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Information on EC 3.7.1.8 - 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

for references in articles please use BRENDA:EC3.7.1.8

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IUBMB Comments

Cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond. Involved in the breakdown of biphenyl-related compounds by Pseudomonas sp.

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
meta-cleavage product hydrolase, mcp hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, bphd enzyme, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
2,2'-dihydroxybiphenyl degradation, 2-hydroxybiphenyl degradation, biphenyl degradation, dibenzofuran degradation