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Information on EC 3.7.1.21 - 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase

for references in articles please use BRENDA:EC3.7.1.21
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IUBMB Comments
The enzyme, which participates in the anaerobic benzoyl-CoA degradation pathway in certain organisms, catalyses the addition of one molecule of water to the double bound of 6-oxocyclohex-1-ene-1-carbonyl-CoA followed by the hydrolytic C-C cleavage of the alicyclic ring.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
6-OCH-CoA hydrolase, 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, 6-oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolase, 6-oxocylcohex-1-ene-1-carbonyl-CoA hydrolase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O = 3-hydroxypimeloyl-CoA
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6-oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O = 3-hydroxypimeloyl-CoA
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6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O = 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA
show the reaction diagram
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