
Induction of a protein inhibitor to ornithine decarboxylase by the end products of its reaction.
Neuroblastoma
Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma.
Neuroblastoma
Investigation of co-amplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a DEAD box gene, DDX1, with N-myc in neuroblastoma. United Kingdom Children's Cancer Study Group.
Neuroblastoma
Mechanism of regulation of ornithine decarboxylase gene expression by asparagine in a variant mouse neuroblastoma cell line.
Neuroblastoma
Microarray analysis supports a role for ccaat/enhancer-binding protein-beta in brain injury.
Neuroblastoma
Mitogenic response of human SH-SY5Y neuroblastoma cells to insulin-like growth factor I and II is dependent on the stage of differentiation.
Neuroblastoma
Morphine inhibits cyclic AMP-dependent protein kinase and ornithine decarboxylase activities in neuroblastoma X glioma hybrid cells.
Neuroblastoma
Novel Interaction of Ornithine Decarboxylase with Sepiapterin Reductase Regulates Neuroblastoma Cell Proliferation.
Neuroblastoma
Opiates and cultured neuroblastoma x glioma cells. Effect on cyclic AMP and polyamine levels and on ornithine decarboxylase and protein kinase activities.
Neuroblastoma
Ornithine decarboxylase activity and the growth of neuroblastoma cells. The effects of bromoacetylcholine, bromoacetate and 1,3-diaminopropane.
Neuroblastoma
Ornithine decarboxylase inhibition by alpha-difluoromethylornithine activates opposing signaling pathways via phosphorylation of both Akt/protein kinase B and p27Kip1 in neuroblastoma.
Neuroblastoma
Six loci mapped on to human chromosome 2p are assigned to sheep chromosome 3p.
Neuroblastoma
Studies on the role of protein synthesis and of sodium on the regulation of ornithine decarboxylase activity.
Neuroblastoma
Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
Neuroblastoma
Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma.
Neuroblastoma
Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma.
Neuroblastoma
The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification.
Neuroblastoma
Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11.
Neuroendocrine Tumors
Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer.
Non-alcoholic Fatty Liver Disease
Peculiarity of prooxidant-antioxidant balance indicators in patients with nonalcoholic fatty liver disease who have been exposed to ionizing radiation due to the Chornobyl NPP accident.
Opportunistic Infections
Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-alpha-difluoromethylornithine.
Optic Nerve Hypoplasia
Optic Disc Coloboma in children - prevalence, clinical characteristics and associated morbidity.
ornithine decarboxylase deficiency
Deficiency of ovarian ornithine decarboxylase contributes to aging-related egg aneuploidy in mice.
ornithine decarboxylase deficiency
Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury.
Osteoblastoma
Enhancement of ornithine decarboxylase and Na+, K+ ATPase in osteoblastoma cells by intermittent compression.
Osteosarcoma
Effects of parathyroid hormone on ornithine decarboxylase activity in human osteosarcoma cells.
Osteosarcoma
Identification of chemoradiation-resistant osteosarcoma stem cells using an imaging system for proteasome activity.
Osteosarcoma
Inhibition of osteoblastic cell proliferation and ornithine decarboxylase activity by ethanol.
Osteosarcoma
Involvement of cAMP and calcium in the induction of ornithine decarboxylase activity in an osteoblast cell line.
Otitis
Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
Ovarian Neoplasms
Treatment with inhibitors of polyamine biosynthesis, which selectively lower intracellular spermine, does not affect the activity of alkylating agents but antagonizes the cytotoxicity of DNA topoisomerase II inhibitors.
Ovarian Neoplasms
[pemetrexed + sildenafil], via autophagy-dependent HDAC down-regulation, enhances the immunotherapy response of NSCLC cells.
Pancreatic Neoplasms
Effects of cyclosporin A and alpha-difluoromethylornithine on the growth of hamster pancreatic cancer in vitro.
Pancreatic Neoplasms
Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.
Pancreatic Neoplasms
Inhibition of growth of human or hamster pancreatic cancer cell lines by alpha-difluoromethylornithine alone and combined with cis-diamminedichloroplatinum(II).
Pancreatic Neoplasms
Inhibitory effects of a calcium antagonist on ornithine decarboxylase induction in pancreatic cancer cell lines.
Pancreatic Neoplasms
Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer.
Pancreatic Neoplasms
Multi-omics analysis reveals that ornithine decarboxylase contributes to erlotinib resistance in pancreatic cancer cells.
Pancreatic Neoplasms
Ornithine decarboxylase enzyme activity in human and hamster pancreatic tumor cell lines.
Pancreatitis
Effect of inorganic ions on the oxyhemoglobin dissociation curve of severely ill patients.
Pancreatitis
Increases in Ki-ras and ornithine decarboxylase gene expression in rat pancreas after caerulein-induced pancreatitis.
Papilloma
A role for protein kinase C-delta in the regulation of ornithine decarboxylase expression by oxidative stress.
Papilloma
Activation of mouse epidermal tumor ornithine decarboxylase by GTP: evidence for different catalytic forms of the enzyme.
Papilloma
Biochemical characteristics and differentiating activity of 4-oxo analogs of retinoic acid.
Papilloma
Calyculin A, an inhibitor of protein phosphatases, a potent tumor promoter on CD-1 mouse skin.
Papilloma
Chemopreventive effects of alpha-santalol on skin tumor development in CD-1 and SENCAR mice.
Papilloma
Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin.
Papilloma
Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas.
Papilloma
Conversion of C57Bl/6 mice from a tumor promotion-resistant to a -sensitive phenotype by enhanced ornithine decarboxylase expression.
Papilloma
Effects of dose and duration of treatment with the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate on mouse skin carcinogenesis.
Papilloma
Effects of the antiandrogen, cyproterone acetate, on the induction of papillomas, DNA synthesis and ornithine decarboxylase activity in mouse skin.
Papilloma
Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene.
Papilloma
Epidermal ornithine decarboxylase induction and mouse skin tumor promotion by quinones.
Papilloma
Expression and localization of ornithine decarboxylase in reversible papillomatosis induced by uracil in rat bladder.
Papilloma
Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors.
Papilloma
Identification of epidermal cell subpopulations with increased ornithine decarboxylase activity following treatment of murine epidermis with 12-O-tetradecanoylphorbol-13-acetate.
Papilloma
Inhibition of mouse skin tumor promotion and of promoter-induced epidermal polyamine biosynthesis by methylglyoxal bis(butylamidinohydrazone).
Papilloma
Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine.
Papilloma
Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion.
Papilloma
Inhibitory effects of the standardized extract (DA-9601) of Artemisia asiatica Nakai on phorbol ester-induced ornithine decarboxylase activity, papilloma formation, cyclooxygenase-2 expression, inducible nitric oxide synthase expression and nuclear transcription factor kappa B activation in mouse skin.
Papilloma
Modulation of the co-promoting activity of gamma interferon in SENCAR and C57BL/6 mouse skin by difluoromethylornithine and the scheduling and duration of interferon treatment.
Papilloma
Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
Papilloma
Ornithine decarboxylase from mouse epidermis and epidermal papillomas: differences in enzymatic properties and structure.
Papilloma
Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation.
Papilloma
Presence of a functionally altered ornithine decarboxylase activity in chrysarobin-promoted mouse epidermal papillomas.
Papilloma
Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis.
Papilloma
Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and -epsilon transgenic mice.
Papilloma
Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase (ODC) activity by retinoids: a potential role for trans-RA-induced ZBP-89 in ODC inhibition.
Papilloma
Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase.
Papilloma
Spermidine/spermine N1-acetyltransferase, a new biochemical marker for epithelial proliferation in rat bladder.
Papilloma
Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B.
Papilloma
[Inhibition of ornithine decarboxylase activity and epidermal papilloma in mice by beta-carotene]
Papilloma
[Study on the anti-carcinogenic effects of three compounds in Kaempferia galanga L]
Parasitemia
A Trypanosoma brucei bloodstream form mutant deficient in ornithine decarboxylase can protect against wild-type infection in mice.
Parasitemia
Plasmodium AdoMetDC/ODC bifunctional enzyme is essential for male sexual stage development and mosquito transmission.
Parasitic Diseases
In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase.
Parasitic Diseases
The ornithine decarboxylase domain of the bifunctional ornithine decarboxylase/S-adenosylmethionine decarboxylase of Plasmodium falciparum: recombinant expression and catalytic properties of two different constructs.
Peritonitis
ODC (Ornithine Decarboxylase)-Dependent Putrescine Synthesis Maintains MerTK (MER Tyrosine-Protein Kinase) Expression to Drive Resolution.
Pheochromocytoma
Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists.
Pheochromocytoma
Correlation between lead-induced changes in cerebral ornithine decarboxylase and protein kinase C activities during development and in cultured PC 12 cells.
Pheochromocytoma
Induction of ornithine decarboxylase by nerve growth factor in PC12 cells: dissection by purine analogues.
Pheochromocytoma
Nerve growth factor rapidly induces ornithine decarboxylase mRNA in PC12 rat pheochromocytoma cells.
Pheochromocytoma
Nerve growth factor-mediated selective induction of ornithine decarboxylase in rat pheochromocytoma; a cyclic AMP-independent process.
Pheochromocytoma
The induction of ornithine decarboxylase by nerve growth factor and epidermal growth factor in PC12 cells.
Photosensitivity Disorders
Porphyrin-mediated photosensitization has a weak tumor promoting activity in mouse skin: possible role of in situ-generated reactive oxygen species.
Pituitary Neoplasms
Activity of ornithine decarboxylase (ODC) and polyamine levels as biochemical markers of malignancy in human brain tumors.
Plant Diseases
Polyamine metabolism during the germination of Sclerotinia sclerotiorum ascospores and its relation with host infection.
Plant Diseases
Prevention of a plant disease by specific inhibition of fungal polyamine biosynthesis.
Pneumonia
Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-alpha-difluoromethylornithine.
Pneumonia, Pneumocystis
High-pressure liquid chromatographic analysis of eflornithine in serum.
Pneumonia, Pneumocystis
Mechanism and Tissue Specificity of Nicotine-mediated Lung S-Adenosylmethionine Reduction.
Pneumonia, Pneumocystis
Ornithine decarboxylase in Pneumocystis carinii and implications for therapy.
Pneumonia, Pneumocystis
Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-alpha-difluoromethylornithine.
Polycythemia Vera
Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia.
Potassium Deficiency
Effects of potassium deficiency on potassium, polyamines and amino acids in mouse tissues.
Potassium Deficiency
Hypokalemia decreases testosterone production in male mice by altering luteinizing hormone secretion.
Potassium Deficiency
Potassium regulates plasma testosterone and renal ornithine decarboxylase in mice.
Precancerous Conditions
Individual variability of pathological parameters in chemically induced rat colon tumors.
Priapism
The mechanism of opiorphin-induced experimental priapism in rats involves activation of the polyamine synthetic pathway.
Progeria
Changes of serum-induced ornithine decarboxylase activity and putrescine content during aging of IMR-90 human diploid fibroblasts.
Prostatic Hyperplasia
Ornithine Decarboxylase (ODC) Expression Pattern in Human Prostate Tissues and ODC Transgenic Mice.
Prostatic Hyperplasia
Ornithine decarboxylase activity and its gene expression are increased in benign hyperplastic prostate.
Prostatic Hyperplasia
Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans.
Prostatic Neoplasms
Activation of polyamine catabolic enzymes involved in diverse responses against epibrassinolide-induced apoptosis in LNCaP and DU145 prostate cancer cell lines.
Prostatic Neoplasms
Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer.
Prostatic Neoplasms
Androgen regulation of the human ornithine decarboxylase promoter in prostate cancer cells.
Prostatic Neoplasms
Antitumor effect of antisense ODC adenovirus on human prostate cancer cells.
Prostatic Neoplasms
Association among an ornithine decarboxylase polymorphism, androgen receptor gene (CAG) repeat length and prostate cancer risk.
Prostatic Neoplasms
Chemoprevention of prostate cancer with the polyamine synthesis inhibitor difluoromethylornithine.
Prostatic Neoplasms
Chemoprevention of prostate carcinogenesis by alpha-difluoromethylornithine in TRAMP mice.
Prostatic Neoplasms
Differences in ornithine decarboxylase and androgen receptor allele frequencies among ethnic groups.
Prostatic Neoplasms
Effect of parathyroid hormone related protein, and dihydrotestosterone on proliferation and ornithine decarboxylase mRNA in human prostate cancer cell lines.
Prostatic Neoplasms
Effects of antisense RNA targeting of ODC and AdoMetDC on the synthesis of polyamine synthesis and cell growth in prostate cancer cells using a prostatic androgen-dependent promoter in adenovirus.
Prostatic Neoplasms
Fibroblast growth factor and ornithine decarboxylase 5'UTRs enable preferential expression in human prostate cancer cells and in prostate tumors of PTEN(-/-) transgenic mice.
Prostatic Neoplasms
Ornithine Decarboxylase (ODC) Expression Pattern in Human Prostate Tissues and ODC Transgenic Mice.
Prostatic Neoplasms
Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans.
Prostatic Neoplasms
Potentiation of methylglyoxal-bis-guanylhydrazone by alpha-difluoromethylornithine in rat prostate cancer.
Prostatic Neoplasms
Prostate cancer chemoprevention by green tea: in vitro and in vivo inhibition of testosterone-mediated induction of ornithine decarboxylase.
Prostatic Neoplasms
Reduction of oxidative stress and ornithine decarboxylase expression in a human prostate cancer cell line PC-3 by a combined treatment with ?-tocopherol and naringenin.
Prostatic Neoplasms
Some aspects of clearance of mitoguazone in cancer patients and experimental cancer models.
Prostatic Neoplasms
Some effects of inhibitors of polyamine synthesis on experimental prostatic cancer.
Prostatic Neoplasms
Targeted antitumor effect induced by hTERT promoter mediated ODC antisense adenovirus.
Prostatitis
The effect of alpha-difluromethylornithine and tartaric acid on sperm count, seminal gamma GT, FSH, LH, testosterone and steroid excretion in patients with chronic prostatitis.
Protein Deficiency
Maternal dietary protein deficiency decreases nitric oxide synthase and ornithine decarboxylase activities in placenta and endometrium of pigs during early gestation.
Pseudorabies
Lytic infection of pseudorabies virus in the presence of spermine, spermidine, or DFMO.
Psoriasis
Effects of sphingosine, isoquinoline and tannic acid on the human tape-stripping model and the psoriatic lesion.
Psoriasis
Magnitude of ornithine decarboxylase induction by epidermal mitogens: effect of the assay technique.
Psoriasis
The induction of epidermal ornithine decarboxylase following tape stripping is inhibited by a topical vitamin D3 analogue (MC903).
Psoriasis
[The ornithine decarboxylase activity of the epidermis in psoriasis as a biochemical index of the hyperproliferative process]
Puberty, Delayed
Alpha-difluoromethylornithine modifies FSH secretion and puberty onset in the female rat.
Puberty, Delayed
alpha-difluoromethylornithine modifies gonadotropin-releasing hormone release and follicle-stimulating hormone secretion in the immature female rat.
Pulmonary Edema
Monokine-induced lung injury in rats: similarities to monocrotaline-induced pneumotoxicity.
Rectal Neoplasms
[A study of ornithine decarboxylase activity in tumor tissue and rectal mucosa in patients with colorectal cancer or adenoma]
Renal Insufficiency
Messenger RNA for enzymes of ornithine and polyamine metabolism are selectively underexpressed in kidney of 5/6 nephrectomized rats.
Reperfusion Injury
Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage.
Reperfusion Injury
Ornithine decarboxylase activity in cerebral post-ischemic reperfusion damage: effect of methionine sulfoximine.
Reperfusion Injury
Role of ornithine decarboxylase/polyamine pathway in focal cerebral ischemia-reperfusion injury and its mechanism in rats.
Respiratory Distress Syndrome
Effect of inorganic ions on the oxyhemoglobin dissociation curve of severely ill patients.
Respiratory Distress Syndrome
Inhibition of ornithine decarboxylase restores hypoxic pulmonary vasoconstriction in endotoxemic mice.
Respiratory Distress Syndrome
Right shift of the oxyhemoglobin dissociation curve in acute respiratory distress syndrome.
Respiratory Insufficiency
[The use of the Siggaard-Andersen model of the oxyhemoglobin dissociation curve in patients in the immediate period following open heart surgery]
Retinal Perforations
Internal limiting membrane graft as a treatment for the retinal detachment secondary to an optic disc coloboma.
Retinoblastoma
Effect of elevated levels of ornithine decarboxylase on cell cycle progression in skin.
Retinoblastoma
Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma.
Retinoblastoma
Lipid peroxide-induced redox imbalance differentially mediates CaCo-2 cell proliferation and growth arrest.
Retinoblastoma
Polyamine depletion induces G1 and S phase arrest in human retinoblastoma Y79 cells.
Retinoblastoma
Structure based design of inhibitory peptides targeting ornithine decarboxylase dimeric interface and in vitro validation in human retinoblastoma Y79 cells.
Retinoblastoma
Transcriptional regulation of the ornithine decarboxylase gene by c-Myc/Max/Mad network and retinoblastoma protein interacting with c-Myc.
Rhabdomyosarcoma
Single-injection ornithine decarboxylase-directed antisense therapy using atelocollagen to suppress human cancer growth.
Root Resorption
Differentiation and functions of osteoclasts and odontoclasts in mineralized tissue resorption.
Sarcoma
Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines.
Sarcoma
Interferon-gamma inhibits cell replication, but not pp60src activity of RSV-transformed fibroblasts.
Sarcoma
Ornithine decarboxylase activity in cells acutely and chronically transformed by murine sarcoma virus.
Sarcoma 180
[Effects of diamines and their derivatives on ornithine decarboxylase activity in mouse sarcoma 180 in vivo]
Sarcoma, Avian
Ornithine decarboxylase induction during B1 progression of normal and Rous sarcoma virus-transformed cells.
Sarcoma, Avian
Polyamine metabolism in normal and in virus-transformed chick embryo fibroblasts.
Sarcoma, Avian
Polyamines are essential for cell transformation by pp60v-src: delineation of molecular events relevant for the transformed phenotype.
Sarcoma, Yoshida
Tumor-derived components were responsible for suppression of ornithine decarboxylase activity in the rat wounded skin.
Sciatic Neuropathy
Changes of ornithine decarboxylase activity in dorsal root ganglion cells after axon injury: possible relationship to alterations in neuronal chromatin.
Scleroderma, Systemic
Elevated expression of epidermal ornithine decarboxylase mRNA in scleroderma.
Seizures
Changes in polyamine levels and spectrin degradation following kainate-induced seizure activity: effect of difluoromethylornithine.
Seizures
Cyclooxygenase-2 induction in cerebral cortex: an intracellular response to synaptic excitation.
Seizures
Induction of immediate early genes, interleukin-1 beta and ornithine decarboxylase messenger RNA in spinal cord by seizures.
Seizures
Induction of ornithine decarboxylase as a possible mediator of seizure-elicited changes in genomic expression in rat hippocampus.
Seizures
Induction of ornithine decarboxylase by subseizure stimulation in the hippocampus in vivo.
Seizures
Ornithine decarboxylase induction and polyamine synthesis in the kindling of seizures: the effect of alpha-difluoromethylornithine.
Seizures
Regional variation in the response of cerebral ornithine decarboxylase to electroconvulsive shock.
Seizures
Seizure activity-induced changes in polyamine metabolism and neuronal pathology during the postnatal period in rat brain.
Seizures
The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems.
Seizures
Transcription-dependent and -independent induction of cerebral ornithine decarboxylase.
Seizures
Transcriptional activation of ornithine decarboxylase in adult and neonatal hippocampal slices.
Sepsis
Influence of sepsis and endotoxemia on polyamine metabolism in mucosa of small intestine in rats.
Sepsis
Sepsis increases putrescine concentration and protein synthesis in mucosa of small intestine in rats.
Sepsis
Sepsis stimulates polyamine biosynthesis in the liver and increases tissue levels of ornithine decarboxylase mRNA.
Shock, Septic
Effect of inorganic ions on the oxyhemoglobin dissociation curve of severely ill patients.
Short Bowel Syndrome
Intestinal ornithine decarboxylase in short bowel syndrome patients with oral diet.
Skin Diseases
A novel synthetic vitamin-A-like compound (a polyprenoic acid derivative: E-5166) inhibits UVB-stimulated epidermal ornithine decarboxylase activity.
Skin Neoplasms
A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development.
Skin Neoplasms
Chemopreventive effects of alpha-santalol on skin tumor development in CD-1 and SENCAR mice.
Skin Neoplasms
Chemopreventive effects of pomegranate seed oil on skin tumor development in CD1 mice.
Skin Neoplasms
Chemopreventive effects of various concentrations of alpha-santalol on skin cancer development in CD-1 mice.
Skin Neoplasms
Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model.
Skin Neoplasms
Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC.
Skin Neoplasms
Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine.
Skin Neoplasms
Investigating Ornithine Decarboxylase Posttranscriptional Regulation Via a Pulldown Assay Using Biotinylated Transcripts.
Skin Neoplasms
Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor.
Skin Neoplasms
Targeting ornithine decarboxylase for the prevention of nonmelanoma skin cancer in humans.
Sleep Apnea, Obstructive
Stability of oxyhemoglobin affinity in patients with obstructive sleep apnea-hypopnea syndrome without daytime hypoxemia.
Small Cell Lung Carcinoma
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
Spinal Cord Compression
Changes in ornithine decarboxylase activity and putrescine concentrations after spinal cord compression injury in the rat.
Squamous Cell Carcinoma of Head and Neck
Inhibition effect of miR-150 on the progression of oral squamous cell carcinoma by data analysis model based on independent sample T-test.
Squamous Cell Carcinoma of Head and Neck
Modulation of L-Arginine-Arginase Metabolic Pathway Enzymes: Immunocytochemistry and mRNA Expression in Peripheral Blood and Tissue Levels in Head and Neck Squamous Cell Carcinomas in North East India.
Squamous Cell Carcinoma of Head and Neck
Ornithine decarboxylase activity in tumor and normal tissue of head and neck cancer patients.
Starvation
Characterization of the Link between Ornithine, Arginine, Polyamine and Siderophore Metabolism in Aspergillus fumigatus.
Starvation
Correlation between circadian rhythms of polyamine synthesis and cell proliferation in rat liver.
Starvation
Deprivation of a single amino acid induces protein synthesis-dependent increases in c-jun, c-myc, and ornithine decarboxylase mRNAs in Chinese hamster ovary cells.
Starvation
Effect of starvation and refeeding on polyamine concentrations and ornithine decarboxylase antizyme in mammary gland of lactating rats.
Starvation
Effects of starvation and difluoromethylornithine (DFMO) on diamine oxidase activity in rat ileum.
Starvation
Enzyme induction in a temperature-sensitive cell cycle mutant of Chinese hamster fibroblasts.
Starvation
Factors regulating the induction of ornithine decarboxylase in fetal rat liver cells in culture.
Starvation
Identification of low-dose multidrug combinations for sunitinib-naive and pre-treated renal cell carcinoma.
Starvation
Induction of ornithine decarboxylase in colon and liver by starvation and refeeding: a comparison of effects on total and holoenzyme.
Starvation
Modifications in ornithine decarboxylase and diamine oxidase in small bowel mucosa of starved and refed rats.
Starvation
Ornithine decarboxylase activity and cell cycle regulation in Saccharomyces cerevisiae.
Starvation
Ornithine decarboxylase activity in mouse tumour tissue in response to refeeding and diet components.
Starvation
Ornithine decarboxylase gene of Neurospora crassa: isolation, sequence, and polyamine-mediated regulation of its mRNA.
Starvation
Ornithine decarboxylase induction in rat colon: synergistic effects of intrarectal instillation of sodium deoxycholate and starvation-refeeding.
Starvation
Polyamine dependence of Chinese hamster ovary cells in serum-free culture is due to deficient arginase activity.
Starvation
Polyamine depletion inhibits the autophagic response modulating Trypanosoma cruzi infectivity.
Starvation
Polyamine starvation prolongs the S and G2 phases of polyamine-dependent (arginase-deficient) CHO cells.
Starvation
Polyamines, NO and cGMP mediate stimulation of DNA synthesis by tumor necrosis factor and lipopolysaccharide in chick embryo cardiomyocytes.
Starvation
Regulation of ornithine decarboxylase in skeletal muscle: evidence for the involvement of an insulin-dependent serum factor.
Starvation
Regulation of the activity of ornithine decarboxylase and S-adenosylmethionine decarboxylase in mammary gland and liver of lactating rats. Effects of starvation, prolactin and insulin deficiency.
Starvation
Substrate specificity in the stimulation of intestinal ornithine decarboxylase activity by refeeding after starvation.
Stomach Diseases
Helicobacter pylori CagA induces ornithine decarboxylase upregulation via Src/MEK/ERK/c-Myc pathway: implication for progression of gastric diseases.
Stomach Neoplasms
?-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY.
Stomach Neoplasms
A mechanistic study of cigarette smoke and cyclooxygenase-2 on proliferation of gastric cancer cells.
Stomach Neoplasms
Alpha1-adrenoceptor stimulation enhances experimental gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Stomach Neoplasms
Attenuating effect of ornithine decarboxylase inhibitor (1,3-diaminopropane) on bombesin enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.
Stomach Neoplasms
Attenuation by d-limonene of sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Stomach Neoplasms
Decrease in ornithine decarboxylase activity after eradication of Helicobacter pylori.
Stomach Neoplasms
Determination of binding constant of transcription factor myc-max/max-max and E-box DNA: the effect of inhibitors on the binding.
Stomach Neoplasms
Dietary supplementation with carbonate increases expression of ornithine decarboxylase and proliferation in gastric mucosa in a rat model of gastric cancer.
Stomach Neoplasms
Downregulation of ornithine decarboxylase by pcDNA-ODCr inhibits gastric cancer cell growth in vitro.
Stomach Neoplasms
Effect of beta-carotene supplementation on the activity of ornithine decarboxylase (ODC) in stomach mucosa of patients with chronic atrophic gastritis.
Stomach Neoplasms
Effect of ornithine decarboxylase inhibitor on tetragastrin treatment of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Stomach Neoplasms
Effect of remedies for enhancing resistance and relieving blood stasis on metastasis in postoperative gastric cancer and ornithine decarboxylase levels.
Stomach Neoplasms
Expression of ornithine decarboxylase in precancerous and cancerous gastric lesions.
Stomach Neoplasms
Gene polymorphisms in the ornithine decarboxylase-polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations.
Stomach Neoplasms
Helicobacter pylori CagA induces ornithine decarboxylase upregulation via Src/MEK/ERK/c-Myc pathway: implication for progression of gastric diseases.
Stomach Neoplasms
Increased mucosal ornithine decarboxylase activity in human gastric cancer.
Stomach Neoplasms
Indomethacin interferes with EGF-induced activation of ornithine decarboxylase in gastric cancer cells.
Stomach Neoplasms
Low-protein diet promotes sodium chloride-enhanced gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Stomach Neoplasms
Ornithine decarboxylase (ODC1) gene variant (rs2302615) is associated with gastric cancer independently of Helicobacter pylori CagA serostatus.
Stomach Neoplasms
Ornithine decarboxylase inhibitor attenuates NaCl enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.
Stomach Neoplasms
Ornithine decarboxylase inhibitor lessens the rat gastric carcinogenesis enhancement caused by tyrosine methyl ester.
Stomach Neoplasms
Risk analysis of carcinogenesis in the remnant stomach with measurement of ornithine decarboxylase activity.
Stomach Neoplasms
Severe atrophic gastritis with extreme hypergastrinemia and gene expression of ornithine decarboxylase (ODC) and cyclo-oxygenase-2 (COX-2) expression: comparison with gastric cancer.
Stomach Neoplasms
Synergistic antiproliferative activity of human fibroblast interferon in combination with alpha-difluoromethylornithine against human gastric cancer cells in vitro.
Stomach Neoplasms
Unsaturated fatty acids bind Myc-Max transcription factor and inhibit Myc-Max-DNA complex formation.
Stomach Neoplasms
[A ornithine decarboxylase activity and proliferating cell nuclear antigen in gastric cancer]
Stomach Neoplasms
[Protective effect of diallyl sulfide, a natural extract of garlic, on MNNG-induced damage of rat glandular stomach mucosa]
Stomach Neoplasms
[The ornithine decarboxylase activity of the gastric remnant mucosa: the effect of the duodenal juice with bile on the gastric mucosa]
Stomach Ulcer
Cigarette smoke extracts delay wound healing in the stomach: involvement of polyamine synthesis.
Stomach Ulcer
Increase in apoptosis and decrease in ornithine decarboxylase activity of the gastric mucosa in patients with atrophic gastritis and gastric ulcer after successful eradication of Helicobacter pylori.
Stroke
Brain Neurons Express Ornithine Decarboxylase-Activating Antizyme Inhibitor 2 with Accumulation in Alzheimer's Disease.
Stroke
Differing effects of alpha-difluoromethylornithine and CGP 40116 on polyamine levels and infarct volume in a rat model of focal cerebral ischaemia.
Stroke
Induction of ornithine decarboxylase mRNA in transient focal cerebral ischemia in the rat.
Stroke
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion.
Subacute Combined Degeneration
Subacute combined degeneration and induction of ornithine decarboxylase in spinal cords of totally gastrectomized rats.
Subacute Combined Degeneration
Subacute combined degeneration in the spinal cords of totally gastrectomized rats. Ornithine decarboxylase induction, cobalamin status, and astroglial reaction.
Sunburn
Evaluation of a topical iron chelator in animals and in human beings: short-term photoprotection by 2-furildioxime.
Sunburn
Photoprotection by honeybush extracts, hesperidin and mangiferin against UVB-induced skin damage in SKH-1 mice.
Sunburn
Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas.
Sunburn
Retinoic acid modulation of ultraviolet light-induced epidermal ornithine decarboxylase activity.
Teratocarcinoma
Increased expression of c-jun, but not retinoic acid receptor beta, is associated with F9 teratocarcinoma stem cell differentiation induced by polyamine depletion.
Teratocarcinoma
Interference with DNA methyltransferase activity and genome methylation during F9 teratocarcinoma stem cell differentiation induced by polyamine depletion.
Teratocarcinoma
Polyamine depletion up-regulates c-Myc expression, yet induces G(1) arrest and terminal differentiation of F9 teratocarcinoma stem cells.
Thymoma
Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC.
Tongue Neoplasms
Chemoprevention of oral carcinogenesis by DL-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor: dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats.
Toxoplasmosis
Endogenous polyamine levels in macrophages is sufficient to support growth of Toxoplasma gondii.
Trauma, Nervous System
Simultaneous assay of ornithine decarboxylase and polyamines after central nervous system injury in gerbil and rat.
Trichothiodystrophy Syndromes
A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients.
Triple Negative Breast Neoplasms
Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase.
Triple Negative Breast Neoplasms
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
Trypanosomiasis
Catalytic irreversible inhibition of Trypanosoma brucei brucei ornithine decarboxylase by substrate and product analogs and their effects on murine trypanosomiasis.
Trypanosomiasis
Difluoromethylornithine for arseno-resistant Trypanosoma brucei gambiense sleeping sickness.
Trypanosomiasis
Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma.
Trypanosomiasis, African
A novel suicide inhibitor strategy for antiparasitic drug development.
Trypanosomiasis, African
Altering the reaction specificity of eukaryotic ornithine decarboxylase.
Trypanosomiasis, African
Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense.
Trypanosomiasis, African
Further studies on difluoromethylornithine in African trypanosomes.
Trypanosomiasis, African
Insights into antitrypanosomal drug mode-of-action from cytology-based profiling.
Trypanosomiasis, African
Long-range interactions in the dimer interface of ornithine decarboxylase are important for enzyme function.
Trypanosomiasis, African
Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei.
Trypanosomiasis, African
Polyamine biosynthetic enzymes as drug targets in parasitic protozoa.
Trypanosomiasis, African
Resistance to DL-alpha-difluoromethylornithine by clinical isolates of Trypanosoma brucei rhodesiense. Role of S-adenosylmethionine.
Trypanosomiasis, African
RNA interference-mediated silencing of ornithine decarboxylase and spermidine synthase genes in Trypanosoma brucei provides insight into regulation of polyamine biosynthesis.
Trypanosomiasis, African
Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution.
Trypanosomiasis, African
Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases.
Trypanosomiasis, African
X-ray structure determination of Trypanosoma brucei ornithine decarboxylase bound to D-ornithine and to G418: insights into substrate binding and ODC conformational flexibility.
Tuberous Sclerosis
Ornithine decarboxylase, the rate-limiting enzyme of polyamine synthesis, modifies brain pathology in a mouse model of tuberous sclerosis complex.
Unconsciousness
Regional variation in the response of cerebral ornithine decarboxylase to electroconvulsive shock.
Urea Cycle Disorders, Inborn
A Proposed Physiopathological Pathway to Hyperammonemic Encephalopathy in a Non-Cirrhotic Patient with Fibrolamellar Hepatocellular Carcinoma without Ornithine Transcarbamylase (OTC) Mutation.
Uremia
Induction of intestinal mucosal atrophy by difluoromethylornithine: a nonuremic model of enhanced aluminum absorption.
Urinary Bladder Neoplasms
In vitro induction of ornithine decarboxylase in urinary bladder carcinoma cells.
Urinary Bladder Neoplasms
Randomized prospective phase III trial of difluoromethylornithine vs placebo in preventing recurrence of completely resected low risk superficial bladder cancer.
Urinary Bladder, Overactive
Management of refractory overactive bladder in children by transcutaneous posterior tibial nerve stimulation: A controlled study.
Urolithiasis
Lack of evidence for the association of ornithine decarboxylase (+316 G>A), spermidine/spermine acetyl transferase (-1415 T>C) gene polymorphisms with calcium oxalate stone disease.
Uterine Hemorrhage
Termination of pregnancy in mice with antiserum to chicken riboflavin-carrier protein.
Vaccinia
Ornithine decarboxylase activity in uninfected and vaccinia virus-infected HeLa cells.
Vascular Diseases
Polyamines and the development of monocrotaline-induced pulmonary hypertension.
Vascular Diseases
Regulation of ornithine decarboxylase by hypoxia in pulmonary artery smooth muscle cells.
Virus Diseases
Fusion of the HCMV pp65 antigen with both ubiquitin and ornithine decarboxylase additionally enhances antigen presentation to CD8+ T cells in human dendritic cells.
Virus Diseases
Induction of hypersensitive cell death by hydrogen peroxide produced through polyamine degradation in tobacco plants.
Vitamin A Deficiency
Hepatic or pulmonary ornithine decarboxylase and vitamin A status in Wistar rat, enzyme kinetics--influence of chloroform.
Vitamin A Deficiency
Mechanisms of asbestos-induced squamous metaplasia in tracheobronchial epithelial cells.
Vitamin A Deficiency
Ornithine decarboxylase basal activity in liver, oesophagus and lung of vitamin A deficient rats, and the effect of retinoic acid.
Vitamin A Deficiency
[Experimental cancerogenesis. Stimulation of ornithine decarboxylase of the colonic mucosa in vitamin A-deficient rats by sodium desoxycholate]
Vitamin A Deficiency
[Vitamin A status and the carcinogenic action of N-nitrosobenzyl methylamine on the esophagus in the rat]
Vitreoretinopathy, Proliferative
Consequences of ornithine decarboxylase inactivation by alpha-difluoromethylornithine and 5-fluorouracil on the growth of rabbit fibroblasts.
Whooping Cough
Effects of cholera and pertussis toxins on prolactin stimulation of lactose synthesis and ornithine decarboxylase activity in mouse mammary gland explants.
Whooping Cough
Involvement of a pertussis-toxin sensitive G protein in the induction of gene expression by insulin.
Whooping Cough
Platelet-derived growth factor mediated altered expression and regulation of ornithine decarboxylase in H-ras-transformed cell lines.
Whooping Cough
Stimulation of rat pancreatic tumoral AR4-2J cell proliferation by pituitary adenylate cyclase-activating peptide.
Wilms Tumor
Effects of alpha-difluoromethylornithine on the growth of experimental Wilms' tumor and renal adenocarcinoma.
Wilms Tumor
Regulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1.
Xeroderma Pigmentosum
A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients.
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Release 2023.1 (January 2023)
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