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Adenocarcinoma of Lung
Targeting ?-tubulin/CCT-? complex induces apoptosis and suppresses migration and invasion of highly metastatic lung adenocarcinoma.
Alzheimer Disease
The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in A?-expressing Caenorhabditis elegans.
Anthrax
CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.
Astrocytoma
Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas.
Autoimmune Diseases
Chaperonin-containing T-complex Protein 1 Subunit ? Serves as an Autoantigen Recognized by Human V?2 ?? T Cells in Autoimmune Diseases.
Bardet-Biedl Syndrome
MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis.
Blindness
Mutation in the Zebrafish cct2 Gene Leads to Abnormalities of Cell Cycle and Cell Death in the Retina: A Model of CCT2-Related Leber Congenital Amaurosis.
Breast Neoplasms
Systematic Characterization of Expression Profiles and Prognostic Values of the Eight Subunits of the Chaperonin TRiC in Breast Cancer.
Breast Neoplasms
Two members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes.
Carcinogenesis
Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis.
Carcinogenesis
Subcellular and functional proteomic analysis of the cellular responses induced by Helicobacter pylori.
Carcinoma
Expression and significance of p53 and mdm2 in atypical intestinal metaplasia and gastric carcinoma.
Carcinoma
Expression of E-cadherin and beta-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survival.
Carcinoma
Gatric carcinoma. A prospective study of tumour differentiation correlated to surgical procedures and survival rate.
Carcinoma
[Cancer cells in the blood stream of patients with gatric carcinoma.]
Carcinoma, Hepatocellular
Prognostic Power of a Chaperonin Containing TCP-1 Subunit Genes Panel for Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
The TCP1 ring complex is associated with malignancy and poor prognosis in hepatocellular carcinoma.
Cardiovascular Diseases
Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor.
Colonic Neoplasms
A novel peptide specifically targeting the vasculature of orthotopic colorectal cancer for imaging detection and drug delivery.
Colonic Neoplasms
Characterization of TCP-1 probes for molecular imaging of colon cancer.
Colorectal Neoplasms
A novel peptide specifically targeting the vasculature of orthotopic colorectal cancer for imaging detection and drug delivery.
Colorectal Neoplasms
A novel vascular-targeting peptide for gastric cancer delivers low-dose TNF? to normalize the blood vessels and improve the anti-cancer efficiency of 5-fluorouracil.
Colorectal Neoplasms
Modulated T-complex protein 1 ? and peptidyl-prolyl cis-trans isomerase B are two novel indicators for evaluating lymph node metastasis in colorectal cancer: Evidence from proteomics and bioinformatics.
Colorectal Neoplasms
Vascular-targeted TNF? and IFN? inhibits orthotopic colorectal tumor growth.
Colorectal Neoplasms
Vascular-targeted TNF? improves tumor blood vessel function and enhances antitumor immunity and chemotherapy in colorectal cancer.
Down Syndrome
Expression patterns of chaperone proteins in cerebral cortex of the fetus with Down syndrome: dysregulation of T-complex protein 1.
Epstein-Barr Virus Infections
Proteomics Analysis of Gastric Epithelial AGS Cells Infected with Epstein-Barr Virus.
Glioma
Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas.
Hepatitis C
Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein.
Hereditary Sensory and Autonomic Neuropathies
Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy.
Infections
Human Papillomavirus infection requires the CCT Chaperonin Complex.
Infections
Identification of candidate protein markers of Bovine Parainfluenza Virus Type 3 infection using an in vitro model.
Infections
[Preliminary investigation of Helicobacter pylori infection in Linqu County of Shandong province]
Leber Congenital Amaurosis
Mutation in the Zebrafish cct2 Gene Leads to Abnormalities of Cell Cycle and Cell Death in the Retina: A Model of CCT2-Related Leber Congenital Amaurosis.
Leukemia, Myeloid, Acute
Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions.
Lymphadenopathy
Silencing P2X7 receptor downregulates the expression of TCP-1 involved in lymphoma lymphatic metastasis.
Lymphatic Metastasis
Modulated T-complex protein 1 ? and peptidyl-prolyl cis-trans isomerase B are two novel indicators for evaluating lymph node metastasis in colorectal cancer: Evidence from proteomics and bioinformatics.
Lymphatic Metastasis
Silencing P2X7 receptor downregulates the expression of TCP-1 involved in lymphoma lymphatic metastasis.
Lymphoma
Silencing P2X7 receptor downregulates the expression of TCP-1 involved in lymphoma lymphatic metastasis.
Malaria
The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol.
Neoplasm Metastasis
Modulated T-complex protein 1 ? and peptidyl-prolyl cis-trans isomerase B are two novel indicators for evaluating lymph node metastasis in colorectal cancer: Evidence from proteomics and bioinformatics.
Neoplasm Metastasis
Silencing P2X7 receptor downregulates the expression of TCP-1 involved in lymphoma lymphatic metastasis.
Neoplasms
?133p53? isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells.
Neoplasms
A novel peptide specifically targeting the vasculature of orthotopic colorectal cancer for imaging detection and drug delivery.
Neoplasms
A novel vascular-targeting peptide for gastric cancer delivers low-dose TNF? to normalize the blood vessels and improve the anti-cancer efficiency of 5-fluorouracil.
Neoplasms
Anti-tumor effect and mechanism of SEA-Fab' coupled protein on gastric tumor.
Neoplasms
Chaperonin containing TCP-1 subunit 3 is critical for gastric cancer growth.
Neoplasms
Chaperonin Containing-TCP-1 Protein Level in Breast Cancer Cells Predicts Therapeutic Application of a Cytotoxic Peptide.
Neoplasms
Chaperonin-Containing TCP1 Complex (CCT) Promotes Breast Cancer Growth Through Correlations With Key Cell Cycle Regulators.
Neoplasms
Characterization of TCP-1 probes for molecular imaging of colon cancer.
Neoplasms
Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis.
Neoplasms
Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
Neoplasms
Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.
Neoplasms
Gatric carcinoma. A prospective study of tumour differentiation correlated to surgical procedures and survival rate.
Neoplasms
Identification of the TRiC/CCT substrate binding sites uncovers the function of subunit diversity in eukaryotic chaperonins.
Neoplasms
Matrine induces papillary thyroid cancer cell apoptosis in vitro and suppresses tumor growth in vivo by downregulating miR-182-5p.
Neoplasms
Molecular and Clinical Characterization of CCT2 Expression and Prognosis via Large-Scale Transcriptome Profile of Breast Cancer.
Neoplasms
Multiple malignant primary neoplasms in patients with gatric neoplasms in the health district of León.
Neoplasms
p53: the TRiC is knowing when to fold 'em.
Neoplasms
Systematic Characterization of Expression Profiles and Prognostic Values of the Eight Subunits of the Chaperonin TRiC in Breast Cancer.
Neoplasms
The cytosolic chaperonin CCT/TRiC and cancer cell proliferation.
Neoplasms
The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex.
Neoplasms
The TCP1 ring complex is associated with malignancy and poor prognosis in hepatocellular carcinoma.
Neoplasms
Tumorigenic mutations in VHL disrupt folding in vivo by interfering with chaperonin binding.
Neoplasms
Understanding the Molecular Mechanism of miR-877-3p Could Provide Potential Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma of the Cervix.
Neoplasms
Vascular-targeted TNF? and IFN? inhibits orthotopic colorectal tumor growth.
Neoplasms
Vascular-targeted TNF? improves tumor blood vessel function and enhances antitumor immunity and chemotherapy in colorectal cancer.
Neoplasms
[Cancer cells in the blood stream of patients with gatric carcinoma.]
Neoplasms
[Effects of RNA interference of CTHRC1 on proliferation and apoptosis of thyroid papillary cancer TCP-1 cells in vitro].
Neoplasms
[Preliminary investigation of Helicobacter pylori infection in Linqu County of Shandong province]
Neoplasms
[Prescription rules of Chinese herbal medicines in treatment of gastric cancer]
Neurodegenerative Diseases
Sirt1s beneficial roles in neurodegenerative diseases - a chaperonin containing TCP-1 (CCT) connection?
Neurofibromatoses
Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress.
Neurofibromatosis 1
Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress.
Papillomavirus Infections
Human Papillomavirus infection requires the CCT Chaperonin Complex.
Pleural Effusion
Identification of 10 Candidate Biomarkers Distinguishing Tuberculous and Malignant Pleural Fluid by Proteomic Methods.
Pleural Effusion, Malignant
Identification of 10 Candidate Biomarkers Distinguishing Tuberculous and Malignant Pleural Fluid by Proteomic Methods.
Pulmonary Disease, Chronic Obstructive
Effects of genetic variations in Acads gene on the risk of chronic obstructive pulmonary disease.
Starvation
Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response.
Stomach Diseases
Subcellular and functional proteomic analysis of the cellular responses induced by Helicobacter pylori.
Stomach Neoplasms
A novel vascular-targeting peptide for gastric cancer delivers low-dose TNF? to normalize the blood vessels and improve the anti-cancer efficiency of 5-fluorouracil.
Stomach Neoplasms
Chaperonin containing TCP-1 subunit 3 is critical for gastric cancer growth.
Stroke
A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle.
Teratozoospermia
T-complex protein 1 subunit zeta-2 (CCT6B) deficiency induces murine teratospermia.
Thyroid Neoplasms
Effect of Interferon-? on the Basal and the TNF?-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation.
Tuberculosis
Duodenal tuberculosis presenting as gatric outlet obstruction.
Zika Virus Infection
TRiC/CCT Complex, a Binding Partner of NS1 Protein, Supports the Replication of Zika Virus in Both Mammalians and Mosquitoes.
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3.6.4.B10 chaperonin ATPase (protein-folding, protecting from aggregation, protein stabilizing)
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
