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Information on EC 4.1.1.119 - phenylacetate decarboxylase

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.119 phenylacetate decarboxylase
IUBMB Comments
This bacterial enzyme, isolated from anoxic, toluene-producing microbial communities, is a glycyl radical enzyme. It needs to be activated by a dedicated activating enzyme (PhdA). The activase catalyses the reductive cleavage of AdoMet, producing a 5'-deoxyadenosyl radical that leads to the production of the glycyl radical in PhdB.
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The expected taxonomic range for this enzyme is: uncultured bacterium
Reaction Schemes
Synonyms
phdB, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
phenylacetate = toluene + CO2
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