Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Aberrant Crypt Foci
Modulation of intestinal environment by prebiotic germinated barley foodstuff prevents chemo-induced colonic carcinogenesis in rats.
Abortion, Habitual
Expression pattern of PRM2, HSP90 and WNT5A in male partners of couples experiencing idiopathic recurrent miscarriages.
Abortion, Habitual
Recurrent miscarriages, innate immunity, and autoimmune reaction to chlamydial 60-kDa heat shock protein-is there an association?
Abortion, Missed
Potential role of heat-shock protein 70 and interleukin-15 in the pathogenesis of threatened spontaneous abortions.
Abortion, Missed
Serum interleukin-1?, interleukin-8 and anti-heat shock 60 Chlamydia trachomatis antibodies as markers of ectopic pregnancy.
Abortion, Spontaneous
A comparison in concentration of heat shock proteins (HSP) 70 and 90 on chorionic villi of human placenta in normal pregnancies and in missed miscarriages.
Abortion, Spontaneous
Cell-mediated immunity to human and Escherichia coli 60-kDa heat shock protein in women: association with a history of spontaneous abortion and endometriosis.
Abortion, Spontaneous
Circulating antibodies to a conserved epitope of the Chlamydia trachomatis 60 kDa heat shock protein (hsp60) in infertile couples and its relationship to antibodies to C.trachomatis surface antigens and the Escherichia coli and human HSP60.
Abortion, Spontaneous
Early changes of the heat-shock protein 60 to 70 ratio as prediction of miscarriage in pregnancy.
Abortion, Spontaneous
Immune Recognition of the 60kD Heat Shock Protein: Implications for Subsequent Fertility.
Abortion, Spontaneous
Potential role of heat-shock protein 70 and interleukin-15 in the pathogenesis of threatened spontaneous abortions.
Abortion, Spontaneous
The contribution of placental oxidative stress to early pregnancy failure.
Abortion, Spontaneous
The study of the relationship between aberrant expression of hot shock protein 70 (HSP70) and spontaneous abortion.
Abortion, Spontaneous
Trophoblastic oxidative stress in relation to temporal and regional differences in maternal placental blood flow in normal and abnormal early pregnancies.
Abscess
Heat-shock protein HSP70-2 genotypes in patients with Crohn's disease: a more severe clinical course with intestinal complications in presence of the PstI-polymorphism.
Abscess
Serum biomarkers of Burkholderia mallei infection elucidated by proteomic imaging of skin and lung abscesses.
Acidosis
Acidosis acts through HSP90 in a PHD/VHL-independent manner to promote HIF function and stem cell maintenance in glioma.
Acidosis
Astrocyte survival and HSP70 heat shock protein induction following heat shock and acidosis.
Acidosis
Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis.
Acidosis
Cytoprotective effects of acidosis via heat shock protein HSP27 against the anticancer drug doxorubicin.
Acidosis
Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma.
Acidosis
Heat-shock proteins expression in fish central nervous system and its possible relation with water acidosis resistance.
Acidosis
Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors.
Acidosis
Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment.
Acidosis, Lactic
Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis.
Acidosis, Lactic
Glucose regulated protein 78: A critical link between tumor microenvironment and cancer hallmarks.
Acidosis, Lactic
Identification of the Transmembrane Glucose Regulated Protein 78 as a Biomarker for the Brain Cancer Glioblastoma Multiforme by Gene Expression and Proteomic Studies.
Acne Vulgaris
Heat shock proteins and inflammatory acne vulgaris: molecular cloning, overexpression and purification of a propionibacterium acnes GroEL and DnaK homologue.
Acne Vulgaris
Proinflammatory cytokine production by human keratinocytes stimulated with Propionibacterium acnes and P. acnes GroEL.
Acquired Immunodeficiency Syndrome
(-)- Epigallocatechin-3-gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress.
Acquired Immunodeficiency Syndrome
Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions.
Acquired Immunodeficiency Syndrome
Assembly of heterodimeric luciferase after de novo synthesis of subunits in rabbit reticulocyte lysate involves hsc70 and hsp40 at a post-translational stage.
Acquired Immunodeficiency Syndrome
ATP-Driven Nonequilibrium Activation of Kinase Clients by the Molecular Chaperone Hsp90.
Acquired Immunodeficiency Syndrome
Comparative analysis of differential gene expression of HSP40 and HSP70 family isoforms during heat stress and HIV-1 infection in T-cells.
Acquired Immunodeficiency Syndrome
Endocytic Trafficking of DMP1 and GRP78 Complex Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells.
Acquired Immunodeficiency Syndrome
Hsp90 Maintains Proteostasis of the Galactose Utilization Pathway To Prevent Cell Lethality.
Acquired Immunodeficiency Syndrome
Identification of Genes Whose Expression Profile Is Associated with Non-Progression towards AIDS Using eQTLs.
Acquired Immunodeficiency Syndrome
Interaction mechanism of Mycobacterium tuberculosis GroEL2 protein with macrophage Lectin-like, oxidized low-density lipoprotein receptor-1: An integrated computational and experimental study.
Acquired Immunodeficiency Syndrome
Interaction of vanadate oligomers and permolybdate with the 90-kDa heat-shock protein, Hsp90.
Acquired Immunodeficiency Syndrome
Modulation of heat shock protein 90 affects TGF-?-induced collagen synthesis in human dermal fibroblast cells.
Acquired Immunodeficiency Syndrome
Phenotypic diversity and altered environmental plasticity in Arabidopsis thaliana with reduced Hsp90 levels.
Acquired Immunodeficiency Syndrome
Pre-exercise alkalosis attenuates the heat shock protein 72 response to a single-bout of anaerobic exercise.
Acquired Immunodeficiency Syndrome
Protein structural transitions and their functional role.
Acquired Immunodeficiency Syndrome
The co-chaperone Cdc37 regulates the rabies virus phosphoprotein stability by targeting to Hsp90AA1 machinery.
Acquired Immunodeficiency Syndrome
The G?-interacting vesicle-associated protein interacts with and promotes cell surface localization of GRP78 during endoplasmic reticulum stress.
Acquired Immunodeficiency Syndrome
The Small Heat Shock Protein p26 Aids Development of Encysting Artemia Embryos, Prevents Spontaneous Diapause Termination and Protects against Stress.
Acquired Immunodeficiency Syndrome
To fold or not to fold: modulation and consequences of Hsp90 inhibition.
ACTH-Secreting Pituitary Adenoma
A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease.
ACTH-Secreting Pituitary Adenoma
Advances in the medical treatment of Cushing's syndrome.
ACTH-Secreting Pituitary Adenoma
Recent advances in understanding corticotroph pituitary tumor initiation and progression.
Acute Coronary Syndrome
Antibody titres to heat shock protein 27 are elevated in patients with acute coronary syndrome.
Acute Coronary Syndrome
Association of plasma concentration of small heat shock protein b7 with acute coronary syndrome.
Acute Coronary Syndrome
Changes in Plasma Level of Heat Shock Protein 27 After Acute Coronary Syndrome.
Acute Coronary Syndrome
Expression of heat shock protein 27 in human atherosclerotic plaques and increased plasma level of heat shock protein 27 in patients with acute coronary syndrome.
Acute Coronary Syndrome
Inverse association of ApoB and HSP60 antibodies with coronary artery disease in Indian population.
Acute Kidney Injury
Activation of AMP-activated protein kinase inhibits ER stress and renal fibrosis.
Acute Kidney Injury
Acute Kidney Injury, an Id Reaction and HSP90.
Acute Kidney Injury
Association between heat shock protein 72 gene polymorphism and acute renal failure in premature neonates.
Acute Kidney Injury
Association of HSP73 with the acquired resistance to uranyl acetate-induced acute renal failure.
Acute Kidney Injury
Down-regulation of GRP78 alleviates lipopolysaccharide-induced acute kidney injury.
Acute Kidney Injury
Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.
Acute Kidney Injury
Glutamine attenuates tubular cell apoptosis in acute kidney injury via inhibition of the c-Jun N-terminal kinase phosphorylation of 14-3-3*
Acute Kidney Injury
Heat Shock Protein 27 Is an Emerging Predictor of Contrast-Induced Acute Kidney Injury on Patients Subjected to Percutaneous Coronary Interventions.
Acute Kidney Injury
Heat shock protein 72 (Hsp72) specific induction and temporal stability in urine samples as a reliable biomarker of acute kidney injury (AKI).
Acute Kidney Injury
Hsp72 is a novel biomarker to predict acute kidney injury in critically ill patients.
Acute Kidney Injury
Hsp72 is an early and sensitive biomarker to detect acute kidney injury.
Acute Kidney Injury
Hsp90 Relieves Heat Stress-Induced Damage in Mouse Kidneys: Involvement of Antiapoptotic PKM2-AKT and Autophagic HIF-1? Signaling.
Acute Kidney Injury
Human heat shock protein 27-overexpressing mice are protected against acute kidney injury after hepatic ischemia and reperfusion.
Acute Kidney Injury
Induction and altered localization of 90-kDa heat-shock protein in rat kidneys with cisplatin-induced acute renal failure.
Acute Kidney Injury
Mediators and mechanisms of heat shock protein 70 based cytoprotection in obstructive nephropathy.
Acute Kidney Injury
NLRP3 expression and urinary HSP72 in relation to biomarkers of inflammation and oxidative stress in diabetic nephropathy patients.
Acute Kidney Injury
Perioperative urinary heat shock protein 72 as an early marker of acute kidney injury in dogs.
Acute Kidney Injury
Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury.
Acute Kidney Injury
Tubular Urinary Biomarkers Do Not Identify Etiology of Acute Kidney Injury in Kidney Transplant Recipients.
Acute Kidney Injury
Urinary heat shock protein 72 as a biomarker of acute kidney injury in dogs.
Acute Kidney Injury
Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplant.
Acute Lung Injury
Activation of the stress protein response inhibits the STAT1 signalling pathway and iNOS function in alveolar macrophages: role of Hsp90 and Hsp70.
Acute Lung Injury
Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.
Acute Lung Injury
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice.
Acute Lung Injury
Heat shock response and acute lung injury.
Acute Lung Injury
Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.
Acute Lung Injury
Hypobaric hypoxia preconditioning attenuates acute lung injury during high-altitude exposure in rats via up-regulating heat-shock protein 70.
Acute Lung Injury
Isthmin is a novel vascular permeability inducer that functions through cell-surface GRP78-mediated Src activation.
Acute Lung Injury
Overexpression of heat shock protein 70 enhanced mesenchymal stem cell treatment efficacy in phosgene-induced acute lung injury.
Acute Lung Injury
Serum levels of Hsp60 correlate with the development of acute lung injury after trauma.
Acute Lung Injury
Somatostatin Reduces the Acute Lung Injury of Mice via Increasing the Affinity of Glucocorticoid Receptor.
Acute Lung Injury
The 150-kilodalton oxygen-regulated protein ameliorates lipopolysaccharide-induced acute lung injury in mice.
Acute Lung Injury
The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction.
Acute Lung Injury
[Association of glucocoid receptor binding activity and heat shock protein expressions after acute lung injury in mice]
Acute Lung Injury
[Effects of over-expressing heat shock protein 60 on marrow mesenchymal stem cells in the treatment of phosgene-induced acute lung injury].
Addison Disease
Sequence homologies between hsp60 and autoantigens.
Adenocarcinoma
18?-Glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.
Adenocarcinoma
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
Adenocarcinoma
A phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma.
Adenocarcinoma
Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.
Adenocarcinoma
Chaperonin (HSP60) and annexin-2 are candidate biomarkers for non-small cell lung carcinoma.
Adenocarcinoma
Clinical significance of heat shock proteins in gastric cancer following hyperthermia stress: Indications for hyperthermic intraperitoneal chemoperfusion therapy.
Adenocarcinoma
CLPTM1L/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells.
Adenocarcinoma
Comparative analysis of Hsp10 and Hsp90 expression in healthy mucosa and adenocarcinoma of the large bowel.
Adenocarcinoma
Comparison of the desmoplastic reaction and invading ability in invasive ductal carcinoma of the breast and prostatic adenocarcinoma based on the expression of heat shock protein 47 and fascin.
Adenocarcinoma
Correlation between clinicopathology and expression of heat shock protein 70 and glucose-regulated protein 94 in human colonic adenocarcinoma.
Adenocarcinoma
Correlation between clinicopathology and expression of heat shock protein 72 and glycoprotein 96 in human gastric adenocarcinoma.
Adenocarcinoma
Cytoplasmic sequestration of the tumor suppressor p53 by a heat shock protein 70 family member, mortalin, in human colorectal adenocarcinoma cell lines.
Adenocarcinoma
Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer.
Adenocarcinoma
Different expression of CD44, ICAM-1, and HSP60 on primary tumor and metastases of a human pancreatic carcinoma growing in scid mice.
Adenocarcinoma
Effectiveness of HSV-tk suicide gene therapy driven by the Grp78 stress-inducible promoter in esophagogastric junction and gastric adenocarcinomas.
Adenocarcinoma
Effects of geldanamycin and other naturally occurring small molecule antagonists of heat shock protein 90 on HER2 protein expression.
Adenocarcinoma
Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer.
Adenocarcinoma
Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter.
Adenocarcinoma
Estrogen receptor gene expression and its relation to the estrogen-inducible HSP27 heat shock protein in hormone refractory prostate cancer.
Adenocarcinoma
Evidence for downregulation of calcium signaling proteins in advanced mouse adenocarcinoma.
Adenocarcinoma
Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas.
Adenocarcinoma
Expression and clinical significance of glucose regulated proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus.
Adenocarcinoma
Expression and localization of GRP75 in human epithelial tumors and normal tissues.
Adenocarcinoma
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions.
Adenocarcinoma
Expression Of GRP78, Master Regulator Of The Unfolded Protein Response, Increases Chemoresistance In Pancreatic Ductal Adenocarcinoma.
Adenocarcinoma
Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung.
Adenocarcinoma
Forced expression of heat-shock protein 70 increases the secretion of Hsp70 and provides protection against tumour growth.
Adenocarcinoma
Gene expression profiling identifies markers of ampullary adenocarcinoma.
Adenocarcinoma
Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway.
Adenocarcinoma
GRP78 expression and prognostic significance in patients with pancreatic ductal adenocarcinoma treated with neoadjuvant therapy versus surgery first.
Adenocarcinoma
Heat shock protein 105 is overexpressed in a variety of human tumors.
Adenocarcinoma
Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma.
Adenocarcinoma
Heat shock protein 27 is over-expressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma.
Adenocarcinoma
Heat shock protein 70 (HSP70) after laser thermotherapy of an adenocarcinoma transplanted into rat liver.
Adenocarcinoma
Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma.
Adenocarcinoma
Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer.
Adenocarcinoma
Heat shock protein 72 associated with CD44v6 in human colonic adenocarcinoma.
Adenocarcinoma
Heat shock protein 72/73 in relation to cytoplasmic p53 expression and prognosis in colorectal adenocarcinomas.
Adenocarcinoma
Heat Shock Protein 90 (HSP90) and Her2 in Adenocarcinomas of the Esophagus.
Adenocarcinoma
Heat Shock Protein 90 Inhibitor Effects on Pancreatic Cancer Cell Cultures.
Adenocarcinoma
Heat shock protein beta 3 (HSPB3) is an unfavorable molecular biomarker in colorectal adenocarcinoma.
Adenocarcinoma
Heat shock protein expression independently predicts clinical outcome in prostate cancer.
Adenocarcinoma
Heat shock protein HSP90 and its association with the cytoskeleton: a morphological study.
Adenocarcinoma
HSP 70 induction and thermotolerance following interstitial hyperthermia in the dunning R3327 tumor in vivo.
Adenocarcinoma
Hsp-27 has no diagnostic or prognostic significance in prostate or bladder cancers.
Adenocarcinoma
Hsp27 Protects Adenocarcinoma Cells from UV-Induced Apoptosis by Akt and p21-Dependent Pathways of Survival.
Adenocarcinoma
Hsp60 and Hsp10 down-regulation predicts bronchial epithelial carcinogenesis in smokers with chronic obstructive pulmonary disease.
Adenocarcinoma
Hsp90 inhibitor geldanamycin increases the sensitivity of resistant ovarian adenocarcinoma cell line A2780cis to cisplatin.
Adenocarcinoma
HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line.
Adenocarcinoma
Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.
Adenocarcinoma
Immunohistochemical detection of pS2 protein and heat shock protein-70 in pancreatic adenocarcinomas. Relationship with disease extent and patient survival.
Adenocarcinoma
Immunohistochemical evaluation of PCNA, p53, HSP60, HSP10 and MUC-2 presence and expression in prostate carcinogenesis.
Adenocarcinoma
Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47.
Adenocarcinoma
Immunolocalisation of heat shock protein 72 and glycoprotein 96 in colonic adenocarcinoma.
Adenocarcinoma
Induced oxidative stress and decreased expression of inducible heat shock protein 70 (ihsp 70) in patients with colorectal adenocarcinomas.
Adenocarcinoma
Influence of HSP27 and steroid receptor status on provera sensitivity, DNA-ploidy and survival of females with endometrial cancer.
Adenocarcinoma
Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4'fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells.
Adenocarcinoma
Irreversible UV inactivation of Cryptosporidium spp. despite the presence of UV repair genes.
Adenocarcinoma
l-Arginine supplementation prevents intestinal epithelial barrier breakdown under heat stress conditions by promoting nitric oxide synthesis.
Adenocarcinoma
Mortalin expression in pancreatic cancer and its clinical and prognostic significance.
Adenocarcinoma
Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival.
Adenocarcinoma
Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability.
Adenocarcinoma
Novel colorectal adenocarcinoma-associated 40- and 47-kDa protein antigens recognized by anti-60-kDa heat shock protein antibody.
Adenocarcinoma
Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth.
Adenocarcinoma
Overexpression of endoplasmic reticulum stress-related proteins, XBP1s and GRP78, predicts poor prognosis in pulmonary adenocarcinoma.
Adenocarcinoma
Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo.
Adenocarcinoma
P53 and heat shock protein 70 expressions in colorectal adenocarcinoma.
Adenocarcinoma
Phenethyl isothiocyanate, by virtue of its antioxidant activity, inhibits invasiveness and metastatic potential of breast cancer cells: HIF-1? as a putative target.
Adenocarcinoma
Preclinical Study of AUY922, a Novel Hsp90 Inhibitor, in the Treatment of Esophageal Adenocarcinoma.
Adenocarcinoma
Prognostic significance of heat shock protein 70 expression in early gastric carcinoma.
Adenocarcinoma
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Adenocarcinoma
Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.
Adenocarcinoma
Role of GRP78 inhibiting artesunate-induced ferroptosis in KRAS mutant pancreatic cancer cells.
Adenocarcinoma
Role of increased basal expression of heat shock protein 72 in colonic epithelial c2BBE adenocarcinoma cells.
Adenocarcinoma
Significance of unphosphorylated and phosphorylated heat shock protein 27 as a prognostic biomarker in pancreatic ductal adenocarcinoma.
Adenocarcinoma
The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells.
Adenocarcinoma
The Prognostic Impact of Heat Shock Proteins Expression in Patients with Esophageal Cancer: A Meta-Analysis.
Adenocarcinoma
TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas.
Adenocarcinoma
Truncated O-glycans promote epithelial-to-mesenchymal transition and stemness properties of pancreatic cancer cells.
Adenocarcinoma
Tumor prevention and antitumor immunity with heat shock protein 70 induced by 15-deoxy-delta12,14-prostaglandin J2 in transgenic adenocarcinoma of mouse prostate cells.
Adenocarcinoma
Up-regulation of heat shock protein 70 in adenocarcinomas of the lung in smokers.
Adenocarcinoma
Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.
Adenocarcinoma in Situ
Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung.
Adenocarcinoma of Lung
??? kinase ? is required for development and progression of KRAS-mutant lung adenocarcinoma.
Adenocarcinoma of Lung
A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma.
Adenocarcinoma of Lung
Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies.
Adenocarcinoma of Lung
Correction: EGFR Exon 20 Insertion Mutations Display Sensitivity to Hsp90 Inhibition in Preclinical Models and Lung Adenocarcinomas.
Adenocarcinoma of Lung
Docosahexaenoic Acid-mediated Inhibition of Heat Shock Protein 90-p23 Chaperone Complex and Downstream Client Proteins in Lung and Breast Cancer.
Adenocarcinoma of Lung
EGFR Exon 20 Insertion Mutations Display Sensitivity to Hsp90 Inhibition in Preclinical Models and Lung Adenocarcinomas.
Adenocarcinoma of Lung
GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78.
Adenocarcinoma of Lung
Ganetespib AIDS lung cancer survival.
Adenocarcinoma of Lung
Glucose-Regulated Protein 78 Signaling Regulates Hypoxia-Induced Epithelial-Mesenchymal Transition in A549 Cells.
Adenocarcinoma of Lung
Heat shock protein 90-? over-expression is associated with poor survival in stage I lung adenocarcinoma patients.
Adenocarcinoma of Lung
Heat shock protein B8 promotes proliferation and migration in lung adenocarcinoma A549 cells by maintaining mitochondrial function.
Adenocarcinoma of Lung
Heat shock protein-60 expression was significantly correlated with the prognosis of lung adenocarcinoma.
Adenocarcinoma of Lung
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance.
Adenocarcinoma of Lung
Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines.
Adenocarcinoma of Lung
Identification of Predictive Biomarkers of Response to HSP90 Inhibitors in Lung Adenocarcinoma.
Adenocarcinoma of Lung
Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry.
Adenocarcinoma of Lung
Inhibition of ALK, PI3K/MEK and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene.
Adenocarcinoma of Lung
Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
Adenocarcinoma of Lung
Opposite Regulation of CHOP and GRP78 and Synergistic Apoptosis Induction by Selenium Yeast and Fish Oil via AMPK Activation in Lung Adenocarcinoma Cells.
Adenocarcinoma of Lung
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.
Adenocarcinoma of Lung
Prognostic significance of heat shock protein 105 in lung adenocarcinoma.
Adenocarcinoma of Lung
Prognostic value of Mortalin correlates with roles in epithelial-mesenchymal transition and angiogenesis in lung adenocarcinoma.
Adenocarcinoma of Lung
Promising Targets and Current Clinical Trials in Metastatic Non-Squamous NSCLC.
Adenocarcinoma of Lung
Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition.
Adenocarcinoma of Lung
The antitumor agent PBT-1 directly targets HSP90 and hnRNP A2/B1 and inhibits lung adenocarcinoma growth and metastasis.
Adenocarcinoma of Lung
The expression and clinical significance of CLIC1 and HSP27 in lung adenocarcinoma.
Adenocarcinoma of Lung
The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells.
Adenocarcinoma of Lung
Ubiquitination of heat shock protein 27 is mediated by its interaction with Smad ubiquitination regulatory factor 2 in A549 cells.
Adenocarcinoma of Lung
[Different proteome of human lung adenocarcinoma cells treated with NS-398 and cisplation.]
Adenocarcinoma of Lung
[Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung Adenocarcinoma.]
Adenocarcinoma of Lung
[Expression profile of heat shock proteins in tissues and cells of lung adenocarcinoma]
Adenocarcinoma of Lung
[RNA Interference targeting GRP75 decreases cisplatin resistance in human lung adenocarcinoma cell].
Adenocarcinoma, Follicular
Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells.
Adenocarcinoma, Mucinous
BAG-1/SODD, HSP70 and HSP90 are potential prognostic markers of poor survival in node-negative breast carcinoma.
Adenocarcinoma, Mucinous
Clinicopathological and genetic characteristics of mucinous carcinomas in the colorectum.
Adenocarcinoma, Mucinous
Expression of heat shock protein 90 beta in human gastric cancer tissue and SGC7901/VCR of MDR-type gastric cancer cell line.
Adenocarcinoma, Scirrhous
Immunohistochemical distribution of heat shock protein 47 (HSP47) in scirrhous carcinoma of the stomach.
Adenoma
60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis.
Adenoma
Endoplasmic Reticulum Chaperone Calmegin Is Upregulated in Aldosterone-Producing Adenoma and Associates With Aldosterone Production.
Adenoma
Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.
Adenoma
Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis.
Adenoma
Heterozygosity of chaperone Grp78 reduces intestinal stem cell regeneration potential and protects against adenoma formation.
Adenoma
Immunohistochemical evaluation of expression of heat shock proteins HSP70 and HSP90 in mammary gland neoplasms in bitches.
Adenoma
Impact of USP8 Gene Mutations on Protein Deregulation in Cushing Disease.
Adenoma
Overexpression of glucose-regulated protein 78 in colon cancer.
Adenoma
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
Adenoma
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Adenoma
Protein western array analysis in human pituitary tumours: insights and limitations.
Adenoma
Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.
Adenoma
Regression of intestinal adenomas by vaccination with heat shock protein 105-pulsed bone marrow-derived dendritic cells in Apc(Min/+) mice.
Adenoma, Islet Cell
Inhibition of Heat Shock Protein 90 with AUY922 Represses Tumor Growth in a Transgenic Mouse Model of Islet Cell Neoplasms.
Adenoma, Liver Cell
Characteristic upregulation of glucose-regulated protein 78 in an early lesion negative for hitherto established cytochemical markers in rat hepatocarcinogenesis.
Adenoma, Liver Cell
Combined use of heat-shock protein 70 and glutamine synthetase is useful in the distinction of typical hepatocellular adenoma from atypical hepatocellular neoplasms and well-differentiated hepatocellular carcinoma.
Adenoma, Liver Cell
Hepatocellular carcinoma arising in adenoma: similar immunohistochemical and cytogenetic features in adenoma and hepatocellular carcinoma portions of the tumor.
Adenomatous Polyposis Coli
GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the ?-catenin signaling.
Adenomatous Polyposis Coli
Protein disulfide bond formation in the cytoplasm during oxidative stress.
Adenomatous Polyposis Coli
The origins of rimmed vacuoles and granulovacuolar degeneration bodies are associated with the Wnt signaling pathway.
Adenomyosis
Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy.
Adenomyosis
Distribution of heat shock proteins in eutopic and ectopic endometrium in endometriosis and adenomyosis.
Adenosarcoma
Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
Adrenocortical Carcinoma
A novel heat shock protein 90 inhibitor potently targets adrenocortical carcinoma tumor suppression.
Adrenocortical Carcinoma
Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma.
Adrenocortical Carcinoma
Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane.
Adrenocortical Carcinoma
Potent antitumor activity of HSP90 inhibitor AUY922 in adrenocortical carcinoma.
Adrenoleukodystrophy
Heat shock protein expression in cerebral X-linked adrenoleukodystrophy reveals astrocyte stress prior to myelin loss.
African Swine Fever
The African swine fever virus nonstructural protein pB602L is required for formation of the icosahedral capsid of the virus particle.
Aggressive Periodontitis
Association between circulating levels of heat-shock protein 27 and aggressive periodontitis.
Agranulocytosis
HSP70-2 9.0 kb variant is in linkage disequilibrium with the HLA-B and DRB1* alleles associated with clozapine-induced agranulocytosis.
Agranulocytosis
Mechanism of clozapine-induced agranulocytosis : current status of research and implications for drug development.
Agranulocytosis
The major histocompatibility complex region marked by HSP70-1 and HSP70-2 variants is associated with clozapine-induced agranulocytosis in two different ethnic groups.
Albuminuria
Heat shock protein 70 and albuminuria in patients with type 2 diabetes: a matched case control study.
Albuminuria
Levels of circulating GRP78 and CHOP in endoplasmic reticulum stress pathways in Chinese type 2 diabetic kidney disease patients.
Albuminuria
Protective role of podocyte autophagy against glomerular endothelial dysfunction in diabetes.
Albuminuria
The lost correlation between heat shock protein 70 (HSPA1A) and plasminogen activator inhibitor-1 in patients with type 2 diabetes and albuminuria.
Alexander Disease
Adolescent case of Alexander disease: MR imaging and MR spectroscopy.
Alexander Disease
Alpha B-crystallin and 27-kd heat shock protein are regulated by stress conditions in the central nervous system and accumulate in Rosenthal fibers.
Alexander Disease
Clinical aspects and pathology of Alexander disease, and morphological and functional alteration of astrocytes induced by GFAP mutation.
Alexander Disease
Cytokines and growth factors induce HSP27 phosphorylation in human astrocytes.
Alexander Disease
Oligomers of mutant glial fibrillary acidic protein (GFAP) Inhibit the proteasome system in alexander disease astrocytes, and the small heat shock protein alphaB-crystallin reverses the inhibition.
Alexander Disease
Positron emission tomography in juvenile Alexander disease.
Alkalosis
Heat shock protein synthesis is affected by intracellular pH: inhibition by monensin-induced alkalosis in C6 rat glioma cells.
Alkalosis
Pre-exercise alkalosis attenuates the heat shock protein 72 response to a single-bout of anaerobic exercise.
Alkalosis
The influence of exogenous carbohydrate provision and pre-exercise alkalosis on the heat shock protein response to prolonged interval cycling.
Alopecia
Recombinant human Cyclophilin A stimulates hair follicle cells via Wnt/?-catenin signaling pathway.
Alphavirus Infections
Proteomic Discovery of VEEV E2-Host Partner Interactions Identifies GRP78 Inhibitor HA15 as a Potential Therapeutic for Alphavirus Infections.
Altitude Sickness
High altitude hypoxia on brain ultrastructure of rats and Hsp70 expression changes.
Altitude Sickness
[Relationship between heat stress protein 70 gene polymorphisms and the risk of acute mountain sickness]
Alveolar Bone Loss
Porphyromonas gingivalis heat shock protein vaccine reduces the alveolar bone loss induced by multiple periodontopathogenic bacteria.
Alveolitis, Extrinsic Allergic
Expression of heat shock protein 72 by alveolar macrophages in hypersensitivity pneumonitis.
Alzheimer Disease
A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.
Alzheimer Disease
A hypothesis on the aetiology of Alzheimer's disease: description of a model involving a misfolded chaperone.
Alzheimer Disease
A New Motif in the N-Terminal of Acetylcholinesterase Triggers Amyloid-? Aggregation and Deposition.
Alzheimer Disease
A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity.
Alzheimer Disease
Acceleration of TDP43 and FUS/TLS protein expressions in the preconditioned hippocampus following repeated transient ischemia.
Alzheimer Disease
Acupuncture promotes expression of Hsp84/86 and delays brain ageing in SAMP8 mice.
Alzheimer Disease
Alpha 1-antichymotrypsin gene polymorphism and risk for Alzheimer's disease.
Alzheimer Disease
Alpha B crystallin and HSP28 are enhanced in the cerebral cortex of patients with Alzheimer's disease.
Alzheimer Disease
Aluminium exposure induces Alzheimer's disease-like histopathological alterations in mouse brain.
Alzheimer Disease
Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.
Alzheimer Disease
Analysis of HSPA8 and HSPA9 mRNA Expression and Promoter Methylation in the Brain and Blood of Alzheimer's Disease Patients.
Alzheimer Disease
Analysis of the Tau-Associated Proteome Reveals That Exchange of Hsp70 for Hsp90 Is Involved in Tau Degradation.
Alzheimer Disease
Applying Hsp104 to protein-misfolding disorders.
Alzheimer Disease
Association of HSP70 and its Co-Chaperones with Alzheimer's Disease.
Alzheimer Disease
BDNF, TNF?, HSP90, CFH, and IL-10 Serum Levels in Patients with Early or Late Onset Alzheimer's Disease or Mild Cognitive Impairment.
Alzheimer Disease
Binding of the molecular chaperone ?B-crystallin to A? amyloid fibrils inhibits fibril elongation.
Alzheimer Disease
Chaperones increase association of tau protein with microtubules.
Alzheimer Disease
Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation.
Alzheimer Disease
Clusterin as a therapeutic target.
Alzheimer Disease
Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
Alzheimer Disease
Development of GMP-1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer's disease.
Alzheimer Disease
Down-regulation of mortalin exacerbates A?-mediated mitochondrial fragmentation and dysfunction.
Alzheimer Disease
Elevated risks for amyotrophic lateral sclerosis and blood disorders in Ashkenazi schizophrenic pedigrees suggest new candidate genes in schizophrenia.
Alzheimer Disease
ER chaperone-metal interactions: Links to protein folding disorders.
Alzheimer Disease
Expression of the human groEL stress-protein homologue in the brain and spinal cord.
Alzheimer Disease
Heat Shock Cognate 70 Inhibitor, VER-155008, Reduces Memory Deficits and Axonal Degeneration in a Mouse Model of Alzheimer's Disease.
Alzheimer Disease
Heat shock protein 70 and tumor necrosis factor alpha in Taiwanese patients with dementia.
Alzheimer Disease
Heat shock protein 70 in Alzheimer's disease.
Alzheimer Disease
Heat shock protein 90 in Alzheimer's disease.
Alzheimer Disease
Heat shock protein 90: its inhibition and function.
Alzheimer Disease
Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?
Alzheimer Disease
Heat Shock Protein Inspired Nanochaperones Restore Amyloid-? Homeostasis for Preventative Therapy of Alzheimer's Disease.
Alzheimer Disease
Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro.
Alzheimer Disease
Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease.
Alzheimer Disease
Hot off the Press.
Alzheimer Disease
HSP70-2 (HSPA1B) is associated with noncognitive symptoms in late-onset Alzheimer's disease.
Alzheimer Disease
Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases.
Alzheimer Disease
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Alzheimer Disease
Hsp90 modulation for the treatment of Alzheimer's disease.
Alzheimer Disease
Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease.
Alzheimer Disease
HSPA9/Mortalin mediates axo-protection and modulates mitochondrial dynamics in neurons.
Alzheimer Disease
Human olfactory receptor neurons express heat shock protein 70: age-related trends.
Alzheimer Disease
Intake of ?-6 Polyunsaturated Fatty Acid-Rich Vegetable Oils and Risk of Lifestyle Diseases.
Alzheimer Disease
Lack of association of mortalin (HSPA9) and other mitochondria-related genes with risk of Parkinson's and Alzheimer's diseases.
Alzheimer Disease
Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain.
Alzheimer Disease
Low endogenous and chemical induced heat shock protein induction in a 0N3Rtau-expressing Drosophila larval model of Alzheimer's disease.
Alzheimer Disease
Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.
Alzheimer Disease
MicroRNA-425-5p promotes tau phosphorylation and cell apoptosis in Alzheimer's disease by targeting heat shock protein B8.
Alzheimer Disease
Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1.
Alzheimer Disease
Molecular chaperone inducer: a possible treatment for Alzheimer disease.
Alzheimer Disease
Mortalin is Expressed by Astrocytes and Decreased in the Midbrain of Parkinson's Disease Patients.
Alzheimer Disease
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
Alzheimer Disease
Probing the mechanism of inhibition of amyloid-?(1-42)-induced neurotoxicity by the chaperonin GroEL.
Alzheimer Disease
Recent Advances in Stereoselective Drug Targeting.
Alzheimer Disease
Small heat shock protein HspB8: its distribution in Alzheimer's disease brains and its inhibition of amyloid-beta protein aggregation and cerebrovascular amyloid-beta toxicity.
Alzheimer Disease
Stressing Out Hsp90 in Neurotoxic Proteinopathies.
Alzheimer Disease
Sulforaphane Upregulates the Heat Shock Protein Co-Chaperone CHIP and Clears Amyloid-? and Tau in a Mouse Model of Alzheimer's Disease.
Alzheimer Disease
Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease.
Alzheimer Disease
Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases.
Alzheimer Disease
The Down-Regulation of Clusterin Expression Enhances the ?Synuclein Aggregation Process.
Alzheimer Disease
The Mitochondrial Hsp90 TRAP1 and Alzheimer's Disease.
Alzheimer Disease
The Molecular Chaperone GRP78/BiP as a Therapeutic Target for Neurodegenerative Disorders: A Mini Review.
Alzheimer Disease
The Synergistic Effects of Heat Shock Protein 70 and Ginsenoside Rg1 against Tert-Butyl Hydroperoxide Damage Model In Vitro.
Alzheimer Disease
The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease.
Alzheimer Disease
[Heat-shock protein HSP70 decreases activity of proteasomes in human neuroblastoma cells treated by amyloid-beta 1-42 with isomerized Asp7].
Amebiasis
A Novel C-Terminal Homologue of Aha1 Co-Chaperone Binds to Heat Shock Protein 90 and Stimulates Its ATPase Activity in Entamoeba histolytica.
Amebiasis
Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.
Amebiasis
Humoral immune response against a 70-kilodalton heat shock protein of Entamoeba histolytica in a group of patients with invasive amoebiasis.
Ameloblastoma
Immunohistochemical analysis of inducible nitric oxide synthase (iNOS) and heat shock proteins (HSPs) in ameloblastomas.
Ameloblastoma
Overexpression and extra-mitochondrial localization of the chaperonin Hsp60 in ameloblastoma.
Amyloidosis
Applying Hsp104 to protein-misfolding disorders.
Amyloidosis
Enhanced molecular chaperone activity of the small heat-shock protein ?B-crystallin following covalent immobilization onto a solid-phase support.
Amyloidosis
Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease.
Amyloidosis
Hsp104: a weapon to combat diverse neurodegenerative disorders.
Amyloidosis
Proteome analysis of cerebrospinal fluid in Guillain-Barré syndrome (GBS).
Amyotrophic Lateral Sclerosis
Acceleration of TDP43 and FUS/TLS protein expressions in the preconditioned hippocampus following repeated transient ischemia.
Amyotrophic Lateral Sclerosis
Administration of Recombinant Heat Shock Protein 70 Delays Peripheral Muscle Denervation in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis
Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Arimoclomol: a potential therapy under development for ALS.
Amyotrophic Lateral Sclerosis
Calcium-dependent protein folding in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Characterization and Hsp104-induced artificial clearance of familial ALS-related SOD1 aggregates.
Amyotrophic Lateral Sclerosis
Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice.
Amyotrophic Lateral Sclerosis
Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Expression of an endoplasmic reticulum-resident chaperone, glucose-regulated stress protein 78, in the spinal cord of a mouse model of amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1.
Amyotrophic Lateral Sclerosis
Mechanistic Insights into Hsp104 Potentiation.
Amyotrophic Lateral Sclerosis
Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.
Amyotrophic Lateral Sclerosis
Nitration of Hsp90 induces cell death.
Amyotrophic Lateral Sclerosis
Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.
Amyotrophic Lateral Sclerosis
Rapidly progressive amyotrophic lateral sclerosis is associated with microglial reactivity and small heat shock protein expression in reactive astrocytes.
Amyotrophic Lateral Sclerosis
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
Amyotrophic Lateral Sclerosis
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Amyotrophic Lateral Sclerosis
Ubiquitin and heat shock protein expression in amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Amyotrophic Lateral Sclerosis
[Effect of electroacupuncture on expression of heat shock protein 70 in mice with amyotrophic lateral sclerosis].
Anaphylaxis
Anaphylactic reaction induced by Toxoplasma gondii-derived heat shock protein 70.
Anaphylaxis
Protective immunity against lethal anaphylactic reaction in Toxoplasma gondii-infected mice by DNA vaccination with T. gondii-derived heat shock protein 70 gene.
Anaphylaxis
Toxoplasma gondii-derived heat shock protein 70 induces lethal anaphylactic reaction through activation of cytosolic phospholipase A2 and platelet-activating factor via Toll-like receptor 4/myeloid differentiation factor 88.
Anaplasmosis
Diverse tick-borne microorganisms identified in free-living ungulates in Slovakia.
Anemia
Changes in the expression of the heme-regulated eIF-2 alpha kinase and heat shock proteins in rabbit reticulocytes maturing during recovery from anemia.
Anemia
Dietary supplementation of brown seaweed (Sargassum latifolium) alleviates the environmental heat stress-induced toxicity in male Barki sheep (Ovis aries).
Anemia
HSP90 Shapes the Consequences of Human Genetic Variation.
Anemia
Molecular pathogenesis of myelodysplastic syndromes with deletion 5q.
Anemia
Responses of HSC70 expression in diencephalon to iron deficiency anemia in rats.
Anemia
Subcellular localization and interactions of Infectious Salmon Anemia Virus (ISAV) M1 and NEP as well as host Hsc70.
Anemia
Susceptibility of heat shock protein 70.1-deficient C57BL/6 J, wild-type C57BL/6 J and A/J mice to Trypanosoma congolense infection.
Anemia
The haem-regulated eukaryotic initiation factor 2alpha kinase: a molecular indicator of lead-toxicity anaemia in rabbits.
Anemia, Aplastic
High inducibility of heat shock protein 72 (hsp72) in peripheral blood mononuclear cells of aplastic anaemia patients: a reliable marker of immune-mediated aplastic anaemia responsive to cyclosporine therapy.
Anemia, Diamond-Blackfan
The severe phenotype of Diamond-Blackfan anemia is modulated by heat shock protein 70.
Anemia, Hypochromic
First Report of Tomato chlorosis virus Infecting Tomato Crops in Brazil.
Anemia, Hypochromic
Inactivation of the clpC1 gene encoding a chloroplast Hsp100 molecular chaperone causes growth retardation, leaf chlorosis, lower photosynthetic activity, and a specific reduction in photosystem content.
Anemia, Hypochromic
Inducible transgenic tobacco system to study the mechanisms underlying chlorosis mediated by the silencing of chloroplast heat shock protein 90.
Anemia, Hypochromic
Low Genetic Diversity Suggests a Single Introduction and Recent Spread of Tomato chlorosis virus in Brazil
Anemia, Iron-Deficiency
Responses of HSC70 expression in diencephalon to iron deficiency anemia in rats.
Anemia, Sickle Cell
Sickle cell vaso-occlusive crisis induces the release of circulating serum heat shock protein-70.
Anemia, Sideroblastic
Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9.
Aneurysm
Chronic ingestion of high dosed Phikud Navakot extraction induces mesangiolysis in rats with alteration of AQP1 and Hsp60 expressions.
Aneurysm, Dissecting
Heat shock protein 27 plays a protective role in thoracic aortic dissection by promoting cell proliferation and inhibiting apoptosis.
Aneurysm, Dissecting
HSP90 inhibitor 17-DMAG effectively alleviated the progress of thoracic aortic dissection by suppressing smooth muscle cell phenotypic switch.
Angina, Unstable
Chronic infections and histamine, CRP and IL-6 levels after percutaneous transluminal coronary angioplasty.
Angina, Unstable
Implications of antibodies to heat-shock proteins in ischemic heart disease.
Angina, Unstable
Serum levels of anti heat shock protein 70 antibodies in patients with stable and unstable angina pectoris.
Angina, Unstable
Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NFkappaB and AP-1.
Angina, Unstable
[Heat shock protein antibodies and other chlamydial antigens in various diseases and their occurrence in blood donors]
Angioedemas, Hereditary
Cytokine and estrogen stimulation of endothelial cells augments activation of the prekallikrein-high molecular weight kininogen complex: Implications for hereditary angioedema.
Angiofibroma
Identification of Heat Shock Protein 90 as a Recurrence Related Marker in Juvenile Nasopharyngeal Angiofibroma.
Anophthalmos
Hsp90 selectively modulates phenotype in vertebrate development.
Anthrax
GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore.
Anthrax
GroEL provides protection against Bacillus anthracis infection in BALB/c mice.
Anthrax
GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro.
Anthrax
Recombinant GroEL enhances protective antigen-mediated protection against Bacillus anthracis spore challenge.
Anthrax
Role of CypA and Hsp90 in membrane translocation mediated by anthrax Protective Antigen.
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Intense immunostaining of heat shock protein 70 within renal interstitium associates with long-term renal survival in an ANCA-associated vasculitis cohort.
Antiphospholipid Syndrome
Elevation of the 90 kDa heat-shock protein in specific subsets of systemic lupus erythematosus.
Anuria
Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal.
Aortic Aneurysm
Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve.
Aortic Aneurysm, Abdominal
Heat Shock Protein 90 Inhibition by 17-DMAG Attenuates Abdominal Aortic Aneurysm Formation in Mice.
Aortic Aneurysm, Abdominal
Plasma heat shock protein 27 is associated with coronary artery disease, abdominal aortic aneurysm and peripheral artery disease.
Aortic Aneurysm, Abdominal
Targeting HSP90 attenuates angiotensin II-induced adventitial remodeling via suppression of mitochondrial fission.
Aortic Valve Disease
Heat shock protein 90 is downregulated in calcific aortic valve disease.
Aortic Valve Stenosis
Heat shock protein 90 is downregulated in calcific aortic valve disease.
Apnea
Heat Shock Protein HSP70 in Oxidative Stress in Apnea Patients.
Appendicitis
[Content of antibodies to heat shock proteins in uncomplicated and complicated course of acute appendicitis].
Arrhythmogenic Right Ventricular Dysplasia
Proteomic analysis reveals significant elevation of heat shock protein 70 in patients with chronic heart failure due to arrhythmogenic right ventricular cardiomyopathy.
Arteriosclerosis
Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Arteriosclerosis
Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65.
Arteriosclerosis
Inhibition of arteriosclerosis by T-cell depletion in normocholesterolemic rabbits immunized with heat shock protein 65.
Arteriosclerosis Obliterans
Expression and clinical significance of HSP27 and its phosphorylation in lower extremity arteriosclerosis obliterans.
Arteriovenous Fistula
Serum osteoprotegerin level is associated with degree of arteriovenous fistula stenosis in patients with hemodialysis.
Arteritis
Serum levels of antibodies to Chlamydia pneumoniae and human HSP60 in giant cell arteritis patients.
Arthritis
A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis.
Arthritis
A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue.
Arthritis
A Humanized Monoclonal Antibody against Heat Shock Protein 60 Suppresses Murine Arthritis and Colitis and Skews the Cytokine Balance toward an Anti-Inflammatory Response.
Arthritis
A monoclonal antibody to the mycobacterial 65 kDa heat shock protein (ML 30) binds to cells in normal and arthritic joints of rats.
Arthritis
A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis.
Arthritis
Absence of peripheral blood T cell responses to "shared epitope' containing peptides in recent onset rheumatoid arthritis.
Arthritis
Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis.
Arthritis
An immunodominant epitope from mycobacterial 65-kDa heat shock protein protects against pristane-induced arthritis.
Arthritis
Anti-Hsp65 antibodies recognize M proteins of group A streptococci.
Arthritis
Antibodies against M. Bovis 65 KDa Heat Shock Protein and Its P180-188 Epitope in Sera of Patients with Juvenile Idiopathic Arthritis.
Arthritis
Antibodies to human HSP60 in patients with juvenile chronic arthritis, diabetes mellitus, and cystic fibrosis.
Arthritis
Antibodies to mycobacterial 65-kDa heat shock protein and other immunodominant antigens in patients with psoriasis.
Arthritis
Antibody response of restricted isotype to heat shock proteins in juvenile chronic arthritis.
Arthritis
Antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: epitope specificity and implication in pathogenesis.
Arthritis
Antimycobacterial hsp65 and rheumatoid factor titres in a population of normal twins: evidence of genetic control of rheumatoid factor.
Arthritis
Autoimmune reactions to heat-shock proteins in pristane-induced arthritis.
Arthritis
Autoreactivity to human heat-shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis.
Arthritis
Bystander suppression of experimental arthritis by nasal administration of a heat shock protein peptide.
Arthritis
CD4+ Th2 cells specific for mycobacterial 65-kilodalton heat shock protein protect against pristane-induced arthritis.
Arthritis
Cellular and humoral reactivity pattern to the mycobacterial heat shock protein hsp65 in pristane induced arthritis susceptible and hsp65 protected DBA/1 mice.
Arthritis
Characterization of the heat shock response and identification of heat shock protein antigens of Borrelia burgdorferi.
Arthritis
Comparison between the protective effects of mycobacterial 65-kD heat shock protein and ovomucoid in pristane-induced arthritis: relationship with agalactosyl IgG.
Arthritis
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes.
Arthritis
Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.
Arthritis
Environmental modulation of autoimmune arthritis involves the spontaneous microbial induction of T cell responses to regulatory determinants within heat shock protein 65.
Arthritis
Expression of mammalian 60-kD heat shock protein in the joints of mice with pristane-induced arthritis.
Arthritis
Frequency of anti-hsp60, -65 and -70 antibodies in sera of patients with juvenile idiopathic arthritis.
Arthritis
Gastric administration of recombinant 65 kDa heat shock protein delays the severity of type II collagen induced arthritis in mice.
Arthritis
Heat shock protein 60 and adjuvant arthritis: a model for T cell regulation in human arthritis.
Arthritis
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines.
Arthritis
Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?
Arthritis
Heat shock protein 65-reactive T cells are involved in the pathogenesis of non-antigenic dimethyl dioctadecyl ammonium bromide-induced arthritis.
Arthritis
Heat shock protein 70 membrane expression on fibroblast-like synovial cells derived from synovial tissue of patients with rheumatoid and juvenile idiopathic arthritis.
Arthritis
Heat shock protein expression is low in intestinal mucosa in juvenile idiopathic arthritis: a defect in immunoregulation?
Arthritis
Heat shock proteins as potential targets in the therapy of inflammatory arthritis.
Arthritis
Heat-shock proteins as immunogenic bacterial antigens with the potential to induce and regulate autoimmune arthritis.
Arthritis
Highly autoproliferative T cells specific for 60-kDa heat shock protein produce IL-4/IL-10 and IFN-gamma and are protective in adjuvant arthritis.
Arthritis
HSP60 Regulates Monosodium Urate Crystal-Induced Inflammation by Activating the TLR4-NF-?B-MyD88 Signaling Pathway and Disrupting Mitochondrial Function.
Arthritis
Humoral response against Mycobacterium bovis Hsp65 derived fragments in children and young people with various disorders.
Arthritis
IgG and IgA antibody titers against human heat-shock protein (hsp60) in sera of rheumatoid arthritis and osteoarthritis patients.
Arthritis
In Vitro and In Vivo Studies of the Biological Effects of Bioceramic (a Material of Emitting High Performance Far-Infrared Ray) Irradiation.
Arthritis
In vitro responses to a 65-kilodalton mycobacterial protein by synovial T cells from inflammatory arthritis patients.
Arthritis
Incidence of anti Hsp 90 and 70 antibodies in children with SLE, juvenile dermatomyositis and juvenile chronic arthritis.
Arthritis
Inhibition of adjuvant-induced arthritis by nasal administration of novel synthetic peptides from heat shock protein 65.
Arthritis
Juvenile chronic arthritis: T cell reactivity to human HSP60 in patients with a favorable course of arthritis.
Arthritis
Juvenile idiopathic arthritis and HSP60 vaccination: selective down-regulation?
Arthritis
Juvenile rheumatoid arthritis patients manifest immune reactivity to the mycobacterial 65-kDa heat shock protein, to its 180-188 peptide, and to a partially homologous peptide of the proteoglycan link protein.
Arthritis
Kruppel-like factor 2 (KLF2) regulates monocyte differentiation and functions in mBSA and IL-1?-induced arthritis.
Arthritis
Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein.
Arthritis
Mycobacterial heat shock protein 70 induces interleukin-10 production: immunomodulation of synovial cell cytokine profile and dendritic cell maturation.
Arthritis
Natural Withanolides in the Treatment of Chronic Diseases.
Arthritis
Oral administration of HSP-containing E. coli extract OM-89 has suppressive effects in autoimmunity. Regulation of autoimmune processes by modulating peripheral immunity towards hsp's?
Arthritis
Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis.
Arthritis
Peripheral blood mononuclear cell responses to heat shock proteins and their derived synthetic peptides in juvenile idiopathic arthritis patients.
Arthritis
Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein.
Arthritis
Protection of rats from adjuvant arthritis by immunization with naked DNA encoding for mycobacterial heat shock protein 65.
Arthritis
Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis.
Arthritis
Responses to gram negative enteric bacterial antigens by synovial T cells from patients with juvenile chronic arthritis: recognition of heat shock protein HSP60.
Arthritis
Role of endoplasmic reticulum stress in rheumatoid arthritis pathogenesis.
Arthritis
Self heat-shock protein 65-mediated regulation of autoimmune arthritis.
Arthritis
Serum heat shock protein 60 can predict remission of flare-up in juvenile idiopathic arthritis.
Arthritis
Specific immunity as a critical factor in the control of autoimmune arthritis: the example of hsp60 as an ancillary and protective autoantigen.
Arthritis
Stimulation of suppressive T cell responses by human but not bacterial 60-kD heat-shock protein in synovial fluid of patients with rheumatoid arthritis.
Arthritis
Stimulation of synovial fluid mononuclear cells with the human 65-kD heat shock protein or with live enterobacteria leads to preferential expansion of TCR-gamma delta+ lymphocytes.
Arthritis
Stress proteins are used by the immune system for cognate interactions with anti-inflammatory regulatory T cells.
Arthritis
Stress proteins, autoimmunity, and autoimmune disease.
Arthritis
Subcellular localization of the 65-kDa heat shock protein in mycobacteria by immunoblotting and immunogold ultracytochemistry.
Arthritis
Susceptibility to pristane-induced arthritis is altered with changes in bowel flora.
Arthritis
Synovial fluid T cell reactivity against 65 kD heat shock protein of mycobacteria in early chronic arthritis.
Arthritis
T-cell reactivity to human HSP60 in oligo-articular juvenile chronic arthritis is associated with a favorable prognosis and the generation of regulatory cytokines in the inflamed joint.
Arthritis
The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis.
Arthritis
The regulatory C-terminal determinants within mycobacterial heat shock protein 65 are cryptic and cross-reactive with the dominant self homologs: implications for the pathogenesis of autoimmune arthritis.
Arthritis
The role of heat shock protein in the persistence of arthritis.
Arthritis
Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis.
Arthritis
Three cases of arthritis after BCG therapy for bladder cancer.
Arthritis
TLR9 agonist CpG enhances protective nasal HSP60 peptide vaccine efficacy in experimental autoimmune arthritis.
Arthritis
Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis.
Arthritis
Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis.
Arthritis
V1.2. recognition of multiple hsp60 epitopes in patients with juvenile idiopathic arthritis opens the way for antigen-specific immunotherapy.
Arthritis
Vaccination with endosomal unknown epitopes produces therapeutic response in rheumatoid arthritis patients and modulates adjuvant arthritis of rats.
Arthritis
Yersinia-associated arthritis in rats: effect of 65 kDa heat shock protein, bovine serum albumin and incomplete Freund's adjuvant.
Arthritis, Experimental
A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue.
Arthritis, Experimental
A constitutive 65 kDa chondrocyte protein as a target antigen in adjuvant arthritis in Lewis rats.
Arthritis, Experimental
A Humanized Monoclonal Antibody against Heat Shock Protein 60 Suppresses Murine Arthritis and Colitis and Skews the Cytokine Balance toward an Anti-Inflammatory Response.
Arthritis, Experimental
A monoclonal antibody to the mycobacterial 65 kDa heat shock protein (ML 30) binds to cells in normal and arthritic joints of rats.
Arthritis, Experimental
A mycobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic.
Arthritis, Experimental
A self-hsp60 peptide acts as a partial agonist inducing expression of B7-2 on mycobacterial hsp60-specific T cells: a possible mechanism for inhibitory T cell regulation of adjuvant arthritis?
Arthritis, Experimental
A synthetic 10-kD heat shock protein (hsp10) from Mycobacterium tuberculosis modulates adjuvant arthritis.
Arthritis, Experimental
A synthetic mycobacterial heat shock peptide prevents adjuvant arthritis but not proteoglycan-induced synovitis in the rat.
Arthritis, Experimental
Activation of T cells recognizing an epitope of heat-shock protein 70 can protect against rat adjuvant arthritis.
Arthritis, Experimental
Adjuvant arthritis and immunity to the mycobacterial 65 kDa heat shock protein.
Arthritis, Experimental
Antibody levels to mycobacteria in relation to HLA type: evidence for non-HLA-linked high levels of antibody to the 65 kD heat shock protein of M. bovis in rheumatoid arthritis.
Arthritis, Experimental
Antibody reactivity to mycobacterial 65 kDa heat shock protein: relevance to autoimmunity.
Arthritis, Experimental
Cellular and humoral reactivity pattern to the mycobacterial heat shock protein HSP65 in adjuvant arthritis susceptible and resistant Wistar rats.
Arthritis, Experimental
Differential mycobacterial 65-kDa heat shock protein T cell epitope recognition after adjuvant arthritis-inducing or protective immunization protocols.
Arthritis, Experimental
Diversification of response to hsp65 during the course of autoimmune arthritis is regulatory rather than pathogenic.
Arthritis, Experimental
DNA fragments of the human 60-kDa heat shock protein (HSP60) vaccinate against adjuvant arthritis: identification of a regulatory HSP60 peptide.
Arthritis, Experimental
Generation and characterization of a clonotypic antibody specific for the T cell receptor of an arthritogenic T cell clone--studies in adjuvant arthritis.
Arthritis, Experimental
Highly autoproliferative T cells specific for 60-kDa heat shock protein produce IL-4/IL-10 and IFN-gamma and are protective in adjuvant arthritis.
Arthritis, Experimental
Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60.
Arthritis, Experimental
Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein.
Arthritis, Experimental
Natural antibodies to 65 kD mycobacterial heat shock protein in rats do not correlate with susceptibility for Mycobacterium tuberculosis induced adjuvant arthritis.
Arthritis, Experimental
Prevention of adjuvant arthritis in rats by a nonapeptide from the 65-kD mycobacterial heat shock protein: specificity and mechanism.
Arthritis, Experimental
Preventive administration of Mycobacterium tuberculosis 10-kDa heat shock protein (hsp10) suppresses adjuvant arthritis in Lewis rats.
Arthritis, Experimental
Protection of rats from adjuvant arthritis by immunization with naked DNA encoding for mycobacterial heat shock protein 65.
Arthritis, Experimental
Resistance to adjuvant arthritis is due to protective antibodies against heat shock protein surface epitopes and the induction of IL-10 secretion.
Arthritis, Experimental
Significance of endogenous heat shock protein in adjuvant arthritis.
Arthritis, Experimental
Strain differences and the role for HSP47 and HSP70 in adjuvant arthritis in rats.
Arthritis, Experimental
Suppression of adjuvant arthritis in rats by induction of oral tolerance to mycobacterial 65-kDa heat shock protein.
Arthritis, Experimental
Susceptibility and resistance to experimental adjuvant arthritis.
Arthritis, Experimental
T cell responses to conserved bacterial heat-shock-protein epitopes induce resistance in experimental autoimmunity.
Arthritis, Experimental
T-cell response to self HSP60 peptides in renal transplant recipients: a regulatory role?
Arthritis, Experimental
The beta 2-adrenergic agonist salbutamol potentiates oral induction of tolerance, suppressing adjuvant arthritis and antigen-specific immunity.
Arthritis, Experimental
The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challenge.
Arthritis, Experimental
The possible role of heat shock protein-70 induction in collagen-induced arthritis in rats.
Arthritis, Experimental
The regulatory C-terminal determinants within mycobacterial heat shock protein 65 are cryptic and cross-reactive with the dominant self homologs: implications for the pathogenesis of autoimmune arthritis.
Arthritis, Experimental
Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis.
Arthritis, Experimental
Towards peptide immunotherapy in rheumatoid arthritis: competitor-modulator concept.
Arthritis, Experimental
Treatment of adjuvant arthritis in rats: vaccination potential of a synthetic nonapeptide from the 65 kDa heat shock protein of mycobacteria.
Arthritis, Experimental
Treatment of adjuvant arthritis with granulocyte-colony stimulating factor and peptide derived from heat shock protein 65.
Arthritis, Gouty
Capillary Electrophoresis with Laser Induced Fluorescence Detection for Study of the Association of HSP60 Gene Polymorphism with Gouty Arthritis.
Arthritis, Juvenile
Antibodies against M. Bovis 65 KDa Heat Shock Protein and Its P180-188 Epitope in Sera of Patients with Juvenile Idiopathic Arthritis.
Arthritis, Juvenile
Antibodies to human HSP60 in patients with juvenile chronic arthritis, diabetes mellitus, and cystic fibrosis.
Arthritis, Juvenile
Antibody response of restricted isotype to heat shock proteins in juvenile chronic arthritis.
Arthritis, Juvenile
Autoreactivity to human heat-shock protein 60 predicts disease remission in oligoarticular juvenile rheumatoid arthritis.
Arthritis, Juvenile
Frequency of anti-hsp60, -65 and -70 antibodies in sera of patients with juvenile idiopathic arthritis.
Arthritis, Juvenile
Heat shock protein 70 membrane expression on fibroblast-like synovial cells derived from synovial tissue of patients with rheumatoid and juvenile idiopathic arthritis.
Arthritis, Juvenile
Heat shock protein expression is low in intestinal mucosa in juvenile idiopathic arthritis: a defect in immunoregulation?
Arthritis, Juvenile
Heat-shock proteins as immunogenic bacterial antigens with the potential to induce and regulate autoimmune arthritis.
Arthritis, Juvenile
Humoral response against Mycobacterium bovis Hsp65 derived fragments in children and young people with various disorders.
Arthritis, Juvenile
Immune responses to the Escherichia coli dnaJ heat shock protein in juvenile rheumatoid arthritis and their correlation with disease activity.
Arthritis, Juvenile
Incidence of anti Hsp 90 and 70 antibodies in children with SLE, juvenile dermatomyositis and juvenile chronic arthritis.
Arthritis, Juvenile
Juvenile chronic arthritis: T cell reactivity to human HSP60 in patients with a favorable course of arthritis.
Arthritis, Juvenile
Juvenile idiopathic arthritis and HSP60 vaccination: selective down-regulation?
Arthritis, Juvenile
Juvenile rheumatoid arthritis patients manifest immune reactivity to the mycobacterial 65-kDa heat shock protein, to its 180-188 peptide, and to a partially homologous peptide of the proteoglycan link protein.
Arthritis, Juvenile
Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis.
Arthritis, Juvenile
Responses to gram negative enteric bacterial antigens by synovial T cells from patients with juvenile chronic arthritis: recognition of heat shock protein HSP60.
Arthritis, Juvenile
Self heat-shock protein 65-mediated regulation of autoimmune arthritis.
Arthritis, Juvenile
Serum heat shock protein 60 can predict remission of flare-up in juvenile idiopathic arthritis.
Arthritis, Juvenile
T-cell reactivity to human HSP60 in oligo-articular juvenile chronic arthritis is associated with a favorable prognosis and the generation of regulatory cytokines in the inflamed joint.
Arthritis, Juvenile
Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis.
Arthritis, Juvenile
Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis.
Arthritis, Juvenile
V1.2. recognition of multiple hsp60 epitopes in patients with juvenile idiopathic arthritis opens the way for antigen-specific immunotherapy.
Arthritis, Psoriatic
Autoantibodies to human stress proteins. A survey of various rheumatic and other inflammatory diseases.
Arthritis, Reactive
A single nonamer from the Yersinia 60-kDa heat shock protein is the target of HLA-B27-restricted CTL response in Yersinia-induced reactive arthritis.
Arthritis, Reactive
Autoantibodies to human heat shock protein (hsp)60 may be induced by Escherichia coli groEL.
Arthritis, Reactive
Identification and characterization of a DR4-restricted T cell epitope within chlamydia heat shock protein 60.
Arthritis, Reactive
In vitro responses to a 65-kilodalton mycobacterial protein by synovial T cells from inflammatory arthritis patients.
Arthritis, Reactive
Induction of abnormal Chlamydia trachomatis by exposure to interferon-gamma or amino acid deprivation and comparative antigenic analysis.
Arthritis, Reactive
Responses to gram negative enteric bacterial antigens by synovial T cells from patients with juvenile chronic arthritis: recognition of heat shock protein HSP60.
Arthritis, Reactive
Serum antibodies from patients with ankylosing spondylitis and Reiter's syndrome are reactive with HLA-B27 cells transfected with the Mycobacterium tuberculosis hsp60 gene.
Arthritis, Reactive
The humoral immune response to Chlamydia trachomatis in patients with acute reactive arthritis.
Arthritis, Rheumatoid
A dominant human leucocyte antigen DR4-Dw15 restricted mycobacterial 65 kDa antigen-specific T-cell immunity in Chinese patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Aberrant extracellular and dendritic cell (DC) surface expression of heat shock protein (hsp)70 in the rheumatoid joint: possible mechanisms of hsp/DC-mediated cross-priming.
Arthritis, Rheumatoid
Agalactosyl IgG, antibodies to heat shock proteins, and acute rheumatic fever.
Arthritis, Rheumatoid
Analysis of 70Kd heat shock protein expression in patients with internal derangement of the temporomandibular joint.
Arthritis, Rheumatoid
Analysis of human 65 kD heat shock protein mRNA using polymerase chain reaction in synovia of rheumatoid arthritis patients.
Arthritis, Rheumatoid
Analysis of serum heat shock protein 70 (HSPA1A) concentrations for diagnosis and disease activity monitoring in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Antibodies against human 60 kDa heat shock protein are not associated with cardiovascular disease in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Antibodies to heat shock protein 65 kD in type 1 diabetes mellitus.
Arthritis, Rheumatoid
Antibodies to mycobacterial 65 kDa heat shock protein in systemic sclerosis (scleroderma).
Arthritis, Rheumatoid
Antibodies to the constitutive 73-kd heat shock protein: a new marker of mixed connective tissue disease?
Arthritis, Rheumatoid
Antibody levels to mycobacteria in relation to HLA type: evidence for non-HLA-linked high levels of antibody to the 65 kD heat shock protein of M. bovis in rheumatoid arthritis.
Arthritis, Rheumatoid
Antibody reactivity to mycobacterial 65 kDa heat shock protein: relevance to autoimmunity.
Arthritis, Rheumatoid
Antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: epitope specificity and implication in pathogenesis.
Arthritis, Rheumatoid
Antibody to Mycobacterium tuberculosis 65 kDa heat shock protein in patients with rheumatoid arthritis--a survey of antigen-specific antibody isotypes and subclasses in an endemic area of previous tuberculosis infection.
Arthritis, Rheumatoid
Association between the 65-kilodalton heat shock protein, Streptococcus sanguis, and the corresponding antibodies in Behçet's syndrome.
Arthritis, Rheumatoid
Association of stress proteins with autoantigens: a possible mechanism for triggering autoimmunity?
Arthritis, Rheumatoid
Autoantibodies against chaperonin CCT in human sera with rheumatic autoimmune diseases: comparison with antibodies against other Hsp60 family proteins.
Arthritis, Rheumatoid
Autoantibodies to human heat shock protein (hsp)60 may be induced by Escherichia coli groEL.
Arthritis, Rheumatoid
Autoantigen BiP and autoimmune diseases.
Arthritis, Rheumatoid
Autoreactive T cells to citrullinated HSP90 are associated with interstitial lung disease in rheumatoid arthritis.
Arthritis, Rheumatoid
BiP, a putative autoantigen in rheumatoid arthritis, stimulates IL-10-producing CD8-positive T cells from normal individuals.
Arthritis, Rheumatoid
Cellular immune response to Klebsiella pneumoniae antigens in patients with HLA-B27+ ankylosing spondylitis.
Arthritis, Rheumatoid
Chemical inhibition of HSP90 inhibits TNF-? mediated proliferation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes.
Arthritis, Rheumatoid
Continuous enhanced expression of Hsc70 but not Hsp70 in rheumatoid arthritis synovial tissue.
Arthritis, Rheumatoid
Detection of autoantibodies to the pancreatic islet heat shock protein 60 in insulin-dependent diabetes mellitus.
Arthritis, Rheumatoid
Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis.
Arthritis, Rheumatoid
Effect of sulphasalazine on gastrointestinal microflora and on mucosal heat shock protein expression in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs.
Arthritis, Rheumatoid
Epitope specificity and MHC restriction of rheumatoid arthritis synovial T cell clones which recognize a mycobacterial 65 kDa heat shock protein.
Arthritis, Rheumatoid
Experimental immunization with anti-rheumatic bacterial extract OM-89 induces T cell responses to heat shock protein (hsp)60 and hsp70; modulation of peripheral immunological tolerance as its possible mode of action in the treatment of rheumatoid arthritis (RA).
Arthritis, Rheumatoid
Expression of heat shock protein on lymphocytes in peripheral blood and synovial fluid from patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Expression of heat-shock proteins in Streptococcus pyogenes and their immunoreactivity with sera from patients with streptococcal diseases.
Arthritis, Rheumatoid
Expression of mammalian 60-kD heat shock protein in the joints of mice with pristane-induced arthritis.
Arthritis, Rheumatoid
Extensive Citrullination Promotes Immunogenicity of HSP90 through Protein Unfolding and Exposure of Cryptic Epitopes.
Arthritis, Rheumatoid
Geranylgeranylacetone, a non-toxic inducer of heat shock protein, induces cell death in fibroblast-like synoviocytes from patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Heat shock protein 70 gene polymorphisms in rheumatoid arthritis.
Arthritis, Rheumatoid
Heat shock protein 70 membrane expression on fibroblast-like synovial cells derived from synovial tissue of patients with rheumatoid and juvenile idiopathic arthritis.
Arthritis, Rheumatoid
Heat shock protein 90 is required for increased DNA binding activity of activator protein-1, a heterodimer of Fos/JunD, in rheumatoid synovial cells under inflammatory stimuli.
Arthritis, Rheumatoid
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Arthritis, Rheumatoid
Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling.
Arthritis, Rheumatoid
Heat shock protein gene expression profile may differentiate between rheumatoid arthritis, osteoarthritis, and healthy controls.
Arthritis, Rheumatoid
Hsp40 proteins modulate humoral and cellular immune response in rheumatoid arthritis patients.
Arthritis, Rheumatoid
Hsp60 and Hsp10 as Antitumor Molecular Agents.
Arthritis, Rheumatoid
HSP70-1 promoter region alleles and susceptibility to rheumatoid arthritis.
Arthritis, Rheumatoid
Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis.
Arthritis, Rheumatoid
Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis.
Arthritis, Rheumatoid
Immune responses to Mycobacterial heat shock protein 70 accompany self-reactivity to human BiP in rheumatoid arthritis.
Arthritis, Rheumatoid
Immunodominant region of Actinobacillus actinomycetemcomitans 40-kilodalton heat shock protein in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
In-vitro effects of Mycobacterium bovis BCG-lysate and its derived heat shock proteins on cytokines secretion by blood mononuclear cells of rheumatoid arthritis patients in comparison with healthy controls.
Arthritis, Rheumatoid
Induction of human hsp60 expression in monocytic cell lines.
Arthritis, Rheumatoid
Inhibition of antigen-presenting cell function and stimulation of human peripheral blood mononuclear cells to express an antiinflammatory cytokine profile by the stress protein BiP: relevance to the treatment of inflammatory arthritis.
Arthritis, Rheumatoid
Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70.
Arthritis, Rheumatoid
Interference by IgM rheumatoid factor on ELISA for antibodies to mycobacterial 65 kDa heat shock protein in rheumatoid arthritis.
Arthritis, Rheumatoid
Is Male Rheumatoid Arthritis an Occupational Disease? A Review.
Arthritis, Rheumatoid
Major differences in antigen-processing correlate with a single Arg71<-->Lys substitution in HLA-DR molecules predisposing to rheumatoid arthritis and with their selective interactions with 70-kDa heat shock protein chaperones.
Arthritis, Rheumatoid
New perspective on Behçet's disease.
Arthritis, Rheumatoid
Pan-DR-binding Hsp60 self epitopes induce an interleukin-10-mediated immune response in rheumatoid arthritis.
Arthritis, Rheumatoid
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Arthritis, Rheumatoid
Preferential binding with Escherichia coli hsp60 of antibodies prevalent in sera from patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Presence of human 65 kD heat shock protein (hsp) in inflamed joints and subcutaneous nodules of RA patients.
Arthritis, Rheumatoid
Proliferative response of synovial fluid mononuclear cells of patients with rheumatoid arthritis to mycobacterial 65 kDa heat shock protein and its association with HLA-DR+.gamma delta+ T cells.
Arthritis, Rheumatoid
Protein moonlighting: a new factor in biology and medicine.
Arthritis, Rheumatoid
Purification of recombinant human Hsp60: use of a GroEL-free preparation to assess autoimmunity in rheumatoid arthritis.
Arthritis, Rheumatoid
Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis.
Arthritis, Rheumatoid
Sequence homologies between hsp60 and autoantigens.
Arthritis, Rheumatoid
Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis.
Arthritis, Rheumatoid
Stimulatory response towards the 65 kDa heat shock protein and other mycobacterial antigens in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
T cell response to human HSP60 and yersinia 19 kDa in ankylosing spondylitis and rheumatoid arthritis: no evidence for a causal role of these antigens in the pathogenesis.
Arthritis, Rheumatoid
The B cell repertoire of patients with rheumatoid arthritis. Frequencies and specificities of peripheral blood B cells reacting with human IgG, human collagens, a mycobacterial heat shock protein and other antigens.
Arthritis, Rheumatoid
The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis.
Arthritis, Rheumatoid
The regulatory C-terminal determinants within mycobacterial heat shock protein 65 are cryptic and cross-reactive with the dominant self homologs: implications for the pathogenesis of autoimmune arthritis.
Arthritis, Rheumatoid
The susceptibility sequence to rheumatoid arthritis is a cross-reactive B cell epitope shared by the Escherichia coli heat shock protein dnaJ and the histocompatibility leukocyte antigen DRB10401 molecule.
Arthritis, Rheumatoid
Treatment with Recombinant Hsp72 Suppresses Collagen-Induced Arthritis in Mice.
Arthritis, Rheumatoid
Tripterine prevents endothelial barrier dysfunction by inhibiting endogenous peroxynitrite formation.
Arthritis, Rheumatoid
TXNDC5 synergizes with HSC70 to exacerbate the inflammatory phenotype of synovial fibroblasts in rheumatoid arthritis through NF-?B signaling.
Arthritis, Rheumatoid
[Autoimmune diseases and stress proteins]
Arthritis, Rheumatoid
[Research for basic and clinical aspects of Behcet's disease--recent advance and future--]
Arthritis, Rheumatoid
[The effect of Hsp72 on IL-6, IL-8 expression and activation of NF-kappaB in synoviocytes of rheumatoid arthritis].
Aspergillosis
COVID19 associated mucormycosis: Is GRP78 a possible link?
Aspergillosis
Heat shock protein 88 and Aspergillus infection.
Aspergillosis
Heat shock protein 90 (Hsp90): A novel antifungal target against Aspergillus fumigatus.
Aspergillosis
Identification of a Key Lysine Residue in Heat Shock Protein 90 Required for Azole and Echinocandin Resistance in Aspergillus fumigatus.
Aspergillosis
In vitro and in vivo role of heat shock protein 90 in Amphotericin B resistance of Aspergillus terreus.
Aspergillosis
Newer combination antifungal therapies for invasive aspergillosis.
Aspergillosis
Transcriptional Activation of Heat-Shock Protein 90 (Hsp90) Mediated Via a Proximal Promoter Region Confers Caspofungin Resistance in Aspergillus fumigatus.
Asthenozoospermia
Association of GRP78 promoter polymorphisms and serum GRP78 level with risk of asthenozoospermia.
Asthenozoospermia
Membrane bound Glucose Regulated Protein 78 interacts with alpha-2-macroglobulin to promote actin reorganization in sperm during epididymal maturation.
Asthenozoospermia
[Asthenozoospermia is not correlated with 3' UTR polymorphisms of the GRP78 gene].
Asthma
Active Ingredients of Epimedii Folium and Ligustri Lucidi Fructus Balanced GR/HSP90 to Improve the Sensitivity of Asthmatic Rats to Budesonide.
Asthma
Airflow limitation, asthma, and Chlamydia pneumoniae-specific heat shock protein 60.
Asthma
Alveolar macrophages in allergic asthma: an expression signature characterized by heat shock protein pathways.
Asthma
An imbalance in antioxidant enzymes and stress proteins in childhood asthma.
Asthma
An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling.
Asthma
Bronchial gamma delta T-lymphocytes and expression of heat shock proteins in mild asthma.
Asthma
Chlamydia pneumoniae and severity of asthma.
Asthma
Cross talk between Hsp72, HMGB1 and RAGE/ERK1/2 signaling in the pathogenesis of bronchial asthma in obese patients.
Asthma
Decreased expression of heat shock protein 20 in colorectal cancer and its implication in tumorigenesis.
Asthma
Differential DAMP release was observed in the sputum of COPD, asthma and asthma-COPD overlap (ACO) patients.
Asthma
Erratum to: Increased heat shock protein 70 levels in induced sputum and plasma correlate with severity of asthma patients.
Asthma
Heat shock protein 70 gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease.
Asthma
Heat shock protein 70 upregulation is related to HLA-DR expression in bronchial asthma. Effects of inhaled glucocorticoids.
Asthma
Heat shock protein X purified from Mycobacterium tuberculosis enhances the efficacy of dendritic cells-based immunotherapy for the treatment of allergic asthma.
Asthma
Heat shock proteins mRNA expressions by peripheral blood mononuclear cells in asthma and chronic bronchitis.
Asthma
Host immune response to Chlamydia pneumoniae heat shock protein 60 is associated with asthma.
Asthma
Increased expression of heat shock protein 70 on airway cells in asthma and chronic bronchitis.
Asthma
Increased heat shock protein 70 levels in induced sputum and plasma correlate with severity of asthma patients.
Asthma
Modification of lung endoplasmic reticulum genes expression and NF-kB protein levels in obese ovalbumin-sensitized male and female rats.
Asthma
Nitric oxide suppresses LPS-induced inflammation in a mouse asthma model by attenuating the interaction of IKK and Hsp90.
Asthma
Oral administration of Hsp65-producing Lactococcus lactis attenuates allergic asthma in a murine model.
Asthma
Plasma antibodies against heat shock protein 70 correlate with the incidence and severity of asthma in a Chinese population.
Asthma
Regulation of CD23 in the chronic inflammatory response in asthma: a role for interferon-gamma and heat shock protein 70 in the TH2 environment.
Asthma
The influence of dexamethasone and the role of some antioxidant vitamins in the pathogenesis of experimental bronchial asthma.
Asthma
The Protective Effects of Helicobacter pylori Infection on Allergic Asthma.
Asthma
The Role of Heat Shock Protein 70 kDa in Asthma.
Astrocytoma
AP-1 and heat shock protein 27 expression in human astrocytomas.
Astrocytoma
Association of elevated GRP78 expression with increased astrocytoma malignancy via Akt and ERK pathways.
Astrocytoma
Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines.
Astrocytoma
Dynamic O-GlcNAcylation of the small heat shock protein alpha B-crystallin.
Astrocytoma
Expression of the small heat shock protein (hsp) 27 in human astrocytomas correlates with histologic grades and tumor growth fractions.
Astrocytoma
Heat shock protein expression in human gliomas.
Astrocytoma
HIV-1 Gp120 clade B/C induces a GRP78 driven cytoprotective mechanism in astrocytoma.
Astrocytoma
Integrated proteomic platforms for the comparative characterization of medulloblastoma and pilocytic astrocytoma pediatric brain tumors: a preliminary study.
Astrocytoma
NO-induced downregulation of HSP10 and HSP60 expression in the postischemic brain.
Astrocytoma
Phosphorylated Hsp27 is mutually exclusive with ATRX loss and the IDH1
Astrocytoma
Potential biomarkers of childhood brain tumor identified by proteomics of cerebrospinal fluid from extraventricular drainage (EVD).
Astrocytoma
The stress kit: a new method based on competitive reverse transcriptase-polymerase chain reaction to quantify the expression of human alphaB-crystallin, Hsp27, and Hsp60.
Astrocytoma
The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor.
Asymptomatic Infections
Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis.
Asymptomatic Infections
Expression of the 60 kDa heat shock protein in peritoneal fluids from women with endometriosis: implications for endometriosis-associated infertility.
Ataxia
Response of cell cycle/stress-related protein expression and DNA damage upon treatment of CaCo2 cells with anthocyanins.
Ataxia
The neurodegenerative-disease-related protein sacsin is a molecular chaperone.
Ataxia Telangiectasia
Activation of eNOS in endothelial cells exposed to ionizing radiation involves components of the DNA damage response pathway.
Ataxia Telangiectasia
Chronic hypoxia in Andeans; are there lessons for neurology at sea level?
Ataxia Telangiectasia
Confirmation that variants in TTI2 are responsible for autosomal recessive intellectual disability.
Ataxia Telangiectasia
Cooperative Enhancement of Radiosensitivity After Combined Treatment of 17-(Allylamino)-17-Demethoxygeldanamycin and Celecoxib in Human Lung and Colon Cancer Cell Lines.
Ataxia Telangiectasia
Differential Expression of Small Heat Shock Protein 27 (Hsp27) in Ataxia telangiectasia Brains.
Ataxia Telangiectasia
Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells.
Ataxia Telangiectasia
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status.
Ataxia Telangiectasia
Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription.
Ataxia Telangiectasia
Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion.
Ataxia Telangiectasia
Temporal changes in mouse aortic wall gene expression during the development of elastase-induced abdominal aortic aneurysms.
Atherosclerosis
A new murine model for atherosclerosis with inflammation in the periodontal tissue induced by immunization with heat shock protein 60.
Atherosclerosis
A novel atherogenic epitope from Mycobacterium tuberculosis heat shock protein 65 enhances atherosclerosis in rabbit and LDL receptor-deficient mice.
Atherosclerosis
A physiologically relevant atherogenic diet causes severe endothelial dysfunction within 4 weeks in rabbit.
Atherosclerosis
A Th2 immune shift to heat shock protein 65 fails to arrest atherosclerosis: Proatherogenic role of Th2-deviated autoantibodies.
Atherosclerosis
Anti-heat shock protein 60 autoantibodies induce atherosclerosis in apolipoprotein E-deficient mice via endothelial damage.
Atherosclerosis
Anti-heat shock protein 70 autoantibody epitope changes and BD091 promotes atherosclerosis in rats.
Atherosclerosis
Anti-HSP60 Immunity Is Already Associated with Atherosclerosis Early in Life.
Atherosclerosis
ApoB-100 and HSP60 Peptides Exert a Synergetic Role in Inhibiting Early Atherosclerosis in Immunized ApoE-null Mice.
Atherosclerosis
Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk.
Atherosclerosis
Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study.
Atherosclerosis
Atherosclerosis and connective tissue diseases.
Atherosclerosis
Atherosclerosis as a paradigmatic disease of the elderly: role of the immune system.
Atherosclerosis
Atherosclerosis--an autoimmune disease due to an immune reaction against heat-shock protein 60.
Atherosclerosis
Atherosclerotic lesion development and Toll like receptor 2 and 4 responsiveness.
Atherosclerosis
Atorvastatin downregulates HSP22 expression in an atherosclerotic model in vitro and in vivo.
Atherosclerosis
Atorvastatin inhibits CD68 expression in aortic root through a GRP78-involved pathway.
Atherosclerosis
Autoantibodies against heat shock protein 60 mediate endothelial cytotoxicity.
Atherosclerosis
Autoimmune and inflammatory mechanisms in atherosclerosis.
Atherosclerosis
Autoreactive HSP60 epitope-specific T-cells in early human atherosclerotic lesions.
Atherosclerosis
Beta-actin: a regulator of NOS-3.
Atherosclerosis
Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27.
Atherosclerosis
Cellular and humoral immune responses to heat shock protein 65 are both involved in promoting fatty-streak formation in LDL-receptor deficient mice.
Atherosclerosis
Changes in heat shock protein 70 localization and its content in rabbit aorta at various stages of experimental atherosclerosis.
Atherosclerosis
Characterization of a natural mouse monoclonal antibody recognizing epitopes shared by oxidized low-density lipoprotein and chaperonin 60 of Aggregatibacter actinomycetemcomitans.
Atherosclerosis
Characterization of HSP27 phosphorylation sites in human atherosclerotic plaque secretome.
Atherosclerosis
Characterization of human anti-heat shock protein 60 monoclonal autoantibody Fab fragments in atherosclerosis: Genetic and functional analysis.
Atherosclerosis
Chlamydia pneumoniae heat shock protein 60 enhances expression of ERK, TLR-4 and IL-8 in atheromatous plaques of coronary artery disease patients.
Atherosclerosis
Chlamydia pneumoniae infection acts as an endothelial stressor with the potential to initiate the earliest heat shock protein 60-dependent inflammatory stage of atherosclerosis.
Atherosclerosis
Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages.
Atherosclerosis
Chronic over-expression of heat shock protein 27 attenuates atherogenesis and enhances plaque remodeling: a combined histological and mechanical assessment of aortic lesions.
Atherosclerosis
Circulating heat shock protein 27 as a novel marker of subclinical atherosclerosis in type 2 diabetes: a cross-sectional community-based study.
Atherosclerosis
Circulating heat shock protein 60 is associated with early cardiovascular disease.
Atherosclerosis
Circulating heat shock protein and heat shock protein antibody levels in established hypertension.
Atherosclerosis
Co-expression of ICAM-1, VCAM-1, ELAM-1 and Hsp60 in human arterial and venous endothelial cells in response to cytokines and oxidized low-density lipoproteins.
Atherosclerosis
Cooling the Fire of Atherosclerosis with Heat Shock Protein 27.
Atherosclerosis
Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis.
Atherosclerosis
Cross-reactivity of GroEL antibodies with human heat shock protein 60 and quantification of pathogens in atherosclerosis.
Atherosclerosis
Detection of HSP60 on the membrane surface of stressed human endothelial cells by atomic force and confocal microscopy.
Atherosclerosis
Diet-induced elevation of circulating HSP70 may trigger cell adhesion and promote the development of atherosclerosis in rats.
Atherosclerosis
Differential distribution of 70-kD heat shock protein in atherosclerosis. Its potential role in arterial SMC survival.
Atherosclerosis
Differentially expressed soluble proteins in aortic cells from atherosclerosis-susceptible and resistant pigeons.
Atherosclerosis
Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?
Atherosclerosis
Down-regulation of hsa-miR-148b inhibits vascular smooth muscle cells proliferation and migration by directly targeting HSP90 in atherosclerosis.
Atherosclerosis
Effect of dyslipidemia on intima-media thickness of intra- and extracranial atherosclerosis by regulating the expression of hsp70 in rabbits.
Atherosclerosis
Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: establishment of a combined model and association with heat shock protein 65 immunity.
Atherosclerosis
Effects of oral and subcutaneous administration of HSP60 on myeloid-derived suppressor cells and atherosclerosis in ApoE-/- mice.
Atherosclerosis
Endothelial cytotoxicity mediated by serum antibodies to heat shock proteins of Escherichia coli and Chlamydia pneumoniae: immune reactions to heat shock proteins as a possible link between infection and atherosclerosis.
Atherosclerosis
Endothelial TNF-? induction by Hsp60 secreted from THP-1 monocytes exposed to hyperglycaemic conditions.
Atherosclerosis
Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents.
Atherosclerosis
Epitope mapping of Porphyromonas gingivalis heat-shock protein and human heat-shock protein in human atherosclerosis.
Atherosclerosis
Establishment of nasal tolerance to heat shock protein-60 alleviates atherosclerosis by inducing TGF-?-dependent regulatory T cells.
Atherosclerosis
Expression levels of heat shock protein 60 in human endothelial cells in vitro are unaffected by exposure to 50 Hz magnetic fields.
Atherosclerosis
Expression of heat shock protein-70 by dendritic cells in the arterial intima and its potential significance in atherogenesis.
Atherosclerosis
Extracellular HSP27 acts as a signaling molecule to activate NF-?B in macrophages.
Atherosclerosis
Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A.
Atherosclerosis
Fusobacterium nucleatum GroEL induces risk factors of atherosclerosis in human microvascular endothelial cells and ApoE(-/-) mice.
Atherosclerosis
Genetic variations of HSPA1A, the heat shock protein levels, and risk of atherosclerosis.
Atherosclerosis
GroEL1, a Heat Shock Protein 60 of Chlamydia pneumoniae, Induces Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Expression in Endothelial Cells and Enhances Atherogenesis in Hypercholesterolemic Rabbits.
Atherosclerosis
Heat Shock Protein 27 Protects Against Atherogenesis via an Estrogen-Dependent Mechanism. Role of Selective Estrogen Receptor Beta Modulation.
Atherosclerosis
Heat shock protein 27-derived atheroprotection involves reverse cholesterol transport that is dependent on GM-CSF to maintain ABCA1 and ABCG1 expression in ApoE
Atherosclerosis
Heat shock protein 60 and immune inflammatory responses in atherosclerosis.
Atherosclerosis
Heat Shock Protein 60 in Cardiovascular Physiology and Diseases.
Atherosclerosis
Heat shock protein 60 involvement in vascular smooth muscle cell proliferation.
Atherosclerosis
Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein.
Atherosclerosis
Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation.
Atherosclerosis
Heat shock protein 60/65, beta 2-glycoprotein I and oxidized LDL as players in murine atherosclerosis.
Atherosclerosis
Heat shock protein 65 promotes atherosclerosis through impairing the properties of high density lipoprotein.
Atherosclerosis
Heat shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway.
Atherosclerosis
Heat shock protein 70 and antibodies to heat shock protein 60 are associated with cerebrovascular atherosclerosis.
Atherosclerosis
Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis.
Atherosclerosis
Heat Shock Proteins: Mediators of Atherosclerotic Development.
Atherosclerosis
Heat-shock protein 90: A novel autoantigen in human carotid atherosclerosis.
Atherosclerosis
Helicobacter pylori and cardiovascular complications: a mechanism based review on role of Helicobacter pylori in cardiovascular diseases.
Atherosclerosis
Helicobacter pylori and cardiovascular disease: update 2019.
Atherosclerosis
Hemolymph transcriptome analysis of Chinese mitten crab (Eriocheir sinensis) with intact, left cheliped autotomy and bilateral eyestalk ablation.
Atherosclerosis
High dietary methionine plus cholesterol stimulates early atherosclerosis and late fibrous cap development which is associated with a decrease in GRP78 positive plaque cells.
Atherosclerosis
Hormone replacement therapy increases levels of antibodies against heat shock protein 65 and certain species of oxidized low density lipoprotein.
Atherosclerosis
HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production and Mitochondrial Caspase-Dependent Apoptotic Pathway.
Atherosclerosis
Hsp27 promotes ABCA1 expression and cholesterol efflux through the PI3K/PKC?/Sp1 pathway in THP-1 macrophages.
Atherosclerosis
Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins.
Atherosclerosis
HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis.
Atherosclerosis
HSP90 inhibition suppresses inflammatory response and reduces carotid atherosclerotic plaque formation in ApoE mice.
Atherosclerosis
HSP90 inhibitors as a future therapeutic strategy in diabetes-driven atherosclerosis.
Atherosclerosis
Humoral immune response to heat shock protein 60 of Aggregatibacter actinomycetemcomitans and cross-reactivity with malondialdehyde acetaldehyde-modified LDL.
Atherosclerosis
Identification by a differential proteomic approach of heat shock protein 27 as a potential marker of atherosclerosis.
Atherosclerosis
Identification of atherosclerosis-associated conformational heat shock protein 60 epitopes by phage display and structural alignment.
Atherosclerosis
Identification of immunoreactive epitopes of the Porphyromonas gingivalis heat shock protein in periodontitis and atherosclerosis.
Atherosclerosis
Identification of mono- or poly-specific monoclonal antibody to Porphyromonas gingivalis heat-shock protein 60.
Atherosclerosis
Immune regulation by oral tolerance induces alternate activation of macrophages and reduces markers of plaque destabilization in Apob(tm2Sgy)/Ldlr(tm1Her/J) mice.
Atherosclerosis
Immune responses to heat shock protein in Porphyromonas gingivalis-infected periodontitis and atherosclerosis patients.
Atherosclerosis
Immunization of low-density lipoprotein receptor deficient (LDL-RD) mice with heat shock protein 65 (HSP-65) promotes early atherosclerosis.
Atherosclerosis
Immunization with a combination of ApoB and HSP60 epitopes significantly reduces early atherosclerotic lesion in Apobtm2SgyLdlrtm1Her/J mice.
Atherosclerosis
Immunologic response enhances atherosclerosis-type 1 helper T cell (Th1)-to-type 2 helper T cell (Th2) shift and calcified atherosclerosis in Bacillus Calmette-Guerin (BCG)-treated apolipoprotein E-knockout (apo E-/-) mice.
Atherosclerosis
Immunology of atherosclerosis. Demonstration of heat shock protein 60 expression and T lymphocytes bearing alpha/beta or gamma/delta receptor in human atherosclerotic lesions.
Atherosclerosis
Immunopathogenic consequences of Chlamydia trachomatis 60 kDa heat shock protein expression in the female reproductive tract.
Atherosclerosis
Impact of seropositivity to Chlamydia pneumoniae and anti-hHSP60 on cardiovascular events in hemodialysis patients.
Atherosclerosis
Impairment of vascular function following BCG immunisation is associated with immune responses to HSP-60 in the cholesterol-fed rabbit.
Atherosclerosis
Implications of antibodies to heat-shock proteins in ischemic heart disease.
Atherosclerosis
Increased expression of HDJ-2 (hsp40) in carotid artery atherosclerosis: a novel heat shock protein associated with luminal stenosis and plaque ulceration.
Atherosclerosis
Increased serum levels of heat shock protein 70 are associated with low risk of coronary artery disease.
Atherosclerosis
Induction of Dendritic Cell-Mediated Activation of T Cells From Atherosclerotic Plaques by Human Heat Shock Protein 60.
Atherosclerosis
Induction of dendritic cell-mediated T-cell activation by modified but not native low-density lipoprotein in humans and inhibition by annexin a5: involvement of heat shock proteins.
Atherosclerosis
Induction of heat shock protein in monocytic cells by oxidized low density lipoprotein.
Atherosclerosis
Induction of oral tolerance as treatment or prevention of chronic diseases associated with Chlamydia pneumoniae infection--hypothesis.
Atherosclerosis
Induction of oral tolerance to HSP60 or an HSP60-peptide activates T cell regulation and reduces atherosclerosis.
Atherosclerosis
Infections, heat shock proteins, and atherosclerosis.
Atherosclerosis
Inflammation, heat shock proteins and periodontal pathogens in atherosclerosis: an immunohistologic study.
Atherosclerosis
Interaction of antibodies against cytomegalovirus with heat-shock protein 60 in pathogenesis of atherosclerosis.
Atherosclerosis
Interplay between HSP90 and Nrf2 pathways in diabetes-associated atherosclerosis.
Atherosclerosis
Intranasal immunization with heat shock protein 60 induces CD4(+) CD25(+) GARP(+) and type 1 regulatory T cells and inhibits early atherosclerosis.
Atherosclerosis
Low-Density Lipoproteins Induce Heat Shock Protein 27 Dephosphorylation, Oligomerization, and Subcellular Relocalization in Human Vascular Smooth Muscle Cells.
Atherosclerosis
MicroRNA-23a suppresses the apoptosis of inflammatory macrophages and foam cells in atherogenesis by targeting HSP90.
Atherosclerosis
Modulation of endothelial cell damages by anti-Hsp60 autoantibodies in systemic autoimmune diseases.
Atherosclerosis
Modulation of estrogen signaling by the novel interaction of heat shock protein 27, a biomarker for atherosclerosis, and estrogen receptor beta: mechanistic insight into the vascular effects of estrogens.
Atherosclerosis
Mucosal Tolerance to a Combination of ApoB and HSP60 Peptides Controls Plaque Progression and Stabilizes Vulnerable Plaque in Apob(tm2Sgy)Ldlr(tm1Her)/J Mice.
Atherosclerosis
Mycobacterial heat shock protein 65 (mbHSP65)-induced atherosclerosis: Preventive oral tolerization and definition of atheroprotective and atherogenic mbHSP65 peptides.
Atherosclerosis
Myocardial injury leads to a release of heat shock protein (hsp) 60 and a suppression of the anti-hsp65 immune response.
Atherosclerosis
Nasal immunization with heat shock protein 65 attenuates atherosclerosis and reduces serum lipids in cholesterol-fed wild-type rabbits probably through different mechanisms.
Atherosclerosis
Natural Monoclonal Antibody to Oxidized Low-Density Lipoprotein and Aggregatibacter actinomycetemcomitans.
Atherosclerosis
Non-Toxic Cadmium Concentrations Induce Vascular Inflammation and Promote Atherosclerosis.
Atherosclerosis
Oral administration of Lactococcus lactis delivered heat shock protein 65 attenuates atherosclerosis in low-density lipoprotein receptor-deficient mice.
Atherosclerosis
Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions.
Atherosclerosis
Oral Tolerization with Mycobacterial Heat Shock Protein 65 Reduces Chronic Experimental Atherosclerosis in Aged Mice.
Atherosclerosis
Peptide 19 of Porphyromonas gingivalis Heat Shock Protein Is a Potent Inducer of Low-Density Lipoprotein Oxidation.
Atherosclerosis
Pharmacological attenuation of apoptosis in reoxygenated endothelial cells.
Atherosclerosis
Porphyromonas gingivalis HSP60 peptides have distinct roles in the development of atherosclerosis.
Atherosclerosis
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Atherosclerosis
Prognostic value of antibody titre to heat-shock protein 65 on cardiovascular events.
Atherosclerosis
Promotion of atherosclerosis in high cholesterol diet-fed rabbits by immunization with the P277 peptide.
Atherosclerosis
Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78.
Atherosclerosis
Relationship between periodontal infections and systemic disease.
Atherosclerosis
Relationship between plasma cholesterol, von Willebrand factor concentrations, extent of atherosclerosis and antibody titres to heat shock proteins-60, -65 and -70 in cholesterol-fed rabbits.
Atherosclerosis
Role of heat shock protein 22 in the protective effect of geranylgeranylacetone in response to oxidized-LDL.
Atherosclerosis
Role of Heat Shock Protein 27 in Modulating Atherosclerotic Inflammation.
Atherosclerosis
Role of heat shock protein 65/60 in the pathogenesis of atherosclerosis.
Atherosclerosis
Serum Heat Shock Protein 27 Levels Represent a Potential Therapeutic Target for Atherosclerosis: Observations From a Human Cohort and Treatment of Female Mice.
Atherosclerosis
Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension.
Atherosclerosis
Social Determinants and Heat Shock Protein-70 Among African American and Non-Hispanic White Women With Atherosclerosis: A Pilot Study.
Atherosclerosis
Soy isoflavones reduce heat shock proteins in experimental atherosclerosis.
Atherosclerosis
Staining of endothelial cells and macrophages in atherosclerotic lesions with human heat-shock protein-reactive antisera.
Atherosclerosis
Stressing the obvious? Cell stress and cell stress proteins in cardiovascular disease.
Atherosclerosis
Subcutaneous immunization with heat shock protein-65 reduces atherosclerosis in Apoe(-/-) mice.
Atherosclerosis
Sublingual Vaccine with GroEL Attenuates Atherosclerosis.
Atherosclerosis
T-cell clonality to Porphyromonas gingivalis and human heat shock protein 60s in patients with atherosclerosis and periodontitis.
Atherosclerosis
T-cell reactivity against HSP60 relates to early but not advanced atherosclerosis.
Atherosclerosis
Targeting HSP90 Ameliorates Nephropathy and Atherosclerosis Through Suppression of NF-?B and STAT Signaling Pathways in Diabetic Mice.
Atherosclerosis
Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice.
Atherosclerosis
The GroEL protein of Porphyromonas gingivalis regulates atherogenic phenomena in endothelial cells mediated by upregulating toll-like receptor 4 expression.
Atherosclerosis
The Heat Shock Protein 27 Immune Complex Enhances Exosomal Cholesterol Efflux.
Atherosclerosis
The interaction and cellular localization of HSP27 and ERbeta are modulated by 17beta-estradiol and HSP27 phosphorylation.
Atherosclerosis
The relationship between HSP60 gene polymorphisms and susceptibility to atherosclerosis.
Atherosclerosis
The role of (auto-) immunity in atherogenesis.
Atherosclerosis
The role of heat shock protein (HSP) in atherosclerosis: Pathophysiology and clinical opportunities.
Atherosclerosis
The role of heat shock protein 90 in migration and proliferation of vascular smooth muscle cells in the development of atherosclerosis.
Atherosclerosis
The role of heat shock proteins in atherosclerosis.
Atherosclerosis
Tolerization against atherosclerosis using heat shock protein 60.
Atherosclerosis
Trimethylamine-N-oxide, as a risk factor for atherosclerosis, induces stress in J774A.1 murine macrophages.
Atherosclerosis
[Chronic bacterial infection as a risk factor for atherogenesis. The role of heat shock protein]
Atherosclerosis
[Recent progress in the development of atherosclerosis: role of heat shock protein].
Atrial Fibrillation
Association of high intracellular, but not serum, heat shock protein 70 with postoperative atrial fibrillation.
Atrial Fibrillation
Association of Met439Thr Substitution in Heat Shock Protein 70 Gene with Postoperative Atrial Fibrillation and Serum HSP70 Protein Levels.
Atrial Fibrillation
Atrial heat shock protein levels are associated with early postoperative and persistence of atrial fibrillation.
Atrial Fibrillation
Decreased Cardiac Expression of Heat Shock Protein 27 is Associated with Atrial Fibrillation in Patients with Rheumatic Heart Disease.
Atrial Fibrillation
Effects of a heat shock protein inducer on the atrial fibrillation substrate caused by acute atrial ischaemia.
Atrial Fibrillation
Electrophysiological Correlation and Prognostic Impact of Heat Shock Protein 27 in Atrial Fibrillation.
Atrial Fibrillation
Evaluating Serum Heat Shock Protein Levels as Novel Biomarkers for Atrial Fibrillation.
Atrial Fibrillation
Expression of mortalin in patients with chronic atrial fibrillation.
Atrial Fibrillation
Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.
Atrial Fibrillation
HALT & REVERSE: Hsf1 activators lower cardiomyocyt damage; towards a novel approach to REVERSE atrial fibrillation.
Atrial Fibrillation
Heat Shock Protein 70 Is Associated With Cardioversion Outcome and Recurrence of Symptomatic Recent Onset Atrial Fibrillation in Hypertensive Patients.
Atrial Fibrillation
Heat shock protein as a mediator between the effects of corticosteroids on atrial fibrillation recurrence after catheter ablation.
Atrial Fibrillation
Heat shock protein inducer GGA*-59 reverses contractile and structural remodeling via restoration of the microtubule network in experimental Atrial Fibrillation.
Atrial Fibrillation
Heat shock protein inducer modifies arrhythmogenic substrate and inhibits atrial fibrillation in the failing heart.
Atrial Fibrillation
Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation.
Atrial Fibrillation
HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes.
Atrial Fibrillation
Intracellular heat shock protein 70: a possible therapeutic target for preventing postoperative atrial fibrillation.
Atrial Fibrillation
Low preoperative HSP70 atrial myocardial levels correlate significantly with high incidence of postoperative atrial fibrillation after cardiac surgery.
Atrial Fibrillation
Overexpression of heat shock protein 60/10 in myocardium of patients with chronic atrial fibrillation.
Atrial Fibrillation
Response of circulating heat shock protein 70 and anti-heat shock protein 70 antibodies to catheter ablation of atrial fibrillation.
Atrial Fibrillation
Screening of novel HSP-inducing compounds to conserve cardiomyocyte function in experimental atrial fibrillation.
Atrial Fibrillation
The expression of heat shock protein 60 in myocardium of patients with chronic atrial fibrillation.
Atrial Fibrillation
The protective effect of heat shock protein 70 (Hsp70) in atrial fibrillation in various cardiomyopathy conditions.
Atrial Fibrillation
Unchanged heat-shock protein 70 expression in myocardium of patients with permanent atrial fibrillation.
Autoimmune Diseases
Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid.
Autoimmune Diseases
Activation of benign autoimmunity as both tumor and autoimmune disease immunotherapy: A comprehensive review.
Autoimmune Diseases
Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis.
Autoimmune Diseases
Aminoacyl-tRNA Synthetase-Interacting Multifunctional Protein 1/p43 Controls Endoplasmic Reticulum Retention of Heat Shock Protein gp96. Its Pathological Implications in Lupus-Like Autoimmune Diseases.
Autoimmune Diseases
Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases.
Autoimmune Diseases
Anti-HSP auto-antibodies enhance HSP-induced pro-inflammatory cytokine production in human monocytic cells via Toll-like receptors.
Autoimmune Diseases
Antibodies to human HSP60 in patients with juvenile chronic arthritis, diabetes mellitus, and cystic fibrosis.
Autoimmune Diseases
Antibody reactivity to mycobacterial 65 kDa heat shock protein: relevance to autoimmunity.
Autoimmune Diseases
Autoantibodies against chaperonin CCT in human sera with rheumatic autoimmune diseases: comparison with antibodies against other Hsp60 family proteins.
Autoimmune Diseases
Autolytic Mycobacterium leprae Hsp65 fragments may act as biological markers for autoimmune diseases.
Autoimmune Diseases
Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases.
Autoimmune Diseases
Chaperonin-Co-chaperonin Interactions.
Autoimmune Diseases
Chaperonopathies and Chaperonotherapy. Hsp60 as Therapeutic Target in Cancer: Potential Benefits and Risks.
Autoimmune Diseases
Characterization and expression of SpHsp60 in hemocytes after challenge to bacterial, osmotic and thermal stress from the mud crab Scylla paramamosain.
Autoimmune Diseases
Cloning and nucleotide sequence comparison of the groE operon of Pseudomonas aeruginosa and Burkholderia cepacia.
Autoimmune Diseases
Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells.
Autoimmune Diseases
Cross-reactive mycobacterial and self hsp60 epitope recognition in I-A(g7) expressing NOD, NOD-asp and Biozzi AB/H mice.
Autoimmune Diseases
Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells.
Autoimmune Diseases
Detection of autoantibodies to the 90 kDa heat shock protein in systemic lupus erythematosus and other autoimmune diseases.
Autoimmune Diseases
Development of IgG responses to mycobacterial antigens.
Autoimmune Diseases
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes.
Autoimmune Diseases
EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity.
Autoimmune Diseases
Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis.
Autoimmune Diseases
Elevation of IL-6 in transgenic mice results in increased levels of the 90 kDa heat shock protein (hsp90) and the production of anti-hsp90 antibodies.
Autoimmune Diseases
Elongated Flexuous Plant Virus-Derived Nanoparticles Functionalized for Autoantibody Detection.
Autoimmune Diseases
Expression of the human heat shock protein 60 in thyroid, pancreatic, hepatic and adrenal autoimmunity.
Autoimmune Diseases
Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region.
Autoimmune Diseases
Heat shock protein 60 mRNA is not increased in Graves' disease thyroid tissue.
Autoimmune Diseases
Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.
Autoimmune Diseases
Heat shock protein 90 inhibition: A potential double- or triple-edged sword in the treatment of mucous membrane pemphigoid.
Autoimmune Diseases
Heat shock protein 90 is critical for regulation of phenotype and functional activity of human T lymphocytes and NK cells.
Autoimmune Diseases
Heat shock protein and gliadin peptide promote development of peptidase antibodies in children with autism and patients with autoimmune disease.
Autoimmune Diseases
Heat shock protein bystander antigens for peptide immunotherapy in autoimmune disease.
Autoimmune Diseases
Heat shock protein reactivity of lymphocytes isolated from heterotopic rat cardiac allografts.
Autoimmune Diseases
Heat shock proteins and allograft rejection.
Autoimmune Diseases
Heat shock proteins in health and disease: therapeutic targets or therapeutic agents?
Autoimmune Diseases
Helicobacter pylori infection in connective tissue disorders is associated with high levels of antibodies to mycobacterial hsp65 but not to human hsp60.
Autoimmune Diseases
Highly autoproliferative T cells specific for 60-kDa heat shock protein produce IL-4/IL-10 and IFN-gamma and are protective in adjuvant arthritis.
Autoimmune Diseases
HSP60 as a drug target.
Autoimmune Diseases
HSP60: issues and insights on its therapeutic use as an immunoregulatory agent.
Autoimmune Diseases
HSP70-1 promoter region polymorphism tested in three autoimmune diseases.
Autoimmune Diseases
HSP70i accelerates depigmentation in a mouse model of autoimmune vitiligo.
Autoimmune Diseases
Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy.
Autoimmune Diseases
Hsp90 blockade modulates bullous pemphigoid IgG-induced IL-8 production by keratinocytes.
Autoimmune Diseases
Human Hsp60: bacterial expression, purification, development of monoclonal antibodies and a sandwich ELISA for quantitation.
Autoimmune Diseases
Identification of a 40-kDa human protein that cross-reacts with prokaryotic hsp60/chaperonins.
Autoimmune Diseases
Identification of human heat shock protein 60 (Hsp60) and anti-Hsp60 antibodies in the peripheral circulation of normal individuals.
Autoimmune Diseases
Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progression.
Autoimmune Diseases
Immune recognition of human Hsp60 by Lyme disease patient sera.
Autoimmune Diseases
Immune responses to heat shock protein in Porphyromonas gingivalis-infected periodontitis and atherosclerosis patients.
Autoimmune Diseases
Immune responses to Mycobacterial heat shock protein 70 accompany self-reactivity to human BiP in rheumatoid arthritis.
Autoimmune Diseases
Immune tolerance therapies for autoimmune diseases based on heat shock protein T-cell epitopes.
Autoimmune Diseases
Immunomodulation and protection induced by DNA-hsp65 vaccination in an animal model of arthritis.
Autoimmune Diseases
Immunomodulatory effects of heat shock protein 90 inhibition on humoral immune responses.
Autoimmune Diseases
Induction of endothelial cell apoptosis by the binding of anti-endothelial cell antibodies to Hsp60 in vasculitis-associated systemic autoimmune diseases.
Autoimmune Diseases
Infection, autoimmunity and autoimmune disease.
Autoimmune Diseases
Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60.
Autoimmune Diseases
Inhibitory effects of heat shock protein 90 blockade on proinflammatory human Th1 and Th17 cell subpopulations.
Autoimmune Diseases
Interferon gamma and iodide increase the inducibility of the 72 kD heat shock protein in cultured human thyroid epithelial cells.
Autoimmune Diseases
Lactoferrin triggers in vitro proliferation of T cells of Lewis rats submitted to mycobacteria-induced adjuvant arthritis.
Autoimmune Diseases
Low levels of heat shock proteins-60 and -65 autoantibodies in Sjögren's syndrome.
Autoimmune Diseases
Modulation of pristane-induced arthritis by mycobacterial antigens.
Autoimmune Diseases
Molecular cloning, characterization and expression patterns of HSP60 in the grass carp (Ctenopharyngodon idella).
Autoimmune Diseases
Mucosal expression by B7-positive cells of the 60-kilodalton heat-shock protein in inflammatory bowel disease.
Autoimmune Diseases
Mycobacterial and mouse HSP70 have immuno-modulatory effects on dendritic cells.
Autoimmune Diseases
Oral administration of HSP-containing E. coli extract OM-89 has suppressive effects in autoimmunity. Regulation of autoimmune processes by modulating peripheral immunity towards hsp's?
Autoimmune Diseases
Pep19 drives epitope spreading in periodontitis and periodontitis-associated autoimmune diseases.
Autoimmune Diseases
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Autoimmune Diseases
Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by antisense oligonucleotide treatment.
Autoimmune Diseases
Proposing BCG Vaccination for Mycobacterium avium ss. paratuberculosis (MAP) Associated Autoimmune Diseases.
Autoimmune Diseases
Recognition of heat shock protein 60 epitopes in children with type 1 diabetes.
Autoimmune Diseases
Robust immunoreactivity of teenager sera against peptide 19 from Porphyromonas gingivalis HSP60.
Autoimmune Diseases
Role of hsp90 in systemic lupus erythematosus and its clinical relevance.
Autoimmune Diseases
Sequence homologies between hsp60 and autoantigens.
Autoimmune Diseases
Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT.
Autoimmune Diseases
Serum heat shock protein 60 can predict remission of flare-up in juvenile idiopathic arthritis.
Autoimmune Diseases
Specific regulation of HSPs in human tumor cell lines by PSK.
Autoimmune Diseases
Susceptibility to pristane-induced arthritis is altered with changes in bowel flora.
Autoimmune Diseases
Takayasu's arteritis: role of Mycobacterium tuberculosis and its 65 kDa heat shock protein.
Autoimmune Diseases
Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling.
Autoimmune Diseases
The 8.5-kb PstI allele of the stress protein gene, Hsp70-2: an independent risk factor for systemic lupus erythematosus in African Americans?
Autoimmune Diseases
The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.
Autoimmune Diseases
The immune response to mycobacterial heat shock proteins.
Autoimmune Diseases
Topically Applied Hsp90 Blocker 17AAG Inhibits Autoantibody-Mediated Blister-Inducing Cutaneous Inflammation.
Autoimmune Diseases
What is the evidence that mycobacteria are associated with the pathogenesis of Sjogren's syndrome?
Autoimmune Diseases
[Autoimmune diseases and stress proteins]
Autoimmune Diseases
[Clinical immunology of tuberculosis]
Autoimmune Diseases
[Detection of humoral immune response to inner ear proteins in patients with sensorineural hearing loss]
Autoimmune Diseases
[Induction of mucosal immunity to mycobacterial heat shock protein (hsp) 65 by colonic inoculation of plasmid DNA encoding hsp65]
Axial Spondyloarthritis
IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis.
Axial Spondyloarthritis
Plasma heat shock protein 90 levels in patients with spondyloarthritis and their relation to structural changes: a cross-sectional study.
Babesiosis
Expression analysis of heat shock protein 20 and rhoptry-associated protein 1a in sexual stages and kinetes of Babesia bigemina.
Bacteremia
Comparative Exoproteomics and Host Inflammatory Response in Staphylococcus aureus Skin and Soft Tissue Infections, Bacteremia, and Subclinical Colonization.
Bacterial Infections
Anti-60-kDa heat shock protein antibodies in fetal serum: a biomarker for unexplained small for gestational age fetuses.
Bacterial Infections
Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk.
Bacterial Infections
Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.
Bacterial Infections
Cloning and identification of grass carp transcription factor HSF1 and its characterization involving the production of fish HSP70.
Bacterial Infections
Cloning, molecular characterization and expression analysis of heat shock cognate 70 (Hsc70) cDNA from turbot (Scophthalmus maximus).
Bacterial Infections
Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis.
Bacterial Infections
Expression analysis of heat shock protein genes during Aeromonas hydrophila infection in rohu, Labeo rohita, with special reference to molecular characterization of Grp78.
Bacterial Infections
Genome-wide identification of hsp40 genes in channel catfish and their regulated expression after bacterial infection.
Bacterial Infections
Heat shock protein 70 from Litopenaeus vannamei (LvHSP70) is involved in the innate immune response against white spot syndrome virus (WSSV) infection.
Bacterial Infections
Heat shock protein 90: its inhibition and function.
Bacterial Infections
Heat shock protein profiles on the protein and gene expression levels in olive flounder kidney infected with Streptococcus parauberis.
Bacterial Infections
Heat shock proteins form part of a danger signal cascade in response to lipopolysaccharide and GroEL.
Bacterial Infections
Heat shock proteins protect platyfish (Xiphophorus maculatus) from Yersinia ruckeri induced mortality.
Bacterial Infections
Hsp90, Hsp60 and sHsp families of heat shock protein genes in channel catfish and their expression after bacterial infections.
Bacterial Infections
Identification of atherosclerosis-associated conformational heat shock protein 60 epitopes by phage display and structural alignment.
Bacterial Infections
Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis.
Bacterial Infections
Multiplex immune-related genes expression analysis response to bacterial challenge in mud crab, Scylla paramamosain.
Bacterial Infections
Significance of serum antibodies against HSP 60 and HSP 70 for the diagnostic of infectious diseases.
Bacterial Infections
Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide.
Bacterial Infections
Understanding GroEL and DnaK Stress Response Proteins as Antigens for Bacterial Diseases.
Bacterial Infections
[Chronic bacterial infection as a risk factor for atherogenesis. The role of heat shock protein]
Bacterial Infections
[Modification of the immune system by heat shock protein induced by bacterial infection]
Bacterial Infections
[Participation of heat shock proteins in modulation of NF-?B transcription factor activation during bacterial infections].
Barrett Esophagus
Discovery of a Novel Connecting Link between Renin-Angiotensin System and Cancer in Barrett's Esophagus by Proteomic Screening.
Bartonella Infections
Detection of Bartonella henselae DNA in clinical samples including peripheral blood of immune competent and immune compromised patients by three nested amplifications.
Bartonella Infections
Detection of Bartonella species from ticks, mites and small mammals in Korea.
Behcet Syndrome
Aberrant Activation of Heat Shock Protein 60/65 Reactive T Cells in Patients with Behcet's Disease.
Behcet Syndrome
Bioinformatics-Driven New Immune Target Discovery in Disease.
Behcet Syndrome
Characterization of T cells specific for an epitope of human 60-kD heat shock protein (hsp) in patients with Behcet's disease (BD) in Japan.
Behcet Syndrome
Involvement of Th1 cells and heat shock protein 60 in the pathogenesis of intestinal Behcet's disease.
Behcet Syndrome
Oral tolerization with peptide 336-351 linked to cholera toxin B subunit in preventing relapses of uveitis in Behcet's disease.
Behcet Syndrome
The role of heat shock protein 60, vascular endothelial growth factor and antiphospholipid antibodies in Behçet disease.
beta-Thalassemia
Effect of zinc supplementation on serum antibody titers to heat shock protein 27 in patients with thalassemia major.
beta-Thalassemia
Increased Serum Heat Shock Protein 27 Antibody Titers and Prooxidant-Antioxidant Balance in Patients with Beta-Thalassemia Major.
Biliary Atresia
Analysis of Biliary Epithelial-Mesenchymal Transition in Portal Tract Fibrogenesis in Biliary Atresia.
Biliary Atresia
Elevated serum heat shock protein 70 and liver stiffness reflect hepatic dysfunction and severity in postoperative biliary atresia.
Biliary Atresia
Identification of HSP90 as potential biomarker of biliary atresia using two-dimensional electrophoresis and mass spectrometry.
Blast Crisis
Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.
Blindness
Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma.
Blister
Heat shock protein 47 is up-regulated in conjunctival bleb scarring after filtration surgery in rats.
Blister
Heat shock protein 90 inhibition: A potential double- or triple-edged sword in the treatment of mucous membrane pemphigoid.
Blister
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Blister
Heat-shock protein 60 translocates to the surface of apoptotic cells and differentiated megakaryocytes and stimulates phagocytosis.
Blister
Molecular chaperones are targets of autoimmunity in Ro(SS-A) immune mice.
Blister
Serial Changes of Heat Shock Protein 70 and Interleukin-8 in Burn Blister Fluid.
Bluetongue
Hsp90 chaperones Bluetongue virus proteins and prevents proteasomal degradation.
Bone Diseases, Metabolic
Heat shock protein 60 protects skeletal tissue against glucocorticoid-induced bone mass loss by regulating osteoblast survival.
Bone Diseases, Metabolic
Inhibitors of heat shock protein 90 augment endothelin?1?induced heat shock protein 27 through the SAPK/JNK signaling pathway in osteoblasts.
Bone Resorption
Characterization of a natural mouse monoclonal antibody recognizing epitopes shared by oxidized low-density lipoprotein and chaperonin 60 of Aggregatibacter actinomycetemcomitans.
Bone Resorption
Heat shock protein 60 causes osteoclastic bone resorption via toll-like receptor-2 in estrogen deficiency.
Bone Resorption
Homogeneous Escherichia coli chaperonin 60 induces IL-1 beta and IL-6 gene expression in human monocytes by a mechanism independent of protein conformation.
Bone Resorption
Increased circulating heat shock protein 60 induced by menopause, stimulates apoptosis of osteoblast-lineage cells via up-regulation of toll-like receptors.
Bone Resorption
Molecular chaperones stimulate bone resorption.
Bone Resorption
Natural Monoclonal Antibody to Oxidized Low-Density Lipoprotein and Aggregatibacter actinomycetemcomitans.
Bone Resorption
Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
Bone Resorption
Spondyloarthropathies and bone resorption: a possible role of heat shock protein (Hsp70).
Bone Resorption
Tannerella forsythia GroEL induces inflammatory bone resorption and synergizes with interleukin-17.
Bone Resorption
The potent bone-resorbing mediator of Actinobacillus actinomycetemcomitans is homologous to the molecular chaperone GroEL.
Bone Resorption
The virulence factor GroEL promotes gelatinase secretion from cells in the osteoblast lineage: Implication for direct crosstalk between bacteria and adult cells.
Borna Disease
Heat shock cognate protein 70 controls Borna disease virus replication via interaction with the viral non-structural protein X.
Borna Disease
Molecular chaperone BiP interacts with Borna disease virus glycoprotein at cell surface.
Bradycardia
Potentiation of baroreceptor reflex response by heat shock protein 70 in nucleus tractus solitarii confers cardiovascular protection during heatstroke.
Brain Abscess
Nestin and small heat shock protein expression on reactive astrocytes and endothelial cells in cerebral abscess.
Brain Concussion
[Changes of HSP70, bFGF and TGF-beta1 expression in rat brain after concussion]
Brain Death
Brain death induces renal expression of heme oxygenase-1 and heat shock protein 70.
Brain Death
Direct peritoneal resuscitation reduces intestinal permeability after brain death.
Brain Death
Renal expression of heat shock proteins after brain death induction in rats.
Brain Diseases
A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques.
Brain Diseases
A molecular chaperone for mitochondrial complex I assembly is mutated in a progressive encephalopathy.
Brain Diseases
Biallelic Variants in CNPY3, Encoding an Endoplasmic Reticulum Chaperone, Cause Early-Onset Epileptic Encephalopathy.
Brain Diseases
Druggability of Mortalin for Cancer and Neuro-Degenerative Disorders.
Brain Diseases
Early diffusion weighted imaging and expression of heat shock protein 70 in newborn pigs with hypoxic ischaemic encephalopathy.
Brain Diseases
FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy.
Brain Diseases
Geldanamycin treatment during cerebral ischemia/reperfusion attenuates p44/42 mitogen-activated protein kinase activation and tissue damage.
Brain Diseases
Molecular chaperone treats encephalopathy.
Brain Diseases
Novel interactions of GRP78: UPR and estrogen responses in the brain.
Brain Diseases
Opportunities and Challenges for Molecular Chaperone Modulation to Treat Protein-Conformational Brain Diseases.
Brain Diseases
Pallido-nigral spheroids in nonhuman primates: accumulation of heat shock proteins in astroglial processes.
Brain Diseases
Stress protein inclusions in cerebral vessels in dialysis encephalopathy.
Brain Diseases
Stress response in the central nervous system of a transgenic mouse model of bovine spongiform encephalopathy.
Brain Edema
Aging enhances intracerebral hemorrhage-induced brain injury in rats.
Brain Edema
Attenuating brain edema, hippocampal oxidative stress, and cognitive dysfunction in rats using hyperbaric oxygen preconditioning during simulated high-altitude exposure.
Brain Edema
Neuroprotective effects of 5-HT3 receptor antagonist ondansetron on morphine withdrawal induced brain edema formation, blood-brain barrier dysfunction, neuronal injuries, glial activation and heat shock protein upregulation in the brain.
Brain Edema
RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in rats.
Brain Edema
Role of neurochemicals in brain edema and cell changes following hyperthermic brain injury in the rat.
Brain Edema
[Effect of heat shock protein 70 on nuclear factor-KappaB/inhibitor protein-alpha of nuclear factor-KappaB in brain edema induced by infection in rat]
Brain Edema
[Effects of Cinnabar and Realgar in Angong Niuhuang powder on heat shock protein, nitric oxide synthase and inflammatory cytokines in contusion cerebral edema]
Brain Edema
[Heat shock protein 70 induction by heat stress suppress interleukin-1beta and tumor necrosis factor-alpha levels in the brain tissue in rats with infectious brain edema]
Brain Infarction
Intranasal basic fibroblast growth factor attenuates endoplasmic reticulum stress and brain injury in neonatal hypoxic-ischaemic injury.
Brain Injuries
Antioxidant compounds EGB-761 and BN-520 21 attenuate heat shock protein (HSP 72 kD) response, edema and cell changes following hyperthermic brain injury. An experimental study using immunohistochemistry in the rat.
Brain Injuries
Calorie restriction and stroke.
Brain Injuries
Conditioning effects of repetitive mild neurotrauma on motor function in an animal model of focal brain injury.
Brain Injuries
Decreased S100B serum levels after treatment in bipolar patients in a manic phase.
Brain Injuries
Dual inhibitory roles of geldanamycin on the c-Jun NH(2)-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury.
Brain Injuries
Effects of 2-Deoxyglucose on ischemic brain injuries in rats.
Brain Injuries
Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood-brain barrier disruption after ischemic brain injury.
Brain Injuries
Exercise Preconditioning Attenuates Neurological Injury by Preserving Old and Newly Formed HSP72-Containing Neurons in Focal Brain Ischemia Rats.
Brain Injuries
Expression of brain-derived neurotrophic factor, nerve growth factor, and heat shock protein HSP70 following fluid percussion brain injury in rats.
Brain Injuries
Expression of heat shock protein after +Gz exposure and its protective effects on +Gz-induced brain injury.
Brain Injuries
Geldanamycin inhibits Fas signaling pathway and protects neurons against ischemia.
Brain Injuries
Geldanamycin reduced brain injury in mouse model of intracerebral hemorrhage.
Brain Injuries
Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1? signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats.
Brain Injuries
Heat Shock Protein 70 (HSP70) Induction: Chaperonotherapy for Neuroprotection after Brain Injury.
Brain Injuries
Heat shock protein 70 expression in epilepsy suggests stress rather than protection.
Brain Injuries
Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage.
Brain Injuries
Heat shock protein modulation of KATP and KCa channel cerebrovasodilation after brain injury.
Brain Injuries
Heat-shock protein 72 expression in excitotoxic versus penetrating injuries of the rodent cerebral cortex.
Brain Injuries
Hypothermia decreases excitatory neurotransmitter release in bacterial meningitis in rabbits.
Brain Injuries
Immunolocalization of heat shock protein after fluid percussive brain injury and relationship to breakdown of the blood-brain barrier.
Brain Injuries
Intranasal basic fibroblast growth factor attenuates endoplasmic reticulum stress and brain injury in neonatal hypoxic-ischaemic injury.
Brain Injuries
Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4- and MyD88-dependent pathway.
Brain Injuries
Neurofilament heavy chain and heat shock protein 70 as markers of seizure-related brain injury.
Brain Injuries
Neuroprotective Effects of Valproic Acid on Blood-Brain Barrier Disruption and Apoptosis-Related Early Brain Injury in Rats Subjected to Subarachnoid Hemorrhage Are Modulated by Heat Shock Protein 70/Matrix Metalloproteinases and Heat Shock Protein 70/AKT Pathways.
Brain Injuries
Peripherally misfolded proteins exacerbate ischemic stroke-induced neuroinflammation and brain injury.
Brain Injuries
Pharmacological induction of the 70-kDa heat shock protein protects against brain injury.
Brain Injuries
RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in rats.
Brain Injuries
Reactive astrocytes in acute stage after experimental brain injury: relationship to extravasated plasma protein and expression of heat shock protein.
Brain Injuries
Regulation of inflammatory transcription factors by heat shock protein 70 in primary cultured astrocytes exposed to oxygen-glucose deprivation.
Brain Injuries
The 70-kDa heat shock protein (Hsp70) as a therapeutic target for stroke.
Brain Injuries
[Protective effect of prostaglandin E1 against brain injury induced by hyperoxia in neonatal rats].
Brain Injuries, Traumatic
72-kDa heat shock protein and mRNA expression after controlled cortical impact injury with hypoxemia in rats.
Brain Injuries, Traumatic
?-adrenergic receptor inhibition affects cerebral glucose metabolism, motor performance, and inflammatory response after traumatic brain injury.
Brain Injuries, Traumatic
Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy.
Brain Injuries, Traumatic
Anesthesia for euthanasia influences mRNA expression in healthy mice and after traumatic brain injury.
Brain Injuries, Traumatic
Expression of heat shock protein 70 and Annexin A1 in serum of patients with acutely severe traumatic brain injury.
Brain Injuries, Traumatic
Hyperglycemia and antibody titres against heat shock protein 27 in traumatic brain injury patients on parenteral nutrition.
Brain Injuries, Traumatic
Immunolocalization of Toll-like receptors 2 and 4 as well as their endogenous ligand, heat shock protein 70, in rat traumatic brain injury.
Brain Injuries, Traumatic
Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children.
Brain Injuries, Traumatic
Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression.
Brain Injuries, Traumatic
Optical imaging of cell death in traumatic brain injury using a heat shock protein-90 alkylator.
Brain Injuries, Traumatic
Patterns of heat-shock protein 70 biosynthesis following human traumatic brain injury.
Brain Injuries, Traumatic
Regional induction of c-fos and heat shock protein-72 mRNA following fluid-percussion brain injury in the rat.
Brain Injuries, Traumatic
Subcellular stress response after traumatic brain injury.
Brain Injuries, Traumatic
Temporal and regional profiles of cytoskeletal protein accumulation in the rat brain following traumatic brain injury.
Brain Injuries, Traumatic
The 70 kDa heat shock protein protects against experimental traumatic brain injury.
Brain Ischemia
10 kD mitochondrial matrix heat shock protein mRNA is induced following global brain ischemia in the rat.
Brain Ischemia
70-kDa Heat Shock Protein Downregulates Dynamin in Experimental Stroke: A New Therapeutic Target?
Brain Ischemia
A prospective evaluation of the heat shock protein 70 gene polymorphisms and the risk of stroke.
Brain Ischemia
Acceleration of TDP43 and FUS/TLS protein expressions in the preconditioned hippocampus following repeated transient ischemia.
Brain Ischemia
Alpha2 adrenoreceptor agonist regulates protein kinase C-induced heat shock protein 27 phosphorylation in C6 glioma cells.
Brain Ischemia
Angiotensin II AT1 receptor blockade abolishes brain microvascular inflammation and heat shock protein responses in hypertensive rats.
Brain Ischemia
Cellular and Subcellular Localization of Endoplasmic Reticulum Chaperone GRP78 Following Transient Focal Cerebral Ischemia in Rats.
Brain Ischemia
Combined prostaglandin E1 and lithium exert potent neuroprotection in a rat model of cerebral ischemia.
Brain Ischemia
Correlation between changes in apparent diffusion coefficient and induction of heat shock protein, cell-specific injury marker expression, and protein synthesis reduction on diffusion-weighted magnetic resonance images after temporary focal cerebral ischemia in rats.
Brain Ischemia
Different thresholds of HSP70 and HSC70 heat shock mRNA induction in post-ischemic gerbil brain.
Brain Ischemia
Differential cellular distribution and dynamics of HSP70, cyclooxygenase-2, and c-Fos in the rat brain after transient focal ischemia or kainic acid.
Brain Ischemia
Dual inhibitory roles of geldanamycin on the c-Jun NH(2)-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury.
Brain Ischemia
Early 72-kDa heat shock protein induction in microglial cells following focal ischemia in the rat brain.
Brain Ischemia
Effects of exogenous vitamin D on endoplasmic reticulum stress-related factors in the vitamin D deficiency rats with cerebral ischemia.
Brain Ischemia
Effects of global cerebral ischemia and preconditioning on heat shock protein 27 immunocontent and phosphorylation in rat hippocampus.
Brain Ischemia
Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse.
Brain Ischemia
Effects of hsp70.1 gene knockout on the mitochondrial apoptotic pathway after focal cerebral ischemia.
Brain Ischemia
Expression of glial fibrillary acidic protein in areas of focal cerebral ischemia accompanies neuronal expression of 72-kDa heat shock protein.
Brain Ischemia
Geldanamycin inhibits Fas signaling pathway and protects neurons against ischemia.
Brain Ischemia
Geranylgeranylacetone protects against cerebral ischemia and reperfusion injury: HSP90 and eNOS phosphorylation involved.
Brain Ischemia
Glutamate receptor antagonists modulate heat shock protein response in focal brain ischemia.
Brain Ischemia
Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.
Brain Ischemia
Heat shock protein 72 inhibits c-Jun N-terminal kinase 3 signaling pathway via Akt1 during cerebral ischemia.
Brain Ischemia
Heat shock protein 72 overexpression protects against hyperthermia, circulatory shock, and cerebral ischemia during heatstroke.
Brain Ischemia
Heat shock protein expression protects against cerebral ischemia and monoamine overload in rat heatstroke.
Brain Ischemia
Heat shock protein signaling in brain ischemia and injury.
Brain Ischemia
Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling.
Brain Ischemia
HSPA9/Mortalin mediates axo-protection and modulates mitochondrial dynamics in neurons.
Brain Ischemia
Human-derived physiological heat shock protein 27 complex protects brain after focal cerebral ischemia in mice.
Brain Ischemia
Immunohistochemical assessment of constitutive and inducible heat-shock protein 70 and ubiquitin in human cerebellum and caudate nucleus.
Brain Ischemia
Immunohistochemical visualization of heat shock protein-70 in the gerbil hippocampus following repeated brief cerebral ischemia.
Brain Ischemia
Indomethacin attenuates early increases in inducible heat shock protein 70 after cerebral ischemia/reperfusion in piglets
Brain Ischemia
Indomethacin attenuates early increases in inducible heat shock protein 70 after cerebral ischemia/reperfusion in piglets.
Brain Ischemia
Induction of 27-kDa heat shock protein following cerebral ischemia in a rat model of ischemic tolerance.
Brain Ischemia
Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat.
Brain Ischemia
Induction of c-fos and c-jun gene products and heat shock protein after brief and prolonged cerebral ischemia in gerbils.
Brain Ischemia
Induction of heat shock protein 40 and GrpE mRNAs following transient focal cerebral ischemia in the rat.
Brain Ischemia
Induction of heat shock protein 70 and glial fibrillary acidic protein in the postischemic gerbil hippocampus.
Brain Ischemia
Induction of mitochondrial heat shock protein 60 and 10 mRNAs following transient focal cerebral ischemia in the rat.
Brain Ischemia
Involvement of the dual-specificity phosphatase M3/6 in c-Jun N-terminal kinase inactivation following cerebral ischemia in the rat hippocampus.
Brain Ischemia
Ischemic preconditioning prevents protein aggregation after transient cerebral ischemia.
Brain Ischemia
Ischemic preconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PERK pathway.
Brain Ischemia
Lack of neuroprotection by heat shock protein 70 overexpression in a mouse model of global cerebral ischemia.
Brain Ischemia
miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo.
Brain Ischemia
Mitochondrial heat shock protein 60 is increased in cerebrospinal fluid following pediatric traumatic brain injury.
Brain Ischemia
Neuroprotection of hypoxic postconditioning against global cerebral ischemia through influencing posttranslational regulations of heat shock protein 27 in adult rats.
Brain Ischemia
Neuroprotective effect of a heat shock protein inducer, geranylgeranylacetone in permanent focal cerebral ischemia.
Brain Ischemia
Neurotherapeutic activity of the recombinant heat shock protein Hsp70 in a model of focal cerebral ischemia in rats.
Brain Ischemia
Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia.
Brain Ischemia
Overexpression of rat heat shock protein 70 reduces neuronal injury after transient focal ischemia, transient global ischemia, or kainic acid-induced seizures.
Brain Ischemia
Oxidative stress and ischemic injuries in heat stroke.
Brain Ischemia
Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion.
Brain Ischemia
Phosphorylation enhances recombinant HSP27 neuroprotection against focal cerebral ischemia in mice.
Brain Ischemia
Phosphorylation of HSP27 by Protein Kinase D Is Essential for Mediating Neuroprotection against Ischemic Neuronal Injury.
Brain Ischemia
Preconditioning with +Gz acceleration (head-to-foot inertial load) produces neuroprotection against transient focal cerebral ischemia in rats.
Brain Ischemia
Preferential expression of HSC70 heat shock mRNA in gerbil heart after transient brain ischemia.
Brain Ischemia
Prior ischemic stress protects against experimental stroke.
Brain Ischemia
Protective HSP70 Induction by Z-Ligustilide against Oxygen-Glucose Deprivation Injury via Activation of the MAPK Pathway but Not of HSF1.
Brain Ischemia
Regional expression of heat shock protein-70 mRNA and c-fos mRNA following focal ischemia in rat brain.
Brain Ischemia
Regulation of apoptotic and inflammatory cell signaling in cerebral ischemia: the complex roles of heat shock protein 70.
Brain Ischemia
Serum levels of heat shock protein 27 in patients with acute ischemic stroke.
Brain Ischemia
Stoichiometric Analysis of Shifting in Subcellular Compartmentalization of HSP70 within Ischemic Penumbra.
Brain Ischemia
Suppression subtraction hybridization and northern analysis reveal upregulation of heat shock, trkB, and sodium calcium exchanger genes following global cerebral ischemia in the rat.
Brain Ischemia
Synergistic induction of HSP40 and HSC70 in the mouse hippocampal neurons after cerebral ischemia and ischemic tolerance in gerbil hippocampus.
Brain Ischemia
Targeted hsp70.1 disruption increases infarction volume after focal cerebral ischemia in mice.
Brain Ischemia
Targeting expression of hsp70i to discrete neuronal populations using the Lmo-1 promoter: assessment of the neuroprotective effects of hsp70i in vivo and in vitro.
Brain Ischemia
TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells.
Brain Ischemia
Time course of brain neuronal degeneration and heat shock protein (72) expression following neck tourniquet-induced cerebral ischemia in the rat.
Brain Ischemia
Upregulation of dihydropyrimidinase-related protein 2, spectrin alpha II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats--a proteomics approach.
Brain Ischemia
Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction.
Brain Ischemia
Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppression Reversal.
Brain Ischemia
[Effect of dl-3-N-butylphthalide on the expression of hsp70 mRNA and c-fos in transient cerebral ischemic and reperfused rat brain]
Brain Ischemia
[Effects of Naomaitong Recipe on expressions of nuclear factor-kappaB and nitric-oxide synthases in brain tissue after focal cerebral ischemia reperfusion in aged rats.]
Brain Ischemia
[Mild hypothermia combined with hydrogen sulfide alleviates hippocampal endoplasmic reticulum stress after global cerebral ischemia-reperfusion].
Brain Ischemia
[Recent advances in pathophysiology and treatment of acute ischemic stroke]
Brain Neoplasms
Acquired resistance to 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) in glioblastoma cells.
Brain Neoplasms
Chaperonins in cancer: Expression, function, and migration in extracellular vesicles.
Brain Neoplasms
Concomitant alterations in distribution of 70 kDa heat shock proteins, cytoskeleton and organelles in heat shocked 9L cells.
Brain Neoplasms
Correlation between the progressive cytoplasmic expression of a novel small heat shock protein (Hsp16.2) and malignancy in brain tumors.
Brain Neoplasms
Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis.
Brain Neoplasms
Elevated levels of mortalin expression in human brain tumors.
Brain Neoplasms
Expression analysis of mortalin, a unique member of the Hsp70 family of proteins, in rat tissues.
Brain Neoplasms
Expression of heat shock proteins in brain tumors.
Brain Neoplasms
Geldanamycin induction of grp78 requires activation of reactive oxygen species via ER stress responsive elements in 9L rat brain tumour cells.
Brain Neoplasms
Gene expression profiling of metastatic brain cancer.
Brain Neoplasms
GRP78/BiP modulation of GRP78/BiP in altering sensitivity to chemotherapy.
Brain Neoplasms
Heat shock protein 70-binding protein 1 is highly expressed in high-grade gliomas, interacts with multiple heat shock protein 70 family members, and specifically binds brain tumor cell surfaces.
Brain Neoplasms
Immobilization stress induces the expression of alphaB-crystallin in rat hippocampus: implications of glial activation in stress-mediated hippocampal degeneration.
Brain Neoplasms
Immunoexpression patterns for Hypoxia-inducible Factor-1? and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
Brain Neoplasms
Involvement of Calcium-Mediated Reactive Oxygen Species in Inductive GRP78 Expression by Geldanamycin in 9L Rat Brain Tumor Cells.
Brain Neoplasms
Involvement of heat shock elements and basal transcription elements in the differential induction of the 70-kDa heat shock protein and its cognate by cadmium chloride in 9L rat brain tumor cells.
Brain Neoplasms
Mitochondrial calcium-mediated reactive oxygen species are essential for the rapid induction of the grp78 gene in 9L rat brain tumour cells.
Brain Neoplasms
Novel Functional Association of Serine Palmitoyltransferase Subunit 1-A Peptide in Sphingolipid Metabolism with Cytochrome P4501A1 Transactivation and Proliferative Capacity of the Human Glioma LN18 Brain Tumor Cell Line.
Brain Neoplasms
Pilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children.
Brain Neoplasms
Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.
Brain Neoplasms
Potential biomarkers of childhood brain tumor identified by proteomics of cerebrospinal fluid from extraventricular drainage (EVD).
Brain Neoplasms
Proteomic and Mitochondrial Genomic Analyses of Pediatric Brain Tumors.
Brain Neoplasms
Rapid induction of the Grp78 gene by cooperative actions of okadaic acid and heat-shock in 9L rat brain tumor cells--involvement of a cAMP responsive element-like promoter sequence and a protein kinase A signaling pathway.
Brain Neoplasms
Thapsigargin-induced grp78 expression is mediated by the increase of cytosolic free calcium in 9L rat brain tumor cells.
Brain Neoplasms
The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.
Brain Neoplasms
Transferrin Modified GSH Sensitive Hyaluronic Acid Derivative Micelle to Deliver HSP90 Inhibitors to Enhance the Therapeutic Efficacy of Brain Cancers.
Breast Neoplasms
"UPRegulation" of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses.
Breast Neoplasms
(89)Zr-trastuzumab PET visualises HER2 downregulation by the HSP90 inhibitor NVP-AUY922 in a human tumour xenograft.
Breast Neoplasms
17-Allyamino-17-demethoxygeldanamycin and 17-NN-dimethyl ethylene diamine-geldanamycin have cytotoxic activity against multiple gynecologic cancer cell types.
Breast Neoplasms
17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2.
Breast Neoplasms
17?AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA?MB?231 breast cancer cells.
Breast Neoplasms
17beta-hydroxysteroid dehydrogenase type 5 is negatively correlated to apoptosis inhibitor GRP78 and tumor-secreted protein PGK1, and modulates breast cancer cell viability and proliferation.
Breast Neoplasms
19-substituted Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors: Biological Activity and Decreased Off-target Toxicity.
Breast Neoplasms
89Zr-trastuzumab and 89Zr-bevacizumab PET to evaluate the effect of the HSP90 inhibitor NVP-AUY922 in metastatic breast cancer patients.
Breast Neoplasms
?B-crystallin Expression in Breast Cancer is Associated with Brain Metastasis.
Breast Neoplasms
A 27 kDa heat shock protein that has anomalous prognostic powers in early and advanced breast cancer.
Breast Neoplasms
A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2.
Breast Neoplasms
A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.
Breast Neoplasms
A Long Non-coding RNA Lnc712 Regulates Breast Cancer Cell Proliferation.
Breast Neoplasms
A multicenter trial evaluating retaspimycin HCL (IPI-504) plus trastuzumab in patients with advanced or metastatic HER2-positive breast cancer.
Breast Neoplasms
A Novel Agent Enhances the Chemotherapeutic Efficacy of Doxorubicin in MCF-7 Breast Cancer Cells.
Breast Neoplasms
A novel combination treatment for breast cancer cells involving BAPTA-AM and proteasome inhibitor bortezomib.
Breast Neoplasms
A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer.
Breast Neoplasms
A novel role for DYX1C1, a chaperone protein for both Hsp70 and Hsp90, in breast cancer.
Breast Neoplasms
A phase I trial of ganetespib in combination with paclitaxel and trastuzumab in patients with human epidermal growth factor receptor-2 (HER2)-positive metastatic breast cancer.
Breast Neoplasms
A phase I-II study of the histone deacetylase inhibitor vorinostat plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in locally advanced breast cancer.
Breast Neoplasms
A Phase II Open-Label Study of Ganetespib, a Novel Heat Shock Protein 90 Inhibitor for Patients With Metastatic Breast Cancer.
Breast Neoplasms
A phase II study of 17-allylamino-17-demethoxygeldanamycin in metastatic or locally advanced, unresectable breast cancer.
Breast Neoplasms
A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells.
Breast Neoplasms
Activation of mitochondrial unfolded protein response is associated with Her2-overexpression breast cancer.
Breast Neoplasms
Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2.
Breast Neoplasms
Additive viability-loss following hsp70/hsc70 double interference and Hsp90 inhibition in two breast cancer cell lines.
Breast Neoplasms
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers.
Breast Neoplasms
AIDing cancer treatment: Reducing AID activity via HSP90 inhibition.
Breast Neoplasms
Alkaloid derivative ION-31a inhibits breast cancer metastasis and angiogenesis by targeting HSP90?.
Breast Neoplasms
Alpha B crystallin expression in response to hormone, oncogenes and stress.
Breast Neoplasms
alphaB-crystallin is a marker of aggressive breast cancer behavior but does not independently predict for patient outcome: a combined analysis of two randomized studies.
Breast Neoplasms
AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer.
Breast Neoplasms
Altered molecular pathways decides the treatment outcome of Hsp90 inhibitors against breast cancer cells.
Breast Neoplasms
Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer.
Breast Neoplasms
An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.
Breast Neoplasms
An investigation of heat shock protein 27 and P-glycoprotein mediated multi-drug resistance in breast cancer using liquid chromatography-tandem mass spectrometry-based targeted proteomics.
Breast Neoplasms
Androgen receptor and heat shock protein 27 co-regulate the malignant potential of molecular apocrine breast cancer.
Breast Neoplasms
Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors.
Breast Neoplasms
Anti-tumor activity of the Hsp90 inhibitor IPI-504 in HER2 positive trastuzumab-resistant breast cancer.
Breast Neoplasms
Antibodies to heat shock protein 90 in osteosarcoma patients correlate with response to neoadjuvant chemotherapy.
Breast Neoplasms
Antibodies to heat-shock protein 27 are associated with improved survival in patients with breast cancer.
Breast Neoplasms
Anticancer effects of the Hsp90 inhibitor 17-demethoxy-reblastatin in human breast cancer MDA-MB-231 cells.
Breast Neoplasms
Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70.
Breast Neoplasms
Assessment of wastewater-irrigated soil containing heavy metals and establishment of specific biomarkers.
Breast Neoplasms
Associations of HSP90 client proteins in human breast cancer.
Breast Neoplasms
AT-533, a novel Hsp90 inhibitor, inhibits breast cancer growth and HIF-1?/VEGF/VEGFR-2-mediated angiogenesis in vitro and in vivo.
Breast Neoplasms
Autoantibodies to the 90kDa heat shock protein and poor survival in breast cancer patients.
Breast Neoplasms
Autophagy Blockade by Ai Du Qing Formula Promotes Chemosensitivity of Breast Cancer Stem Cells Via GRP78/?-Catenin/ABCG2 Axis.
Breast Neoplasms
BAG-1/SODD, HSP70 and HSP90 are potential prognostic markers of poor survival in node-negative breast carcinoma.
Breast Neoplasms
BAG-i expression in human breast cancer: interrelationship between BAG-1 RNA, protein, HSC70 expression and clinico-pathological data.
Breast Neoplasms
Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78.
Breast Neoplasms
BIK and GRP78 protein expression as possible markers of response to preoperative chemotherapy and survival in breast cancer.
Breast Neoplasms
Bioactivity-Guided Identification and Cell Signaling Technology to Delineate the Lactate Dehydrogenase A Inhibition Effects of Spatholobus suberectus on Breast Cancer.
Breast Neoplasms
Biochemical requirements for the expression of heat shock protein 72 kda in human breast cancer MCF-7 cells.
Breast Neoplasms
Biological and clinical significance of HER2 overexpression in breast cancer.
Breast Neoplasms
BJ-B11, an Hsp90 Inhibitor, Constrains the Proliferation and Invasion of Breast Cancer Cells.
Breast Neoplasms
Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response.
Breast Neoplasms
Blockage of conformational changes of heat shock protein gp96 on cell membrane by a ?-helix peptide inhibits HER2 dimerization and signaling in breast cancer.
Breast Neoplasms
Blocking HSF1 by dominant-negative mutant to sensitize tumor cells to hyperthermia.
Breast Neoplasms
Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER+ breast cancer cells.
Breast Neoplasms
Breast cancer and HSP90 inhibitors: is there a role beyond the HER2-positive subtype?
Breast Neoplasms
Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone.
Breast Neoplasms
C-terminal HSP90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Breast Neoplasms
Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.
Breast Neoplasms
Carbamazepine promotes Her-2 protein degradation in breast cancer cells by modulating HDAC6 activity and acetylation of Hsp90.
Breast Neoplasms
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands.
Breast Neoplasms
Cell Surface GRP78 Accelerated Breast Cancer Cell Proliferation and Migration by Activating STAT3.
Breast Neoplasms
Cell surface GRP78 and Dermcidin cooperate to regulate breast cancer cell migration through Wnt signaling.
Breast Neoplasms
Cell surface GRP78 promotes stemness in normal and neoplastic cells.
Breast Neoplasms
Cell surface GRP78: A potential marker of good prognosis and response to chemotherapy in breast cancer.
Breast Neoplasms
Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.
Breast Neoplasms
Chemotherapy Controls Metastasis Through Stimulatory Effects on GRP78 and Its Transcription Factor CREB3L1.
Breast Neoplasms
Chromatographic separation of eight progesterone receptor isoforms in human breast tumors, and detection by radioligand and monoclonal antibodies. Association with hsp90 and hsp70 heat shock proteins.
Breast Neoplasms
Co-expression of steroid receptors (estrogen receptor alpha and/or progesterone receptors) and Her-2/neu: Clinical implications.
Breast Neoplasms
Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters. Commentary re: P. Münster et al., Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. Clin. Cancer Res., 7: 2228-2236, 2001.
Breast Neoplasms
Comparison of Functional Proteomic Analyses of Human Breast Cancer Cell Lines T47D and MCF7.
Breast Neoplasms
Comparison of inhibitory effects of 17-AAG nanoparticles and free 17-AAG on HSP90 gene expression in breast cancer.
Breast Neoplasms
Constitutive overexpression of the 27,000 dalton heat shock protein in late passage human breast cancer cells.
Breast Neoplasms
Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.
Breast Neoplasms
Correlation of heat shock protein (HSP70) expression with cell proliferation (MIB1), estrogen receptors (ER) and clinicopathological variables in invasive ductal breast carcinomas.
Breast Neoplasms
Correlation of heat shock protein 70 expression with estrogen receptor levels in invasive human breast cancer.
Breast Neoplasms
Correlation of the protein expression of GRP78 and BIK/NBK with prognostic markers in patients with breast cancer and neoadjuvant chemotherapy.
Breast Neoplasms
Could Increased Expression of Hsp27, an "Anti-Inflammatory" Chaperone, Contribute to the Monocyte-Derived Dendritic Cell Bias towards Tolerance Induction in Breast Cancer Patients?
Breast Neoplasms
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.
Breast Neoplasms
DCZ3112, a novel Hsp90 inhibitor, exerts potent antitumor activity against HER2-positive breast cancer through disruption of Hsp90-Cdc37 interaction.
Breast Neoplasms
De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells.
Breast Neoplasms
De-regulation of GRP stress protein expression in human breast cancer cell lines.
Breast Neoplasms
Deciphering the Inhibition Mechanism of under Trial Hsp90 Inhibitors and Their Analogues: A Comparative Molecular Dynamics Simulation.
Breast Neoplasms
Design and synthesis of pyrimidinyl acyl thioureas as novel Hsp90 inhibitors in invasive ductal breast cancer and its bone metastasis.
Breast Neoplasms
Design of novel Geldanamycin analogue hsp90 alpha-inhibitor in silico for breast cancer therapy.
Breast Neoplasms
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors.
Breast Neoplasms
Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols bearing amino acid residues within the 3-amido motif as potent heat shock protein 90 (Hsp90) inhibitors.
Breast Neoplasms
Design, synthesis, and evaluation of a radicicol and geldanamycin chimera, radamide.
Breast Neoplasms
Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis.
Breast Neoplasms
Designed TPR modules as novel anticancer agents.
Breast Neoplasms
Destabilization of steroid receptors by heat shock protein 90-binding drugs: a ligand-independent approach to hormonal therapy of breast cancer.
Breast Neoplasms
Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C-terminal Inhibitors.
Breast Neoplasms
Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via ?-catenin/ABCG2 signaling.
Breast Neoplasms
Differential Expression of HSP90? in MDA-MB-231 and MCF-7 Cell Lines after Treatment with Doxorubicin.
Breast Neoplasms
Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients.
Breast Neoplasms
Discovery of a simplified deguelin analog as an HSP90 C-terminal inhibitor for HER2-positive breast cancer.
Breast Neoplasms
Discovery of diamine-linked 17-aroylamido-17-demethoxygeldanamycins as potent Hsp90 inhibitors.
Breast Neoplasms
Discovery of N-pyridoyl-?2 -pyrazolines as Hsp90 inhibitors.
Breast Neoplasms
Discovery of novel anti-breast cancer agents derived from deguelin as inhibitors of heat shock protein 90 (HSP90).
Breast Neoplasms
Distribution of Hsp-27 and HER-2/neu in in situ and invasive ductal breast carcinomas.
Breast Neoplasms
DNAJB6 governs a novel regulatory loop determining Wnt/?-catenin signalling activity.
Breast Neoplasms
Docosahexaenoic Acid-mediated Inhibition of Heat Shock Protein 90-p23 Chaperone Complex and Downstream Client Proteins in Lung and Breast Cancer.
Breast Neoplasms
Down-regulation of heat-shock protein 70 (HSP-70) correlated with responsiveness to neoadjuvant aromatase inhibitor therapy in breast cancer patients.
Breast Neoplasms
Down-regulation of RIP expression by 17-dimethylaminoethylamino-17-demethoxygeldanamycin promotes TRAIL-induced apoptosis in breast tumor cells.
Breast Neoplasms
Effects of exogenous human leptin on heat shock protein 70 expression in MCF-7 breast cancer cells and breast carcinoma of nude mice xenograft model.
Breast Neoplasms
Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer.
Breast Neoplasms
Elevated expression of nuclear Hsp90 in invasive breast tumors.
Breast Neoplasms
Elevated serum levels of heat shock protein 70 are associated with breast cancer.
Breast Neoplasms
Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer.
Breast Neoplasms
Endoplasmic reticulum stress-induced exosomal miR-27a-3p promotes immune escape in breast cancer via regulating PD-L1 expression in macrophages.
Breast Neoplasms
Eradication of breast cancer xenografts by hyperthermic suicide gene therapy under the control of the heat shock protein promoter.
Breast Neoplasms
Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter.
Breast Neoplasms
Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells.
Breast Neoplasms
Evaluation of Newcastle disease virus mediated dendritic cell activation and cross-priming tumor-specific immune responses ex vivo.
Breast Neoplasms
Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer.
Breast Neoplasms
Expression and roles of heat shock proteins in human breast cancer.
Breast Neoplasms
Expression of glucose-regulated protein 78 as prognostic biomarkers for triple-negative breast cancer.
Breast Neoplasms
Expression of heat shock protein 70 and c-myc protein in human breast cancer: an immunohistochemical study.
Breast Neoplasms
Expression of hsp90 and cyclin D1 in human breast cancer.
Breast Neoplasms
Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter.
Breast Neoplasms
Expression of the molecular chaperone ?B-crystallin in infiltrating ductal breast carcinomas and the significance thereof: an immunohistochemical and proteomics-based strategy.
Breast Neoplasms
Expression of tumor antigens and heat-shock protein 70 in breast cancer cells after high-intensity focused ultrasound ablation.
Breast Neoplasms
Extracellular heat shock protein (Hsp)70 and Hsp90? assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion.
Breast Neoplasms
Extragonadal teratocarcinoma in chimeric mice.
Breast Neoplasms
Flotillin depletion affects ErbB protein levels in different human breast cancer cells.
Breast Neoplasms
From Bacteria to Cancer: A Benzothiazole-Based DNA Gyrase B Inhibitor Redesigned for Hsp90 C-Terminal Inhibition.
Breast Neoplasms
Functional pathways shared by liver and lung metastases: a mitochondrial chaperone machine is up-regulated in soft-tissue breast cancer metastasis.
Breast Neoplasms
Functional proteomics of breast cancer for signal pathway profiling and target discovery.
Breast Neoplasms
FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation.
Breast Neoplasms
Ganetespib overcomes resistance to PARP inhibitors in breast cancer by targeting core proteins in the DNA repair machinery.
Breast Neoplasms
Ganetespib targets multiple levels of the receptor tyrosine kinase signaling cascade and preferentially inhibits ErbB2-overexpressing breast cancer cells.
Breast Neoplasms
Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma.
Breast Neoplasms
Glucose regulated protein 78 (GRP78) inhibits apoptosis and attentinutes chemosensitivity of gemcitabine in breast cancer cell via AKT/mitochondrial apoptotic pathway.
Breast Neoplasms
Glucose-regulated protein 78 as a novel effector of BRCA1 for inhibiting stress-induced apoptosis.
Breast Neoplasms
Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness.
Breast Neoplasms
Gp96 and its different expression in breast carcinomas.
Breast Neoplasms
GRP78 as a Novel Predictor of Responsiveness to Chemotherapy in Breast Cancer.
Breast Neoplasms
GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy.
Breast Neoplasms
GRP78 expression in peripheral blood mononuclear cells is a new predictive marker for the benefit of taxanes in breast cancer neoadjuvant treatment.
Breast Neoplasms
GRP78 mediates radiation resistance of a stem cell-like subpopulation within the MCF-7 breast cancer cell line.
Breast Neoplasms
GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer.
Breast Neoplasms
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
Breast Neoplasms
GRP94 overexpression as an indicator of unfavorable outcomes in breast cancer patients.
Breast Neoplasms
HBP21: A Novel Member of TPR Motif Family, as a Potential Chaperone of Heat Shock Protein 70 in Proliferative Vitreoretinopathy (PVR) and Breast Cancer.
Breast Neoplasms
Heat shock cognate 70 mutations in sporadic breast carcinoma.
Breast Neoplasms
Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells.
Breast Neoplasms
Heat shock protein 27 and gross cystic disease fluid protein 15 play critical roles in molecular apocrine breast cancer.
Breast Neoplasms
Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression.
Breast Neoplasms
Heat Shock Protein 27 Enhances SUMOylation of Heat Shock Protein B8 to Accelerate the Progression of Breast Cancer.
Breast Neoplasms
Heat shock protein 27 is associated with decreased survival in node-negative breast cancer patients.
Breast Neoplasms
Heat shock protein 27 overexpression in breast cancer lymph node metastasis.
Breast Neoplasms
Heat shock protein 27 plays two distinct roles in controlling human breast cancer cell migration on laminin-5.
Breast Neoplasms
Heat shock protein 27 protects against aminolevulinic acid-mediated photodynamic therapy-induced apoptosis and necrosis in human breast cancer cells.
Breast Neoplasms
Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer.
Breast Neoplasms
Heat shock protein 90 (hsp90) expression and breast cancer.
Breast Neoplasms
Heat Shock Protein 90 Family Isoforms as Prognostic Biomarkers and Their Correlations with Immune Infiltration in Breast Cancer.
Breast Neoplasms
Heat shock protein 90 is a rational molecular target in breast cancer.
Breast Neoplasms
Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3?/?-Catenin Signaling.
Breast Neoplasms
Heat shock protein 90? stabilizes focal adhesion kinase and enhances cell migration and invasion in breast cancer cells.
Breast Neoplasms
Heat shock protein as molecular targets for breast cancer therapeutics.
Breast Neoplasms
Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy.
Breast Neoplasms
Heat shock protein gp96 and CD4+ and CD8+ T-lymphocytes expression as prognostic factors in various molecular types of invasive breast carcinoma.
Breast Neoplasms
Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications.
Breast Neoplasms
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation.
Breast Neoplasms
Heat shock protein90 in lobular neoplasia of the breast.
Breast Neoplasms
Heat shock proteins in breast cancer progression--a suitable case for treatment?
Breast Neoplasms
Heat Shock Proteins: A Potential Anticancer Target.
Breast Neoplasms
Heat-shock protein 70 as a prognostic marker in node-negative breast cancer.
Breast Neoplasms
Her2 promotes early dissemination of breast cancer by suppressing the p38-MK2-Hsp27 pathway that is targetable by Wip1 inhibition.
Breast Neoplasms
HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer.
Breast Neoplasms
HER3-Mediated Resistance to Hsp90 Inhibition Detected in Breast Cancer Xenografts by Affibody-Based PET Imaging.
Breast Neoplasms
Heregulin up-regulates heat shock protein-70 expression in breast cancer cells.
Breast Neoplasms
HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer.
Breast Neoplasms
HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator.
Breast Neoplasms
High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics.
Breast Neoplasms
High HSP90 expression is associated with decreased survival in breast cancer.
Breast Neoplasms
High Level of Radiation-Induced Heat Shock Protein with a Molecular Weight of 27 and 70 kDa is the Hallmark of Radioresistant SP Cells of MCF-7 Breast Cancer Culture.
Breast Neoplasms
High Levels of Hsp90 Cochaperone p23 Promote Tumor Progression and Poor Prognosis in Breast Cancer by Increasing Lymph Node Metastases and Drug Resistance.
Breast Neoplasms
High risk for cardiovascular disease in postmenopausal breast cancer survivors.
Breast Neoplasms
HN1L promotes migration and invasion of breast cancer by up-regulating the expression of HMGB1.
Breast Neoplasms
Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors.
Breast Neoplasms
Hsp25 and Hsp70 in rodent tumors treated with doxorubicin and lovastatin.
Breast Neoplasms
Hsp27 expression in neuroblastoma: correlation with disease stage.
Breast Neoplasms
Hsp27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells.
Breast Neoplasms
Hsp27-induced MMP-9 expression is influenced by the Src tyrosine protein kinase yes.
Breast Neoplasms
Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells.
Breast Neoplasms
Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells.
Breast Neoplasms
HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models.
Breast Neoplasms
HSP90 expression and its association with wighteone metabolite response in HER2-positive breast cancer cells.
Breast Neoplasms
Hsp90 in the continuum of breast ductal carcinogenesis: Evaluation in precursors, preinvasive and ductal carcinoma lesions.
Breast Neoplasms
HSP90 Inhibition Is Effective in Breast Cancer: A Phase II Trial of Tanespimycin (17-AAG) Plus Trastuzumab in Patients with HER2-Positive Metastatic Breast Cancer Progressing on Trastuzumab.
Breast Neoplasms
Hsp90 Inhibition Results in Glucocorticoid Receptor Degradation in Association with Increased Sensitivity to Paclitaxel in Triple-Negative Breast Cancer.
Breast Neoplasms
Hsp90 inhibitor 17-AAG reduces ErbB2 levels and inhibits proliferation of the trastuzumab resistant breast tumor cell line JIMT-1.
Breast Neoplasms
HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates.
Breast Neoplasms
HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer.
Breast Neoplasms
HSP90 inhibitor AUY922 can reverse Fulvestrant induced feedback reaction in human breast cancer cells.
Breast Neoplasms
HSP90 inhibitor PU-H71 increases radiosensitivity of breast cancer cells metastasized to visceral organs and alters the levels of inflammatory mediators.
Breast Neoplasms
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models.
Breast Neoplasms
HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line.
Breast Neoplasms
Hsp90 inhibitor-loaded IR780 micelles for mitochondria-targeted mild-temperature photothermal therapy in xenograft models of human breast cancer.
Breast Neoplasms
Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.
Breast Neoplasms
Hsp90 Inhibitor; NVP-AUY922 in Combination with Doxorubicin Induces Apoptosis and Downregulates VEGF in MCF-7 Breast Cancer Cell Line.
Breast Neoplasms
Hsp90 inhibitors and drug resistance in cancer: The potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs.
Breast Neoplasms
HSP90 inhibitors decrease AID levels and activity in mice and in human cells.
Breast Neoplasms
Hsp90 inhibitors in breast cancer: A systematic review.
Breast Neoplasms
HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion.
Breast Neoplasms
Hsp90 molecular chaperone inhibitors: are we there yet?
Breast Neoplasms
Hsp90 regulates HDAC3-dependent gene transcription while HDAC3 regulates the functions of Hsp90.
Breast Neoplasms
Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.
Breast Neoplasms
HSP90, HSPA8, HIF-1 alpha and HSP70-2 polymorphisms in breast cancer: a case-control study.
Breast Neoplasms
Hsp90: A Global Regulator of the Genotype-to-Phenotype Map in Cancers.
Breast Neoplasms
Hsp90: a novel target for cancer therapy.
Breast Neoplasms
Hsp90: an emerging target for breast cancer therapy.
Breast Neoplasms
Hsp90? Mediates BMI1 Expression in Breast Cancer Stem/Progenitor Cells through Facilitating Nuclear Translocation of c-Myc and EZH2.
Breast Neoplasms
Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Heat Shock Protein 90 Overexpression, Ki67 Proliferative Index, and Topoisomerase II-? Co-amplification as Predictors of Pathologic Complete Response to Neoadjuvant Chemotherapy With Trastuzumab and Docetaxel.
Breast Neoplasms
Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70).
Breast Neoplasms
Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women.
Breast Neoplasms
Identification of a new scaffold for hsp90 C-terminal inhibition.
Breast Neoplasms
Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.
Breast Neoplasms
Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry.
Breast Neoplasms
Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library.
Breast Neoplasms
Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.
Breast Neoplasms
Identification of keratins 18, 19 and heat-shock protein 90 beta as candidate substrates of proteolysis during ionizing radiation-induced apoptosis of estrogen-receptor negative breast tumor cells.
Breast Neoplasms
IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironments.
Breast Neoplasms
IGFBP-3 sensitizes antiestrogen-resistant breast cancer cells through interaction with GRP78.
Breast Neoplasms
Immunization with Murine Breast Cancer Cells Treated with Antisense Oligodeoxynucleotides to Type I Insulin-Like Growth Factor Receptor Induced an Antitumoral Effect Mediated by a CD8+ Response Involving Fas/Fas Ligand Cytotoxic Pathway.
Breast Neoplasms
Improvement of protein immobilization for the elaboration of tumor-associated antigen microarrays: application to the sensitive and specific detection of tumor markers from breast cancer sera.
Breast Neoplasms
In silico design of small peptide-based Hsp90 inhibitor: A novel anticancer agent.
Breast Neoplasms
In vitro study comparing the efficacy of the water-soluble HSP90 inhibitors, 17-AEPGA and 17-DMAG, with that of the non?water-soluble HSP90 inhibitor, 17-AAG, in breast cancer cell lines.
Breast Neoplasms
Increased heat shock protein 70 (Hsp70) serum levels and low NK cell counts after radiotherapy - potential markers for predicting breast cancer recurrence?
Breast Neoplasms
Indolylkojyl methane analogue IKM5 potentially inhibits invasion of breast cancer cells via attenuation of GRP78.
Breast Neoplasms
Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors.
Breast Neoplasms
Induction of complete regressions of oncogene-induced breast tumors in mice.
Breast Neoplasms
Induction of Hsp22 (HspB8) by estrogen and the metalloestrogen cadmium in estrogen receptor-positive breast cancer cells.
Breast Neoplasms
Induction of the estrogen-regulated "24K" protein by heat shock.
Breast Neoplasms
Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.
Breast Neoplasms
Inhibition of 17beta-hydroxysteroid dehydrogenase type 7 modulates breast cancer protein profile and enhances apoptosis by down-regulating GRP78.
Breast Neoplasms
Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface Associated GRP78.
Breast Neoplasms
Inhibition of ezrin causes PKC?-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells.
Breast Neoplasms
Inhibition of heat shock protein (Hsp) 27 potentiates the suppressive effect of Hsp90 inhibitors in targeting breast cancer stem-like cells.
Breast Neoplasms
Inhibition of heat shock protein 27-mediated resistance to DNA damaging agents by a novel PKC delta-V5 heptapeptide.
Breast Neoplasms
Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells.
Breast Neoplasms
Inhibition of mitogen-activated protein kinase signaling pathway sensitizes breast cancer cells to endoplasmic reticulum stress-induced apoptosis.
Breast Neoplasms
Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients.
Breast Neoplasms
Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition.
Breast Neoplasms
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
Breast Neoplasms
Investigation of the role of quercetin as a heat shock protein inhibitor on apoptosis in human breast cancer cells.
Breast Neoplasms
Involvement of heat shock protein 27 in the susceptibility of KT human breast cancer cells to UVC and interferon lethality.
Breast Neoplasms
Is the small heat shock protein alphaB-crystallin an oncogene?
Breast Neoplasms
Isolation of a Novel Thioflavin S-Derived Compound that Inhibits BAG-1-Mediated Protein Interactions and Targets BRAF Inhibitor-Resistant Cell Lines.
Breast Neoplasms
KEGG-expressed genes and pathways in triple negative breast cancer: Protocol for a systematic review and data mining.
Breast Neoplasms
l-Peptide functionalized dual-responsive nanoparticles for controlled paclitaxel release and enhanced apoptosis in breast cancer cells.
Breast Neoplasms
Lack of association between tumor necrosis and hsp-27 expression in primary breast cancer.
Breast Neoplasms
Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity.
Breast Neoplasms
Leptin increases HER2 protein levels through a STAT3-mediated up-regulation of Hsp90 in breast cancer cells.
Breast Neoplasms
Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens.
Breast Neoplasms
Ligand-independent and agonist-mediated degradation of estrogen receptor-alpha in breast carcinoma cells: evidence for distinct degradative pathways.
Breast Neoplasms
Long non-coding RNA NKILA regulates expression of HSP90?, NF-?B and ?-catenin proteins in the MCF-7 breast cancer cell line.
Breast Neoplasms
Macrophage migration inhibitory factor involvement in breast cancer (Review).
Breast Neoplasms
Magnetic resonance spectroscopy detectable metabolomic fingerprint of response to antineoplastic treatment.
Breast Neoplasms
Magnetic thermoablation stimuli alter BCL2 and FGF-R1 but not HSP70 expression profiles in BT474 breast tumors.
Breast Neoplasms
Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition.
Breast Neoplasms
Measuring Tumor Epichaperome Expression Using [124I] PU-H71 Positron Emission Tomography as a Biomarker of Response for PU-H71 Plus Nab-Paclitaxel in HER2-Negative Metastatic Breast Cancer.
Breast Neoplasms
Medulloblastoma sensitivity to 17-allylamino-17-demethoxygeldanamycin requires MEK/ERKM.
Breast Neoplasms
Metabolism and Excretion of 6-Chloro-9-(4-methoxy-3,5-dimethylpyridin-2-ylmethyl)-9H-purin-2-ylamine (BIIB021), an HSP90 Inhibitor, in Rats and Dogs, and Assessment of its Metabolic Profile in Plasma of Humans.
Breast Neoplasms
Metastasis and the Tumor Microenvironment: A Joint Metastasis Research Society-AACR Conference - Research on Metastasis: Part 2.
Breast Neoplasms
Metformin inhibits proliferation and promotes apoptosis of HER2 positive breast cancer cells by downregulating HSP90.
Breast Neoplasms
MHC-class-I expression in human breast cancer correlates with nuclear localization of the 90 kDa heat-shock-protein.
Breast Neoplasms
MicroRNAs and Heat Shock Proteins in Breast Cancer Biology.
Breast Neoplasms
Mitochondrial autophagosomes as a mechanism of drug resistance in breast carcinoma.
Breast Neoplasms
Mitotic catastrophe cell death induced by heat shock protein 90 inhibitor in BRCA1-deficient breast cancer cell lines.
Breast Neoplasms
Modeling spheroid growth, PET tracer uptake, and treatment effects of the Hsp90 inhibitor NVP-AUY922.
Breast Neoplasms
Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer.
Breast Neoplasms
Modulation of expression of heat shock proteins and apoptosis by Flueggea leucopyrus (Willd) decoction in three breast cancer phenotypes.
Breast Neoplasms
Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001.
Breast Neoplasms
Molecular chaperones in mammary cancer growth and breast tumor therapy.
Breast Neoplasms
Molecular pathways: targeting hsp90--who benefits and who does not.
Breast Neoplasms
Molecular signature of response and potential pathways related to resistance to the HSP90 inhibitor, 17AAG, in breast cancer.
Breast Neoplasms
Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits.
Breast Neoplasms
Mortalin antibody-conjugated quantum dot transfer from human mesenchymal stromal cells to breast cancer cells requires cell-cell interaction.
Breast Neoplasms
Mortalin maintains breast cancer stem cells stemness via activation of Wnt/GSK3?/?-catenin signaling pathway.
Breast Neoplasms
Mortalin promotes breast cancer malignancy.
Breast Neoplasms
Multiclass comparative virtual screening to identify novel Hsp90 inhibitors: a therapeutic breast cancer drug target.
Breast Neoplasms
Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer.
Breast Neoplasms
Natural compounds as potential Hsp90 inhibitors for breast cancer-Pharmacophore guided molecular modelling studies.
Breast Neoplasms
Natural state of mutant p53 protein and heat shock protein 70 in breast cancer tissues.
Breast Neoplasms
Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-?-catenin signaling in breast cancer.
Breast Neoplasms
Neratinib induces ErbB2 ubiquitylation and endocytic degradation via HSP90 dissociation in breast cancer cells.
Breast Neoplasms
New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90.
Breast Neoplasms
NHF-derived carbon dots: prevalidation approach in breast cancer treatment.
Breast Neoplasms
Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells.
Breast Neoplasms
Non-Benzoquinone Geldanamycin Analog, WK-88-1, Induces Apoptosis in Human Breast Cancer Cell Lines.
Breast Neoplasms
Novel C-terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self-renewal, and epithelial-mesenchymal transition.
Breast Neoplasms
Novel Hsp90 inhibitor FW-04-806 displays potent antitumor effects in HER2-positive breast cancer cells as a single agent or in combination with lapatinib.
Breast Neoplasms
Novel Mechanism of Anti-apoptotic Function of 78-kDa Glucose-regulated Protein (GRP78): ENDOCRINE RESISTANCE FACTOR IN BREAST CANCER, THROUGH RELEASE OF B-CELL LYMPHOMA 2 (BCL-2) FROM BCL-2-INTERACTING KILLER (BIK).
Breast Neoplasms
Novel nuclear matrix protein HET binds to and influences activity of the HSP27 promoter in human breast cancer cells.
Breast Neoplasms
Novobiocin decreases SMYD3 expression and inhibits the migration of MDA-MB-231 human breast cancer cells.
Breast Neoplasms
NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models.
Breast Neoplasms
Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2?/ATF4/CHOP pathway in breast cancer.
Breast Neoplasms
Optical and radioiodinated tethered hsp90 inhibitors reveal selective internalization of ectopic hsp90 in malignant breast tumor cells.
Breast Neoplasms
Optical imaging with her2-targeted affibody molecules can monitor hsp90 treatment response in a breast cancer xenograft mouse model.
Breast Neoplasms
Osteopontin increases breast cancer cell sensitivity to specific signaling pathway inhibitors in preclinical models.
Breast Neoplasms
Ovarian Serous Carcinoma With a Novel HSP90AB1 Mutation in a Patient With Synchronous Primary Fallopian Tube Serous Carcinoma.
Breast Neoplasms
Overexpression of molecular chaperons GRP78 and GRP94 in CD44(hi)/CD24(lo) breast cancer stem cells.
Breast Neoplasms
Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions.
Breast Neoplasms
P-Cadherin and beta-catenin are useful prognostic markers in breast cancer patients; beta-catenin interacts with heat shock protein Hsp27.
Breast Neoplasms
p53 protein accumulation detected by five different antibodies: relationship to prognosis and heat shock protein 70 in breast cancer.
Breast Neoplasms
Paclitaxel-doxorubicin sequence is more effective in breast cancer cells with heat shock protein 27 overexpression.
Breast Neoplasms
Patient-derived heavy chain antibody targets cell surface HSP90 on breast tumors.
Breast Neoplasms
PCDHGB7 Increases Chemosensitivity to Carboplatin by Inhibiting HSPA9 via Inducing Apoptosis in Breast Cancer.
Breast Neoplasms
Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo.
Breast Neoplasms
PGK1-coupled HSP90 stabilizes GSK3? expression to regulate the stemness of breast cancer stem cells.
Breast Neoplasms
Phage display derived human monoclonal antibodies isolated by binding to the surface of live primary breast cancer cells recognize GRP78.
Breast Neoplasms
Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells.
Breast Neoplasms
Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2-positive breast cancer patients who have progressed on trastuzumab-based regimen.
Breast Neoplasms
Phase I-II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo.
Breast Neoplasms
Plumbagin sensitizes breast cancer cells to tamoxifen-induced cell death through GRP78 inhibition and Bik upregulation.
Breast Neoplasms
PNSA, a Novel C-Terminal Inhibitor of HSP90, Reverses Epithelial-Mesenchymal Transition and Suppresses Metastasis of Breast Cancer Cells In Vitro.
Breast Neoplasms
Polymorphism in the tumor necrosis factor-alpha promotor region and in the heat shock protein 70 genes associated with malignant tumors.
Breast Neoplasms
Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers.
Breast Neoplasms
Potential Prognostic Value of Histone Deacetylase 6 and Acetylated Heat-Shock Protein 90 in Early-Stage Breast Cancer.
Breast Neoplasms
Practical p-value adjustment for optimally selected cutpoints.
Breast Neoplasms
PRDM14 directly interacts with heat shock proteins HSP90? and glucose-regulated protein 78.
Breast Neoplasms
Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers.
Breast Neoplasms
Prodigiosin activates endoplasmic reticulum stress cell death pathway in human breast carcinoma cell lines.
Breast Neoplasms
Prognostic evaluation of oestrogen-regulated protein immunoreactivity in ductal invasive (NOS) breast cancer.
Breast Neoplasms
Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer.
Breast Neoplasms
Prognostic significance of GRP78 expression patterns in breast cancer patients receiving adjuvant chemotherapy.
Breast Neoplasms
Prognostic significance of heat shock protein 90AA1 (HSP90?) in invasive breast cancer.
Breast Neoplasms
Progression of the role of CRYAB in signaling pathways and cancers.
Breast Neoplasms
Proliferating cell nuclear antigen and heat shock protein 70 immunolocalization in invasive ductal breast cancer not otherwise specified.
Breast Neoplasms
Proteomic characterization of differentially expressed proteins in breast cancer: Expression of hnRNP H1, RKIP and GRP78 is strongly associated with HER-2/neu status.
Breast Neoplasms
Proteomic detection of changes in protein synthesis induced by fibroblast growth factor-2 in MCF-7 human breast cancer cells.
Breast Neoplasms
Proteomic identification of heat shock protein 90 as a candidate target for p53 mutation reactivation by PRIMA-1 in breast cancer cells.
Breast Neoplasms
Proteomics of breast cancer for marker discovery and signal pathway profiling.
Breast Neoplasms
Proteomics of breast cancer: outcomes and prospects.
Breast Neoplasms
Proteomics-based identification of HSP60 as a tumor-associated antigen in early stage breast cancer and ductal carcinoma in situ.
Breast Neoplasms
PTHrP [67-86] regulates the expression of stress proteins in breast cancer cells inducing modifications in urokinase-plasminogen activator and MMP-1 expression.
Breast Neoplasms
Purification and characterisation of the breast cancer metastasis suppressor, BRMS1.
Breast Neoplasms
Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells.
Breast Neoplasms
Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
Breast Neoplasms
Radiofrequency hyperthermia promotes the therapeutic effects on chemotherapeutic-resistant breast cancer when combined with heat shock protein promoter-controlled HSV-TK gene therapy: Toward imaging-guided interventional gene therapy.
Breast Neoplasms
Radiosynthesis, biological evaluation and preliminary microPET study of 18F-labeled 5-resorcinolic triazolone derivative based on ganetespib targeting HSP90.
Breast Neoplasms
Ratio of proliferation markers and HSP90 gene expression as a predictor of pathological complete response in breast cancer neoadjuvant chemotherapy.
Breast Neoplasms
Recent advances in systemic therapy: Advances in systemic therapy for HER2-positive metastatic breast cancer.
Breast Neoplasms
Recent trends in microRNA research into breast cancer with particular focus on the associations between microRNAs and intrinsic subtypes.
Breast Neoplasms
Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer.
Breast Neoplasms
Regulation of heat shock protein 72 kDa and 90 kDa in human breast cancer MDA-MB-231 cells.
Breast Neoplasms
Relationship Between HSP70 and ERBB2 Expression in Breast Cancer Cell Lines Regarding Drug Resistance.
Breast Neoplasms
Relationship between the expression of phosphorylated heat shock protein beta-1 with lymph node metastases of breast cancer.
Breast Neoplasms
Research resource: enhanced genome-wide occupancy of estrogen receptor ? by the cochaperone p23 in breast cancer cells.
Breast Neoplasms
Response of human breast cancer cells to heat shock and chemotherapeutic drugs.
Breast Neoplasms
Role of BRCA1 in heat shock response.
Breast Neoplasms
Role of estrogen receptor/Sp1 complexes in estrogen-induced heat shock protein 27 gene expression.
Breast Neoplasms
Role of GRP78 in promoting therapeutic-resistant breast cancer.
Breast Neoplasms
Role of HSP90 in mediating cross-talk between the estrogen receptor and the Ah receptor signal transduction pathways.
Breast Neoplasms
Search for Hsp90 Inhibitors with Potential Anticancer Activity: Isolation and SAR Studies of Radicicol and Monocillin I from Two Plant-Associated Fungi of the Sonoran Desert(1).
Breast Neoplasms
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.
Breast Neoplasms
Sensitivity of flow cytometric assay for measurement of human intracellular heat shock protein 27.
Breast Neoplasms
Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1.
Breast Neoplasms
Serological detection of heat shock protein hsp27 in normal and breast cancer patients.
Breast Neoplasms
Serum antibodies to the 27-kd heat shock protein in women with gynecologic cancers.
Breast Neoplasms
Short peptides derived from the BAG-1 C-terminus inhibit the interaction between BAG-1 and HSC70 and decrease breast cancer cell growth.
Breast Neoplasms
Short-hairpin RNA-mediated Heat shock protein 90 gene silencing inhibits human breast cancer cell growth in vitro and in vivo.
Breast Neoplasms
Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell.
Breast Neoplasms
Simultaneous quantification of protein phosphorylation sites using liquid chromatography-tandem mass spectrometry-based targeted proteomics: a linear algebra approach for isobaric phosphopeptides.
Breast Neoplasms
SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells.
Breast Neoplasms
Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors.
Breast Neoplasms
Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells.
Breast Neoplasms
Stereospecific antitumor activity of radicicol oxime derivatives.
Breast Neoplasms
Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis.
Breast Neoplasms
Structural insights into tumor-specific chaperoning activity of gamma synuclein in protecting estrogen receptor alpha 36 and its role in tamoxifen resistance in breast cancer.
Breast Neoplasms
Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors.
Breast Neoplasms
Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer.
Breast Neoplasms
Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis.
Breast Neoplasms
Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide.
Breast Neoplasms
Synergistic Activity of the HSP90 Inhibitor Ganetespib With Lapatinib Reverses Acquired Lapatinib Resistance in HER2-Positive Breast Cancer Cells.
Breast Neoplasms
Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70.
Breast Neoplasms
Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90).
Breast Neoplasms
Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90.
Breast Neoplasms
Synthesis of novel dual target inhibitors of PARP and HSP90 and their antitumor activities.
Breast Neoplasms
Systematic analyses of key genes and pathways in the development of invasive breast cancer.
Breast Neoplasms
Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction.
Breast Neoplasms
Tamoxifen-induced cytotoxicity in breast cancer cells is mediated by glucose-regulated protein 78 (GRP78) via AKT (Thr308) regulation.
Breast Neoplasms
Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes.
Breast Neoplasms
Targeted Therapies in Breast Cancer: Implications for Advanced Oncology Practice.
Breast Neoplasms
Targeted therapy for breast cancer.
Breast Neoplasms
Targeting GRP78 and antiestrogen resistance in breast cancer.
Breast Neoplasms
Targeting highly expressed extracellular HSP90 in breast cancer stem cells inhibits tumor growth in vitro and in vivo.
Breast Neoplasms
Targeting HSP90 Gene Expression with 17-DMAG Nanoparticles in Breast Cancer Cells.
Breast Neoplasms
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition.
Breast Neoplasms
Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells.
Breast Neoplasms
Targeting on glycosylation of mutant FLT3 in acute myeloid leukemia.
Breast Neoplasms
Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis.
Breast Neoplasms
The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG.
Breast Neoplasms
The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells.
Breast Neoplasms
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast.
Breast Neoplasms
The COOH-Terminal Proline-Rich Region of GRP78 Is a Key Regulator of Its Cell Surface Expression and Viability of Tamoxifen-Resistant Breast Cancer Cells.
Breast Neoplasms
The design, synthesis, and evaluation of coumarin ring derivatives of the novobiocin scaffold that exhibit antiproliferative activity.
Breast Neoplasms
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Breast Neoplasms
The effects of Hsp90 expression alteration on spinal metastases of breast carcinoma.
Breast Neoplasms
The emergence of targeted drugs in breast cancer to prevent resistance to endocrine treatment and chemotherapy.
Breast Neoplasms
The endoplasmic reticulum stress markers GRP78 and CHOP predict disease-free survival and responsiveness to chemotherapy in breast cancer.
Breast Neoplasms
The flavonoid TL-2-8 induces cell death and immature mitophagy in breast cancer cells via abrogating the function of the AHA1/Hsp90 complex.
Breast Neoplasms
The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of AKT in ErbB2 overexpressing breast cancer cells.
Breast Neoplasms
The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line.
Breast Neoplasms
The HSP-RTK-Akt axis mediates acquired resistance to Ganetespib in HER2-positive breast cancer.
Breast Neoplasms
The HSP90 inhibitor NVP-AUY922 inhibits growth of HER2 positive and trastuzumab-resistant breast cancer cells.
Breast Neoplasms
The in vitro immunogenic potential of caspase-3 proficient breast cancer cells with basal low immunogenicity is increased by hypofractionated irradiation.
Breast Neoplasms
The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide.
Breast Neoplasms
The non-DNA-binding heterooligomeric form of mammalian steroid hormone receptors contains a hsp90-bound 59-kilodalton protein.
Breast Neoplasms
The overexpression of Hsp90B1 is associated with tumorigenesis of canine mammary glands.
Breast Neoplasms
The phosphorylation-specific association of STMN1 with GRP78 promotes breast cancer metastasis.
Breast Neoplasms
The potential role of HSP70 as an indicator of response to radiation and hyperthermia treatments for recurrent breast cancer.
Breast Neoplasms
The Prognostic Significance of Hsp70/Hsp90 Expression in Breast Cancer: A Systematic Review and Meta-analysis.
Breast Neoplasms
The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells.
Breast Neoplasms
The small heat shock protein hsp27 increases invasiveness but decreases motility of breast cancer cells.
Breast Neoplasms
The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines.
Breast Neoplasms
The small heat shock protein HSP27 is not an independent prognostic marker in axillary lymph node-negative breast cancer patients.
Breast Neoplasms
Tid1, CHIP and ErbB2 interactions and their prognostic implications for breast cancer patients.
Breast Neoplasms
Tissue microarray analysis of FAS, Bcl-2, Bcl-x, ER, PgR, Hsp60, p53 and Her2-neu in breast carcinoma.
Breast Neoplasms
Tomm34 is commonly expressed in epithelial ovarian cancer and associates with tumour type and high FIGO stage.
Breast Neoplasms
Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes.
Breast Neoplasms
Treatment with panobinostat induces glucose-regulated protein 78 acetylation and endoplasmic reticulum stress in breast cancer cells.
Breast Neoplasms
Triple-negative breast cancer: novel therapies and new directions.
Breast Neoplasms
Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90-Targeted Therapy.
Breast Neoplasms
Tunicamycin-induced ER stress in breast cancer cells neither expresses GRP78 on the surface nor secretes it into the media.
Breast Neoplasms
UBR1 promotes protein kinase quality control and sensitizes cells to Hsp90 inhibition.
Breast Neoplasms
Understanding the sources of errors in ex vivo Hsp90 molecular imaging for rapid-on-site breast cancer diagnosis.
Breast Neoplasms
Up-regulation of cathepsin S expression by HSP90 and 5-HT7 receptor-dependent serotonin signaling correlates with triple negativity of human breast cancer.
Breast Neoplasms
Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.
Breast Neoplasms
Using a xenograft model of human breast cancer metastasis to find genes associated with clinically aggressive disease.
Breast Neoplasms
USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer.
Breast Neoplasms
Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment.
Breast Neoplasms
VIP-grafted sterically stabilized phospholipid nanomicellar 17-allylamino-17-demethoxy geldanamycin: a novel targeted nanomedicine for breast cancer.
Breast Neoplasms
Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer.
Breast Neoplasms
Visualizing and Quantifying the Effect of the Inhibition of HSP70 on Breast Cancer Cells Based on Laser Scanning Microscopy.
Breast Neoplasms
Why Is This Effective HSP90 Inhibitor Not Being Developed in HER2+ Breast Cancer?
Breast Neoplasms
Withanolides-induced breast cancer cell death is correlated with their ability to inhibit heat protein 90.
Breast Neoplasms
X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition.
Breast Neoplasms
[Diagnostic and Therapeutic Potential of Membrane HSP90].
Breast Neoplasms
[Effect of anacardic acid, a Hsp90 inhibitor, on proliferation, invasion and migration of breast cancer MDA-MB-231 cells].
Breast Neoplasms
[Effect of HSP90 function inhibited on the telomerase and P53 mutant in breast cancer cells]
Breast Neoplasms
[Impact of HSP90 Inhibition on Viability and Cell Cycle in Relation to p53 Status].
Breast Neoplasms
[Preliminary study of effect of antisense hsc70 effect on the stability of mutant p53 protein]
Breast Neoplasms
[The role of the heat shock protein in human breast cancer]
Bronchiolitis
Lack of protection in mice and necrotizing bronchointerstitial pneumonia with bronchiolitis in guinea pigs immunized with vaccines directed against the hsp60 molecule of Mycobacterium tuberculosis.
Bronchiolitis Obliterans
Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis.
Bronchiolitis Obliterans
The role of heat shock protein 27 in bronchiolitis obliterans syndrome after lung transplantation.
Bronchitis
Heat shock protein 70 in lung and kidney of specific-pathogen-free chickens is a receptor-associated protein that interacts with the binding domain of the spike protein of infectious bronchitis virus.
Bronchitis
Heat Shock Protein Member 8 Is an Attachment Factor for Infectious Bronchitis Virus.
Bronchitis, Chronic
Glucocorticoid receptors in bronchial epithelial cells in asthma.
Bronchitis, Chronic
Heat shock proteins mRNA expressions by peripheral blood mononuclear cells in asthma and chronic bronchitis.
Bronchitis, Chronic
Increased expression of heat shock protein 70 on airway cells in asthma and chronic bronchitis.
Bronchopulmonary Dysplasia
Heat Shock Protein-70 Levels Are Associated With a State of Oxidative Damage in the Development of Bronchopulmonary Dysplasia.
Bronchopulmonary Dysplasia
Treatment with Geranylgeranylacetone Induces Heat Shock Protein 70 and Attenuates Neonatal Hyperoxic Lung Injury in a Model of Bronchopulmonary Dysplasia.
Bronchopulmonary Dysplasia
[Effect of glucose regulated protein 78 gene silencing on hyperoxia-induced apoptosis in alveolar epithelial cells].
Brucellosis
Cellular prion protein promotes Brucella infection into macrophages.
Brucellosis
Characterization of the main immunogenic proteins in Brucella infection for their application in diagnosis of brucellosis.
Brucellosis
Comparison of heat shock response in Brucella abortus and Brucella melitensis.
Brucellosis
Immunoblot studies in the differential diagnosis of porcine brucellosis: an immunodominant 62 kDa protein is related to the mycobacterial 65 kDa heat shock protein (HSP-65).
Brucellosis
Molecular cloning and nucleotide sequence analysis of the gene encoding the immunoreactive Brucella abortus Hsp60 protein, BA60K.
Brucellosis
Role of immune responses to a GroEL heat shock protein in preventing brucellosis in mice vaccinated with Brucella abortus strain RB51.
Bulbo-Spinal Atrophy, X-Linked
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.
Bulbo-Spinal Atrophy, X-Linked
17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.
Bulbo-Spinal Atrophy, X-Linked
Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).
Bulbo-Spinal Atrophy, X-Linked
Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein.
Bulbo-Spinal Atrophy, X-Linked
Hsp40 molecules that target to the ubiquitin-proteasome system decrease inclusion formation in models of polyglutamine disease.
Bulbo-Spinal Atrophy, X-Linked
Hsp40 Molecules That Target to the Ubiquitin-proteasome System Decrease Inclusion Formation in Models of Polyglutamine Disease.
Bulbo-Spinal Atrophy, X-Linked
Inhibition of Hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation.
Bulbo-Spinal Atrophy, X-Linked
Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases.
Bulbo-Spinal Atrophy, X-Linked
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Burkitt Lymphoma
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Burkitt Lymphoma
Heat shock protein 70 (Hsp70)-stimulated deoxycytidine deaminases from a human lymphoma cell but not the activation-induced cytidine deaminase (AID) from Ramos 6.4 human Burkitt's lymphoma cells.
Burkitt Lymphoma
HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling.
Burkitt Lymphoma
Human peripheral gamma delta T cells recognize hsp60 molecules on Daudi Burkitt's lymphoma cells.
Burkitt Lymphoma
Immunoelectron microscopic localization of the 60-kDa heat shock chaperonin protein (Hsp60) in mammalian cells.
Burkitt Lymphoma
Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma.
Burkitt Lymphoma
Recognition by human V gamma 9/V delta 2 T cells of a GroEL homolog on Daudi Burkitt's lymphoma cells.
Burkitt Lymphoma
Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition.
Buruli Ulcer
Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans.
Caliciviridae Infections
Molecular chaperone Hsp90 is a therapeutic target for noroviruses.
Candidiasis
A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis.
Candidiasis
Acquired immunity to systemic candidiasis in immunodeficient mice: role of antibody to heat-shock protein 90.
Candidiasis
Antibodies against Candida: potential therapeutics?
Candidiasis
Antifungal antibodies: a new approach to the treatment of systemic candidiasis.
Candidiasis
Chitosan hydrogel loaded with recombinant protein containing epitope C from HSP90 of Candida albicans induces protective immune responses against systemic candidiasis.
Candidiasis
Circulating heat shock proteins in women with a history of recurrent vulvovaginitis.
Candidiasis
Comparison of protective effect of protein and DNA vaccines hsp90 in murine model of systemic candidiasis.
Candidiasis
COVID19 associated mucormycosis: Is GRP78 a possible link?
Candidiasis
Differential Gene Expression of Heat Shock Protein 90 (Hsp90) of Candida albicans obtained from Malaysian and Iranian Patients.
Candidiasis
Direct effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence of Candida and Aspergillus species.
Candidiasis
Dose range evaluation of Mycograb C28Y variant, a human recombinant antibody fragment to heat shock protein 90, in combination with amphotericin B-desoxycholate for treatment of murine systemic candidiasis.
Candidiasis
Genetically recombinant antibodies: new therapeutics against candidiasis.
Candidiasis
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.
Candidiasis
Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.
Candidiasis
Metallochelating liposomes with associated lipophilised norAbuMDP as biocompatible platform for construction of vaccines with recombinant His-tagged antigens: Preparation, structural study and immune response towards rHsp90.
Candidiasis
Preliminary assessment of a human recombinant antibody fragment to hsp90 in murine invasive candidiasis.
Candidiasis
Production of antibodies to antigens of Candida albicans in CBA/H mice.
Candidiasis
Protective immune responses against systemic candidiasis mediated by phage-displayed specific epitope of Candida albicans heat shock protein 90 in C57BL/6J mice.
Candidiasis
Systemic and mucosal immunization with Candida albicans hsp90 elicits hsp90-specific humoral response in vaginal mucosa which is further enhanced during experimental vaginal candidiasis.
Candidiasis
The non-Geldanamycin Hsp90 inhibitors enhanced the antifungal activity of fluconazole.
Candidiasis
The use of hybrid phage displaying antigen epitope and recombinant protein in the diagnosis of systemic Candida albicans infection in rabbits and cancer patients.
Candidiasis, Invasive
A Randomized, Blinded, Multicenter Trial of Lipid-Associated Amphotericin B Alone versus in Combination with an Antibody-Based Inhibitor of Heat Shock Protein 90 in Patients with Invasive Candidiasis.
Candidiasis, Invasive
An antibody reactivity-based assay for diagnosis of invasive candidiasis using protein array.
Candidiasis, Invasive
Efungumab and caspofungin: pre-clinical data supporting synergy.
Candidiasis, Invasive
Efungumab: A Novel Agent in the Treatment of Invasive Candidiasis (November).
Candidiasis, Invasive
Fungal antigens expressed during invasive aspergillosis.
Candidiasis, Invasive
Potential of anti-Candida antibodies in immunoprophylaxis.
Candidiasis, Invasive
Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90.
Candidiasis, Invasive
Preliminary assessment of a human recombinant antibody fragment to hsp90 in murine invasive candidiasis.
Candidiasis, Invasive
Prophylactic vaccination with phage-displayed epitope of C. albicans elicits protective immune responses against systemic candidiasis in C57BL/6 mice.
Candidiasis, Invasive
Recombinant antibodies: a natural partner in combinatorial antifungal therapy.
Candidiasis, Invasive
Serum antibody signature directed against Candida albicans Hsp90 and enolase detects invasive candidiasis in non-neutropenic patients.
Candidiasis, Invasive
The use of hybrid phage displaying antigen epitope and recombinant protein in the diagnosis of systemic Candida albicans infection in rabbits and cancer patients.
Capsule Opacification
HSP90 as a novel therapeutic target for posterior capsule opacification.
Carcinogenesis
(1)H, (15)N and (13)C backbone resonance assignments of the TPR1 and TPR2A domains of mouse STI1.
Carcinogenesis
17-AAG: mechanisms of antitumour activity.
Carcinogenesis
17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells.
Carcinogenesis
17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.
Carcinogenesis
60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis.
Carcinogenesis
A fluorescence polarization assay for inhibitors of Hsp90.
Carcinogenesis
A Mechanistic and Structural Analysis of the Inhibition of Heat Shock Protein 90 by the Benzoquinone and Hydroquinone Ansamycins.
Carcinogenesis
A novel DNA vaccine constructed by heat shock protein 70 and melanoma antigen-encoding gene 3 against tumorigenesis.
Carcinogenesis
A potential role for Helicobacter pylori heat shock protein 60 in gastric tumorigenesis.
Carcinogenesis
Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis.
Carcinogenesis
Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox.
Carcinogenesis
Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat.
Carcinogenesis
Acute acidification or amiloride treatment suppresses the ability of Hsp70 to inhibit heat-induced apoptosis.
Carcinogenesis
Altered Hsp90 function in cancer: a unique therapeutic opportunity.
Carcinogenesis
Androgen Receptor Protein Levels Are Significantly Reduced in Serous Ovarian Carcinomas Compared with Benign or Borderline Disease but Are Not altered by Cancer Stage or Metastatic Progression.
Carcinogenesis
Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers.
Carcinogenesis
Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins.
Carcinogenesis
Anti-HIV agent MAP30 modulates the expression profile of viral and cellular genes for proliferation and apoptosis in AIDS-related lymphoma cells infected with Kaposi's sarcoma-associated virus.
Carcinogenesis
Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-?B and Nrf2 Signaling Pathways.
Carcinogenesis
Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.
Carcinogenesis
Anticancer activity of methylene blue via inhibition of heat shock protein 70.
Carcinogenesis
Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies.
Carcinogenesis
Association between Alpha B-crystallin expression and prognosis in patients with solid tumors: A protocol for systematic review and meta-analysis.
Carcinogenesis
AT-533, a novel Hsp90 inhibitor, inhibits breast cancer growth and HIF-1?/VEGF/VEGFR-2-mediated angiogenesis in vitro and in vivo.
Carcinogenesis
ATM is the primary kinase responsible for phosphorylation of Hsp90? after ionizing radiation.
Carcinogenesis
ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation.
Carcinogenesis
Blockage of HSP 90 modulates Helicobacter pylori-induced IL-8 productions through the inactivation of transcriptional factors of AP-1 and NF-kappaB.
Carcinogenesis
Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.
Carcinogenesis
Can The Lack of HSP90alpha Protein in Brain Normal Tissue and Cell Lines, Rationalise it as a Possible Therapeutic Target for Gliomas?
Carcinogenesis
CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.
Carcinogenesis
Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy.
Carcinogenesis
Cell surface GRP78 promotes stemness in normal and neoplastic cells.
Carcinogenesis
Chaperone-dependent stabilization and degradation of p53 mutants.
Carcinogenesis
Characterization and prognostic significance of mortalin, Bcl-2 and Bax in intrahepatic cholangiocarcinoma.
Carcinogenesis
Chemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance.
Carcinogenesis
Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone.
Carcinogenesis
Comparative analysis of Hsp10 and Hsp90 expression in healthy mucosa and adenocarcinoma of the large bowel.
Carcinogenesis
Cripto haploinsufficiency affects in vivo colon tumor development.
Carcinogenesis
Cripto stabilizes GRP78 on the cell membrane.
Carcinogenesis
Cytoplasmic expression of pontin in renal cell carcinoma correlates with tumor invasion, metastasis and patients' survival.
Carcinogenesis
Decreased expression of heat shock protein 20 in colorectal cancer and its implication in tumorigenesis.
Carcinogenesis
Detecting Posttranslational Modifications of Hsp90.
Carcinogenesis
Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Carcinogenesis
Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models.
Carcinogenesis
Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis.
Carcinogenesis
Differential expression of heat shock protein 90 isoforms in small cell lung cancer.
Carcinogenesis
Differential expression of hsp90, gelsolin and gst-pi in human gastric-carcinoma cell-lines.
Carcinogenesis
Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives.
Carcinogenesis
Direct targeting of HSP90 with daurisoline destabilizes ?-catenin to suppress lung cancer tumorigenesis.
Carcinogenesis
Discorhabdin N, a South African Natural Compound, for Hsp72 and Hsc70 Allosteric Modulation: Combined Study of Molecular Modeling and Dynamic Residue Network Analysis.
Carcinogenesis
Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90.
Carcinogenesis
Docosahexaenoic Acid-mediated Inhibition of Heat Shock Protein 90-p23 Chaperone Complex and Downstream Client Proteins in Lung and Breast Cancer.
Carcinogenesis
Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway.
Carcinogenesis
Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma.
Carcinogenesis
Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Carcinogenesis
Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence.
Carcinogenesis
Druggability of Mortalin for Cancer and Neuro-Degenerative Disorders.
Carcinogenesis
Dual role of heat shock proteins as regulators of apoptosis and innate immunity.
Carcinogenesis
Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis.
Carcinogenesis
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice.
Carcinogenesis
Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.
Carcinogenesis
Endoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis.
Carcinogenesis
Esophageal cancer alters the expression of nuclear pore complex binding protein Hsc70 and eIF5A-1.
Carcinogenesis
Estrogen receptor-?36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
Carcinogenesis
Exploiting the HSP60/10 chaperonin system as a chemotherapeutic target for colorectal cancer.
Carcinogenesis
Expression of 60-kD heat shock protein increases during carcinogenesis in the uterine exocervix.
Carcinogenesis
Expression of autophagy and ER stress-related proteins in primary salivary adenoid cystic carcinoma.
Carcinogenesis
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions.
Carcinogenesis
Expression of heat shock protein 60 kDa is upregulated in cervical cancer.
Carcinogenesis
Expression of heat shock protein70 in oral submucous fibrosis and oral squamous cell carcinoma: an immunohistochemical study.
Carcinogenesis
Expression of heat shock proteins in premalignant and malignant urothelial lesions of bovine urinary bladder.
Carcinogenesis
Expression of Hsp90 chaperome proteins in human tumor tissue.
Carcinogenesis
Expression of mortalin detected in human liver cancer by tissue microarrays.
Carcinogenesis
Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer.
Carcinogenesis
Functional role of Hsp60 as a positive regulator of human viral infection progression.
Carcinogenesis
Ganetespib and HSP90: Translating Preclinical Hypotheses into Clinical Promise.
Carcinogenesis
Geldanamycin administration reduces the amount of primordial germ cells in the mouse embryo.
Carcinogenesis
Geldanamycin and its anti-cancer activities.
Carcinogenesis
Geldanamycin-Induced PCNA Degradation in Isolated Hsp90 Complex from Cancer Cells.
Carcinogenesis
Gene expression pattern in canine mammary osteosarcoma.
Carcinogenesis
Gene Expression Signature-Based Approach Identifies Antifungal Drug Ciclopirox As a Novel Inhibitor of HMGA2 in Colorectal Cancer.
Carcinogenesis
Germ cell-specific heat shock protein 70-2 is expressed in cervical carcinoma and is involved in the growth, migration, and invasion of cervical cells.
Carcinogenesis
Glucose-regulated protein 78 (GRP78) as a potential novel biomarker and therapeutic target in multiple myeloma.
Carcinogenesis
Glucose-regulated protein 78 contributes to the proliferation and tumorigenesis of human colorectal carcinoma via AKT and ERK pathways.
Carcinogenesis
Gonadal apoptosis during sex reversal of the rice field eel: implications for an evolutionarily conserved role of the molecular chaperone heat shock protein 10.
Carcinogenesis
Grp78 as a therapeutic target for refractory head-neck cancer with CD24(-)CD44(+) stemness phenotype.
Carcinogenesis
GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice.
Carcinogenesis
GRP78 in lung cancer.
Carcinogenesis
GRP78 positively regulates estrogen?stimulated cell growth mediated by ER??36 in gastric cancer cells.
Carcinogenesis
HDAC6: Physiological function and its selective inhibitors for cancer treatment.
Carcinogenesis
Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma.
Carcinogenesis
Heat Shock Protein 27 Expression is Inversely Correlated with Atrophic Gastritis and Intraepithelial Neoplasia.
Carcinogenesis
Heat Shock Protein 90 Inhibition in Cancer Drug Discovery: From Chemistry to Futural Clinical Applications.
Carcinogenesis
Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia-lymphoma cells.
Carcinogenesis
Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation.
Carcinogenesis
Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.
Carcinogenesis
Heat Shock Protein 90 is Associated with Hyperplasia and Neoplastic Transformation of Canine Prostatic Epithelial Cells.
Carcinogenesis
Heat shock protein 90 is involved in the regulation of HMGA2-driven growth and epithelial-to-mesenchymal transition of colorectal cancer cells.
Carcinogenesis
Heat Shock Protein 90 Regulates Subcellular Localization of Smads in Mv1Lu Cells.
Carcinogenesis
Heat shock protein 90 stabilizes nucleolin to increase mRNA stability in mitosis.
Carcinogenesis
Heat shock protein expression in canine malignant mammary tumours.
Carcinogenesis
Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis.
Carcinogenesis
Heat shock protein90 in lobular neoplasia of the breast.
Carcinogenesis
Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?
Carcinogenesis
Heat shock proteins stimulate APOBEC-3-mediated cytidine deamination in the hepatitis B virus.
Carcinogenesis
Heat-shock protein 90 inhibitors in antineoplastic therapy: is it all wrapped up?
Carcinogenesis
Helicobacter pylori heat shock protein 60 antibodies are associated with gastric cancer.
Carcinogenesis
Helicobacter pylori-derived heat shock protein 60 increases the induction of regulatory T-cells associated with persistent infection.
Carcinogenesis
Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells.
Carcinogenesis
Highlights in experimental therapeutics.
Carcinogenesis
HMGN5 promotes IL-6-induced epithelial-mesenchymal transition of bladder cancer by interacting with Hsp27.
Carcinogenesis
Hsp27 and Hsp60 in human submandibular salivary gland: Quantitative patterns in healthy and cancerous tissues with potential implications for differential diagnosis and carcinogenesis.
Carcinogenesis
Hsp60 and Hsp10 down-regulation predicts bronchial epithelial carcinogenesis in smokers with chronic obstructive pulmonary disease.
Carcinogenesis
HSP60 as a drug target.
Carcinogenesis
HSP60 expression during carcinogenesis: a molecular "proteus" of carcinogenesis?
Carcinogenesis
HSP60 expression during carcinogenesis: where is the pilot?
Carcinogenesis
HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment.
Carcinogenesis
Hsp60: molecular anatomy and role in colorectal cancer diagnosis and treatment.
Carcinogenesis
HSP70 and ER expression in cervical intraepithelial neoplasia and cervical cancer.
Carcinogenesis
HSP90 and Co-chaperones: Impact on Tumor Progression and Prospects for Molecular-Targeted Cancer Therapy.
Carcinogenesis
Hsp90 in Cancer: Transcriptional Roles in the Nucleus.
Carcinogenesis
Hsp90 in the continuum of breast ductal carcinogenesis: Evaluation in precursors, preinvasive and ductal carcinoma lesions.
Carcinogenesis
HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells.
Carcinogenesis
Hsp90 inhibitor can inhibit UV carcinogenesis.
Carcinogenesis
Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents.
Carcinogenesis
Hsp90 Is Essential for Chl1-Mediated Chromosome Segregation and Sister Chromatid Cohesion.
Carcinogenesis
HSP90 Molecular Chaperones, Metabolic Rewiring, and Epigenetics: Impact on Tumor Progression and Perspective for Anticancer Therapy.
Carcinogenesis
Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60.
Carcinogenesis
Identification and Characterization of MortaparibPlus-A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms.
Carcinogenesis
Identification and functional characterization of nuclear mortalin in human carcinogenesis.
Carcinogenesis
Identification of the Differential Expression Profiles of Serum and Tissue Proteins During Rat Hepatocarcinogenesis.
Carcinogenesis
Identification of the role of mono-ADP-ribosylation in colorectal cancer by integrated transcriptome analysis.
Carcinogenesis
Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis.
Carcinogenesis
Immunohistochemical evaluation of expression of heat shock proteins HSP70 and HSP90 in mammary gland neoplasms in bitches.
Carcinogenesis
Immunohistochemical evaluation of PCNA, p53, HSP60, HSP10 and MUC-2 presence and expression in prostate carcinogenesis.
Carcinogenesis
Immunohistochemical tumour markers in endometrial carcinoma.
Carcinogenesis
Immunomorphological Pattern of Molecular Chaperones in Normal and Pathological Thyroid Tissues and Circulating Exosomes: Potential Use in Clinics.
Carcinogenesis
Improvement of inhibitor identification for heat shock protein 90? by utilizing a red-shifted fluorescence polarization probe.
Carcinogenesis
In silico design novel Vibsanin B derivatives as inhibitor for heat shock protein 90 based on 3D-QSAR, molecular docking and molecular dynamics simulation.
Carcinogenesis
In Vivo Suppression of Heat Shock Protein (HSP)27 and HSP70 Accelerates DMBA-Induced Skin Carcinogenesis by Inducing Antigenic Unresponsiveness to the Initiating Carcinogenic Chemical.
Carcinogenesis
Increased HSP27 correlates with malignant biological behavior of non-small cell lung cancer and predicts patient's survival.
Carcinogenesis
Induction of apoptosis by abrogation of HSP70 expression in human oral cancer cells.
Carcinogenesis
Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.
Carcinogenesis
Inhibition of the mitochondrial Hsp90 chaperone network: A novel, efficient treatment strategy for cancer?
Carcinogenesis
Innate immunity meets with cellular stress at the IKK complex: Regulation of the IKK complex by HSP70 and HSP90.
Carcinogenesis
Integration of microRNAome, proteomics and metabolomics to analyze arsenic-induced malignant cell transformation.
Carcinogenesis
Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients.
Carcinogenesis
Interactions between Hsp90 and oncogenic viruses: implications for viral cancer therapeutics.
Carcinogenesis
Investigation of anticancer activities of STA-9090 (ganetespib) as a second generation HSP90 inhibitor in Saos-2 osteosarcoma cells.
Carcinogenesis
In Vivo Conformational Dynamics of Hsp90 and Its Interactors.
Carcinogenesis
Is Mongolian gerbil really adequate host animal for study of Helicobacter pylori infection-induced gastritis and cancer?
Carcinogenesis
Landscape of the mitochondrial Hsp90 metabolome in tumours.
Carcinogenesis
Luteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3.
Carcinogenesis
Malignant transformation of NIH3T3 cells by overexpression of mot-2 protein.
Carcinogenesis
Maximizing the Therapeutic Potential of Hsp90 Inhibitors.
Carcinogenesis
Membrane HSP70: the molecule triggering gammadelta T cells in the early stage of tumorigenesis.
Carcinogenesis
Mimotope-hormesis and mortalin/grp75/mthsp70: a new hypothesis on how infectious disease-associated epitope mimicry may explain low cancer burden in developing nations.
Carcinogenesis
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.
Carcinogenesis
Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target.
Carcinogenesis
Molecular characterization of hsp90 isoforms in colorectal cancer cells and its association with tumour progression.
Carcinogenesis
Molecular genetics of the aip gene in familial pituitary tumorigenesis.
Carcinogenesis
Mortalin expression in pancreatic cancer and its clinical and prognostic significance.
Carcinogenesis
Mortalin maintains breast cancer stem cells stemness via activation of Wnt/GSK3?/?-catenin signaling pathway.
Carcinogenesis
Mortalin overexpression predicts poor prognosis in early stage of non-small cell lung cancer.
Carcinogenesis
Mortalin promotes cell proliferation and epithelial mesenchymal transition of intrahepatic cholangiocarcinoma cells in vitro.
Carcinogenesis
Mortalin - a multipotent chaperone regulating cellular processes ranging from viral infection to neurodegeneration.
Carcinogenesis
Multilevel regulation of RUVBL2 expression predicts poor prognosis in hepatocellular carcinoma.
Carcinogenesis
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity.
Carcinogenesis
MZF1 and SCAND1 Reciprocally Regulate CDC37 Gene Expression in Prostate Cancer.
Carcinogenesis
Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-?-catenin signaling in breast cancer.
Carcinogenesis
Nicotine increases oxidative stress, activates NF-kappaB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis.
Carcinogenesis
Novobiocin decreases SMYD3 expression and inhibits the migration of MDA-MB-231 human breast cancer cells.
Carcinogenesis
NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models.
Carcinogenesis
Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth.
Carcinogenesis
Oncogenic role of mortalin contributes to ovarian tumorigenesis by activating the MAPK-ERK pathway.
Carcinogenesis
Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma.
Carcinogenesis
Overexpression of 27-kDa heat shock protein relates to poor histological differentiation in human oesophageal squamous cell carcinoma.
Carcinogenesis
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
Carcinogenesis
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Carcinogenesis
Overexpression of PI3K-p110? in the progression of uterine cervical neoplasia and its correlation with pAkt and DJ-1.
Carcinogenesis
P4HB promotes HCC tumorigenesis through downregulation of GRP78 and subsequent upregulation of epithelial-to-mesenchymal transition.
Carcinogenesis
p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling.
Carcinogenesis
p53-HSP70 complexes in oral dysplasia and cancer: potential prognostic implications.
Carcinogenesis
Pifithrin-? induces necroptosis through oxidative mitochondrial damage but accompanies epithelial-mesenchymal transition-like phenomenon in malignant mesothelioma cells under lactic acidosis.
Carcinogenesis
Positive association of glucose-regulated protein 78 during oral cancer progression and the prognostic value in oral precancerous lesions.
Carcinogenesis
Posttranslational modification and beyond: interplay between histone deacetylase 6 and heat-shock protein 90.
Carcinogenesis
Potential Prognostic Value of Histone Deacetylase 6 and Acetylated Heat-Shock Protein 90 in Early-Stage Breast Cancer.
Carcinogenesis
Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP-BEP800.
Carcinogenesis
Prognostic significance of heat shock protein 70 expression in early gastric carcinoma.
Carcinogenesis
Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.
Carcinogenesis
Protective effect of Ocimum sanctum on 3-methylcholanthrene, 7,12-dimethylbenz(a)anthracene and aflatoxin B1 induced skin tumorigenesis in mice.
Carcinogenesis
Protective role of genetic polymorphism of heat shock protein 70-2 for gastric cancer risk.
Carcinogenesis
Proteomics-based identification of HSP60 as a tumor-associated antigen in early stage breast cancer and ductal carcinoma in situ.
Carcinogenesis
Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy.
Carcinogenesis
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Carcinogenesis
Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.
Carcinogenesis
Quantum dot-based protein imaging and functional significance of two mitochondrial chaperones in cellular senescence and carcinogenesis.
Carcinogenesis
Radiosensitization of human lung cancer cells by the novel purine-scaffold Hsp90 inhibitor, PU-H71.
Carcinogenesis
Recent Understanding and Future Directions of Recurrent Corticotroph Tumors.
Carcinogenesis
Reliability of HSP70 (HSPA) expression as a prognostic marker in glioma.
Carcinogenesis
Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I.
Carcinogenesis
Role of HSP60/HSP10 in Lung Cancer: Simple Biomarkers or Leading Actors?
Carcinogenesis
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer.
Carcinogenesis
Role of Krüppel-like factor 4 and heat shock protein 27 in cancer of the larynx.
Carcinogenesis
Roles of GRP78 in physiology and cancer.
Carcinogenesis
Serum GRP78 as a Tumor Marker and Its Prognostic Significance in Non-Small Cell Lung Cancers: A Retrospective Study.
Carcinogenesis
Silencing glucose-regulated protein 78 induced renal cell carcinoma cell line G1 cell-cycle arrest and resistance to conventional chemotherapy.
Carcinogenesis
Steady-State Levels of Phosphorylated Mitogen-Activated Protein Kinase Kinase 1/2 Determined by Mortalin/HSPA9 and Protein Phosphatase 1 Alpha in KRAS and BRAF Tumor Cells.
Carcinogenesis
Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis.
Carcinogenesis
Structural and functional differences between mouse mot-1 and mot-2 proteins that differ in two amino acids.
Carcinogenesis
Structural and functional specificity of small heat shock protein HspB1 and HspB4, two cellular partners of HspB5: Role of the in vitro hetero-complex formation in chaperone activity.
Carcinogenesis
Study of interactions energies between residues of the active site of Hsp90 and the geldanamycin analogues using Quantum Mechanics/Molecular Mechanics (QM/MM) methods.
Carcinogenesis
Super-telomeres in transformed human fibroblasts.
Carcinogenesis
Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis.
Carcinogenesis
Synuclein ? protects Akt and mTOR and renders tumor resistance to Hsp90 disruption.
Carcinogenesis
Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption.
Carcinogenesis
Targeting heat shock protein 90 for anti-cancer drug development.
Carcinogenesis
Targeting heat shock protein 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma.
Carcinogenesis
Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy.
Carcinogenesis
Targeting HSP90 for cancer therapy.
Carcinogenesis
Targeting multiple signal transduction pathways through inhibition of Hsp90.
Carcinogenesis
Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis.
Carcinogenesis
Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA.
Carcinogenesis
Ten kilodalton heat shock protein (HSP10) is overexpressed during carcinogenesis of large bowel and uterine exocervix.
Carcinogenesis
The antitumor agent PBT-1 directly targets HSP90 and hnRNP A2/B1 and inhibits lung adenocarcinoma growth and metastasis.
Carcinogenesis
The ATAD2/ANCCA homolog Yta7 cooperates with Scm3HJURP to deposit Cse4CENP-A at the centromere in yeast.
Carcinogenesis
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast.
Carcinogenesis
The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis.
Carcinogenesis
The critical role of GRP78 in physiologic and pathologic stress.
Carcinogenesis
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.
Carcinogenesis
The Interplay between Glucose-Regulated Protein 78 (GRP78) and Steroids in the Reproductive System.
Carcinogenesis
The Molecular Chaperone Hsp90 Is Required for Cell Cycle Exit in Drosophila melanogaster.
Carcinogenesis
The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme.
Carcinogenesis
The Role of Heat Shock Protein-90 in the Pathogenesis of Birt-Hogg-Dubé and Tuberous Sclerosis Complex Syndromes.
Carcinogenesis
The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.
Carcinogenesis
The small heat shock protein ?A-crystallin negatively regulates pancreatic tumorigenesis.
Carcinogenesis
TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas.
Carcinogenesis
trans, trans-2,4-Decadienal, a lipid peroxidation product, induces inflammatory responses via Hsp90- or 14-3-3?-dependent mechanisms.
Carcinogenesis
Transcript response of soft coral (Scleronephthya gracillimum) on exposure to polycyclic aromatic hydrocarbons.
Carcinogenesis
Transcriptional repression of the prosurvival endoplasmic reticulum chaperone GRP78/BIP by E2F1.
Carcinogenesis
TRAP1 regulates stemness through Wnt/?-catenin pathway in human colorectal carcinoma.
Carcinogenesis
Trianthema portulacastrum Linn. Displays Anti-Inflammatory Responses during Chemically Induced Rat Mammary Tumorigenesis through Simultaneous and Differential Regulation of NF-?B and Nrf2 Signaling Pathways.
Carcinogenesis
TRIB1 Supports Prostate Tumorigenesis and Tumor-Propagating Cell Survival by Regulation of Endoplasmic Reticulum Chaperone Expression.
Carcinogenesis
Tumor suppression by apoptotic and anti-angiogenic effects of mortalin-targeting adeno-oncolytic virus.
Carcinogenesis
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.
Carcinogenesis
Tumor-derived inducible heat-shock protein 70 (HSP70) is an essential component of anti-tumor immunity.
Carcinogenesis
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
Carcinogenesis
Understanding the Hsp90 N-terminal Dynamics: Structural and Molecular Insights into the Therapeutic Activities of Anticancer Inhibitors Radicicol (RD) and Radicicol Derivative (NVP-YUA922).
Carcinogenesis
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1.
Carcinogenesis
Unusual Suspects in the Twilight Zone Between the Hsp90 Interactome and Carcinogenesis.
Carcinogenesis
Up-Regulation of Cdc37 Contributes to Schwann Cell Proliferation and Migration After Sciatic Nerve Crush.
Carcinogenesis
Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.
Carcinogenesis
Viral insertion in Evi12 causes expression of aberrant Grp94 mRNAs containing the viral gag myristylation motif.
Carcinogenesis
Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors.
Carcinogenesis
[Cloning and analysis of geldanamycin partial biosynthetic gene cluster of Streptomyces hygroscopicus 17997]
Carcinogenesis
[Expressions of heat shock protein (HSP) family HSP 60, 70 and 90alpha in colorectal cancer tissues and their correlations to pathohistological characteristics.]
Carcinogenesis
[Molecular chaperone HSP90 as a novel target for cancer chemotherapy]
Carcinogenesis
[The correlation between the up-regulation of Hsp90 and drug resistance to cisplatin in lung cancer cell line].
Carcinogenesis
[The effect of antisense hsp90 beta on the malignant phenotype and sensitivity of HeLa cells to chemotherapeutic drugs]
Carcinoid Tumor
Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells.
Carcinoma
(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor.
Carcinoma
1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides.
Carcinoma
17-Allylamino-17-Demethoxygeldanamycin and MEK1/2 Inhibitors Kill GI Tumor Cells via Ca2+-Dependent Suppression of GRP78/BiP and Induction of Ceramide and Reactive Oxygen Species.
Carcinoma
18?-Glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.
Carcinoma
2-phenylethynesulfonamide inhibits growth of oral squamous cell carcinoma cells by blocking the function of heat shock protein 70.
Carcinoma
A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.
Carcinoma
A hsp70-2 mutation recognized by CTL on a human renal cell carcinoma.
Carcinoma
A microRNA-27a mimic sensitizes human oral squamous cell carcinoma HSC-4 cells to hyperthermia through downregulation of Hsp110 and Hsp90.
Carcinoma
A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma.
Carcinoma
A novel intronic circular RNA, circGNG7, inhibits head and neck squamous cell carcinoma progression by blocking the phosphorylation of heat shock protein 27 at Ser78 and Ser82.
Carcinoma
A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.
Carcinoma
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
Carcinoma
A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma.
Carcinoma
A role for HMGB1, HSP60 and Myd88 in growth of murine mammary carcinoma in vitro.
Carcinoma
A triazine compound S06 inhibits proinvasive crosstalk between carcinoma cells and stromal fibroblasts via binding to heat shock protein 90.
Carcinoma
A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration.
Carcinoma
Acquired resistance to HSP90 inhibitor 17-AAG and increased metastatic potential are associated with MUC1 expression in colon carcinoma cells.
Carcinoma
Adaptation of Ehrlich ascites carcinoma cells to energy deprivation in vivo can be associated with heat shock protein accumulation.
Carcinoma
Alpha B crystallin expression in response to hormone, oncogenes and stress.
Carcinoma
Alteration in gene expression profile by full-length hepatitis B virus genome.
Carcinoma
An immunohistochemical analysis of heat shock protein 70, p53, and estrogen receptor status in carcinoma of the uterine cervix.
Carcinoma
Analysis of polypeptide expression in benign and malignant human breast lesions.
Carcinoma
Analysis of polypeptide expression in benign and malignant human breast lesions: down-regulation of cytokeratins.
Carcinoma
Antibodies to heat-shock protein 27 are associated with improved survival in patients with breast cancer.
Carcinoma
Antitumor effect of novel HSP90 inhibitor NVP-AUY922 against oral squamous cell carcinoma.
Carcinoma
Antitumorigenic Effect of Hsp90 Inhibitor SNX-2112 on Tongue Squamous Cell Carcinoma is Enhanced by Low-Intensity Ultrasound.
Carcinoma
Association between hsp60 messenger-RNA levels and Cisplatin resistance in human head and neck-cancer cell-lines.
Carcinoma
Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.
Carcinoma
AuNPs modified, disposable, ITO based biosensor: Early diagnosis of heat shock protein 70.
Carcinoma
Benzylidene lactam compound, KNK437, a novel inhibitor of acquisition of thermotolerance and heat shock protein induction in human colon carcinoma cells.
Carcinoma
BIIB021, a novel Hsp90 inhibitor, sensitizes esophageal squamous cell carcinoma to radiation.
Carcinoma
BIIB021, a novel HSP90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy.
Carcinoma
CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.
Carcinoma
CD20+ Tumor Infiltrating B Lymphocyte in Oral Squamous Cell Carcinoma: Correlation with Clinicopathologic Characteristics and Heat Shock Protein 70 Expression.
Carcinoma
Cell surface expression of 70 kDa heat shock protein in human oral dysplasia and squamous cell carcinoma: correlation with clinicopathological features.
Carcinoma
Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung.
Carcinoma
Chaperonin (HSP60) and annexin-2 are candidate biomarkers for non-small cell lung carcinoma.
Carcinoma
Characterization of Exosomes in Plasma of Patients with Breast, Ovarian, Prostate, Hepatic, Gastric, Colon, and Pancreatic Cancers.
Carcinoma
Characterization of heat shock protein 27 phosphorylation sites in renal cell carcinoma.
Carcinoma
Characterization of proteins associated with heat shock protein hsp27 in the squamous cell carcinoma cell line A431.
Carcinoma
Clinical Implications of HSC70 Expression in Clear Cell Renal Cell Carcinoma.
Carcinoma
Clinical Significance of Monitoring Circulating Free DNA and Plasma Heat Shock Protein 90alpha in Patients with Esophageal Squamous Cell Carcinoma.
Carcinoma
Clinical significance of serum dynamics of HSP90a level in esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy.
Carcinoma
Clinicopathological and genetic characteristics of mucinous carcinomas in the colorectum.
Carcinoma
Co-expression of heat shock protein 70 and glucose-regulated protein 94 in human gastric carcinoma cell line BGC-823.
Carcinoma
Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis.
Carcinoma
Combination Treatment of Renal Cell Carcinoma with Belinostat and 5-Fluorouracil: A Role for Oxidative Stress Induced DNA Damage and HSP90 Regulated Thymidine Synthase.
Carcinoma
Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation.
Carcinoma
Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation.
Carcinoma
Complex Formation between Heat Shock Protein 72 and Hepatitis B Virus X Protein in Hepatocellular Carcinoma Tissues.
Carcinoma
Complex formation between heat shock protein 72 and hepatitis B virus X protein in hepatocellular carcinoma tissues.
Carcinoma
Concentrations of antibodies against heat shock protein 27 in the sera of women with ovarian carcinoma.
Carcinoma
Control of metastasized pancreatic carcinomas in SCID/beige mice with human IL-2/TKD-activated NK cells.
Carcinoma
Correlation between clinicopathology and expression of heat shock protein 70 and glucose-regulated protein 94 in human colonic adenocarcinoma.
Carcinoma
Correlation between clinicopathology and expression of heat shock protein 72 and glycoprotein 96 in human esophageal squamous cell carcinoma.
Carcinoma
Correlation between crystal violet dissolution assay and manual colony counting on the in vitro effects of Hsp90-inhibitors.
Carcinoma
Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan.
Carcinoma
Definition of extracellular localized epitopes of Hsp70 involved in an NK immune response.
Carcinoma
Diagnostic value of heat shock protein 90? and squamous cell carcinoma antigen in detection of cervical cancer.
Carcinoma
Diagnostic, clinicopathologic, therapeutic and prognostic value of Plasma Heat Shock Protein 90 levels in patients with advanced Gastrointestinal Carcinoma.
Carcinoma
Different expression of CD44, ICAM-1, and HSP60 on primary tumor and metastases of a human pancreatic carcinoma growing in scid mice.
Carcinoma
Differential expression of heat shock protein 27 in normal oral mucosa, oral epithelial dysplasia and squamous cell carcinoma.
Carcinoma
Differential Expression of Heat Shock Protein 27 in Oral Epithelial Dysplasias and Squamous Cell Carcinoma.
Carcinoma
Differential expression of hsp90, gelsolin and gst-pi in human gastric-carcinoma cell-lines.
Carcinoma
Differential expression of Mr 70,000 heat shock protein in normal, premalignant, and malignant human uterine cervix.
Carcinoma
Differentiation of normal and cancer cells induced by sulfhydryl reduction: biochemical and molecular mechanisms.
Carcinoma
Discovering High Potent Hsp90 Inhibitors as Antinasopharyngeal Carcinoma Agents through Fragment Assembling Approach.
Carcinoma
Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response.
Carcinoma
Double immunostaining for p53 and molecular chaperone hsp72/73 in gastric carcinoma.
Carcinoma
Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma.
Carcinoma
Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Carcinoma
Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells.
Carcinoma
Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
Carcinoma
Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma.
Carcinoma
Effect of 17-allylamino-17-demethoxygeldanamycin (17-AAG) on Akt protein expression is more effective in head and neck cancer cell lineages that retain PTEN protein expression.
Carcinoma
Effect of hypoxia on the expression of alphaB-crystallin in head and neck squamous cell carcinoma.
Carcinoma
Effect of social housing condition on heat shock protein (HSP) expression in the Shionogi mouse mammary carcinoma (SC115).
Carcinoma
Effects of 17-allylamino-17-demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT-116 cells.
Carcinoma
Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.
Carcinoma
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice.
Carcinoma
Effects of far infrared radiation by isotropic high-density carbon on the human oral mucosa.
Carcinoma
Effects of the novel heat shock protein 90 inhibitor AUY922 in renal cell carcinoma ACHN and 786-O cells.
Carcinoma
Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
Carcinoma
EIF3D promotes sunitinib resistance of renal cell carcinoma by interacting with GRP78 and inhibiting its degradation.
Carcinoma
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Carcinoma
Enhancing HSP70-ShRNA transfection in 22RV1 prostate cancer cells by combination of sonoporation, liposomes and HTERT/CMV chimeric promoter.
Carcinoma
Epstein-Barr virus upregulates phosphorylated heat shock protein 27 kDa in carcinoma cells using the phosphoinositide 3-kinase/Akt pathway.
Carcinoma
Estramustine phosphate enhances the effects of hyperthermia and induces the small heat shock protein HSP27 in the human prostate carcinoma cell line PC-3.
Carcinoma
Estrogen receptor-?36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
Carcinoma
Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator.
Carcinoma
Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110.
Carcinoma
Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung Cancer.
Carcinoma
Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma.
Carcinoma
Expression and localization of GRP75 in human epithelial tumors and normal tissues.
Carcinoma
Expression and significance of heat shock protein 70 and glucose-regulated protein 94 in human esophageal carcinoma.
Carcinoma
Expression of 60-kD heat shock protein increases during carcinogenesis in the uterine exocervix.
Carcinoma
Expression of autophagy and ER stress-related proteins in primary salivary adenoid cystic carcinoma.
Carcinoma
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions.
Carcinoma
Expression of ER stress markers (GRP78/BiP and PERK) in adenoid cystic carcinoma.
Carcinoma
Expression of Heat Shock Protein 105 in Cutaneous Squamous Cell Carcinoma: Correlation with Clinicopathological Characteristics.
Carcinoma
Expression of heat shock protein 27 in human renal cell carcinoma.
Carcinoma
Expression of heat shock protein 70 and c-myc in cervical carcinoma.
Carcinoma
Expression of heat shock protein 70 in grossly resected esophageal squamous cell carcinoma.
Carcinoma
Expression of Heat Shock Protein 70 in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: An Immunohistochemical Study.
Carcinoma
Expression of heat shock protein 70 in renal cell carcinoma and its relation to tumor progression and prognosis.
Carcinoma
Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients.
Carcinoma
Expression of heat shock protein70 in oral submucous fibrosis and oral squamous cell carcinoma: an immunohistochemical study.
Carcinoma
Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo.
Carcinoma
Expression of heat shock proteins HSP70 and HSP90 in endometrial carcinomas. Correlation with clinicopathology, sex steroid receptor status, and p53 protein expression.
Carcinoma
Expression of heat shock proteins in premalignant and malignant urothelial lesions of bovine urinary bladder.
Carcinoma
Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study.
Carcinoma
Expression of heat-shock protein Hsp60 correlated with the apoptotic index and patient prognosis in human oesophageal squamous cell carcinoma.
Carcinoma
Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries.
Carcinoma
Expression of HSP27, HSP72 and MRP proteins in in vitro co-culture of colon tumour cell spheroids with normal cells after incubation with rhTGF- beta1 and/or CPT-11.
Carcinoma
Expression of interleukin-6 is downregulated by 17-(allylamino)-17-demethoxygeldanamycin in human prostatic carcinoma cells.
Carcinoma
Expression of the 27-kDa heat shock protein (HSP27) in gastric carcinomas and adjacent normal, metaplastic, and dysplastic gastric mucosa, and its prognostic significance.
Carcinoma
Expression pattern of heat shock protein 90 in patients with oral squamous cell carcinoma in northern Taiwan.
Carcinoma
Expression patterns of aurora kinase B, heat shock protein 47, and periostin in esophageal squamous cell carcinoma.
Carcinoma
Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cells.
Carcinoma
Extracellular heat shock protein A9 is a novel interaction partner of podoplanin in oral squamous cell carcinoma cells.
Carcinoma
Flow cytometric analysis of the heat shock protein 60 expressed on the cell surface of Helicobacter pylori.
Carcinoma
Fluoxetine-induced regulation of heat shock protein 90 and 14-3-3? in human embryonic carcinoma cells.
Carcinoma
Geldanamycin mediates the apoptosis of gastric carcinoma cells through inhibition of EphA2 protein expression.
Carcinoma
Geldanamycin, an inhibitor of Hsp90, sensitizes human tumour cells to radiation.
Carcinoma
Germ cell-specific heat shock protein 70-2 is expressed in cervical carcinoma and is involved in the growth, migration, and invasion of cervical cells.
Carcinoma
Glucose-deprived HT-29 human colon carcinoma cells are sensitive to verrucosidin as a GRP78 down-regulator.
Carcinoma
Glucose-regulated protein 78 expression in urothelial carcinoma of the upper urinary tract.
Carcinoma
Glucose-related protein (GRP78) and its relationship to the drug-resistance proteins P170, GST-pi, LRP56 and angiogenesis in non-small cell lung carcinomas.
Carcinoma
GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma.
Carcinoma
Heat shock protein (HSP72) surface expression enhances the lysis of a human renal cell carcinoma by IL-2 stimulated NK cells.
Carcinoma
Heat shock protein 105 is overexpressed in squamous cell carcinoma and extramammary Paget disease but not in basal cell carcinoma.
Carcinoma
Heat shock protein 27 and p16 immunohistochemistry in cervical intraepithelial neoplasia and squamous cell carcinoma.
Carcinoma
Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma.
Carcinoma
Heat shock protein 27 enhances the tumorigenicity of immunogenic rat colon carcinoma cell clones.
Carcinoma
Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
Carcinoma
Heat shock protein 27: an independent prognostic indicator of survival in patients with epithelial ovarian carcinoma.
Carcinoma
Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells.
Carcinoma
Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery.
Carcinoma
Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer.
Carcinoma
Heat shock protein 70 and tumor-infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).
Carcinoma
Heat shock protein 70 expression in relation to apoptosis in primary bladder transitional cell carcinoma.
Carcinoma
Heat shock protein 70 is acute phase reactant: response elicited by tumor treatment with photodynamic therapy.
Carcinoma
Heat shock protein 70 is involved in malignant behaviors and chemosensitivities to cisplatin in cervical squamous cell carcinoma cells.
Carcinoma
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells.
Carcinoma
Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth.
Carcinoma
Heat shock protein 72 associated with CD44v6 in human colonic adenocarcinoma.
Carcinoma
Heat shock protein 72 does not modulate ionizing radiation-induced apoptosis in U1810 non-small cell lung carcinoma cells.
Carcinoma
Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation.
Carcinoma
Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis.
Carcinoma
Heat shock protein 90 is a putative therapeutic target in patients with recurrent advanced-stage ovarian carcinoma with serous effusions.
Carcinoma
Heat Shock Protein 90 is Associated with Hyperplasia and Neoplastic Transformation of Canine Prostatic Epithelial Cells.
Carcinoma
Heat shock protein and p53 expression in head and neck squamous cell carcinoma.
Carcinoma
Heat shock protein expression and anti-heat shock protein reactivity in renal cell carcinoma.
Carcinoma
Heat shock protein expression in canine malignant mammary tumours.
Carcinoma
Heat shock protein expression in oral epithelial dysplasia and squamous cell carcinoma.
Carcinoma
Heat shock protein family B member 1 facilitates ezrin activation to control cell migration in esophageal squamous cell carcinoma.
Carcinoma
Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups.
Carcinoma
Heat shock proteins HSP27, HSP60, HSP70, and HSP90: expression in bladder carcinoma.
Carcinoma
Heat Shock Proteins: A Potential Anticancer Target.
Carcinoma
Heat-shock protein 70 as a tumor antigen for in vitro dendritic cell pulsing in renal cell carcinoma cases.
Carcinoma
Heat-shock protein 70-2 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumour progression and promotes migration and invasion.
Carcinoma
Heat-shock protein 90 (Hsp90) as a molecular target for therapy of gastrointestinal cancer.
Carcinoma
Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.
Carcinoma
High Expression of GRP78 Promotes Invasion and Metastases in Patients with Esophageal Squamous Cell Carcinoma.
Carcinoma
High expression of heat shock protein 90 is associated with tumor aggressiveness and poor prognosis in patients with advanced gastric cancer.
Carcinoma
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
Carcinoma
High-throughput screening fluorescence polarization assay for tumor-specific hsp90.
Carcinoma
HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.
Carcinoma
Hsp-27 has no diagnostic or prognostic significance in prostate or bladder cancers.
Carcinoma
HSP105 expression in oral squamous cell carcinoma: Correlation with clinicopathological features and outcomes.
Carcinoma
Hsp27 modulates p53 signaling and suppresses cellular senescence.
Carcinoma
HSP60 and HSP10 as diagnostic and prognostic tools in the management of exocervical carcinoma.
Carcinoma
HSP60 silencing promotes Warburg-like phenotypes and switches the mitochondrial function from ATP production to biosynthesis in ccRCC cells.
Carcinoma
HSP70: a promising target for laryngeal carcinoma radiaotherapy by inhibiting cleavage and degradation of nucleolin.
Carcinoma
Hsp90 as a therapeutic target in patients with oesophageal carcinoma.
Carcinoma
Hsp90 inhibition by NVP-AUY922 and NVP-BEP800 decreases migration and invasion of irradiated normoxic and hypoxic tumor cell lines.
Carcinoma
Hsp90 inhibitor can inhibit UV carcinogenesis.
Carcinoma
HSP90 Inhibitor Ganetespib (STA-9090) Inhibits Tumor Growth in c-Myc-Dependent Esophageal Squamous Cell Carcinoma.
Carcinoma
HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.
Carcinoma
Hsp90 inhibitors cause G2/M arrest associated with the reduction of Cdc25C and Cdc2 in lung cancer cell lines.
Carcinoma
Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.
Carcinoma
Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells.
Carcinoma
Identification of candidate antigens for serologic detection of Helicobacter pylori-infected patients with gastric carcinoma.
Carcinoma
Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library.
Carcinoma
Identification of tumor-associated proteins in oral tongue squamous cell carcinoma by proteomics.
Carcinoma
IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.
Carcinoma
Immunohistochemical analysis of p53 protein and 72 kDa heat shock protein (HSP72) expression in ovarian carcinomas. Correlation with clinicopathology and sex steroid receptor status.
Carcinoma
Immunohistochemical detection of HSP60-expression in human ovarian cancer. Correlation with survival in a series of 247 patients.
Carcinoma
Immunohistochemical expression of heat shock proteins, p63 and androgen receptor in benign prostatic hyperplasia and prostatic carcinoma in the dog.
Carcinoma
Immunohistochemical expression of interlukin10 (IL10) and heat shock protein-90 (HSP-90) in prostatic carcinoma.
Carcinoma
Immunotherapy of a human papillomavirus (HPV) type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guérin (BCG) hsp65 and HPV16 E7.
Carcinoma
Increase of P-glycoprotein-mediated drug resistance by hsp 90 beta.
Carcinoma
Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma.
Carcinoma
Increased expression of HSP70 by colon cancer cells is not always associated with access to the dendritic cell cross-presentation pathway.
Carcinoma
Increased expression of the major heat shock protein Hsp72 in human prostate carcinoma cells is dispensable for their viability but confers resistance to a variety of anticancer agents.
Carcinoma
Induction and epitope analysis of Helicobacter pylori heat shock protein.
Carcinoma
Induction and membrane expression of heat shock proteins in heat-treated HPC-4 cells is correlated with increased resistance to LAK-mediated lysis.
Carcinoma
Induction of heat shock protein 70 inhibits NF-kappa-B in squamous cell carcinoma.
Carcinoma
Induction of the 72-kD heat shock protein in human skin melanoma and squamous cell carcinoma cell lines.
Carcinoma
Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2? pathway.
Carcinoma
Inhibition of GRP78 abrogates radioresistance in oropharyngeal carcinoma cells after EGFR inhibition by cetuximab.
Carcinoma
Inhibition of heat shock protein expression by Helicobacter pylori.
Carcinoma
Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone.
Carcinoma
Interaction between heat shock protein 72 and alpha-fetoprotein in human hepatocellular carcinomas.
Carcinoma
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
Carcinoma
Involvement of GRP78 in the Resistance of Ovarian Carcinoma Cells to Paclitaxel.
Carcinoma
Is p53 and heat shock protein 70 expression a useful parameter for preoperative hyperthermoradiation therapy in advanced rectal carcinoma.
Carcinoma
Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors.
Carcinoma
Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia.
Carcinoma
Kynuramines induce overexpression of heat shock proteins in pancreatic cancer cells via 5-hydroxytryptamine and MT1/MT2 receptors.
Carcinoma
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer.
Carcinoma
Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells.
Carcinoma
Luteolin induces carcinoma cell apoptosis through binding Hsp90 to suppress constitutive activation of STAT3.
Carcinoma
MEK-inhibitor PD184352 enhances the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922: the role of cell type and drug-irradiation schedule.
Carcinoma
Membrane Hsp70-supported cell-to-cell connections via tunneling nanotubes revealed by live-cell STED nanoscopy.
Carcinoma
Metastasis and the Tumor Microenvironment: A Joint Metastasis Research Society-AACR Conference - Research on Metastasis: Part 2.
Carcinoma
MicroRNA-27a downregulates the expression of Hsp90 and enhances the radiosensitivity in esophageal squamous cell carcinoma.
Carcinoma
MicroRNA-30a-5p Inhibits the Growth of Renal Cell Carcinoma by Modulating GRP78 Expression.
Carcinoma
Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX.
Carcinoma
Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.
Carcinoma
Mortalin is a distinct bio-marker and prognostic factor in serous ovarian carcinoma.
Carcinoma
Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.
Carcinoma
mRNA levels of molecular chaperones hsp27, hsp60 and hsp70 in cisplatin resistant squamous cell carcinomas.
Carcinoma
Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors.
Carcinoma
Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells.
Carcinoma
Novel Heat Shock Protein 90 Inhibitors Suppress P-Glycoprotein Activity and Overcome Multidrug Resistance in Cancer Cells.
Carcinoma
Novel HSP90 Inhibitor NVP-AUY922 enhances the anti-tumor effect of temsirolimus against oral squamous cell carcinoma.
Carcinoma
Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53.
Carcinoma
Nucleofection of non-B cells with mini-Epstein-Barr virus DNA.
Carcinoma
Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma.
Carcinoma
Overexpression of 27-kDa heat shock protein relates to poor histological differentiation in human oesophageal squamous cell carcinoma.
Carcinoma
Overexpression of endoplasmic reticulum stress-related proteins, XBP1s and GRP78, predicts poor prognosis in pulmonary adenocarcinoma.
Carcinoma
Overexpression of glucose-regulated protein 78 in colon cancer.
Carcinoma
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
Carcinoma
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Carcinoma
Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors.
Carcinoma
Overexpression of heat shock protein 27 (HSP-27) is associated with bad prognosis in oral squamous cell carcinoma.
Carcinoma
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix.
Carcinoma
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.
Carcinoma
Overexpression of heat shock protein 27 is associated with good prognosis in the patient with oral squamous cell carcinoma.
Carcinoma
Overexpression of the small heat shock protein, hsp27, confers resistance to hyperthermia, but not to oxidative stress and UV-induced cell death, in a stably transfected squamous cell carcinoma cell line.
Carcinoma
p53 mutations, ras mutations, and p53-heat shock 70 protein complexes in human lung carcinoma cell lines.
Carcinoma
P53-dependent radiosensitizing effects of Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin on human oral squamous cell carcinoma cell lines.
Carcinoma
Papers to Appear in Forthcoming Issues
Carcinoma
Peripheral blood mononuclear cell proliferation to heat shock protein-70 derived from autologous lung carcinoma.
Carcinoma
Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis.
Carcinoma
Polymorphic analysis of MHClinked Heat Shock Protein 70 genes: Their susceptibility and prognostic implication in Kangri cancer cases of Kashmiri population.
Carcinoma
Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo.
Carcinoma
Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKT.
Carcinoma
Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model.
Carcinoma
Pro-apoptotic effect of haem oxygenase-1 in human colorectal carcinoma cells via endoplasmic reticular stress.
Carcinoma
Prognostic significance of heat shock protein 27 (HSP27) in patients with oral squamous cell carcinoma.
Carcinoma
Prognostic significance of heat shock protein 70 expression in early gastric carcinoma.
Carcinoma
Prognostic significance of heat shock proteins HSP70 and HSP90 in endometrial carcinomas.
Carcinoma
Proliferating cell nuclear antigen and heat shock protein 70 immunolocalization in invasive ductal breast cancer not otherwise specified.
Carcinoma
Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma.
Carcinoma
Protein Expression Profile using Two-Dimensional Gel Analysis in Squamous Cervical Cancer Patients.
Carcinoma
Protein expression profiling of normal and neoplastic canine prostate and bladder tissue.
Carcinoma
Proteomic analysis of proteome and histone post-translational modifications in heat shock protein 90 inhibition-mediated bladder cancer therapeutics.
Carcinoma
Proteomic approaches to study epigallocatechin gallate-provoked apoptosis of TSGH-8301 human urinary bladder carcinoma cells: Roles of AKT and heat shock protein 27-modulated intrinsic apoptotic pathways.
Carcinoma
Proteomics-based identification of autoantibody against heat shock protein 70 as a diagnostic marker in esophageal squamous cell carcinoma.
Carcinoma
Quality of life in patients with metastatic renal cell carcinoma participating in a phase I trial of an autologous tumor-derived vaccine.
Carcinoma
Quantitative score modulation of HSP90 and HSP27 in clear cell renal cell carcinoma.
Carcinoma
Quercetin, an inhibitor of heat shock protein synthesis, inhibits the acquisition of thermotolerance in a human colon carcinoma cell line.
Carcinoma
Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
Carcinoma
Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins.
Carcinoma
Radiosensitization of human lung cancer cells by the novel purine-scaffold Hsp90 inhibitor, PU-H71.
Carcinoma
Regulation of HSP60 mRNA expression in a human ovarian carcinoma cell line.
Carcinoma
Relationship between expression of HSP60, urease activity, production of vacuolating toxin, and adherence activity of Helicobacter pylori.
Carcinoma
Relationship between heat shock protein 60 (HSP60) mRNA expression and resistance to platinum analogues in human ovarian and bladder carcinoma cell lines.
Carcinoma
Relationship between toxicity of selected insecticides and expression of stress proteins (HSP, GRP) in cultured human cells: Effects of commercial formulations versus pure active molecules.
Carcinoma
Retraction: Potentiation of Paclitaxel Activity by the HSP90 Inhibitor 17-allylamino-17-demethoxygeldanamycin in Human Ovarian Carcinoma Cell Lines with High Levels of Activated AKT.
Carcinoma
RT-PCR Quantitation of HSP60 mRNA Expression.
Carcinoma
Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.
Carcinoma
Selective cytotoxic activity of valinomycin against HT-29 Human colon carcinoma cells via down-regulation of GRP78.
Carcinoma
Serum antibody response to the heat shock protein 60 of Chlamydia trachomatis in women with developing cervical cancer.
Carcinoma
Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma.
Carcinoma
Significance of expression of heat shock protein90alpha in human gastric cancer.
Carcinoma
Significance of heat shock protein-27 expression in patients with renal cell carcinoma.
Carcinoma
Silence of HDAC6 suppressed esophageal squamous cell carcinoma proliferation and migration by disrupting chaperone function of HSP90.
Carcinoma
Silencing of heat shock protein 27 increases the radiosensitivity of non?small cell lung carcinoma cells.
Carcinoma
Single-Cell RNA Sequencing Identifies Yes-Associated Protein 1-Dependent Hepatic Mesothelial Progenitors in Fibrolamellar Carcinoma.
Carcinoma
Single-Cell Sequencing to Identify Six Heat Shock Protein (HSP) Genes-Mediated Progression Subtypes of Clear Cell Renal Cell Carcinoma.
Carcinoma
Small heat shock protein hsp27 as a possible mediator of intercellular adhesion-induced drug resistance in human larynx carcinoma HEp-2 cells.
Carcinoma
Sulfoxythiocarbamate S-4 inhibits HSP90 in human cutaneous squamous cell carcinoma cells.
Carcinoma
SUMOylation of HSP27 regulates PKM2 to promote esophageal squamous cell carcinoma progression.
Carcinoma
Suppression of the transformed phenotype and induction of differentiation-like characteristics in cultured ovarian tumor cells by chronic treatment with progesterone.
Carcinoma
Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells.
Carcinoma
Suppressive subtractive hybridisation reveals differential expression of serglycin, sorcin, bone marrow proteoglycan and prostate-tumour-inducing gene I (PTI-1) in drug-resistant and sensitive tumour cell lines of haematopoetic origin.
Carcinoma
Surface expression of a C-terminal alpha-helix region in heat shock protein 72 on murine LL/2 lung carcinoma can be recognized by innate immune sentinels.
Carcinoma
Synergistic effect of heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin and X-rays, but not carbon-ion beams, on lethality in human oral squamous cell carcinoma cells.
Carcinoma
Targeted blockade of HSP90 impairs DNA-damage response proteins and increases the sensitivity of ovarian carcinoma cells to PARP inhibition.
Carcinoma
Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors.
Carcinoma
Targeting Hsp90 in urothelial carcinoma.
Carcinoma
The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit.
Carcinoma
The effects of irradiation on the expression of a tumour rejection antigen (heat shock protein gp96) in human cervical cancer.
Carcinoma
The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase.
Carcinoma
The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization.
Carcinoma
The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells.
Carcinoma
The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
Carcinoma
The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells.
Carcinoma
The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons.
Carcinoma
The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas.
Carcinoma
Therapeutic effects of radiolabeled 17-allylamino-17-demethoxygeldanamycin on human H460 nonsmall-cell lung carcinoma xenografts in mice.
Carcinoma
Therapeutic uses of HSP90 inhibitors in Non-Small Cell Lung Carcinoma (NSCLC).
Carcinoma
Topically Applied Hsp90 Inhibitor 17AAG Inhibits UVR-Induced Cutaneous Squamous Cell Carcinomas.
Carcinoma
TRAP1 controls cell cycle G2-M transition through the regulation of CDK1 and MAD2 expression/ubiquitination.
Carcinoma
Tricyclic series of heat shock protein 90 (Hsp90) inhibitors part I: discovery of tricyclic imidazo[4,5-c]pyridines as potent inhibitors of the Hsp90 molecular chaperone.
Carcinoma
Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer.
Carcinoma
Tumor Suppression Efficacy of Heat Shock Protein 90 Inhibitor 17AAG in a Liposarcoma Mouse Model.
Carcinoma
Two-dimensional gel analysis of protein expression profile in squamous cervical cancer patients.
Carcinoma
Upregulation of GRP78 in Renal Cell Carcinoma and Its Significance.
Carcinoma
Use of protein-based biomarkers of exfoliated cervical cells for primary screening of cervical cancer.
Carcinoma
[Adenovirus-mediated antisense HSP70 cDNA transfection inhibits the growth of laryngeal carcinoma Hep-2 cells]
Carcinoma
[Anticancer therapeutic effect of SEA-linked and membrane-bound HSP70-expressed intestine-carcinoma vaccine]
Carcinoma
[Antitumor therapeutic effect induced by intestine- carcinoma cells vaccine expressing membrane-bound heat shock protein 70]
Carcinoma
[Biology behavior of head and neck squamous cell cancer cells changes after knocking down heat shock protein 27].
Carcinoma
[Comparative study of expression levels of the major human heat shock proteins in cancer and normal tissues]
Carcinoma
[Diagnosis value of combined detection of serum golgi protein 73, desgamma carboxy prothrombin and ?-fetoprotein in primary hepatic carcinoma].
Carcinoma
[Effect of glucose regulated protein 78 on autophagy and apoptosis in ovarian epithelial carcinoma].
Carcinoma
[Expression and significance of heat shock proteins in esophageal squamous cell carcinoma]
Carcinoma
[Expression and significance of Hsp70 and PCNA during the development of forestomach carcinoma in NIH mice]
Carcinoma
[Expression of heat shock protein-70, estrogen receptor and progesterone receptor in ovarian carcinomas and the correlation between HSP70 and sex steroid receptor]
Carcinoma
[Expression of heat shock proteins in laryngeal carcinoma]
Carcinoma
[Expression of Hsp70 Grp94 and IgG in human lung carcinoma.]
Carcinoma
[Hypoxia induces heat shock protein HSP70-2 expression in a HIF-1 dependent manner.]
Carcinoma
[Influence of the expression of heat shock protein 70 in maxillofacial squamous cell carcinoma by thermochemotherapy]
Carcinoma
[Isolation, identification and clinical significance of ascites-derived exosomes from patients with ovarian epithelial cancer]
Carcinoma
[Pancreatic acinar neoplasms : Comparative molecular characterization].
Carcinoma
[Preliminary study on glucose regulated protein 78 kD and heat shock protein 20 differential expression between left-sided colon carcinoma and right-sided colon carcinoma].
Carcinoma
[Screening of differentially expressed proteins from human esophageal cancer and esophageal tissues by two-dimensional difference gel electrophoresis and mass spectrometry]
Carcinoma
[Study on expression of cell cycle-related genes in subclonal cell lines of human cervical carcinoma]
Carcinoma
[The role of the heat shock protein in human breast cancer]
Carcinoma in Situ
Heat shock proteins HSP27, HSP60, HSP70, and HSP90: expression in bladder carcinoma.
Carcinoma in Situ
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.
Carcinoma, Acinar Cell
[Pancreatic acinar neoplasms : Comparative molecular characterization].
Carcinoma, Adenoid Cystic
Expression of autophagy and ER stress-related proteins in primary salivary adenoid cystic carcinoma.
Carcinoma, Adenoid Cystic
Expression of ER stress markers (GRP78/BiP and PERK) in adenoid cystic carcinoma.
Carcinoma, Adenosquamous
Hsp60 and Hsp10 down-regulation predicts bronchial epithelial carcinogenesis in smokers with chronic obstructive pulmonary disease.
Carcinoma, Basal Cell
Heat shock protein 105 is overexpressed in squamous cell carcinoma and extramammary Paget disease but not in basal cell carcinoma.
Carcinoma, Basal Cell
Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups.
Carcinoma, Ductal
Comparison of the desmoplastic reaction and invading ability in invasive ductal carcinoma of the breast and prostatic adenocarcinoma based on the expression of heat shock protein 47 and fascin.
Carcinoma, Ductal
Decreased Hsp90 expression in infiltrative lobular carcinoma: an immunohistochemical study.
Carcinoma, Ductal
Elevated expression of nuclear Hsp90 in invasive breast tumors.
Carcinoma, Ductal
Heat shock protein 27 overexpression in breast cancer lymph node metastasis.
Carcinoma, Ductal
Heat shock protein 90 (hsp90) expression and breast cancer.
Carcinoma, Ductal
Hsp-27 has no diagnostic or prognostic significance in prostate or bladder cancers.
Carcinoma, Ductal
Hsp90 in the continuum of breast ductal carcinogenesis: Evaluation in precursors, preinvasive and ductal carcinoma lesions.
Carcinoma, Ductal
Metastasis and the Tumor Microenvironment: A Joint Metastasis Research Society-AACR Conference - Research on Metastasis: Part 2.
Carcinoma, Ductal
Proteomics-based identification of HSP60 as a tumor-associated antigen in early stage breast cancer and ductal carcinoma in situ.
Carcinoma, Ductal
Serum levels of HSP90 in the continuum of breast ductal and lobular lesions.
Carcinoma, Ductal
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast.
Carcinoma, Ehrlich Tumor
Cisplatin induces the small heat shock protein hsp25 and thermotolerance in Ehrlich ascites tumor cells.
Carcinoma, Ehrlich Tumor
Dephosphorylation of the small heat shock protein hsp25 by calcium/calmodulin-dependent (type 2B) protein phosphatase.
Carcinoma, Ehrlich Tumor
Identification of the phosphorylation sites of the murine small heat shock protein hsp25.
Carcinoma, Ehrlich Tumor
The anti-cancer drug cisplatin induces H25 in Ehrlich ascites tumor cells by a mechanism different from transcriptional stimulation influencing predominantly H25 translation.
Carcinoma, Embryonal
A Chemical Biology Study of Human Pluripotent Stem Cells Unveils HSPA8 as a Key Regulator of Pluripotency.
Carcinoma, Embryonal
Cell-lineage-specific expression of the mouse hsp68 gene during embryogenesis.
Carcinoma, Embryonal
Cellular HSP90 (HSP86) mRNA level and in vitro differentiation of mouse embryonal carcinoma (F9) cells.
Carcinoma, Embryonal
Expression of the glucose-regulated proteins (GRP94 and GRP78) in differentiated and undifferentiated mouse embryonic cells and the use of the GRP78 promoter as an expression system in embryonic cells.
Carcinoma, Embryonal
Function of 90-kDa heat shock protein in cellular differentiation of human embryonal carcinoma cells.
Carcinoma, Embryonal
Heat shock protein synthesis in preimplantation mouse embryos and embryonal carcinoma cells.
Carcinoma, Embryonal
Regulation of J6 gene expression by transcription factor GATA-4.
Carcinoma, Embryonal
The small heat shock protein hsp25 is accumulated in P19 embryonal carcinoma cells and embryonic stem cells of line BLC6 during differentiation.
Carcinoma, Embryonal
Unusual levels of heat shock element-binding activity in embryonal carcinoma cells.
Carcinoma, Endometrioid
GRP78 Mediates Cell Growth and Invasiveness in Endometrial Cancer.
Carcinoma, Hepatocellular
1,3,5-Trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone directly targets heat shock protein 27 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
14-3-3? induces heat shock protein 70 expression in hepatocellular carcinoma.
Carcinoma, Hepatocellular
15-Lipoxygenase-1/15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells growth through protein kinase B and heat shock protein 90 complex activation.
Carcinoma, Hepatocellular
17-Demethoxy-reblastatin, an Hsp90 inhibitor, induces mitochondria-mediated apoptosis through downregulation of Mcl-1 in human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor.
Carcinoma, Hepatocellular
A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene.
Carcinoma, Hepatocellular
A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Carcinoma, Hepatocellular
A Targetable Molecular Chaperone Hsp27 Confers Aggressiveness in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathways.
Carcinoma, Hepatocellular
Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells.
Carcinoma, Hepatocellular
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis.
Carcinoma, Hepatocellular
ADP-ribosylation of the molecular chaperone GRP78/BiP.
Carcinoma, Hepatocellular
Analysis of hsp70 mRNA levels in HepG2 cells exposed to various metals differing in toxicity.
Carcinoma, Hepatocellular
Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70.
Carcinoma, Hepatocellular
Application of Immunohistochemistry in the Pathological Diagnosis of Liver Tumors.
Carcinoma, Hepatocellular
Attenuated phosphorylation of heat shock protein 27 correlates with tumor progression in patients with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Brefeldin A as a regulator of grp78 gene expression in mammalian cells.
Carcinoma, Hepatocellular
C0818, a novel curcumin derivative, induces ROS-dependent cytotoxicity in human hepatocellular carcinoma cells in vitro via disruption of Hsp90 function.
Carcinoma, Hepatocellular
Cell cycle regulation of the chicken hsp90 alpha expression.
Carcinoma, Hepatocellular
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Carcinoma, Hepatocellular
Chaperone action in the posttranslational topological reorientation of the hepatitis B virus large envelope protein: Implications for translocational regulation.
Carcinoma, Hepatocellular
CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy.
Carcinoma, Hepatocellular
Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78.
Carcinoma, Hepatocellular
Co-localization of the heat shock protein and human immunoglobulin G in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Combination of HSP90 and autophagy inhibitors promotes hepatocellular carcinoma apoptosis following incomplete thermal ablation.
Carcinoma, Hepatocellular
Combined use of heat-shock protein 70 and glutamine synthetase is useful in the distinction of typical hepatocellular adenoma from atypical hepatocellular neoplasms and well-differentiated hepatocellular carcinoma.
Carcinoma, Hepatocellular
Comparative proteomics of rat liver and Morris hepatoma 7777 plasma membranes.
Carcinoma, Hepatocellular
Complex Formation between Heat Shock Protein 72 and Hepatitis B Virus X Protein in Hepatocellular Carcinoma Tissues.
Carcinoma, Hepatocellular
Complex formation between heat shock protein 72 and hepatitis B virus X protein in hepatocellular carcinoma tissues.
Carcinoma, Hepatocellular
Concomitant overexpression of heat-shock protein 70 and HLA class-I in hepatitis C virus-related hepatocellular carcinoma.
Carcinoma, Hepatocellular
Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity.
Carcinoma, Hepatocellular
Conformational Landscape of the PRKACA-DNAJB1 Chimeric Kinase, the Driver for Fibrolamellar Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Correction to: Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial.
Carcinoma, Hepatocellular
Curcumin Upregulates Antioxidant Defense, Lon Protease, and Heat-Shock Protein 70 Under Hyperglycemic Conditions in Human Hepatoma Cells.
Carcinoma, Hepatocellular
Cytoplasmic sequestration of the tumor suppressor p53 by a heat shock protein 70 family member, mortalin, in human colorectal adenocarcinoma cell lines.
Carcinoma, Hepatocellular
Dendritic cells pulsed with Hsp70 and HBxAg induce specific antitumor immune responses in hepatitis B virus?associated hepatocellular carcinoma.
Carcinoma, Hepatocellular
Dendritic cells transfected with heat-shock protein 70 messenger RNA for patients with hepatitis C virus-related hepatocellular carcinoma: a phase 1 dose escalation clinical trial.
Carcinoma, Hepatocellular
Destabilization of PDK1 by Hsp90 inactivation suppresses hepatitis C virus replication through inhibition of PRK2-mediated viral RNA polymerase phosphorylation.
Carcinoma, Hepatocellular
Development of human hepatocellular carcinoma cell-targeted protein cages.
Carcinoma, Hepatocellular
Diagnostic Value of Glypican3, Heat Shock Protein 70 and Glutamine Synthetase in Hepatocellular Carcinoma Arising in Cirrhotic and Non-Cirrhotic Livers.
Carcinoma, Hepatocellular
Differential proteomics identification of HSP90 as potential serum biomarker in hepatocellular carcinoma by two-dimensional electrophoresis and mass spectrometry.
Carcinoma, Hepatocellular
Dinitrosyl iron complexes with thiol-containing ligands and S-nitroso-D,L-penicillamine as inductors of heat shock protein synthesis in H35 hepatoma cells.
Carcinoma, Hepatocellular
Direct association of heat shock protein 20 (HSPB6) with phosphoinositide 3-kinase (PI3K) in human hepatocellular carcinoma: regulation of the PI3K activity.
Carcinoma, Hepatocellular
Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells.
Carcinoma, Hepatocellular
Dynamic expression of rat heat shock protein gp96 and its gene during development of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Effect of 5-aza-2'-deoxycytidine on immune-associated proteins in exosomes from hepatoma.
Carcinoma, Hepatocellular
Effects of heat stress on the level of heat shock protein 70 on the surface of hepatocellular carcinoma Hep G2 cells: implications for the treatment of tumors.
Carcinoma, Hepatocellular
Effects of HSP70 antisense oligonucleotide on the proliferation and apoptosis of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Effects of the epigenetic drug MS-275 on the release and function of exosome-related immune molecules in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Elevated Mortalin correlates with poor outcome in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Enhanced antitumor effects of adenoviral-mediated siRNA against GRP78 gene on adenosine-induced apoptosis in human hepatoma HepG2 cells.
Carcinoma, Hepatocellular
Ethanol facilitates HCV replication via upregulation of GW182 and HSP90 in human hepatoma cells.
Carcinoma, Hepatocellular
Exogenous H2S promotes cancer progression by activating JAK2/STAT3 signaling pathway in esophageal EC109 cells.
Carcinoma, Hepatocellular
Exosomes derived from siRNA against GRP78 modified bone-marrow-derived mesenchymal stem cells suppress Sorafenib resistance in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Exploiting bilosomes for delivering bioactive polysaccharide isolated from Enteromorpha intestinalis for hacking hepatocellular carcinoma.
Carcinoma, Hepatocellular
Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Expression of different members of heat shock protein 70 gene family in liver and hepatomas.
Carcinoma, Hepatocellular
Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules.
Carcinoma, Hepatocellular
Expression of mortalin detected in human liver cancer by tissue microarrays.
Carcinoma, Hepatocellular
Extracellular HSP70-peptide complexes promote the proliferation of hepatocellular carcinoma cells via TLR2/4/JNK1/2MAPK pathway.
Carcinoma, Hepatocellular
Extracellular HSP70/HSP70-PCs regulate hepatocarcinoma cell migration and invasion via RhoA.
Carcinoma, Hepatocellular
Flavone antagonists bind competitively with 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor but inhibit nuclear uptake and transformation.
Carcinoma, Hepatocellular
Gas generating microspheres for immediate release of Hsp90 inhibitor aiming at postembolization hypoxia in transarterial chemoembolization therapy of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Gel-based proteomics of liver cancer progression in rat.
Carcinoma, Hepatocellular
Generation of murine CTL by a hepatitis B virus-specific peptide and evaluation of the adjuvant effect of heat shock protein glycoprotein 96 and its terminal fragments.
Carcinoma, Hepatocellular
Genetic variants of heat shock protein A1L2437 and A1B1267 as possible risk factors for hepatocellular carcinoma in India.
Carcinoma, Hepatocellular
Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.
Carcinoma, Hepatocellular
Glucose-Regulated Protein 78 (GRP78) Mediated the Efficacy to Curcumin Treatment on Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Glucose-Regulated Protein 78 (GRP78) Silencing Enhances Cell Migration but Does Not Influence Cell Proliferation in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Glutamine Synthetase, Heat shock Protein-70, and Glypican-3 in Intrahepatic Cholangiocarcinoma and Tumors Metastatic to Liver.
Carcinoma, Hepatocellular
Granulin-epithelin precursor interacts with 78-kDa glucose-regulated protein in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Growth factors acting via tyrosine kinase receptors induce HSP90 alpha gene expression.
Carcinoma, Hepatocellular
GRP78 activates the Wnt/HOXB9 pathway to promote invasion and metastasis of hepatocellular carcinoma by chaperoning LRP6.
Carcinoma, Hepatocellular
GRP78 and GAL3, differentially regulated by lymph node homogenates, as potential biomarkers for lymph node metastasis in mouse hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS axis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
GRP78 Promotes Hepatocellular Carcinoma proliferation by increasing FAT10 expression through the NF-?B pathway.
Carcinoma, Hepatocellular
Grp78 promotes the invasion of hepatocellular carcinoma.
Carcinoma, Hepatocellular
HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Heat Shock Protein 12A Is a Novel PCNA-binding Protein and Promotes Hepatocellular Carcinoma Growth.
Carcinoma, Hepatocellular
Heat shock protein 20 (HSPB6) regulates apoptosis in human hepatocellular carcinoma cells: Direct association with Bax.
Carcinoma, Hepatocellular
Heat shock protein 20 (HSPB6) regulates TNF-?-induced intracellular signaling pathway in human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Heat shock protein 22 (HSPB8) reduces the migration of hepatocellular carcinoma cells through the suppression of the phosphoinositide 3-kinase (PI3K)/AKT pathway.
Carcinoma, Hepatocellular
Heat shock protein 27 mediates the effect of 1,3,5-trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Heat Shock Protein 60 in Hepatocellular Carcinoma: Insights and Perspectives.
Carcinoma, Hepatocellular
Heat shock protein 70 chaperoned alpha-fetoprotein in human hepatocellular carcinoma cell line BEL-7402.
Carcinoma, Hepatocellular
Heat shock protein 70 downregulation inhibits proliferation, migration and tumorigenicity in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Heat shock protein 70 positively regulates transforming growth factor-?-induced hepatocellular carcinoma cell migration via the AKT signaling pathway.
Carcinoma, Hepatocellular
Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.
Carcinoma, Hepatocellular
Heat shock protein 70 silencing enhances apoptosis inducing factor-mediated cell death in hepatocellular carcinoma HepG(2) cells.
Carcinoma, Hepatocellular
Heat shock protein 90 inhibition abrogates hepatocellular cancer growth through cdc2-mediated G(2)/M cell cycle arrest and apoptosis.
Carcinoma, Hepatocellular
Heat shock protein 90 promotes RNA helicase DDX5 accumulation and exacerbates hepatocellular carcinoma by inhibiting autophagy.
Carcinoma, Hepatocellular
Heat Shock Protein 90?-Dependent B-Cell-2-Associated Transcription Factor 1 Promotes Hepatocellular Carcinoma Proliferation by Regulating MYC Proto-Oncogene c-MYC mRNA Stability.
Carcinoma, Hepatocellular
Heat Shock Protein A1B 1267 Polymorphism Is Highly Associated With Risk and Prognosis of Hepatocellular Carcinoma: A Case-Control Study.
Carcinoma, Hepatocellular
Heat Shock Protein Beta 1 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Heat shock protein expression and autophagy after incomplete thermal ablation and their correlation.
Carcinoma, Hepatocellular
Heat shock protein expression induced by percutaneous radiofrequency ablation of hepatocellular carcinoma in vivo.
Carcinoma, Hepatocellular
Heat shock protein-guided dual-mode CT/MR imaging of orthotopic hepatocellular carcinoma tumor.
Carcinoma, Hepatocellular
Heat shock, protein synthesis and ribosomal protein S6 phosphorylation in vitro in Yoshida AH 130 ascites hepatoma cells.
Carcinoma, Hepatocellular
Hep88 mAb-initiated paraptosis-like PCD pathway in hepatocellular carcinoma cell line through the binding of mortalin (HSPA9) and alpha-enolase.
Carcinoma, Hepatocellular
Hepatocellular carcinoma arising in adenoma: similar immunohistochemical and cytogenetic features in adenoma and hepatocellular carcinoma portions of the tumor.
Carcinoma, Hepatocellular
Hepatoma cells adapted to proliferate under normally lethal hyperthermic stress conditions show rapid decay of thermoresistance and heat shock protein synthesis when returned to 37 degrees C.
Carcinoma, Hepatocellular
Hsp27 Acts as a Master Molecular Chaperone and Plays an Essential Role in Hepatocellular Carcinoma Progression.
Carcinoma, Hepatocellular
HSP27 expression levels are associated with the sensitivity of hepatocellular carcinoma cells to 17-allylamino-17-demethoxygeldanamycin.
Carcinoma, Hepatocellular
Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma.
Carcinoma, Hepatocellular
HSP90 and SIRT3 expression in hepatocellular carcinoma and their effect on invasive capability of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Hsp90 inhibitor 17-AAG sensitizes Bcl-2 inhibitor (-)-gossypol by suppressing ERK-mediated protective autophagy and Mcl-1 accumulation in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Hsp90 inhibitor geldanamycin enhances the antitumor efficacy of enediyne lidamycin in association with reduced DNA damage repair.
Carcinoma, Hepatocellular
Hsp90 Inhibitor STA9090 Sensitizes Hepatocellular Carcinoma to Hyperthermia-Induced DNA Damage by Suppressing DNA-PKcs Protein Stability and mRNA Transcription.
Carcinoma, Hepatocellular
HSP90 inhibits apoptosis and promotes growth by regulating HIF-1? abundance in hepatocellular carcinoma.
Carcinoma, Hepatocellular
HSP90 interacts with HMGCR and promotes the progression of hepatocellular carcinoma.
Carcinoma, Hepatocellular
HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
Carcinoma, Hepatocellular
HSP90? combined with AFP and TK1 improved the diagnostic value for hepatocellular carcinoma.
Carcinoma, Hepatocellular
Human hepatoma cell line (HepG2) cellular response to hypothermic stress with recovery. Induction of Hsp70, Hsp60 and Hsf1 expression.
Carcinoma, Hepatocellular
Hypoxia attenuates Hsp90 inhibitor 17-DMAG-induced cyclin B1 accumulation in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Hypoxia induces HSP 70 gene expression in human hepatoma (HEP G2) cells.
Carcinoma, Hepatocellular
Identification of a Promiscuous Epitope Peptide Derived From HSP70.
Carcinoma, Hepatocellular
Identification of Tumor Antigen AF20 as Glycosylated Transferrin Receptor 1 in Complex with Heat Shock Protein 90 and/or Transporting ATPase.
Carcinoma, Hepatocellular
Immunoexpression of Heat Shock Protein 70, Glypican 3, Glutamine Synthetase, and Beta-Catenin in Hepatocellular Carcinoma After Liver Transplantation: Association Between Positive Glypican 3 and Beta-Catenin With the Presence of Larger Nodules.
Carcinoma, Hepatocellular
In silico analysis of the binding properties of solasonine to mortalin and p53, and in vitro pharmacological studies of its apoptotic and cytotoxic effects on human HepG2 and Hep3b hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Increase of thermoresistance after growth stimulation of resting Reuber H35 hepatoma cells. Alteration of nuclear characteristics, non-histone chromosomal protein phosphorylation and basal heat shock protein synthesis.
Carcinoma, Hepatocellular
Increased expression of heat shock protein-binding protein 1 and heat shock protein 70 in human hepatocellular carcinoma tissues.
Carcinoma, Hepatocellular
Induction of anoikis by sodium arsenite in rat hepatoma FGC4 cells: comparison with cadmium chloride and implications for assessment of regulation of heat shock protein 70.
Carcinoma, Hepatocellular
Induction of mitochondrial chaperonin, hsp60, by cadmium in human hepatoma cells.
Carcinoma, Hepatocellular
Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin.
Carcinoma, Hepatocellular
Induction of plasminogen activator inhibitor 1 biosynthesis by hyperthermia.
Carcinoma, Hepatocellular
Inhibition of Hsp27 and Hsp40 potentiates 5-fluorouracil and carboplatin mediated cell killing in hepatoma cells.
Carcinoma, Hepatocellular
Insulin Dependant Gene Expression of Heat Shock Protein 60 in H4IIE Hepatoma Cells.
Carcinoma, Hepatocellular
Interaction between heat shock protein 72 and alpha-fetoprotein in human hepatocellular carcinomas.
Carcinoma, Hepatocellular
Interleukin 6 activates heat-shock protein 90 beta gene expression.
Carcinoma, Hepatocellular
Intracellular association between UDP-glucose:glycoprotein glucosyltransferase and an incompletely folded variant of alpha1-antitrypsin.
Carcinoma, Hepatocellular
Introducing differential expression of human heat shock protein 27 in hepatocellular carcinoma: moving toward identification of cancer biomarker.
Carcinoma, Hepatocellular
Involvement and Targeted Intervention of Mortalin-Regulated Proteome Phosphorylated-Modification in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Involvement of heat-shock protein 70 and P53 proteins in attenuation of UVC-induced apoptosis by thermal stress in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3.
Carcinoma, Hepatocellular
Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression.
Carcinoma, Hepatocellular
Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling.
Carcinoma, Hepatocellular
Molecular chaperone CCT3 supports proper mitotic progression and cell proliferation in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Mortalin stabilizes CD151-depedent tetraspanin-enriched microdomains and implicates in the progression of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy.
Carcinoma, Hepatocellular
Nanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78.
Carcinoma, Hepatocellular
No association between the haplotypic block in the 3' UTR of GRP78 and risk of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Non-specific protein modifications by a phytochemical induce heat shock response for self-defense.
Carcinoma, Hepatocellular
Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial.
Carcinoma, Hepatocellular
Novel celastrol derivatives inhibit the growth of hepatocellular carcinoma patient-derived xenografts.
Carcinoma, Hepatocellular
Overexpression of heat shock protein HSP90AA1 and translocase of the outer mitochondrial membrane TOM34 in HCV-induced hepatocellular carcinoma: A pilot study.
Carcinoma, Hepatocellular
Overexpression of Mortalin in hepatocellular carcinoma and its relationship with angiogenesis and epithelial to mesenchymal transition.
Carcinoma, Hepatocellular
Phosphorylated Heat Shock Protein 20 (HSPB6) Regulates Transforming Growth Factor-?-Induced Migration and Invasion of Hepatocellular Carcinoma Cells.
Carcinoma, Hepatocellular
Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase.
Carcinoma, Hepatocellular
Prenylation differentially inhibits insulin-dependent immediate early gene mRNA expression.
Carcinoma, Hepatocellular
Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model.
Carcinoma, Hepatocellular
PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability.
Carcinoma, Hepatocellular
Prospective validation of an immunohistochemical panel (glypican 3, heat shock protein 70 and glutamine synthetase) in liver biopsies for diagnosis of very early hepatocellular carcinoma.
Carcinoma, Hepatocellular
Protective Effects of Alisma orientale Extract against Hepatic Steatosis via Inhibition of Endoplasmic Reticulum Stress.
Carcinoma, Hepatocellular
Protein kinase C delta regulates the phosphorylation of heat shock protein 27 in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Proteomic Characterization of Annexin l (ANX1) and Heat Shock Protein 27 (HSP27) as Biomarkers for Invasive Hepatocellular Carcinoma Cells.
Carcinoma, Hepatocellular
Proteomic Profile of Sorafenib Resistance in Hepatocellular Carcinoma; GRP78 Expression Is Associated With Inferior Response to Sorafenib.
Carcinoma, Hepatocellular
Proteomic profiling of heat shock protein 70 family members as biomarkers for hepatitis C virus-related hepatocellular carcinoma.
Carcinoma, Hepatocellular
Purification of heat shock protein 70-associated tumor peptides and their antitumor immunity to hepatoma in mice.
Carcinoma, Hepatocellular
Regulation of HSP27 on NF-kappaB pathway activation may be involved in metastatic hepatocellular carcinoma cells apoptosis.
Carcinoma, Hepatocellular
Regulation of Molecular Chaperone GRP78 by Hepatitis B Virus: Control of Viral Replication and Cell Survival.
Carcinoma, Hepatocellular
Reversible ADP-ribosylation of the 78 kDa glucose-regulated protein.
Carcinoma, Hepatocellular
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer.
Carcinoma, Hepatocellular
Role of the aryl hydrocarbon receptor nuclear translocator protein in aryl hydrocarbon (dioxin) receptor action.
Carcinoma, Hepatocellular
Role of the novel HSP90 inhibitor AUY922 in hepatocellular carcinoma: Potential for therapy.
Carcinoma, Hepatocellular
S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase.
Carcinoma, Hepatocellular
Serum heat shock protein 27 levels in patients with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Silencing of Glucose-Regulated Protein 78 (GRP78) Enhances Cell Migration Through the Upregulation of Vimentin in Hepatocellular Carcinoma Cells.
Carcinoma, Hepatocellular
Single nucleotide polymorphism of rs430397 in the fifth intron of GRP78 gene and clinical relevance of primary hepatocellular carcinoma in Han Chinese: risk and prognosis.
Carcinoma, Hepatocellular
Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2?/ATF4/CHOP Pathway.
Carcinoma, Hepatocellular
Strategic shotgun proteomics approach for efficient construction of an expression map of targeted protein families in hepatoma cell lines.
Carcinoma, Hepatocellular
Structural analyses of the PKA RII? holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Carcinoma, Hepatocellular
Suppression by heat shock protein 20 of hepatocellular carcinoma cell proliferation via inhibition of the mitogen-activated protein kinases and AKT pathways.
Carcinoma, Hepatocellular
Targeted inhibition of mitochondrial Hsp90 induces mitochondrial elongation in Hep3B hepatocellular carcinoma cells undergoing apoptosis by increasing the ROS level.
Carcinoma, Hepatocellular
Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing p53-mediated apoptosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Targeting heat shock protein 90 with non-quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.
Carcinoma, Hepatocellular
Targeting HSP60 by subcutaneous injections of jetPEI/HSP60-shRNA destabilizes cytoplasmic survivin and inhibits hepatocellular carcinoma growth.
Carcinoma, Hepatocellular
Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma.
Carcinoma, Hepatocellular
The 3' UTR Variants in the GRP78 Are Not Associated with Overall Survival in Resectable Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
The anti-cancer flavonoid chrysin induces the unfolded protein response in hepatoma cells.
Carcinoma, Hepatocellular
The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
The association of variants in PNPLA3 and GRP78 and the risk of developing hepatocellular carcinoma in an Italian population.
Carcinoma, Hepatocellular
The cell surface GRP78 facilitates the invasion of hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
The Clinical Value of HSP60 in Digestive System Cancers: a Systematic Review and Meta-Analysis.
Carcinoma, Hepatocellular
The clinicopathological significance of heat shock protein 70 and glutamine synthetase expression in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The Escherichia coli Subtilase Cytotoxin A Subunit Specifically Cleaves Cell-Surface GRP78 and Abolishes COOH-Terminal-Dependent Signaling.
Carcinoma, Hepatocellular
The Hsp90 inhibitor SNX-2112 induces apoptosis of human hepatocellular carcinoma cells: The role of ER stress.
Carcinoma, Hepatocellular
The HSP90 inhibitor, XL888, enhanced cell apoptosis via downregulating STAT3 after insufficient radiofrequency ablation in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The ménage à trois of autophagy, lipid droplets and liver disease.
Carcinoma, Hepatocellular
The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated ?2M.
Carcinoma, Hepatocellular
The role of heat shock protein 27 expression in hepatocellular carcinoma in Japan: special reference to the difference between hepatitis B and C.
Carcinoma, Hepatocellular
The role of HSP90 molecular chaperones in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells.
Carcinoma, Hepatocellular
The rs391957 variant cis-regulating oncogene GRP78 expression contributes to the risk of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Tissue Biomarkers in Hepatocellular Tumors: Which, When, and How.
Carcinoma, Hepatocellular
Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo-Independent Regulation of Heat Shock Protein 70 Family Members.
Carcinoma, Hepatocellular
Transcriptional signaling from membrane raft-associated glucocorticoid receptor.
Carcinoma, Hepatocellular
Transcriptomic analysis reveals that heat shock protein 90? is a potential diagnostic and prognostic biomarker for cancer.
Carcinoma, Hepatocellular
Transcriptomic characterization of fibrolamellar hepatocellular carcinoma.
Carcinoma, Hepatocellular
Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: role of cell-cycle arrest and GRP78.
Carcinoma, Hepatocellular
Upregulation of heat shock protein 70 and the differential protein expression induced by tumor necrosis factor-alpha enhances migration and inhibits apoptosis of hepatocellular carcinoma cell HepG2.
Carcinoma, Hepatocellular
Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.
Carcinoma, Hepatocellular
[Construction of underexpression HSP90alpha and overexpression HSP90beta human hepatoma cell line HepG2].
Carcinoma, Hepatocellular
[Inhibition of HSP70-2 expression by RNA interference induces apoptosis of human hepatocellular carcinoma cells.]
Carcinoma, Hepatocellular
[Overexpression of heat shock protein 70 and spontaneous cancer cell apoptosis in hepatocellular carcinoma]
Carcinoma, Hepatocellular
[Regulatory mechanism of heat shock protein 90 on autophagy-related transcription factor EB in human hepatocellular carcinoma cells].
Carcinoma, Hepatocellular
[Relationship of heat shock protein 70-2 gene polymorphism with hepatocellular carcinoma]
Carcinoma, Hepatocellular
[Stable isotope labeling and parallel reaction monitoring-based proteomic quantification for biomarker screening and validation of hepatocellular carcinoma].
Carcinoma, Hepatocellular
[The detection of heat shock protein gp96 in primary hepatocellular carcinoma]
Carcinoma, Intraductal, Noninfiltrating
Elevated expression of nuclear Hsp90 in invasive breast tumors.
Carcinoma, Intraductal, Noninfiltrating
Heat shock protein 27 overexpression in breast cancer lymph node metastasis.
Carcinoma, Intraductal, Noninfiltrating
Hsp90 in the continuum of breast ductal carcinogenesis: Evaluation in precursors, preinvasive and ductal carcinoma lesions.
Carcinoma, Intraductal, Noninfiltrating
Proteomics-based identification of HSP60 as a tumor-associated antigen in early stage breast cancer and ductal carcinoma in situ.
Carcinoma, Intraductal, Noninfiltrating
Serum levels of HSP90 in the continuum of breast ductal and lobular lesions.
Carcinoma, Intraductal, Noninfiltrating
Systematic analyses of key genes and pathways in the development of invasive breast cancer.
Carcinoma, Intraductal, Noninfiltrating
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast.
Carcinoma, Lewis Lung
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice.
Carcinoma, Lewis Lung
Heat shock protein 70 is acute phase reactant: response elicited by tumor treatment with photodynamic therapy.
Carcinoma, Lewis Lung
The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit.
Carcinoma, Lobular
BAG-1/SODD, HSP70 and HSP90 are potential prognostic markers of poor survival in node-negative breast carcinoma.
Carcinoma, Lobular
Decreased Hsp90 expression in infiltrative lobular carcinoma: an immunohistochemical study.
Carcinoma, Lobular
Heat shock protein 90 (hsp90) expression and breast cancer.
Carcinoma, Lobular
Serum levels of HSP90 in the continuum of breast ductal and lobular lesions.
Carcinoma, Non-Small-Cell Lung
19P Comparative effectiveness analysis of HSP90 inhibitors in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
Carcinoma, Non-Small-Cell Lung
A Randomized, Double-Blinded, Phase II Trial of Carboplatin and Pemetrexed with or without Apatorsen (OGX-427) in Patients with Previously Untreated Stage IV Non-Squamous-Non-Small-Cell Lung Cancer: The SPRUCE Trial.
Carcinoma, Non-Small-Cell Lung
Anti-tumor selectivity of a novel tubulin and HSP90 dual-targeting inhibitor in non-small cell lung cancer models.
Carcinoma, Non-Small-Cell Lung
Antibodies to HSP70 and HSP90 in serum in non-small cell lung cancer patients.
Carcinoma, Non-Small-Cell Lung
Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non-Small Cell Lung Cancer Cell Lines and Tumor Models.
Carcinoma, Non-Small-Cell Lung
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.
Carcinoma, Non-Small-Cell Lung
Aspirin potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer by targeting GRP78 activity.
Carcinoma, Non-Small-Cell Lung
Author Correction: Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device.
Carcinoma, Non-Small-Cell Lung
Celastrol induces apoptosis in gefitinib-resistant non-small cell lung cancer cells via caspases-dependent pathways and Hsp90 client protein degradation.
Carcinoma, Non-Small-Cell Lung
Chalcone-templated Hsp90 inhibitors and their effects on gefitinib resistance in non-small cell lung cancer (NSCLC).
Carcinoma, Non-Small-Cell Lung
Circulating heat shock protein 27 as a biomarker for the differentiation of patients with lung cancer and healthy controls--a clinical comparison of different enzyme linked immunosorbent assays.
Carcinoma, Non-Small-Cell Lung
Clinicopathological and prognostic significance of heat shock protein 27 (HSP27) expression in non-small cell lung cancer: a systematic review and meta-analysis.
Carcinoma, Non-Small-Cell Lung
Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Complex Crystal Structure Determination and in vitro Anti-non-small Cell Lung Cancer Activity of Hsp90 N Inhibitor SNX-2112.
Carcinoma, Non-Small-Cell Lung
Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Development of a novel Hsp90 inhibitor NCT-50 as a potential anticancer agent for the treatment of non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Discovery of 2',4'-dimethoxychalcone as a Hsp90 inhibitor and its effect on iressa-resistant non-small cell lung cancer (NSCLC).
Carcinoma, Non-Small-Cell Lung
Discovery of hybrid Hsp90 inhibitors and their anti-neoplastic effects against gefitinib-resistant non-small cell lung cancer (NSCLC).
Carcinoma, Non-Small-Cell Lung
Distinct prognostic roles of HSPB1 expression in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Down-regulation of ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 protein (XRCC1) expression by Hsp90 inhibition enhances the gefitinib-induced cytotoxicity in human lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in human non-small-cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers.
Carcinoma, Non-Small-Cell Lung
Effect of BIS depletion on HSF1-dependent transcriptional activation in A549 non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
EML4-ALK fusions: propelling cancer but creating exploitable chaperone dependence.
Carcinoma, Non-Small-Cell Lung
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Carcinoma, Non-Small-Cell Lung
Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Expression of heat shock protein 70 and 27 in non-small cell lung cancer and its clinical significance.
Carcinoma, Non-Small-Cell Lung
Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis.
Carcinoma, Non-Small-Cell Lung
GRP78, intronic polymorphisms, and pharmacogenomics in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Heat Shock Protein 70 (Hsp70) Peptide Activated Natural Killer (NK) Cells for the Treatment of Patients with Non-Small Cell Lung Cancer (NSCLC) after Radiochemotherapy (RCTx) - From Preclinical Studies to a Clinical Phase II Trial.
Carcinoma, Non-Small-Cell Lung
Heat shock protein 70 as a predictive marker for platinum-based adjuvant chemotherapy in patients with resected non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Heat shock protein 72 does not modulate ionizing radiation-induced apoptosis in U1810 non-small cell lung carcinoma cells.
Carcinoma, Non-Small-Cell Lung
Heat Shock Protein 90 (Hsp90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivo.
Carcinoma, Non-Small-Cell Lung
Heat shock protein antagonists in early stage clinical trials for NSCLC.
Carcinoma, Non-Small-Cell Lung
Heat shock protein B6 potently increases non-small cell lung cancer growth.
Carcinoma, Non-Small-Cell Lung
Heat Shock Proteins: A Potential Anticancer Target.
Carcinoma, Non-Small-Cell Lung
HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
HSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
HSP90 inhibition induces cytotoxicity via down-regulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Hsp90 Inhibitor Ganetespib Sensitizes Non-Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation.
Carcinoma, Non-Small-Cell Lung
HSP90 inhibitor, DMAG, synergizes with radiation of lung cancer cells by interfering with base excision and ATM-mediated DNA repair.
Carcinoma, Non-Small-Cell Lung
Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines.
Carcinoma, Non-Small-Cell Lung
HSPB1 Gene Polymorphisms Predict Risk of Mortality for US Patients After Radio(chemo)therapy for Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target.
Carcinoma, Non-Small-Cell Lung
Involvement of calcium in the differential induction of heat shock protein 70 by heat shock protein 90 inhibitors, geldanamycin and radicicol, in human non-small cell lung cancer H460 cells.
Carcinoma, Non-Small-Cell Lung
Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis.
Carcinoma, Non-Small-Cell Lung
Luminespib plus pemetrexed in patients with non-squamous non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.
Carcinoma, Non-Small-Cell Lung
Mortalin overexpression predicts poor prognosis in early stage of non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Novel Heat Shock Protein 90 Inhibitors Suppress P-Glycoprotein Activity and Overcome Multidrug Resistance in Cancer Cells.
Carcinoma, Non-Small-Cell Lung
Novel Hsp90 Inhibitor C086 Potently Inhibits Non-Small Cell Lung Cancer Cells As A Single Agent Or In Combination With Gefitinib.
Carcinoma, Non-Small-Cell Lung
Nuclear Accumulation of Heat-shock Protein 90 Is Associated with Poor Survival and Metastasis in Patients with Non-small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients.
Carcinoma, Non-Small-Cell Lung
P-glycoprotein confers acquired resistance to 17-DMAG in lung cancers with an ALK rearrangement.
Carcinoma, Non-Small-Cell Lung
Pifithrin-? is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70.
Carcinoma, Non-Small-Cell Lung
Prognostic value of the mRNA expression of members of the HSP90 family in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Reversed expression of GRIM-1 and GRP78 in human non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Sensitization of lung cancer cells by altered dimerization of HSP27.
Carcinoma, Non-Small-Cell Lung
Serum GRP78 as a Tumor Marker and Its Prognostic Significance in Non-Small Cell Lung Cancers: A Retrospective Study.
Carcinoma, Non-Small-Cell Lung
Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models.
Carcinoma, Non-Small-Cell Lung
Targeted Inhibition of the Molecular Chaperone Hsp90 Overcomes ALK Inhibitor Resistance in Non-Small Cell Lung Cancer.
Carcinoma, Non-Small-Cell Lung
Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells.
Carcinoma, Non-Small-Cell Lung
Targeting KRAS-mutant non-small cell lung cancer with the Hsp90 inhibitor ganetespib.
Carcinoma, Non-Small-Cell Lung
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells.
Carcinoma, Non-Small-Cell Lung
The heat shock protein 90 inhibitor, AT13387, displays a long duration of action in vitro and in vivo in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
The HSP90 inhibitor ganetespib potentiates the antitumor activity of EGFR tyrosine kinase inhibition in mutant and wild-type non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
The Hsp90 inhibitor IPI-504 rapidly lowers EML4-ALK levels and induces tumor regression in ALK-driven NSCLC models.
Carcinoma, Non-Small-Cell Lung
The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth.
Carcinoma, Non-Small-Cell Lung
The HSP90 inhibitor, NVP-AUY922, attenuates intrinsic PI3K inhibitor resistance in KRAS-mutant non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
The HSP90 inhibitor, NVP-AUY922, sensitizes KRAS-mutant non-small cell lung cancer with intrinsic resistance to MEK inhibitor, trametinib.
Carcinoma, Non-Small-Cell Lung
Therapeutic uses of HSP90 inhibitors in Non-Small Cell Lung Carcinoma (NSCLC).
Carcinoma, Non-Small-Cell Lung
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.
Carcinoma, Non-Small-Cell Lung
Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90-Targeted Therapy.
Carcinoma, Non-Small-Cell Lung
[Relationship between chemosensitivity in vitro and the expression of GRP78 in non-small cell lung cancer.]
Carcinoma, Ovarian Epithelial
18?-Glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.
Carcinoma, Ovarian Epithelial
Combined Effect of Hsp90 Inhibitor Geldanamycin and Parthenolide via Reactive Oxygen Species-Mediated Apoptotic Process on Epithelial Ovarian Cancer Cells.
Carcinoma, Ovarian Epithelial
Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries.
Carcinoma, Ovarian Epithelial
Heat shock protein 27: a potential biomarker of peritoneal metastasis in epithelial ovarian cancer?
Carcinoma, Ovarian Epithelial
Heat shock protein 27: an independent prognostic indicator of survival in patients with epithelial ovarian carcinoma.
Carcinoma, Ovarian Epithelial
HSPA1A, HSPA1L and TRAP1 heat shock genes may be associated with prognosis in ovarian epithelial cancer.
Carcinoma, Ovarian Epithelial
Immunohistochemical detection of HSP60-expression in human ovarian cancer. Correlation with survival in a series of 247 patients.
Carcinoma, Ovarian Epithelial
Increased expression of heat shock protein 27 correlates with peritoneal metastasis in epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Carcinoma, Ovarian Epithelial
Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors.
Carcinoma, Ovarian Epithelial
Papers to Appear in Forthcoming Issues
Carcinoma, Ovarian Epithelial
Quantitative assessment of serum heat shock protein 27 for the diagnosis of epithelial ovarian cancer using targeted proteomics coupled with immunoaffinity enrichment.
Carcinoma, Ovarian Epithelial
Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins.
Carcinoma, Ovarian Epithelial
[Isolation, identification and clinical significance of ascites-derived exosomes from patients with ovarian epithelial cancer]
Carcinoma, Renal Cell
A hsp70-2 mutation recognized by CTL on a human renal cell carcinoma.
Carcinoma, Renal Cell
A phase II trial of 17-(Allylamino)-17-demethoxygeldanamycin in patients with papillary and clear cell renal cell carcinoma.
Carcinoma, Renal Cell
Characterization of heat shock protein 27 phosphorylation sites in renal cell carcinoma.
Carcinoma, Renal Cell
Clinical Implications of HSC70 Expression in Clear Cell Renal Cell Carcinoma.
Carcinoma, Renal Cell
Combination Treatment of Renal Cell Carcinoma with Belinostat and 5-Fluorouracil: A Role for Oxidative Stress Induced DNA Damage and HSP90 Regulated Thymidine Synthase.
Carcinoma, Renal Cell
Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation.
Carcinoma, Renal Cell
Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma.
Carcinoma, Renal Cell
Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Carcinoma, Renal Cell
Effects of the novel heat shock protein 90 inhibitor AUY922 in renal cell carcinoma ACHN and 786-O cells.
Carcinoma, Renal Cell
EIF3D promotes sunitinib resistance of renal cell carcinoma by interacting with GRP78 and inhibiting its degradation.
Carcinoma, Renal Cell
Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110.
Carcinoma, Renal Cell
Expression of heat shock protein 27 in human renal cell carcinoma.
Carcinoma, Renal Cell
Expression of heat shock protein 70 in renal cell carcinoma and its relation to tumor progression and prognosis.
Carcinoma, Renal Cell
Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients.
Carcinoma, Renal Cell
GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma.
Carcinoma, Renal Cell
Heat shock protein (HSP72) surface expression enhances the lysis of a human renal cell carcinoma by IL-2 stimulated NK cells.
Carcinoma, Renal Cell
Heat shock protein expression and anti-heat shock protein reactivity in renal cell carcinoma.
Carcinoma, Renal Cell
Heat-shock protein 70 as a tumor antigen for in vitro dendritic cell pulsing in renal cell carcinoma cases.
Carcinoma, Renal Cell
HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.
Carcinoma, Renal Cell
HSP60 silencing promotes Warburg-like phenotypes and switches the mitochondrial function from ATP production to biosynthesis in ccRCC cells.
Carcinoma, Renal Cell
Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway.
Carcinoma, Renal Cell
Inhibition of Cancer Cell Growth by GRP78 siRNA Lipoplex via Activation of Unfolded Protein Response.
Carcinoma, Renal Cell
Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2? pathway.
Carcinoma, Renal Cell
MicroRNA-30a-5p Inhibits the Growth of Renal Cell Carcinoma by Modulating GRP78 Expression.
Carcinoma, Renal Cell
Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.
Carcinoma, Renal Cell
Quality of life in patients with metastatic renal cell carcinoma participating in a phase I trial of an autologous tumor-derived vaccine.
Carcinoma, Renal Cell
Quantitative score modulation of HSP90 and HSP27 in clear cell renal cell carcinoma.
Carcinoma, Renal Cell
Significance of heat shock protein-27 expression in patients with renal cell carcinoma.
Carcinoma, Renal Cell
Single-Cell Sequencing to Identify Six Heat Shock Protein (HSP) Genes-Mediated Progression Subtypes of Clear Cell Renal Cell Carcinoma.
Carcinoma, Renal Cell
Upregulation of GRP78 in Renal Cell Carcinoma and Its Significance.
Carcinoma, Renal Cell
[Generation of specific cytotoxicity T lymphocytes induced by tumor-derived heat shock protein 90-peptide complexes in vitro]
Carcinoma, Squamous Cell
A comparison of cell survival and heat shock protein expression after radiation in normal dermal fibroblasts, microvascular endothelial cells, and different head and neck squamous carcinoma cell lines.
Carcinoma, Squamous Cell
A novel intronic circular RNA, circGNG7, inhibits head and neck squamous cell carcinoma progression by blocking the phosphorylation of heat shock protein 27 at Ser78 and Ser82.
Carcinoma, Squamous Cell
Analysis of HSP90 Expression Is Valuable in the Differential Diagnosis of Ocular Surface Squamous Lesions.
Carcinoma, Squamous Cell
Antitumorigenic Effect of Hsp90 Inhibitor SNX-2112 on Tongue Squamous Cell Carcinoma is Enhanced by Low-Intensity Ultrasound.
Carcinoma, Squamous Cell
BIIB021, a novel HSP90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy.
Carcinoma, Squamous Cell
CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.
Carcinoma, Squamous Cell
Cell surface expression of 70 kDa heat shock protein in human oral dysplasia and squamous cell carcinoma: correlation with clinicopathological features.
Carcinoma, Squamous Cell
Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung.
Carcinoma, Squamous Cell
Chaperonin (HSP60) and annexin-2 are candidate biomarkers for non-small cell lung carcinoma.
Carcinoma, Squamous Cell
Characterization of proteins associated with heat shock protein hsp27 in the squamous cell carcinoma cell line A431.
Carcinoma, Squamous Cell
Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis.
Carcinoma, Squamous Cell
Diagnostic value of heat shock protein 90? and squamous cell carcinoma antigen in detection of cervical cancer.
Carcinoma, Squamous Cell
Differential expression of heat shock protein 27 in normal oral mucosa, oral epithelial dysplasia and squamous cell carcinoma.
Carcinoma, Squamous Cell
Differential Expression of Heat Shock Protein 27 in Oral Epithelial Dysplasias and Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Differential expression of Mr 70,000 heat shock protein in normal, premalignant, and malignant human uterine cervix.
Carcinoma, Squamous Cell
Down-regulation of epidermal growth factor receptor-signaling pathway by binding of GRP78/BiP to the receptor under glucose-starved stress conditions.
Carcinoma, Squamous Cell
Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma.
Carcinoma, Squamous Cell
Effect of 17-allylamino-17-demethoxygeldanamycin (17-AAG) on Akt protein expression is more effective in head and neck cancer cell lineages that retain PTEN protein expression.
Carcinoma, Squamous Cell
Effect of hypoxia on the expression of alphaB-crystallin in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.
Carcinoma, Squamous Cell
Effects of far infrared radiation by isotropic high-density carbon on the human oral mucosa.
Carcinoma, Squamous Cell
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Carcinoma, Squamous Cell
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions.
Carcinoma, Squamous Cell
Expression of Heat Shock Protein 105 in Cutaneous Squamous Cell Carcinoma: Correlation with Clinicopathological Characteristics.
Carcinoma, Squamous Cell
Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study.
Carcinoma, Squamous Cell
GRP78 induction by calcium ionophore potentiates photodynamic therapy using the mitochondrial targeting dye victoria blue BO.
Carcinoma, Squamous Cell
Heat shock protein 105 is overexpressed in squamous cell carcinoma and extramammary Paget disease but not in basal cell carcinoma.
Carcinoma, Squamous Cell
Heat shock protein 27 and p16 immunohistochemistry in cervical intraepithelial neoplasia and squamous cell carcinoma.
Carcinoma, Squamous Cell
Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Heat shock protein 70 and tumor-infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).
Carcinoma, Squamous Cell
Heat shock protein 70 is involved in malignant behaviors and chemosensitivities to cisplatin in cervical squamous cell carcinoma cells.
Carcinoma, Squamous Cell
Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis.
Carcinoma, Squamous Cell
Heat shock protein and p53 expression in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Heat shock protein expression in oral epithelial dysplasia and squamous cell carcinoma.
Carcinoma, Squamous Cell
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
HSP70: a promising target for laryngeal carcinoma radiaotherapy by inhibiting cleavage and degradation of nucleolin.
Carcinoma, Squamous Cell
Hsp90 inhibitor can inhibit UV carcinogenesis.
Carcinoma, Squamous Cell
HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Hsp90 inhibitors cause G2/M arrest associated with the reduction of Cdc25C and Cdc2 in lung cancer cell lines.
Carcinoma, Squamous Cell
Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.
Carcinoma, Squamous Cell
Induction of heat shock protein 70 inhibits NF-kappa-B in squamous cell carcinoma.
Carcinoma, Squamous Cell
Induction of the 72-kD heat shock protein in human skin melanoma and squamous cell carcinoma cell lines.
Carcinoma, Squamous Cell
Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model.
Carcinoma, Squamous Cell
mRNA levels of molecular chaperones hsp27, hsp60 and hsp70 in cisplatin resistant squamous cell carcinomas.
Carcinoma, Squamous Cell
Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells.
Carcinoma, Squamous Cell
Novel HSP90 Inhibitor NVP-AUY922 enhances the anti-tumor effect of temsirolimus against oral squamous cell carcinoma.
Carcinoma, Squamous Cell
Overexpression of endoplasmic reticulum stress-related proteins, XBP1s and GRP78, predicts poor prognosis in pulmonary adenocarcinoma.
Carcinoma, Squamous Cell
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix.
Carcinoma, Squamous Cell
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.
Carcinoma, Squamous Cell
Overexpression of the small heat shock protein, hsp27, confers resistance to hyperthermia, but not to oxidative stress and UV-induced cell death, in a stably transfected squamous cell carcinoma cell line.
Carcinoma, Squamous Cell
Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis.
Carcinoma, Squamous Cell
Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo.
Carcinoma, Squamous Cell
Promoter hypermethylation of the gene encoding heat shock protein B1 in oral squamous carcinoma cells.
Carcinoma, Squamous Cell
Protein Expression Profile using Two-Dimensional Gel Analysis in Squamous Cervical Cancer Patients.
Carcinoma, Squamous Cell
Serum antibody response to the heat shock protein 60 of Chlamydia trachomatis in women with developing cervical cancer.
Carcinoma, Squamous Cell
Sulfoxythiocarbamate S-4 inhibits HSP90 in human cutaneous squamous cell carcinoma cells.
Carcinoma, Squamous Cell
The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells.
Carcinoma, Squamous Cell
The release of Hsp70 from A431 carcinoma cells is mediated by secretory-like granules.
Carcinoma, Squamous Cell
The selective Hsp90 inhibitor BJ-B11 exhibits potent antitumor activity via induction of cell cycle arrest, apoptosis and autophagy in Eca-109 human esophageal squamous carcinoma cells.
Carcinoma, Squamous Cell
Topically Applied Hsp90 Inhibitor 17AAG Inhibits UVR-Induced Cutaneous Squamous Cell Carcinomas.
Carcinoma, Squamous Cell
Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer.
Carcinoma, Squamous Cell
Two-dimensional gel analysis of protein expression profile in squamous cervical cancer patients.
Carcinoma, Squamous Cell
[Biology behavior of head and neck squamous cell cancer cells changes after knocking down heat shock protein 27].
Carcinoma, Squamous Cell
[Influence of the expression of heat shock protein 70 in maxillofacial squamous cell carcinoma by thermochemotherapy]
Carcinoma, Squamous Cell
[Screening of differentially expressed proteins from human esophageal cancer and esophageal tissues by two-dimensional difference gel electrophoresis and mass spectrometry]
Carcinoma, Transitional Cell
Heat shock protein 70 expression in relation to apoptosis in primary bladder transitional cell carcinoma.
Carcinoma, Transitional Cell
Heat shock proteins HSP27, HSP60, HSP70, and HSP90: expression in bladder carcinoma.
Carcinoma, Transitional Cell
Hsp-27 has no diagnostic or prognostic significance in prostate or bladder cancers.
Carcinoma, Verrucous
Expression of p53, MDM2, p21, heat shock protein 70, and HPV 16/18 E6 proteins in oral verrucous carcinoma and oral verrucous hyperplasia.
Cardio-Renal Syndrome
Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis.
Cardiomegaly
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy.
Cardiomegaly
Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy.
Cardiomegaly
Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure.
Cardiomegaly
Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway.
Cardiomegaly
Extracellular heat shock protein HSC70 protects against lipopolysaccharide-induced hypertrophic responses in rat cardiomyocytes.
Cardiomegaly
GRP78 (Glucose-Regulated Protein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4).
Cardiomegaly
Heat shock protein 90 regulates I?B kinase complex and NF-?B activation in angiotensin II-induced cardiac cell hypertrophy.
Cardiomegaly
Heat-shock protein 90 modulates cardiac ventricular hypertrophy via activation of MAPK pathway.
Cardiomegaly
HSP27 locus cosegregates with left ventricular mass independently of blood pressure.
Cardiomegaly
Hsp90/Cdc37 assembly modulates TGF? receptor-II to act as a profibrotic regulator of TGF? signaling during cardiac hypertrophy.
Cardiomegaly
Inhibition of heat shock protein 70 blocks the development of cardiac hypertrophy by modulating the phosphorylation of histone deacetylase 2.
Cardiomegaly
Intracellular or extracellular heat shock protein 70 differentially regulates cardiac remodelling in pressure overload mice.
Cardiomegaly
L-arginine restores endothelial nitric oxide synthase coupled activity and attenuates monocrotaline-induced pulmonary artery hypertension in rats.
Cardiomegaly
Mitochondrial biogenesis during pressure overload induced cardiac hypertrophy in adult rats.
Cardiomegaly
Myocyte-Derived Hsp90 Modulates Collagen Upregulation via Biphasic Activation of STAT-3 in Fibroblasts during Cardiac Hypertrophy.
Cardiomegaly
PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.
Cardiomegaly
Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy.
Cardiomegaly
Small heat shock protein 20 (HspB6) in cardiac hypertrophy and failure.
Cardiomegaly
Upregulation of autophagy genes and the unfolded protein response in human heart failure.
Cardiomegaly
[Exercise preconditioning attenuates pressure overload-induced pathological cardiac hypertrophy: potential role of HSF1 and NF-?B p65 signaling].
Cardiomegaly
[Progress in research on heat shock proteins in cardiovascular system]
Cardiomyopathies
?B-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments.
Cardiomyopathies
CaMKII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression.
Cardiomyopathies
Carnitine promotes heat shock protein synthesis in adriamycin-induced cardiomyopathy in a neonatal rat experimental model.
Cardiomyopathies
Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure.
Cardiomyopathies
Desmin-related cardiomyopathy in transgenic mice: a cardiac amyloidosis.
Cardiomyopathies
Direct and Indirect Involvement of MicroRNA-499 in Clinical and Experimental Cardiomyopathy.
Cardiomyopathies
Evaluation of the effect of heat shock protein 70 targeted drugs on cirrhotic cardiomyopathy in biliary cirrhotic rats.
Cardiomyopathies
Evidence for a functional role of the molecular chaperone clusterin in amyloidotic cardiomyopathy.
Cardiomyopathies
Global expression profiling identifies a novel biosignature for protein aggregation R120GCryAB cardiomyopathy in mice.
Cardiomyopathies
Heat shock protein 70 expression protects against sepsis-associated cardiomyopathy by inhibiting autophagy.
Cardiomyopathies
Heat stress in rat adriamycin cardiomyopathy: heat shock protein 25 and Myosin accumulation.
Cardiomyopathies
High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis.
Cardiomyopathies
Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy.
Cardiomyopathies
Increased expression of 78 kD glucose-regulated protein promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis.
Cardiomyopathies
Involvement of Reductive Stress in the Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Heat Shock Protein 27.
Cardiomyopathies
Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy.
Cardiomyopathies
Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules.
Cardiomyopathies
Phenotype of Cardiomyopathy in Cardiac-specific Heat Shock Protein B8 K141N Transgenic Mouse.
Cardiomyopathies
Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy.
Cardiomyopathies
Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy.
Cardiomyopathies
Proteomic analysis reveals significant elevation of heat shock protein 70 in patients with chronic heart failure due to arrhythmogenic right ventricular cardiomyopathy.
Cardiomyopathies
The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility.
Cardiomyopathies
The protective effect of heat shock protein 70 (Hsp70) in atrial fibrillation in various cardiomyopathy conditions.
Cardiomyopathy, Alcoholic
Atorvastatin reduces alcohol-induced endoplasmic reticulum stress in AC16 cardiomyocytes.
Cardiomyopathy, Dilated
A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.
Cardiomyopathy, Dilated
Antibodies against stress proteins in sera of patients with dilated cardiomyopathy.
Cardiomyopathy, Dilated
Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure.
Cardiomyopathy, Dilated
Dilated Cardiomyopathy (DCM)-linked Heat shock protein Family D Member 1 (HSPD1) mutations cause upregulation of ROS and autophagy through mitochondrial dysfunction.
Cardiomyopathy, Dilated
Heat shock protein 25-enriched plasma transfusion preconditions the heart against doxorubicin-induced dilated cardiomyopathy in mice.
Cardiomyopathy, Dilated
Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy.
Cardiomyopathy, Dilated
Molecular chaperone, HSP60, and cytochrome P450 2E1 co-expression in dilated cardiomyopathy.
Cardiomyopathy, Dilated
Refined purification of large amounts of Rat cvHsp/HspB7 and partial biological characterization in vitro.
Cardiomyopathy, Dilated
The expression of heat shock protein 60 in patients with dilated cardiomyopathy.
Cardiomyopathy, Dilated
[Effects of Mongolian new medicine-? on cardiac functions, endoplasmic reticulum stress and apoptosis in congestive heart failure rats with dilated cardiomyopathy].
Cardiomyopathy, Hypertrophic
Substantial decrease of heat shock protein 90 in ventricular tissues of two sudden-death pigs with hypertrophic cardiomyopathy.
Cardiotoxicity
Aptamer-Peptide Conjugates as Targeted Chemosensitizers for Breast Cancer Treatment.
Cardiotoxicity
Atrazine-xenobiotic nuclear receptor interactions induce cardiac inflammation and endoplasmic reticulum stress in quail (Coturnix coturnix coturnix).
Cardiotoxicity
CaMKII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression.
Cardiotoxicity
Cardiomyocyte Stim1 Deficiency Exacerbates Doxorubicin Cardiotoxicity by Magnification of Endoplasmic Reticulum Stress.
Cardiotoxicity
Doxorubicin-induced cardiotoxicity: direct correlation of cardiac fibroblast and H9c2 cell survival and aconitase activity with heat shock protein 27.
Cardiotoxicity
Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity.
Cardiotoxicity
Heat Shock Protein 22 Attenuates Doxorubicin-Induced Cardiotoxicity via Regulating Inflammation and Apoptosis.
Cardiotoxicity
Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway.
Cardiotoxicity
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Cardiotoxicity
Overexpression of Hsp20 prevents endotoxin-induced myocardial dysfunction and apoptosis via inhibition of NF-kappaB activation.
Cardiotoxicity
Pretreatment effect of running exercise on HSP70 and DOX-induced cardiotoxicity.
Cardiotoxicity
Rosuvastatin and simvastatin attenuate cisplatin-induced cardiotoxicity via disruption of endoplasmic reticulum stress-mediated apoptotic death in rats: targeting ER-Chaperone GRP78 and Calpain-1 pathways.
Cardiotoxicity
Short-term exercise training protects against doxorubicin-induced cardiac mitochondrial damage independent of HSP72.
Cardiotoxicity
Synthesis of shock proteins in cultured fetal mouse myocardial cells.
Cardiotoxicity
The hERG channel is dependent upon the Hsp90? isoform for maturation and trafficking.
Cardiovascular Diseases
32nd national medicinal chemistry symposium - medicinal chemistry developments for neurodegeneration, diabetes and cancer.
Cardiovascular Diseases
Antibodies against heat shock protein 60 derived from Helicobacter pylori: diagnostic implications in cardiovascular disease.
Cardiovascular Diseases
Antibodies against human 60 kDa heat shock protein are not associated with cardiovascular disease in patients with rheumatoid arthritis.
Cardiovascular Diseases
Antibodies to heat-shock protein 65 and neopterin levels in patients with type 1 diabetes mellitus.
Cardiovascular Diseases
Association between plasma levels of heat shock protein 60 and cardiovascular disease in patients with diabetes mellitus.
Cardiovascular Diseases
Autoimmunity, Infectious Immunity, and Atherosclerosis.
Cardiovascular Diseases
Cardiovascular disease delay in centenarian offspring: role of heat shock proteins.
Cardiovascular Diseases
Characterization of heat shock protein 27 in extracellular vesicles: a potential anti-inflammatory therapy.
Cardiovascular Diseases
Chlamydia pneumoniae, heat shock proteins 60 and risk of secondary cardiovascular events in patients with coronary heart disease under special consideration of diabetes : a prospective study.
Cardiovascular Diseases
Circulating heat shock protein 60 is associated with early cardiovascular disease.
Cardiovascular Diseases
Comparative analysis of linear antibody epitopes on human and mycobacterial 60-kDa heat shock proteins using samples of healthy blood donors.
Cardiovascular Diseases
Correlation between heat-shock protein 27 serum concentration and common carotid intima-media thickness in hemodialysis patients.
Cardiovascular Diseases
Diesel exhaust inhalation induces heat shock protein 70 expression in vivo.
Cardiovascular Diseases
Effect of crocin on antibody titers to heat-shock protein 27 in subjects with metabolic syndrome.
Cardiovascular Diseases
Heat shock protein 27 immune complex altered signaling and transport (ICAST): Novel mechanisms of attenuating inflammation.
Cardiovascular Diseases
Heat Shock Protein 60 in Cardiovascular Physiology and Diseases.
Cardiovascular Diseases
Heat shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway.
Cardiovascular Diseases
Heat shock proteins in cardiovascular disease and the prognostic value of heat shock protein related measurements.
Cardiovascular Diseases
Heat shock proteins in obesity: links to cardiovascular disease.
Cardiovascular Diseases
Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study.
Cardiovascular Diseases
Induction of Dendritic Cell-Mediated Activation of T Cells From Atherosclerotic Plaques by Human Heat Shock Protein 60.
Cardiovascular Diseases
Molecular chaperones: Toward new therapeutic tools.
Cardiovascular Diseases
Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules.
Cardiovascular Diseases
Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression.
Cardiovascular Diseases
Plasma concentration of heat shock protein 27 and risk of cardiovascular disease: a prospective, nested case-control study.
Cardiovascular Diseases
The left ventricle proteome differentiates middle-aged and old left ventricles in mice.
Cardiovascular Diseases
The potential role of heat shock protein 27 in cardiovascular disease.
Cardiovascular Diseases
The versatile stress protein mortalin as a chaperone therapeutic agent.
Cardiovascular Diseases
Unlike estrogens that increase PCSK9 levels post-menopause HSP27 vaccination lowers cholesterol levels and atherogenesis due to divergent effects on PCSK9 and LDLR.
Carotid Artery Diseases
Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk.
Carotid Artery Diseases
Autoantibodies against heat shock protein 60 mediate endothelial cytotoxicity.
Carotid Artery Diseases
Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis.
Carotid Artery Diseases
Heat shock proteins and autoimmunity in patients with carotid atherosclerosis.
Carotid Artery Diseases
Heat-shock protein 90: A novel autoantigen in human carotid atherosclerosis.
Carotid Artery Diseases
Oxidative Stress Induces HSP90 Upregulation on the Surface of Primary Human Endothelial Cells: Role of the Antioxidant 7,8-Dihydroxy-4-methylcoumarin in Preventing HSP90 Exposure to the Immune System.
Carotid Artery Diseases
Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study.
Carotid Artery Diseases
The role of (auto-) immunity in atherogenesis.
Carotid Artery Injuries
Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis.
Carotid Stenosis
1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.
Carotid Stenosis
A relationship between serological markers of chronic C. pneumoniae and CMV infection and hsp60 in patients with atherosclerotic carotid stenosis.
Carotid Stenosis
Increased expression of HDJ-2 (hsp40) in carotid artery atherosclerosis: a novel heat shock protein associated with luminal stenosis and plaque ulceration.
Carotid Stenosis
Involvement of -308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients.
Castleman Disease
Heat shock-enhanced T cell apoptosis with heat shock protein 70 on T cell surface in multicentric Castleman's disease.
Cat-Scratch Disease
Bartonella infections in fleas (Siphonaptera: Pulicidae) and lack of bartonellae in ticks (Acari: Ixodidae) from Hungary.
Cat-Scratch Disease
Evaluation of an internally controlled real-time polymerase chain reaction assay targeting the groEL gene for the detection of Bartonella spp. DNA in patients with suspected cat-scratch disease.
Cat-Scratch Disease
Rapid detection of Bartonella henselae heat shock protein DNA by nested polymerase chain reaction from swollen lymph nodes of a patient with cat-scratch disease.
Cataract
A possible relationship between cataract, increased levels of the major heat shock protein HSP 70 and decreased levels of S-antigen in the retina of the RCS rat.
Cataract
Administration of antioxidant compounds affects the lens chaperone activity and prevents the onset of cataracts.
Cataract
AlphaB-crystallin selectively targets intermediate filament proteins during thermal stress.
Cataract
Aqueous humor heat-shock protein 70, periostin, and irisin levels in patients with pseudoexfoliation syndrome.
Cataract
Association of partially folded lens betaB2-crystallins with the alpha-crystallin molecular chaperone.
Cataract
Calcium-induced decrease of the thermal stability and chaperone activity of alpha-crystallin.
Cataract
Chaperone-like activity and hydrophobicity of alpha-crystallin.
Cataract
Decreased chaperone activity of alpha-crystallins in naphthalene-induced cataract possibly results from C-terminal truncation.
Cataract
Differences in Unfolded Protein Response Pathway Activation in the Lenses of Three Types of Cataracts.
Cataract
Effect of trifluoroethanol on ?-crystallin: folding, aggregation, amyloid, and cytotoxicity analysis.
Cataract
Enhanced degradation and decreased stability of eye lens alpha-crystallin upon methylglyoxal modification.
Cataract
Genetic polymorphisms of HSP70 in age-related cataract.
Cataract
Glutathione reductase from human cataract lenses can be revived by reducing agents and by a molecular chaperone, alpha-crystallin.
Cataract
H101G Mutation in Rat Lens ?B-Crystallin Alters Chaperone Activity and Divalent Metal Ion Binding.
Cataract
Heat shock protein expression in human conjunctiva.
Cataract
Heat shock proteins of adult and embryonic human ocular lenses.
Cataract
Hydrophobic residues of melittin mediate its binding to ?A-crystallin.
Cataract
Identification of Differential Gene Expression Pattern in Lens Epithelial Cells Derived from Cataractous and Noncataractous Lenses of Shumiya Cataract Rat.
Cataract
Inactivation of glyceraldehyde 3-phosphate dehydrogenase by sugars, prednisolone-21-hemisuccinate, cyanate and other small molecules.
Cataract
Interaction of Cu+2 with ?-Crystallin: A Biophysical and Mass Spectrometric Study.
Cataract
Longitudinal Study of Age-Related Cataract Using Dynamic Light Scattering: Loss of ?-Crystallin Leads to Nuclear Cataract Development.
Cataract
Loss of ?B-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart.
Cataract
Oxidation of cysteine residues from alpha-A crystallin during cataractogenesis of the human lens.
Cataract
Structural and functional properties, chaperone activity and posttranslational modifications of alpha-crystallin and its related subunits in the crystalline lens: N-acetylcarnosine, carnosine and carcinine act as alpha- crystallin/small heat shock protein enhancers in prevention and dissolution of cataract in ocular drug delivery formulations of novel therapeutic agents.
Cataract
Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin.
Cataract
The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility.
Cataract
The impact of different water gas levels on cataract formation, muscle and lens free amino acids, and lens antioxidant enzymes and heat shock protein mRNA abundance in smolting Atlantic salmon, Salmo salar L.
Cataract
The lens of the eye as a focusing device and its response to stress.
Cataract
The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology.
Cataract
Thioredoxin, thioredoxin reductase, and alpha-crystallin revive inactivated glyceraldehyde 3-phosphate dehydrogenase in human aged and cataract lens extracts.
Cataract
Unfolded protein response activation in cataracts.
Cataract
Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation.
Cataract
UPR Activation and the Down-Regulation of ?-Crystallin in Human High Myopia-Related Cataract Lens Epithelium.
Cataract
Zn2+ enhances the molecular chaperone function and stability of alpha-crystallin.
Cataract
[Character of alpha-crystallin molecular chaperone activity in selenite cataract]
Cataract
[The molecular chaperone function of alpha-crystallin in age-related cataract]
Cataract
[The recent progress on the role of alpha-crystallin as a molecular chaperone in cataractogenesis]
Celiac Disease
AlphaB-crystallin expression in celiac disease - a preliminary study.
Celiac Disease
Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis.
Celiac Disease
HLA-linked heat-shock protein 70 (HSP70-2) gene polymorphism and celiac disease.
Celiac Disease
Increased heat shock protein 72 expression in celiac disease.
Central Nervous System Diseases
17-AAG post-treatment ameliorates memory impairment and hippocampal CA1 neuronal autophagic death induced by transient global cerebral ischemia.
Central Nervous System Diseases
Cloning, characterization, and functional studies of a human 40-kDa catecholamine-regulated protein: implications in central nervous system disorders.
Central Nervous System Diseases
Small heat shock proteins, the cytoskeleton, and inclusion body formation.
Central Nervous System Infections
[Significance of heat shock protein 70 in cerebrospinal fluid in differential diagnosis of central nervous system infection in children]
Cerebellar Diseases
GRP78 antibodies damage the blood-brain barrier and relate to cerebellar degeneration in Lambert-Eaton myasthenic syndrome.
Cerebral Amyloid Angiopathy
Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease.
Cerebral Hemorrhage
Deferoxamine affects heat shock protein expression in heart after intracerebral hemorrhage in aged rats.
Cerebral Hemorrhage
Effects of minocycline on the expression of NGF and HSP70 and its neuroprotection role following intracerebral hemorrhage in rats.
Cerebral Hemorrhage
Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage.
Cerebral Hemorrhage
Heme oxygenase-1 and heat shock protein 70 induction in glia and neurons throughout rat brain after experimental intracerebral hemorrhage.
Cerebral Hemorrhage
Increased Expression of Small Heat Shock Protein ?B-crystallin After Intracerebral Hemorrhage in Adult Rats.
Cerebral Hemorrhage
Inducible heat shock protein 70, interleukin-18, and tumor necrosis factor alpha correlate with outcomes in spontaneous intracerebral hemorrhage.
Cerebral Hemorrhage
Overexpression of GRP75 inhibits inflammation in a rat model of intracerebral hemorrhage.
Cerebral Hemorrhage
Pharmacological induction of heat shock protein exerts neuroprotective effects in experimental intracerebral hemorrhage.
Cerebral Infarction
Correlation of lymphocyte heat shock protein 70 levels with neurologic deficits in elderly patients with cerebral infarction.
Cerebral Infarction
Geranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in rats.
Cerebral Infarction
Heat shock protein 70 expression in the brain of rats with cerebral infarction after receiving vascular endothelial growth factor 165 gene therapy.
Cerebral Infarction
Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction.
Cerebral Infarction
Neuroprotective effect of geranylgeranylacetone, a noninvasive heat shock protein inducer, on cerebral infarction in rats.
Cerebral Infarction
Protective effects of Progranulin against focal cerebral ischemia-reperfusion injury in rats by suppressing endoplasmic reticulum stress and NF-?B activation in reactive astrocytes.
Cerebral Infarction
Protein Nanoparticles Modified with PDGF-B as a Novel Therapy After Acute Cerebral Infarction.
Cerebral Infarction
S100ß, Matrix Metalloproteinase-9, D-dimer, and Heat Shock Protein 70 Are Serologic Biomarkers of Acute Cerebral Infarction in a Mouse Model of Transient MCA Occlusion.
Cerebral Infarction
Semi-quantitative analyses of hippocampal heat shock protein-70 expression based on the duration of ischemia and the volume of cerebral infarction in mice.
Cerebral Infarction
The novel GLP-1/GIP dual agonist DA3-CH is more effective than liraglutide in reducing endoplasmic reticulum stress in diabetic rats with cerebral ischemia-reperfusion injury.
Cerebral Infarction
[Effects of Electroacupuncture and Intracerebral Injection of VEGF on Caspase12, Caspase3, and GRP78 Genes in Rats with Cerebral Ischemia-Reperfusion Injury].
Cerebral Infarction
[G protein-coupled estrogen receptor alleviates cerebral ischemia-reperfusion injury through inhibiting endoplasmic reticulum stress].
Cerebral Infarction
[Gene therapy for cerebral infarction (cerebral ischemia)]
Cerebral Infarction
[Study on plasma antibodies against heat shock protein 70 in the hypertensive patients with cerebral infarction]
Cerebrovascular Disorders
Heat Shock Protein 70 kDa as a Target for Diagnostics and Therapy of Cardiovascular and Cerebrovascular Diseases.
Cervical Intraepithelial Neoplasia
A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia.
Cervical Intraepithelial Neoplasia
Heat shock protein 27 and p16 immunohistochemistry in cervical intraepithelial neoplasia and squamous cell carcinoma.
Cervical Intraepithelial Neoplasia
Immunohistochemical evaluation of heat shock proteins in normal and preinvasive lesions of the cervix.
Cervical Intraepithelial Neoplasia
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.
Cervical Intraepithelial Neoplasia
Use of protein-based biomarkers of exfoliated cervical cells for primary screening of cervical cancer.
Chagas Disease
Gene expression and molecular modeling of the HSP104 chaperone of Trypanosoma cruzi.
Chagas Disease
Identification of HLA-A?02:01-restricted CTL epitopes in Trypanosoma cruzi heat shock protein-70 recognized by Chagas disease patients.
Chagas Disease
Multilocus PCR-RFLP profiling in Trypanosoma cruzi I highlights an intraspecific genetic variation pattern.
Chagas Disease
Recombinant Leishmania Hsp90 and Hsp70 are recognized by sera from visceral leishmaniasis patients but not Chagas' disease patients.
Chagas Disease
Trypanosoma cruzi: modulation of HSP70 mRNA stability by untranslated regions during heat shock.
Chancroid
Laboratory diagnosis of chancroid using species-specific primers from Haemophilus ducreyi groEL and the polymerase chain reaction.
Chancroid
The dnaK/dnaJ operon of Haemophilus ducreyi contains a unique combination of regulatory elements.
Charcot-Marie-Tooth Disease
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.
Charcot-Marie-Tooth Disease
A novel Lys141Thr mutation in small heat shock protein 22 (HSPB8) gene in Charcot-Marie-Tooth disease type 2L.
Charcot-Marie-Tooth Disease
A novel p.Glu175X premature stop mutation in the C-terminal end of HSP27 is a cause of CMT2.
Charcot-Marie-Tooth Disease
A novel p.T139M mutation in HSPB1 highlighting the phenotypic spectrum in a family.
Charcot-Marie-Tooth Disease
A novel transgenic mouse model of Chinese Charcot-Marie-Tooth disease type 2L.
Charcot-Marie-Tooth Disease
Abnormal small heat shock protein interactions involving neuropathy-associated HSP22 (HSPB8) mutants.
Charcot-Marie-Tooth Disease
Characterization of human small heat shock protein HSPB1 ?-crystallin domain localized mutants associated with hereditary motor neuron diseases.
Charcot-Marie-Tooth Disease
Distal hereditary motor neuropathy in Korean patients with a small heat shock protein 27 mutation.
Charcot-Marie-Tooth Disease
Heat shock protein 27 R127W mutation: evidence of a continuum between axonal Charcot-Marie-Tooth and distal hereditary motor neuropathy.
Charcot-Marie-Tooth Disease
Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy.
Charcot-Marie-Tooth Disease
Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27-induced Charcot Marie Tooth Disease.
Charcot-Marie-Tooth Disease
Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients.
Charcot-Marie-Tooth Disease
Mutation analysis of the small heat shock protein 27 gene in chinese patients with Charcot-Marie-Tooth disease.
Charcot-Marie-Tooth Disease
Small heat shock protein B3 (HSPB3) mutation in an axonal Charcot-Marie-Tooth disease family.
Charcot-Marie-Tooth Disease
The small heat shock protein HspB8: role in nervous system physiology and pathology.
Charcot-Marie-Tooth Disease
[Mutation analysis of small heat shock protein 27 gene in Chinese patients with Charcot-Marie-Tooth disease]
Charcot-Marie-Tooth Disease
[Study on aggregate formation mechanism of HSPB8 gene mutation resulting in CMT2L]
Chemical and Drug Induced Liver Injury
Analysis of IL-6, STAT3 and HSPA1L gene polymorphisms in anti-tuberculosis drug-induced hepatitis in a nested case-control study.
Chemical and Drug Induced Liver Injury
Biocharacterization of Heat Shock Protein 90 in Acetaminophen-Treated Livers Without Conspicuous Drug Induced Liver Injury.
Chemical and Drug Induced Liver Injury
Macrophage migration inhibitory factor in drug-induced liver injury: a role in susceptibility and stress responsiveness.
Chemical and Drug Induced Liver Injury
[Study on polymorphisms of genes with susceptibility to drug induced liver injury in a cohort receiving anti-tuberculosis treatment].
Chickenpox
Molecular mimicry between varicella, measles virus and Hsp60 in type 1 diabetes associated HLA-DR3/DR4 molecules.
Chlamydophila Infections
Chlamydia pneumoniae infection acts as an endothelial stressor with the potential to initiate the earliest heat shock protein 60-dependent inflammatory stage of atherosclerosis.
Chlamydophila Infections
Induction of oral tolerance as treatment or prevention of chronic diseases associated with Chlamydia pneumoniae infection--hypothesis.
Chlamydophila Infections
Serum immunoglobulin G antibodies to chlamydial heat shock protein 60 but not to human and bacterial homologs are associated with coronary artery disease.
Cholangiocarcinoma
Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma.
Cholangiocarcinoma
Characterization and prognostic significance of mortalin, Bcl-2 and Bax in intrahepatic cholangiocarcinoma.
Cholangiocarcinoma
Combined treatment of cholangiocarcinoma with interventional radiofrequency hyperthermia and heat shock protein promoter-mediated HSV-TK gene therapy.
Cholangiocarcinoma
Gene expression-based chemical genomics identifies heat-shock protein 90 inhibitors as potential therapeutic drugs in cholangiocarcinoma.
Cholangiocarcinoma
Glutamine Synthetase, Heat shock Protein-70, and Glypican-3 in Intrahepatic Cholangiocarcinoma and Tumors Metastatic to Liver.
Cholangiocarcinoma
Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.
Cholangiocarcinoma
Heat shock proteins 27 and 70 are potential biliary markers for the detection of cholangiocarcinoma.
Cholangiocarcinoma
Helicobacter pylori GroEL Seropositivity Is Associated with an Increased Risk of Opisthorchis viverrini-Associated Hepatobiliary Abnormalities and Cholangiocarcinoma.
Cholangiocarcinoma
HSP90 inhibition drives degradation of FGFR2 fusion proteins: implications for treatment of cholangiocarcinoma.
Cholangiocarcinoma
JNK contributes to the tumorigenic potential of human cholangiocarcinoma cells through the mTOR pathway regulated GRP78 induction.
Cholangiocarcinoma
MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma.
Cholangiocarcinoma
Mortalin promotes cell proliferation and epithelial mesenchymal transition of intrahepatic cholangiocarcinoma cells in vitro.
Cholangiocarcinoma
Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma.
Cholangiocarcinoma
Plasma autoantibodies against heat shock protein 70, enolase 1 and ribonuclease/angiogenin inhibitor 1 as potential biomarkers for cholangiocarcinoma.
Cholangiocarcinoma
TGR5 promotes cholangiocarcinoma by interacting with mortalin.
Cholangiocarcinoma
The heat shock protein 90 inhibitor 17-AAG suppresses growth and induces apoptosis in human cholangiocarcinoma cells.
Cholangitis, Sclerosing
Immuno-gold electron microscopical detection of heat shock protein 60 (hsp60) in mitochondria of rat hepatocytes and myocardiocytes.
Cholera
A novel design of a multi-antigenic, multistage and multi-epitope vaccine against Helicobacter pylori: An in silico approach.
Cholera
Co- and post-translocation roles for HSP90 in cholera Intoxication.
Cholera
Determination of the conformations of bound peptides using NMR-transferred nOe techniques.
Cholera
GRP75 upregulates clathrin-independent endocytosis through actin cytoskeleton reorganization mediated by the concurrent activation of Cdc42 and RhoA.
Cholera
Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.
Cholera
HSC70 and HSP90 chaperones perform complementary roles in translocation of the cholera toxin A1 subunit from the endoplasmic reticulum to the cytosol.
Cholera
Hsp90 is required for transfer of the cholera toxin A1 subunit from the endoplasmic reticulum to the cytosol.
Cholera
In vivo induced clpB1 gene of Vibrio cholerae is involved in different stress responses and affects in vivo cholera toxin production.
Cholera
Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery.
Cholestasis
Alpha-crystallin is a target gene of the farnesoid X-activated receptor in human livers.
Cholesteatoma
Heat shock proteins in middle ear cholesteatoma.
Cholesteatoma
TFIIB-related factor 2 regulates glucose-regulated protein 78 expression in acquired middle ear cholesteatoma.
Cholesteatoma
Upregulation of phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in acquired middle ear cholesteatoma growth.
Cholesteatoma, Middle Ear
TFIIB-related factor 2 regulates glucose-regulated protein 78 expression in acquired middle ear cholesteatoma.
Cholesteatoma, Middle Ear
Upregulation of phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in acquired middle ear cholesteatoma growth.
Chondroma
Heat shock protein 72 expression in chondrosarcoma correlates with differentiation.
Chondrosarcoma
Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas.
Chondrosarcoma
Distinct profiles of oxidative stress-related and matrix proteins in adult bone and soft tissue osteosarcoma and desmoid tumors: A proteomics study.
Chondrosarcoma
Heat shock protein 72 expression in chondrosarcoma correlates with differentiation.
Chondrosarcoma
HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma.
Chondrosarcoma
In Vitro and In Vivo Studies of the Biological Effects of Bioceramic (a Material of Emitting High Performance Far-Infrared Ray) Irradiation.
Chondrosarcoma
Recurrence rate and progression of chondrosarcoma is correlated with heat shock protein expression.
Chorioamnionitis
Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition.
Chorioamnionitis
Decreased expression of angiogenic factors in placentas with chorioamnionitis after preterm birth.
Choriocarcinoma
The heat shock protein 60 promotes progesterone synthesis in mitochondria of JEG-3 cells.
Chromoblastomycosis
Expression of heat shock protein 27 in chromomycosis.
Chronic Periodontitis
Association between circulating levels of heat-shock protein 27 and aggressive periodontitis.
Chronic Periodontitis
Evaluation of Salivary Level of Heat Shock Protein 70 in Patients with Chronic Periodontitis.
Chronic Periodontitis
Monitoring of dnaK gene expression in Porphyromonas gingivalis by oxygen stress using DNA microarray.
Chronic Periodontitis
Pep19 drives epitope spreading in periodontitis and periodontitis-associated autoimmune diseases.
Chronic Urticaria
Elevated circulating heat shock protein 70 and its antibody concentrations in chronic spontaneous urticaria.
Ciliary Motility Disorders
Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertility.
Classical Swine Fever
Molecular chaperone Jiv promotes the RNA replication of classical swine fever virus.
Cleft Palate
Gene expression of Hsp70, Hsp90 and Hsp110 families in normal palate and cleft palate during mouse embryogenesis.
Cleft Palate
P1 and cosmid clones define the organization of 280 kb of the mouse H-2 complex containing the Cps-1 and Hsp70 loci.
Cleft Palate
[Expression of sHsps of normal palate and cleft palate during mouse embryogenesis]
Clubfoot
EVEN-PLUS syndrome: A case report with novel variants in HSPA9 and evidence of HSPA9 gene dysfunction.
Coccidiosis
Eimeria tenella heat shock protein 70 enhances protection of recombinant microneme protein MIC2 subunit antigen vaccination against E. tenella challenge.
Coccidiosis
Heat shock protein 90 genes of two species of poultry Eimeria: expression and evolutionary analysis.
Coccidiosis
The heat shock protein 90 of Eimeria tenella is essential for invasion of host cell and schizont growth.
Coinfection
Anaplasma platys-like strains in ruminants from Tunisia.
Coinfection
Diversity of Anaplasma species and importance of mixed infections in roe deer from Spain.
Coinfection
Expression and purification of active receptor interacting protein 1 kinase using a baculovirus system.
Coinfection
First Report of Cucurbit Chlorotic Yellows Virus affecting Watermelon in USA.
Coinfection
Improvement of the production of GFPuv-beta1,3-N-acetylglucosaminyltransferase 2 fusion protein using a molecular chaperone-assisted insect-cell-based expression system.
Coinfection
Localization of sweet potato chlorotic stunt virus (SPCSV) in synergic infection with potyviruses in sweet potato.
Coinfection
Molecular Detection of Bartonella spp. and Hematological Evaluation in Domestic Cats and Dogs from Bangkok, Thailand.
Coinfection
Multiple Chlamydiaceae species in trachoma: implications for disease pathogenesis and control.
Coinfection
Serum levels of HSP70 and other DAMP proteins can aid in patient diagnosis after traumatic injury.
Coinfection
Subterranean Mammals: Reservoirs of Infection or Overlooked Sentinels of Anthropogenic Environmental Soiling?
Colic
Plasma levels of heat shock protein 72 (HSP72) and beta-endorphin as indicators of stress, pain and prognosis in horses with colic.
Colitis
A Humanized Monoclonal Antibody against Heat Shock Protein 60 Suppresses Murine Arthritis and Colitis and Skews the Cytokine Balance toward an Anti-Inflammatory Response.
Colitis
Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding.
Colitis
Activation of sirtuin 1 by catalpol-induced down-regulation of microRNA-132 attenuates endoplasmic reticulum stress in colitis.
Colitis
Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB.
Colitis
Daikenchuto, a kampo medicine, regulates intestinal fibrosis associated with decreasing expression of heat shock protein 47 and collagen content in a rat colitis model.
Colitis
Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats.
Colitis
Elongated Flexuous Plant Virus-Derived Nanoparticles Functionalized for Autoantibody Detection.
Colitis
Evaluation of ubiquitinated proteins by proteomics reveals the role of the ubiquitin proteasome system in the regulation of Grp75 and Grp78 chaperone proteins during intestinal inflammation.
Colitis
Exogenous heat shock protein gp96 ameliorates CD4+CD62L+ T-cell-mediated transfer colitis.
Colitis
Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis.
Colitis
Hyperthermia ameliorates 2,4,6-trinitrobenzene sulphonic acid-induced colitis in rats: the role of heat shock proteins.
Colitis
Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation.
Colitis
Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.
Colitis
Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function.
Colitis
Lactobacillus stress protein GroEL prevents colonic inflammation.
Colitis
Low and medium but not high doses of green tea polyphenols ameliorated dextran sodium sulfate-induced hepatotoxicity and nephrotoxicity.
Colitis
Mouse colitis induced by Escherichia coli producing Yersinia enterocolitica 60-kilodalton heat-shock protein: light and electron microscope study.
Colitis
Mucosal expression by B7-positive cells of the 60-kilodalton heat-shock protein in inflammatory bowel disease.
Colitis
Oral targeted delivery by nanoparticles enhances efficacy of an Hsp90 inhibitor by reducing systemic exposure in murine models of colitis and colitis-associated cancer.
Colitis
Resistance to experimental colitis depends on cytoprotective heat shock proteins in macrophage migration inhibitory factor null mice.
Colitis
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Colitis
Role of heat shock protein 47 in intestinal fibrosis of experimental colitis.
Colitis
Sex- and Corticotropin-releasing Factor Receptor 2- dependent Actions of Urocortin 1 during inflammation.
Colitis, Ischemic
Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding.
Colitis, Ulcerative
Autoimmunity to heat shock protein 40 in ulcerative colitis.
Colitis, Ulcerative
Changes in Immunohistochemical Levels and Subcellular Localization After Therapy and Correlation and Colocalization With CD68 Suggest a Pathogenetic Role of Hsp60 in Ulcerative Colitis.
Colitis, Ulcerative
Correlation between depression, anxiety, and polymorphonuclear cells' resilience in ulcerative colitis: the mediating role of heat shock protein 70.
Colitis, Ulcerative
Geranylgeranylacetone suppresses colitis?related mouse colon carcinogenesis.
Colitis, Ulcerative
Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation.
Colitis, Ulcerative
Heat shock protein gene 70-2 polymorphism is differentially associated with the clinical phenotypes of ulcerative colitis and Crohn's disease.
Colitis, Ulcerative
Heat-shock protein 70-2 BB genotype is associated with reduced risks of the steroid-dependent and refractory phenotypes of ulcerative colitis.
Colitis, Ulcerative
How autophagy controls the intestinal epithelial barrier.
Colitis, Ulcerative
Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy.
Colitis, Ulcerative
Hsp60 and Hsp10 increase in colon mucosa of Crohn's disease and ulcerative colitis.
Colitis, Ulcerative
Impaired humoral immune response against mycobacterial 65-kDa heat shock protein (HSP65) in patients with inflammatory bowel disease.
Colitis, Ulcerative
Increased Levels of Survivin, via Association With Heat Shock Protein 90, in Mucosal T Cells From Patients With Crohn's Disease.
Colitis, Ulcerative
Inflammatory Bowel Disease-Associated Interleukin-33 Is Preferentially Expressed in Ulceration-Associated Myofibroblasts.
Colitis, Ulcerative
Intestinal expression of human heat shock protein 90 in patients with Crohn's disease and ulcerative colitis.
Colitis, Ulcerative
Mucosal expression by B7-positive cells of the 60-kilodalton heat-shock protein in inflammatory bowel disease.
Colitis, Ulcerative
Oral targeted delivery by nanoparticles enhances efficacy of an Hsp90 inhibitor by reducing systemic exposure in murine models of colitis and colitis-associated cancer.
Colitis, Ulcerative
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Colitis, Ulcerative
Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer.
Colitis-Associated Neoplasms
Molecular regulation of macrophages in unleashing cancer-related inflammation.
Colitis-Associated Neoplasms
Oral targeted delivery by nanoparticles enhances efficacy of an Hsp90 inhibitor by reducing systemic exposure in murine models of colitis and colitis-associated cancer.
Colitis-Associated Neoplasms
Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer.
Colonic Neoplasms
17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines.
Colonic Neoplasms
90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
Colonic Neoplasms
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
Colonic Neoplasms
Acetylation modification regulates GRP78 secretion in colon cancer cells.
Colonic Neoplasms
Acquired resistance to 5-fluorouracil via HSP90/Src-mediated increase in thymidylate synthase expression in colon cancer.
Colonic Neoplasms
Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition.
Colonic Neoplasms
Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways.
Colonic Neoplasms
Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer.
Colonic Neoplasms
Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice.
Colonic Neoplasms
BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.
Colonic Neoplasms
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Colonic Neoplasms
Both Bupivacaine and Levobupivacaine inhibit colon cancer cell growth but not melanoma cells in vitro.
Colonic Neoplasms
Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
Colonic Neoplasms
Cell-bound exopolysaccharide from probiotic bacteria induces autophagic cell death of tumour cells.
Colonic Neoplasms
Co-crystalization and in vitro biological characterization of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole hsp90 inhibitors.
Colonic Neoplasms
Colon cancer cell treatment with rose bengal generates a protective immune response via immunogenic cell death.
Colonic Neoplasms
Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity.
Colonic Neoplasms
Cryptotanshinone-Induced p53-Dependent Sensitization of Colon Cancer Cells to Apoptotic Drive by Regulation of Calpain and Calcium Homeostasis.
Colonic Neoplasms
Curcumin Reverses 5-Fluorouracil Resistance by Promoting Human Colon Cancer HCT-8/5-FU Cell Apoptosis and Down-regulating Heat Shock Protein 27 and P-Glycoprotein.
Colonic Neoplasms
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer.
Colonic Neoplasms
Delivery of functional exogenous proteins by plant-derived vesicles to human cells in vitro.
Colonic Neoplasms
DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines.
Colonic Neoplasms
Downregulation of DNAJC10 (ERDJ5) is associated with poor survival in breast cancer.
Colonic Neoplasms
Effect of Root Extracts of Medicinal Herb Glycyrrhiza glabra on HSP90 Gene Expression and Apoptosis in the HT-29 Colon Cancer Cell Line.
Colonic Neoplasms
Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Colonic Neoplasms
Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Colonic Neoplasms
Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma.
Colonic Neoplasms
Expression of stress response protein glucose regulated protein-78 mediated by c-Myb.
Colonic Neoplasms
Expression profile of significant immortalization genes in colon cancer.
Colonic Neoplasms
Extracellular Hsp90 and TGF? regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model.
Colonic Neoplasms
Ganetespib, a novel Hsp90 inhibitor in patients with KRAS mutated and wild type, refractory metastatic colorectal cancer.
Colonic Neoplasms
Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells.
Colonic Neoplasms
Geldanamycin-Induced PCNA Degradation in Isolated Hsp90 Complex from Cancer Cells.
Colonic Neoplasms
Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.
Colonic Neoplasms
Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.
Colonic Neoplasms
Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway.
Colonic Neoplasms
Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells.
Colonic Neoplasms
Glucose-regulated protein 78 silencing down-regulates vascular endothelial growth factor/vascular endothelial growth factor receptor 2 pathway to suppress human colon cancer tumor growth.
Colonic Neoplasms
GRP-induced up-regulation of Hsp72 promotes CD16+/94+ natural killer cell binding to colon cancer cells causing tumor cell cytolysis.
Colonic Neoplasms
GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells.
Colonic Neoplasms
GRP78 mediates the therapeutic efficacy of curcumin on colon cancer.
Colonic Neoplasms
GRP78 Regulates Apoptosis, Cell Survival and Proliferation in 5-Fluorouracil-resistant SNUC5 Colon Cancer Cells.
Colonic Neoplasms
GRP78 secreted by colon cancer cells facilitates cell proliferation via PI3K/Akt signaling.
Colonic Neoplasms
Heat shock cognate protein 70 encodes antigenic epitopes recognised by HLA-B4601-restricted cytotoxic T lymphocytes from cancer patients.
Colonic Neoplasms
Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation.
Colonic Neoplasms
Heat shock protein 27 knockdown using nucleotide?based therapies enhances sensitivity to 5-FU chemotherapy in SW480 human colon cancer cells.
Colonic Neoplasms
Heat shock protein 27, a novel regulator of 5-fluorouracil resistance in colon cancer.
Colonic Neoplasms
Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Colonic Neoplasms
Heat Shock Protein 70s as Potential Molecular Targets for Colon Cancer Therapeutics.
Colonic Neoplasms
High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer.
Colonic Neoplasms
Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein.
Colonic Neoplasms
Hsp90 inhibitor sensitizes TRAIL-mediated apoptosis via chop-dependent DR5 upregulation in colon cancer cells.
Colonic Neoplasms
Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.
Colonic Neoplasms
Hsp90 inhibitors sensitise human colon cancer cells to topoisomerase I poisons by depletion of key anti-apoptotic and cell cycle checkpoint proteins.
Colonic Neoplasms
HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells.
Colonic Neoplasms
Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.
Colonic Neoplasms
Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.
Colonic Neoplasms
Hybrid Nanoparticles Modified by Hyaluronic Acid Loading an HSP90 Inhibitor as a Novel Delivery System for Subcutaneous and Orthotopic Colon Cancer Therapy.
Colonic Neoplasms
Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer.
Colonic Neoplasms
Identification of Tumor Antigen AF20 as Glycosylated Transferrin Receptor 1 in Complex with Heat Shock Protein 90 and/or Transporting ATPase.
Colonic Neoplasms
Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma.
Colonic Neoplasms
Increased sensitivity of human colon cancer cells to DNA cross-linking agents after GRP78 up-regulation.
Colonic Neoplasms
Indirect participation of Hsp90 in the regulation of the cyclin E turnover.
Colonic Neoplasms
Inducible heat shock protein 70 prevents multifocal flat dysplastic lesions and invasive tumors in an inflammatory model of colon cancer.
Colonic Neoplasms
Induction of HSF1 expression is associated with sporadic colorectal cancer.
Colonic Neoplasms
Induction of Hsp60 by Photofrin-mediated photodynamic therapy.
Colonic Neoplasms
Inhibition of Heat Shock Protein 90 as a Novel Platform for the Treatment of Cancer.
Colonic Neoplasms
Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress.
Colonic Neoplasms
Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol.
Colonic Neoplasms
Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer.
Colonic Neoplasms
Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.
Colonic Neoplasms
Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability.
Colonic Neoplasms
N-myristoyltransferase inhibitor protein is homologous to heat shock cognate protein 70.
Colonic Neoplasms
Novel immunohistochemical monoclonal antibody against human glucose-regulated protein 78.
Colonic Neoplasms
Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-?/Smad2/3 signaling.
Colonic Neoplasms
Overexpression of glucose-regulated protein 78 in colon cancer.
Colonic Neoplasms
Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives.
Colonic Neoplasms
p53 Regulates Hsp90 ATPase Activity and Thereby Wnt Signaling by Modulating Aha1 Expression.
Colonic Neoplasms
PADI3 plays an antitumor role via the Hsp90/CKS1 pathway in colon cancer.
Colonic Neoplasms
Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis.
Colonic Neoplasms
Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer.
Colonic Neoplasms
Polymer mediated transport of the Hsp90 inhibitor LB76, a polar cyclic peptide, produces an Hsp90 cellular phenotype.
Colonic Neoplasms
Prediagnostic Helicobacter pylori Antibodies and Colorectal Cancer Risk in an Elderly, Caucasian Population.
Colonic Neoplasms
Proteasome inhibition potentiates the cytotoxic effects of hyperthermia in HT-29 colon cancer cells through inhibition of heat shock protein 27.
Colonic Neoplasms
Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer.
Colonic Neoplasms
Quantitative effects on c-Jun N-terminal protein kinase signaling determine synergistic interaction of cisplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines.
Colonic Neoplasms
Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.
Colonic Neoplasms
Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation.
Colonic Neoplasms
Role of apoptosis in colon cancer biology, therapy, and prevention.
Colonic Neoplasms
Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.
Colonic Neoplasms
ShRNA-mediated gene silencing of Heat shock protein 70 inhibits human colon cancer cell growth in vitro and in vivo.
Colonic Neoplasms
ShRNA-mediated gene silencing of heat shock protein 70 inhibits human colon cancer growth.
Colonic Neoplasms
Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors.
Colonic Neoplasms
Suppression of heat shock protein 27 expression promotes 5-fluorouracil sensitivity in colon cancer cells in a xenograft model.
Colonic Neoplasms
Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells.
Colonic Neoplasms
Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studies.
Colonic Neoplasms
The interplay between GRP78 expression and Akt activation in human colon cancer cells under celecoxib treatment.
Colonic Neoplasms
The molecular chaperone Cosmc enhances malignant behaviors of colon cancer cells via activation of Akt and ERK.
Colonic Neoplasms
Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23.
Colonic Neoplasms
Upregulated Heat Shock Proteins After Hyperthermic Chemotherapy Point to Induced Cell Survival Mechanisms in Affected Tumor Cells From Peritoneal Carcinomatosis.
Colorectal Neoplasms
(-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-?B/miR-155-5p/MDR1 Pathway.
Colorectal Neoplasms
A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer.
Colorectal Neoplasms
Anti-cancer effects of chemotherapeutic agent; 17-AAG, in combined with gold nanoparticles and irradiation in human colorectal cancer cells.
Colorectal Neoplasms
Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1? and STAT-3.
Colorectal Neoplasms
ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells.
Colorectal Neoplasms
ATAD3A stabilizes GRP78 to suppress ER stress for acquired chemoresistance in colorectal cancer.
Colorectal Neoplasms
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Colorectal Neoplasms
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Colorectal Neoplasms
Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion.
Colorectal Neoplasms
Cetuximab promotes SN38 sensitivity via suppression of heat shock protein 27 in colorectal cancer cells with wild-type RAS.
Colorectal Neoplasms
CFTR interacts with Hsp90 and regulates the phosphorylation of AKT and ERK1/2 in colorectal cancer cells.
Colorectal Neoplasms
Circulating mitochondrial stress 70 protein/mortalin and cytosolic Hsp70 in blood: Risk indicators in colorectal cancer.
Colorectal Neoplasms
Clinicopathologic significance of TRAP1 expression in colorectal cancer: a large scale study of human colorectal adenocarcinoma tissues.
Colorectal Neoplasms
Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity.
Colorectal Neoplasms
Combination of TRAP1 and ERCC1 Expression Predicts Clinical Outcomes in Metastatic Colorectal Cancer Treated with Oxaliplatin/5-Fluorouracil.
Colorectal Neoplasms
Combination therapies with HSP90 inhibitors against colorectal cancer.
Colorectal Neoplasms
Combining Trail with PI3 Kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.
Colorectal Neoplasms
Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?
Colorectal Neoplasms
Decreased expression of heat shock protein 20 in colorectal cancer and its implication in tumorigenesis.
Colorectal Neoplasms
Diagnostic, clinicopathologic, therapeutic and prognostic value of Plasma Heat Shock Protein 90 levels in patients with advanced Gastrointestinal Carcinoma.
Colorectal Neoplasms
Differential expression of HSP90 isoforms and their correlations with clinicopathologic factors in patients with colorectal cancer.
Colorectal Neoplasms
Differential proteomic analysis of human colorectal carcinoma cell lines metastasis-associated proteins.
Colorectal Neoplasms
Dihydropyrimidine Dehydrogenase Levels in Colorectal Cancer Cells Treated with a Combination of Heat Shock Protein 90 Inhibitor and Oxaliplatin or Capecitabine.
Colorectal Neoplasms
Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer.
Colorectal Neoplasms
Dominant high expression of wild-type HSP110 defines a poor prognostic subgroup of colorectal carcinomas with microsatellite instability: a whole-section immunohistochemical analysis.
Colorectal Neoplasms
Elevated levels of mitochondrial mortalin and cytosolic HSP70 in blood as risk factors in patients with colorectal cancer.
Colorectal Neoplasms
Exploiting the HSP60/10 chaperonin system as a chemotherapeutic target for colorectal cancer.
Colorectal Neoplasms
Expression of heat shock protein (Hsp) 70 and Hsp 40 in colorectal cancer.
Colorectal Neoplasms
FBW7-Dependent Mcl-1 Degradation Mediates the Anticancer Effect of Hsp90 Inhibitors.
Colorectal Neoplasms
Ganetespib, a novel Hsp90 inhibitor in patients with KRAS mutated and wild type, refractory metastatic colorectal cancer.
Colorectal Neoplasms
Gene Copy Number and Post-Transductional Mechanisms Regulate TRAP1 Expression in Human Colorectal Carcinomas.
Colorectal Neoplasms
Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis.
Colorectal Neoplasms
Glucose-regulated protein 78 contributes to the proliferation and tumorigenesis of human colorectal carcinoma via AKT and ERK pathways.
Colorectal Neoplasms
GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the ?-catenin signaling.
Colorectal Neoplasms
GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Colorectal Neoplasms
GRP78 regulates sensitivity of human colorectal cancer cells to DNA targeting agents.
Colorectal Neoplasms
Heat shock protein 105 peptide vaccine could induce antitumor immune reactions in a phase I clinical trial.
Colorectal Neoplasms
Heat shock protein 27 is associated with irinotecan resistance in human colorectal cancer cells.
Colorectal Neoplasms
Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer.
Colorectal Neoplasms
Heat shock protein 70 and HLA-DR molecules tissue expression. Prognostic implications in colorectal cancer.
Colorectal Neoplasms
Heat shock protein 70 is a useful marker for predicting colorectal cancer.
Colorectal Neoplasms
Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth.
Colorectal Neoplasms
Heat Shock Protein 70s as Potential Molecular Targets for Colon Cancer Therapeutics.
Colorectal Neoplasms
Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability.
Colorectal Neoplasms
Heat shock protein 90 is involved in the regulation of HMGA2-driven growth and epithelial-to-mesenchymal transition of colorectal cancer cells.
Colorectal Neoplasms
Heat shock protein 90 promotes epithelial to mesenchymal transition, invasion, and migration in colorectal cancer.
Colorectal Neoplasms
Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.
Colorectal Neoplasms
High clusterin (CLU) mRNA expression levels in tumors of colorectal cancer patients predict a poor prognostic outcome.
Colorectal Neoplasms
High expression of HSP90 is associated with poor prognosis in patients with colorectal cancer.
Colorectal Neoplasms
How autophagy controls the intestinal epithelial barrier.
Colorectal Neoplasms
HSP60, a protein downregulated by IGFBP7 in colorectal carcinoma.
Colorectal Neoplasms
Hsp60: molecular anatomy and role in colorectal cancer diagnosis and treatment.
Colorectal Neoplasms
Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Colorectal Neoplasms
HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy.
Colorectal Neoplasms
HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells.
Colorectal Neoplasms
HSP90 inhibitor enhances anti-proliferative and apoptotic effects of celecoxib on HT-29 colorectal cancer cells via increasing BAX/BCL-2 ratio.
Colorectal Neoplasms
HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells.
Colorectal Neoplasms
Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library.
Colorectal Neoplasms
Identification of heat shock protein 90? as an IMH-2 epitope-associated protein and correlation of its mRNA overexpression with colorectal cancer metastasis and poor prognosis.
Colorectal Neoplasms
Identification of the circRNA-miRNA-mRNA regulatory network of Hsp90 inhibitor-induced cell death in colorectal cancer by integrated analysis.
Colorectal Neoplasms
Immunohistochemical detection of HSP27 and hnRNP K as prognostic and predictive biomarkers for colorectal cancer.
Colorectal Neoplasms
Increased Temperature Facilitates Adeno-Associated Virus Vector Transduction of Colorectal Cancer Cell Lines in a Manner Dependent on Heat Shock Protein Signature.
Colorectal Neoplasms
Induced oxidative stress and decreased expression of inducible heat shock protein 70 (ihsp 70) in patients with colorectal adenocarcinomas.
Colorectal Neoplasms
Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines.
Colorectal Neoplasms
Inhibition of heat shock protein 27 phosphorylation promotes sensitivity to 5-fluorouracil in colorectal cancer cells.
Colorectal Neoplasms
Inhibition of MEK sensitizes paclitaxel-induced apoptosis of human colorectal cancer cells by downregulation of GRP78.
Colorectal Neoplasms
Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
Colorectal Neoplasms
Knockdown of CEMIP suppresses proliferation and induces apoptosis in colorectal cancer cells: downregulation of GRP78 and attenuation of unfolded protein response.
Colorectal Neoplasms
Lipoproteins LDL versus HDL as nanocarriers to target either cancer cells or macrophages.
Colorectal Neoplasms
Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer.
Colorectal Neoplasms
Mitochondrial chaperone Trap1 and the calcium binding protein Sorcin interact and protect cells against apoptosis induced by antiblastic agents.
Colorectal Neoplasms
Molecular characterization of hsp90 isoforms in colorectal cancer cells and its association with tumour progression.
Colorectal Neoplasms
Mortalin contributes to colorectal cancer by promoting proliferation and epithelial-mesenchymal transition.
Colorectal Neoplasms
Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival.
Colorectal Neoplasms
Multi-panel assay of serum autoantibodies in colorectal cancer.
Colorectal Neoplasms
Nanofitins targeting heat shock protein 110: An innovative immunotherapeutic modality in cancer.
Colorectal Neoplasms
Natural killer and NK-Like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96.
Colorectal Neoplasms
Novel serum markers HSP60, CHI3L1, and IGFBP-2 in metastatic colorectal cancer.
Colorectal Neoplasms
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Colorectal Neoplasms
Overexpression of the mitochondrial chaperone tumor necrosis factor receptor-associated protein 1 is associated with the poor prognosis of patients with colorectal cancer.
Colorectal Neoplasms
P53 and heat shock protein 70 expressions in colorectal adenocarcinoma.
Colorectal Neoplasms
Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracilbased chemotherapy.
Colorectal Neoplasms
Plasma Levels of Heat Shock Protein 90 Alpha Associated With Colorectal Cancer Development.
Colorectal Neoplasms
Polymorphisms of glucose-regulated protein 78 and risk of colorectal cancer: a case-control study in southwest china.
Colorectal Neoplasms
Prediagnostic Helicobacter pylori Antibodies and Colorectal Cancer Risk in an Elderly, Caucasian Population.
Colorectal Neoplasms
Preoperative heat shock protein 47 levels identify colorectal cancer patients with lymph node metastasis and poor prognosis.
Colorectal Neoplasms
Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90.
Colorectal Neoplasms
Prognostic significance of glucose-related protein 94 in colorectal cancer.
Colorectal Neoplasms
Proteomic analysis of Tiam1-mediated metastasis in colorectal cancer.
Colorectal Neoplasms
Proteomics analysis of differential protein expression identifies heat shock protein 47 as a predictive marker for lymph node metastasis in patients with colorectal cancer.
Colorectal Neoplasms
Proteomics-based identification of HSP60 as a tumor-associated antigen in colorectal cancer.
Colorectal Neoplasms
Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
Colorectal Neoplasms
Radiolabeled F(ab')2-cetuximab for theranostic purposes in colorectal and skin tumor-bearing mice models.
Colorectal Neoplasms
Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer.
Colorectal Neoplasms
Regulation of N-myristoyltransferase by novel inhibitor proteins.
Colorectal Neoplasms
Relationship between 18F-FDG uptake and heat shock protein 90? expression in colorectal cancer.
Colorectal Neoplasms
Role of Pluronic block copolymers in modulation of heat shock protein 70 expression.
Colorectal Neoplasms
Secreted Heat Shock Protein 90? (HSP90?) Induces Nuclear Factor-?B-mediated TCF12 Protein Expression to Down-regulate E-cadherin and to Enhance Colorectal Cancer Cell Migration and Invasion.
Colorectal Neoplasms
Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.
Colorectal Neoplasms
Serum heat shock protein 90? have an advantage in diagnosis of colorectal cancer at early stage.
Colorectal Neoplasms
Serum level of soluble 70-kD heat shock protein is associated with high mortality in patients with colorectal cancer without distant metastasis.
Colorectal Neoplasms
Silencing Heat Shock Protein 27 Inhibits the Progression and Metastasis of Colorectal Cancer (CRC) by Maintaining the Stability of Stromal Interaction Molecule 1 (STIM1) Proteins.
Colorectal Neoplasms
Suppression of GRP78 sensitizes human colorectal cancer cells to oxaliplatin by downregulation of CD24.
Colorectal Neoplasms
Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer.
Colorectal Neoplasms
The 8.1 ancestral MHC haplotype is strongly associated with colorectal cancer risk.
Colorectal Neoplasms
The Association Between HSP90/topoisomerase I Immunophenotype and the Clinical Features of Colorectal Cancers in Respect to KRAS Gene Status.
Colorectal Neoplasms
The Clinical Value of HSP60 in Digestive System Cancers: a Systematic Review and Meta-Analysis.
Colorectal Neoplasms
The Cytotoxicity of Kahweol in HT-29 Human Colorectal Cancer Cells Is Mediated by Apoptosis and Suppression of Heat Shock Protein 70 Expression.
Colorectal Neoplasms
The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer.
Colorectal Neoplasms
The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2? and IRE1?/XBP-1 in colorectal cancer.
Colorectal Neoplasms
The unfolded protein response regulator GRP78 is a novel predictive biomarker in colorectal cancer.
Colorectal Neoplasms
TLR4 is essential for dendritic cell activation and anti-tumor T-cell response enhancement by DAMPs released from chemically stressed cancer cells.
Colorectal Neoplasms
TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas.
Colorectal Neoplasms
TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma.
Colorectal Neoplasms
TRAP1 Regulates Wnt/?-Catenin Pathway through LRP5/6 Receptors Expression Modulation.
Colorectal Neoplasms
TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells.
Colorectal Neoplasms
UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.
Colorectal Neoplasms
Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer.
Colorectal Neoplasms
USP22-dependent HSP90AB1 expression promotes resistance to HSP90 inhibition in mammary and colorectal cancer.
Colorectal Neoplasms
Vacuolar Membrane ATPase Activity 21 Predicts a Favorable Outcome and Acts as a Suppressor in Colorectal Cancer.
Colorectal Neoplasms
[Association between expressions of HSP70, HSP90 and efficacy of chemotherapy in colorectal cancer patients with unresectable liver metastasis]
Colorectal Neoplasms
[Closely relationship between expression of endoplasmic reticulum molecular chaperone Grp94 and c-myc oncogene in human colorectal carcinoma cell lines]
Colorectal Neoplasms
[Co-inhibition effect of 17-DMAG and oxaliplatin on proliferation and invasion of colorectal cancer cells].
Colorectal Neoplasms
[Differential expression of secretagogin and glucose-related protein 78 in colorectal carcinoma: a proteome study]
Colorectal Neoplasms
[Expression and clinical significance of 14-3-3 sigma and heat shock protein 27 in colorectal cancer]
Colorectal Neoplasms
[Expression of HSP27 in colorectal carcinoma and its relationship with lymphatic metastasis.]
Colorectal Neoplasms
[Expression of P53 and heat shock protein in colorectal tumors: an immunohistochemical study]
Colorectal Neoplasms
[Expressions of heat shock protein (HSP) family HSP 60, 70 and 90alpha in colorectal cancer tissues and their correlations to pathohistological characteristics.]
Colorectal Neoplasms
[Roles of glucose-regulated protein 78 in proliferation and migration of human colorectal carcinoma cell line RKO].
Coma
Mitochondrial heat shock protein 60 is increased in cerebrospinal fluid following pediatric traumatic brain injury.
Coma
Neuron-Specific Enolase, S100 Calcium-Binding Protein B, and Heat Shock Protein 70 Levels in Patients With Intracranial Hemorrhage.
Coma
Survival rate and expression of Heat-shock protein 70 and Frost genes after temperature stress in Drosophila melanogaster lines that are selected for recovery time from temperature coma.
Coma
The combination of exercise training and alpha-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer's disease in NSE/APPsw-transgenic mice.
Communicable Diseases
A non-receptor-mediated mechanism for internalization of molecular chaperones.
Communicable Diseases
Binding of antigenic peptide to the endoplasmic reticulum-resident protein gp96/GRP94 heat shock chaperone occurs in higher order complexes. Essential role of some aromatic amino acid residues in the peptide-binding site.
Communicable Diseases
Design and synthesis of Grp94 selective inhibitors based on Phe199 induced fit mechanism and their anti-inflammatory effects.
Communicable Diseases
Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis.
Communicable Diseases
Functional role of Hsp60 as a positive regulator of human viral infection progression.
Communicable Diseases
Functions of the Hsp90 chaperone system: lifting client proteins to new heights.
Communicable Diseases
Hansenula polymorpha expressed heat shock protein gp96 exerts potent T cell activation activity as an adjuvant.
Communicable Diseases
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.
Communicable Diseases
Heat shock protein 90 from neglected protozoan parasites.
Communicable Diseases
Heat Shock Protein 90 Inhibitors as Broad Spectrum Anti-infectives.
Communicable Diseases
Heat-shock protein 70 gene sequencing for Leishmania species typing in European tropical infectious disease clinics.
Communicable Diseases
Homogeneous Escherichia coli chaperonin 60 induces IL-1 beta and IL-6 gene expression in human monocytes by a mechanism independent of protein conformation.
Communicable Diseases
Hsp100 Molecular Chaperone ClpB and Its Role in Virulence of Bacterial Pathogens.
Communicable Diseases
HSP60: issues and insights on its therapeutic use as an immunoregulatory agent.
Communicable Diseases
Hsp90 orchestrates temperature-dependent candida albicans morphogenesis via Ras1-PKA signaling.
Communicable Diseases
Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response.
Communicable Diseases
Mechanism and Complex Roles of HSC70 in Viral Infections.
Communicable Diseases
Plasma membrane expression of heat shock protein 60 in vivo in response to infection.
Communicable Diseases
Polymorphism in heat-shock protein 70-1 (HSP70-1) gene promoter region and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians.
Communicable Diseases
Relationships between the onset of pustulosis palmaris et plantaris, periodontitis and bacterial heat shock proteins.
Communicable Diseases
Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases.
Communicable Diseases
Significance of serum antibodies against HSP 60 and HSP 70 for the diagnostic of infectious diseases.
Communicable Diseases
Targeting Heat Shock Protein 90 for Malaria.
Communicable Diseases
TAT-mediated gp96 transduction to APCs enhances gp96-induced antiviral and antitumor T cell responses.
Communicable Diseases
The common heat shock protein receptor CD91 is up-regulated on monocytes of advanced melanoma slow progressors.
Communicable Diseases
The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype.
Communicable Diseases
The regulatory mechanism of Hsp90alpha secretion from endothelial cells and its role in angiogenesis during wound healing.
Communicable Diseases
The universe of Hsp90.
Communicable Diseases
[Role of heat shock protein-peptide complexes on tumor and infectious diseases immunity]
Confusion
Guidelines for the nomenclature of the human heat shock proteins.
Congenital Abnormalities
Characterization of heat shock protein 40 and 90 in Chironomus riparius larvae: effects of di(2-ethylhexyl) phthalate exposure on gene expressions and mouthpart deformities.
Congenital Abnormalities
Hsp90 and complex birth defects: A plausible mechanism for the interaction of genes and environment.
Congenital Abnormalities
Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia.
Congenital Abnormalities
Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells.
Congenital Hypothyroidism
DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components.
Conjunctivitis, Inclusion
Systemic immunization with Hsp60 alters the development of chlamydial ocular disease.
Contracture
Auxiliary proteins that facilitate formation of collagen-rich deposits in the posterior knee capsule in a rabbit-based joint contracture model.
Corneal Dystrophies, Hereditary
A novel proteotoxic stress associated mechanism for macular corneal dystrophy.
Corneal Opacity
The relationship between rabbit corneal opacity and immunohistochemical expression of heat shock protein 72/73 and c-fos after excimer laser photorefractive keratectomy.
Coronary Artery Disease
A cross-sectional study of the association between heat shock protein 27 antibody titers, pro-oxidant-antioxidant balance and metabolic syndrome in patients with angiographically-defined coronary artery disease.
Coronary Artery Disease
Acute Chlamydia pneumoniae infection with heat-shock-protein-60-related response in patients with acute coronary syndrome.
Coronary Artery Disease
An Aggregate Biomarker Risk Score Predicts High Risk of Near-Term Myocardial Infarction and Death: Findings From BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes).
Coronary Artery Disease
Anti-Heat Shock Protein 27 Titers and Oxidative Stress Levels are Elevated in Patients With Valvular Heart Disease.
Coronary Artery Disease
Antibodies against the human heat shock protein hsp70 in patients with severe coronary artery disease.
Coronary Artery Disease
Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease: evidence for an autoimmune component of atherogenesis.
Coronary Artery Disease
Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk.
Coronary Artery Disease
Association of heat shock protein polymorphisms with patient susceptibility to coronary artery disease comorbid depression and anxiety in a Chinese population.
Coronary Artery Disease
Association of heat shock protein70-2 (HSP70-2) gene polymorphism with coronary artery disease in an Iranian population.
Coronary Artery Disease
Chronic Infections and Atherosclerosis.
Coronary Artery Disease
Heat-shock protein 60 and cardiovascular disease: a paradoxical role.
Coronary Artery Disease
Hormone replacement therapy increases levels of antibodies against heat shock protein 65 and certain species of oxidized low density lipoprotein.
Coronary Artery Disease
Hsp70-2 gene polymorphism: susceptibility implication in Tunisian patients with coronary artery disease.
Coronary Artery Disease
Implications of antibodies to heat-shock proteins in ischemic heart disease.
Coronary Artery Disease
Increased serum levels of heat shock protein 70 are associated with low risk of coronary artery disease.
Coronary Artery Disease
Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis.
Coronary Artery Disease
Inverse association of ApoB and HSP60 antibodies with coronary artery disease in Indian population.
Coronary Artery Disease
Involvement of -308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients.
Coronary Artery Disease
Plasma heat shock protein 27 is associated with coronary artery disease, abdominal aortic aneurysm and peripheral artery disease.
Coronary Artery Disease
Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors.
Coronary Artery Disease
Prevalence of intimal heat shock protein 60 homologues in unstable angina and correlation with anti-heat shock protein antibody titers.
Coronary Artery Disease
Serum antibody titers against heat shock protein 27 are associated with the severity of coronary artery disease.
Coronary Artery Disease
Serum immunoglobulin G antibodies to chlamydial heat shock protein 60 but not to human and bacterial homologs are associated with coronary artery disease.
Coronary Artery Disease
Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infection.
Coronary Artery Disease
[Chlamydial and human heat shock protein 60 homologues in acute coronary syndromes. (Auto-)immune reactions as a link between infection and atherosclerosis]
Coronary Disease
Analysis of the association of a heat shock protein70-1 gene promoter polymorphism with myocardial infarction and coronary risk traits.
Coronary Disease
Antibodies against human heat-shock protein (hsp) 60 and mycobacterial hsp65 differ in their antigen specificity and complement-activating ability.
Coronary Disease
Antibodies to 60-kilodalton heat shock protein and outer membrane protein 2 of Chlamydia pneumoniae in patients with coronary heart disease.
Coronary Disease
Antibody response to chlamydial heat shock protein 60 is strongly associated with acute coronary syndromes.
Coronary Disease
Association between plasma levels of heat shock protein 60 and cardiovascular disease in patients with diabetes mellitus.
Coronary Disease
Autoantibodies to a specific peptide epitope of human Hsp60 (ATVLA) with homology to Helicobacter pylori HspB in H. pylori-infected patients.
Coronary Disease
Chlamydia pneumoniae, heat shock proteins 60 and risk of secondary cardiovascular events in patients with coronary heart disease under special consideration of diabetes : a prospective study.
Coronary Disease
Comparative study on antibodies to human and bacterial 60 kDa heat shock proteins in a large cohort of patients with coronary heart disease and healthy subjects.
Coronary Disease
Complement activating antibodies against the human 60 kDa heat shock protein as a new independent family risk factor of coronary heart disease.
Coronary Disease
Expression of heat shock proteins and nitrotyrosine in small arteries from patients with coronary heart disease.
Coronary Disease
Genetic variation in heat shock protein 60 gene and coronary heart disease in China: tagging-SNP haplotype analysis in a case-control study.
Coronary Disease
Genetic variations in HSPA8 gene associated with coronary heart disease risk in a Chinese population.
Coronary Disease
The relationship between carotid stiffness and circulating levels of heat shock protein 60 in middle-aged men and women.
Coronary Occlusion
Attenuation of heat shock protein expression by coronary occlusion in hypertrophied hearts.
Coronary Occlusion
Differential stress protein mRNA expression during early ischaemic preconditioning in the rabbit heart and its relationship to adenosine receptor function.
Coronary Occlusion
Identification of a NF-?B cardioprotective gene program: NF-?B regulation of Hsp70.1 contributes to cardioprotection after permanent coronary occlusion.
Coronary Occlusion
Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning.
Coronavirus Infections
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells.
Coronavirus Infections
The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection.
Corticobasal Degeneration
The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration.
COVID-19
A connectivity map-based drug repurposing study and integrative analysis of transcriptomic profiling of SARS-CoV-2 infection.
COVID-19
A possible role for GRP78 in cross vaccination against COVID-19.
COVID-19
Are Hsp90 inhibitors good candidates against Covid-19?
COVID-19
Cancer progression in COVID-19: integrating the roles of renin angiotensin aldosterone system, angiopoietin-2, heat shock protein-27 and epithelial mesenchymal transition.
COVID-19
COVID-19 and hypertension: is the HSP60 culprit for the severe course and worse outcome?
COVID-19
COVID-19 spike-host cell receptor GRP78 binding site prediction.
COVID-19
Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention.
COVID-19
COVID-19: Is There a Link between Alcohol Abuse and SARS-CoV-2-Induced Severe Neurological Manifestations?
COVID-19
COVID19 associated mucormycosis: Is GRP78 a possible link?
COVID-19
Does the compromised sleep and circadian disruption of night and shiftworkers make them highly vulnerable to 2019 coronavirus disease (COVID-19)?
COVID-19
Endoplasmic Reticulum Stress Markers in SARS-COV-2 Infection and Pneumonia: Case-Control Study.
COVID-19
Evaluation of vertical transmission of SARS-CoV-2 in utero: Nine pregnant women and their newborns.
COVID-19
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.
COVID-19
High GRP78 levels in Covid-19 infection: A case-control study.
COVID-19
Hsp90 inhibition protects the brain microvascular endothelium against oxidative stress.
COVID-19
Inflammation Profiling of Critically Ill Coronavirus Disease 2019 Patients.
COVID-19
Is There any Alternative Receptor for SARS-CoV-2?
COVID-19
Novel Sigma 1 Receptor Antagonists as Potential Therapeutics for Pain Management.
COVID-19
Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies.
COVID-19
Predicted therapeutic targets for COVID-19 disease by inhibiting SARS-CoV-2 and its related receptors.
COVID-19
Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection.
COVID-19
SARS-CoV-2 Infection-Induced Promoter Hypomethylation as an Epigenetic Modulator of Heat Shock Protein A1L (HSPA1L) Gene.
COVID-19
The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection.
COVID-19
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
COVID-19
Ubiquitin-Modified Proteome of SARS-CoV-2-Infected Host Cells Reveals Insights into Virus-Host Interaction and Pathogenesis.
Coxsackievirus Infections
[The correlation research on miRNA378* and calumenin,endoplasmic reticulum stress,apoptosis in suckling mouse myocardial cells infected with coxsackie virus B3].
Craniocerebral Trauma
Alterations in inducible 72-kDa heat shock protein and the chaperone cofactor BAG-1 in human brain after head injury.
Creutzfeldt-Jakob Syndrome
Creutzfeldt-Jakob disease: heat shock protein 70 mRNA levels in mononuclear blood cells and clinical study.
Crohn Disease
Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding.
Crohn Disease
Autoimmunity to heat shock protein 40 in ulcerative colitis.
Crohn Disease
Cellular and humoral immunity to the 60-kD heat shock protein in inflammatory bowel disease.
Crohn Disease
Crohn's disease and polymorphism of heat shock protein gene HSP70-2 in the Chinese population.
Crohn Disease
Crohn's disease and polymorphism of heat shock protein gene HSP70-2 in the Tunisian population.
Crohn Disease
Detection of mycobacteria in Crohn's disease by a broad spectrum polymerase chain reaction.
Crohn Disease
Evidence for T lymphocyte reactivity to the 65 kilodalton heat shock protein of mycobacterium in active Crohn's disease.
Crohn Disease
Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation.
Crohn Disease
Heat shock protein 47 is a new candidate molecule as anti-fibrotic treatment of Crohn's disease.
Crohn Disease
Heat shock protein 90 and inflammatory activity in newly onset Crohn's disease.
Crohn Disease
Heat shock protein family A member 6 combined with clinical characteristics for the differential diagnosis of intestinal Behçet's disease.
Crohn Disease
Heat shock protein gene 70-2 polymorphism is differentially associated with the clinical phenotypes of ulcerative colitis and Crohn's disease.
Crohn Disease
Heat-shock protein HSP70-2 genotypes in patients with Crohn's disease: a more severe clinical course with intestinal complications in presence of the PstI-polymorphism.
Crohn Disease
How autophagy controls the intestinal epithelial barrier.
Crohn Disease
Hsp60 and Hsp10 increase in colon mucosa of Crohn's disease and ulcerative colitis.
Crohn Disease
Impaired humoral immune response against mycobacterial 65-kDa heat shock protein (HSP65) in patients with inflammatory bowel disease.
Crohn Disease
Increased Levels of Survivin, via Association With Heat Shock Protein 90, in Mucosal T Cells From Patients With Crohn's Disease.
Crohn Disease
Intestinal expression and cellular immune responses to human heat-shock protein 60 in Crohn's disease.
Crohn Disease
Intestinal expression of human heat shock protein 90 in patients with Crohn's disease and ulcerative colitis.
Crohn Disease
Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease.
Crohn Disease
Mucosal expression by B7-positive cells of the 60-kilodalton heat-shock protein in inflammatory bowel disease.
Crohn Disease
Polymorphism of heat-shock protein gene HSP70-2 in Crohn disease: possible genetic marker for two forms of Crohn disease.
Crohn Disease
Polymorphism of the heat-shock protein gene Hsp70-2, but not polymorphisms of the IL-10 and CD14 genes, is associated with the outcome of Crohn's disease.
Crohn Disease
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Crohn Disease
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.
Crohn Disease
Tumour necrosis factor-alpha production stimulated by heat shock protein 70 and its inhibition in circulating dendritic cells and cells eluted from mucosal tissues in Crohn's disease.
Cryptococcosis
A 77-kilodalton protein of Cryptococcus neoformans, a member of the heat shock protein 70 family, is a major antigen detected in the sera of mice with pulmonary cryptococcosis.
Cryptococcosis
Heat shock protein 70 (hsp70) as a major target of the antibody response in patients with pulmonary cryptococcosis.
Cryptogenic Organizing Pneumonia
Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis.
Cryptorchidism
EVEN-PLUS syndrome: A case report with novel variants in HSPA9 and evidence of HSPA9 gene dysfunction.
Cryptorchidism
Expression of HSP70-2 gene during germ cell apoptosis in rat unilateral cryptorchid testes.
Cryptorchidism
Inducible 70 kDa heat shock protein does not protect spermatogenic cells from damage induced by cryptorchidism.
Cryptosporidiosis
Survey of Cryptosporidium parvum genotypes in humans from the UK by mutation scanning analysis of a heat shock protein gene region.
Cushing Syndrome
Impaired wound healing in Cushing's syndrome: the role of heat shock proteins.
Cyclosporiasis
Genetic similarities between Cyclospora cayetanensis and cecum-infecting avian Eimeria spp. in apicoplast and mitochondrial genomes.
Cystic Fibrosis
A new role for heat shock factor 27 in the pathophysiology of Clostridium difficile toxin B.
Cystic Fibrosis
A small molecule that binds to an ATPase domain of Hsc70 promotes membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator.
Cystic Fibrosis
Antibodies to human HSP60 in patients with juvenile chronic arthritis, diabetes mellitus, and cystic fibrosis.
Cystic Fibrosis
Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis.
Cystic Fibrosis
Avidity of anti-P aeruginosa antibodies during chronic infection in patients with cystic fibrosis.
Cystic Fibrosis
BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.
Cystic Fibrosis
Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis.
Cystic Fibrosis
Coupling cystic fibrosis to endoplasmic reticulum stress: Differential role of Grp78 and ATF6.
Cystic Fibrosis
Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone.
Cystic Fibrosis
Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast.
Cystic Fibrosis
Extreme winter cold-induced osmoregulatory, metabolic, and physiological responses in European seabass (Dicentrarchus labrax) acclimatized at different salinities.
Cystic Fibrosis
How autophagy controls the intestinal epithelial barrier.
Cystic Fibrosis
Hsp104 facilitates the endoplasmic-reticulum-associated degradation of disease-associated and aggregation-prone substrates.
Cystic Fibrosis
Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast.
Cystic Fibrosis
Hsp90 and client protein maturation.
Cystic Fibrosis
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.
Cystic Fibrosis
Human heat shock protein 105/110 kDa (Hsp105/110) regulates biogenesis and quality control of misfolded cystic fibrosis transmembrane conductance regulator at multiple levels.
Cystic Fibrosis
Localization of the BiP molecular chaperone with respect to endoplasmic reticulum foci containing the cystic fibrosis transmembrane conductance regulator in yeast.
Cystic Fibrosis
Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation.
Cystic Fibrosis
Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.
Cystic Fibrosis
Relative increase in IgG antibodies to Pseudomonas aeruginosa 60-kDa GroEL in prediabetic patients with cystic fibrosis.
Cystic Fibrosis
Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation.
Cystic Fibrosis
Small changes in gene expression of targeted osmoregulatory genes when exposing marine and freshwater threespine stickleback (Gasterosteus aculeatus) to abrupt salinity transfers.
Cystic Fibrosis
Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR.
Cystic Fibrosis
The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients.
Cystic Fibrosis
The molecular chaperone Hsc70 assists the in vitro folding of the N-terminal nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator.
Cysts
A proteomic study on postdiapaused embryonic development of brine shrimp (Artemia franciscana).
Cysts
A role of carboxy-terminal region of Toxoplasma gondii-heat shock protein 70 in enhancement of T. gondii infection in mice.
Cysts
Acanthamoeba castellanii: Gene profile of encystation by ESTs analysis and KOG assignment.
Cysts
Artemin, a Diapause-Specific Chaperone, Contributes to the Stress Tolerance of Artemia Cysts and Influences Their Release from Females.
Cysts
Changes in the expression of Heat Shock Proteins in ovaries from bovines with cystic ovarian disease induced by ACTH.
Cysts
Chronic ingestion of high dosed Phikud Navakot extraction induces mesangiolysis in rats with alteration of AQP1 and Hsp60 expressions.
Cysts
Cyst viability and stress tolerance upon heat shock protein 70 knockdown in the brine shrimp Artemia franciscana.
Cysts
Expression of a 66-kD heat shock protein associated with the process of cyst formation of a true slime mold, Physarum polycephalum.
Cysts
Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD).
Cysts
Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice.
Cysts
Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.
Cysts
Isolation of Toxoplasma gondii development mutants identifies a potential proteophosphogylcan that enhances cyst wall formation.
Cysts
Knockdown of the Small Heat Shock Protein, p26 by RNA Interference Modifies the Diapause Proteome of Artemia franciscana.
Cysts
Levels of heat shock protein transcripts in normal follicles and ovarian follicular cysts.
Cysts
Mitosomes in trophozoites and cysts of the reptilian parasite Entamoeba invadens.
Cysts
Molecular chaperones, stress resistance and development in Artemia franciscana.
Cysts
Overexpression and extra-mitochondrial localization of the chaperonin Hsp60 in ameloblastoma.
Cysts
Post-diapause synthesis of ArHsp40-2, a type 2 J-domain protein from Artemia franciscana, is developmentally regulated and induced by stress.
Cysts
Profiling and quantifying differential gene transcription in Phytophthora infestans prior to and during the early stages of potato infection.
Cysts
Research on plant-parasitic nematode biology conducted by the United States Department of Agriculture-Agricultural Research Service.
Cysts
Stress tolerance during diapause and quiescence of the brine shrimp, Artemia.
Cysts
The consensus Nglyco -X-S/T motif and a previously unknown Nglyco -N-linked glycosylation are necessary for growth and pathogenicity of Phytophthora.
Cysts
The Small Heat Shock Protein p26 Aids Development of Encysting Artemia Embryos, Prevents Spontaneous Diapause Termination and Protects against Stress.
Cysts
Therapeutic Potential for CFTR Correctors in Autosomal Recessive Polycystic Kidney Disease.
Cysts
Water-structuring technology with the molecular chaperone proteins: indicated application of the ?-crystallin domains and imidazole-containing peptidomimetics in cosmetic skin care systems or dermatological therapeutic drug carrier formulations.
Cysts
[Heat shock protein of HSP70 family revealed in some contemporary freshwater Amoebae and in Acanthamoeba sp. from cysts isolated from permafrost samples]
Cytomegalovirus Infections
Interaction of antibodies against cytomegalovirus with heat-shock protein 60 in pathogenesis of atherosclerosis.
Cytomegalovirus Infections
NSF, Unc-18-1, dynamin-1 and HSP90 are inclusion body components in neuronal intranuclear inclusion disease identified by anti-SUMO-1-immunocapture.
Cytomegalovirus Infections
Prenatal diagnosis of congenital cytomegalovirus infection by detection of immunoglobulin M antibodies to the 70-kd heat shock protein in fetal serum.
Cytomegalovirus Infections
Role of the endoplasmic reticulum chaperone BiP, SUN domain proteins, and dynein in altering nuclear morphology during human cytomegalovirus infection.
Deafness
Ahsa1 and Hsp90 activity confers more severe craniofacial phenotypes in a zebrafish model of hypoparathyroidism, sensorineural deafness and renal dysplasia (HDR).
Decompression Sickness
Heat-shock protein 70 is involved in hyperbaric oxygen preconditioning on decompression sickness in rats.
Decompression Sickness
MEK1/2 Inhibition Synergistically Enhances the Preventive Effects of Normobaric Oxygen on Spinal Cord Injury in Decompression Sickness Rats.
Dehydration
Bulk analysis by resequencing and RNA-seq identifies candidate genes for maintaining leaf water content under water deficit in maize.
Dehydration
Changes in markers of muscle damage, inflammation and HSP70 after an Ironman Triathlon race.
Dehydration
Cloning of new members of heat shock protein HSP101 gene family in wheat (Triticum aestivum (L.) Moench) inducible by heat, dehydration, and ABA(1).
Dehydration
Dehydration stress alters the mitogen-activated-protein kinase signaling and chaperone stress response in Xenopus laevis.
Dehydration
Dehydration-induced DnaK2 Chaperone Is Involved in PSII Repair of a Desiccation-tolerant Cyanobacterium.
Dehydration
Heat shock proteins contribute to mosquito dehydration tolerance.
Dehydration
In defense of proteins: Chaperones respond to freezing, anoxia, or dehydration stress in tissues of freeze tolerant wood frogs.
Dehydration
Induction of Heat Shock Protein Messenger RNA in Maize Mesocotyls by Water Stress, Abscisic Acid, and Wounding.
Dehydration
Involvement of ascorbate peroxidase and heat shock proteins on citrus tolerance to combined conditions of drought and high temperatures.
Dehydration
LEA proteins prevent protein aggregation due to water stress.
Dehydration
Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration.
Dehydration
Preservative Effect of Polyols on the Stability of Biocatalysts during Short-term Dehydration Stress
Dehydration
Responses of the bed bug, Cimex lectularius, to temperature extremes and dehydration: levels of tolerance, rapid cold hardening and expression of heat shock proteins.
Dehydration
Targeting conserved co-opted host factors to block virus replication: Using allosteric inhibitors of the cytosolic Hsp70s to interfere with tomato bushy stunt virus replication.
Dehydration
The effect of dehydration on muscle metabolism and time trial performance during prolonged cycling in males.
Dehydration
The regulation of heat shock proteins in response to dehydration in Xenopus laevis.
Dehydration
The response of Asterochloris erici (Ahmadjian) Skaloud et Peksa to desiccation: a proteomic approach.
Dehydration
Uncovering the basis of viability loss in desiccation sensitive Trichilia dregeana seeds using differential quantitative protein expression profiling by iTRAQ.
Dehydration
[Construction and analysis of subtractive cDNA library of Phellodendron amurense under drought stress]
Delirium
Autopsy-proven Mirtazapine Withdrawal-induced Mania/Hypomania Associated with Sudden Death.
Delirium
Commentary on: Johnson MM, David JA, Michelhaugh SK, Schmidt CJ, Bannon MJ. Increased heat shock protein 70 gene expression in the brains of cocaine-related fatalities may be reflective of postdrug survival and intervention rather than excited delirium. J Forensic Sci 2012;57(6):1519-23.
Delirium
Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.
Delirium
Increased Heat Shock Protein 70 Gene Expression in the Brains of Cocaine-Related Fatalities may be Reflective of Postdrug Survival and Intervention rather than Excited Delirium.
Dementia
Dementia related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits A?42 toxicity in Drosophila.
Dementia
Heat shock protein 70 and tumor necrosis factor alpha in Taiwanese patients with dementia.
Dementia
Heat shock protein 70 mRNA levels in mononuclear blood cells from patients with dementia of the Alzheimer type.
Dementia
HSP90 and Its Novel Co-Chaperones, SGT1 and CHP-1, in Brain of Patients with Parkinson's Disease and Dementia with Lewy Bodies.
Dementia
Oral Administration of Lipopolysaccharide Prevents Cognitive Impairment in Streptozotocin-induced Diabetic Mice in a Blood Glucose-independent Manner.
Dementia
Stress protein inclusions in cerebral vessels in dialysis encephalopathy.
Dementia, Vascular
Heat shock protein 70 and tumor necrosis factor alpha in Taiwanese patients with dementia.
Demyelinating Diseases
Anti-alpha B-crystallin immunoreactivity in inflammatory nervous system diseases.
Demyelinating Diseases
Antibodies reactive to heat shock protein 90 induce oligodendrocyte precursor cell death in culture. Implications for demyelination in multiple sclerosis.
Demyelinating Diseases
Heat shock protein immunoreactivity in CSF: correlation with oligoclonal banding and demyelinating disease.
Demyelinating Diseases
Induction of Heat Shock Protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun.
Demyelinating Diseases
Induction of heat shock protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun.
Demyelinating Diseases
Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4- and MyD88-dependent pathway.
Demyelinating Diseases
miR-155-3p Drives the Development of Autoimmune Demyelination by Regulation of Heat Shock Protein 40.
Demyelinating Diseases
New Cortical Neurodegenerative Pathways in the Hypertensive Rat Brain.
Demyelinating Diseases
Targeting Heat Shock Protein 70 to Ameliorate c-Jun Expression and Improve Demyelinating Neuropathy.
Demyelinating Diseases
Tumor necrosis factor-alpha and alphaB-crystallin up-regulation during antibody-mediated demyelination in vitro: a putative protective mechanism in oligodendrocytes.
Dengue
A synthetic dengue virus antigen elicits enhanced antibody titers when linked to, but not mixed with, Mycobacterium tuberculosis HSP70 domain II.
Dengue
AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78.
Dengue
Dengue virus entry into liver (HepG2) cells is independent of hsp90 and hsp70.
Dengue
Dengue virus infection induces GRP78 which acts to chaperone viral antigen production.
Dengue
GRP78: a chaperone with diverse roles beyond the endoplasmic reticulum.
Dengue
GRP78: a multifunctional receptor on the cell surface.
Dengue
Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells.
Dengue
Hsp90 interacts with multiple dengue virus 2 proteins.
Dengue
Identification of GRP 78 (BiP) as a liver cell expressed receptor element for dengue virus serotype 2.
Dengue
RNA interference mediated inhibition of dengue virus multiplication and entry in HepG2 cells.
Dengue
RNA interference mediated silencing of Hsp60 gene in human monocytic myeloma cell line U937 revealed decreased dengue virus multiplication.
Dengue
Role of human GRP75 in miRNA mediated regulation of dengue virus replication.
Dengue
Small Molecule Inhibitor of ATPase Activity of HSP70 as a Broad-Spectrum Inhibitor against Flavivirus Infections.
Dental Caries
Heat Shock 70 Protein Genes and Genetic Susceptibility to Apical Periodontitis.
Dental Plaque
Inhibitory effects of low-energy pulsed ultrasonic stimulation on cell surface protein antigen C through heat shock proteins GroEL and DnaK in Streptococcus mutans.
Dental Plaque
The effect of IL-4 gene polymorphisms on cytokine production in patients with chronic periodontitis and in healthy controls.
Dental Pulp Calcification
Near-reciprocal phenotypes caused by inactivation or indiscriminate expression of the Drosophila segmentation gene ftz.
Dermatitis
Bacterial infection and tissue-specific Hsp72, -73 and -90 expression in western painted turtles.
Dermatitis Herpetiformis
Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis.
Dermatitis Herpetiformis
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Dermatitis, Atopic
Circulating heat shock protein 90 (Hsp90) and autoantibodies to Hsp90 are increased in patients with atopic dermatitis.
Dermatitis, Atopic
Expression of 27 KD, 65 KD and 72/73 KD heat shock protein in atopic dermatitis: comparison with those in normal skin and contact dermatitis.
Dermatitis, Atopic
Heat Shock Protein 27 kDa Content in Stratum Corneum Correlates with Severity of Atopic Dermatitis.
Dermatitis, Atopic
Heat shock protein HSP40 family chaperone DNAJB6/MRJ expression analysis in blood cells obtained from patients with atopic dermatitis in different phases.
Dermatitis, Atopic
Intradermal injection of Hsp60 induces cytokine responses in canine atopic and healthy skin.
Dermatitis, Atopic
Recognition of self-heat shock protein 60 by T cells from patients with atopic dermatitis.
Dermatitis, Atopic
Subcutaneous injection of recombinant heat shock protein 70 ameliorates atopic dermatitis skin lesions in a mouse model.
Dermatitis, Atopic
[Expression of HSP60, TLR4 and NF-kappaBp65 in the peripheral blood of patients with atopic dermatitis]
Dermatitis, Contact
Attenuation of contact hypersensitivity by cell-permeable heat shock protein 70 in BALB/c mouse model.
Dermatitis, Contact
Expression of 27 KD, 65 KD and 72/73 KD heat shock protein in atopic dermatitis: comparison with those in normal skin and contact dermatitis.
Dermatomyositis
A dual role for HSP90 and HSP70 in the inflammatory myopathies: from muscle fiber protection to active invasion by macrophages.
Dermatomyositis
Expression of heat-shock/stress proteins in Duchenne muscular dystrophy.
Dermatomyositis
Heat-shock protein 90 and ubiquitin: developmental regulation during myogenesis.
Dermatomyositis
Hsp60 in inflamed muscle tissue is the target of regulatory autoreactive T cells in patients with juvenile dermatomyositis.
Dermatomyositis
Incidence of anti Hsp 90 and 70 antibodies in children with SLE, juvenile dermatomyositis and juvenile chronic arthritis.
Dermatomyositis
[Expression of the heat shock protein 70 in inflammatory myopathies]
Diabetes Complications
Enhanced degradation and decreased stability of eye lens alpha-crystallin upon methylglyoxal modification.
Diabetes Complications
Heat shock protein 60 (HSP60) modulates adiponectin signaling by stabilizing adiponectin receptor.
Diabetes Complications
Serum heat shock protein 27 and diabetes complications in the EURODIAB prospective complications study: a novel circulating marker for diabetic neuropathy.
Diabetes Complications
Targeting HSP90 Ameliorates Nephropathy and Atherosclerosis Through Suppression of NF-?B and STAT Signaling Pathways in Diabetic Mice.
Diabetes Insipidus, Nephrogenic
Hsp90 inhibitor partially corrects nephrogenic diabetes insipidus in a conditional knock-in mouse model of aquaporin-2 mutation.
Diabetes Mellitus
A model integrating donor gene polymorphisms predicts fibrosis after liver transplantation.
Diabetes Mellitus
Acetylation of Hsp90 reverses dexamethasone-mediated inhibition of insulin secretion.
Diabetes Mellitus
Antibodies against different epitopes of heat-shock protein 60 in children with type 1 diabetes mellitus.
Diabetes Mellitus
Antibodies to heat shock protein 65 kD in type 1 diabetes mellitus.
Diabetes Mellitus
Antibodies to heat-shock protein 65 and neopterin levels in patients with type 1 diabetes mellitus.
Diabetes Mellitus
Antibodies to human HSP60 in patients with juvenile chronic arthritis, diabetes mellitus, and cystic fibrosis.
Diabetes Mellitus
Chaperone-Based Therapeutic Target Innovation: Heat Shock Protein 70 (HSP70) for Type 2 Diabetes Mellitus.
Diabetes Mellitus
Chlamydia pneumoniae, heat shock proteins 60 and risk of secondary cardiovascular events in patients with coronary heart disease under special consideration of diabetes : a prospective study.
Diabetes Mellitus
Complement C4 and heat shock protein 70 (HSP70) genotypes and type I diabetes mellitus.
Diabetes Mellitus
Detection of Hsp60 in saliva and serum from type 2 diabetic and non-diabetic control subjects.
Diabetes Mellitus
Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?
Diabetes Mellitus
Effect of heat shock protein peptide DiaPep277 on beta-cell function in paediatric and adult patients with recent-onset diabetes mellitus type 1: two prospective, randomized, double-blind phase II trials Nanette C. Schloot, Guido Meierhoff, Csaba Lengyel, Gyözö Vándorfi, József Takács, Pál Pánczél, László Barkai, László Madácsy, Tamás Oroszlán, Peter Kovács, Gábor Sütö, Tadej Battelino, Nora Hosszufalusi, György Jermendy. Diabetes/Metabolism Research and Reviews 2006.
Diabetes Mellitus
Effect of heat shock protein peptide DiaPep277 on beta-cell function in paediatric and adult patients with recent-onset diabetes mellitus type 1: two prospective, randomized, double-blind phase II trials.
Diabetes Mellitus
Endothelial TNF-? induction by Hsp60 secreted from THP-1 monocytes exposed to hyperglycaemic conditions.
Diabetes Mellitus
Express ELISA for detection of mortalin.
Diabetes Mellitus
Glutamine enhances the heat shock protein 70 expression as a cardioprotective mechanism in left heart tissues in the presence of diabetes mellitus.
Diabetes Mellitus
Heat Shock Protein 70 Gene Polymorphism in Egyptian Patients with Type 2 Diabetes Mellitus, with and without Nephropathy.
Diabetes Mellitus
Heat Shock Protein HSP60 in Left Ventricular Cardiomyocytes of Hypertensive Rats with and without Insulin-Dependent Diabetes Mellitus.
Diabetes Mellitus
Heat shock protein-70 and hypoxia inducible factor-1? in type 2 diabetes mellitus patients complicated with retinopathy.
Diabetes Mellitus
Higher urine heat shock protein 70/creatinine ratio in type 1 diabetes mellitus.
Diabetes Mellitus
Is heat shock protein 60 associated with type 2 diabetes mellitus?
Diabetes Mellitus
Ischemic preconditioning phosphorylates mitogen-activated kinases and heat shock protein 27 in the diabetic rat heart.
Diabetes Mellitus
Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials.
Diabetes Mellitus
Peptide therapy for Type I diabetes: the immunological homunculus and the rationale for vaccination.
Diabetes Mellitus
Polymorphism of HSP70 gene is not associated with type 1 (insulin-dependent) diabetes mellitus in Japanese.
Diabetes Mellitus
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Diabetes Mellitus
Protein kinase A-dependent translocation of Hsp90 alpha impairs endothelial nitric-oxide synthase activity in high glucose and diabetes.
Diabetes Mellitus
Purification of recombinant human Hsp60: use of a GroEL-free preparation to assess autoimmunity in rheumatoid arthritis.
Diabetes Mellitus
Restoring HSP70 Deficiencies Improves Glucose Tolerance in Diabetic Monkeys.
Diabetes Mellitus
Sequence homologies between hsp60 and autoantigens.
Diabetes Mellitus
T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides.
Diabetes Mellitus
Th1 and Th2 cell responses of type 1 diabetes patients and healthy controls to human heat-shock protein 60 peptides AA437-460 and AA394-408.
Diabetes Mellitus
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
Diabetes Mellitus
[The role of hsp60 and hsp70 kDa heat shock protein families in different types of diabetes mellitus]
Diabetes Mellitus, Type 1
A rapid method to study heat shock protein 70-2 gene polymorphism in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
A role of Hsp60 in autoimmune diabetes: analysis in a transgenic model.
Diabetes Mellitus, Type 1
Analysis of serum Hsp90 as a potential biomarker of ? cell autoimmunity in type 1 diabetes.
Diabetes Mellitus, Type 1
Antibodies to heat shock protein 65 kD in type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Autoimmune diabetes induced by the beta-cell toxin STZ. Immunity to the 60-kDa heat shock protein and to insulin.
Diabetes Mellitus, Type 1
Characterization of human DNA topoisomerase II as an autoantigen recognized by patients with IDDM.
Diabetes Mellitus, Type 1
Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes.
Diabetes Mellitus, Type 1
Deficient heat shock protein 70 response to stress in leukocytes at onset of type 1 diabetes.
Diabetes Mellitus, Type 1
Detection of autoantibodies to the pancreatic islet heat shock protein 60 in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Detection of heat shock protein in patients with insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
Diabetes mellitus in cystic fibrosis: genetic and immunological markers.
Diabetes Mellitus, Type 1
Effect of heat shock protein peptide DiaPep277 on beta-cell function in paediatric and adult patients with recent-onset diabetes mellitus type 1: two prospective, randomized, double-blind phase II trials.
Diabetes Mellitus, Type 1
Effect of intrathymic administration of mycobacterial heat shock protein 65 and peptide p277 on the development of diabetes in NOD mice: caution required in vaccination studies.
Diabetes Mellitus, Type 1
Enhanced immunogenicity of peptide P277 by heat shock protein HSP65 vector carrying tandem repeats of P277 to prevent type 1 diabetes in NOD mice.
Diabetes Mellitus, Type 1
Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes.
Diabetes Mellitus, Type 1
Heat shock protein 27 is associated with better nerve function and fewer signs of neuropathy.
Diabetes Mellitus, Type 1
Heat shock protein 60 elicits abnormal response in macrophages of diabetes-prone non-obese diabetic mice.
Diabetes Mellitus, Type 1
Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy.
Diabetes Mellitus, Type 1
Heat Shock Protein HSP60 in Left Ventricular Cardiomyocytes of Hypertensive Rats with and without Insulin-Dependent Diabetes Mellitus.
Diabetes Mellitus, Type 1
Higher urine heat shock protein 70/creatinine ratio in type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progression.
Diabetes Mellitus, Type 1
Immunomodulation with heat shock protein DiaPep277 to preserve beta cell function in type 1 diabetes - an update.
Diabetes Mellitus, Type 1
Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein.
Diabetes Mellitus, Type 1
Induction of diabetes in standard mice by immunization with the p277 peptide of a 60-kDa heat shock protein.
Diabetes Mellitus, Type 1
Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.
Diabetes Mellitus, Type 1
Investigation of endoplasmic reticulum stress and sonic hedgehog pathway in diabetic liver injury in mice.
Diabetes Mellitus, Type 1
Molecular mimicry between varicella, measles virus and Hsp60 in type 1 diabetes associated HLA-DR3/DR4 molecules.
Diabetes Mellitus, Type 1
No independent association between HSP70 gene polymorphism and IDDM.
Diabetes Mellitus, Type 1
NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells.
Diabetes Mellitus, Type 1
Oral administration of Lactococcus lactis-expressing heat shock protein 65 and tandemly repeated IA2P2 prevents type 1 diabetes in NOD mice.
Diabetes Mellitus, Type 1
Polymorphic analysis of the human MHC-linked heat shock protein 70 (HSP70-2) and HSP70-Hom genes in insulin-dependent diabetes mellitus (IDDM).
Diabetes Mellitus, Type 1
Production and purification of a recombinant human hsp60 epitope using the cellulose-binding domain in Escherichia coli.
Diabetes Mellitus, Type 1
Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes.
Diabetes Mellitus, Type 1
Promotion of atherosclerosis in high cholesterol diet-fed rabbits by immunization with the P277 peptide.
Diabetes Mellitus, Type 1
Proteomic characterization of pancreatic islet {beta}-cells stimulated with pancreatic carcinoma cell conditioned medium.
Diabetes Mellitus, Type 1
Recognition of heat shock protein 60 epitopes in children with type 1 diabetes.
Diabetes Mellitus, Type 1
Secretory granule autoantigen in insulin-dependent diabetes mellitus is related to 62 kDa heat-shock protein (hsp60).
Diabetes Mellitus, Type 1
Sequence homology of the diabetes-associated autoantigen glutamate decarboxylase with coxsackie B4-2C protein and heat shock protein 60 mediates no molecular mimicry of autoantibodies.
Diabetes Mellitus, Type 1
T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides.
Diabetes Mellitus, Type 1
T cells and autoantibodies to human HSP70 in type 1 diabetes in children.
Diabetes Mellitus, Type 1
Targeted delivery of antigen to intestinal dendritic cells induces oral tolerance and prevents autoimmune diabetes in NOD mice.
Diabetes Mellitus, Type 1
The hsp60 peptide p277 arrests the autoimmune diabetes induced by the toxin streptozotocin.
Diabetes Mellitus, Type 1
The pathogenicity of islet-infiltrating lymphocytes in the non-obese diabetic (NOD) mouse.
Diabetes Mellitus, Type 1
Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients.
Diabetes Mellitus, Type 1
Transgenic Expression of Hsc70 in Pancreatic Islets Enhances Autoimmune Diabetes in Response to {beta} Cell Damage.
Diabetes Mellitus, Type 1
Treatment of autoimmune diabetes and insulitis in NOD mice with heat shock protein 60 peptide p277.
Diabetes Mellitus, Type 1
Treatment of new-onset type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: extension of a randomized, double-blind, phase II trial.
Diabetes Mellitus, Type 1
Type 1 diabetes alters anti-hsp90 autoantibody isotype.
Diabetes Mellitus, Type 1
Vaccination of non-obese diabetic mice with a fragment of peptide P277 attenuates insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 1
[High-dose heat shock protein gp96 immunization prevents type 1 diabetes via inducing regulatory T cells].
Diabetes Mellitus, Type 1
[Improved efficacy of P277 fused to heat shock protein 65 of Mycobacterium tuberculosis against diabetes in nonobese diabetic mice]
Diabetes Mellitus, Type 1
[Intranasal vaccination with mycobacterial 65-kD heat-shock protein can prevent insulitis and diabetes in non-obese diabetic mice].
Diabetes Mellitus, Type 2
1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.
Diabetes Mellitus, Type 2
Antibodies to heat-shock protein 65 and neopterin levels in patients with type 1 diabetes mellitus.
Diabetes Mellitus, Type 2
Association Between Promoter Polymorphisms of the GRP78 Gene and Risk of Type 2 Diabetes in a Chinese Han Population.
Diabetes Mellitus, Type 2
Association of extracellular heat shock protein 70 and insulin resistance in type 2 diabetes; independent of obesity and C-reactive protein.
Diabetes Mellitus, Type 2
Association of humoral immunity to human Hsp60 with the IL-6 gene polymorphism C-174G in patients with type 2 diabetes and controls.
Diabetes Mellitus, Type 2
Association of polymorphism in heat shock protein 70 genes with type 2 diabetes in Bangladeshi population.
Diabetes Mellitus, Type 2
Attenuation of exercise-induced heat shock protein 72 expression blunts improvements in whole-body insulin resistance in rats with type 2 diabetes.
Diabetes Mellitus, Type 2
Central Acting Hsp10 Regulates Mitochondrial Function, Fatty Acid Metabolism, and Insulin Sensitivity in the Hypothalamus.
Diabetes Mellitus, Type 2
Chaperone-Based Therapeutic Target Innovation: Heat Shock Protein 70 (HSP70) for Type 2 Diabetes Mellitus.
Diabetes Mellitus, Type 2
Circulating heat shock protein 27 as a novel marker of subclinical atherosclerosis in type 2 diabetes: a cross-sectional community-based study.
Diabetes Mellitus, Type 2
Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice.
Diabetes Mellitus, Type 2
Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance.
Diabetes Mellitus, Type 2
Decreased Thioredoxin-1 and Increased HSP90 Expression in Skeletal Muscle in Subjects with Type 2 Diabetes or Impaired Glucose Tolerance.
Diabetes Mellitus, Type 2
Detection of autoantibodies to the pancreatic islet heat shock protein 60 in insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Detection of Hsp60 in saliva and serum from type 2 diabetic and non-diabetic control subjects.
Diabetes Mellitus, Type 2
Elevated levels of heat-shock protein 70 (HSP70) in the mononuclear cells of patients with non-insulin-dependent diabetes mellitus.
Diabetes Mellitus, Type 2
Exercise training improves basal blood glucose metabolism with no changes of cytosolic inhibitor B kinase or c-Jun N-terminal kinase activation in skeletal muscle of Otsuka Long-Evans Tokushima fatty rats.
Diabetes Mellitus, Type 2
Heat shock protein 70 and albuminuria in patients with type 2 diabetes: a matched case control study.
Diabetes Mellitus, Type 2
Heat Shock Protein 70 Gene Polymorphism in Egyptian Patients with Type 2 Diabetes Mellitus, with and without Nephropathy.
Diabetes Mellitus, Type 2
Heat shock protein studies in type 1 and type 2 diabetes and human islet cell culture.
Diabetes Mellitus, Type 2
Heat shock protein-70 and hypoxia inducible factor-1? in type 2 diabetes mellitus patients complicated with retinopathy.
Diabetes Mellitus, Type 2
Heat shock treatment with mild electrical stimulation safely reduced inflammatory markers in healthy male subjects.
Diabetes Mellitus, Type 2
HSP72 protects against obesity-induced insulin resistance.
Diabetes Mellitus, Type 2
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism.
Diabetes Mellitus, Type 2
Is heat shock protein 60 associated with type 2 diabetes mellitus?
Diabetes Mellitus, Type 2
Leptin regulation of Hsp60 impacts hypothalamic insulin signaling.
Diabetes Mellitus, Type 2
Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials.
Diabetes Mellitus, Type 2
Plasma heat shock protein response to euglycemia in type 2 diabetes.
Diabetes Mellitus, Type 2
Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity.
Diabetes Mellitus, Type 2
Predicted therapeutic targets for COVID-19 disease by inhibiting SARS-CoV-2 and its related receptors.
Diabetes Mellitus, Type 2
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Diabetes Mellitus, Type 2
Proteomic analysis of primary cultures of human adipose-derived stem cells: modulation by Adipogenesis.
Diabetes Mellitus, Type 2
Serum heat shock protein 70 and oxidized LDL in patients with type 2 diabetes: does sex matter?
Diabetes Mellitus, Type 2
The chaperone balance hypothesis: the importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical management.
Diabetes Mellitus, Type 2
The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes.
Diabetes Mellitus, Type 2
The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.
Diabetes Mellitus, Type 2
The lost correlation between heat shock protein 70 (HSPA1A) and plasminogen activator inhibitor-1 in patients with type 2 diabetes and albuminuria.
Diabetes Mellitus, Type 2
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
Diabetes Mellitus, Type 2
[Effects of curcumin on protein expression of glucose regulated protein 78 and caspase-12 of myocardial endoplasmic reticulum stress related factors in type 2 diabetes rats].
Diabetes, Gestational
Increased circulating heat shock protein 70 (HSPA1A) levels in gestational diabetes mellitus: a pilot study.
Diabetic Cardiomyopathies
Exercise modulates heat shock protein 27 activity in diabetic cardiomyopathy.
Diabetic Cardiomyopathies
Heat shock protein 60 (HSP60) modulates adiponectin signaling by stabilizing adiponectin receptor.
Diabetic Cardiomyopathies
Hsp10 and Hsp60 suppress ubiquitination of insulin-like growth factor-1 receptor and augment insulin-like growth factor-1 receptor signaling in cardiac muscle: implications on decreased myocardial protection in diabetic cardiomyopathy.
Diabetic Cardiomyopathies
IGF-I is a matter of heart.
Diabetic Cardiomyopathies
Insulin deficiency downregulated heat shock protein 60 and IGF-1 receptor signaling in diabetic myocardium.
Diabetic Cardiomyopathies
Tanshinone IIA ameliorates diabetic cardiomyopathy by inhibiting Grp78 and CHOP expression in STZ-induced diabetes rats.
Diabetic Cardiomyopathies
The carboxyl terminus of heat shock protein 70-interacting protein (CHIP) participates in high glucose-induced cardiac injury.
Diabetic Cardiomyopathies
[The effect and mechanism of heat shock protein 47 on streptozotocin-induced diabetic cardiomyopathy].
Diabetic Foot
Heat Shock Protein 70 Gene Single Nucleotide Polymorphism and Diabetic Foot Ulcer. Is There Any Relationship?
Diabetic Foot
Heat-shock protein 70 gene polymorphism is associated with the severity of diabetic foot ulcer and the outcome of surgical treatment.
Diabetic Ketoacidosis
Diabetic ketoacidosis increases extracellular levels of the major inducible 70-kDa heat shock protein.
Diabetic Nephropathies
Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease.
Diabetic Nephropathies
Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy.
Diabetic Nephropathies
Alpha-lipoic Acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney.
Diabetic Nephropathies
Association of A1538G and C2437T single nucleotide polymorphisms in heat shock protein-70 genes with diabetic nephropathy among South Indian population.
Diabetic Nephropathies
Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy.
Diabetic Nephropathies
Coexpression of collagens and collagen-binding heat shock protein 47 in human diabetic nephropathy and IgA nephropathy.
Diabetic Nephropathies
Heat shock protein expression in diabetic nephropathy.
Diabetic Nephropathies
Levels of circulating GRP78 and CHOP in endoplasmic reticulum stress pathways in Chinese type 2 diabetic kidney disease patients.
Diabetic Nephropathies
Stress proteins in glomerular epithelial cell injury.
Diabetic Nephropathies
[Role of heat shock protein 47 on experimental diabetic nephropathy of rats]
Diabetic Neuropathies
Induction of heat shock proteins may combat insulin resistance.
Diabetic Neuropathies
Serum heat shock protein 27 and diabetes complications in the EURODIAB prospective complications study: a novel circulating marker for diabetic neuropathy.
Diabetic Retinopathy
Catechin Weakens Diabetic Retinopathy by Inhibiting the Expression of NF-?B Signaling Pathway-Mediated Inflammatory Factors.
Diabetic Retinopathy
Elevated Activating Transcription Factor 4 and Glucose-Regulated 78 Kda Protein Levels Correlate with Inflammatory Cytokines in the Aqueous Humor and Vitreous of Proliferative Diabetic Retinopathy.
Diabetic Retinopathy
Heat shock protein-70 and hypoxia inducible factor-1? in type 2 diabetes mellitus patients complicated with retinopathy.
Diffuse Axonal Injury
The expression and changes of heat shock protein 70, MDA and haemorheology in rat cortex after diffuse axonal injury with secondary insults.
Digestive System Neoplasms
The Clinical Value of HSP60 in Digestive System Cancers: a Systematic Review and Meta-Analysis.
Digestive System Neoplasms
The role of ferroptosis in digestive system cancer.
Diphtheria
Heat shock proteins induce pores in membranes.
Diphtheria
Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.
Diphtheria
Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing.
Diphtheria
Potential of anti-Candida antibodies in immunoprophylaxis.
Diphtheria
Protective antitumor immunity induced by tumor cell lysates conjugated with diphtheria toxin and adjuvant epitope in mouse breast tumor models.
Diphtheria
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.
Distal Myopathies
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.
Distal Myopathies
A novel heterozygous mutation in the C-terminal region of HSPB8 leads to limb-girdle rimmed vacuolar myopathy.
Distemper
Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity.
Distemper
Enhanced production of morbillivirus gene-specific RNAs following induction of the cellular stress response in stable persistent infection.
Down Syndrome
Beta-glucan's varying structure characteristics modulate survival and immune-related genes expression from Vibrio harveyi-infected Artemia franciscana in gnotobiotic conditions.
Down Syndrome
Heat-shock protein 70 levels in brain of patients with Down syndrome and Alzheimer's disease.
Down Syndrome
Upregulation of phosphorylated alphaB-crystallin in the brain of children and young adults with Down syndrome.
Drug-Related Side Effects and Adverse Reactions
Consequences of heat shock protein 72 (Hsp72) expression and activity on stress-induced apoptosis in CD30(+) NPM-ALK(+) anaplastic large-cell lymphomas.
Drug-Related Side Effects and Adverse Reactions
Geranylgeranylacetone prevents acute liver damage after massive hepatectomy in rats through suppression of a CXC chemokine GRO1 and induction of heat shock proteins.
Drug-Related Side Effects and Adverse Reactions
Heat Shock Protein 90 Inhibitors as Broad Spectrum Anti-infectives.
Dry Eye Syndromes
Interferon-?-Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sjögren Syndrome.
Dry Eye Syndromes
Proteomics Differentiate Between Thyroid-Associated Orbitopathy and Dry Eye Syndrome.
Dry Eye Syndromes
Therapeutic Potential of the Molecular Chaperone and Matrix Metalloproteinase Inhibitor Clusterin for Dry Eye.
Duodenal Ulcer
Polymorphisms in TNF and HSP-70 show a significant association with gastric cancer and duodenal ulcer.
Duodenal Ulcer
Potential antigen candidates for subunit vaccine development against Helicobacter pylori infection.
Duodenal Ulcer
Role of Heat-Shock Protein (HSP) 70-2 Genotype in Peptic Ulcer in Japanese Population.
Duodenogastric Reflux
Injury to the gastric mucosa and cellular dynamics in a rat model of duodenogastric reflux: the possible significance of gastrin induction and a heat shock protein.
Dysentery, Amebic
Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.
Dyslexia
A novel role for DYX1C1, a chaperone protein for both Hsp70 and Hsp90, in breast cancer.
Dyslipidemias
1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.
Dyslipidemias
Dietary supplementation of brown seaweed (Sargassum latifolium) alleviates the environmental heat stress-induced toxicity in male Barki sheep (Ovis aries).
Dyslipidemias
Effect of dyslipidemia on intima-media thickness of intra- and extracranial atherosclerosis by regulating the expression of hsp70 in rabbits.
Dyslipidemias
Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study.
Dystonia
CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process.
Dystonia
Expression of TorsinA in a heterologous yeast system reveals interactions with lumenal domains of LINC and nuclear pore complex components.
Dystonia
Human TorsinA can function in the yeast cytosol as a molecular chaperone.
Dystonia
LULL1 Retargets TorsinA to the Nuclear Envelope Revealing an Activity that Is Impaired by the DYT1 Dystonia Mutation.
Dystonia
Miniature release events of glutamate from hippocampal neurons are influenced by the dystonia-associated protein torsinA.
Dystonia
Synaptic vesicle recycling is enhanced by torsinA that harbors the DYT1 dystonia mutation.
Dystonia Musculorum Deformans
Resolving the TorsinA Oligomerization Conundrum: The Glycan Hypothesis.
Dystonia Musculorum Deformans
The BiP molecular chaperone plays multiple roles during the biogenesis of TorsinA, a AAA+ ATPase associated with the neurological disease Early-Onset Torsion Dystonia.
Dystonia Musculorum Deformans
The early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitro.
Dystonia Musculorum Deformans
TorsinA participates in endoplasmic reticulum-associated degradation.
Dystonic Disorders
Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.
Echinococcosis
Molecular and immunological characterization of the C-terminal region of a new Echinococcus granulosus Heat Shock Protein 70.
Echinococcosis
Serological reactivity to heat shock protein 70 in patients with hydatid disease.
Ehrlichiosis
Aggregate-reactivation activity of the molecular chaperone ClpB from Ehrlichia chaffeensis.
Ehrlichiosis
Characterization of an immunoreactive protein from the agent of human granulocytic ehrlichiosis.
Ehrlichiosis
Heat shock protein 70 of the agent of human granulocytic ehrlichiosis binds to Borrelia burgdorferi antibodies.
Elephantiasis, Filarial
Biochemical characterization and evaluation of a Brugia malayi small heat shock protein as a vaccine against lymphatic filariasis.
Elephantiasis, Filarial
Brugia malayi Wolbachia hsp60 IgG antibody and isotype reactivity in different clinical groups infected or exposed to human bancroftian lymphatic filariasis.
Elephantiasis, Filarial
Characterization of an hsp70 gene from the human filarial parasite, Brugia malayi (Nematoda).
Elephantiasis, Filarial
Heat shock cognate 70 is a prominent immunogen in Brugian filariasis.
Elephantiasis, Filarial
Localization of paramyosin, myosin, and a heat shock protein 70 in larval and adult Brugia malayi.
Embolic Stroke
Correlation of diffusion MRI and heat shock protein in a rat embolic stroke model.
Encephalitis
Geldanamycin, a ligand of heat shock protein 90, inhibits herpes simplex virus type 2 replication both in vitro and in vivo.
Encephalitis
HSP-70-Mediated Hyperbaric Oxygen Reduces Brain and Pulmonary Edema and Cognitive Deficits in Rats in a Simulated High-Altitude Exposure.
Encephalitis
miR-16-1 expression, heat shock protein 70 and inflammatory reactions in astrocytes of mice with epilepsy induced by encephalitis B virus infection.
Encephalitis
Oral administration of HSP-containing E. coli extract OM-89 has suppressive effects in autoimmunity. Regulation of autoimmune processes by modulating peripheral immunity towards hsp's?
Encephalitis
Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells.
Encephalitis, Japanese
A KDEL Retrieval System for ER-Golgi Transport of Japanese Encephalitis Viral Particles.
Encephalitis, Japanese
Association of heat-shock protein 70 with lipid rafts is required for Japanese encephalitis virus infection in Huh7 cells.
Encephalitis, Japanese
Correction: Japanese encephalitis virus co-opts the ER-stress response protein GRP78 for viral infectivity.
Encephalitis, Japanese
Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling.
Encephalitis, Japanese
GRP78 Is an Important Host Factor for Japanese Encephalitis Virus Entry and Replication in Mammalian Cells.
Encephalitis, Japanese
Heat shock cognate protein 70 isoform D is required for clathrin-dependent endocytosis of Japanese encephalitis virus in C6/36cells.
Encephalitis, Japanese
Heat Shock Protein 70 Is Associated with Replicase Complex of Japanese Encephalitis Virus and Positively Regulates Viral Genome Replication.
Encephalitis, Japanese
Heat shock protein 70 on Neuro2a cells is a putative receptor for Japanese encephalitis virus.
Encephalitis, Japanese
Heat shock protein 90? in the Vero cell membrane binds Japanese encephalitis virus.
Encephalitis, Japanese
Hsp40 Protein DNAJB6 Interacts with Viral NS3 and Inhibits the Replication of the Japanese Encephalitis Virus.
Encephalitis, Japanese
HSP60 critically regulates endogenous IL-1? production in activated microglia by stimulating NLRP3 inflammasome pathway.
Encephalitis, Japanese
Identification of Heat Shock Protein 90 Beta in JEV-Induced Secretion Proteins.
Encephalitis, Japanese
Japanese encephalitis virus co-opts the ER-stress response protein GRP78 for viral infectivity.
Encephalitis, Japanese
Japanese encephalitis virus induces human neural stem/progenitor cell death by elevating GRP78, PHB and hnRNPC through ER stress.
Encephalitis, Japanese
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage.
Encephalomyelitis
Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.
Encephalomyelitis
Brain-derived heat shock protein 70-Peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.
Encephalomyelitis
EAE tolerance induction with Hsp70-peptide complexes depends on H60 and NKG2D activity.
Encephalomyelitis
Experimental autoimmune encephalomyelitis. Qualitative and semiquantitative differences in heat shock protein 60 expression in the central nervous system.
Encephalomyelitis
Heat shock protein 27 upregulation and phosphorylation in rat experimental autoimmune encephalomyelitis.
Encephalomyelitis
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Encephalomyelitis
Heat shock proteins and experimental autoimmune encephalomyelitis (EAE): I. Immunization with a peptide of the myelin protein 2',3' cyclic nucleotide 3' phosphodiesterase that is cross-reactive with a heat shock protein alters the course of EAE.
Encephalomyelitis
Hsp70 regulates immune response in experimental autoimmune encephalomyelitis.
Encephalomyelitis
miR-155-3p Drives the Development of Autoimmune Demyelination by Regulation of Heat Shock Protein 40.
Encephalomyelitis
Role of hsp90 in systemic lupus erythematosus and its clinical relevance.
Encephalomyelitis
Subcellular localisation of Theiler's murine encephalomyelitis virus (TMEV) capsid subunit VP1 vis-á-vis host protein Hsp90.
Encephalomyelitis
The 70-kDa heat shock cognate protein (HSC70) is a major constituent of the central nervous system and is up-regulated only at the mRNA level in acute experimental autoimmune encephalomyelitis.
Encephalomyelitis
The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.
Encephalomyelitis
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism.
Encephalomyelitis
[Protective effects of heat shock preconditioning on the experimental autoimmune encephalomyelitis rats]
Encephalomyelitis, Autoimmune, Experimental
Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.
Encephalomyelitis, Autoimmune, Experimental
Brain-derived heat shock protein 70-Peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Characterization of migration parameters on peripheral and central nervous system T cells following treatment of experimental allergic encephalomyelitis with CRYAB.
Encephalomyelitis, Autoimmune, Experimental
CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients.
Encephalomyelitis, Autoimmune, Experimental
EAE tolerance induction with Hsp70-peptide complexes depends on H60 and NKG2D activity.
Encephalomyelitis, Autoimmune, Experimental
Experimental autoimmune encephalomyelitis. Qualitative and semiquantitative differences in heat shock protein 60 expression in the central nervous system.
Encephalomyelitis, Autoimmune, Experimental
Heat shock protein 27 upregulation and phosphorylation in rat experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Heat shock proteins and experimental autoimmune encephalomyelitis (EAE): I. Immunization with a peptide of the myelin protein 2',3' cyclic nucleotide 3' phosphodiesterase that is cross-reactive with a heat shock protein alters the course of EAE.
Encephalomyelitis, Autoimmune, Experimental
Hsp70 regulates immune response in experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
miR-155-3p Drives the Development of Autoimmune Demyelination by Regulation of Heat Shock Protein 40.
Encephalomyelitis, Autoimmune, Experimental
The 70-kDa heat shock cognate protein (HSC70) is a major constituent of the central nervous system and is up-regulated only at the mRNA level in acute experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Towards peptide immunotherapy in rheumatoid arthritis: competitor-modulator concept.
Encephalomyelitis, Autoimmune, Experimental
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism.
Encephalomyelitis, Autoimmune, Experimental
[Protective effects of heat shock preconditioning on the experimental autoimmune encephalomyelitis rats]
Encephalopathy, Bovine Spongiform
Stress response in the central nervous system of a transgenic mouse model of bovine spongiform encephalopathy.
Endocarditis
Cloning and sequencing of a part of the heat shock protein 65 gene (hsp65) of "Tropheryma whippelii" and its use for detection of "T. whippelii" in clinical specimens by PCR.
Endocarditis
Enhanced levels of Staphylococcus aureus stress protein GroEL and DnaK homologs early in infection of human epithelial cells.
Endocarditis
Global distribution of Bartonella infections in domestic bovine and characterization of Bartonella bovis strains using multi-locus sequence typing.
Endocarditis
In the Search of Potential Serodiagnostic Proteins to Discriminate Between Acute and Chronic Q Fever in Humans. Some Promising Outcomes.
Endocarditis
Prosthetic Valve Endocarditis with Bartonella washoensis in a Human European Patient and Its Detection in Red Squirrels (Sciurus vulgaris).
Endocarditis
Streptococcus tigurinus is frequent among gtfR-negative Streptococcus oralis isolates and in the human oral cavity, but highly virulent strains are uncommon.
Endometrial Hyperplasia
Autophagy in the physiological endometrium and cancer.
Endometrial Hyperplasia
Over-expression of heat shock proteins in carcinogenic endometrium.
Endometrial Hyperplasia
[Expression and significance of heat shock protein 70, 90 in endometrial carcinomas]
Endometrial Neoplasms
A study of heat shock protein 27 in endometrial carcinoma.
Endometrial Neoplasms
AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers.
Endometrial Neoplasms
Are IgG antibodies to heat shock proteins HSP27 and HSP60 useful markers in endometrial cancer and cervical cancer?
Endometrial Neoplasms
Autophagy in the physiological endometrium and cancer.
Endometrial Neoplasms
Bioluminescence Imaging to Monitor the Effects of the Hsp90 Inhibitor NVP-AUY922 on NF-?B Pathway in Endometrial Cancer.
Endometrial Neoplasms
Cell-free 27 kDa heat shock protein (hsp27) and hsp27-cytochrome c complexes in the cervix of women with ovarian or endometrial cancer.
Endometrial Neoplasms
Colocalization of estrogen and progesterone receptors with an estrogen-regulated heat shock protein in paraffin sections of human breast and endometrial cancer tissue.
Endometrial Neoplasms
Detection of the soluble heat shock protein 27 (hsp27) in human serum by an ELISA.
Endometrial Neoplasms
Endoplasmic reticulum stress is activated in endometrial adenocarcinoma.
Endometrial Neoplasms
Expression of heat shock proteins HSP70 and HSP90 in endometrial carcinomas. Correlation with clinicopathology, sex steroid receptor status, and p53 protein expression.
Endometrial Neoplasms
GRP78 induced by estrogen plays a role in the chemosensitivity of endometrial cancer.
Endometrial Neoplasms
GRP78 levels, regional fat distribution and endometrial cáncer.
Endometrial Neoplasms
GRP78 Mediates Cell Growth and Invasiveness in Endometrial Cancer.
Endometrial Neoplasms
High level of HSF1 associates with aggressive endometrial carcinoma and suggests potential for HSP90 inhibitors.
Endometrial Neoplasms
Identification of HSPA8 as a candidate biomarker for endometrial carcinoma by using iTRAQ-based proteomic analysis.
Endometrial Neoplasms
Immunological evidence for the identity between the hsp27 estrogen-regulated heat shock protein and the p29 estrogen receptor-associated protein in breast and endometrial cancer.
Endometrial Neoplasms
Intraperitoneal Fat through GRP78: A Risk Factor for Endometrial Cancer.
Endometrial Neoplasms
Life stress, negative mood states, and antibodies to heat shock protein 70 in endometrial cancer.
Endometrial Neoplasms
Over-expression of heat shock proteins in carcinogenic endometrium.
Endometrial Neoplasms
PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients.
Endometrial Neoplasms
PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma.
Endometrial Neoplasms
Prognostic significance of heat shock proteins HSP70 and HSP90 in endometrial carcinomas.
Endometrial Neoplasms
Proteomic analysis in endometrial cancer and endometrial hyperplasia tissues by 2D-DIGE technique.
Endometrial Neoplasms
RNAi Screening of the Glucose-Regulated Chaperones in Cancer with Self-Assembled siRNA Nanostructures.
Endometrial Neoplasms
Silencing of heat shock protein 70 expression enhances radiotherapy efficacy and inhibits cell invasion in endometrial cancer cell line.
Endometrial Neoplasms
The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival.
Endometrial Neoplasms
Utility and Mechanism of SHetA2 and Paclitaxel for Treatment of Endometrial Cancer.
Endometrial Neoplasms
[Expression and significance of heat shock protein 70, 90 in endometrial carcinomas]
Endometrial Neoplasms
[Expression of heat shock protein (HSP70) in normal endometrium and endometrial carcinomas]
Endometrial Neoplasms
[Heat shock proteins and malignancies of the female genital tract]
Endometriosis
An investigation of the effects of endometriosis on the proteome of human eutopic endometrium: a heterogeneous tissue with a complex disease.
Endometriosis
Cell-mediated immunity to human and Escherichia coli 60-kDa heat shock protein in women: association with a history of spontaneous abortion and endometriosis.
Endometriosis
Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy.
Endometriosis
Differential expression of genes in eutopic and ectopic endometrium from patients with ovarian endometriosis.
Endometriosis
Distribution of heat shock proteins in eutopic and ectopic endometrium in endometriosis and adenomyosis.
Endometriosis
Effect of GnRH agonist therapy on the expression of human heat shock protein 70 in eutopic and ectopic endometria of women with endometriosis.
Endometriosis
Expression of heat shock protein 70 kDa in human endometrium of normal and infertile women.
Endometriosis
Expression of the 60 kDa heat shock protein in peritoneal fluids from women with endometriosis: implications for endometriosis-associated infertility.
Endometriosis
Increased production of tumor necrosis factor-alpha by peritoneal fluid mononuclear cells induced by 60-kDa heat shock protein in women with minimal to mild endometriosis.
Endometriosis
Levels of oestrogen receptor, progesterone receptor and ?B-crystallin in eutopic endometrium in relation to pregnancy in women with endometriosis.
Endometriosis
Measurable serum markers of oxidative stress response in women with endometriosis.
Endometriosis
Proteolytic tailoring of the heat shock protein 70 and its implications in the pathogenesis of endometriosis.
Endometriosis
Serologic responses of infertile women to the 60-kd chlamydial heat shock protein (hsp60).
Endometriosis
Toll-like receptor 4-mediated growth of endometriosis by human heat-shock protein 70.
Endometriosis
[Inhibition effect and mechanisms of quercetin on surgically induced endometriosis]
Endometritis
Heat shock protein HSP90 immunoexpression in equine endometrium during oestrus, dioestrus and anoestrus.
Endophthalmitis
alphaB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis.
Endotoxemia
A single endotoxin challenge induces delayed myocardial protection against infarcation.
Endotoxemia
Cardiomyocyte-Specific Deficiency of HSPB1 Worsens Cardiac Dysfunction by Activating NF?B-Mediated Leukocyte Recruitment After Myocardial Infarction.
Endotoxemia
Effect of sodium arsenite on iNOS expression and vascular hyporeactivity associated with cecal ligation and puncture in the rat.
Endotoxemia
Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126.
Endotoxemia
Endotoxemia in the infant rats modulates HSP60 protein level in the pancreatic acinar cells.
Endotoxemia
Heat shock protein 70 confers cardiovascular protection during endotoxemia via inhibition of nuclear factor-kappaB activation and inducible nitric oxide synthase expression in the rostral ventrolateral medulla.
Endotoxemia
Heat shock protein suppresses the senescent lung cytokine response to acute endotoxemia.
Endotoxemia
In the rostral ventrolateral medulla, the 70-kDa heat shock protein (HSP70), but not HSP90, confers neuroprotection against fatal endotoxemia via augmentation of nitric-oxide synthase I (NOS I)/protein kinase G signaling pathway and inhibition of NOS II/peroxynitrite cascade.
Endotoxemia
Induction of heat shock protein 70 by zinc-bis-(DL-hydrogenaspartate) reduces cytokine liberation, apoptosis, and mortality rate in a rat model of LD100 endotoxemia.
Endotoxemia
Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia.
Endotoxemia
Long-lasting effect of infant rats endotoxemia on heat shock protein 60 in the pancreatic acinar cells: involvement of toll-like receptor 4.
Endotoxemia
The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia.
Enteritis
Mouse colitis induced by Escherichia coli producing Yersinia enterocolitica 60-kilodalton heat-shock protein: light and electron microscope study.
Ependymoma
Ependymoma Pediatric Brain Tumor Protein Fingerprinting by Integrated Mass Spectrometry Platforms: A Pilot Investigation.
Ependymoma
Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma.
Epidermolysis Bullosa Acquisita
Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid.
Epidermolysis Bullosa Acquisita
Autoantibodies to human stress proteins. A survey of various rheumatic and other inflammatory diseases.
Epidermolysis Bullosa Acquisita
Heat shock protein 90 inhibition: A potential double- or triple-edged sword in the treatment of mucous membrane pemphigoid.
Epidermolysis Bullosa Acquisita
Heat shock protein 90 is required for ex vivo neutrophil-driven autoantibody-induced tissue damage in experimental epidermolysis bullosa acquisita.
Epidermolysis Bullosa Acquisita
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Epidermolysis Bullosa Acquisita
Heat-shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that nonmalignant plasma cells are not therapeutic targets.
Epidermolysis Bullosa Acquisita
Immunomodulatory effects of heat shock protein 90 inhibition on humoral immune responses.
Epidermolysis Bullosa Acquisita
Topically Applied Hsp90 Blocker 17AAG Inhibits Autoantibody-Mediated Blister-Inducing Cutaneous Inflammation.
Epilepsy
Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy.
Epilepsy
Blood biomarkers predictive of epilepsy after an acute stroke event.
Epilepsy
CDDO-Me Attenuates Astroglial Autophagy via Nrf2-, ERK1/2-SP1- and Src-CK2-PTEN-PI3K/AKT-Mediated Signaling Pathways in the Hippocampus of Chronic Epilepsy Rats.
Epilepsy
Cognitive Function and Heat Shock Protein 70 in Children With Temporal Lobe Epilepsy.
Epilepsy
Correlation between seizure intensity and stress protein expression after limbic epilepsy in the rat brain.
Epilepsy
Elevated interictal serum HSP-70 levels as an indicator of neurodegeneration for chronic migraine.
Epilepsy
Epilepsy: HSP90 inhibition suppresses seizures.
Epilepsy
Heat shock protein 70 expression in epilepsy suggests stress rather than protection.
Epilepsy
Heat shock proteins and neuroprotection.
Epilepsy
Hippocampal expression of heat shock proteins in mesial temporal lobe epilepsy with psychiatric comorbidities and their relation to seizure outcome.
Epilepsy
Hsp60 response in experimental and human temporal lobe epilepsy.
Epilepsy
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Epilepsy
Hsp90? inhibitors prevent GLT-1 degradation but have no beneficial efficacy on absence epilepsy.
Epilepsy
Inhibition of Hsp70 Suppresses Neuronal Hyperexcitability and Attenuates Epilepsy by Enhancing A-Type Potassium Current.
Epilepsy
miR-16-1 expression, heat shock protein 70 and inflammatory reactions in astrocytes of mice with epilepsy induced by encephalitis B virus infection.
Epilepsy
Molecular alterations of the TLR4-signaling cascade in canine epilepsy.
Epilepsy
Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy.
Epilepsy
Systematic identification of the HSP90 regulated proteome.
Epilepsy
The neuroprotective potential of heat shock protein 70 (HSP70).
Epilepsy, Reflex
[Effects of thermal preconditioning on convulsive activity in rats with inheritable form of audiogenic epilepsy].
Epilepsy, Temporal Lobe
Cognitive Function and Heat Shock Protein 70 in Children With Temporal Lobe Epilepsy.
Epilepsy, Temporal Lobe
Hsp60 response in experimental and human temporal lobe epilepsy.
Epilepsy, Temporal Lobe
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Epilepsy, Temporal Lobe
Inhibition of Hsp70 Suppresses Neuronal Hyperexcitability and Attenuates Epilepsy by Enhancing A-Type Potassium Current.
Epiretinal Membrane
Heat Shock Protein 90 Involvement in the Development of Idiopathic Epiretinal Membranes.
Epstein-Barr Virus Infections
Epstein-Barr virus upregulates phosphorylated heat shock protein 27 kDa in carcinoma cells using the phosphoinositide 3-kinase/Akt pathway.
Epstein-Barr Virus Infections
Heat shock protein 90 expression in Epstein-Barr virus-infected B cells promotes gammadelta T-cell proliferation in vitro.
Epstein-Barr Virus Infections
Identification of tumor necrosis factor signaling-related proteins during Epstein-Barr virus-induced B cell transformation.
Erectile Dysfunction
Heat shock protein 9-mediated inflammation reaction in patients with chronic prostatitis with erectile dysfunction.
Erythema
IgM anti-phenolic glycolipid I and IgG anti-10-kDa heat shock protein antibodies in sera and immune complexes isolated from leprosy patients with or without erythema nodosum leprosum and contacts.
Erythema
Non-invasive detection of local tissue responses to predict pressure ulcer development in mouse models.
Erythema
Prevention of the ultraviolet effects on clinical and histopathological changes, as well as the heat shock protein-70 expression in mouse skin by topical application of algal UV-absorbing compounds.
Erythema Nodosum
IgM anti-phenolic glycolipid I and IgG anti-10-kDa heat shock protein antibodies in sera and immune complexes isolated from leprosy patients with or without erythema nodosum leprosum and contacts.
Esophageal Neoplasms
Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer.
Esophageal Neoplasms
Changes in the localization of heat shock protein 72 correlated with development of thermotolerance in human esophageal cancer cell line.
Esophageal Neoplasms
Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells.
Esophageal Neoplasms
Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells.
Esophageal Neoplasms
Esophageal cancer alters the expression of nuclear pore complex binding protein Hsc70 and eIF5A-1.
Esophageal Neoplasms
Exogenous H2S promotes cancer progression by activating JAK2/STAT3 signaling pathway in esophageal EC109 cells.
Esophageal Neoplasms
Heat shock protein 105 peptide vaccine could induce antitumor immune reactions in a phase I clinical trial.
Esophageal Neoplasms
Identification of HLA-A2 or HLA-A24-restricted CTL epitopes for potential HSP105-targeted immunotherapy in colorectal cancer.
Esophageal Neoplasms
Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.
Esophageal Neoplasms
Novel immunohistochemical monoclonal antibody against human glucose-regulated protein 78.
Esophageal Neoplasms
PKC? counteracts oxidative stress by regulating Hsc70 in an esophageal cancer cell line.
Esophageal Neoplasms
Prognostic significance of heat shock protein 110 expression and T lymphocyte infiltration in esophageal cancer.
Esophageal Neoplasms
Tumor Immune Systems in Esophageal Cancer with Special Reference to Heat-shock Protein 70 and Humoral Immunity.
Esophageal Neoplasms
[Screening of differentially expressed proteins from human esophageal cancer and esophageal tissues by two-dimensional difference gel electrophoresis and mass spectrometry]
Esophageal Squamous Cell Carcinoma
BIIB021, a novel Hsp90 inhibitor, sensitizes esophageal squamous cell carcinoma to radiation.
Esophageal Squamous Cell Carcinoma
Clinical Significance of Monitoring Circulating Free DNA and Plasma Heat Shock Protein 90alpha in Patients with Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
Clinical significance of serum dynamics of HSP90a level in esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy.
Esophageal Squamous Cell Carcinoma
Correlation between clinicopathology and expression of heat shock protein 72 and glycoprotein 96 in human esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Expression of heat shock protein 70 in grossly resected esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Expression of heat-shock protein Hsp60 correlated with the apoptotic index and patient prognosis in human oesophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Expression patterns of aurora kinase B, heat shock protein 47, and periostin in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Heat shock protein family B member 1 facilitates ezrin activation to control cell migration in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
High Expression of GRP78 Promotes Invasion and Metastases in Patients with Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
HSP90 Inhibitor Ganetespib (STA-9090) Inhibits Tumor Growth in c-Myc-Dependent Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
MicroRNA-27a downregulates the expression of Hsp90 and enhances the radiosensitivity in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Overexpression of 27-kDa heat shock protein relates to poor histological differentiation in human oesophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Proteomics-based identification of autoantibody against heat shock protein 70 as a diagnostic marker in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Silence of HDAC6 suppressed esophageal squamous cell carcinoma proliferation and migration by disrupting chaperone function of HSP90.
Esophageal Squamous Cell Carcinoma
SUMOylation of HSP27 regulates PKM2 to promote esophageal squamous cell carcinoma progression.
Esophageal Squamous Cell Carcinoma
Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells.
Esophageal Squamous Cell Carcinoma
The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
Esophageal Squamous Cell Carcinoma
[Expression and significance of heat shock proteins in esophageal squamous cell carcinoma]
Esophagitis
Analysis of mucosal stress response in acid-induced esophagitis in opossum.
Esophagitis
Expression of heat shock protein 27 in the esophageal tissue of rats with reflux esophagitis.
Esophagitis, Peptic
Expression of heat shock protein 27 in the esophageal tissue of rats with reflux esophagitis.
Esophagitis, Peptic
Specific induction of a 72-kDa heat shock protein protects esophageal mucosa from reflux esophagitis.
Essential Hypertension
Expression of Heat Shock Protein 70 Gene and Its Correlation with Inflammatory Markers in Essential Hypertension.
Essential Hypertension
Induction of heat shock protein 72 protects against organ damage in essential hypertension: A hypothesis.
Essential Hypertension
The role of autoimmune reactivity induced by heat shock protein 70 in the pathogenesis of essential hypertension.
Esthesioneuroblastoma, Olfactory
Expression patterns of Trk-A, Trk-B, GRP78, and p75NRT in olfactory neuroblastoma.
Exanthema
Prediction of an Epitope-based Computational Vaccine Strategy for Gaining Concurrent Immunization Against the Venom Proteins of Australian Box Jellyfish.
Exfoliation Syndrome
Aqueous humor heat-shock protein 70, periostin, and irisin levels in patients with pseudoexfoliation syndrome.
Exfoliation Syndrome
Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma.
Eye Diseases
First-in-Human Phase I Study of an Oral HSP90 Inhibitor, TAS-116, in Patients with Advanced Solid Tumors.
Fallopian Tube Diseases
Serum interleukin-1?, interleukin-8 and anti-heat shock 60 Chlamydia trachomatis antibodies as markers of ectopic pregnancy.
Fanconi Anemia
Hsp90 and the Fanconi anemia pathway: a molecular link between protein quality control and the DNA damage response.
Fanconi Anemia
Hsp90 regulates the Fanconi anemia DNA damage response pathway.
Fanconi Anemia
Molecular chaperone GRP94 binds to the Fanconi anemia group C protein and regulates its intracellular expression.
Fanconi Anemia
Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.
Fanconi Syndrome
Na+,K(+)-ATPase expression in maleic-acid-induced Fanconi syndrome in rats.
Fatigue Syndrome, Chronic
Differential heat shock protein responses to strenuous standardized exercise in chronic fatigue syndrome patients and matched healthy controls.
Fatty Liver
CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy.
Fatty Liver
GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Fatty Liver
Inhibition of HSP90? Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System.
Fatty Liver
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice.
Fatty Liver
Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice.
Fatty Liver
The ménage à trois of autophagy, lipid droplets and liver disease.
Fatty Liver, Alcoholic
Changes in tumor necrosis factor-?, heat shock protein 70, malondialdehyde, and superoxide dismutase in patients with different severities of alcoholic fatty liver disease: a prospective observational study.
Fetal Growth Retardation
Assessment of placental and maternal stress responses in patients with pregnancy related complications via monitoring of heat shock protein mRNA levels.
Fetal Growth Retardation
Decreased expression of phosphorylated placental heat shock protein 27 in human and ovine intrauterine growth restriction (IUGR).
Fetal Growth Retardation
Enhancement of heat shock protein 70 attenuates inducible nitric oxide synthase in preeclampsia complicated with fetal growth restriction.
Fetal Growth Retardation
Heat Shock Protein 70 Expression is Increased in the Liver of Neonatal Intrauterine Growth Retardation Piglets.
Fetal Growth Retardation
Heat shock protein 70 is upregulated in the intestine of intrauterine growth retardation piglets.
Fetal Growth Retardation
Heat shock proteins and heat shock protein-antibody complexes in placental tissues.
Fetal Growth Retardation
Impairment of cellular immunity is associated with overexpression of heat shock protein 70 in neonatal pigs with intrauterine growth retardation.
Fetal Hypoxia
Assessment of placental and maternal stress responses in patients with pregnancy related complications via monitoring of heat shock protein mRNA levels.
Fetal Membranes, Premature Rupture
Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes.
Fibroma
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Fibroma
Oral lichen planus: an immunohistochemical study of heat shock proteins (HSPs) and cytokeratins (CKs) and a unifying hypothesis of pathogenesis.
Fibromatosis, Gingival
Effect of transforming growth factor-beta1, interleukin-6, and interferon-gamma on the expression of type I collagen, heat shock protein 47, matrix metalloproteinase (MMP)-1 and MMP-2 by fibroblasts from normal gingiva and hereditary gingival fibromatosis.
Fibromatosis, Gingival
Immunoexpression of ?2-integrin and Hsp47 in hereditary gingival fibromatosis and gingival fibromatosis-associated dental abnormalities.
Fibromyalgia
(220) Associations between heat shock protein and symptom burden in Fibromyalgia Syndrome (FMS).
Fibrosarcoma
A 2,5-Dihydroxybenzoic Acid-Gelatin Conjugate Inhibits the Basal and Hsp90-Stimulated Migration and Invasion of Tumor Cells.
Fibrosarcoma
Actinopyrone D, a new downregulator of the molecular chaperone GRP78 from Streptomyces sp.
Fibrosarcoma
Autoreactive and heat shock protein 60-recognizing CD4+ T-cells show antitumor activity against syngeneic fibrosarcoma.
Fibrosarcoma
Cell surface heparan sulfate proteoglycans are involved in the binding of Hsp90? and Hsp90? to the cell plasma membrane.
Fibrosarcoma
Cell surface heparan sulfate proteoglycans are involved in the extracellular Hsp90-stimulated migration and invasion of cancer cells.
Fibrosarcoma
Effect of heat shock protein 90 (Hsp90) on migration and invasion of human cancer cells in vitro.
Fibrosarcoma
Efrapeptin J, a new down-regulator of the molecular chaperone GRP78 from a marine Tolypocladium sp.
Fibrosarcoma
Expression of the 72-kD heat shock protein is induced by ultraviolet A radiation in a human fibrosarcoma cell line.
Fibrosarcoma
Extracellular roles for the molecular chaperone, hsp90.
Fibrosarcoma
Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness.
Fibrosarcoma
HSP60 is transported through the secretory pathway of 3-MCA-induced fibrosarcoma tumour cells and undergoes N-glycosylation.
Fibrosarcoma
Induction of Hsp60 by Photofrin-mediated photodynamic therapy.
Fibrosarcoma
Induction of plasminogen activator inhibitor 1 biosynthesis by hyperthermia.
Fibrosarcoma
Involvement of peptide antigens in the cytotoxicity between 70-kDa heat shock cognate protein-like molecule and CD3+, CD4-, CD8-, TCR-alpha beta- killer T cells.
Fibrosarcoma
Novel GRP78 Molecular Chaperone Expression Down-regulators JBIR-04 and -05 Isolated from Streptomyces violaceoniger.
Fibrosarcoma
Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase.
Fibrosarcoma
Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model.
Fibrosarcoma
Prunustatin A, a novel GRP78 molecular chaperone down-regulator isolated from Streptomyces violaceoniger.
Fibrosarcoma
The Broad Stroke of Hsp90 Inhibitors: Painting over the RAF Inhibitor Paradox.
Fibrosarcoma
The characterization of exosomes from fibrosarcoma cell and the useful usage of Dynamic Light Scattering (DLS) for their evaluation.
Fibrosarcoma
The effect of vaccination with the lysate of heat-shocked tumor cells on nitric oxide production in BALB/c mice with fibrosarcoma tumor.
Fibrosarcoma
Use of the glucose starvation-inducible glucose-regulated protein 78 promoter in suicide gene therapy of murine fibrosarcoma.
Fibrosarcoma
Use of the stress-inducible grp78/BiP promoter in targeting high level gene expression in fibrosarcoma in vivo.
Fibrosarcoma
[The Role of Membrane-Bound Heat Shock Proteins Hsp90 in Migration of Tumor Cells in vitro and Involvement of Cell Surface Heparan Sulfate Proteoglycans in Protein Binding to Plasma Membrane].
Filariasis
Heat shock cognate 70 is a prominent immunogen in Brugian filariasis.
Filariasis
Sequencing of the complete gene coding for the GroEL of the Wolbachia of Dirofilaria immitis and expression and purification of the recombinant protein.
Flavivirus Infections
Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling.
Fluorosis, Dental
[Effect of fluoride on the expression of endoplasmic reticulum chaperone in ameloblast of rat incisor].
Follicular Cyst
Levels of heat shock protein transcripts in normal follicles and ovarian follicular cysts.
Foodborne Diseases
Glucose-regulated protein 75 in foodborne disease models induces renal tubular necrosis.
Foot Ulcer
Heat Shock Protein 70 Gene Single Nucleotide Polymorphism and Diabetic Foot Ulcer. Is There Any Relationship?
Foot Ulcer
Heat-shock protein 70 gene polymorphism is associated with the severity of diabetic foot ulcer and the outcome of surgical treatment.
Foot-and-Mouth Disease
The Cellular Chaperone Heat Shock Protein 90 Is Required for Foot-and-Mouth Disease Virus Capsid Precursor Processing and Assembly of Capsid Pentamers.
Friedreich Ataxia
A role for astrocytes in cerebellar deficits in frataxin deficiency: Protection by insulin-like growth factor I.
Friedreich Ataxia
GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich Ataxia cellular models.
Frontotemporal Dementia
Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins.
Frontotemporal Dementia
Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.
Frontotemporal Dementia
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Frontotemporal Lobar Degeneration
Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
Frontotemporal Lobar Degeneration
Phosphoproteomic Analysis Reveals Site-Specific Changes in GFAP and NDRG2 Phosphorylation in Frontotemporal Lobar Degeneration.
Fuchs' Endothelial Dystrophy
Unfolded protein response in fuchs endothelial corneal dystrophy: a unifying pathogenic pathway?
Gallbladder Neoplasms
Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
Gastritis
An increased number of gamma/delta T-cells and gastric epithelial cell expression of the groEL stress-protein homologue in Helicobacter pylori-associated chronic gastritis of the antrum.
Gastritis
Autoantibodies to a specific peptide epitope of human Hsp60 (ATVLA) with homology to Helicobacter pylori HspB in H. pylori-infected patients.
Gastritis
Circulating antibodies to the 60-kD heat shock protein (hsp) family in patients with Helicobacter pylori infection.
Gastritis
Clarithromycin increases the release of heat shock protein B from Helicobacter pylori.
Gastritis
Combined Extracts of
Gastritis
Effect of bacterial flora on postimmunization gastritis following oral vaccination of mice with Helicobacter pylori heat shock protein 60.
Gastritis
Expression of heat shock protein 90 beta in human gastric cancer tissue and SGC7901/VCR of MDR-type gastric cancer cell line.
Gastritis
Helicobacter pylori heat shock protein 60 mediates interleukin-6 production by macrophages via a toll-like receptor (TLR)-2-, TLR-4-, and myeloid differentiation factor 88-independent mechanism.
Gastritis
Immune response in Helicobacter pylori-induced low-grade gastric-mucosa-associated lymphoid tissue (MALT) lymphoma.
Gastritis
Seropositivity to Helicobacter pylori heat shock protein 60 is strongly associated with intensity of chronic inflammation, particularly in antrum mucosa: an extension of an 18-year follow-up study of chronic gastritis in Saaremaa, Estonia.
Gastritis
Significance of expression of heat shock protein90alpha in human gastric cancer.
Gastritis
Suppressive effects of DNA vaccines encoding heat shock protein on Helicobacter pylori-induced gastritis in mice.
Gastritis
[Relationship between Pi-Wei damp-heat syndrome with expressions of nuclear factor-kappaBmRNA and heat shock protein 70 mRNA in patients with chronic gastritis]
Gastritis, Atrophic
Heat Shock Protein 27 Expression is Inversely Correlated with Atrophic Gastritis and Intraepithelial Neoplasia.
Gastritis, Atrophic
[Effect of Chinese drugs for strengthening Pi, harmonizing Wei, and dispersing blood stasis on the expression of gastric mucosal heat shock protein 70 in chronic atrophic gastritis patients].
Gastroesophageal Reflux
Use of oesophageal stress response proteins as potential biomarkers in the screening for Barrett's oesophagus.
Gastrointestinal Diseases
Diagnostic, clinicopathologic, therapeutic and prognostic value of Plasma Heat Shock Protein 90 levels in patients with advanced Gastrointestinal Carcinoma.
Gastrointestinal Neoplasms
A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial.
Gastrointestinal Neoplasms
Diagnostic, clinicopathologic, therapeutic and prognostic value of Plasma Heat Shock Protein 90 levels in patients with advanced Gastrointestinal Carcinoma.
Gastrointestinal Neoplasms
Heat shock proteins are differentially expressed in human gastrointestinal cancers.
Gastrointestinal Neoplasms
Heat-shock protein 90 (Hsp90) as a molecular target for therapy of gastrointestinal cancer.
Gastrointestinal Neoplasms
Mortalin/glucose-regulated protein 75 promotes the cisplatin-resistance of gastric cancer via regulating anti-oxidation/apoptosis and metabolic reprogramming.
Gastrointestinal Stromal Tumors
A phase 1 study of the heat shock protein 90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft tissue sarcomas.
Gastrointestinal Stromal Tumors
A Phase 2 Study of the Hsp90 Inhibitor AUY922 as Treatment for Patients with Refractory Gastrointestinal Stromal Tumors.
Gastrointestinal Stromal Tumors
An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.
Gastrointestinal Stromal Tumors
Dose-escalation study of a second-generation non-ansamycin HSP90 inhibitor, onalespib (AT13387), in combination with imatinib in patients with metastatic gastrointestinal stromal tumour.
Gastrointestinal Stromal Tumors
Efficacy and safety of TAS-116, an oral inhibitor of heat shock protein 90, in patients with metastatic or unresectable gastrointestinal stromal tumour refractory to imatinib, sunitinib and regorafenib: a phase II, single-arm trial.
Gastrointestinal Stromal Tumors
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Gastrointestinal Stromal Tumors
Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor.
Gastrointestinal Stromal Tumors
Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.
Gastrointestinal Stromal Tumors
Heat Shock Proteins: A Potential Anticancer Target.
Gastrointestinal Stromal Tumors
Inhibitors of deacetylases suppress oncogenic KIT signaling, acetylate HSP90, and induce apoptosis in gastrointestinal stromal tumors.
Gastrointestinal Stromal Tumors
STI571 (Glivec) inhibits the interaction between c-KIT and heat shock protein 90 of the gastrointestinal stromal tumor cell line, GIST-T1.
Gastrointestinal Stromal Tumors
The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage and cell proliferation arrest in xenografts models of gastrointestinal stromal tumors.
Gastrointestinal Stromal Tumors
The HSP90 Inhibitor, AT13387, Is Effective against Imatinib-Sensitive and -Resistant Gastrointestinal Stromal Tumor Models.
Gastrointestinal Stromal Tumors
[2 + 2 + 2] Cyclotrimerization with Propargyl Halides as Copartners: Formal Total Synthesis of the Antitumor Hsp90 Inhibitor AT13387.
Gaucher Disease
Brain-penetrant heat shock protein amplifier arimoclomol enhances GCase activity in in vitro Gaucher disease models.
Gaucher Disease
Histone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperones.
Gaucher Disease
Mutant glucocerebrosidase in Gaucher disease recruits Hsp27 to the Hsp90 chaperone complex for proteasomal degradation.
Gaucher Disease
Treatment perspectives for the lysosomal storage diseases.
Genetic Diseases, Inborn
Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter.
Genetic Diseases, Inborn
Histone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperones.
Genetic Diseases, Inborn
HSP90 Shapes the Consequences of Human Genetic Variation.
Genetic Diseases, Inborn
Molecular chaperones: small heat shock proteins in the limelight.
Giant Cell Arteritis
Serum levels of antibodies to Chlamydia pneumoniae and human HSP60 in giant cell arteritis patients.
Giardiasis
Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.
Gingival Diseases
PCR array analysis identified hyperproliferation but not autophagy or apoptosis in fibrous epulis.
Gingival Diseases
Serum antibodies to Porphyromonas gingivalis chaperone HtpG predict health in periodontitis susceptible patients.
Gingivitis
IgG class, but not IgA or IgM, antibodies to peptides of the Porphyromonas gingivalis chaperone HtpG predict health in periodontitis using a fluorescent ELISA.
Gingivitis
Salivary anti-hsp65 antibodies as a diagnostic marker for gingivitis and a possible link to atherosclerosis.
Gingivitis
Serum antibodies to Porphyromonas gingivalis chaperone HtpG predict health in periodontitis susceptible patients.
Gingivitis
Up-regulation of the endoplasmic reticulum stress-response in periodontal disease.
Glanders
Detection of the host immune response to Burkholderia mallei heat-shock proteins GroEL and DnaK in a glanders patient and infected mice.
Glanders
Development of a microsphere-based immunoassay for the serological detection of glanders in equids.
Glanders
Identification of a new diagnostic antigen for glanders using immunoproteome analysis.
Glaucoma
Amino acid regions 357-368 and 418-427 of Streptococcus pyogenes 60kDa heat shock protein are recognized by antibodies from glaucomatous patient sera.
Glaucoma
Anti-Ro/SS-A positivity and heat shock protein antibodies in patients with normal-pressure glaucoma.
Glaucoma
Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor.
Glaucoma
Aqueous humor heat-shock protein 70, periostin, and irisin levels in patients with pseudoexfoliation syndrome.
Glaucoma
Association between open-angle glaucoma and gene polymorphism for heat-shock protein 70-1.
Glaucoma
Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts.
Glaucoma
Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms.
Glaucoma
Complex antibody profile changes in an experimental autoimmune glaucoma animal model.
Glaucoma
Down-regulation of GRP78 in human glaucomatous trabecular meshwork cells.
Glaucoma
Engineered superparamagnetic Mn(0.5)Zn(0.5)Fe(2)O(4) nanoparticles as a heat shock protein induction agent for ocular neuroprotection in glaucoma.
Glaucoma
Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma.
Glaucoma
Evaluation of heat shock protein (HSP-72) expression in retinal ganglion cells of rats with glaucoma.
Glaucoma
Heat shock protein 72 protects retinal ganglion cells in rat model of acute glaucoma.
Glaucoma
Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye.
Glaucoma
Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand.
Glaucoma
Induction of heat shock protein 72 in RGCs of rat acute glaucoma model after heat stress or zinc administration.
Glaucoma
Induction of heat shock protein 72 protects retinal ganglion cells in a rat glaucoma model.
Glaucoma
Levels of antibodies against human heat shock protein (HSP) 60 in patients with glaucoma in Poland.
Glaucoma
Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma model.
Glaucoma
S100 Alone Has the Same Destructive Effect on Retinal Ganglion Cells as in Combination with HSP 27 in an Autoimmune Glaucoma Model.
Glaucoma
Sensitized heat shock protein 27 induces retinal ganglion cells apoptosis in rat glaucoma model.
Glaucoma
Serum autoantibodies to heat shock proteins in glaucoma patients from Japan and the United States.
Glaucoma
The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma model.
Glaucoma
The Small Heat Shock Protein ?-Crystallin B Shows Neuroprotective Properties in a Glaucoma Animal Model.
Glaucoma
[The expression of heat shock protein 27 in retinal ganglion cells in the rat glaucoma model.]
Glaucoma
[The GG genotype of the HSPA1B gene is associated with increased risk of glaucoma in northern Iran].
Glaucoma, Angle-Closure
HSP70 expression before and after treatment and its clinical value in patients with acute angle-closure glaucoma.
Glaucoma, Open-Angle
Anti-Ro/SS-A positivity and heat shock protein antibodies in patients with normal-pressure glaucoma.
Glaucoma, Open-Angle
Association between open-angle glaucoma and gene polymorphism for heat-shock protein 70-1.
Glaucoma, Open-Angle
Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts.
Glaucoma, Open-Angle
BDNF and HSP gene polymorphisms and their influence on the progression of primary open-angle glaucoma in a Polish population.
Glaucoma, Open-Angle
Discovery of a Potent Grp94 Selective Inhibitor with Anti-Inflammatory Efficacy in a Mouse Model of Ulcerative Colitis.
Glaucoma, Open-Angle
Down-regulation of GRP78 in human glaucomatous trabecular meshwork cells.
Glaucoma, Open-Angle
Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma.
Glioblastoma
17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.
Glioblastoma
A 2,5-Dihydroxybenzoic Acid-Gelatin Conjugate Inhibits the Basal and Hsp90-Stimulated Migration and Invasion of Tumor Cells.
Glioblastoma
A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation.
Glioblastoma
A Novel Extracellular Hsp90 Mediated Co-Receptor Function for LRP1 Regulates EphA2 Dependent Glioblastoma Cell Invasion.
Glioblastoma
Acquired resistance to 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) in glioblastoma cells.
Glioblastoma
Aldehyde dehydrogenase and HSP90 co-localize in human glioblastoma biopsy cells.
Glioblastoma
Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non-Small Cell Lung Cancer Cell Lines and Tumor Models.
Glioblastoma
Association of elevated GRP78 expression with increased astrocytoma malignancy via Akt and ERK pathways.
Glioblastoma
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Glioblastoma
Autologous Heat Shock Protein Peptide Vaccination for Newly Diagnosed Glioblastoma: Impact of Peripheral PD-L1 Expression on Response to Therapy.
Glioblastoma
Biomarker discovery: a proteomic approach for brain cancer profiling.
Glioblastoma
Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors.
Glioblastoma
Calreticulin, a Molecular Chaperone in the Endoplasmic Reticulum, Modulates Radiosensitivity of Human Glioblastoma U251MG Cells.
Glioblastoma
Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells.
Glioblastoma
Cell surface GRP78 as a biomarker and target for suppressing glioma cells.
Glioblastoma
Cell surface heparan sulfate proteoglycans are involved in the binding of Hsp90? and Hsp90? to the cell plasma membrane.
Glioblastoma
Cell surface heparan sulfate proteoglycans are involved in the extracellular Hsp90-stimulated migration and invasion of cancer cells.
Glioblastoma
Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.
Glioblastoma
Chaperonins in cancer: Expression, function, and migration in extracellular vesicles.
Glioblastoma
Characterizing Cell Stress and GRP78 in Glioma to Enhance Tumor Treatment.
Glioblastoma
CTL responses to HSP47 associated with the prolonged survival of patients with glioblastomas.
Glioblastoma
Cytoplasmic sequestration of the tumor suppressor p53 by a heat shock protein 70 family member, mortalin, in human colorectal adenocarcinoma cell lines.
Glioblastoma
Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway.
Glioblastoma
Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
Glioblastoma
Effect of heat shock protein 90 (Hsp90) on migration and invasion of human cancer cells in vitro.
Glioblastoma
Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70.
Glioblastoma
Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas.
Glioblastoma
ER calcium discharge stimulates GDNF gene expression through MAPK-dependent and -independent pathways in rat C6 glioblastoma cells.
Glioblastoma
Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung Cancer.
Glioblastoma
Expression and functional activity of heat shock proteins in human glioblastoma multiforme.
Glioblastoma
Expression of heme oxygenase isozyme mRNAs in the human brain and induction of heme oxygenase-1 by nitric oxide donors.
Glioblastoma
Expression of the small heat shock protein (hsp) 27 in human astrocytomas correlates with histologic grades and tumor growth fractions.
Glioblastoma
Geldanamycin-induced degradation of Chk1 is mediated by proteasome.
Glioblastoma
Global targeting of subcellular heat shock protein-90 networks for therapy of glioblastoma.
Glioblastoma
Glucose-regulated protein 78 substrate-binding domain alters its conformation upon EGCG inhibitor binding to nucleotide-binding domain: Molecular dynamics studies.
Glioblastoma
Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
Glioblastoma
GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death.
Glioblastoma
GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis.
Glioblastoma
GRP78-targeted in-silico virtual screening of novel anticancer agents.
Glioblastoma
Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells.
Glioblastoma
Heat shock protein 72 expression allows permissive replication of oncolytic adenovirus dl1520 (ONYX-015) in rat glioblastoma cells.
Glioblastoma
Heat shock protein expression in human gliomas.
Glioblastoma
Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccination for Recurrent Glioblastoma: A Phase II, Single Arm Trial.
Glioblastoma
Heat shock protein peptide complex-96 vaccination for newly diagnosed glioblastoma: a phase I, single-arm trial.
Glioblastoma
Heat shock protein vaccines against glioblastoma: from bench to bedside.
Glioblastoma
Heat shock proteins in glioblastomas.
Glioblastoma
Heat shock transcription factor, HSF, is activated by ultraviolet irradiation.
Glioblastoma
HSP27 knockdown produces synergistic induction of apoptosis by HSP90 and kinase inhibitors in glioblastoma multiforme.
Glioblastoma
Hsp90 inhibition by NVP-AUY922 and NVP-BEP800 decreases migration and invasion of irradiated normoxic and hypoxic tumor cell lines.
Glioblastoma
Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma.
Glioblastoma
Hsp90 inhibitor NMS-E973 exerts the anticancer effect against glioblastoma via induction of PUMA-mediated apoptosis.
Glioblastoma
Immunoexpression patterns for Hypoxia-inducible Factor-1? and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
Glioblastoma
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990.
Glioblastoma
Induction of radiation resistance by a heat shock protein inhibitor, KNK437, in human glioblastoma cells.
Glioblastoma
Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
Glioblastoma
Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond.
Glioblastoma
Inhibition of Hsp90 function by ansamycins causes downregulation of cdc2 and cdc25c and G(2)/M arrest in glioblastoma cell lines.
Glioblastoma
Inhibition of nestin suppresses stem cell phenotype of glioblastomas through the alteration of post-translational modification of heat shock protein HSPA8/HSC71.
Glioblastoma
Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII.
Glioblastoma
Irradiation facilitates the inhibitory effect of the heat shock protein 90 inhibitor NVP-BEP800 on the proliferation of malignant glioblastoma cells through attenuation of the upregulation of heat shock protein 70.
Glioblastoma
Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type.
Glioblastoma
Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma.
Glioblastoma
MEK-inhibitor PD184352 enhances the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922: the role of cell type and drug-irradiation schedule.
Glioblastoma
Membrane Hsp70-supported cell-to-cell connections via tunneling nanotubes revealed by live-cell STED nanoscopy.
Glioblastoma
Overexpression of cytosolic, plasma membrane bound and extracellular heat shock protein 70 (Hsp70) in primary glioblastomas.
Glioblastoma
Photo-immune therapy with liposomally formulated phospholipid-conjugated indocyanine green induces specific antitumor responses with heat shock protein-70 expression in a glioblastoma model.
Glioblastoma
Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.
Glioblastoma
Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and Neuroblastoma Cells.
Glioblastoma
Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma.
Glioblastoma
Retinoic acid-induced apoptotic pathway in T-cell lymphoma: Identification of four groups of genes with differential biological functions.
Glioblastoma
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway.
Glioblastoma
Stimulation of Electroporation-Induced Inward Currents in Glioblastoma Cell Lines by the Heat Shock Protein Inhibitor AUY922.
Glioblastoma
Suppression of heat-induced HSF activation by CDDP in human glioblastoma cells.
Glioblastoma
T cell receptor repertoire as a prognosis marker for heat shock protein peptide complex-96 vaccine trial against newly diagnosed glioblastoma.
Glioblastoma
Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA.
Glioblastoma
The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme.
Glioblastoma
The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.
Glioblastoma
The protein kinase inhibitor, H-7, suppresses heat induced activation of heat shock transcription factor 1.
Glioblastoma
The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.
Glioblastoma
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
Glioblastoma
Transactivation of the epidermal growth factor receptor by heat shock protein 90 via Toll-like receptor 4 contributes to the migration of glioblastoma cells.
Glioblastoma
UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT.
Glioblastoma
Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.
Glioblastoma
[The Role of Membrane-Bound Heat Shock Proteins Hsp90 in Migration of Tumor Cells in vitro and Involvement of Cell Surface Heparan Sulfate Proteoglycans in Protein Binding to Plasma Membrane].
Glioma
70-kDa heat shock protein coated magnetic nanocarriers as a nanovaccine for induction of anti-tumor immune response in experimental glioma.
Glioma
A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea.
Glioma
A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.
Glioma
A novel therapeutic strategy for the treatment of glioma, combining chemical and molecular targeting of hsp90a.
Glioma
Abrogation of mitogen-activated protein kinase and Akt signaling by vandetanib synergistically potentiates histone deacetylase inhibitor-induced apoptosis in human glioma cells.
Glioma
Acidosis acts through HSP90 in a PHD/VHL-independent manner to promote HIF function and stem cell maintenance in glioma.
Glioma
All-stage precisional glioma targeted therapy enabled by a well-designed D-peptide.
Glioma
Alpha2 adrenoreceptor agonist regulates protein kinase C-induced heat shock protein 27 phosphorylation in C6 glioma cells.
Glioma
Association between small heat shock protein B11 and the prognostic value of MGMT promoter methylation in patients with high-grade glioma.
Glioma
Association of elevated GRP78 expression with increased astrocytoma malignancy via Akt and ERK pathways.
Glioma
Augmentation of MHC class I antigen presentation via heat shock protein expression by hyperthermia.
Glioma
Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma.
Glioma
Can The Lack of HSP90alpha Protein in Brain Normal Tissue and Cell Lines, Rationalise it as a Possible Therapeutic Target for Gliomas?
Glioma
Cell surface GRP78 as a biomarker and target for suppressing glioma cells.
Glioma
Cell surface GRP78 regulates BACE2 via lysosome-dependent manner to maintain mesenchymal phenotype of glioma stem cells.
Glioma
Characterization of promoter elements mediating ethanol regulation of hsc70 gene transcription.
Glioma
Characterizing Cell Stress and GRP78 in Glioma to Enhance Tumor Treatment.
Glioma
Cooperative inhibitory effect of ZD1839 (Iressa) in combination with 17-AAG on glioma cell growth.
Glioma
Could the Anti-Chaperone VER155008 Replace Temozolomide for Glioma Treatment.
Glioma
Deletion of the SPARC acidic domain or EGF-like module reduces SPARC-induced migration and signaling through p38 MAPK/HSP27 in glioma.
Glioma
Different constitutive heat shock protein 70 expression during proliferation and differentiation of rat C6 glioma cells.
Glioma
Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78.
Glioma
Differential effects of cysteamine on heat shock protein induction and cytoplasmic granulation in astrocytes and glioma cells.
Glioma
Disruption of the EF-2 kinase/Hsp90 protein complex: a possible mechanism to inhibit glioblastoma by geldanamycin.
Glioma
Effect of heat shock on intracellular calcium mobilization in neuroblastoma x glioma hybrid cells.
Glioma
Effects of alcohol on gene expression in neural cells.
Glioma
Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells.
Glioma
Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas.
Glioma
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
Glioma
Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling.
Glioma
Endoplasmic reticulum stress upregulates the chondroitin sulfate level which thus prevents neurite extension in C6 glioma cells and primary cultured astrocytes.
Glioma
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases.
Glioma
Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90.
Glioma
Ethanol-responsive genes in neural cells include the 78-kilodalton glucose-regulated protein (GRP78) and 94-kilodalton glucose-regulated protein (GRP94) molecular chaperones.
Glioma
Exogenous H2S promotes cancer progression by activating JAK2/STAT3 signaling pathway in esophageal EC109 cells.
Glioma
Expression analysis of mortalin, a unique member of the Hsp70 family of proteins, in rat tissues.
Glioma
Expression and functional activity of heat shock proteins in human glioblastoma multiforme.
Glioma
Expression of heat shock proteins in brain tumors.
Glioma
Glioma progression through the prism of heat shock protein mediated extracellular matrix remodeling and epithelial to mesenchymal transition.
Glioma
Glioma: What is the role of c-Myc, hsp90 and telomerase?
Glioma
GRP78 compartmentalized redistribution in Pb-treated glia: role of GRP78 in lead-induced oxidative stress.
Glioma
GRP78 enabled micelle-based glioma targeted drug delivery.
Glioma
GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis.
Glioma
GRP78 overexpression as an unfavorable outcome in glioma patients.
Glioma
GRP78 suppresses lipid peroxidation and promotes cellular antioxidant levels in glial cells following hydrogen peroxide exposure.
Glioma
GRP78/BiP modulation of GRP78/BiP in altering sensitivity to chemotherapy.
Glioma
Heat Shock Cognate Protein 70 Enhanced Integrin ?1 Mediated Invasion in Cancer Cells.
Glioma
Heat Shock Protein 47 Promotes Glioma Angiogenesis.
Glioma
Heat shock protein 47 regulated by miR-29a to enhance glioma tumor growth and invasion.
Glioma
Heat shock protein 70 expression induces antitumor immunity during intracellular hyperthermia using magnetite nanoparticles.
Glioma
Heat shock protein 70-binding protein 1 is highly expressed in high-grade gliomas, interacts with multiple heat shock protein 70 family members, and specifically binds brain tumor cell surfaces.
Glioma
Heat shock protein 90alpha recruits FLIPS to the death-inducing signaling complex and contributes to TRAIL resistance in human glioma.
Glioma
Heat shock protein expression in human gliomas.
Glioma
Heat shock protein induction by certain chemical stressors is correlated with their cytotoxicity, lipophilicity and protein-denaturing capacity.
Glioma
Heat Shock Protein Inhibitor 17-Allyamino-17-Demethoxygeldanamycin, a Potent Inductor of Apoptosis in Human Glioma Tumor Cell Lines, Is a Weak Substrate for ABCB1 and ABCG2 Transporters.
Glioma
Heat shock protein synthesis is affected by intracellular pH: inhibition by monensin-induced alkalosis in C6 rat glioma cells.
Glioma
Hsc70 Interacts with ?4GalT5 to Regulate the Growth of Gliomas.
Glioma
Identification of amino acid appended acridines as potential leads to anti-cancer drugs.
Glioma
Identification of Novel Interaction Partners of AIF Protein on the Outer Mitochondrial Membrane.
Glioma
Image-guided control of transgene expression based on local hyperthermia.
Glioma
Immunoexpression patterns for Hypoxia-inducible Factor-1? and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
Glioma
Immunotherapy with heat shock protein 96 to treat gliomas.
Glioma
Implication of reactive oxygen species, ERK1/2, and p38MAPK in sodium salicylate-induced heat shock protein 72 expression in C6 glioma cells.
Glioma
Induction of 78 kD glucose-regulated protein (GRP78) expression and redox-regulated transcription factor activity by lead and mercury in C6 rat glioma cells.
Glioma
Induction of heat shock protein 72 in C6 glioma cells by methyl jasmonate through ROS-dependent heat shock factor 1 activation.
Glioma
Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
Glioma
Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death.
Glioma
Inhibition of Heat Shock Protein Response Enhances PS-341-Mediated Glioma Cell Death.
Glioma
Interaction of ethanol with inducers of glucose-regulated stress proteins. Ethanol potentiates inducers of grp78 transcription.
Glioma
Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells.
Glioma
Ionizing radiation improves glioma-specific targeting of superparamagnetic iron oxide nanoparticles conjugated with cmHsp70.1 monoclonal antibodies (SPION-cmHsp70.1).
Glioma
Lead targets GRP78, a molecular chaperone, in C6 rat glioma cells.
Glioma
Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation.
Glioma
Mechanisms of neuronal adaptation to ethanol. Ethanol induces Hsc70 gene transcription in NG108-15 neuroblastoma x glioma cells.
Glioma
Modulation of the arsenite-induced expression of stress proteins by reducing agents.
Glioma
Novel Functional Association of Serine Palmitoyltransferase Subunit 1-A Peptide in Sphingolipid Metabolism with Cytochrome P4501A1 Transactivation and Proliferative Capacity of the Human Glioma LN18 Brain Tumor Cell Line.
Glioma
Novel HSP90 inhibitor NVP-HSP990 targets cell cycle regulators to ablate Olig2-positive glioma tumor initiating cells.
Glioma
Nuclear translocation of stress protein Hsc70 during S phase in rat C6 glioma cells.
Glioma
Overexpression of GRP78 protects glial cells from endoplasmic reticulum stress.
Glioma
Overexpression of Hsc70 promotes proliferation, migration, and invasion of human glioma cells.
Glioma
Overexpression of ST6GalNAcV, a ganglioside-specific alpha2,6-sialyltransferase, inhibits glioma growth in vivo.
Glioma
Participation of the chaperone Hsc70 in the trafficking and functional expression of ASIC2 in glioma cells.
Glioma
Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.
Glioma
Phosphorylation status of heat shock protein 27 regulates the interleukin-1?-induced interleukin-6 synthesis in C6 glioma cells.
Glioma
Potential biomarkers of childhood brain tumor identified by proteomics of cerebrospinal fluid from extraventricular drainage (EVD).
Glioma
Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models.
Glioma
Retraction: Novel HSP90 inhibitor NVP-HSP990 targets cell-cycle regulators to ablate Olig 2-positive glioma tumor-initiating cells.
Glioma
Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death.
Glioma
Small Heat Shock Protein ?B-Crystallin Controls Shape and Adhesion of Glioma and Myoblast Cells in the Absence of Stress.
Glioma
Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells.
Glioma
Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: relevant similarities to and important differences from celecoxib.
Glioma
Suppression of glial nitric oxide synthase induction by heat shock: effects on proteolytic degradation of IkappaB-alpha.
Glioma
Synergistic interaction between 17-AAG and phosphatidylinositol 3-kinase inhibition in human malignant glioma cells.
Glioma
Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors.
Glioma
Targeted therapies for malignant glioma: progress and potential.
Glioma
Targeting GRP78 as a Basis for Enhanced Glioma Cells Killing by anti-TfR antibody.
Glioma
Targeting HSP90 in malignant gliomas: onalespib as a potential therapeutic.
Glioma
Targeting of endoplasmic reticulum (ER) stress in gliomas.
Glioma
Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA.
Glioma
The Effects of Venlafaxine and Dexamethasone on the Expression of HSP70 in Rat C6 Glioma Cells.
Glioma
The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo.
Glioma
The heat shock protein antagonist 17-AAG potentiates the activity of enzastaurin against malignant human glioma cells.
Glioma
The modulation of protein kinase A and heat shock protein 70 is involved in the reversible increase of blood-brain tumor barrier permeability induced by papaverine.
Glioma
The novel phloroglucinol derivative BFP induces apoptosis of glioma cancer through reactive oxygen species and endoplasmic reticulum stress pathways.
Glioma
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
Glioma
Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma.
Glioma
Withania somnifera Suppresses Tumor Growth of Intracranial Allograft of Glioma Cells.
Glioma
[Biodistribution of the recombinant heat shock protein rhHsp70 in intracranial C6 glioma models in Wistar rats and subcutaneos B16/F10 melanoma in C57BL/6 mice].
Glioma
[Effect of cryotherapy and 5-fluorouracil on apoptosis of G422 glioma cells]
Gliosarcoma
Concerted actions of multiple transcription elements confer differential transactivation of HSP90 isoforms in geldanamycin-treated 9L rat gliosarcoma cells.
Gliosarcoma
Control mechanisms of differential translation of Hsp90 isoforms in 9L rat gliosarcoma cells.
Gliosarcoma
Differential expression of Hsp90 isoforms in geldanamycin-treated 9L cells.
Glomerulonephritis
Collagen-binding heat shock protein (HSP) 47 expression in anti-thymocyte serum (ATS)-induced glomerulonephritis.
Glomerulonephritis
Evaluation of antibodies against human HSP60 in patients with MPO-ANCA associated glomerulonephritis: a cohort study.
Glomerulonephritis
Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal.
Glomerulonephritis
Heat shock protein 70 and anti-heat shock protein 70 antibodies in patients with chronic glomerulonephritis.
Glomerulonephritis
Heat shock protein 90 and NFkB levels in serum and urine in patients with chronic glomerulonephritis.
Glomerulonephritis
Heavy Chain Fibrillary Glomerulonephritis: A Case Report.
Glomerulonephritis
Lupus-specific kidney deposits of HSP90 are associated with altered IgG idiotypic interactions of anti-HSP90 autoantibodies.
Glomerulonephritis
Sequence homologies between hsp60 and autoantigens.
Glomerulonephritis
Toxoplasma gondii infection inhibits the development of lupus-like syndrome in autoimmune (New Zealand Black x New Zealand White) F1 mice.
Glomerulonephritis
[Investigation of 70-kDa heat shock protein in the serum and urine of patients with chronic glomerulonephritis].
Glomerulonephritis, IGA
A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase.
Glomerulonephritis, IGA
Astragalus membranaceus up-regulate Cosmc expression and reverse IgA dys-glycosylation in IgA nephropathy.
Glomerulonephritis, IGA
Coexpression of collagens and collagen-binding heat shock protein 47 in human diabetic nephropathy and IgA nephropathy.
Glomerulonephritis, IGA
External suppression causes the low expression of the Cosmc gene in IgA nephropathy.
Glomerulonephritis, IGA
MicroRNA?196b targets COSMC in pediatric IgA nephropathy.
Glomerulonephritis, IGA
Mycophenolic acid reverses IgA1 aberrant glycosylation through up-regulating Cosmc expression in IgA nephropathy.
Glomerulonephritis, IGA
Renal tubular expression of Toll-like receptor 4 in cyclosporine nephrotoxicity.
Glomerulonephritis, IGA
Small bowel T cells, HLA class II antigen DR, and GroEL stress protein in IgA nephropathy.
Glucose Intolerance
Adiponectin reduces ER stress-induced apoptosis through PPAR? transcriptional regulation of ATF2 in mouse adipose.
Glucose Intolerance
Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis.
Glucose Intolerance
Autoimmunity to HSP60 during diet induced obesity in mice.
Glucose Intolerance
Decreased Thioredoxin-1 and Increased HSP90 Expression in Skeletal Muscle in Subjects with Type 2 Diabetes or Impaired Glucose Tolerance.
Glucose Intolerance
Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice.
Glucose Intolerance
Exercise training with dietary counselling increases mitochondrial chaperone expression in middle-aged subjects with impaired glucose tolerance.
Glucose Intolerance
GRP78 overproduction in pancreatic beta cells protects against high-fat-diet-induced diabetes in mice.
Glucose Intolerance
HSP72 is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle.
Glucose Intolerance
Impaired Oxidative Metabolism and Inflammation are Associated with Insulin Resistance in ER{alpha} Deficient Mice.
Glucose Intolerance
Reduced nuclear protein 1 expression improves insulin sensitivity and protects against diet-induced glucose intolerance through up-regulation of heat shock protein 70.
Goiter
Immunomorphological Pattern of Molecular Chaperones in Normal and Pathological Thyroid Tissues and Circulating Exosomes: Potential Use in Clinics.
Gout
HSP60 Regulates Monosodium Urate Crystal-Induced Inflammation by Activating the TLR4-NF-?B-MyD88 Signaling Pathway and Disrupting Mitochondrial Function.
Graft vs Host Disease
Analysis of in vivo immunosuppressive and in vitro interaction with constitutive heat shock protein 70 activity of LF08-0299 (Tresperimus) and analogues.
Graft vs Host Disease
Combined PI3K/Akt and Hsp90 targeting synergistically suppresses essential functions of alloreactive T cells and increases Tregs.
Graft vs Host Disease
Elevated level of HSPA1L mRNA correlates with graft-versus-host disease.
Graft vs Host Disease
Heat shock protein 70: correlation of expression with degree of graft-versus-host response and clinical graft-versus-host disease.
Graft vs Host Disease
Hsp90 inhibition ameliorates CD4(+) T cell-mediated acute Graft versus Host disease in mice.
Graft vs Host Disease
Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice.
Graft vs Host Disease
Selective depletion of alloreactive T cells by targeted therapy of heat shock protein 90: a novel strategy for control of graft-versus-host disease.
Graft vs Host Disease
The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development.
Gram-Negative Bacterial Infections
Crosstalk Between Nuclear Glucose-Regulated Protein 78 and Tumor Protein 53 Contributes to the Lipopolysaccharide Aggravated Apoptosis of Endoplasmic Reticulum Stress-Responsive Porcine Intestinal Epithelial Cells.
Granuloma
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.
Granuloma
Identification of Mycobacterium marinum 65 kD heat shock protein gene by polymerase chain reaction restriction analysis from lesions of swimming pool granuloma.
Granuloma
Involvement of heat shock protein 47 in Schistosoma japonicum-induced hepatic fibrosis in mice.
Granuloma
[Histological and immunohistochemical structure of pulmonary tuberculotic granulomas in untreated cases and cases treated with antitubercular drugs]
Graves Disease
Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid Graves' disease.
Graves Disease
Heat shock protein 70 polymorphisms in Chinese patients with Graves' disease.
Graves Disease
Induction in vitro of 72-kD heat shock protein in a continuous culture of rat thyroid cells, FRTL5.
Graves Disease
Interferon gamma and iodide increase the inducibility of the 72 kD heat shock protein in cultured human thyroid epithelial cells.
Graves Ophthalmopathy
Human histocompatibility leukocyte antigen-DR and heat shock protein-70 expression in eye muscle tissue in thyroid-associated ophthalmopathy.
Guillain-Barre Syndrome
Serum antibody level against GroEL type heat-shock protein of Campylobacter jejuni in patients with Guillain-Barré syndrome.
Haemophilus Infections
Cross-reactive antigens shared by Pseudomonas aeruginosa, Helicobacter pylori, Campylobacter jejuni, and Haemophilus influenzae may cause false-positive titers of antibody to H. pylori.
Hamman-Rich Syndrome
Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia.
Head and Neck Neoplasms
Association between hsp60 messenger-RNA levels and Cisplatin resistance in human head and neck-cancer cell-lines.
Head and Neck Neoplasms
Carboxy-terminus Hsc70 interacting protein exerts a tumor inhibition function in head and neck cancer.
Head and Neck Neoplasms
Expression of ?B-crystallin and its potential anti-apoptotic role in oral verrucous carcinoma.
Head and Neck Neoplasms
Grp78 as a therapeutic target for refractory head-neck cancer with CD24(-)CD44(+) stemness phenotype.
Head and Neck Neoplasms
HSP27 regulates viability and migration of cancer cell lines following irradiation.
Head and Neck Neoplasms
HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling.
Head and Neck Neoplasms
HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation.
Head and Neck Neoplasms
Inducible promoters for gene therapy of head and neck cancer: an in vitro study.
Head and Neck Neoplasms
Interaction between HSP60 and {beta}-catenin promotes metastasis.
Head and Neck Neoplasms
Molecular mechanisms of anti-tumor properties of P276-00 in head and neck squamous cell carcinoma.
Head and Neck Neoplasms
Overcoming Limitations of Cisplatin Therapy by Additional Treatment With the HSP90 Inhibitor Onalespib.
Head and Neck Neoplasms
The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness.
Head and Neck Neoplasms
The Hsp90 inhibitor 17-(allylamino)-17-demethoxygeldanamycin increases cisplatin antitumor activity by inducing p53-mediated apoptosis in head and neck cancer.
Head and Neck Neoplasms
Wild-type EGFR Is Stabilized by Direct Interaction with HSP90 in Cancer Cells and Tumors.
Head Injuries, Closed
Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury.
Hearing Loss
Anti-inflammatory and Oto-Protective Effect of the Small Heat Shock Protein Alpha B-Crystallin (HspB5) in Experimental Pneumococcal Meningitis.
Hearing Loss
Attenuation of progressive hearing loss in a model of age-related hearing loss by a heat shock protein inducer, geranylgeranylacetone.
Hearing Loss
Autoimmune sensorineural hearing loss: is it still a clinical diagnosis?
Hearing Loss
Failure of elevated heat shock protein 70 antibodies to alter cochlear function in mice.
Hearing Loss
Polymorphisms of heat shock protein 70 genes (HSPA1A, HSPA1B and HSPA1L) and susceptibility of noise-induced hearing loss in a Chinese population: A case-control study.
Hearing Loss
Targeted delivery of geranylgeranylacetone to mitochondria by triphenylphosphonium modified nanoparticles: a promising strategy to prevent aminoglycoside-induced hearing loss.
Hearing Loss
The association of heat shock protein genetic polymorphisms with age-related hearing impairment in Taiwan.
Hearing Loss
Upregulation of HSP60 expression in the postnatal rat cochlea and rats with drug-induced hearing loss.
Hearing Loss
[Hearing loss -- can heat shock protein 70 be cited as prognostic marker?]
Hearing Loss
[To the question of genetic predisposition to the development of professional sensorineural hearing loss].
Hearing Loss, Noise-Induced
Association between polymorphisms of heat-shock protein 70 genes and noise-induced hearing loss: A meta-analysis.
Hearing Loss, Noise-Induced
Association of polymorphisms in heat shock protein 70 genes with the susceptibility to noise-induced hearing loss: A meta-analysis.
Hearing Loss, Noise-Induced
Association of Polymorphisms of Heat Shock Protein 70 with Susceptibility to Noise-Induced Hearing Loss in the Taiwanese Population.
Hearing Loss, Noise-Induced
Correction: Association between polymorphisms of heat-shock protein 70 genes and noise-induced hearing loss: A meta-analysis.
Hearing Loss, Noise-Induced
Correction: Association of polymorphisms in heat shock protein 70 genes with the susceptibility to noise-induced hearing loss: A meta-analysis.
Hearing Loss, Noise-Induced
Polymorphisms of heat shock protein 70 genes (HSPA1A, HSPA1B and HSPA1L) and susceptibility of noise-induced hearing loss in a Chinese population: A case-control study.
Hearing Loss, Noise-Induced
[Association between single nucleotide polymorphismsin human heat shock protein 70 gene and susceptibility to noise-induced hearing loss].
Hearing Loss, Sensorineural
Antibodies to HSP-70 in normal donors and autoimmune hearing loss patients.
Hearing Loss, Sensorineural
Antibody reactivity to heat shock protein 70 and inner ear-specific proteins in patients with idiopathic sensorineural hearing loss.
Hearing Loss, Sensorineural
Circulating Immune Complexes and Heat Shock Protein 70 in the Sera of Patients with Sudden Sensorineural Hearing Loss.
Hearing Loss, Sensorineural
Evidence linking the 68 kilodalton antigen identified in progressive sensorineural hearing loss patient sera with heat shock protein 70.
Hearing Loss, Sensorineural
Heat Shock Protein 70 Gene Polymorphisms in Sudden Sensorineural Hearing Loss.
Hearing Loss, Sensorineural
Recognition of a dominant epitope in bovine heat-shock protein 70 in inner ear disease.
Hearing Loss, Sensorineural
Serum antibodies to heat shock protein 70 in sensorineural hearing loss.
Hearing Loss, Sensorineural
Serum heat shock protein 70 and its correlation with clinical characteristics in patients with sudden sensorineural hearing loss.
Hearing Loss, Sensorineural
[Detection of humoral immune response to inner ear proteins in patients with sensorineural hearing loss]
Hearing Loss, Sudden
Evaluation of anti-hsp70 antibody screening in sudden deafness.
Heart Arrest
Prediction of an Epitope-based Computational Vaccine Strategy for Gaining Concurrent Immunization Against the Venom Proteins of Australian Box Jellyfish.
Heart Defects, Congenital
Heat shock protein 70-1 gene expression in pediatric heart surgery using blood cardioplegia.
Heart Defects, Congenital
Heat shock protein 72 expression in the right ventricle of patients undergoing congenital cardiac surgery.
Heart Defects, Congenital
No variation in Hsp70 mRNA level during cardiac surgery in pediatric patients evaluated by semiquantitative RT-PCR.
Heart Defects, Congenital
Right ventricle of patients undergoing congenital cardiac surgery differentially expresses haem oxygenase-1 and heat shock protein 70 genes.
Heart Defects, Congenital
The extracellular stress response to pediatric cardiopulmonary bypass.
Heart Defects, Congenital
[Expression of the heat shock protein-70 in the myocardial cells of cyanosis congenital heart diseases]
Heart Diseases
Autoimmune diseases and Helicobacter pylori infection.
Heart Diseases
Bartonella strains from ground squirrels are identical to Bartonella washoensis isolated from a human patient.
Heart Diseases
Circulating heat shock proteins and inflammatory markers in patients with idiopathic left ventricular dysfunction: their relationships with myocardial and microvascular impairment.
Heart Diseases
Elevated antibody levels against Chlamydia pneumoniae, human HSP60 and mycobacterial HSP65 are independent risk factors in myocardial infarction and ischaemic heart disease.
Heart Diseases
Helicobacter pylori and cardiovascular complications: a mechanism based review on role of Helicobacter pylori in cardiovascular diseases.
Heart Diseases
Hold me tight: Role of the heat shock protein family of chaperones in cardiac disease.
Heart Diseases
Keep your heart in shape: molecular chaperone networks for treating heart disease.
Heart Diseases
Progression of the role of CRYAB in signaling pathways and cancers.
Heart Diseases
Proteome dynamics and proteome function of cardiac 19S proteasomes.
Heart Diseases
The stress response: implications for the clinical development of hsp90 inhibitors.
Heart Diseases
Transforming growth factor-?-activated kinase 1 enhances H2O2-induced apoptosis independently of reactive oxygen species in cardiomyocytes.
Heart Failure
Akt1 expression and activity at different stages in experimental heart failure.
Heart Failure
Aspirin Enhances the Protection of Hsp90 from Heat-Stressed Injury in Cardiac Microvascular Endothelial Cells Through PI3K-Akt and PKM2 Pathways.
Heart Failure
Changes in Expressions of HSP27, HSP70, and Soluble Glycoprotein in Heart Failure Rats Complicated with Pulmonary Edema and Correlations with Cardiopulmonary Functions.
Heart Failure
Changes in Hsp60 level of the failing heart following acute myocardial infarction and the effect of long-term treatment with trandolapril.
Heart Failure
Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure.
Heart Failure
Effects of Hsp90 inhibitor on the RIP1-RIP3-MLKL pathway during the development of heart failure in mice.
Heart Failure
Elevated circulating levels of heat shock protein 70 are related to systemic inflammatory reaction through monocyte Toll signal in patients with heart failure after acute myocardial infarction.
Heart Failure
Extracellular Heat Shock Protein 60, Cardiac Myocytes, and Apoptosis.
Heart Failure
Functional proteomic analysis of experimental autoimmune myocarditis-induced chronic heart failure in the rat.
Heart Failure
H11 Kinase/Heat Shock Protein 22 Deletion Impairs Both Nuclear and Mitochondrial Functions of STAT3 and Accelerates the Transition Into Heart Failure on Cardiac Overload.
Heart Failure
Heat shock protein 27 acts as a predictor of prognosis in chronic heart failure patients.
Heart Failure
Heat shock protein 27 acts as a predictor of prognosis in chronic heart failure patients: Methodological issues.
Heart Failure
Heat Shock Protein 60 in Cardiovascular Physiology and Diseases.
Heart Failure
Heat shock protein 70 acts as a potential biomarker for early diagnosis of heart failure.
Heart Failure
Heat shock protein 70 in patients with chronic heart failure: relation to disease severity and survival.
Heart Failure
HSP60 in heart failure: abnormal distribution and role in cardiac myocyte apoptosis.
Heart Failure
Hsp90 and its co-chaperone, Sgt1, as autoantigens in dilated cardiomyopathy.
Heart Failure
Hsp90 Inhibitor Attenuates the Development of Pathophysiological Cardiac Fibrosis in Mouse Hypertrophy via Suppression of the Calcineurin-NFAT and c-Raf-Erk Pathways.
Heart Failure
Induction of heat shock protein 72 in the failing heart is attenuated after an exposure to heat shock.
Heart Failure
Interaction of serum 70-kDa heat shock protein levels and HspA1B (+1267) gene polymorphism with disease severity in patients with chronic heart failure.
Heart Failure
Metolazone upregulates mitochondrial chaperones and extends lifespan in Caenorhabditis elegans.
Heart Failure
Molecular chaperone, HSP60, and cytochrome P450 2E1 co-expression in dilated cardiomyopathy.
Heart Failure
Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression.
Heart Failure
PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.
Heart Failure
Proteomic Analysis Reveals Significant Alternations of Cardiac Small Heat Shock Protein Expression in Congestive Heart Failure.
Heart Failure
Proteomic analysis reveals significant elevation of heat shock protein 70 in patients with chronic heart failure due to arrhythmogenic right ventricular cardiomyopathy.
Heart Failure
Refined purification of large amounts of Rat cvHsp/HspB7 and partial biological characterization in vitro.
Heart Failure
Regulation of heat shock protein 60 and 72 expression in the failing heart.
Heart Failure
Regulation of kinase cascade activation and heat shock protein expression by poly(ADP-ribose) polymerase inhibition in doxorubicin-induced heart failure.
Heart Failure
Right heart failure chronically stimulates heat shock protein 72 in heart and liver but not in other tissues.
Heart Failure
Serum Heat Shock Protein 60 in Acute Heart Failure: A New Biomarker?
Heart Failure
Soluble Glycoprotein 130 and Heat Shock Protein 27 as Novel Candidate Biomarkers of Chronic Heart Failure with Preserved Ejection Fraction.
Heart Failure
Targeting Extracellular Heat Shock Protein 70 Ameliorates Doxorubicin-Induced Heart Failure Through Resolution of Toll-Like Receptor 2-Mediated Myocardial Inflammation.
Heart Failure
Tissue-specific small heat shock protein 20 activation is not associated with traditional autophagy markers in Ossabaw swine with cardio-metabolic heart failure.
Heart Failure
Upregulation of autophagy genes and the unfolded protein response in human heart failure.
Heart Failure
[Antibodies to Hsp60 in newborn babies, to whom during the intervention for critical inborn heart failure, autologous cord blood was transfused, in early and late postoperative period].
Heart Failure
[Useful tests to assess the clinical usefulness of new prognostic markers: the example of heart failure].
Heart Failure, Diastolic
Upregulation of GRP78 and caspase-12 in diastolic failing heart.
Heart Failure, Systolic
Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.
Heart Septal Defects, Atrial
Expression of proto-oncogenes, genes for muscle specific isoforms and heat shock protein (HSP) -70 gene in hypertrophied cardiac muscles from patients with atrial septal defect or tetralogy of Fallot.
Heart Septal Defects, Ventricular
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
Heart Valve Diseases
Anti-Heat Shock Protein 27 Titers and Oxidative Stress Levels are Elevated in Patients With Valvular Heart Disease.
HELLP Syndrome
Elevated serum 70 kDa heat shock protein level reflects tissue damage and disease severity in the syndrome of hemolysis, elevated liver enzymes, and low platelet count.
HELLP Syndrome
Placenta derived factors involved in the pathogenesis of the liver in the syndrome of haemolysis, elevated liver enzymes and low platelets (HELLP): A review.
Hemangioma
Inhibition of heat shock protein 90 exerts an antitumour effect in angiosarcoma: involvement of the vascular endothelial growth factor signalling pathway.
Hemangiosarcoma
HSP90 inhibition in angiosarcoma.
Hemangiosarcoma
Inhibition of heat shock protein 90 exerts an antitumour effect in angiosarcoma: involvement of the vascular endothelial growth factor signalling pathway.
Hematologic Diseases
Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly.
Hematologic Neoplasms
17-DMAG disrupted the autophagy flux leading to the apoptosis of acute lymphoblastic leukemia cells by inducing heat shock cognate protein 70.
Hematologic Neoplasms
Antimyeloma activity of heat shock protein-90 inhibition.
Hematologic Neoplasms
BIIB021, an Hsp90 inhibitor: A promising therapeutic strategy for blood malignancies (Review).
Hematologic Neoplasms
CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells.
Hematologic Neoplasms
Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux.
Hematologic Neoplasms
Heat shock protein 90 and role of its chemical inhibitors in treatment of hematologic malignancies.
Hematologic Neoplasms
Heat Shock Proteins: A Potential Anticancer Target.
Hematologic Neoplasms
Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.
Hematologic Neoplasms
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Hematologic Neoplasms
Phase I trial of the HSP90 inhibitor PF-04929113 (SNX5422) in adult patients with recurrent, refractory hematologic malignancies.
Hematologic Neoplasms
Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL.
Hematologic Neoplasms
The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1.
Hematologic Neoplasms
The Hsp32 inhibitors SMA-ZnPP and PEG-ZnPP exert major growth-inhibitory effects on D34(+)/CD38(+) and CD34(+)/CD38(-) AML progenitor cells.
Hematologic Neoplasms
The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine.
Hemochromatosis
Inflammation, genetics, and ischemic heart disease: focus on the major histocompatibility complex (MHC) genes.
Hemochromatosis
Platelet-derived ?2M regulates monocyte inflammatory responses.
Hemorrhagic Fever, Crimean
Heat Shock Protein 70 family members interact with Crimean-Congo hemorrhagic fever virus and Hazara virus nucleocapsid proteins and perform a functional role in the nairovirus replication cycle.
Hemorrhagic Fever, Ebola
Ebola virus infection induces autoimmunity against dsDNA and HSP60.
Hemorrhagic Septicemia, Viral
VER-155008 induced Hsp70 proteins expression in fish cell cultures while impeding replication of two RNA viruses.
Hemorrhagic Stroke
[Protective and antiedema effect of heat shock protein hsp70 studied in vitro on hemorrhagic stroke model in nervous tissue].
Hepatitis
Autoimmunity in chronic active Helicobacter hepatitis of mice. Serum antibodies and expression of heat shock protein 70 in liver.
Hepatitis
Evaluating post-transcriptional regulatory elements for enhancing transient gene expression levels in CHO K1 and HEK293 cells.
Hepatitis
Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2.
Hepatitis
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines.
Hepatitis
Mitochondrial HSP70, HSP40, and HSP60 bind to the 3' untranslated region of the Murine hepatitis virus genome.
Hepatitis
Sequence homologies between hsp60 and autoantigens.
Hepatitis
Telomerase repeat amplification protocol (TRAP) activity upon recombinant expression and purification of human telomerase in a bacterial system.
Hepatitis A
Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production.
Hepatitis A
Use of urinary biomarkers of renal ischemia in a lamb preclinical left ventricular assist device model.
Hepatitis A
Viral contamination of shellfish: evaluation of methods and analysis of bacteriophages and human viruses.
Hepatitis B
A novel virus-like particle based on hepatitis B core antigen and substrate-binding domain of bacterial molecular chaperone DnaK.
Hepatitis B
A tetratricopeptide repeat half-site in the aryl hydrocarbon receptor is important for DNA binding and trans-activation potential.
Hepatitis B
Antisense oligodeoxynucleotides targeted against molecular chaperonin Hsp60 block human hepatitis B virus replication.
Hepatitis B
Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2.
Hepatitis B
Binding site analysis of human HBV pol for molecular chaperonin, hsp60.
Hepatitis B
CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation.
Hepatitis B
Chaperone action in the posttranslational topological reorientation of the hepatitis B virus large envelope protein: Implications for translocational regulation.
Hepatitis B
Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization.
Hepatitis B
Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2.
Hepatitis B
Complex Formation between Heat Shock Protein 72 and Hepatitis B Virus X Protein in Hepatocellular Carcinoma Tissues.
Hepatitis B
Complex formation between heat shock protein 72 and hepatitis B virus X protein in hepatocellular carcinoma tissues.
Hepatitis B
Concomitant cellular expression of heat shock regulated genes of hepatitis B virus surface antigen and of human growth hormone by a NIH-3T3 cell line.
Hepatitis B
Defining the role for XAP2 in stabilization of the dioxin receptor.
Hepatitis B
Design and Synthesis of Oxymatrine Analogues Overcoming Drug Resistance in Hepatitis B Virus through Targeting Host Heat Stress Cognate 70.
Hepatitis B
Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes.
Hepatitis B
Efficient Hsp90-independent in vitro activation by Hsc70 and Hsp40 of duck hepatitis B virus reverse transcriptase, an assumed Hsp90 client protein.
Hepatitis B
Endogenous hepatic expression of the hepatitis B virus X-associated protein 2 is adequate for maximal association with aryl hydrocarbon receptor-90-kDa heat shock protein complexes.
Hepatitis B
Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2.
Hepatitis B
Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules.
Hepatitis B
Functional role of Hsp60 as a positive regulator of human viral infection progression.
Hepatitis B
Functional roles of GRP78 in hepatitis B virus infectivity and antigen secretion.
Hepatitis B
Generation of murine CTL by a hepatitis B virus-specific peptide and evaluation of the adjuvant effect of heat shock protein glycoprotein 96 and its terminal fragments.
Hepatitis B
Glucose-Regulated Protein 78 Is an Intracellular Antiviral Factor against Hepatitis B Virus.
Hepatitis B
HBx protein of hepatitis B virus (HBV) can form complex with mitochondrial HSP60 and HSP70.
Hepatitis B
Heat shock protein 70 and heat shock protein 90 synergistically increase hepatitis B viral capsid assembly.
Hepatitis B
Heat shock protein 90-independent activation of truncated hepadnavirus reverse transcriptase.
Hepatitis B
Heat shock proteins stimulate APOBEC-3-mediated cytidine deamination in the hepatitis B virus.
Hepatitis B
Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids.
Hepatitis B
Hepatitis B virus replication could enhance regulatory T cell activity by producing soluble heat shock protein 60 from hepatocytes.
Hepatitis B
Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2.
Hepatitis B
Hsp90 is required for the activity of a hepatitis B virus reverse transcriptase.
Hepatitis B
Hsp90 makes the human HBV Pol competent for in vitro priming rather than maintaining the human HBV Pol/pregenomic RNA complex.
Hepatitis B
Human hepatitis B virus polymerase interacts with the molecular chaperonin Hsp60.
Hepatitis B
In vitro reconstitution of a functional duck hepatitis B virus reverse transcriptase: posttranslational activation by Hsp90.
Hepatitis B
In vitro reconstitution of functional hepadnavirus reverse transcriptase with cellular chaperone proteins.
Hepatitis B
Increased expression of Gp96 by HBx-induced NF-?B activation feedback enhances hepatitis B virus production.
Hepatitis B
Induction of apurinic endonuclease 1 overexpression by endoplasmic reticulum stress in hepatoma cells.
Hepatitis B
Inhibition of Heme Oxygenase-1 Partially Reverses the Arsenite-Mediated Decrease of CYP1A1, CYP1A2, CYP3A23, and CYP3A2 Catalytic Activity in Isolated Rat Hepatocytes.
Hepatitis B
Localization of HSP90 binding sites in the human hepatitis B virus polymerase.
Hepatitis B
Molecular chaperone GRP78/BiP interacts with the large surface protein of hepatitis B virus in vitro and in vivo.
Hepatitis B
Phosphorylation analysis of 90 kDa heat shock protein within the cytosolic arylhydrocarbon receptor complex.
Hepatitis B
Recombinant heat shock protein 65 carrying hepatitis B core antigen induces HBcAg-specific CTL response.
Hepatitis B
Regulation of Molecular Chaperone GRP78 by Hepatitis B Virus: Control of Viral Replication and Cell Survival.
Hepatitis B
Requirement of heat shock protein 90 for human hepatitis B virus reverse transcriptase function.
Hepatitis B
Role of p50/CDC37 in hepadnavirus assembly and replication.
Hepatitis B
Sequence-specific repression of cotranslational translocation of the hepatitis B virus envelope proteins coincides with binding of heat shock protein Hsc70.
Hepatitis B
Targeting hepatitis B virus antigens to dendritic cells by heat shock protein to improve DNA vaccine potency.
Hepatitis B
The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo.
Hepatitis B
The hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activity.
Hepatitis B
The role of heat shock protein 27 expression in hepatocellular carcinoma in Japan: special reference to the difference between hepatitis B and C.
Hepatitis B
Two-dimensional blue native/SDS-PAGE analysis reveals heat shock protein chaperone machinery involved in hepatitis B virus production in HepG2.2.15 cells.
Hepatitis B
[Heat shock protein 90-mediated inhibition of hepatitis B virus replication in hepatic cells].
Hepatitis B
[Immune adjuvant effect of TB.HSP70 to its accompanying cytotoxic T lymphocytes epitope elicits HBV specific immune response]
Hepatitis B
[Regulation of hepatitis B virus X protein on the expression of HSP90a gene in human hepatocarcinoma cells.]
Hepatitis B, Chronic
Expression of heat shock protein 47, transforming growth factor-beta 1, and connective tissue growth factor in liver tissue of patients with Schistosoma japonicum-induced hepatic fibrosis.
Hepatitis B, Chronic
Genetic variants of heat shock protein A1L2437 and A1B1267 as possible risk factors for hepatocellular carcinoma in India.
Hepatitis B, Chronic
Glucose-Regulated Protein 78 Is an Intracellular Antiviral Factor against Hepatitis B Virus.
Hepatitis B, Chronic
Hepatitis B virus replication could enhance regulatory T cell activity by producing soluble heat shock protein 60 from hepatocytes.
Hepatitis B, Chronic
[Expression and significance of HSP27, HSP70 and HSP90 alpha in the livers of chronic hepatitis B patients]
Hepatitis B, Chronic
[Study of endoplasmic reticulum stress role in hepatic failure induced by severe hepatitis B].
Hepatitis C
A telomerase-derived peptide regulates reactive oxygen species and hepatitis C virus RNA replication in HCV-infected cells via heat shock protein 90.
Hepatitis C
Activation of the grp78 and grp94 promoters by hepatitis C virus E2 envelope protein.
Hepatitis C
Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly.
Hepatitis C
Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production.
Hepatitis C
Ca(2+) /S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication.
Hepatitis C
Cellular Growth Kinetics Distinguish a Cyclophilin Inhibitor from an HSP90 Inhibitor as a Selective Inhibitor of Hepatitis C Virus.
Hepatitis C
Combination therapy for hepatitis C virus with heat-shock protein 90 inhibitor 17-AAG and proteasome inhibitor MG132.
Hepatitis C
Concomitant overexpression of heat-shock protein 70 and HLA class-I in hepatitis C virus-related hepatocellular carcinoma.
Hepatitis C
Dendritic cells transfected with heat-shock protein 70 messenger RNA for patients with hepatitis C virus-related hepatocellular carcinoma: a phase 1 dose escalation clinical trial.
Hepatitis C
Destabilization of PDK1 by Hsp90 inactivation suppresses hepatitis C virus replication through inhibition of PRK2-mediated viral RNA polymerase phosphorylation.
Hepatitis C
Detection of antibodies to 65 KD heat shock protein and to human superoxide dismutase in autoimmune hepatitis-molecular mimicry between 65 KD heat shock protein and superoxide dismutase.
Hepatitis C
Heat shock protein 72 is associated with the hepatitis C virus replicase complex and enhances viral RNA replication.
Hepatitis C
Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3.
Hepatitis C
Hepatitis C virus inhibitor synergism suggests multistep interactions between heat-shock protein 90 and hepatitis C virus replication.
Hepatitis C
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90.
Hepatitis C
Host cell factor requirement for hepatitis C virus enzyme maturation.
Hepatitis C
Inhibition of Hepatitis C Replication by Targeting the Molecular Chaperone Hsp90: Synthesis and Biological Evaluation of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazole Derivatives.
Hepatitis C
Inhibition of hepatitis C virus using siRNA targeted to the virus and Hsp90.
Hepatitis C
Interaction of hepatitis C virus core protein with Hsp60 triggers the production of reactive oxygen species and enhances TNF-alpha-mediated apoptosis.
Hepatitis C
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors.
Hepatitis C
Nonstructural 5A protein of hepatitis C virus regulates heat shock protein 72 for its own propagation.
Hepatitis C
Proteomic profiling of heat shock protein 70 family members as biomarkers for hepatitis C virus-related hepatocellular carcinoma.
Hepatitis C
Small molecular compounds that inhibit hepatitis C virus replication through destabilizing heat shock cognate 70 messenger RNA.
Hepatitis C
The heat shock cognate protein 70 is associated with hepatitis C virus particles and modulates virus infectivity.
Hepatitis C
The heat shock protein inhibitor Quercetin Attenuates hepatitis C virus production.
Hepatitis C
The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.
Hepatitis C
The Molecular Chaperone GRP78 Contributes to Toll-like Receptor 3-mediated Innate Immune Response to Hepatitis C Virus in Hepatocytes.
Hepatitis C
The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle.
Hepatitis C
Tylophorine Analogs Allosterically Regulates Heat Shock Cognate Protein 70 And Inhibits Hepatitis C Virus Replication.
Hepatitis C
[Detection of serum heat shock protein 70 level in patients with hepatitis C infection and its role in cytotoxicity of CTLs induced by HSP70-HCV peptide complex]
Hepatitis C, Chronic
La protein required for internal ribosome entry site-directed translation is a potential therapeutic target for hepatitis C virus replication.
Hepatitis C, Chronic
The Molecular Chaperone GRP78 Contributes to Toll-like Receptor 3-mediated Innate Immune Response to Hepatitis C Virus in Hepatocytes.
Hepatitis E
Homology model and potential virus-capsid binding site of a putative HEV receptor Grp78.
Hepatitis E
Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90.
Hepatitis E
The role of Heat Shock Protein 90 (HSP90) in Hepatitis E Virus (HEV) Capsid Trafficking.
Hepatitis, Alcoholic
Circulating IgA antibody against a 65 kDa heat shock protein in acute alcoholic hepatitis.
Hepatitis, Autoimmune
Detection of antibodies to 65 KD heat shock protein and to human superoxide dismutase in autoimmune hepatitis-molecular mimicry between 65 KD heat shock protein and superoxide dismutase.
Hepatitis, Autoimmune
Immuno-gold electron microscopical detection of heat shock protein 60 (hsp60) in mitochondria of rat hepatocytes and myocardiocytes.
Hepatitis, Chronic
Detection of antibodies to 65 KD heat shock protein and to human superoxide dismutase in autoimmune hepatitis-molecular mimicry between 65 KD heat shock protein and superoxide dismutase.
Hepatitis, Chronic
Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.
Hepatitis, Chronic
Sequence homologies between hsp60 and autoantigens.
Hepatoblastoma
Heat shock gene expression and development of translational thermotolerance in human hepatoblastoma cells.
Hepatoblastoma
[Expression of GRP78 and GRP94 in the liver tissues and their clinicopathological significance in children with hepatoblastoma].
Hepatomegaly
GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Hepatopulmonary Syndrome
Opposite regulation of endothelial NO synthase by HSP90 and caveolin in liver and lungs of rats with hepatopulmonary syndrome.
Hepatorenal Syndrome
[Study on the expressions and roles of renal heat shock protein 72 and Toll-like receptor 4 in hepatorenal syndrome in rat]
Herpes Simplex
A cellular protein related to heat-shock protein 90 accumulates during herpes simplex virus infection and is overexpressed in transformed cells.
Herpes Simplex
An intranasal heat shock protein based vaccination strategy confers protection against mucosal challenge with herpes simplex virus.
Herpes Simplex
Antigenic peptides complexed to phylogenically diverse Hsp70s induce differential immune responses.
Herpes Simplex
Characterization of HPV-16 E6 DNA vaccines employing intracellular targeting and intercellular spreading strategies.
Herpes Simplex
Defective herpes simplex virus vectors expressing the rat brain stress-inducible heat shock protein 72 protect cultured neurons from severe heat shock.
Herpes Simplex
Dual role of infections as risk factors for coronary heart disease.
Herpes Simplex
Elevated antibody levels against Chlamydia pneumoniae, human HSP60 and mycobacterial HSP65 are independent risk factors in myocardial infarction and ischaemic heart disease.
Herpes Simplex
Geldanamycin, a ligand of heat shock protein 90, inhibits herpes simplex virus type 2 replication both in vitro and in vivo.
Herpes Simplex
Geldanamycin, a ligand of heat shock protein 90, inhibits the replication of herpes simplex virus type 1 in vitro.
Herpes Simplex
Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss.
Herpes Simplex
Heat-shock protein 70 acts as an effective adjuvant in neonatal mice and confers protection against challenge with herpes simplex virus.
Herpes Simplex
Heat-shock protein 90 promotes nuclear transport of herpes simplex virus 1 capsid protein by interacting with acetylated tubulin.
Herpes Simplex
Heat-shock protein 90? is involved in maintaining the stability of VP16 and VP16-mediated transactivation of ? genes from herpes simplex virus-1.
Herpes Simplex
Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus.
Herpes Simplex
Herpes simplex virus type 2 encodes a heat shock protein homologue with apoptosis regulatory functions.
Herpes Simplex
Herpes simplex virus type 2 UL14 gene product has heat shock protein (HSP)-like functions.
Herpes Simplex
Herpes simplex virus-induced expression of 70 kDa heat shock protein (HSP70) requires early protein synthesis but not viral DNA replication.
Herpes Simplex
Hsc70 Focus Formation at the Periphery of HSV-1 Transcription Sites Requires ICP27.
Herpes Simplex
Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice.
Herpes Simplex
Phase I dose-escalation study of a monovalent heat shock protein 70-herpes simplex virus type 2 (HSV-2) peptide-based vaccine designed to prime or boost CD8 T-cell responses in HSV-naïve and HSV-2-infected subjects.
Herpes Simplex
Publisher Correction: ?? TCR ligands: the quest to solve a 500-million-year-old mystery.
Herpes Simplex
Suppression of herpes simplex virus 1 reactivation in a mouse eye model by cyclooxygenase inhibitor, heat shock protein inhibitor, and adenosine monophosphate.
Herpes Simplex
Suppression of murine melanoma growth by a vaccine of attenuated Salmonella carrying heat shock protein 70 and Herpes simplex virus-thymidine kinase genes.
Herpes Simplex
The Herpes Simplex Virus 1 Immediate Early Protein ICP22 Is a Functional Mimic of a Cellular J Protein.
Herpes Simplex
The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1.
Herpes Simplex
Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I.
Herpes Simplex
Use of the glucose starvation-inducible glucose-regulated protein 78 promoter in suicide gene therapy of murine fibrosarcoma.
Herpes Simplex
[Intratumor injection of recombinant attenuated salmonella carrying Mycobacterium tuberculosis heat shock protein 70 and herpes simplex virus thymidine kinase genes to suppress murine melanoma growth].
Herpes Zoster
Are Atlantic cod in Store Lungegårdsvann, a seawater recipient in Bergen, affected by environmental contaminants? A qRT-PCR survey.
Herpes Zoster
Novel characterization of the HSPA2-stabilizing protein BAG6 in human spermatozoa.
Herpes Zoster
Nuclear transfer technique affects mRNA abundance, developmental competence, and cell fate of the reconstituted sheep oocytes.
Herpes Zoster
Proteomic Analysis of Human Blastocoel Fluid and Blastocyst Cells.
Herpes Zoster
Sense and antisense transcripts of the developmentally regulated murine hsp70.2 gene are expressed in distinct and only partially overlapping areas in the adult brain.
Herpes Zoster
The impact of oxidative stress on chaperone-mediated human sperm-egg interaction.
Herpes Zoster
Vitellogenin, zona radiata protein, cathepsin D and heat shock protein 70 as biomarkers of exposure to xenobiotics.
Herpesviridae Infections
miR-16-1 expression, heat shock protein 70 and inflammatory reactions in astrocytes of mice with epilepsy induced by encephalitis B virus infection.
Herpesviridae Infections
Morphofunctional characteristics of syncytiotrophoblast and content of heat shock protein 70 in it during exacerbation of herpesvirus infection in pregnant women.
Histiocytoma
Hsp90 inhibitors, GA and 17AAG, lead to ER stress-induced apoptosis in rat histiocytoma.
Histiocytoma, Malignant Fibrous
Hsp-27 has no diagnostic or prognostic significance in prostate or bladder cancers.
Histiocytoma, Malignant Fibrous
Hsp27 expression in neuroblastoma: correlation with disease stage.
Histoplasmosis
Agglutination of Histoplasma capsulatum by IgG monoclonal antibodies against Hsp60 impacts macrophage effector functions.
Histoplasmosis
Heterologous expression, purification, and immunological reactivity of a recombinant HSP60 from Paracoccidioides brasiliensis.
Histoplasmosis
Histoplasma capsulatum heat-shock 60 orchestrates the adaptation of the fungus to temperature stress.
Histoplasmosis
Isolation and characterization of an immunogenic fragment of heat shock protein 60 from Trichophyton mentagrophytes.
Histoplasmosis
Monoclonal antibodies to heat shock protein 60 alter the pathogenesis of Histoplasma capsulatum.
HIV Infections
Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection.
Hodgkin Disease
Abundance of heat shock proteins (hsp89, hsp60, and hsp27) in malignant cells of Hodgkin's disease.
Hodgkin Disease
CD30 Induces Heat Shock Protein 90 and Signal Integration in Classic Hodgkin Lymphoma Cells.
Hodgkin Disease
Expression of heat shock protein 70 (HSP70) and EBV latent membrane protein 1 (LMP1) in Reed-Sternberg cells of Hodgkin's disease.
Hodgkin Disease
Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity.
Hodgkin Disease
HSP90 is essential for Jak-STAT signaling in classical Hodgkin lymphoma cells.
Hodgkin Disease
Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
Hodgkin Disease
Targeting Hodgkin and Reed-Sternberg Cells with an Inhibitor of Heat-Shock Protein 90: Molecular Pathways of Response and Potential Mechanisms of Resistance.
Homocystinuria
Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects.
HTLV-I Infections
Heat shock cognate protein 70 is a cell fusion-enhancing factor but not an entry factor for human T-cell lymphotropic virus type I.
Huntington Disease
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
Huntington Disease
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of A?42 Amyloid Fibril Formation.
Huntington Disease
Correlation between chemotype-dependent binding conformations of HSP90?/? and isoform selectivity-Implications for the structure-based design of HSP90?/? selective inhibitors for treating neurodegenerative diseases.
Huntington Disease
Deciphering the Roles of Trehalose and Hsp104 in the Inhibition of Aggregation of Mutant Huntingtin in a Yeast Model of Huntington's Disease.
Huntington Disease
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease.
Huntington Disease
GRP78 counteracts cell death and protein aggregation caused by mutant huntingtin proteins.
Huntington Disease
Hsp104 targets multiple intermediates on the amyloid pathway and suppresses the seeding capacity of Abeta fibrils and protofibrils.
Huntington Disease
Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases.
Huntington Disease
Increased heat shock transcription factor 1 in the cerebellum reverses the deficiency of Purkinje cells in Alzheimer's disease.
Huntington Disease
Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (A?42) aggregates leads to sub-stoichiometric inhibition of amyloid formation.
Huntington Disease
Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain.
Huntington Disease
Molecular genetics approaches in yeast to study amyloid diseases.
Huntington Disease
Molecular Interaction between the Chaperone Hsc70 and the N-terminal Flank of Huntingtin Exon 1 Modulates Aggregation.
Huntington Disease
Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease.
Huntington Disease
Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression.
Huntington Disease
Overexpression of yeast hsp104 reduces polyglutamine aggregation and prolongs survival of a transgenic mouse model of Huntington's disease.
Huntington Disease
Prefoldin prevents aggregation of ?-synuclein.
Huntington Disease
Purification of hsp104, a protein disaggregase.
Huntington Disease
Structure and function of the molecular chaperone Hsp104 from yeast.
Huntington Disease
Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases.
Huntington Disease
The interaction between RE1-silencing transcription factor (REST) and heat shock protein 90 as new therapeutic target against Huntington's disease.
Huntington Disease
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Huntington Disease
Widespread remodeling of proteome solubility in response to different protein homeostasis stresses.
Hydatidiform Mole
Overexpression of GRP78 in complete hydatidiform moles.
Hydronephrosis
EVEN-PLUS syndrome: A case report with novel variants in HSPA9 and evidence of HSPA9 gene dysfunction.
Hyperalgesia
Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG.
Hyperalgesia
Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats.
Hyperalgesia
Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
Hyperalgesia
Moxibustion relieves visceral hyperalgesia via inhibition of transient receptor potential vanilloid 1 (TRPV1) and heat shock protein (HSP) 70 expression in rat bone marrow cells.
Hyperalgesia
Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats.
Hyperandrogenism
Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells.
Hypercholesterolemia
Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease: evidence for an autoimmune component of atherogenesis.
Hypercholesterolemia
Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats.
Hypercholesterolemia
Soy isoflavones reduce heat shock proteins in experimental atherosclerosis.
Hyperglycemia
Analysis of serum Hsp90 as a potential biomarker of ? cell autoimmunity in type 1 diabetes.
Hyperglycemia
Autoimmune diabetes induced by the beta-cell toxin STZ. Immunity to the 60-kDa heat shock protein and to insulin.
Hyperglycemia
Cellular responses of novel human pancreatic ?-cell line, 1.1B4 to hyperglycemia.
Hyperglycemia
Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning.
Hyperglycemia
Effect and mechanisms of zinc supplementation in protecting against diabetic cardiomyopathy in a rat model of type 2 diabetes.
Hyperglycemia
Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: establishment of a combined model and association with heat shock protein 65 immunity.
Hyperglycemia
Effect of hyperglycemia and nitric oxide synthase inhibition on heat tolerance and induction of heat shock protein 72 kDa in vivo.
Hyperglycemia
GRP78, but Not Protein-disulfide Isomerase, Partially Reverses Hyperglycemia-induced Inhibition of Insulin Synthesis and Secretion in Pancreatic {beta}-Cells.
Hyperglycemia
Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice.
Hyperglycemia
Hsp70 plays an important role in high-fat diet induced gestational hyperglycemia in mice.
Hyperglycemia
Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms.
Hyperglycemia
Hyperglycemia and antibody titres against heat shock protein 27 in traumatic brain injury patients on parenteral nutrition.
Hyperglycemia
Induction of heat shock proteins by hyperglycemic cerebral ischemia.
Hyperglycemia
Insulin deficiency downregulated heat shock protein 60 and IGF-1 receptor signaling in diabetic myocardium.
Hyperglycemia
Involvement of endoplasmic reticulum (ER) stress in podocyte injury induced by excessive protein accumulation.
Hyperglycemia
Mechanism and Consequences of The Impaired Hif-1? Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose.
Hyperglycemia
Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling.
Hyperglycemia
Severity of diabetes governs vascular lipoprotein lipase by affecting enzyme dimerization and disassembly.
Hyperglycemia
Targeting HSP90 Ameliorates Nephropathy and Atherosclerosis Through Suppression of NF-?B and STAT Signaling Pathways in Diabetic Mice.
Hyperhomocysteinemia
Synergistic Steatohepatitis by Moderate Obesity and Alcohol in Mice Despite Increased Adiponectin and p-AMPK.
Hyperlipidemias
Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: establishment of a combined model and association with heat shock protein 65 immunity.
Hyperlipidemias
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Hyperlipidemias
Hyperlipidemia induced by a cholesterol-rich diet aggravates necrotizing pancreatitis in rats.
Hyperlipidemias
Stress proteins in glomerular epithelial cell injury.
Hyperlipidemias
Targeting HSP90 Ameliorates Nephropathy and Atherosclerosis Through Suppression of NF-?B and STAT Signaling Pathways in Diabetic Mice.
Hyperoxaluria, Primary
Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I.
Hyperpigmentation
Induction of hyperpigmentation and heat shock protein 70 response to the toxicity of methomyl insecticide during the organ development of the Arabian toad, Bufo arabicus (Heyden,1827).
Hyperpigmentation
Stress chaperone mortalin regulates human melanogenesis.
Hypersensitivity
60-kDa heat shock protein of Chlamydia pneumoniae is a target of T-cell immune response.
Hypersensitivity
A trans-activation domain in yeast heat shock transcription factor is essential for cell cycle progression during stress.
Hypersensitivity
Antibody reactivity to the transmembrane protein of the caprine arthritis encephalitis virus correlates with severity of arthritis: no evidence for the involvement of epitope mimicry.
Hypersensitivity
Differential hypersensitivity to DNase I in the regulatory region of human hsp90 beta gene in heat shock and constitutive expression.
Hypersensitivity
Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice.
Hypersensitivity
HDAC6 Regulates Androgen Receptor Hypersensitivity and Nuclear Localization via Modulating Hsp90 Acetylation in Castration-Resistant Prostate Cancer.
Hypersensitivity
Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation.
Hypersensitivity
Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans.
Hypersensitivity
High positive frequency of antibodies to metallothionein and heat shock protein 70 in sera of patients with metal allergy.
Hypersensitivity
Human and guinea pig immune responses to Legionella pneumophila protein antigens OmpS and Hsp60.
Hypersensitivity
Hypersensitivity to DNA cross-linking agents associated with up-regulation of glucose-regulated stress protein GRP78.
Hypersensitivity
Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition.
Hypersensitivity
Increased sensitivity of human colon cancer cells to DNA cross-linking agents after GRP78 up-regulation.
Hypersensitivity
Isolation and sequence analysis of the Chlamydia pneumoniae GroE operon.
Hypersensitivity
Leishmania donovani P23 protects parasites against HSP90 inhibitor-mediated growth arrest.
Hypersensitivity
Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress.
Hypersensitivity
Molecular and immunological characterization of the C-terminal region of a new Echinococcus granulosus Heat Shock Protein 70.
Hypersensitivity
Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.
Hypersensitivity
Perturbation of chromatin architecture on ecdysterone induction of Drosophila melanogaster small heat shock protein genes.
Hypersensitivity
Preinduced intestinal HSP70 improves visceral hypersensitivity and abnormal intestinal motility in PI-IBS mouse model.
Hypersensitivity
Prevalence of heat shock protein in patients with Meniere's disease and allergy.
Hypersensitivity
Role of alpha beta T cells and gamma delta T cells in protective immunity to Actinobacillus actinomycetemcomitans in mutant mice by targeted gene disruption.
Hypersensitivity
Role of macrophage-mediated Toll-like receptor 4-interleukin-1R signaling in ectopic tongue pain associated with tooth pulp inflammation.
Hypersensitivity
Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster.
Hypersensitivity
TNF, LTA, HSPA1L and HLA-DR gene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole.
Hypersensitivity
Transcriptional Activation of Heat-Shock Protein 90 (Hsp90) Mediated Via a Proximal Promoter Region Confers Caspofungin Resistance in Aspergillus fumigatus.
Hypersensitivity
Virtual prototyping study shows increased ATPase activity of Hsp90 to be the key determinant of cancer phenotype.
Hypersensitivity
[Effect of Electroacupuncture and Moxibustion on Visceral Pain and Expression of VR 1 and HSP 70 of "Tianshu" (ST 25) Region in Colorectal Distension-induced Visceral Hypersensitivity Rats].
Hypersensitivity, Delayed
Demonstration of delayed hypersensitivity in Chlamydia trachomatis salpingitis in monkeys: a pathogenic mechanism of tubal damage.
Hypertension
15-Hydroxyeicosatetraenoic acid (15-HETE) protects pulmonary artery smooth muscle cells against apoptosis via HSP90.
Hypertension
Activation of heat shock transcription factor 1 in rat aorta in response to high blood pressure.
Hypertension
Acute hypertension induces heat-shock protein 70 gene expression in rat aorta.
Hypertension
Angiotensin II AT1 receptor blockade abolishes brain microvascular inflammation and heat shock protein responses in hypertensive rats.
Hypertension
Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease: evidence for an autoimmune component of atherogenesis.
Hypertension
Association of elevated serum heat-shock protein 70 concentration with transient hypertension of pregnancy, preeclampsia and superimposed preeclampsia: a case-control study.
Hypertension
Association of polymorphisms of THBS2 and HSPA8 with hypertension in Japanese individuals with chronic kidney disease.
Hypertension
Atherosclerosis--an autoimmune disease due to an immune reaction against heat-shock protein 60.
Hypertension
Autoimmunity in the pathogenesis of hypertension.
Hypertension
Circulating heat shock protein 60 is associated with early cardiovascular disease.
Hypertension
Circulating heat shock protein and heat shock protein antibody levels in established hypertension.
Hypertension
COVID-19 and hypertension: is the HSP60 culprit for the severe course and worse outcome?
Hypertension
Elevated heat shock protein 60 levels are associated with higher risk of coronary heart disease in Chinese.
Hypertension
Endoplasmic reticulum stress inhibition blunts the development of essential hypertension in the spontaneously hypertensive rat.
Hypertension
Failure of the heat-shock protein 70 locus to cosegregate with blood pressure in spontaneously hypertensive rat x Wistar-Kyoto rat cross.
Hypertension
Heat shock protein 60 involvement in vascular smooth muscle cell proliferation.
Hypertension
Heat shock protein 72 in cardiac and skeletal muscles during hypertension.
Hypertension
Heat shock protein expression in hearts hypertrophied by genetic and nongenetic hypertension.
Hypertension
Heat Shock Protein HSP60 in Left Ventricular Cardiomyocytes of Hypertensive Rats with and without Insulin-Dependent Diabetes Mellitus.
Hypertension
Heat shock proteins and the kidney.
Hypertension
Heat stress genes in hypertension.
Hypertension
HSP27 locus cosegregates with left ventricular mass independently of blood pressure.
Hypertension
HSP60, oxidative stress parameters and cardiometabolic risk markers in hypertensive and normotensive Slovak females.
Hypertension
Hypothesis to explain poor outcomes in the ALLHAT and V-HeFT trials: decreased expression of heat shock proteins.
Hypertension
Immune reactivity to heat shock protein 70 expressed in the kidney is cause of salt-sensitive hypertension.
Hypertension
Inhibition of heat shock protein 90 improves pulmonary arteriole remodeling in pulmonary arterial hypertension.
Hypertension
Inhibitory effect of Hsp70 on angiotensin II-induced vascular smooth muscle cell hypertrophy.
Hypertension
Interacting contribution of the five polymorphisms in three genes of Hsp70 family to essential hypertension in Uygur ethnicity.
Hypertension
Interaction of heat shock protein 70 (HSP70) polymorphisms and occupational hazards increases the risk of hypertension in coke oven workers.
Hypertension
Lessons from Cancer: Subcellular Drug Targeting of Mitochondrial Hsp90 in Pulmonary Arterial Hypertension.
Hypertension
Metolazone upregulates mitochondrial chaperones and extends lifespan in Caenorhabditis elegans.
Hypertension
Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
Hypertension
Myocardial hypoperfusion/reperfusion tolerance with exercise training in hypertension.
Hypertension
New Insights Into Heat Shock Protein 90 in the Pathogenesis of Pulmonary Arterial Hypertension.
Hypertension
PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes.
Hypertension
Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension.
Hypertension
Targeting HSP90 attenuates angiotensin II-induced adventitial remodeling via suppression of mitochondrial fission.
Hypertension
The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions?
Hypertension
The discovery of hypertension: evolving views on the role of the kidneys, and current hot topics.
Hypertension
Upregulation of GRP78 and caspase-12 in diastolic failing heart.
Hypertension
Vascular expression of heat shock protein 72 in fructose-induced hypertensive rats.
Hypertension
[Content of the major heat shock protein HSP70 in rats with hereditary stress-induced arterial hypertension]
Hypertension
[Preliminary study on relationship between antibody against heat stress protein 70 and hypertension]
Hypertension
[Relation of HSP70 gene and spontaneously hypertension in rats]
Hypertension
[Role of endoplasmic reticulum stress-related molecule GRP78 in global cerebral ischemia-reperfusion injury aggravated by hypertension in rats].
Hypertension
[The expression of heat shock protein 27 in retinal ganglion cells in the rat glaucoma model.]
Hypertension, Malignant
Expression of 90-kDa heat shock protein within regenerative tubular cells in a patient with acute oliguric renal failure due to malignant hypertension.
Hypertension, Portal
Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression.
Hypertension, Portal
Heat shock protein 90 is responsible for hyperdynamic circulation in portal hypertensive rats.
Hypertension, Portal
Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension.
Hypertension, Portal
Role of HSP-90 for increased nNOS-mediated vasodilation in mesenteric arteries in portal hypertension.
Hypertension, Pregnancy-Induced
Assessment of placental and maternal stress responses in patients with pregnancy related complications via monitoring of heat shock protein mRNA levels.
Hypertension, Pregnancy-Induced
Circulating heat shock protein mRNA profile in gestational hypertension, pre-eclampsia & foetal growth restriction.
Hypertension, Pulmonary
Beta-actin: a regulator of NOS-3.
Hypertension, Pulmonary
Decreased association of HSP90 impairs endothelial nitric oxide synthase in fetal lambs with persistent pulmonary hypertension.
Hypertension, Pulmonary
Diminished gene expression of cardiac heat shock proteins in pulmonary hypertensive chickens.
Hypertension, Pulmonary
Inducible HSP70 regulates superoxide dismutase-2 and mitochondrial oxidative stress in the endothelial cells from developing lungs.
Hypertension, Pulmonary
Nitric oxide and superoxide generation from endothelial NOS: modulation by HSP90.
Hypertension, Pulmonary
Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets.
Hypertension, Pulmonary
Variation of heat shock protein gene expression in the brain of cold-induced pulmonary hypertensive chickens.
Hypertension, Pulmonary
[Effect of heat shock protein 70 on pulmonary vascular remodeling in neonatal rats with hypoxic pulmonary hypertension].
Hypertension, Pulmonary
[Hypoxia stimulates the expression of HSP70 in pulmonary artery smooth muscle cells]
Hypertension, Pulmonary
[Protective effects of heat shock protein 70 against hypoxic pulmonary hypertension in neonatal rats].
Hyperthyroidism
Effect of thyroid hormone on mtHsp70 expression, mitochondrial import and processing in cardiac muscle.
Hyperthyroidism
Effects of thyroid hormone on ovarian cell apoptosis in the rat.
Hyperthyroidism
Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid Graves' disease.
Hyperthyroidism
Hyperthyroid hearts display a phenotype of cardioprotection against ischemic stress: a possible involvement of heat shock protein 70.
Hyperthyroidism
Investigation of the effect of hyperthyroidism on endoplasmic reticulum stress and tran- sient receptor potential canonical 1 channel in the kidney
Hypertrophy, Left Ventricular
Left ventricular hypertrophy is associated with overexpression of HSP60, TLR2, and TLR4 in the myocardium.
Hypertrophy, Left Ventricular
The Protective Effect of Lacidipine on Myocardial Remodeling Is Mediated by the Suppression in Expression of GPR78 and CHOP in Rats.
Hypertrophy, Right Ventricular
[The role of endoplasmic reticulum stress in pulmonary hypertension in rat induced by chronic hypoxia and hypercapnia].
Hypoalbuminemia
The role of albumin and endoplasmic reticulum in pathogenesis Preeclampsia. Changes of GRP78 and placental VEGF in preeclampsia.
Hypoglycemia
Amelioration of hypoxic and hypoglycemic damage to cerebral endothelial cells. Effects of heat shock pretreatment.
Hypoglycemia
Constitutively active heat shock factor 1 enhances glucose-driven insulin secretion.
Hypoglycemia
Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions.
Hypoglycemia
Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
Hypoglycemia
Expression of glucose-regulated proteins (GRP78 and GRP94) in hearts and fore-limb buds of mouse embryos exposed to hypoglycemia in vitro.
Hypoglycemia
Glucose-regulated protein 78 (GRP78) is elevated in embryonic mouse heart and induced following hypoglycemic stress.
Hypoglycemia
Hypoglycemia enhances the expression of prion protein and heat-shock protein 70 in a mouse neuroblastoma cell line.
Hypoglycemia
Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I.
Hypokalemic Periodic Paralysis
Expression of heat shock protein epitopes in tubular aggregates.
Hyponatremia
Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition.
Hypoparathyroidism
Ahsa1 and Hsp90 activity confers more severe craniofacial phenotypes in a zebrafish model of hypoparathyroidism, sensorineural deafness and renal dysplasia (HDR).
Hypopharyngeal Neoplasms
Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia.
Hypotension
Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
Hypotension
Heat shock protein 72 may improve hypotension by increasing cardiac mechanical efficiency and arterial elastance in heatstroke rats.
Hypotension
Oxidative stress and ischemic injuries in heat stroke.
Hypotension
Pathogenesis of an experimental heatstroke model.
Hypotension
Potentiation of baroreceptor reflex response by heat shock protein 70 in nucleus tractus solitarii confers cardiovascular protection during heatstroke.
Hypotension
Progressive exercise preconditioning protects against circulatory shock during experimental heatstroke.
Hypothyroidism
Effects of hypothyroidism and aortic construction on mitochondria during cardiac hypertrophy.
Hypothyroidism
Effects of thyroid hormone on ovarian cell apoptosis in the rat.
Hypothyroidism
Hypothyroidism selectively reduces the rate and amount of transport for specific SCb proteins in the hyt/hyt mouse optic nerve.
Hypoxia, Brain
Early diffusion weighted imaging and expression of heat shock protein 70 in newborn pigs with hypoxic ischaemic encephalopathy.
Idiopathic Pulmonary Fibrosis
A Fit-for-Purpose Method for the Detection of Human Antibodies to Surface-Exposed Components of BMS-986263, a Lipid Nanoparticle-Based Drug Product Containing a siRNA Drug Substance.
Idiopathic Pulmonary Fibrosis
Alpha-defensin enhances expression of HSP47 and collagen-1 in human lung fibroblasts.
Idiopathic Pulmonary Fibrosis
Analysis of heat shock protein 70 gene polymorphisms Mexican patients with idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis.
Idiopathic Pulmonary Fibrosis
Heat shock protein-90 toward theranostics: a breath of fresh air in idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Heat shock protein: a hot topic in idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
HSP90 Inhibition and Modulation of the Proteome: Therapeutical Implications for Idiopathic Pulmonary Fibrosis (IPF).
Idiopathic Pulmonary Fibrosis
Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis.
Idiopathic Pulmonary Fibrosis
Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses.
Idiopathic Pulmonary Fibrosis
Screening of Inhibitors Targeting Heat Shock Protein 47 Involved in the Development of Idiopathic Pulmonary Fibrosis.
Idiopathic Pulmonary Fibrosis
Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis.
Immune System Diseases
Administration of heat shock protein 65 inhibits murine melanoma growth in vivo.
Immune System Diseases
Heat shock protein 70-2 and tumor necrosis factor-? gene polymorphisms in Chinese children with Henoch-Schönlein purpura.
Immune System Diseases
Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition.
Infarction, Middle Cerebral Artery
Comparative analysis of the neuroprotective effects of ginsenosides Rg1 and Rb1 extracted from Panax notoginseng against cerebral ischemia.
Infarction, Middle Cerebral Artery
Ferulic Acid Exerts Anti-apoptotic Effects against Ischemic Injury by Activating HSP70/Bcl-2- and HSP70/Autophagy-Mediated Signaling after Permanent Focal Cerebral Ischemia in Rats.
Infarction, Middle Cerebral Artery
HSP27 Protects the Blood-Brain Barrier Against Ischemia-Induced Loss of Integrity.
Infarction, Middle Cerebral Artery
Hypothermia enhances heat-shock protein 70 production in ischemic brains.
Infarction, Middle Cerebral Artery
Induction of heat shock protein 40 and GrpE mRNAs following transient focal cerebral ischemia in the rat.
Infarction, Middle Cerebral Artery
Influence of electroacupuncture on the mRNA of heat shock protein 70 and 90 in brain after cerebral ischemia/reperfusion of rats.
Infarction, Middle Cerebral Artery
Mitochondrial serine protease Omi/HtrA2 accentuates brain ischemia/reperfusion injury in rats and oxidative stress injury in vitro by modulating mitochondrial stress proteins CHOP and ClpP and physically interacting with mitochondrial fusion protein OPA1.
Infarction, Middle Cerebral Artery
Modest MRI signal intensity changes precede delayed cortical necrosis after transient focal ischemia in the rat.
Infarction, Middle Cerebral Artery
Neuronal survival is associated with 72-kDa heat shock protein expression after transient middle cerebral artery occlusion in the rat.
Infarction, Middle Cerebral Artery
NO-induced downregulation of HSP10 and HSP60 expression in the postischemic brain.
Infarction, Middle Cerebral Artery
Occurrence of heat shock response in deafferented neurons in the substantia nigra of rats.
Infarction, Middle Cerebral Artery
Phosphorylated recombinant HSP27 protects the brain and attenuates blood-brain barrier disruption following stroke in mice receiving intravenous tissue-plasminogen activator.
Infarction, Middle Cerebral Artery
Resveratrol preconditioning induces cellular stress proteins and is mediated via NMDA and estrogen receptors.
Infarction, Middle Cerebral Artery
Temporal Profiles of Stress Protein Inductions after Focal Transient Ischemia in Mice Brain.
Infarction, Middle Cerebral Artery
The influence of delayed postischemic hyperthermia following transient focal ischemia: alterations of gene expression.
Infarction, Middle Cerebral Artery
[Effects of Naomaitong Recipe on expressions of nuclear factor-kappaB and nitric-oxide synthases in brain tissue after focal cerebral ischemia reperfusion in aged rats.]
Infections
A cellular protein related to heat-shock protein 90 accumulates during herpes simplex virus infection and is overexpressed in transformed cells.
Infections
A Class II small heat shock protein OsHsp18.0 plays positive roles in both biotic and abiotic defense responses in rice.
Infections
A comparative analysis of the products of GROEL-1 gene from Chlamydia trachomatis serovar D and the HSP60 var1 transcript from Homo sapiens suggests a possible autoimmune response.
Infections
A hypothetical model of crossing Bombyx mori nucleopolyhedrovirus through its host midgut physical barrier.
Infections
A mucosal subunit vaccine protects against lethal respiratory infection with Francisella tularensis LVS.
Infections
A Mycobacterium tuberculosis mutant lacking the groEL homologue cpn60.1 is viable but fails to induce an inflammatory response in animal models of infection.
Infections
A new role for heat shock factor 27 in the pathophysiology of Clostridium difficile toxin B.
Infections
A quantitative assay method of Toxoplasma gondii HSP70 mRNA by quantitative competitive-reverse transcriptase-PCR.
Infections
A relationship between serological markers of chronic C. pneumoniae and CMV infection and hsp60 in patients with atherosclerotic carotid stenosis.
Infections
A review of recent patents on the protozoan parasite HSP90 as a drug target.
Infections
A simple and rapid method for the purification of GroEL, an Escherichia coli homolog of the heat shock protein 60 family of molecular chaperonins.
Infections
A virulence factor of Helicobacter pylori: role of heat shock protein in mucosal inflammation after H. pylori infection.
Infections
Activation of c-Jun N-terminal kinase by Akabane virus is required for apoptosis.
Infections
Activation of c-jun N-terminal kinase upon influenza A virus (IAV) infection is independent of pathogen-related receptors but dependent on amino acid sequence variations of IAV NS1.
Infections
Activation of T cells recognizing an epitope of heat-shock protein 70 can protect against rat adjuvant arthritis.
Infections
Activation of the mitogen-activated protein kinase p38 by human cytomegalovirus infection through two distinct pathways: a novel mechanism for activation of p38.
Infections
Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes.
Infections
Acute infection of Sindbis virus induces phosphorylation and intracellular translocation of small heat shock protein HSP27 and activation of p38 MAP kinase signaling pathway.
Infections
Aeromonas hydrophila infection in silver catfish causes hyperlocomotion related to stress.
Infections
Aggregate-reactivation activity of the molecular chaperone ClpB from Ehrlichia chaffeensis.
Infections
Airflow limitation, asthma, and Chlamydia pneumoniae-specific heat shock protein 60.
Infections
An assay combining cell culture with reverse transcriptase PCR to detect and determine the infectivity of waterborne Cryptosporidium parvum.
Infections
An ELISA using recombinant TmHSP70 for the diagnosis of Taenia multiceps infections in goats.
Infections
An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain.
Infections
Analysis of Caenorhabditis elegans phosphoproteome reveals the involvement of a molecular chaperone, HSP-90 protein during Salmonella enterica Serovar Typhi infection.
Infections
Analysis of Chlamydia pneumoniae growth in cells by reverse transcription-PCR targeted to bacterial gene transcripts.
Infections
Analysis of heat shock protein 60 encoding genes of mycoplasmas and investigations concerning their role in immunity and infection.
Infections
Analysis of heat-induced changes in protein expression of Stenotrophomonas maltophilia K279a reveals a role for GroEL in the host-temperature adaptation.
Infections
Analysis of porcine differential gene expression following challenge with Salmonella enterica serovar Choleraesuis using suppression subtractive hybridization.
Infections
Analysis of the humoral immune response against total and recombinant antigens of Leishmania infantum: correlation with disease progression in canine experimental leishmaniasis.
Infections
Analysis of the Mycobacterium bovis hsp60 promoter activity in recombinant Mycobacterium avium.
Infections
Anaplasma marginale infection in a Japanese Black cow 13 years after eradication of Rhipicephalus (Boophilus) microplus in Okinawa, Japan.
Infections
Anaplasma phagocytophilum MSP4 and HSP70 Proteins Are Involved in Interactions with Host Cells during Pathogen Infection.
Infections
Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment.
Infections
Antibodies specific for heat shock proteins in human and murine malaria.
Infections
Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease: evidence for an autoimmune component of atherogenesis.
Infections
Antibody response to GroEL varies in patients with acute Mycoplasma pneumoniae infection.
Infections
Antibody to Mycobacterium tuberculosis 65 kDa heat shock protein in patients with rheumatoid arthritis--a survey of antigen-specific antibody isotypes and subclasses in an endemic area of previous tuberculosis infection.
Infections
Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses.
Infections
Antiviral and Anti-Inflammatory Activities of Pochonin D, a Heat Shock Protein 90 Inhibitor, against Rhinovirus Infection.
Infections
Aquatic birnavirus-induced ER stress-mediated death signaling contribute to downregulation of Bcl-2 family proteins in salmon embryo cells.
Infections
AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78.
Infections
Assessment of Apical Expression of Alpha-2 Integrin, Heat Shock Protein, and Proinflammatory and Immunoregulatory Cytokines in Response to Endodontic Infection.
Infections
Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk.
Infections
Astragalus polysaccharides attenuate PCV2 infection by inhibiting endoplasmic reticulum stress in vivo and in vitro.
Infections
Attenuated aroA Salmonella enterica serovar Typhimurium does not induce inflammatory response and early protection of gnotobiotic pigs against parental virulent LT2 strain.
Infections
Autoantibodies to a specific peptide epitope of human Hsp60 (ATVLA) with homology to Helicobacter pylori HspB in H. pylori-infected patients.
Infections
Autographa californica nucleopolyhedrovirus infection of Spodoptera frugiperda cells: a global analysis of host gene regulation during infection, using a differential display approach.
Infections
Autoimmune diseases and Helicobacter pylori infection.
Infections
Autoimmunity to human heat shock protein 60, Chlamydia pneumoniae infection, and inflammation in predicting coronary risk.
Infections
Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity.
Infections
Autophagy is involved in regulating influenza A virus RNA and protein synthesis associated with both modulation of Hsp90 induction and mTOR/p70S6K signaling pathway.
Infections
Autophagy machinery promotes the chaperone-mediated formation and compartmentalization of protein aggregates during appressorium development by the rice blast fungus.
Infections
Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.
Infections
Bacteriophage phi 105clz induces the GroEL-homologue protein in Bacillus subtilis.
Infections
Bag2 Is a Component of a Cytosolic Extraction Machinery That Promotes Membrane Penetration of a Nonenveloped Virus.
Infections
Bartonella bacilliformis GroEL: Effect on Growth of Human Vascular Endothelial Cells in Infected Cocultures.
Infections
Bartonella strains from ground squirrels are identical to Bartonella washoensis isolated from a human patient.
Infections
Betanodavirus up-regulates chaperone GRP78 via ER stress: roles of GRP78 in viral replication and host mitochondria-mediated cell death.
Infections
Bombyx mori cell division cycle protein 37 promotes the proliferation of BmNPV.
Infections
Borrelia burgdorferi Surface Exposed GroEL Is a Multifunctional Protein.
Infections
Caprine humoral response to Burkholderia pseudomallei antigens during acute melioidosis from aerosol exposure.
Infections
Capsid protein-mediated recruitment of host DnaJ-like proteins is required for Potato virus Y infection in tobacco plants.
Infections
Carotenoid-based plumage colouration is associated with blood parasite richness and stress protein levels in blue tits (Cyanistes caeruleus).
Infections
CD4(+) v(alpha)14 NKT cells play a crucial role in an early stage of protective immunity against infection with Leishmania major.
Infections
Cell type-specific variations in the induction of hsp70 in human leukocytes by feverlike whole body hyperthermia.
Infections
Cellular and molecular regulation of vaccination with heat shock protein 60 from Histoplasma capsulatum.
Infections
Changes in the proteome of pad2-1, a glutathione depleted Arabidopsis mutant, during Pseudomonas syringae infection.
Infections
Chaperone fusion proteins aid entropy-driven maturation of class II viral fusion proteins.
Infections
Chaperonin GroEL: a novel phylogenetically conserved protein with strong immunoreactivity of Avian Pathogenic Escherichia coli isolates from duck identified by immunoproteomics.
Infections
Characterization of Anaplasma spp. infection in dogs from Costa Rica.
Infections
Characterization of the main immunogenic proteins in Brucella infection for their application in diagnosis of brucellosis.
Infections
Characterization of the molecular chaperone ClpB from the pathogenic spirochaete Leptospira interrogans.
Infections
Chemotherapeutic potential of 17-AAG against cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis.
Infections
Chicken heat shock protein 90 is a component of the putative cellular receptor complex of infectious bursal disease virus.
Infections
Chlamydia pneumoniae heat shock protein 60 enhances expression of ERK, TLR-4 and IL-8 in atheromatous plaques of coronary artery disease patients.
Infections
Chlamydia pneumoniae infection acts as an endothelial stressor with the potential to initiate the earliest heat shock protein 60-dependent inflammatory stage of atherosclerosis.
Infections
Chlamydia pneumoniae infection of alveolar macrophages: a model.
Infections
Chlamydia pneumoniae stimulates proliferation of vascular smooth muscle cells through induction of endogenous heat shock protein 60.
Infections
Chlamydia pneumoniae, heat shock proteins 60 and risk of secondary cardiovascular events in patients with coronary heart disease under special consideration of diabetes : a prospective study.
Infections
Chlamydia trachomatis Infection Is Related to Poor Semen Quality in Young Prostatitis Patients.
Infections
Chlamydia trachomatis: The persistent pathogen.
Infections
Chlamydial antibodies in patients with previous acute anterior uveitis.
Infections
Chlamydial serology: comparative diagnostic value of immunoblotting, microimmunofluorescence test, and immunoassays using different recombinant proteins as antigens.
Infections
Chlamydophila pneumoniae infection leads to smooth muscle cell proliferation and thickening in the coronary artery without contributions from a host immune response.
Infections
Circulating antibodies to the 60-kD heat shock protein (hsp) family in patients with Helicobacter pylori infection.
Infections
Circulating heat shock protein 70 (Hsp70) in elderly members of a rural population from Cameroon: Association with infection and nutrition.
Infections
Circulating heat shock proteins in women with a history of recurrent vulvovaginitis.
Infections
Circulating heat-shock protein 70 is associated with postoperative infection and organ dysfunction after liver resection.
Infections
Clinical Consequences of Immune Response to CT Upper Genital Tract Infection in Women.
Infections
Cloning and kinetics of expression of Brucella abortus heat shock proteins by baculovirus recombinants.
Infections
Cloning of Hsp21 gene and its expression in Chinese shrimp Fenneropenaeus chinensis in response to WSSV challenge.
Infections
Cloning, expression and characterization of heat shock protein 60 (groEL) of Salmonella enterica serovar Typhi and its role in protective immunity against lethal Salmonella infection in mice.
Infections
Cloning, purification and characterization of a 90kDa heat shock protein from Citrus sinensis (sweet orange).
Infections
Co-expression of S. Typhi GroEL and IL-22 gene augments immune responses against Salmonella infection.
Infections
Combined treatments with interferon (alpha,beta) plus PGA1 to control early infection with HTLV-I in primary cord blood-derived mononuclear cells.
Infections
Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei.
Infections
Comparative analysis of differential gene expression of HSP40 and HSP70 family isoforms during heat stress and HIV-1 infection in T-cells.
Infections
Comparison of PCR methods for detection of Leishmania siamensis infection.
Infections
Comparison of Recombinant Proteins of Kinesin 39, Heat Shock Protein 70, Heat Shock Protein 83 and Glycoprotein 63 for Antibody Detection of Leishmania martiniquensis Infection.
Infections
Complex spatial responses to cucumber mosaic virus infection in susceptible Cucurbita pepo cotyledons.
Infections
Conservation of Babesia bovis small heat shock protein (Hsp20) among strains and definition of T helper cell epitopes recognized by cattle with diverse major histocompatibility complex class II haplotypes.
Infections
Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells.
Infections
Construction of recombinant neisserial Hsp60 proteins and mapping of antigenic domains.
Infections
Construction, expression and identification of a recombinant BCG vaccine encoding human mycobacterium tuberculosis heat shock protein 65.
Infections
Contribution of 65-kDa heat shock protein induced by gamma and delta T cells to protection against Toxoplasma gondii infection.
Infections
Contribution of anti-Hsp70.1 IgG antibody levels to the diagnostic certainty of clinically suspected ocular toxoplasmosis.
Infections
Correction: Heat shock protein 90 positively regulates chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infection.
Infections
Cross-reactive antigens shared by Pseudomonas aeruginosa, Helicobacter pylori, Campylobacter jejuni, and Haemophilus influenzae may cause false-positive titers of antibody to H. pylori.
Infections
CSFV Infection Up-Regulates the Unfolded Protein Response to Promote Its Replication.
Infections
CSFV protein NS5A activates the unfolded protein response to promote viral replication.
Infections
Cucumber Necrosis Virus Recruits Cellular Heat Shock Protein 70 Homologs at Several Stages of Infection.
Infections
Current progress in proteomic study of hepatitis C virus-related human hepatocellular carcinoma.
Infections
Cutaneous leishmaniasis caused by Leishmania donovani in the tribal population of the Agasthyamala Biosphere Reserve forest, Western Ghats, Kerala, India.
Infections
Cytokine and estrogen stimulation of endothelial cells augments activation of the prekallikrein-high molecular weight kininogen complex: Implications for hereditary angioedema.
Infections
Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection.
Infections
Cytoskeletal Alteration Is an Early Cellular Response in Pulmonary Epithelium Infected with Aspergillus fumigatus Rather than Scedosporium apiospermum.
Infections
Demonstration of delayed hypersensitivity in Chlamydia trachomatis salpingitis in monkeys: a pathogenic mechanism of tubal damage.
Infections
Dengue virus entry into liver (HepG2) cells is independent of hsp90 and hsp70.
Infections
Dengue virus infection induces GRP78 which acts to chaperone viral antigen production.
Infections
Detection of candidal antigens in autoimmune polyglandular syndrome type I.
Infections
Detection of human pathogenic Ehrlichia muris-like agent in Peromyscus leucopus.
Infections
Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection.
Infections
Differences in structure and changes in gene regulation of murrel molecular chaperone HSP family during epizootic ulcerative syndrome (EUS) infection.
Infections
Does serologic evidence of remote Chlamydia trachomatis infection and its heat shock protein (CHSP 60) affect in vitro fertilization-embryo transfer outcome?
Infections
Duck enteritis virus infection suppresses viability and induces apoptosis and endoplasmic reticulum stress in duck embryo fibroblast cells via the regulation of Ca2.
Infections
Dynamics of heat shock protein 70 concentrations in peripheral blood lymphocyte lysates during pregnancy in lactating Holstein-Friesian cows.
Infections
Early antibody response and clinical outcome in experimental canine leishmaniasis.
Infections
Early appearing gamma/delta-bearing T cells during infection with Calmétte Guérin bacillus.
Infections
Effect of adjuvants on immune response and protective immunity elicited by recombinant Hsp60 (GroEL) of Salmonella typhi against S. typhi infection.
Infections
Effect of bacterial flora on postimmunization gastritis following oral vaccination of mice with Helicobacter pylori heat shock protein 60.
Infections
Effect of human papillomavirus infection on estrogen receptor and heat shock protein hsp27 phenotype in human cervix and vagina.
Infections
Effect of multiple microsporidian infections and temperature stress on the heat shock protein 70 (hsp70) response of the amphipod Gammarus pulex.
Infections
Effect of periodontal treatment on the serum antibody levels to heat shock proteins.
Infections
Effect of Staphylococcus aureus infection on the heat stress protein 70 (HSP70) level in chicken embryo tissues.
Infections
Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV-I. II. Regulation of synthesis of inducible p72 heat shock protein.
Infections
Effects of Helicobacter pylori and Heat Shock Protein 70 on the Proliferation of Human Gastric Epithelial Cells.
Infections
Effects of hesperidin on the growth performance, antioxidant capacity, immune responses and disease resistance of red swamp crayfish (Procambarus clarkii).
Infections
Effects of Mycobacterium tuberculosis Mutant Strain Hsp16.3 Gene on Murine RAW 264.7 Macrophage Autophagy.
Infections
Effects of repeated Chlamydia pneumoniae inoculations on aortic lipid accumulation and inflammatory response in C57BL/6J mice.
Infections
Elevated levels of Legionella pneumophila stress protein Hsp60 early in infection of human monocytes and L929 cells correlate with virulence.
Infections
Elevated serum heat-shock protein 70 levels in patients with acute infection: use of an optimized enzyme-linked immunosorbent assay.
Infections
Elucidation of the Inhibitory Mechanisms of Nipponoparmelia laevior Lichen Extract against Influenza A (H1N1) Virus through Proteomic Analyses.
Infections
Emerging cellular targets for influenza antiviral agents.
Infections
Endoplasmic reticulum chaperone gp96 is essential for infection with vesicular stomatitis virus.
Infections
Endoplasmic Reticulum Stress Aggravates Viral Myocarditis by Raising Inflammation Through the IRE1-Associated NF-?B Pathway.
Infections
Endoplasmic reticulum stress-mediated autophagy contributes to bluetongue virus infection via the PERK-eIF2? pathway.
Infections
Enhanced levels of Staphylococcus aureus stress protein GroEL and DnaK homologs early in infection of human epithelial cells.
Infections
Enhanced resistance against Vibrio harveyi infection by carvacrol and its association with the induction of heat shock protein 72 in gnotobiotic Artemia franciscana.
Infections
Epidemiology, genetic variants and clinical course of natural infections with Anaplasma phagocytophilum in a dairy cattle herd.
Infections
Epigenetic modulation, stress and plasticity in susceptibility of the snail host, Biomphalaria glabrata, to Schistosoma mansoni infection.
Infections
Epitopes of Immunoreactive Proteins of Streptococcus Agalactiae: Enolase, Inosine 5'-Monophosphate Dehydrogenase and Molecular Chaperone GroEL.
Infections
Escherichia coli grpE gene codes for heat shock protein B25.3, essential for both lambda DNA replication at all temperatures and host growth at high temperature.
Infections
Ethanol facilitates HCV replication via upregulation of GW182 and HSP90 in human hepatoma cells.
Infections
Eukaryotic heat shock proteins as molecular links in innate and adaptive immune responses: Hsp60-mediated activation of cytotoxic T cells.
Infections
Evaluation of Newcastle disease virus mediated dendritic cell activation and cross-priming tumor-specific immune responses ex vivo.
Infections
Evaluation of the recombinant Heat shock protein B (HspB) of Coxiella burnetii as a potential antigen for immunodiagnostic of Q fever in goats.
Infections
Evidence for disruption of Na(+)-K(+)-ATPase and hsp70 during vibriosis of sea bream, Sparus (=Rhabdosargus) sarba Forsskål.
Infections
Evidence for the early recruitment of T-cell receptor gamma delta+ T cells during rat listeriosis.
Infections
Exogenous heat shock protein 27 uniquely blocks differentiation of monocytes to dendritic cells.
Infections
Experimental cauda equina compression induces HSP70 synthesis in dog.
Infections
Experimental Trial with a Heat-Shocked Protoscolex Extract as a Vaccine Candidate for Protection Against Hydatid Disease.
Infections
Exposure of gnotobiotic Artemia franciscana larvae to abiotic stress promotes heat shock protein 70 synthesis and enhances resistance to pathogenic Vibrio campbellii.
Infections
Expression analysis of heat shock protein genes during Aeromonas hydrophila infection in rohu, Labeo rohita, with special reference to molecular characterization of Grp78.
Infections
Expression of 65- and 67-kilodalton heat-regulated proteins and a 70-kilodalton heat shock cognate protein of Leishmania donovani in macrophages.
Infections
Expression of Heat shock protein 70 (Hsp70-1) in Plasmodium berghei ookinetes and its participation in midgut mosquito infection.
Infections
Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost.
Infections
Expression of heat shock proteins and subolesin affects stress responses, Anaplasma phagocytophilum infection and questing behaviour in the tick, Ixodes scapularis.
Infections
Expression of Helicobacter pylori Hsp60 protein and its immunogenicity.
Infections
Expression of recombinant heat-shock protein 70 of MCAN/IR/96/LON-49, a tool for diagnosis and future vaccine research.
Infections
Expression pattern of heat-shock cognate 70 gene of humphead snapper, Lutjanus sanguineus (Cuvier), infected by Vibrio harveyi.
Infections
Expression Profiling of Plasmodium berghei HSP70 Genes for Generation of Bright Red Fluorescent Parasites.
Infections
Extracellular Hsp90 serves as a co-factor for MAPK activation and latent viral gene expression during de novo infection by KSHV.
Infections
Extracellular Hsp90 serves as a co-factor for NF-?B activation and cellular pathogenesis induced by an oncogenic herpesvirus.
Infections
Feeding Artemia franciscana (Kellogg) larvae with bacterial heat shock protein, protects from Vibrio campbellii infection.
Infections
First detection of the Anaplasma phagocytophilum groEL-A genotype in man.
Infections
Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling.
Infections
Formation of aggresome-like structures in herpes simplex virus type 2-infected cells and a potential role in virus assembly.
Infections
Frequency and Magnitude of Chlamydia trachomatis Elementary Body- and Heat Shock Protein 60-Stimulated Interferon gamma Responses in Peripheral Blood Mononuclear Cells and Endometrial Biopsy Samples from Women with High Exposure to Infection.
Infections
Frequency of antigen-specific B cells during experimental ocular Chlamydia trachomatis infection.
Infections
Functional role of Hsp60 as a positive regulator of human viral infection progression.
Infections
Functional roles of GRP78 in hepatitis B virus infectivity and antigen secretion.
Infections
Functional similarities between the small heat shock proteins Mycobacterium tuberculosis HSP 16.3 and human alphaB-crystallin.
Infections
Functional surface proteomic profiling reveals the host heat-shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages.
Infections
Fusobacterium nucleatum GroEL induces risk factors of atherosclerosis in human microvascular endothelial cells and ApoE(-/-) mice.
Infections
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.
Infections
Gene transfer into hippocampal slice cultures with an adenovirus vector driven by cytomegalovirus promoter: stable co-expression of green fluorescent protein and lacZ genes.
Infections
Genetic differences in the Chlamydia trachomatis tryptophan synthase alpha-subunit can explain variations in serovar pathogenesis.
Infections
Genetic diversity of groEL and msp4 sequences of Anaplasma ovis infecting camels from Tunisia.
Infections
Global Transcriptomic Analysis Reveals Insights into the Response of 'Etrog' Citron (Citrus medica L.) to Citrus Exocortis Viroid Infection.
Infections
Glucose-regulated protein 78 is an antiviral against hepatitis A virus replication.
Infections
Glucose-Regulated Protein 78 Is an Intracellular Antiviral Factor against Hepatitis B Virus.
Infections
GroEL protein of the Leptospira spp. interacts with host proteins and induces cytokines secretion on macrophages.
Infections
GroEL provides protection against Bacillus anthracis infection in BALB/c mice.
Infections
GRP78, a coreceptor for coxsackievirus A9, interacts with major histocompatibility complex class I molecules which mediate virus internalization.
Infections
Habitat effects on physiological stress response in nestling blue tits are mediated through parasitism.
Infections
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.
Infections
Heat shock protein 70 (HSP70) in gastric adaptation to aspirin in Helicobacter pylori infection.
Infections
Heat shock cognate 70 gene in Haliotis diversicolor: responses to pathogen infection and environmental stresses and its transcriptional regulation analysis.
Infections
Heat shock cognate 70 is a prominent immunogen in Brugian filariasis.
Infections
Heat shock cognate protein 70 contributes to Brucella invasion into trophoblast giant cells that cause infectious abortion.
Infections
Heat shock cognate protein 70 gene is required for prevention of apoptosis induced by WSSV infection.
Infections
Heat shock cognate protein 70 is a cell fusion-enhancing factor but not an entry factor for human T-cell lymphotropic virus type I.
Infections
Heat shock cognate protein 70 isoform D is required for clathrin-dependent endocytosis of Japanese encephalitis virus in C6/36cells.
Infections
Heat shock protein 20 from Procambarus clarkii is involved in the innate immune responses against microbial infection.
Infections
Heat shock protein 27 is involved in PCV2 infection in PK-15 cells.
Infections
Heat shock protein 60 and immune inflammatory responses in atherosclerosis.
Infections
Heat shock protein 60 autoimmunity and early lipid lesions in cholesterol-fed C57BL/6JBom mice during Chlamydia pneumoniae infection.
Infections
Heat shock protein 60 specific T-cell response in chlamydial infections.
Infections
Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation.
Infections
Heat Shock Protein 60, Insights to Its Importance in Histoplasma capsulatum: From Biofilm Formation to Host-Interaction.
Infections
Heat shock protein 65 induced by gammadelta T cells prevents apoptosis of macrophages and contributes to host defense in mice infected with Toxoplasma gondii.
Infections
Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells.
Infections
Heat shock protein 70 as a supplementary receptor facilitates enterovirus 71 infections in vitro.
Infections
Heat shock protein 70 from Litopenaeus vannamei (LvHSP70) is involved in the innate immune response against white spot syndrome virus (WSSV) infection.
Infections
Heat shock protein 70 from Trichinella spiralis induces protective immunity in BALB/c mice by activating dendritic cells.
Infections
Heat shock protein 70 is a potential virulence factor in murine toxoplasma infection via immunomodulation of host NF-kappa B and nitric oxide.
Infections
Heat Shock Protein 70 Messenger RNA in Rat Leukocytes Elevates After Severe Intestinal Ischemia-Reperfusion.
Infections
Heat shock protein 70 promotes coxsackievirus B3 translation initiation and elongation via Akt-mTORC1 pathway depending on activation of p70S6K and Cdc2.
Infections
Heat shock protein 72 (HSPA1B) gene polymorphism and Toll-like receptor (TLR) 4 mutation are associated with increased risk of urinary tract infection in children.
Infections
Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells.
Infections
Heat Shock Protein 90 Chaperones E1A Early Protein of Adenovirus 5 and Is Essential for Replication of the Virus.
Infections
Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans.
Infections
Heat Shock Protein 90 of Bonamia ostreae: Characterization and Possible Correlation with Infection of the Flat Oyster, Ostrea edulis.
Infections
Heat shock protein 90 positively regulates Chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infection.
Infections
Heat Shock protein 90: Role in Enterovirus 71 Entry and Assembly and Potential Target for Therapy.
Infections
Heat Shock Protein A6, a Novel HSP70, Is Induced During Enterovirus A71 Infection to Facilitate Internal Ribosomal Entry Site-Mediated Translation.
Infections
Heat shock protein and heat shock factor 1 expression and localization in vaccinia virus infected human monocyte derived macrophages.
Infections
Heat shock protein expression and immunity in chlamydial infections.
Infections
Heat shock protein inhibitors increase the efficacy of measles virotherapy.
Infections
Heat Shock Protein Member 8 Is an Attachment Factor for Infectious Bronchitis Virus.
Infections
Heat shock protein profiles on the protein and gene expression levels in olive flounder kidney infected with Streptococcus parauberis.
Infections
Heat shock proteins (HSP 90, 70, 60, and 27) in Galleria mellonella (Lepidoptera) hemolymph are affected by infection with Conidiobolus coronatus (Entomophthorales).
Infections
Heat shock proteins protect platyfish (Xiphophorus maculatus) from Yersinia ruckeri induced mortality.
Infections
Heat-shock protein 60 and cardiovascular disease: a paradoxical role.
Infections
Heat-shock protein 90 promotes nuclear transport of herpes simplex virus 1 capsid protein by interacting with acetylated tubulin.
Infections
Heat-shock protein 90? is involved in maintaining the stability of VP16 and VP16-mediated transactivation of ? genes from herpes simplex virus-1.
Infections
Helicobacter pylori and cardiovascular disease: update 2019.
Infections
Helicobacter pylori and gastric epithelial cells: from gastritis to cancer.
Infections
Helicobacter pylori infection in connective tissue disorders is associated with high levels of antibodies to mycobacterial hsp65 but not to human hsp60.
Infections
Helicobacter pylori-derived heat shock protein 60 increases the induction of regulatory T-cells associated with persistent infection.
Infections
Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response.
Infections
Hepatitis B virus enhances cisplatin-induced hepatotoxicity via a mechanism involving suppression of glucose-regulated protein of 78 Kda.
Infections
Herpes simplex virus Us11 protein enhances recovery of protein synthesis and survival in heat shock treated HeLa cells.
Infections
Herpes simplex virus-induced expression of 70 kDa heat shock protein (HSP70) requires early protein synthesis but not viral DNA replication.
Infections
HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Infections
High affinity binding between Hsp70 and the C-terminal domain of the measles virus nucleoprotein requires an Hsp40 co-chaperone.
Infections
High doses of sodium ascorbate act as a prooxidant and protect gnotobiotic brine shrimp larvae (Artemia franciscana) against Vibrio harveyi infection coinciding with heat shock protein 70 activation.
Infections
High GRP78 levels in Covid-19 infection: A case-control study.
Infections
High-throughput screening fluorescence polarization assay for tumor-specific hsp90.
Infections
Host cell responses to Listeria monocytogenes infection include differential transcription of host stress genes involved in signal transduction.
Infections
Host factor heat-shock protein 90 contributes to baculovirus budded virus morphogenesis via facilitating nuclear actin polymerization.
Infections
Host protein, HSP90?, antagonizes IFN-? signaling pathway and facilitates the proliferation of encephalomyocarditis virus in vitro.
Infections
HPV genotypes distribution in Chlamydia trachomatis co-infection in a large cohort of women from North-East Italy.
Infections
Hsc70 Focus Formation at the Periphery of HSV-1 Transcription Sites Requires ICP27.
Infections
HSC70 interactions with SV40 viral proteins differ between permissive and nonpermissive mammalian cells.
Infections
Hsc70 is a Component of Bacterially Generated Actin-Rich Structures: An Immunolocalization Study.
Infections
HSC70 is required for infectious bursal disease virus (IBDV) infection in DF-1 cells.
Infections
Hsc70 regulates the IRES activity and serves as an antiviral target of enterovirus A71 infection.
Infections
Hsp27 Responds to and Facilitates Enterovirus A71 Replication by Enhancing Viral Internal Ribosome Entry Site-Mediated Translation.
Infections
HSP60 and anti-HSP60 antibodies in vasculitis: they are two of a kind.
Infections
HSP60 and HSP90? from blunt snout bream, Megalobrama amblycephala: Molecular cloning, characterization, and comparative response to intermittent thermal stress and Aeromonas hydrophila infection.
Infections
HSP60 critically regulates endogenous IL-1? production in activated microglia by stimulating NLRP3 inflammasome pathway.
Infections
Hsp60 specific antibodies in egg yolks from laying hens naturally infected with Salmonella enterica subspecies enterica serovar Enteritidis.
Infections
hsp70 and a novel axis of type I interferon-dependent antiviral immunity in the measles virus-infected brain.
Infections
HSP70 Overexpression in Response to Ureaplasma urealyticum-Mediated Oxidative Stress In Preeclamptic Placenta.
Infections
hsp70 synthesis in Schwann cells in response to heat shock and infection with Mycobacterium leprae.
Infections
Hsp70-1: upregulation via selective phosphorylation of heat shock factor 1 during coxsackieviral infection and promotion of viral replication via the AU-rich element.
Infections
hsp70-Dependent Antiviral Immunity against Cytopathic Neuronal Infection by Vesicular Stomatitis Virus.
Infections
HSP70/DNAJA3 chaperone/cochaperone regulates NF-?B activity in immune responses.
Infections
HSP90 and co-chaperones: a multitaskers' view on plant hormone biology.
Infections
Hsp90 function is required for stable transcription of the baculovirus transactivator ie-1 gene.
Infections
Hsp90 governs dispersion and drug resistance of fungal biofilms.
Infections
Hsp90 inhibitor AT-533 blocks HSV-1 nuclear egress and assembly.
Infections
Hsp90 inhibitor reduces porcine circovirus 2 replication in the porcine monocytic line 3D4/31.
Infections
Hsp90 Inhibitors Exhibit Resistance-Free Antiviral Activity against Respiratory Syncytial Virus.
Infections
Hsp90 inhibitors reduce influenza virus replication in cell culture.
Infections
Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice.
Infections
Hsp90 interacts with multiple dengue virus 2 proteins.
Infections
Hsp90 is essential in the filarial nematode Brugia pahangi.
Infections
Hsp90, Hsp60 and sHsp families of heat shock protein genes in channel catfish and their expression after bacterial infections.
Infections
Hsp90/Sec22b promotes unconventional secretion of mature-IL-1? through an autophagosomal carrier in porcine alveolar macrophages during Mycoplasma hyopneumoniae infection.
Infections
Hsp90: a chaperone for HIV-1.
Infections
Human antibody responses to Trypanosoma cruzi 70-kD heat-shock proteins.
Infections
Human Cytomegalovirus Stimulates Monocyte-to-Macrophage Differentiation via the Temporal Regulation of Caspase 3.
Infections
Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins.
Infections
Human Hsp60: bacterial expression, purification, development of monoclonal antibodies and a sandwich ELISA for quantitation.
Infections
Human Metapneumovirus Impairs Apoptosis of Nasal Epithelial Cells in Asthma via HSP70.
Infections
Human T-cell clones to the 70-kilodalton heat shock protein of Mycobacterium leprae define mycobacterium-specific epitopes rather than shared epitopes.
Infections
Humoral immune response to conserved epitopes of Chlamydia trachomatis and human 60-kDa heat-shock protein in women with pelvic inflammatory disease.
Infections
ICP27 phosphorylation site mutants are defective in herpes simplex virus 1 replication and gene expression.
Infections
Identification and characterization of a DR4-restricted T cell epitope within chlamydia heat shock protein 60.
Infections
Identification of ?E-Dependent Promoter Upstream of clpB from the Pathogenic Spirochaete Leptospira interrogans by Applying an E. coli Two-Plasmid System.
Infections
Identification of autoantibodies with the corresponding antigen for repetitive coxsackievirus infection-induced cardiomyopathy.
Infections
Identification of Glucose-Regulated Protein 78 (GRP78) as a Receptor in BHK-21 Cells for Duck Tembusu Virus Infection.
Infections
Identification of GRP 78 (BiP) as a liver cell expressed receptor element for dengue virus serotype 2.
Infections
Identification of heat shock protein A9 as a Tembusu virus binding protein on DF-1 cells.
Infections
Identification of immunoreactive proteins of Chlamydia trachomatis by Western blot analysis of a two-dimensional electrophoresis map with patient sera.
Infections
Identification of in vivo-expressed immunogenic proteins by serological proteome analysis of the Bacillus anthracis secretome.
Infections
Identification of nontuberculous mycobacterial infection by IS6110 and hsp65 gene analysis on lung tissues.
Infections
Identification of rickettsial immunoreactive proteins using a proximity ligation assay Western blotting and the traditional immunoproteomic approach.
Infections
Identification of the resistance of a novel molecule heat shock protein 90alpha (HSP90alpha) in Microtus fortis to Schistosoma japonicum infection.
Infections
Identification of the small heat shock protein, HSP21, of shrimp Penaeus monodon and the gene expression of HSP21 is inactivated after white spot syndrome virus (WSSV) infection.
Infections
Identification of two mutation sites in spike and envelope proteins mediating optimal cellular infection of porcine epidemic diarrhea virus from different pathways.
Infections
Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication.
Infections
Immune recognition of human Hsp60 by Lyme disease patient sera.
Infections
Immune Recognition of the 60kD Heat Shock Protein: Implications for Subsequent Fertility.
Infections
Immune response against a cross-reactive epitope on the heat shock protein 60 homologue of Helicobacter pylori.
Infections
Immune response to heat shock protein of Helicobacter pylori--a candidate as a vaccine component.
Infections
Immune Responses Induced by HSP60 DNA Vaccine against Toxoplasma gondii Infection in Kunming Mice.
Infections
Immune Sensitization to the 60 kD Heat Shock Protein and Pregnancy Outcome.
Infections
Immunity against Yersinia enterocolitica by vaccination with Yersinia HSP60 immunostimulating complexes or Yersinia HSP60 plus interleukin-12.
Infections
Immunity to heat shock proteins and pregnancy outcome.
Infections
Immunization with Brugia malayi Hsp70 protects mice against Litomosoides sigmodontis challenge infection.
Infections
Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice.
Infections
Immunodetection of the recombinant GroEL by the Nanobody NbBruc02
Infections
Immunodetection of the recombinant GroEL by the Nanobody NbBruc02.
Infections
Immunogenicity and protective efficacy of GroEL (hsp60) of Streptococcus pneumoniae against lethal infection in mice.
Infections
Immunologic response enhances atherosclerosis-type 1 helper T cell (Th1)-to-type 2 helper T cell (Th2) shift and calcified atherosclerosis in Bacillus Calmette-Guerin (BCG)-treated apolipoprotein E-knockout (apo E-/-) mice.
Infections
Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment.
Infections
Impaired inducibility of heat shock protein 70 in peripheral blood lymphocytes of patients with severe sepsis.
Infections
Implication of heat shock proteins in rotavirus entry into Reh cells.
Infections
Implication of Hsc70, PDI and integrin ?v?3 involvement during entry of the murine rotavirus ECwt into small-intestinal villi of suckling mice.
Infections
Implications of antibodies to heat-shock proteins in ischemic heart disease.
Infections
Improvement of the production of GFPuv-beta1,3-N-acetylglucosaminyltransferase 2 fusion protein using a molecular chaperone-assisted insect-cell-based expression system.
Infections
In silico analysis of proteins and microRNAs related to human African trypanosomiasis in tsetse fly.
Infections
In silico identification of functional divergence between the multiple groEL gene paralogs in Chlamydiae.
Infections
In vitro interactions between 17-AAG and azoles against Exophiala dermatitidis.
Infections
In vivo and in vitro association of hsc70 with polyomavirus capsid proteins.
Infections
Increase in a heat-shock protein from blood cells in response of nestling house martins (Delichon urbica) to parasitism: an experimental approach.
Infections
Increased expression of 70 kD heat shock protein in cultured primary human keratinocytes induced by human papillomavirus 16 E6/E7 gene.
Infections
Increased expression of Gp96 by HBx-induced NF-?B activation feedback enhances hepatitis B virus production.
Infections
Increased expression of HDJ-2 (heat shock protein 40) and heat shock protein 70 in biopsy specimens of transplanted human lungs.
Infections
Increased intracellular, cell surface, and secreted inducible heat shock protein 70 responses are triggered during the monocyte to dendritic cell (DC) transition by cytokines independently of heat stress and infection and may positively regulate DC growth.
Infections
Increased risk of atherosclerosis is confined to CagA-positive Helicobacter pylori strains: prospective results from the Bruneck study.
Infections
Induction of cellular hsp70 expression by human cytomegalovirus.
Infections
Induction of heat shock protein 60 expression in human monocytic cell lines infected with Mycobacterium leprae.
Infections
Induction of heat shock protein closely correlates with protection against Toxoplasma gondii infection.
Infections
Induction of manganese-superoxide dismutase in MRC-5 cells persistently infected with an alphavirus, sindbis.
Infections
Induction of messenger RNA for the 70 kDa heat shock protein in HeLa cells and the human endocervix following exposure to semen: implications for antisperm antibody production and susceptibility to sexually transmitted infections.
Infections
Induction of oral tolerance as treatment or prevention of chronic diseases associated with Chlamydia pneumoniae infection--hypothesis.
Infections
Induction of pro-viral grass carp Ctenopharyngodon idella Hsp70 instead of Hsc70 during infection of grass carp reovirus.
Infections
Induction of secretion of interleukin-8 from human gastric epithelial cells by heat-shock protein 60 homologue of Helicobacter pylori.
Infections
Induction of SIV capsid-specific CTL and mucosal sIgA in mice immunized with a recombinant S. typhimurium aroA mutant.
Infections
Infection by ME7 prion is not modified in transgenic mice expressing the yeast chaperone Hsp104 in neurons.
Infections
Infection of human and murine macrophages with Leishmania major is associated with early parasite heat shock protein synthesis but fails to induce a host cell stress response.
Infections
Inflammation, heat shock proteins and periodontal pathogens in atherosclerosis: an immunohistologic study.
Infections
Influence of parasitization by Trichinella spiralis on the levels of heat shock proteins in rat liver and muscle.
Infections
Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.
Infections
Ingestion of bacteria overproducing DnaK attenuates Vibrio infection of Artemia franciscana larvae.
Infections
Inhibition of Calpain Alleviates Apoptosis in Coxsackievirus B3-induced Acute Virus Myocarditis Through Suppressing Endoplasmic Reticulum Stress.
Infections
Inhibition of heat-shock protein 90 enhances the susceptibility to antifungals and reduces the virulence of Cryptococcus neoformans/Cryptococcus gattii species complex.
Infections
Inhibition of heat-shock protein 90 reduces Ebola virus replication.
Infections
Inhibition of HSP90 and Activation of HSF1 Diminish Macrophage NLRP3 Inflammasome Activity in Alcohol-Associated Liver Injury.
Infections
Inhibition of HSP90 attenuates porcine reproductive and respiratory syndrome virus production in vitro.
Infections
Inhibition of infectious bursal disease virus infection by artificial miRNAs targeting the chicken heat shock protein 90.
Infections
Inhibition of rotavirus ECwt infection in ICR suckling mice by N-acetylcysteine, peroxisome proliferator-activated receptor gamma agonists and cyclooxygenase-2 inhibitors.
Infections
Inhibitory effect of Japanese rice-koji miso extracts on hepatitis A virus replication in association with the elevation of glucose-regulated protein 78 expression.
Infections
Initiation of the Immune Response by Extracellular Hsp72: Chaperokine Activity of Hsp72.
Infections
Innate immune gene expression in individual zebrafish after Listonella anguillarum inoculation.
Infections
Insights into Macrophage Autophagy in Latent Tuberculosis Infection: Role of Heat Shock Protein 16.3.
Infections
Interactive Responses of Potato (Solanum tuberosum L.) Plants to Heat Stress and Infection With Potato Virus Y.
Infections
Intra- and inter-breed variation in immune response to acute and sub-chronic Salmonella infection and commercial immune-stimulant in two-layer breeds.
Infections
Involvement of HSC70-4 and other inducible HSPs in Bombyx mori nucleopolyhedrovirus infection.
Infections
Irreversible UV inactivation of Cryptosporidium spp. despite the presence of UV repair genes.
Infections
Is chlamydial heat shock protein 60 a risk factor for oncogenesis?
Infections
Isolation and characterization of Heat Shock Protein 100-Batu1 from Toxoplasma gondii RH strain.
Infections
Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections.
Infections
Lack of association between the GRP78 polymorphisms in the promoter and 3' UTR and susceptibility to chronic HBV infection in a Chinese Han population.
Infections
LAP, an alcohol acetaldehyde dehydrogenase enzyme in Listeria, promotes bacterial adhesion to enterocyte-like Caco-2 cells only in pathogenic species.
Infections
Larvae Crowding Increases Development Rate, Improves Disease Resistance, and Induces Expression of Antioxidant Enzymes and Heat Shock Proteins in Mythimna separata (Lepidoptera: Noetuidae).
Infections
Leishmania major Hsp100 is required chiefly in the mammalian stage of the parasite.
Infections
Lipid raft microdomains: key sites for Coxsackievirus A9 infectious cycle.
Infections
Listeria monocytogenes Uses LAP to Promote Bacterial Transepithelial Translocation, and Induces Expression of LAP Receptor Hsp60.
Infections
Localization of sweet potato chlorotic stunt virus (SPCSV) in synergic infection with potyviruses in sweet potato.
Infections
M. paratuberculosis Heat Shock Protein 65 and Human Diseases: Bridging Infection and Autoimmunity.
Infections
Mapping of a visceral leishmaniasis-specific immunodominant B-cell epitope of Leishmania donovani Hsp70.
Infections
mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.
Infections
Mechanisms of HSP65 expression induced by gamma delta T cells in murine Toxoplasma gondii infection.
Infections
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells.
Infections
miR-382-5p promotes porcine reproductive and respiratory syndrome virus (PRRSV) replication by negatively regulating the induction of type I interferon.
Infections
Mitochondrial distribution and function in herpes simplex virus-infected cells.
Infections
Mitochondrial Heat Shock Response Induced by Ectromelia Virus is Accompanied by Reduced Apoptotic Potential in Murine L929 Fibroblasts.
Infections
Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum.
Infections
Modulated heat shock protein expression during pathogenic Vibrio alginolyticus stress of sea bream.
Infections
Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein.
Infections
Modulation of endothelial cell damages by anti-Hsp60 autoantibodies in systemic autoimmune diseases.
Infections
Modulation of herpes simplex virus (HSV) infection of cultured neuronal cells by nerve growth factor and antibody to HSV.
Infections
Modulation of Hsp60 in response to coral brown band disease.
Infections
Modulation of macrophage heat shock proteins (HSPs) expression in response to intracellular infection by virulent and avirulent strains of Leishmania donovani.
Infections
Modulation of stress protein (hsp27 and hsp70) expression in CD4+ lymphocytic cells following acute infection with human immunodeficiency virus type-1.
Infections
Modulation of the unfolded protein response pathway as an antiviral approach in airway epithelial cells.
Infections
Molecular and immunological characterisation of the glucose regulated protein 78 of Leishmania donovani(1).
Infections
Molecular chaperones and the immune response.
Infections
Molecular characterization and expression analysis of Hsp90 in Schizothorax prenanti.
Infections
Molecular characterization of heat shock protein 70 gene transcripts during Vibrio harveyi infection of humphead snapper, Lutjanus sanguineus.
Infections
Molecular cloning and characterization of groESL operon in Streptococcus pneumoniae.
Infections
Molecular cloning and expression analysis of five heat shock protein 70 (HSP70) family members in Lateolabrax maculatus with Vibrio harveyi infection.
Infections
Molecular cloning of Ra-sHSPI, a novel member of the HSP20 family from Rhipicephalus annulatus salivary glands.
Infections
Molecular cloning, characterization and expression analysis of heat shock protein 90 in albino northern snakehead Channa argus.
Infections
Molecular diagnosis of fatal Nocardia farcinica pneumonia in an HIV-negative patient.
Infections
Monoclonal antibodies to heat shock protein 60 induce a protective immune response against experimental Paracoccidioides lutzii.
Infections
Mortalin restricts porcine epidemic diarrhea virus entry by downregulating clathrin-mediated endocytosis.
Infections
Multiple Chlamydiaceae species in trachoma: implications for disease pathogenesis and control.
Infections
Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer's Disease Progression.
Infections
Mycobacterial 65-kilodalton heat shock protein induces tumor necrosis factor alpha and interleukin 6, reactive nitrogen intermediates, and toxoplasmastatic activity in murine peritoneal macrophages.
Infections
Mycoplasma hyopneumoniae Inhibits Porcine Beta-Defensin 2 Production by Blocking the Unfolded Protein Response To Facilitate Epithelial Adhesion and Infection.
Infections
Nest ectoparasites increase physiological stress in breeding birds: an experiment.
Infections
Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease.
Infections
NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection.
Infections
Non-Structural Protein 2B of Human Rhinovirus 16 Activates Both PERK and ATF6 Rather Than IRE1 to Trigger ER Stress.
Infections
Novel Prophylactic Vaccine Using a Prime-Boost Method and Hemagglutinating Virus of Japan-Envelope against Tuberculosis.
Infections
Novel vaccines for the treatment of chronic HBV infection based on mycobacterial heat shock protein 70.
Infections
Nuclear transport of Epstein-Barr virus DNA polymerase is dependent on the BMRF1 polymerase processivity factor and molecular chaperone Hsp90.
Infections
Nucleopolyhedroviruses (NPV) induce the expression of small heat shock protein 25.4 in Antheraea pernyi.
Infections
Oligomerization of ICP4 and rearrangement of heat shock proteins may be important for herpes simplex virus type 1 prereplicative site formation.
Infections
Oral Immunization with a Multivalent Epitope-Based Vaccine, Based on NAP, Urease, HSP60, and HpaA, Provides Therapeutic Effect on H. pylori Infection in Mongolian gerbils.
Infections
Oral Tolerance Induced by Heat Shock Protein 65-Producing Lactococcus lactis Mitigates Inflammation in Leishmania braziliensis Infection.
Infections
Over-expression of Saccharomyces cerevisiae hsp90 enhances the virulence of this yeast in mice.
Infections
Overexpression of PLK3 Mediates the Degradation of Abnormal Prion Proteins Dependent on Chaperone-Mediated Autophagy.
Infections
Passive immunization with a monoclonal IgM antibody specific for Strongyloides ratti HSP60 protects mice against challenge infection.
Infections
Pathogenic infection and immune-related gene expression of Chinese sturgeon (Acipenser sinensis) challenged by Citrobacter freundii.
Infections
Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts.
Infections
Performance of multiplex serology in discriminating active vs past Helicobacter pylori infection in a primarily African American population in the southeastern United States.
Infections
Peripheral blood mononuclear cell responses to heat shock proteins in patients undergoing stem cell transplantation.
Infections
Persistence of Chlamydia pneumoniae in degenerative aortic valve stenosis indicated by heat shock protein 60 homologues.
Infections
Phase I dose-escalation study of a monovalent heat shock protein 70-herpes simplex virus type 2 (HSV-2) peptide-based vaccine designed to prime or boost CD8 T-cell responses in HSV-naïve and HSV-2-infected subjects.
Infections
Phloroglucinol-Mediated Hsp70 Production in Crustaceans: Protection against Vibrio parahaemolyticus in Artemia franciscana and Macrobrachium rosenbergii.
Infections
Plasma membrane expression of heat shock protein 60 in vivo in response to infection.
Infections
Pollution-induced heat shock protein expression in the amphipod Gammarus roeseli is affected by larvae of Polymorphus minutus (Acanthocephala).
Infections
Polyclonal expansion of peripheral gamma delta T cells in human Plasmodium falciparum malaria.
Infections
Polymorphism of Immune Response Genes as a Factor for Predisposition to Development of Diseases.
Infections
Polymorphisms of heat shock protein-70 (hspa1b and hspa1l Loci) do not influence infection or outcome risk in critically ill surgical patients.
Infections
Porcine epidemic diarrhea virus infections induce autophagy in Vero cells via ROS-dependent endoplasmic reticulum stress through PERK and IRE1 pathways.
Infections
Porphyromonas gingivalis heat shock protein vaccine reduces the alveolar bone loss induced by multiple periodontopathogenic bacteria.
Infections
Porphyromonas gingivalis HSP60 peptides have distinct roles in the development of atherosclerosis.
Infections
Preparation of apoptotic tumor cells with replication-incompetent HSV augments the efficacy of dendritic cell vaccines.
Infections
Prevalence of Anaplasma and Bartonella spp. in Ticks Collected from Korean Water Deer (Hydropotes inermis argyropus).
Infections
Previously undetected Chlamydia trachomatis infection, immunity to heat shock proteins and tubal occlusion in women undergoing in-vitro fertilization.
Infections
Prior immunity to Trichinella spiralis prevents (re)occurrence of an explicit stress response in intestines but not in mesenteric lymph nodes, heart and lungs from reinfected rats.
Infections
Probing the heat shock response of Corynebacterium pseudotuberculosis: the major virulence factor, phospholipase D, is downregulated at 43 degrees C.
Infections
Production of Chlamydia pneumoniae proteins in Bacillus subtilis and their use in characterizing immune responses in the experimental infection model.
Infections
Production of stress-inducible form of heat-shock protein 70 in mouse peritoneal adherent cells after in vivo infection by Francisella tularensis.
Infections
Progress and prospects for targeting Hsp90 to treat fungal infections.
Infections
Proposing BCG Vaccination for Mycobacterium avium ss. paratuberculosis (MAP) Associated Autoimmune Diseases.
Infections
Protein folding studies in vivo with a bacteriophage T4 expression-packaging-processing vector that delivers encapsidated fusion proteins into bacteria.
Infections
Proteomic analysis of differentially expressed proteins in Fenneropenaeus chinensis hemocytes upon white spot syndrome virus infection.
Infections
Pulmonary necrosis resulting from DNA vaccination against tuberculosis.
Infections
Quantitative proteomic analyses of human cytomegalovirus-induced restructuring of endoplasmic reticulum-mitochondrial contacts at late times of infection.
Infections
Quantitative proteomics analysis provides insight into the biological role of Hsp90 in BmNPV infection in Bombyx mori.
Infections
Quantitative whole-cell proteome analysis of pseudorabies virus-infected cells.
Infections
Rabies viruses leader RNA interacts with host Hsc70 and inhibits virus replication.
Infections
Real-time quantitative polymerase chain reaction (QPCR) to identify Myxobolus cerebralis in rainbow trout Oncorhynchus mykiss.
Infections
Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.
Infections
Recombinant heat shock protein 78 enhances enterovirus 71 propagation in Vero cells and is induced in SK-N-SH cells during the infection.
Infections
Recombinant protein and DNA vaccines derived from hsp60 Trichophyton mentagrophytes control the clinical course of trichophytosis in bovine species and guinea-pigs.
Infections
Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress.
Infections
Reduced levels of gamma-interferon secretion in response to chlamydial 60 kDa heat shock protein amongst women with pelvic inflammatory disease and a history of repeated Chlamydia trachomatis infections.
Infections
Regulation of an adaptor protein STING by Hsp90? to enhance innate immune responses against microbial infections.
Infections
Regulation of iNOS-Derived ROS Generation by HSP90 and Cav-1 in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine Lung Injury.
Infections
Regulation of Molecular Chaperone GRP78 by Hepatitis B Virus: Control of Viral Replication and Cell Survival.
Infections
Regulation of Toll-like receptor 2 interaction with Ecgp96 controls Escherichia coli K1 invasion of brain endothelial cells.
Infections
Regulation of Viral Replication, Apoptosis and Pro-Inflammatory Responses by 17-AAG during Chikungunya Virus Infection in Macrophages.
Infections
Relationship between Helicobacter pylori, gastric parietal cell antibodies and heat shock proteins.
Infections
Relative increase in IgG antibodies to Pseudomonas aeruginosa 60-kDa GroEL in prediabetic patients with cystic fibrosis.
Infections
Remodeling of the Histoplasma Capsulatum Membrane Induced by Monoclonal Antibodies.
Infections
Reprogramming the unfolded protein response for replication by porcine reproductive and respiratory syndrome virus.
Infections
Reversal of Schistosome Resistance In Biomphalaria glabrata By Heat Shock May Be Dependent On Snail Genotype.
Infections
Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae.
Infections
Role of Heat-Shock Protein (HSP) 70-2 Genotype in Peptic Ulcer in Japanese Population.
Infections
Role of immune responses to a GroEL heat shock protein in preventing brucellosis in mice vaccinated with Brucella abortus strain RB51.
Infections
Role of innate immune cells in protection against Toxoplasma gondii at inflamed site.
Infections
Roles of NKT cells in resistance against infection with Toxoplasma gondii and in expression of heat shock protein 65 in the host macrophages.
Infections
Roles of Toxoplasma gondii-derived heat shock protein 70 in host defense against T. gondii infection.
Infections
Selection of maize inbred lines and gene expression for resistance to ear rot.
Infections
Selective induction of chromosomal gene expression by human cytomegalovirus.
Infections
Semi-nested PCR detection of Bartonella henselae in Ixodes persulcatus ticks from Western Siberia, Russia.
Infections
Sendai virus pneumonia: evidence for the early recruitment of gamma delta T cells during the disease course.
Infections
Serological association between Chlamydia pneumoniae infection and age-related macular degeneration.
Infections
Serological Testing for Mycobacterial Heat Shock Protein Hsp65 Antibody in Health and Diseases.
Infections
Serum antibody response to the heat shock protein 60 of Chlamydia trachomatis in women with developing cervical cancer.
Infections
Serum biomarkers differentiating Kawasaki disease from febrile infections: A pilot case-control study.
Infections
Serum immunoglobulin G antibodies to chlamydial heat shock protein 60 but not to human and bacterial homologs are associated with coronary artery disease.
Infections
SGTA-dependent regulation of Hsc70 promotes cytosol entry of SV40 from the ER.
Infections
Shock response induced in rat brain and spleen during primary infection with Trichinella spiralis larvae.
Infections
Single dose of a vaccine based on DNA encoding mycobacterial hsp65 protein plus TDM-loaded PLGA microspheres protects mice against a virulent strain of Mycobacterium tuberculosis.
Infections
Small heat-shock proteins: important players in regulating cellular proteostasis.
Infections
Small molecular compounds that inhibit hepatitis C virus replication through destabilizing heat shock cognate 70 messenger RNA.
Infections
Spatial and Temporal Resolution of Global Protein Synthesis during HSV Infection Using Bioorthogonal Precursors and Click Chemistry.
Infections
Streptococcus pneumoniae heat shock protein 70 does not induce human antibody responses during infection.
Infections
Structure and regulation of the HSP90 gene from the pathogenic fungus Candida albicans.
Infections
Study on the cloning, expression and the immunogenicity of helicobacter pylori heat shock protein 60 gene.
Infections
Study on the immune response to recombinant Hsp70 protein from Megalobrama amblycephala.
Infections
Subcellular localization of the 65-kDa heat shock protein in mycobacteria by immunoblotting and immunogold ultracytochemistry.
Infections
Subcellular Location of Piscirickettsia salmonis Heat Shock Protein 60 (Hsp60) Chaperone by Using Immunogold Labeling and Proteomic Analysis.
Infections
Surface localized Heat Shock Protein 20 (HslV) of Helicobacter pylori.
Infections
Surface-associated Hsp60 chaperonin of Leptospira interrogans serovar Autumnalis N2 strain as an immunoreactive protein.
Infections
Survey of molecular chaperone requirement for the biosynthesis of hamster polyomavirus VP1 protein in Saccharomyces cerevisiae.
Infections
Susceptibility of heat shock protein 70.1-deficient C57BL/6 J, wild-type C57BL/6 J and A/J mice to Trypanosoma congolense infection.
Infections
Susceptibility of human monocyte-macrophages to Chlamydia pneumoniae infection in vitro is highly variable and associated with levels of soluble CD14 and C. pneumoniae IgA and human HSP-IgG antibodies in serum.
Infections
Systemic and mucosal immunization with Candida albicans hsp90 elicits hsp90-specific humoral response in vaginal mucosa which is further enhanced during experimental vaginal candidiasis.
Infections
T-cell recognition of mycobacterial GroES peptides in Thai leprosy patients and contacts.
Infections
T-cell, antibody, and cytokine responses to homologs of the 60-kilodalton heat shock protein in Helicobacter pylori infection.
Infections
Tandem Mass Tag-Based Quantitative Proteomic Analysis of Chicken Bursa of Fabricius Infected With Reticuloendotheliosis Virus.
Infections
Targeted induction of antigen expression within dendritic cells modulates antigen-specific immunity afforded by recombinant BCG.
Infections
Targeting the Kingella Kingae groEL Gene is a Reliable Method for the Molecular Diagnosis of K. Kingae Infection and Carriage.
Infections
The 72K IE1 and 80K IE2 proteins of human cytomegalovirus independently trans-activate the c-fos, c-myc and hsp70 promoters via basal promoter elements.
Infections
The adverse events of haematopoietic stem cell transplantation are associated with gene polymorphism within human leukocyte antigen region.
Infections
The Cellular Chaperone Heat Shock Protein 90 Is Required for Foot-and-Mouth Disease Virus Capsid Precursor Processing and Assembly of Capsid Pentamers.
Infections
The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity.
Infections
The cellular stress response of the scleractinian coral Goniopora columna during the progression of the black band disease.
Infections
The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection.
Infections
The characteristics of the expression of heat shock proteins and COX-2 in the liver of hamsters infected with Clonorchis sinensis, and the change of endocrine hormones and cytokines.
Infections
The clonal antibody response to Pseudomonas aeruginosa heat shock protein is highly diverse in cystic fibrosis patients.
Infections
The co-chaperone Cdc37 regulates the rabies virus phosphoprotein stability by targeting to Hsp90AA1 machinery.
Infections
The curli biogenesis genes expression level is unassociated with Enterobacter cloacae hsp60 clusters and PFGE genotypes.
Infections
The dynamics of heat shock system activation in Monomac-6 cells upon Helicobacter pylori infection.
Infections
The E1A 13S product of adenovirus 5 activates transcription of the cellular human HSP70 gene.
Infections
The endosymbiotic bacterium Holospora obtusa enhances heat-shock gene expression of the host Paramecium caudatum.
Infections
The Escherichia coli chaperonin 60 (groEL) is a potent stimulator of osteoclast formation.
Infections
The Heat Shock Protein 70 Family of Chaperones Regulates All Phases of the Enterovirus A71 Life Cycle.
Infections
The heat shock protein 90 of Eimeria tenella is essential for invasion of host cell and schizont growth.
Infections
The Heat-Induced Molecular Disaggregase Hsp104 of Candida albicans Plays a Role in Biofilm Formation and Pathogenicity in a Worm Infection Model.
Infections
The Herpes Simplex Virus 1 Immediate Early Protein ICP22 Is a Functional Mimic of a Cellular J Protein.
Infections
The hsc70 gene which is slightly induced by heat is the main virus inducible member of the hsp70 gene family.
Infections
The Hsp90 inhibitor 17-DMAG decreases infection of porcine circovirus type 2 in mice.
Infections
The Hsp90 of Candida albicans can confer Hsp90 functions in Saccharomyces cerevisiae: a potential model for the processes that generate immunogenic fragments of this molecular chaperone in C. albicans infections.
Infections
The induction of stromule formation by a plant DNA-virus in epidermal leaf tissues suggests a novel intra- and intercellular macromolecular trafficking route.
Infections
The interaction of white spot syndrome virus envelope protein VP28 with shrimp Hsc70 is specific and ATP-dependent.
Infections
The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression.
Infections
The mechanism of heat-shock protein 70 gene expression abolition in gastric epithelium caused by Helicobacter pylori infection.
Infections
The Molecular Mechanism of Hemocyte Immune Response in Marsupenaeus japonicus Infected With Decapod Iridescent Virus 1.
Infections
The multi-drug efflux system AcrABZ-TolC is essential for infection of Salmonella Typhimurium by the flagellum-dependent bacteriophage Chi.
Infections
The mycobacterial GroEL stress protein: a common target of T-cell recognition in infection and autoimmunity.
Infections
The N terminus of the head protein of T4 bacteriophage directs proteins to the GroEL chaperonin.
Infections
The Noncanonical Heat Shock Protein PvNod22 Is Essential for Infection Thread Progression During Rhizobial Endosymbiosis in Common Bean.
Infections
The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle.
Infections
The outcome of poliovirus infections in K562 cells is cytolytic rather than persistent after hemin-induced differentiation.
Infections
The Peptide-Binding and ATPase Domains of Recombinant hsc70 Are Required To Interact with Rotavirus and Reduce Its Infectivity.
Infections
The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice.
Infections
The promoter polymorphism of the IL-6 gene is associated with levels of antibodies to 60-kDa heat-shock proteins.
Infections
The Pseudomonas aeruginosa HSP90-like protein HtpG regulates IL-8 expression through NF-?B/p38 MAPK and CYLD signaling triggered by TLR4 and CD91.
Infections
The role of heat shock protein 70 in resistance to Salmonella enteritidis in broiler chickens subjected to neonatal feed restriction and thermal stress.
Infections
The role of Heat Shock Protein 90 (HSP90) in Hepatitis E Virus (HEV) Capsid Trafficking.
Infections
The role of heat shock proteins in atherosclerosis.
Infections
The Role of Heat Shock Proteins in Leukemia.
Infections
The role of hsp90 in fungal infection.
Infections
The Role of Prostate Apoptosis Response-4 (Par-4) in Mycobacterium tuberculosis Infected Macrophages.
Infections
The role of the infectious agents in the pathogenesis and evolution of atherosclerosis.
Infections
Theiler's murine encephalomyelitis virus infection induces a redistribution of heat shock proteins 70 and 90 in BHK-21 cells, and is inhibited by novobiocin and geldanamycin.
Infections
Tick-borne encephalitis virus triggers inositol-requiring enzyme 1 (IRE1) and transcription factor 6 (ATF6) pathways of unfolded protein response.
Infections
Time-Resolved Proteome Analysis of Listeria monocytogenes during Infection Reveals the Role of the AAA+ Chaperone ClpC for Host Cell Adaptation.
Infections
Tobamovirus infection is independent of HSP101 mRNA induction and protein expression.
Infections
Tolerization against atherosclerosis using heat shock protein 60.
Infections
Toll-like receptor 4-mediated respiratory syncytial virus disease and lung transcriptomics in differentially susceptible inbred mouse strains.
Infections
Tomato plant cell death induced by inhibition of HSP90 is alleviated by Tomato yellow leaf curl virus infection.
Infections
Transcriptional analysis of Rickettsia prowazekii invasion gene homolog (invA) during host cell infection.
Infections
Transcriptome Analysis Reveals Unfolded Protein Response Was Induced During the Early Stage of Burkholderia pseudomallei Infection in A549 Cells.
Infections
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Infections
TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity.
Infections
Ts-Hsp70 induces protective immunity against Trichinella spiralis infection in mouse by activating dendritic cells through TLR2 and TLR4.
Infections
Two putative protein export regulators promote malaria blood stage development in vivo.
Infections
Two routes of infection with Photobacterium damselae subsp. piscicida are effective in the modulation of the transcription of immune related genes in Solea senegalensis.
Infections
Tyrosine phosphorylation modulates mitochondrial chaperonin Hsp60 and delays rotavirus NSP4-mediated apoptotic signaling in host cells.
Infections
Unsuspected Chlamydia trachomatis infection and in vitro fertilization outcome.
Infections
Up-regulation of Hsp60 in response to skeleton eroding band disease but not by algal overgrowth in the scleractinian coral Acropora muricata.
Infections
Urine heat shock protein 70 levels as a marker of urinary tract infection in children.
Infections
Use of immunological methods to the detection of toxoplasmosis and heat shock protein HSP70 in men.
Infections
Vaccinia virus infection induces a stress response that leads to association of Hsp70 with viral proteins.
Infections
VceC Mediated IRE1 Pathway and Inhibited CHOP-induced Apoptosis to Support Brucella Replication in Goat Trophoblast Cells.
Infections
VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition.
Infections
Virulence factor RNA transcript expression in the Leishmania Viannia subgenus: influence of species, isolate source, and Leishmania RNA virus-1.
Infections
Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection.
Infections
Voltage dependent anion channel is redistributed during Japanese encephalitis virus infection of insect cells.
Infections
VP1-binding protein glucose-regulated protein 78 as an important mediator for enterovirus 71 infecting human brain microvascular endothelial cells.
Infections
VP1-Binding Protein Glucose-regulated protein 78 as an important mediator for Enterovirus 71 infecting Human Brain Microvascular Endothelial Cells.
Infections
Whole-genome sequencing provides new insights into genetic mechanisms of tropical adaptation in Nellore (Bos primigenius indicus).
Infections
[ANTI-Hsp60 ANTIBODIES IN ARTERIAL HYPERTENTION DIFERENT DEGREE OF SEVERITY].
Infections
[Behaviour of gamma delta TCR+ T cells during the course of nontuberculous mycobacterial infections and proliferative response of host lymphocytes to 65kD heat shock protein]
Infections
[Chlamydia pneumoniae and cytomegalovirus in degenerative aortic valve stenoses]
Infections
[Chlamydial heat shock protein (hsp 60) and fertility disorders]
Infections
[Detection of serum heat shock protein 70 level in patients with hepatitis C infection and its role in cytotoxicity of CTLs induced by HSP70-HCV peptide complex]
Infections
[Effect of heat shock protein 70 on nuclear factor-KappaB/inhibitor protein-alpha of nuclear factor-KappaB in brain edema induced by infection in rat]
Infections
[Effect of total flavonoids of astragalus on endoplasmic reticulum chaperone, calumenin and connecxin 43 in suckling mouse myocardium with myocarditis caused by coxsackievirus B3].
Infections
[Evidence of antibodies against the chlamydial heat shock protein (cHSP60) in women from "in vitro" fertilization program]
Infections
[Examination of possible role of the chlamydial stress proteins in pathogenesis of ectopic pregnancy].
Infections
[Possible roles of infections and heat shock proteins in rheumatoid arthritis]
Infections
[Protective effects of co-immunization with SjCTPI-Hsp70 and interleukin-12 DNA vaccines against Schistosoma japonicum challenge infection in water buffalo]
Infections
[Rapid detection and identification of mycobacteria by the PCR assay based on the co-amplification of the gene IS6110 and groEL]
Infections
[Relationship between Pi-Wei damp-heat syndrome with expressions of nuclear factor-kappaBmRNA and heat shock protein 70 mRNA in patients with chronic gastritis]
Infections
[Role of chronic infection and heat shock proteins in peripheral arterial disease]
Infections
[Roles of transforming growth factor - ?1 and heat shock protein 47 in progression of Schistosoma japonicum-induced hepatic fibrosis].
Infections
[Significance of heat shock protein 70 in cerebrospinal fluid in differential diagnosis of central nervous system infection in children]
Infections
[The effect of astragalus injection on the expression of endoplasmic reticulum stress chaperonin GRP78 and GRP94 mRNA in adriamycin-injured cardiomyocytes with calumenin silencing by shRNA].
Infections
[The relationship between miRNA378, calumenin and endoplasmic reticulum stress in suckling mouse myocardium with myocarditis caused by adriamycin].
Infections
[Thoughts on pathogenesis of Helicobacter pylori related gastrosis with splenogastric hygropyrexia syndrome]
Infections
[Validity of the Morawietz classification for evaluation of periprosthetic tissue].
Infertility
A block in the road to fertility: autoantibodies to heat-shock protein 90-beta in human ovarian autoimmunity.
Infertility
A PROSPECTIVE STUDY TO ANALYZE THE SPECIFICITY OF CHLAMYDIAL HEAT SHOCK PROTEIN (CHSP60) ANTIBODIES TO DIAGNOSE TUBAL INFERTILITY.
Infertility
Antibodies to Chlamydia trachomatis heat shock proteins Hsp60 and Hsp10 and subfertility in general population at age 31.
Infertility
Antibodies to the chlamydial 60 kilodalton heat shock protein in women with tubal factor infertility.
Infertility
Association of uterine and salpingeal fibrosis with chlamydial hsp60 and hsp10 antigen-specific antibodies in Chlamydia-infected koalas.
Infertility
Cell-mediated immunity to human and Escherichia coli 60-kDa heat shock protein in women: association with a history of spontaneous abortion and endometriosis.
Infertility
Chlamydia infection and subfertility.
Infertility
Chlamydia trachomatis and chlamydial heat shock protein 60-specific antibody and cell-mediated responses predict tubal factor infertility.
Infertility
Chlamydia trachomatis heat shock protein-60 induced interferon-gamma and interleukin-10 production in infertile women.
Infertility
Chlamydia trachomatis Infection, Immunity, and Pregnancy Outcome.
Infertility
Circulating antibodies to a conserved epitope of the Chlamydia trachomatis 60 kDa heat shock protein (hsp60) in infertile couples and its relationship to antibodies to C.trachomatis surface antigens and the Escherichia coli and human HSP60.
Infertility
Combining individual Chlamydia trachomatis IgG antibodies MOMP, TARP, CPAF, OMP2, and HSP60 for tubal factor infertility prediction.
Infertility
Effects of KH-204 on the expression of heat shock protein 70 and germ cell apoptosis in infertility rat models.
Infertility
Expression of heat shock protein 70 kDa in human endometrium of normal and infertile women.
Infertility
Expression of the 60 kDa heat shock protein in peritoneal fluids from women with endometriosis: implications for endometriosis-associated infertility.
Infertility
Genome-wide dissection of AP2/ERF and HSP90 gene families in five legumes and expression profiles in chickpea and pigeonpea.
Infertility
Hsp60 expression and localization in different tissues and testis development of male cattle (cattle-yak and yak).
Infertility
Humoral immune response to the chlamydial heat shock proteins hsp60 and hsp70 in Chlamydia-associated chronic salpingitis with tubal occlusion.
Infertility
Immune Recognition of the 60kD Heat Shock Protein: Implications for Subsequent Fertility.
Infertility
Immunopathogenesis of chlamydia trachomatis infections in women.
Infertility
Induction of infertility by the Chlamydia trachomatis mouse pneumonitis biovar in strains of mice that differ in their response to the 60 kDa heat shock protein.
Infertility
Infertility following pelvic inflammatory disease.
Infertility
Levels of oestrogen receptor, progesterone receptor and ?B-crystallin in eutopic endometrium in relation to pregnancy in women with endometriosis.
Infertility
Male immunity to the chlamydial 60 kDa heat shock protein (HSP 60) - associated with semen quality?
Infertility
Members of the 70 kDa heat shock protein family specifically recognize sulfoglycolipids: role in gamete recognition and mycoplasma-related infertility.
Infertility
Microbiota-based analysis reveals specific bacterial traits and a novel strategy for the diagnosis of infectious infertility.
Infertility
Mycobacterial heat shock protein 65 mediated metabolic shift in decidualization of human endometrial stromal cells.
Infertility
Persistent Chlamydia trachomatis infections resist apoptotic stimuli.
Infertility
Reduced levels of gamma-interferon secretion in response to chlamydial 60 kDa heat shock protein amongst women with pelvic inflammatory disease and a history of repeated Chlamydia trachomatis infections.
Infertility
Regulation by Hsp27/P53 in testis development and sperm apoptosis of male cattle (cattle-yak and yak).
Infertility
Roles of Grp78 in Female Mammalian Reproduction.
Infertility
Serologic responses of infertile women to the 60-kd chlamydial heat shock protein (hsp60).
Infertility
Seroreactivity to Chlamydia trachomatis Hsp10 correlates with severity of human genital tract disease.
Infertility
Single nucleotide polymorphisms of the heat shock protein 90 gene in varicocele-associated infertility.
Infertility
Sub-fertility in crossbred bulls: Identification of proteomic alterations in spermatogenic cells using high throughput comparative proteomics approach.
Infertility
The presence of serum antibody to the chlamydial heat shock protein (CHSP60) as a diagnostic test for tubal factor infertility.
Infertility
The Unmysterious Roles of HSP90: Ovarian Pathology and Autoantibodies.
Infertility
Tubal factor infertility is associated with antibodies against Chlamydia trachomatis heat shock protein 60 (HSP60) but not human HSP60.
Infertility
[Serologic diagnosis of chlamydial and Mycoplasma pneumoniae infections]
Infertility, Female
Immune-mediated destruction of ovarian follicles associated with the presence of HSP90 antibodies.
Infertility, Male
A mutation in Thermosensitive Male Sterile 1, encoding a heat shock protein with DnaJ and PDI domains, leads to thermosensitive gametophytic male sterility in Arabidopsis.
Infertility, Male
Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis.
Infertility, Male
Decreased expression of the heat shock protein hsp70-2 is associated with the pathogenesis of male infertility.
Infertility, Male
Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo.
Infertility, Male
Genetic analysis of viable Hsp90 alleles reveals a critical role in Drosophila spermatogenesis.
Infertility, Male
HSPA1L and HSPA1B gene polymorphisms and haplotypes are associated with idiopathic male infertility in Iranian population.
Infertility, Male
Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertility.
Infertility, Male
Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility.
Infertility, Male
The association of rs11457523 in HSP90AA1 with idiopathic male infertility in the Chinese population.
Infertility, Male
The role of heat shock protein 70 (Hsp 70) in male infertility: is it a line of defense against sperm DNA fragmentation?
Inflammatory Bowel Diseases
Autoantibodies to human stress proteins. A survey of various rheumatic and other inflammatory diseases.
Inflammatory Bowel Diseases
Cellular and humoral immunity to the 60-kD heat shock protein in inflammatory bowel disease.
Inflammatory Bowel Diseases
De novo and rare mutations in the HSPA1L heat shock gene associated with inflammatory bowel disease.
Inflammatory Bowel Diseases
Enhanced intestinal expression of heat shock protein 70 in patients with inflammatory bowel diseases.
Inflammatory Bowel Diseases
Evaluation of ubiquitinated proteins by proteomics reveals the role of the ubiquitin proteasome system in the regulation of Grp75 and Grp78 chaperone proteins during intestinal inflammation.
Inflammatory Bowel Diseases
Heat shock protein 47 can be a new target molecule for intestinal fibrosis related to inflammatory bowel disease.
Inflammatory Bowel Diseases
How autophagy controls the intestinal epithelial barrier.
Inflammatory Bowel Diseases
Hsp60 and Hsp10 increase in colon mucosa of Crohn's disease and ulcerative colitis.
Inflammatory Bowel Diseases
Impaired humoral immune response against mycobacterial 65-kDa heat shock protein (HSP65) in patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
Intestinal expression of human heat shock protein 90 in patients with Crohn's disease and ulcerative colitis.
Inflammatory Bowel Diseases
Involvement of heat shock protein a4/apg-2 in refractory inflammatory bowel disease.
Inflammatory Bowel Diseases
Mucosal expression by B7-positive cells of the 60-kilodalton heat-shock protein in inflammatory bowel disease.
Inflammatory Bowel Diseases
Oral targeted delivery by nanoparticles enhances efficacy of an Hsp90 inhibitor by reducing systemic exposure in murine models of colitis and colitis-associated cancer.
Inflammatory Bowel Diseases
Peripheral blood mononuclear cell proliferative responses to soluble and particulate heat shock protein 65 in health and inflammatory bowel disease.
Inflammatory Bowel Diseases
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Inflammatory Bowel Diseases
Targeted Inhibition of Heat Shock Protein 90 Suppresses Tumor Necrosis Factor-? and Ameliorates Murine Intestinal Inflammation.
Inflammatory Bowel Diseases
[Induction of mucosal immunity to mycobacterial heat shock protein (hsp) 65 by colonic inoculation of plasmid DNA encoding hsp65]
Influenza in Birds
Identification of Hsp90 as a species independent H5N1 avian influenza A virus PB2 interacting protein.
Influenza in Birds
[Complex of recombinant heat shock protein with lipopolysaccharide induces rapid protection of mice against Salmonella typhimurium and avirulent for humans avian influenza virus H5N2]
Influenza, Human
A truncated C-terminal fragment of Mycobacterium tuberculosis HSP70 enhances cell-mediated immune response and longevity of the total IgG to influenza A virus M2e protein in mice.
Influenza, Human
Anti-influenza virus activity of benzo[d]thiazoles that target heat shock protein 90.
Influenza, Human
AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.
Influenza, Human
Autophagy is involved in regulating influenza A virus RNA and protein synthesis associated with both modulation of Hsp90 induction and mTOR/p70S6K signaling pathway.
Influenza, Human
Broadly Protective CD8+ T Cell Immunity to Highly Conserved Epitopes Elicited by Heat Shock Protein gp96-Adjuvanted Influenza Monovalent Split Vaccine.
Influenza, Human
Construction of recombinant fusion protein of influenza, a virus neuraminidase and heat shock protein 70 gene: expression in baculovirus and bioactivity.
Influenza, Human
Epitope tagging of the human endoplasmic reticulum HSP70 protein, BiP, to facilitate analysis of BiP--substrate interactions.
Influenza, Human
Functional role of Hsp60 as a positive regulator of human viral infection progression.
Influenza, Human
Harnessing an RNA-mediated chaperone for the assembly of influenza hemagglutinin in an immunologically relevant conformation.
Influenza, Human
Heat shock protein 70 inhibits the activity of influenza a virus ribonucleoprotein and blocks the replication of virus in vitro and in vivo.
Influenza, Human
Heat shock protein 70 is related to thermal inhibition of nuclear export of the influenza virus ribonucleoprotein complex.
Influenza, Human
Heat shock protein 70 modulates influenza a virus polymerase activity.
Influenza, Human
Heat shock protein gp96 adjuvant induces T cell responses and cross-protection to a split influenza vaccine.
Influenza, Human
Hsc70 regulates the nuclear export but not the import of influenza viral RNP: A possible target for the development of anti-influenza virus drugs.
Influenza, Human
Hsp90 inhibitors reduce influenza virus replication in cell culture.
Influenza, Human
Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins.
Influenza, Human
Identification of Hsc70 as an influenza virus matrix protein (M1) binding factor involved in the virus life cycle.
Influenza, Human
Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis.
Influenza, Human
Identification of immunoglobulin heavy chain binding protein as glucose-regulated protein 78 on the basis of amino acid sequence, immunological cross-reactivity, and functional activity.
Influenza, Human
Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway.
Influenza, Human
Influenza A Virus Induces Autophagy by Its Hemagglutinin Binding to Cell Surface Heat Shock Protein 90AA1.
Influenza, Human
Influenza A virus neuraminidase protein interacts with Hsp90, to stabilize itself and enhance cell survival.
Influenza, Human
Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.
Influenza, Human
Influenza virus budding does not require a functional AAA+ ATPase, VPS4.
Influenza, Human
Influenza Virus Infection Induces the Nuclear Relocalization of the Hsp90 Co-Chaperone p23 and Inhibits the Glucocorticoid Receptor Response.
Influenza, Human
Influenza virus inhibits cleavage of the HSP70 pre-mRNAs at the polyadenylation site.
Influenza, Human
Interaction of Hsp40 with influenza virus M2 protein: implications for PKR signaling pathway.
Influenza, Human
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits.
Influenza, Human
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: role of Hsp90 acetylation.
Influenza, Human
Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2.
Influenza, Human
PBP74, a new member of the mammalian 70-kDa heat shock protein family, is a mitochondrial protein.
Influenza, Human
Protection against influenza H7N9 virus challenge with a recombinant NP-M1-HSP60 protein vaccine construct in BALB/c mice.
Influenza, Human
Responses to gram negative enteric bacterial antigens by synovial T cells from patients with juvenile chronic arthritis: recognition of heat shock protein HSP60.
Influenza, Human
Selective response of gamma delta T-cell hybridomas to orthomyxovirus-infected cells.
Influenza, Human
Subcellular localization and interactions of Infectious Salmon Anemia Virus (ISAV) M1 and NEP as well as host Hsc70.
Influenza, Human
Synthetic peptides non-covalently bound to bacterial hsp 70 elicit peptide-specific T-cell responses in vivo.
Influenza, Human
Synthetic peptides representing T-cell epitopes act as carriers in pneumococcal polysaccharide conjugate vaccines.
Influenza, Human
The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity.
Influenza, Human
The effect of C-terminal mutations of HSP60 on protein folding.
Influenza, Human
The impact of DR3 microvariation on peptide binding: the combinations of specific DR beta residues critical to binding differ for different peptides.
Influenza, Human
The NS1 protein of influenza a virus interacts with heat shock protein Hsp90 in human alveolar basal epithelial cells: implication for virus-induced apoptosis.
Insulin Resistance
Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance.
Insulin Resistance
Adipocytes from new zealand obese mice exhibit aberrant proinflammatory reactivity to the stress signal heat shock protein 60.
Insulin Resistance
Aging Does Not Reduce Heat Shock Protein 70 in the Absence of Chronic Insulin Resistance.
Insulin Resistance
AMP-activated protein kinase-mediated expression of heat shock protein beta 1 enhanced insulin sensitivity in the skeletal muscle.
Insulin Resistance
An acylic polyisoprenoid derivative, geranylgeranylacetone protects against visceral adiposity and insulin resistance in high-fat-fed mice.
Insulin Resistance
Anti-diabetic effect and mechanism of Kursi Wufarikun Ziyabit in L6 rat skeletal muscle cells.
Insulin Resistance
Association of extracellular heat shock protein 70 and insulin resistance in type 2 diabetes; independent of obesity and C-reactive protein.
Insulin Resistance
Attenuation of exercise-induced heat shock protein 72 expression blunts improvements in whole-body insulin resistance in rats with type 2 diabetes.
Insulin Resistance
Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the endoplasmic reticulum.
Insulin Resistance
Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance.
Insulin Resistance
Chaperone-Based Therapeutic Target Innovation: Heat Shock Protein 70 (HSP70) for Type 2 Diabetes Mellitus.
Insulin Resistance
Decreased expression of heat shock protein 20 in colorectal cancer and its implication in tumorigenesis.
Insulin Resistance
Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance.
Insulin Resistance
Disruption of cyclophilin D-mediated calcium transfer from the ER to mitochondria contributes to hepatic ER stress and insulin resistance.
Insulin Resistance
Effects of insulin resistance on geranylgeranylacetone-induced expression of heat shock protein 72 and cardioprotection in high-fat diet rats.
Insulin Resistance
Endoplasmic reticulum chaperone GRP78 regulates macrophage function and insulin resistance in diet-induced obesity.
Insulin Resistance
Glucose oxidase induces insulin resistance via influencing multiple targets in vitro and in vivo: The central role of oxidative stress.
Insulin Resistance
Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance.
Insulin Resistance
GRP78 overproduction in pancreatic beta cells protects against high-fat-diet-induced diabetes in mice.
Insulin Resistance
Heat Shock Protein 60 as a Mediator of Adipose Tissue Inflammation and Insulin Resistance.
Insulin Resistance
Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice.
Insulin Resistance
Heat shock proteins in obesity: links to cardiovascular disease.
Insulin Resistance
Heat shock response regulates insulin sensitivity and glucose homeostasis: pathophysiological impact and therapeutic potential.
Insulin Resistance
Heat shock treatment with mild electrical stimulation safely reduced inflammatory markers in healthy male subjects.
Insulin Resistance
Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet.
Insulin Resistance
HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue.
Insulin Resistance
Hsp70 plays an important role in high-fat diet induced gestational hyperglycemia in mice.
Insulin Resistance
HSP70-hom gene polymorphisms modify the association of diethylhexyl phthalates with insulin resistance.
Insulin Resistance
HSP72 protects against obesity-induced insulin resistance.
Insulin Resistance
Hsp90? knockdown in DIO mice reverses insulin resistance and improves glucose tolerance.
Insulin Resistance
Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity.
Insulin Resistance
Hypertrophic Adipocyte-Derived Exosomal miR-802-5p Contributes to Insulin Resistance in Cardiac Myocytes Through Targeting HSP60.
Insulin Resistance
Impaired Oxidative Metabolism and Inflammation are Associated with Insulin Resistance in ER{alpha} Deficient Mice.
Insulin Resistance
Improvement of insulin sensitivity by a novel drug candidate, BGP-15, in different animal studies.
Insulin Resistance
Inducing Muscle Heat Shock Protein 70 Improves Insulin Sensitivity and Muscular Performance in Aged Mice.
Insulin Resistance
Induction chemotherapy reduces extracellular heat shock protein 72 levels, inflammation, lipoperoxidation and changes insulin sensitivity in children and adolescents newly diagnosed with acute lymphoblastic leukemia.
Insulin Resistance
Induction of heat shock proteins may combat insulin resistance.
Insulin Resistance
Inhibition of matrix metalloproteinase-2 improves endothelial function and prevents hypertension in insulin resistant rats.
Insulin Resistance
Insulin resistance contributes to multidrug resistance in HepG2 cells via activation of the PERK signaling pathway and upregulation of Bcl-2 and P-gp.
Insulin Resistance
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism.
Insulin Resistance
Involvement of endoplasmic reticulum stress in insulin resistance and diabetes.
Insulin Resistance
Jiangtang Xiaoke granule attenuates glucose metabolism disorder via regulating endoplasmic reticulum stress in the liver of type 2 diabetes mellitus mice.
Insulin Resistance
Leptin regulation of Hsp60 impacts hypothalamic insulin signaling.
Insulin Resistance
Methylglyoxal attenuates insulin signaling and downregulates the enzymes involved in cholesterol biosynthesis.
Insulin Resistance
Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials.
Insulin Resistance
Mitochondrial stress protein HSP60 regulates ER stress-induced hepatic lipogenesis.
Insulin Resistance
Muscle Heat Shock Protein 70 Predicts Insulin Resistance With Aging.
Insulin Resistance
Oral supplementations with L-glutamine or L-alanyl-L-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance.
Insulin Resistance
Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice.
Insulin Resistance
Passive exposure to heat improves glucose metabolism in overweight humans.
Insulin Resistance
Plasma HSP70 Levels Correlate with Health Risk Factors and Insulin Resistance in African American Subjects.
Insulin Resistance
Reduced nuclear protein 1 expression improves insulin sensitivity and protects against diet-induced glucose intolerance through up-regulation of heat shock protein 70.
Insulin Resistance
Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance.
Insulin Resistance
Serum heat shock protein 27 antigen and antibody levels appear to be related to the macrovascular complications associated with insulin resistance: a pilot study.
Insulin Resistance
Skeletal muscle-specific overexpression of heat shock protein 72 improves skeletal muscle insulin-stimulated glucose uptake but does not alter whole body metabolism.
Insulin Resistance
Strength training improves insulin resistance and differently affects mitochondria in skeletal muscle and visceral adipose tissue in high-fat fed mice.
Insulin Resistance
The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.
Insulin Resistance
The relationship between heat shock protein 72 expression in skeletal muscle and insulin sensitivity is dependent on adiposity.
Insulin Resistance
TIMING OF ACUTE PASSIVE HEATING ON GLUCOSE TOLERANCE AND BLOOD PRESSURE IN PEOPLE WITH TYPE 2 DIABETES: A RANDOMIZED, BALANCED CROSSOVER, CONTROL TRIAL.
Insulin Resistance
Tissue-specific regulation and expression of heat shock proteins in type 2 diabetic monkeys.
Insulin Resistance
Transthyretin contributes to insulin resistance and diminishes exercise-induced insulin sensitivity in obese mice by inhibiting AMPK activity in skeletal muscle.
Insulin Resistance
[Effect and Mechanism of Litchi Semen Effective Constituents on Insulin Resistance in Rats with Type 2 Diabetes Mellitus].
Insulin Resistance
[The role of hsp60 and hsp70 kDa heat shock protein families in different types of diabetes mellitus]
Insulinoma
Attenuation of unfolded protein response and apoptosis by mReg2 induced GRP78 in mouse insulinoma cells.
Insulinoma
Endoplasmic reticulum redox state is not perturbed by pharmacological or pathological endoplasmic reticulum stress in live pancreatic ?-cells.
Insulinoma
Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes.
Insulinoma
Identification and characterization of interactions between abscisic acid and human heat shock protein 70 family members.
Insulinoma
Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.
Insulinoma
NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells.
Insulinoma
Proteome of the insulin-secreting Min6 cell porosome complex: involvement of Hsp90 in its assembly and function.
Insulinoma
The immunosuppressive and protective ability of glucose-regulated protein 78 for improvement of alloimmunity in beta cell transplantation.
Intellectual Disability
Truncating biallelic variant in DNAJA1, encoding the co-chaperone Hsp40, is associated with intellectual disability and seizures.
Intervertebral Disc Degeneration
A comparative study of localization of heat shock protein 27 and heat shock protein 72 in the developmental and degenerative intervertebral discs.
Intervertebral Disc Degeneration
Expression of HSPA8 in Nucleus Pulposus of Lumbar Intervertebral Disc and Its Effect on Degree of Degeneration.
Intestinal Failure
Radicicol, an Hsp90 inhibitor, inhibits intestinal inflammation and leakage in abdominal sepsis.
Intestinal Fistula
Polymorphism of heat shock protein 70-2 and enterocutaneous fistula in Chinese population.
Intestinal Neoplasms
Heterozygosity of chaperone Grp78 reduces intestinal stem cell regeneration potential and protects against adenoma formation.
Intestinal Volvulus
Characterization of an hsp70 gene from the human filarial parasite, Brugia malayi (Nematoda).
Intestinal Volvulus
Onchocerca volvulus heat shock protein 70 is a major immunogen in amicrofilaremic individuals from a filariasis-endemic area.
Intestinal Volvulus
The mitochondrial heat shock protein 60 (HSP60) is up-regulated in Onchocerca volvulus after the depletion of Wolbachia.
Intracranial Hemorrhages
Neuron-Specific Enolase, S100 Calcium-Binding Protein B, and Heat Shock Protein 70 Levels in Patients With Intracranial Hemorrhage.
Intracranial Hemorrhages
The 70 kDa heat shock protein protects against experimental traumatic brain injury.
Invasive Fungal Infections
COVID19 associated mucormycosis: Is GRP78 a possible link?
Invasive Fungal Infections
Design and synthesis of fungal-selective resorcylate aminopyrazole Hsp90 inhibitors.
Iridocyclitis
Heat shock protein peptides reactive in patients with Behçet's disease are uveitogenic in Lewis rats.
Iron Deficiencies
Enhanced hydrogen peroxide sensitivity and altered stress protein expression in iron-starved Mycobacterium smegmatis.
Irritable Bowel Syndrome
Heat Shock Protein 27 Regulates the Inflammatory Response of Intestinal Epithelial Cells by the Nuclear Factor-?B Pathway.
Irritable Bowel Syndrome
Heat shock protein 70 protects mouse against post-infection irritable bowel syndrome via up-regulating intestinal ?? T cell's Th17 response.
Irritable Bowel Syndrome
Preinduced intestinal HSP70 improves visceral hypersensitivity and abnormal intestinal motility in PI-IBS mouse model.
Irritable Bowel Syndrome
Preinduction of heat shock protein 70 protects mice against post-infection irritable bowel syndrome via NF-?B and NOS/NO signaling pathways.
Ischemic Attack, Transient
Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage.
Ischemic Attack, Transient
Effects of transient cerebral ischemia on hsp40 mRNA levels in rat brain.
Ischemic Attack, Transient
Immunoelectron microscopic study of c-Fos, c-Jun and heat shock protein after transient cerebral ischemia in gerbils.
Ischemic Attack, Transient
[Dynamic cellular response following brain ischemia and reperfusion]
Ischemic Stroke
Correlation of lymphocyte heat shock protein 70 levels with neurologic deficits in elderly patients with cerebral infarction.
Ischemic Stroke
Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1.
Ischemic Stroke
Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B.
Ischemic Stroke
EF1A1/HSC70 Cooperatively Suppress Brain Endothelial Cell Apoptosis via Regulating JNK Activity.
Ischemic Stroke
Effects of polymorphisms of heat shock protein 70 gene on ischemic stroke, and interaction with smoking in China.
Ischemic Stroke
Exploring molecular mechanism underlying Chinese medicine syndrome: A study on correlation between Chinese medicine syndrome and biomarkers for ischemic stroke.
Ischemic Stroke
GRP78 Promotes Neural Stem Cell Antiapoptosis and Survival in Response to Oxygen-Glucose Deprivation (OGD)/Reoxygenation through PI3K/Akt, ERK1/2, and NF-?B/p65 Pathways.
Ischemic Stroke
Heat shock protein 27 as a neuroprotective biomarker and a suitable target for stem cell therapy and pharmacotherapy in ischemic stroke.
Ischemic Stroke
Heat shock protein 90 inhibition by 17-Dimethylaminoethylamino-17-demethoxygeldanamycin protects blood-brain barrier integrity in cerebral ischemic stroke.
Ischemic Stroke
Heat shock protein A12A encodes a novel prosurvival pathway during ischaemic stroke.
Ischemic Stroke
HSPB8 overexpression prevents disruption of blood-brain barrier after intracerebral hemorrhage in rats through Akt/GSK3?/?-catenin signaling pathway.
Ischemic Stroke
Neurotherapeutic activity of the recombinant heat shock protein Hsp70 in a model of focal cerebral ischemia in rats.
Ischemic Stroke
Protecting against ischaemic stroke in rats by heat shock protein 20-mediated exercise.
Ischemic Stroke
Semi-quantitative analyses of hippocampal heat shock protein-70 expression based on the duration of ischemia and the volume of cerebral infarction in mice.
Ischemic Stroke
Serum levels of heat shock protein 27 in patients with acute ischemic stroke.
Ischemic Stroke
Stem Cell-Like Dog Placenta Cells Afford Neuroprotection against Ischemic Stroke Model via Heat Shock Protein Upregulation.
Ischemic Stroke
The Hsp90 Inhibitor 17-DMAG Attenuates Hyperglycemia-Enhanced Hemorrhagic Transformation in Experimental Stroke.
Ischemic Stroke
Toll-like receptors 2 and 4 in ischemic stroke: outcome and therapeutic values.
Ischemic Stroke
Up-regulation of miR-122 protects against neuronal cell death in ischemic stroke through the heat shock protein 70-dependent NF-?B pathway by targeting FOXO3.
Ischemic Stroke
[Study of genetic polymorphism of heat shock protein 70-1 associated with susceptibility to ischemic stroke]
Joint Diseases
Analysis of 70Kd heat shock protein expression in patients with internal derangement of the temporomandibular joint.
Kashin-Beck Disease
Decreased Expression of Heat Shock Protein 47 Is Associated with T-2 Toxin and Low Selenium-Induced Matrix Degradation in Cartilages of Kashin-Beck Disease.
Keloid
Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts.
Keloid
Effect of heat shock protein 47 on collagen accumulation in keloid fibroblast cells.
Keloid
Effect of heat shock protein 47 on collagen synthesis of keloid in vivo.
Keloid
Gene Expression of Neurotrophins and Their Receptors in Keloids.
Keloid
Heat Shock Protein 90 Inhibitor (17-AAG) Induces Apoptosis and Decreases Cell Migration/Motility of Keloid Fibroblasts.
Keloid
Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model.
Keloid
Heat shock proteins modulate keloid formation.
Keloid
Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts.
Keloid
HSP90 and TLR4 Interplay in Keloids.
Keloid
Modulation of heat shock protein 90 affects TGF-?-induced collagen synthesis in human dermal fibroblast cells.
Keloid
Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids.
Keloid
Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization.
Keloid
Reply: Heat Shock Protein 90 Inhibitor (17-AAG) Induces Apoptosis and Decreases Cell Migration Motility of Keloid Fibroblasts.
Keloid
Resveratrol inhibits fibrogenesis and induces apoptosis in keloid fibroblasts.
Keloid
Stress chaperone mortalin regulates human melanogenesis.
Keloid
Upregulation of HSP47 and collagen type III in the dermal fibrotic disease, keloid.
Keloid
[Detection of expression of heat shock protein 47 mRNA in pathological scar tissue by using real-time fluorescent quantitative RT-PCR]
Keratoacanthoma
CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.
Keratoconjunctivitis
Heat shock protein expression in human conjunctiva.
Keratoconus
Expression of wound healing and stress-related proteins in keratoconus corneas.
Kidney Calculi
Characterizations of HSP90-Interacting Complex in Renal Cells Using Tandem Affinity Purification and Its Potential Role in Kidney Stone Formation.
Kidney Cortex Necrosis
Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal.
Kidney Diseases
Bi-allelic pathogenic variations in DNAJB11 cause Ivemark II syndrome, a renal-hepatic-pancreatic dysplasia.
Kidney Diseases
Endoplasmic reticulum stress in UMOD-related kidney disease: a human pathologic study.
Kidney Diseases
Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal.
Kidney Diseases
The role of heat shock proteins in kidney disease.
Kidney Diseases
Urinary Biomarkers Indicative of Apoptosis and Acute Kidney Injury in the Critically Ill.
Kidney Diseases, Cystic
A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector.
Kidney Diseases, Cystic
Bi-allelic pathogenic variations in DNAJB11 cause Ivemark II syndrome, a renal-hepatic-pancreatic dysplasia.
Kidney Failure, Chronic
Heat shock protein (HSP) expression and proliferation of tubular cells in end stage renal disease with and without haemodialysis.
Kidney Neoplasms
17-Allylamino-17-demethoxygeldanamycin and ritonavir inhibit renal cancer growth by inhibiting the expression of heat shock factor-1.
Kidney Neoplasms
Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 1.
Kidney Neoplasms
Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy.
Kidney Neoplasms
Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells.
Kidney Neoplasms
Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients.
Kidney Neoplasms
HSP60 silencing promotes Warburg-like phenotypes and switches the mitochondrial function from ATP production to biosynthesis in ccRCC cells.
Kidney Neoplasms
Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects.
Kyphosis
Positron emission tomography in juvenile Alexander disease.
Labyrinth Diseases
A systematic review and meta-analysis of the diagnostic accuracy of anti-heat shock protein 70 antibodies for the detection of autoimmune hearing loss.
Labyrinth Diseases
Comparison of anti-heat shock protein 70 (anti-hsp70) and anti-68-kDa inner ear protein in the sera of patients with Meniere's disease.
Labyrinth Diseases
Expression of heat shock protein 70 in the cochlea in experimental autoimmune inner ear disease.
Labyrinth Diseases
Recognition of a dominant epitope in bovine heat-shock protein 70 in inner ear disease.
Labyrinth Diseases
Validity of the Western blot immunoassay for heat shock protein-70 in associated and isolated immunorelated inner ear disease.
Labyrinth Diseases
[The role of heat shock protein 70 and its autoantibody in experimental autoimmune inner ear disease]
Lambert-Eaton Myasthenic Syndrome
GRP78 antibodies damage the blood-brain barrier and relate to cerebellar degeneration in Lambert-Eaton myasthenic syndrome.
Laryngeal Neoplasms
Effect of pepsin on laryngeal stress protein (Sep70, Sep53, and Hsp70) response: role in laryngopharyngeal reflux disease.
Laryngeal Neoplasms
Overexpression of human 27 kDa heat shock protein in laryngeal cancer cells confers chemoresistance associated with cell growth delay.
Laryngeal Neoplasms
Role of Krüppel-like factor 4 and heat shock protein 27 in cancer of the larynx.
Laryngeal Neoplasms
[Comparative study of expression levels of the major human heat shock proteins in cancer and normal tissues]
Laryngeal Neoplasms
[Expression of heat shock proteins in laryngeal carcinoma]
Laryngopharyngeal Reflux
Effect of pepsin on laryngeal stress protein (Sep70, Sep53, and Hsp70) response: role in laryngopharyngeal reflux disease.
Laryngopharyngeal Reflux
Effects of pepsin A on heat shock protein 70 response in laryngopharyngeal reflux patients with chronic rhinosinusitis.
Laryngopharyngeal Reflux
Expression of CAIII and Hsp70 Is Increased the Mucous Membrane of the Posterior Commissure in Laryngopharyngeal Reflux Disease.
Latent Tuberculosis
Generation of a T cell receptor (TCR)-like single domain antibody (sDAb) against a Mycobacterium Tuberculosis (Mtb) heat shock protein (HSP) 16kDa antigen presented by Human Leukocyte Antigen (HLA)-A*02.
Latent Tuberculosis
Insights into Macrophage Autophagy in Latent Tuberculosis Infection: Role of Heat Shock Protein 16.3.
Latent Tuberculosis
Optimisation of human VH domain antibodies specific to Mycobacterium tuberculosis heat shock protein (HSP16.3).
Legionellosis
Human and guinea pig immune responses to Legionella pneumophila protein antigens OmpS and Hsp60.
Legionnaires' Disease
Surface-associated heat shock proteins of Legionella pneumophila and Helicobacter pylori: roles in pathogenesis and immunity.
Leigh Disease
SURF1 related Leigh syndrome: Clinical and molecular findings of 16 patients from Turkey.
Leiomyoma
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Leiomyoma
Genistein suppresses spontaneous oviduct tumorigenesis in quail.
Leiomyoma
The effects of selenium supplementation on the spontaneously occurring fibroid tumors of oviduct, 8-hydroxy-2'-deoxyguanosine levels, and heat shock protein 70 response in Japanese quail.
Leiomyoma
Zinc picolinate in the prevention of leiomyoma in Japanese quail.
Leiomyosarcoma
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Leishmaniasis
Analysis of the antigenic properties of the L. infantum Hsp70: design of synthetic peptides for specific serodiagnosis of human leishmaniasis.
Leishmaniasis
Antigen-reactive gamma delta T cells in human leishmaniasis.
Leishmaniasis
Epitope mapping of the HSP83.1 protein of Leishmania braziliensis discloses novel targets for immunodiagnosis of tegumentary and visceral clinical forms of leishmaniasis.
Leishmaniasis
Functional alterations in macrophages after hypoxia selection.
Leishmaniasis
Heat shock protein 90 from neglected protozoan parasites.
Leishmaniasis
Hypoxia modulates expression of the 70-kD heat shock protein and reduces Leishmania infection in macrophages.
Leishmaniasis
Leishmania infantum heat shock protein 83 for the serodiagnosis of tegumentary leishmaniasis.
Leishmaniasis
Leishmania major: molecular cloning, sequencing, and expression of the heat shock protein 60 gene reveals unique carboxy terminal peptide sequences.
Leishmaniasis
Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana.
Leishmaniasis, Cutaneous
17-AAG-Induced Activation of the Autophagic Pathway in Leishmania Is Associated with Parasite Death.
Leishmaniasis, Cutaneous
Development and validation of PCR-based assays for diagnosis of American cutaneous leishmaniasis and identificatio nof the parasite species.
Leishmaniasis, Cutaneous
Leishmania major heat shock protein 70 (HSP70) is not protective in murine models of cutaneous leishmaniasis and stimulates strong humoral responses in cutaneous and visceral leishmaniasis patients.
Leishmaniasis, Diffuse Cutaneous
Association of Leishmania heat shock protein 83 antigen and immunoglobulin G4 antibody titers in Brazilian patients with diffuse cutaneous leishmaniasis.
Leishmaniasis, Mucocutaneous
Leishmania infantum heat shock protein 83 for the serodiagnosis of tegumentary leishmaniasis.
Leishmaniasis, Visceral
Antibodies to Leishmania donovani infantum heat-shock protein 70 in human visceral leishmaniasis.
Leishmaniasis, Visceral
Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis.
Leishmaniasis, Visceral
Epitope mapping of the HSP83.1 protein of Leishmania braziliensis discloses novel targets for immunodiagnosis of tegumentary and visceral clinical forms of leishmaniasis.
Leishmaniasis, Visceral
Leishmania major heat shock protein 70 (HSP70) is not protective in murine models of cutaneous leishmaniasis and stimulates strong humoral responses in cutaneous and visceral leishmaniasis patients.
Leishmaniasis, Visceral
Recombinant Leishmania Hsp90 and Hsp70 are recognized by sera from visceral leishmaniasis patients but not Chagas' disease patients.
Leishmaniasis, Visceral
Recombinant Leishmania infantum Heat Shock Protein 83 for the Serodiagnosis of Cutaneous, Mucosal, and Visceral Leishmaniasis.
Leishmaniasis, Visceral
RFLPs of ITS, ITS1 and hsp70 amplicons and sequencing of ITS1 of recent clinical isolates of Kala-azar from India and Bangladesh confirms the association of L. tropica with the disease.
Leishmaniasis, Visceral
Ribosome Profiling Reveals HSP90 Inhibitor Effects on Stage-Specific Protein Synthesis in Leishmania donovani.
Lentivirus Infections
[The effect of astragalus injection on the expression of endoplasmic reticulum stress chaperonin GRP78 and GRP94 mRNA in adriamycin-injured cardiomyocytes with calumenin silencing by shRNA].
Lentivirus Infections
[The relationship between miRNA378, calumenin and endoplasmic reticulum stress in suckling mouse myocardium with myocarditis caused by adriamycin].
Leprosy
Anti-peripheral nerve antibodies in leprosy patients recognize an epitope shared by the M. leprae 65 kDa heat shock protein.
Leprosy
Characterization of circulating immune complexes in leprosy patients and their correlation with specific antibodies against Mycobacterium leprae.
Leprosy
Cross-reactivity of anti-10kD heat shock protein antibodies in leprosy and tuberculosis patients.
Leprosy
Effects of anti-endothelial cell antibodies in leprosy and malaria.
Leprosy
Fibronectin-binding antigen 85 and the 10-kilodalton GroES-related heat shock protein are the predominant TH-1 response inducers in leprosy contacts.
Leprosy
Functional characterization of a small heat shock protein from Mycobacterium leprae.
Leprosy
Identification of a Mycobacterium leprae-specific T cell epitope on the 70 kDa heat shock protein.
Leprosy
IgM anti-phenolic glycolipid I and IgG anti-10-kDa heat shock protein antibodies in sera and immune complexes isolated from leprosy patients with or without erythema nodosum leprosum and contacts.
Leprosy
Lysis of autologous macrophages pulsed with hsp10 from Mycobacterium leprae is associated to the absence of bacilli in leprosy.
Leprosy
Nerve and skin damage in leprosy is associated with increased intralesional heat shock protein.
Leprosy
Polymorphism in heat-shock protein 70-1 (HSP70-1) gene promoter region and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians.
Leprosy
Sequence and expression of the Mycobacterium leprae dnaJ gene.
Leprosy, Lepromatous
Mycobacteria contain two groEL genes: the second Mycobacterium leprae groEL gene is arranged in an operon with groES.
Leprosy, Multibacillary
Interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) are necessary in the early stages of induction of CD4 and CD8 cytotoxic T cells by Mycobacterium leprae heat shock protein (hsp) 65 kD.
Leprosy, Multibacillary
Lack of cytotoxic activity against Mycobacterium leprae 65-kD heat shock protein (hsp) in multibacillary leprosy patients.
Leprosy, Tuberculoid
Conserved TcR beta chain usage for a single MHC class II-restricted heat shock protein peptide.
Leptospirosis
AAA+ Molecular Chaperone ClpB in Leptospira interrogans: Its Role and Significance in Leptospiral Virulence and Pathogenesis of Leptospirosis.
Leptospirosis
Cloning, expression, and homology modeling of GroEL protein from Leptospira interrogans serovar autumnalis strain N2.
Leptospirosis
GroEL protein of the Leptospira spp. interacts with host proteins and induces cytokines secretion on macrophages.
Leptospirosis
Surface-associated Hsp60 chaperonin of Leptospira interrogans serovar Autumnalis N2 strain as an immunoreactive protein.
Leukemia
28-kDa mammalian heat shock protein, a novel substrate of a growth regulatory protease involved in differentiation of human leukemia cells.
Leukemia
5-Episinuleptolide Acetate, a Norcembranoidal Diterpene from the Formosan Soft Coral Sinularia sp., Induces Leukemia Cell Apoptosis through Hsp90 Inhibition.
Leukemia
A Mitochondrial-targeted purine-based HSP90 antagonist for leukemia therapy.
Leukemia
A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo.
Leukemia
Aberrant protein expression in cerebral cortex of fetus with Down syndrome.
Leukemia
Analysis of cell surface and relative gene expression of heat shock protein 70 in human leukemia cell lines.
Leukemia
Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy.
Leukemia
Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via beta-catenin/TCF7L2 pathway in adult T cell leukemia cells.
Leukemia
Attenuation of the induced differentiation of HL-60 leukemia cells by mitochondrial chaperone HSP70.
Leukemia
BIIB021, an Hsp90 inhibitor: A promising therapeutic strategy for blood malignancies (Review).
Leukemia
Caspase-dependent, geldanamycin-enhanced cleavage of co-chaperone p23 in leukemic apoptosis.
Leukemia
Clinical correlation of circulating heat shock protein 70 in acute leukemia.
Leukemia
Clonogenicity of human leukemic cells protected from cell-lethal agents by heat shock protein 70.
Leukemia
Coadministration of the heat shock protein 90 antagonist 17-allylamino- 17-demethoxygeldanamycin with suberoylanilide hydroxamic acid or sodium butyrate synergistically induces apoptosis in human leukemia cells.
Leukemia
Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.
Leukemia
Combined use of dendritic cells enhances specific antileukemia immunity by leukemia cell-derived heat shock protein 70 in a mouse model with minimal residual leukemia cells.
Leukemia
Correlation between HSP90 induction kinetics in murine leukemia cells and the amount of cisplatin over a wide range of cytostatic concentrations.
Leukemia
Cotreatment with 17-allylamino-demethoxygeldanamycin and FLT-3 kinase inhibitor PKC412 is highly effective against human acute myelogenous leukemia cells with mutant FLT-3.
Leukemia
Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change.
Leukemia
Curcumin derivative C212 inhibits Hsp90 and eliminates both growing and quiescent leukemia cells in deep dormancy.
Leukemia
Current Understanding of HSP90 as a Novel Therapeutic Target: An Emerging Approach for the Treatment of Cancer.
Leukemia
Dendritic cells pulsed with leukemia cell-derived exosomes more efficiently induce antileukemic immunities.
Leukemia
Deregulated expression of the HSP40 family members Auxilin-1 and -2 is indicative of proteostasis imbalance and predicts patient outcome in Ph(+) leukemia.
Leukemia
Differential expression of immune system-related components in midtrimester amniotic fluid from singleton and twin pregnancies.
Leukemia
Dinaciclib (SCH727965) Inhibits the Unfolded Protein Response through a CDK1- and 5-Dependent Mechanism.
Leukemia
Disruption of the Bcr-Abl/Hsp90 protein complex: a possible mechanism to inhibit Bcr-Abl-positive human leukemic blasts by novobiocin.
Leukemia
Down-regulation of a Mr 90,000 heat shock cognate protein during granulocytic differentiation in HL-60 human leukemia cells.
Leukemia
Effect of ELF-EMF on number of apoptotic cells; correlation with reactive oxygen species and HSP.
Leukemia
Effect of recombinant heat shock protein 70 of mycobacterial origin on cytotoxic activity and immunophenotype of human peripheral blood mononuclear leukocytes.
Leukemia
Effectiveness of HSV-tk suicide gene therapy driven by the Grp78 stress-inducible promoter in esophagogastric junction and gastric adenocarcinomas.
Leukemia
Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway.
Leukemia
Effects of extremely low frequency magnetic fields on NGF induced neuronal differentiation of PC12 cells.
Leukemia
Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter.
Leukemia
Evolutionary significance of intra-genome duplications on human chromosomes.
Leukemia
Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding.
Leukemia
F1F0-ATP synthase functions as a co-chaperone of Hsp90-substrate protein complexes.
Leukemia
FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases.
Leukemia
Geldanamycin and its anti-cancer activities.
Leukemia
GRP78-targeted in-silico virtual screening of novel anticancer agents.
Leukemia
HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.
Leukemia
HDN-1 induces cell differentiation toward apoptosis in promyelocytic leukemia cells depending on its selective effect on client proteins of Hsp90.
Leukemia
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.
Leukemia
Heat shock protein 90 and role of its chemical inhibitors in treatment of hematologic malignancies.
Leukemia
Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells.
Leukemia
Heat shock protein 90 interacts with vitamin D receptor in human leukemia cells.
Leukemia
Heat shock protein 90 regulates the expression of Wilms' tumor 1 protein in myeloid leukemias.
Leukemia
Heat shock protein 90.
Leukemia
Heat shock protein 90: a potential therapeutic target in leukemic progenitor and stem cells harboring mutant BCR-ABL resistant to kinase inhibitors.
Leukemia
Heat-shock protein expression in leukemia.
Leukemia
High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells.
Leukemia
High expression of heat shock protein 90 alpha and its significance in human acute leukemia cells.
Leukemia
Homoharringtonine Combined with the Heat Shock Protein 90 Inhibitor IPI504 in the Treatment of FLT3-ITD Acute Myeloid Leukemia.
Leukemia
Hsp27 expression in neuroblastoma: correlation with disease stage.
Leukemia
Hsp90 cleavage by an oxidative stress leads to its client proteins degradation and cancer cell death.
Leukemia
HSP90 inhibitor 17AAG causes apoptosis in ATRA-resistant acute promyelocytic leukemia cells.
Leukemia
HSP90 inhibitor AUY922 induces cell death by disruption of the Bcr-Abl, Jak2 and HSP90 signaling network complex in leukemia cells.
Leukemia
HSP90 inhibitor NVP-BEP800 affects stability of SRC kinases and growth of T-cell and B-cell acute lymphoblastic leukemias.
Leukemia
HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way.
Leukemia
Hsp90 inhibitors and drug resistance in cancer: The potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs.
Leukemia
Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells.
Leukemia
Hsp90-mediated inactivation of NF{kappa}B switches autophagy to apoptosis through becn1 transcriptional inhibition in selenite-induced NB4 cells.
Leukemia
Human leukemias with mutated FLT3 kinase are synergistically sensitive to FLT3 and Hsp90 inhibitors: the key role of the STAT5 signal transduction pathway.
Leukemia
Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70.
Leukemia
Identification and characterization of a 66-68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells.
Leukemia
Identification of an overexpressed gene, HSPA4L, the product of which can provoke prevalent humoral immune responses in leukemia patients.
Leukemia
Identification of mixed lineage leukemia 1(MLL1) protein as a coactivator of heat shock factor 1(HSF1) protein in response to heat shock protein 90 (HSP90) inhibition.
Leukemia
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Leukemia
IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.
Leukemia
Impact of USP8 Gene Mutations on Protein Deregulation in Cushing Disease.
Leukemia
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Leukemia
Induction of human hsp60 expression in monocytic cell lines.
Leukemia
Influence of rate of heating on thermosensitivity of L1210 leukemia: membrane lipids and Mr 70,000 heat shock protein.
Leukemia
Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells.
Leukemia
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.
Leukemia
Inhibition of the mTORC2 and chaperone pathways to treat leukemia.
Leukemia
Initial testing (stage 1) of ganetespib, an Hsp90 inhibitor, by the pediatric preclinical testing program.
Leukemia
Interleukin (IL)-6 signaling leads to phosphorylation of the small heat shock protein (Hsp)27 through activation of the MAP kinase and MAPKAP kinase 2 pathway in monocytes and monocytic leukemia cells.
Leukemia
Interleukin-3 and granulocyte-macrophage colony-stimulating factor induce activation of the MAPKAP kinase 2 resulting in in vitro serine phosphorylation of the small heat shock protein (Hsp 27).
Leukemia
Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2?/ATF4 axis in selenite-treated NB4 cells.
Leukemia
Isolation of MHC class I-restricted tumor antigen peptide and its precursors associated with heat shock proteins hsp70, hsp90, and gp96.
Leukemia
Leukemia inhibitory factor promotes Hsp90 association with STAT3 in mouse embryonic stem cells.
Leukemia
LSK derived LSK- cells have a high apoptotic rate related to survival regulation of hematopoietic and leukemic stem cells.
Leukemia
Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells.
Leukemia
Modulating Heat Shock Proteins 70 and 90 Expression by Low Power Laser Irradiation (635nm and 780nm) in Jurkat E6.1 T-lymphocyte Leukemia Cell Line.
Leukemia
Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.
Leukemia
Mortalin inhibitors sensitize K562 leukemia cells to complement-dependent cytotoxicity.
Leukemia
Neferine in the Lotus Plumule Potentiates the Antitumor Effect of Imatinib in Primary Chronic Myeloid Leukemia Cells In Vitro.
Leukemia
Neuronal intranuclear inclusion disease without polyglutamine inclusions in a child.
Leukemia
Phase I and pharmacological study of cytarabine and tanespimycin in relapsed and refractory acute leukemia.
Leukemia
Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in Mice.
Leukemia
Possible effects of early treatments of hsp90 inhibitors on preventing the evolution of drug resistance to other anti-cancer drugs.
Leukemia
Power-line frequency electromagnetic fields do not induce changes in phosphorylation, localization, or expression of the 27-kilodalton heat shock protein in human keratinocytes.
Leukemia
Proliferation of hematopoietic cells is accompanied by suppressed expression of heat shock protein 70.
Leukemia
Proteasome inhibitor-induced cleavage of HSP90 is mediated by ROS generation and caspase 10-activation in human leukemic cells.
Leukemia
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.
Leukemia
Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors.
Leukemia
SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells.
Leukemia
Solid lipid nanoparticles as a novel formulation approach for tanespimycin (17-AAG) against leishmania infections: Preparation, characterization and macrophage uptake.
Leukemia
Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells.
Leukemia
Study of heat shock protein HSP90 alpha, HSP70, HSP27 mRNA expression in human acute leukemia cells.
Leukemia
Suberoylanilide hydroxamic acid induces ROS-mediated cleavage of HSP90 in leukemia cells.
Leukemia
Superior activity of the combination of histone deacetylase inhibitor LAQ824 and the FLT-3 kinase inhibitor PKC412 against human acute myelogenous leukemia cells with mutant FLT-3.
Leukemia
SUV39H1 is a New Client Protein of Hsp90 Degradated by Chaetocin as a Novel C-Terminal Inhibitor of Hsp90.
Leukemia
Synergism between etoposide and 17-AAG in leukemia cells: critical roles for Hsp90, FLT3, topoisomerase II, Chk1, and Rad51.
Leukemia
Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.
Leukemia
Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways.
Leukemia
Synergistic Interactions between DMAG and Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitors in Bcr/abl+ Leukemia Cells Sensitive and Resistant to Imatinib Mesylate.
Leukemia
Targeting heat shock protein 90 with non-quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma.
Leukemia
Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C.
Leukemia
Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response.
Leukemia
The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy.
Leukemia
The Hsp90 inhibitor SNX-7081 is synergistic with fludarabine nucleoside via DNA damage and repair mechanisms in human, p53-negative chronic lymphocytic leukemia.
Leukemia
The preparation of leukemia cell vaccine expressing BCG heat shock protein 70 and anti-leukemia effect in vitro.
Leukemia
The synthetic heat shock protein 90 (Hsp90) inhibitor EC141 induces degradation of Bcr-Abl p190 protein and apoptosis of Ph-positive acute lymphoblastic leukemia cells.
Leukemia
The transcription factor Wilms tumor 1 confers resistance in myeloid leukemia cells against the proapoptotic therapeutic agent TRAIL by regulating the antiapoptotic protein Bcl-xL.
Leukemia
Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.
Leukemia
Tricyclic series of heat shock protein 90 (Hsp90) inhibitors part I: discovery of tricyclic imidazo[4,5-c]pyridines as potent inhibitors of the Hsp90 molecular chaperone.
Leukemia
Tumor-derived multiple chaperone enrichment by free-solution isoelectric focusing yields potent antitumor vaccines.
Leukemia
Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.
Leukemia
Tyrosine phosphorylation of HSC70 and its interaction with RFC mediates methotrexate resistance in murine L1210 leukemia cells.
Leukemia
Use of the glucose starvation-inducible glucose-regulated protein 78 promoter in suicide gene therapy of murine fibrosarcoma.
Leukemia
VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition.
Leukemia
Y-632 inhibits Hsp90 function through disrupting the interaction of Hsp90-Hop and exerts antitumor activity in vitro and in vivo.
Leukemia
ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia.
Leukemia
[CD133 epitope vaccine with gp96 as adjuvant elicits an antitumor T cell response against leukemia].
Leukemia
[Expression and Significance of PD-L1, HSP90 and HSP90? in Serum of Patients with Acute Leukemia].
Leukemia
[Expression characteristics of heat shock protein 70 and pim-1 gene in bone marrow mononuclear cells from leukemia patients and their clinical significance]
Leukemia
[Gene Expression Profile of Apoptosis in Leukemia Cells Induced by Hsp90 Selective inhibitor 17-AAG].
Leukemia
[Preparation of Heat Shock Protein 70 (Hsp70) and Idiotypic Determinant Single-chain Antibody (Id-ScFv) in a Patient with B-cell Chronic Lymphatic Leukemia (B-CLL) and Antitumor Effect of Peptide Complex Hsp70-Id.]
Leukemia
[Proliferation and Apoptosis of Leukemia Cell Line K562 Treated with HSP90 Inhibitor 17-DMAG].
Leukemia
[Study on signal transduction pathway in differentiation and apoptosis of leukemia cells induced by heat shock protein inhibitor]
Leukemia
[Thapsigargin-induced apoptosis of K562 cells and its mechanism.]
Leukemia
[The Hsp90 inhibitor FW-04-806 suppresses Bcr/Abl-mediated growth of leukemia cells by inhibiting proliferation and inducing apoptosis].
Leukemia
[The mechanism of apoptosis of chronic myeloid leukemia cells induced by the novel p210 bcr/abl inhibitor berbamine]
Leukemia L1210
Tyrosine phosphorylation of HSC70 and its interaction with RFC mediates methotrexate resistance in murine L1210 leukemia cells.
Leukemia, B-Cell
AIDing cancer treatment: Reducing AID activity via HSP90 inhibition.
Leukemia, B-Cell
Cytotoxicity and expression of genes involved in the cellular stress response and apoptosis in mammalian fibroblast exposed to cotton cellulose nanofibers.
Leukemia, B-Cell
Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34-positive compartment.
Leukemia, Erythroblastic, Acute
Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Antiproliferative prostaglandins activate heat shock transcription factor.
Leukemia, Erythroblastic, Acute
Contribution of heat shock proteins to cell protection from complement-mediated lysis.
Leukemia, Erythroblastic, Acute
Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9.
Leukemia, Erythroblastic, Acute
Correlation between HSP90 induction kinetics in murine leukemia cells and the amount of cisplatin over a wide range of cytostatic concentrations.
Leukemia, Erythroblastic, Acute
Hemin-induced transcriptional activation of the HSP70 gene during erythroid maturation in K562 cells is due to a heat shock factor-mediated stress response.
Leukemia, Erythroblastic, Acute
Mortalin/Grp75 Binds to Complement C9 and Plays a Role in Resistance to Complement-Dependent Cytotoxicity.
Leukemia, Erythroblastic, Acute
Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells.
Leukemia, Erythroblastic, Acute
Reduction of Thermotolerance by Heat Shock Protein 90 Inhibitors in Murine Erythroleukemia Cells.
Leukemia, Lymphocytic, Chronic, B-Cell
17-DMAG targets the NF-{kappa}B family of proteins to induce apoptosis in CLL: clinical implications of HSP90 inhibition.
Leukemia, Lymphocytic, Chronic, B-Cell
A phase I trial of the intravenous Hsp90 inhibitor alvespimycin (17-DMAG) in patients with relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma.
Leukemia, Lymphocytic, Chronic, B-Cell
Abundance of heat shock proteins (hsp89, hsp60, and hsp27) in malignant cells of Hodgkin's disease.
Leukemia, Lymphocytic, Chronic, B-Cell
Association of GRP78, HIF-1? and BAG3 Expression with the Severity of Chronic Lymphocytic Leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Differential heat shock protein localization in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding.
Leukemia, Lymphocytic, Chronic, B-Cell
Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs.
Leukemia, Lymphocytic, Chronic, B-Cell
Heat shock protein-90 inhibitor, NVP-AUY922, is effective in combination with fludarabine against chronic lymphocytic leukemia cells cultured on CD40L-stromal layer and inhibits their activated/proliferative phenotype.
Leukemia, Lymphocytic, Chronic, B-Cell
HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Hsp90 Inhibitor SNX-7081 Dysregulates Proteins Involved with DNA Repair and Replication and the Cell Cycle in Human Chronic Lymphocytic Leukemia (CLL) Cells.
Leukemia, Lymphocytic, Chronic, B-Cell
HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Molecular Pathways: GLI1-Induced Drug Glucuronidation in Resistant Cancer Cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.
Leukemia, Lymphocytic, Chronic, B-Cell
Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
The Hsp90 inhibitor SNX-7081 is synergistic with fludarabine nucleoside via DNA damage and repair mechanisms in human, p53-negative chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
The Hsp90 inhibitor SNX-7081 synergizes with and restores sensitivity to fludarabine in chronic lymphocytic leukemia cells with lesions in the TP53 pathway: a potential treatment strategy for fludarabine refractory disease.
Leukemia, Lymphocytic, Chronic, B-Cell
TLR9-activating DNA up-regulates ZAP70 via sustained PKB induction in IgM+ B cells.
Leukemia, Lymphocytic, Chronic, B-Cell
ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
[Preparation of Heat Shock Protein 70 (Hsp70) and Idiotypic Determinant Single-chain Antibody (Id-ScFv) in a Patient with B-cell Chronic Lymphatic Leukemia (B-CLL) and Antitumor Effect of Peptide Complex Hsp70-Id.]
Leukemia, Lymphoid
Enhancement of immunogenicity of murine lymphocytic leukemia cells by transfection with BCG heat shock protein 70 gene.
Leukemia, Lymphoid
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Activation of NK cells by extracellular heat shock protein 70 through induction of NKG2D ligands on dendritic cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Bag1 directly routes immature BCR-ABL for proteasomal degradation.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
BJ-B11, a novel Hsp90 inhibitor, induces apoptosis in human chronic myeloid leukemia K562 cells through the mitochondria-dependent pathway.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
C1206, a novel curcumin derivative, potently inhibits Hsp90 and human chronic myeloid leukemia cells in vitro.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
CAMKII?, HSP70 and HSP90 transcripts are differentially expressed in chronic myeloid leukemia cells from patients with resistant mutated disease.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Celastrol, a novel HSP90 inhibitor, depletes Bcr-Abl and induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cell cycle arrest, apoptosis and autophagy induced by iminosugars on K562 cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Circulating heat shock protein 70 and progression in patients with chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Combination of imatinib mesylate with autologous leukocyte-derived heat shock protein and chronic myelogenous leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Combination of JAK2 and HSP90 inhibitors: an effective therapeutic option in drug-resistant chronic myelogenous leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Extracellular heat shock protein 70: a potential prognostic marker for chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hot off the Press.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hsp90 Inhibitors for the Treatment of Chronic Myeloid Leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Modulation of Akt and ERK1/2 pathways by resveratrol in chronic myelogenous leukemia (CML) cells results in the downregulation of Hsp70.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Nonsteroidal Anti-inflammatory Drugs Sensitize CD44-Overexpressing Cancer Cells to Hsp90 Inhibitor Through Autophagy Activation.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Overexpression of the heat-shock protein 70 is associated to imatinib resistance in chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Sensitization of chemo-resistant human chronic myeloid leukemia stem-like cells to Hsp90 inhibitor by SIRT1 inhibition.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Targeting HSPA8 inhibits proliferation via downregulating BCR-ABL and enhances chemosensitivity in imatinib-resistant chronic myeloid leukemia cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Effect of Heat Stress on Expression of gp96 in K562 Cell Line of the Chronic Myeloid Leukemia and Its Significance.]
Leukemia, Myeloid
Expression and phosphorylation of BiP/GRP78, a molecular chaperone in the endoplasmic reticulum, during the differentiation of a mouse myeloblastic cell line.
Leukemia, Myeloid
Heat sensitivity, thermotolerance, and profile of heat shock protein synthesis of human myelogenous leukemias.
Leukemia, Myeloid
Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells.
Leukemia, Myeloid
Heat shock protein 90 regulates the expression of Wilms' tumor 1 protein in myeloid leukemias.
Leukemia, Myeloid
Hsp90 Inhibition Reduces TLR5 Surface Expression and NF-?B Activation in Human Myeloid Leukemia THP-1 Cells.
Leukemia, Myeloid
Human Cytomegalovirus Stimulates the Synthesis of Select Akt-Dependent Antiapoptotic Proteins during Viral Entry To Promote Survival of Infected Monocytes.
Leukemia, Myeloid
Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31.
Leukemia, Myeloid
Low-dose irradiation induces expression of heat shock protein 70 mRNA and thermo- and radio-resistance in myeloid leukemia cell line.
Leukemia, Myeloid
Oxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperones.
Leukemia, Myeloid
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein.
Leukemia, Myeloid
Weak electromagnetic fields (50 Hz) elicit a stress response in human cells.
Leukemia, Myeloid, Acute
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species.
Leukemia, Myeloid, Acute
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
Leukemia, Myeloid, Acute
Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients.
Leukemia, Myeloid, Acute
Cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90.
Leukemia, Myeloid, Acute
Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: Serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.
Leukemia, Myeloid, Acute
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Leukemia, Myeloid, Acute
Expression of heat shock protein 70 and NKG2D ligands in acute myeloid leukemia cell lines.
Leukemia, Myeloid, Acute
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells.
Leukemia, Myeloid, Acute
Heat shock protein 90 - a potential target in the treatment of human acute myelogenous leukemia.
Leukemia, Myeloid, Acute
Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine.
Leukemia, Myeloid, Acute
Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia.
Leukemia, Myeloid, Acute
High HSPA8 expression predicts adverse outcomes of acute myeloid leukemia.
Leukemia, Myeloid, Acute
Homoharringtonine Combined with the Heat Shock Protein 90 Inhibitor IPI504 in the Treatment of FLT3-ITD Acute Myeloid Leukemia.
Leukemia, Myeloid, Acute
HSP27 protects AML cells against VP-16-induced apoptosis through modulation of p38 and c-Jun.
Leukemia, Myeloid, Acute
HSP90 inhibition depletes DNA repair proteins to sensitize acute myelogenous leukemia to nucleoside analog chemotherapeutics.
Leukemia, Myeloid, Acute
Hsp90 inhibitor induces KG-1a cell differentiation and apoptosis via Akt/NF-?B signaling.
Leukemia, Myeloid, Acute
Hsp90/C terminal Hsc70-interacting protein regulates the stability of Ikaros in acute myeloid leukemia cells.
Leukemia, Myeloid, Acute
Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70).
Leukemia, Myeloid, Acute
Immunogenic apoptosis in human acute myeloid leukemia (AML): primary human AML cells expose calreticulin and release heat shock protein (HSP) 70 and HSP90 during apoptosis.
Leukemia, Myeloid, Acute
Impact of the expression of P glycoprotein, the multidrug resistance-related protein, bcl-2, mutant p53, and heat shock protein 27 on response to induction therapy and long-term survival in patients with de novo acute myeloid leukemia.
Leukemia, Myeloid, Acute
Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors.
Leukemia, Myeloid, Acute
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Leukemia, Myeloid, Acute
Membrane-bound heat shock protein 70 (Hsp70) in acute myeloid leukemia: a tumor specific recognition structure for the cytolytic activity of autologous NK cells.
Leukemia, Myeloid, Acute
Pharmacokinetics and dose escalation of the heat shock protein inhibitor 17-allyamino-17-demethoxygeldanamycin in combination with bortezomib in relapsed or refractory acute myeloid leukemia.
Leukemia, Myeloid, Acute
Phase I study of the heat shock protein 90 inhibitor alvespimycin (KOS-1022, 17-DMAG) administered intravenously twice weekly to patients with acute myeloid leukemia.
Leukemia, Myeloid, Acute
Proliferation of hematopoietic cells is accompanied by suppressed expression of heat shock protein 70.
Leukemia, Myeloid, Acute
Selective KIT inhibitor KI-328 and HSP90 inhibitor show different potency against the type of KIT mutations recurrently identified in acute myeloid leukemia.
Leukemia, Myeloid, Acute
Stress-induced in vitro apoptosis of native human acute myelogenous leukemia (AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and low levels of heat shock protein 70 and 90.
Leukemia, Myeloid, Acute
Study of heat shock protein HSP90 alpha, HSP70, HSP27 mRNA expression in human acute leukemia cells.
Leukemia, Myeloid, Acute
Superior activity of the combination of histone deacetylase inhibitor LAQ824 and the FLT-3 kinase inhibitor PKC412 against human acute myelogenous leukemia cells with mutant FLT-3.
Leukemia, Myeloid, Acute
Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling.
Leukemia, Myeloid, Acute
Targeting on glycosylation of mutant FLT3 in acute myeloid leukemia.
Leukemia, Myeloid, Acute
The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine.
Leukemia, Myeloid, Acute
The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo.
Leukemia, Promyelocytic, Acute
HSP90 inhibitor 17AAG causes apoptosis in ATRA-resistant acute promyelocytic leukemia cells.
Leukemia, T-Cell
Anti-proliferative activity of heat shock protein (Hsp) 90 inhibitors via beta-catenin/TCF7L2 pathway in adult T cell leukemia cells.
Leukemia, T-Cell
HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-?B activation and HTLV-1 replication.
Leukemia, T-Cell
Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70.
Leukemia, T-Cell
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Leukemia, T-Cell
Inhibition of heat shock protein-90 modulates multiple functions required for survival of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells.
Leukemia, T-Cell
The synthetic peptide P-197 inhibits human T-cell leukemia virus type 1 envelope-mediated syncytium formation by a mechanism that is independent of Hsc70.
Leukemia-Lymphoma, Adult T-Cell
Efficiency of AUY922 in mice with adult T-cell leukemia/lymphoma.
Leukemia-Lymphoma, Adult T-Cell
Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia-lymphoma cells.
Leukemia-Lymphoma, Adult T-Cell
Inhibition of heat shock protein-90 modulates multiple functions required for survival of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells.
Leukocytosis
Dietary supplementation of brown seaweed (Sargassum latifolium) alleviates the environmental heat stress-induced toxicity in male Barki sheep (Ovis aries).
Leukocytosis
Dietary supplementation of Sargassum latifolium modulates thermo-respiratory response, inflammation, and oxidative stress in bacterial endotoxin-challenged male Barki sheep.
Leukodystrophy, Metachromatic
Evaluating the role of ARSA in Chinese patients with Parkinson's disease.
Leukopenia
Epidemiology, genetic variants and clinical course of natural infections with Anaplasma phagocytophilum in a dairy cattle herd.
Leukopenia
Molecular pathogenesis of myelodysplastic syndromes with deletion 5q.
Leukoplakia
Heat shock protein (HSP70) as a marker of epithelial dysplasia in oral dysplastic lesions: A clinicopathological study.
Leukoplakia
Positive association of glucose-regulated protein 78 during oral cancer progression and the prognostic value in oral precancerous lesions.
Leukoplakia
[Studies of heat shock protein 60 and heat shock protein 70 in oral lichen planus]
Leukoplakia, Oral
Detection of salivary heat shock protein 27 by enzyme-linked immunosorbent assay and its correlation with histopathology of oral leukoplakia.
Lewy Body Disease
Chaperone and anti-chaperone: two-faced synuclein as stimulator of synaptic evolution.
Leydig Cell Tumor
The rat 78,000 dalton glucose-regulated protein (GRP78) as a precursor for the rat steroidogenesis-activator polypeptide (SAP): the SAP coding sequence is homologous with the terminal end of GRP78.
Li-Fraumeni Syndrome
Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.
Li-Fraumeni Syndrome
Withdrawal: Hsp90 and PKM2 drive the expression of aromatase in Li-Fraumeni syndrome breast adipose stromal cells.
Lichen Planus, Oral
Expression of heat shock protein (HSP70) in oral lichen planus and non-dysplastic oral leucoplakia.
Lichen Planus, Oral
Heat shock protein expression in oral lichen planus.
Lichen Planus, Oral
Immunohistochemical analyses of survivin and heat shock protein 90 expression in patients with oral lichen planus.
Lichen Planus, Oral
Oral lichen planus: an immunohistochemical study of heat shock proteins (HSPs) and cytokeratins (CKs) and a unifying hypothesis of pathogenesis.
Lichen Planus, Oral
[Studies of heat shock protein 60 and heat shock protein 70 in oral lichen planus]
Liposarcoma
Acceleration of TDP43 and FUS/TLS protein expressions in the preconditioned hippocampus following repeated transient ischemia.
Liposarcoma
HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo.
Liposarcoma
Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid liposarcoma.
Liposarcoma
Tumor Suppression Efficacy of Heat Shock Protein 90 Inhibitor 17AAG in a Liposarcoma Mouse Model.
Liposarcoma, Myxoid
Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid liposarcoma.
Liposarcoma, Myxoid
Immunohistochemical Analysis of Expressions of RB1, CDK4, HSP90, cPLA2G4A, and CHMP2B Is Helpful in Distinction between Myxofibrosarcoma and Myxoid Liposarcoma.
Lissencephaly
NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.
Listeriosis
Evidence for the early recruitment of T-cell receptor gamma delta+ T cells during rat listeriosis.
Listeriosis
Listeria monocytogenes Uses LAP to Promote Bacterial Transepithelial Translocation, and Induces Expression of LAP Receptor Hsp60.
Listeriosis
The regulatory role of heat shock protein 70-reactive CD4+ T cells during rat listeriosis.
Liver Abscess, Amebic
Obtaining of three recombinant antigens of Entamoeba histolytica and evaluation of their immunogenic ability without adjuvant in a hamster model of immunoprotection.
Liver Cirrhosis
An Intronic Variant in the GRP78, a Stress-Associated Gene, Improves Prediction for Liver Cirrhosis in Persistent HBV Carriers.
Liver Cirrhosis
Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma.
Liver Cirrhosis
Circulating mortalin autoantibody--a new serological marker of liver cirrhosis.
Liver Cirrhosis
Enhanced expression of glucose-regulated protein 78 correlates with malondialdehyde levels during the formation of liver cirrhosis in rats.
Liver Cirrhosis
Express ELISA for detection of mortalin.
Liver Cirrhosis
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Liver Cirrhosis
Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70.
Liver Cirrhosis
Heat shock protein 47 as indispensible participant in liver fibrosis: Possible protective effect of lactoferrin.
Liver Cirrhosis
Heat shock protein 47 effects on hepatic stellate cell-associated receptors in hepatic fibrosis of Schistosoma japonicum-infected mice.
Liver Cirrhosis
Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.
Liver Cirrhosis
Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma.
Liver Cirrhosis
Increased expression of 78 kD glucose-regulated protein promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis.
Liver Cirrhosis
Inhibition of hepatic stellate cell proliferation by heat shock protein 90 inhibitors in vitro.
Liver Cirrhosis
Involvement of heat shock protein 47 in Schistosoma japonicum-induced hepatic fibrosis in mice.
Liver Cirrhosis
O-GlcNAcylation-dependent upregulation of HO1 triggers ammonia-induced oxidative stress and senescence in hepatic encephalopathy.
Liver Cirrhosis
The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice.
Liver Cirrhosis
TRAIL regulates collagen production through HSF1-dependent Hsp47 expression in activated hepatic stellate cells.
Liver Cirrhosis
[Effect and mechanism of total flavonoids of Lichi Semen on CCl_4-induced liver fibrosis in rats, and prediction of Q-marker].
Liver Cirrhosis, Biliary
Antibodies to mycobacterial 65-kD heat shock protein cross-react with the main mitochondrial antigens in patients with primary biliary cirrhosis.
Liver Cirrhosis, Biliary
Autoantibody against 70 kD heat shock protein in patients with autoimmune liver diseases.
Liver Cirrhosis, Biliary
Disease-specific cross-reactivity between mimicking peptides of heat shock protein of Mycobacterium gordonae and dominant epitope of E2 subunit of pyruvate dehydrogenase is common in Spanish but not British patients with primary biliary cirrhosis.
Liver Cirrhosis, Biliary
Endothelial nitric oxide synthase regulation is altered in pancreas from cirrhotic rats.
Liver Cirrhosis, Biliary
Immuno-gold electron microscopical detection of heat shock protein 60 (hsp60) in mitochondria of rat hepatocytes and myocardiocytes.
Liver Cirrhosis, Biliary
Sequence homologies between hsp60 and autoantigens.
Liver Diseases
Alcohol-induced Hsp90 acetylation is a novel driver of liver sinusoidal endothelial dysfunction and alcohol-related liver disease.
Liver Diseases
Autoantibody against 70 kD heat shock protein in patients with autoimmune liver diseases.
Liver Diseases
Biliary expression of heat shock protein: a non-specific feature of chronic cholestatic liver diseases.
Liver Diseases
Changes in tumor necrosis factor-?, heat shock protein 70, malondialdehyde, and superoxide dismutase in patients with different severities of alcoholic fatty liver disease: a prospective observational study.
Liver Diseases
Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study.
Liver Diseases
Circulating IgA antibody against a 65 kDa heat shock protein in acute alcoholic hepatitis.
Liver Diseases
Expression of P53 and HSP70 in Chronic Hepatitis, Liver Cirrhosis, and Early and Advanced Hepatocellular Carcinoma Tissues and Their Diagnostic Value in Hepatocellular Carcinoma: An Immunohistochemical Study.
Liver Diseases
Heat shock protein 90 inhibitor induces apoptosis and attenuates activation of hepatic stellate cells.
Liver Diseases
Hsp90 modulates PPAR? activity in a mouse model of nonalcoholic fatty liver disease.
Liver Diseases
Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury.
Liver Diseases
Inhibition of HSP90? Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System.
Liver Diseases
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice.
Liver Diseases
Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice.
Liver Diseases
Role of Exogenous Hsp72 on Liver Dysfunction during Sepsis.
Liver Diseases
Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease.
Liver Diseases
Silymarin attenuated nonalcoholic fatty liver disease through the regulation of endoplasmic reticulum stress proteins GRP78 and XBP-1 in mice.
Liver Diseases
The effects of long-duration, low-temperature ground transportation on physiological and biochemical indicators of stress in mice.
Liver Diseases
The ménage à trois of autophagy, lipid droplets and liver disease.
Liver Diseases, Alcoholic
Circulating IgA antibody against a 65 kDa heat shock protein in acute alcoholic hepatitis.
Liver Diseases, Alcoholic
Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation via Hsp90.
Liver Diseases, Alcoholic
Immunocytochemical detection of the 70-kd heat shock protein in alcoholic liver disease.
Liver Diseases, Alcoholic
Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury.
Liver Diseases, Alcoholic
Modification of heat shock protein 90 by 4-hydroxynonenal in a rat model of chronic alcoholic liver disease.
Liver Diseases, Alcoholic
Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function.
Liver Failure
Heat shock protein 70 genotypes HSPA1B and HSPA1L influence cytokine concentrations and interfere with outcome after major injury.
Liver Failure
HSP60 and CpG-DNA-oligonucleotides differentially regulate LPS-tolerance of hepatic Kupffer cells.
Liver Neoplasms
15-Lipoxygenase-1/15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells growth through protein kinase B and heat shock protein 90 complex activation.
Liver Neoplasms
Association of mortalin (HSPA9) with liver cancer metastasis and prediction for early tumor recurrence.
Liver Neoplasms
Biological characteristics of heat shock protein 90 in human liver cancer cells.
Liver Neoplasms
Circulating mortalin autoantibody--a new serological marker of liver cirrhosis.
Liver Neoplasms
Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells.
Liver Neoplasms
Expression of mortalin detected in human liver cancer by tissue microarrays.
Liver Neoplasms
Ganetespib radiosensitization for liver cancer therapy.
Liver Neoplasms
Gel-based proteomics of liver cancer progression in rat.
Liver Neoplasms
Glucose-regulated protein 78 demonstrates antiviral effects but is more suitable for hepatocellular carcinoma prevention in hepatitis B.
Liver Neoplasms
Granulin-epithelin precursor interacts with 78-kDa glucose-regulated protein in hepatocellular carcinoma.
Liver Neoplasms
GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Liver Neoplasms
Heat shock protein 90 inhibition abrogates hepatocellular cancer growth through cdc2-mediated G(2)/M cell cycle arrest and apoptosis.
Liver Neoplasms
Heat shock protein gp96 decreases p53 stability by regulating Mdm2 E3 ligase activity in liver cancer.
Liver Neoplasms
HSP90 and SIRT3 expression in hepatocellular carcinoma and their effect on invasive capability of human hepatocellular carcinoma cells.
Liver Neoplasms
Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta.
Liver Neoplasms
Identification of the Differential Expression Profiles of Serum and Tissue Proteins During Rat Hepatocarcinogenesis.
Liver Neoplasms
Immunogenic Cell Death (ICD) of Murine H22 Cells Induced by Lentinan.
Liver Neoplasms
Inhibition of heat-shock protein 90 sensitizes liver cancer stem-like cells to magnetic hyperthermia and enhances anti-tumor effect on hepatocellular carcinoma-burdened nude mice.
Liver Neoplasms
Mild Magnetic Hyperthermia-Activated Innate Immunity for Liver Cancer Therapy.
Liver Neoplasms
Plasma Heat Shock Protein 90alpha as a Biomarker for the Diagnosis of Liver Cancer: An Official, Large-scale, and Multicenter Clinical Trial.
Liver Neoplasms
Plasma heat shock protein 90alpha as a biomarker for the diagnosis of liver cancer: in patients with different clinicopathologic characteristics.
Liver Neoplasms
Radiofrequency ablation, heat shock protein 70 and potential anti-tumor immunity in hepatic and pancreatic cancers: a minireview.
Liver Neoplasms
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer.
Liver Neoplasms
Solid-phase synthesis, characterization and RNAi activity of branch and hyperbranch siRNAs.
Liver Neoplasms
Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing p53-mediated apoptosis in hepatocellular carcinoma.
Liver Neoplasms
The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
Liver Neoplasms
The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.
Liver Neoplasms
The Molecular Chaperone HSP70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA-Damage and MAPK/ERK Signaling Pathways.
Liver Neoplasms
[Regulatory mechanism of heat shock protein 90 on autophagy-related transcription factor EB in human hepatocellular carcinoma cells].
Liver Neoplasms, Experimental
Comparative proteomics of rat liver and Morris hepatoma 7777 plasma membranes.
Long QT Syndrome
Heat shock protein 70 gene polymorphisms' influence on the electrophysiology of long QT syndrome.
Low Tension Glaucoma
Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor.
Lung Diseases
Activation of the plasma kallikrein-kinin system on human lung epithelial cells.
Lung Diseases
Anti-citrullinated heat shock protein 90 antibodies identified in bronchoalveolar lavage fluid are a marker of lung-specific immune responses.
Lung Diseases
Expression of heme oxygenase-1 in type II pneumocytes protects against heatstroke-induced lung damage.
Lung Diseases
Hsp90 regulation of fibroblast activation in pulmonary fibrosis.
Lung Diseases
Immunolocalization of collagen and collagen-binding heat shock protein 47 in fibrotic lung diseases.
Lung Diseases
Serum heat shock protein 47 levels in patients with drug-induced lung disease.
Lung Diseases, Interstitial
Anti-citrullinated heat shock protein 90 antibodies identified in bronchoalveolar lavage fluid are a marker of lung-specific immune responses.
Lung Diseases, Interstitial
Autoreactive T cells to citrullinated HSP90 are associated with interstitial lung disease in rheumatoid arthritis.
Lung Diseases, Interstitial
Extensive Citrullination Promotes Immunogenicity of HSP90 through Protein Unfolding and Exposure of Cryptic Epitopes.
Lung Diseases, Interstitial
Identification of citrullinated heat shock protein 90 isoforms as novel autoantigens in rheumatoid arthritis-associated interstitial lung disease.
Lung Diseases, Interstitial
Spontaneous heat shock protein synthesis by alveolar macrophages in interstitial lung disease associated with phagocytosis of eosinophils.
Lung Injury
Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1.
Lung Injury
Do we kNOw how HSP90 and eNOS mediate lung injury in sickle cell disease?
Lung Injury
Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome.
Lung Injury
Enhanced Hsp70 expression protects against acute lung injury by modulating apoptotic pathways.
Lung Injury
Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expression.
Lung Injury
Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression.
Lung Injury
GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis.
Lung Injury
Heat shock protein 70 as an indicator of early lung injury caused by exposure to arsenic.
Lung Injury
Heat shock protein 90 inhibitors attenuate LPS-induced endothelial hyperpermeability.
Lung Injury
Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.
Lung Injury
High-altitude pulmonary edema can be prevented by heat shock protein 70-mediated hyperbaric oxygen preconditioning.
Lung Injury
Hsp90 regulation affects the treatment of glucocorticoid for pancreatitis-induced lung injury.
Lung Injury
Post-treatment with a heat shock protein 90 inhibitor prevents chronic lung injury and pulmonary fibrosis, following acute exposure of mice to HCl.
Lung Injury
Postoperative remote lung injury and its impact on surgical outcome.
Lung Injury
Prophylactic inhalation of L-alanyl-L-glutamine enhances heat shock protein 72 and attenuates endotoxin-induced lung injury in rats.
Lung Injury
Protocatechuic acid attenuates lipopolysaccharide-induced septic lung injury in mice: The possible role through suppressing oxidative stress, inflammation and apoptosis.
Lung Injury
Pyrrolidine dithiocarbamate reduces lung reperfusion injury.
Lung Injury
Regulation of iNOS-Derived ROS Generation by HSP90 and Cav-1 in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine Lung Injury.
Lung Injury
Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers.
Lung Injury
Somatostatin Reduces the Acute Lung Injury of Mice via Increasing the Affinity of Glucocorticoid Receptor.
Lung Injury
The HSP90 Inhibitor, AUY-922, Ameliorates the Development of Nitrogen Mustard-Induced Pulmonary Fibrosis and Lung Dysfunction in Mice.
Lung Injury
Thermotolerance induces heat shock protein 72 expression and protects against ischaemia-reperfusion-induced lung injury.
Lung Injury
Treatment with Geranylgeranylacetone Induces Heat Shock Protein 70 and Attenuates Neonatal Hyperoxic Lung Injury in a Model of Bronchopulmonary Dysplasia.
Lung Injury
[Relationship between the expression of heat shock protein 25 and selenium binding protein 1 with ischemia/reperfusion lung injury in vivo: experiment with rats]
Lung Neoplasms
17-AAG Enhances PS-341-Induced Lung Cancer Cell Death by Blocking the NF-?B and PI3K/Akt Pathways.
Lung Neoplasms
17-DMAG-loaded nanofibrous scaffold for effective growth inhibition of lung cancer cells through targeting HSP90 gene expression.
Lung Neoplasms
19P Comparative effectiveness analysis of HSP90 inhibitors in non-small cell lung cancer.
Lung Neoplasms
3-O-(Z)-coumaroyloleanolic acid overcomes Cks1b-induced chemoresistance in lung cancer by inhibiting Hsp90 and MEK pathways.
Lung Neoplasms
A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer.
Lung Neoplasms
A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
Lung Neoplasms
A Randomized, Double-Blinded, Phase II Trial of Carboplatin and Pemetrexed with or without Apatorsen (OGX-427) in Patients with Previously Untreated Stage IV Non-Squamous-Non-Small-Cell Lung Cancer: The SPRUCE Trial.
Lung Neoplasms
Activity of HSP90 Inhibiton in a Metastatic Lung Cancer Patient With a Germline BRCA1 Mutation.
Lung Neoplasms
Activity of IPI-504, a Novel Heat-Shock Protein 90 Inhibitor, in Patients With Molecularly Defined Non-Small-Cell Lung Cancer.
Lung Neoplasms
Activity of the Hsp90 inhibitor luminespib among non-small-cell lung cancers harboring EGFR exon 20 insertions.
Lung Neoplasms
Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells.
Lung Neoplasms
An intronic polymorphism in GRP78 improves chemotherapeutic prediction in non-small-cell lung cancer.
Lung Neoplasms
Anti-tumor selectivity of a novel tubulin and HSP90 dual-targeting inhibitor in non-small cell lung cancer models.
Lung Neoplasms
Antibodies to HSP70 and HSP90 in serum in non-small cell lung cancer patients.
Lung Neoplasms
Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non-Small Cell Lung Cancer Cell Lines and Tumor Models.
Lung Neoplasms
Anticancer activity of methylene blue via inhibition of heat shock protein 70.
Lung Neoplasms
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.
Lung Neoplasms
Aspirin potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer by targeting GRP78 activity.
Lung Neoplasms
Author Correction: Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells.
Lung Neoplasms
Autoantibody to heat shock protein Hsp40 in sera of lung cancer patients.
Lung Neoplasms
AUY922 effectively overcomes MET- and AXL-mediated resistance to EGFR-TKI in lung cancer cells.
Lung Neoplasms
Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform.
Lung Neoplasms
Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device.
Lung Neoplasms
Celastrol induces apoptosis in gefitinib-resistant non-small cell lung cancer cells via caspases-dependent pathways and Hsp90 client protein degradation.
Lung Neoplasms
Celecoxib induces cell death on non-small cell lung cancer cells through endoplasmic reticulum stress.
Lung Neoplasms
Cell death induced by down-regulation of heat shock protein 70 in lung cancer cell lines is p53-independent and does not require DNA cleavage.
Lung Neoplasms
Chalcone-templated Hsp90 inhibitors and their effects on gefitinib resistance in non-small cell lung cancer (NSCLC).
Lung Neoplasms
Chaperonin (HSP60) and annexin-2 are candidate biomarkers for non-small cell lung carcinoma.
Lung Neoplasms
Chaperoning cell death: a critical dual role for Hsp90 in small-cell lung cancer.
Lung Neoplasms
Circulating GRP78 acts as a biomarker in the early diagnosis of lung cancer.
Lung Neoplasms
Circulating heat shock protein 27 as a biomarker for the differentiation of patients with lung cancer and healthy controls--a clinical comparison of different enzyme linked immunosorbent assays.
Lung Neoplasms
Circulating Heat Shock Protein 70 Is a Novel Biomarker for Early Diagnosis of Lung Cancer.
Lung Neoplasms
Clinicopathological and prognostic significance of heat shock protein 27 (HSP27) expression in non-small cell lung cancer: a systematic review and meta-analysis.
Lung Neoplasms
Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells.
Lung Neoplasms
Combined inhibition of Hsp90 and the proteasome affects NSCLC proteostasis and attenuates cell migration.
Lung Neoplasms
Comparison of inhibitory effect of 17-DMAG nanoparticles and free 17-DMAG in HSP90 gene expression in lung cancer.
Lung Neoplasms
Complex Crystal Structure Determination and in vitro Anti-non-small Cell Lung Cancer Activity of Hsp90 N Inhibitor SNX-2112.
Lung Neoplasms
Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.
Lung Neoplasms
Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer.
Lung Neoplasms
Corrigendum to "Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells" [Canc. Lett. 412 (2018) 297-307].
Lung Neoplasms
Corrigendum to"Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo"[Eur. J. Med. Chem. 190 (2020 Mar 15) 112086].
Lung Neoplasms
Deciphering the Inhibition Mechanism of under Trial Hsp90 Inhibitors and Their Analogues: A Comparative Molecular Dynamics Simulation.
Lung Neoplasms
Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas.
Lung Neoplasms
Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols bearing amino acid residues within the 3-amido motif as potent heat shock protein 90 (Hsp90) inhibitors.
Lung Neoplasms
Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response.
Lung Neoplasms
Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors.
Lung Neoplasms
Development of a novel Hsp90 inhibitor NCT-50 as a potential anticancer agent for the treatment of non-small cell lung cancer.
Lung Neoplasms
Differential expression of heat shock protein 90 isoforms in small cell lung cancer.
Lung Neoplasms
Differential mitochondrial proteome analysis of human lung adenocarcinoma and normal bronchial epithelium cell lines using quantitative mass spectrometry.
Lung Neoplasms
Differentially expressed genes associated with human lung cancer.
Lung Neoplasms
Direct targeting of HSP90 with daurisoline destabilizes ?-catenin to suppress lung cancer tumorigenesis.
Lung Neoplasms
Discovery of 2',4'-dimethoxychalcone as a Hsp90 inhibitor and its effect on iressa-resistant non-small cell lung cancer (NSCLC).
Lung Neoplasms
Discovery of hybrid Hsp90 inhibitors and their anti-neoplastic effects against gefitinib-resistant non-small cell lung cancer (NSCLC).
Lung Neoplasms
Discovery of novel HSP90 inhibitors that induced apoptosis and impaired autophagic flux in A549 lung cancer cells.
Lung Neoplasms
Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response.
Lung Neoplasms
Distinct prognostic roles of HSPB1 expression in non-small cell lung cancer.
Lung Neoplasms
Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells.
Lung Neoplasms
Down-regulation of ERK1/2 and AKT-mediated X-ray repair cross-complement group 1 protein (XRCC1) expression by Hsp90 inhibition enhances the gefitinib-induced cytotoxicity in human lung cancer cells.
Lung Neoplasms
Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells.
Lung Neoplasms
Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in human non-small-cell lung cancer cells.
Lung Neoplasms
Down-regulation of MSH2 expression by Hsp90 inhibition enhances cytotoxicity affected by tamoxifen in human lung cancer cells.
Lung Neoplasms
Downregulation of Xeroderma Pigmentosum Complementation Group C Expression by 17-Allylamino-17-Demethoxygeldanamycin Enhances Bevacizumab-Induced Cytotoxicity in Human Lung Cancer Cells.
Lung Neoplasms
Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers.
Lung Neoplasms
Dynamics of Heat Shock Protein 70 Serum Levels As a Predictor of Clinical Response in Non-Small-Cell Lung Cancer and Correlation with the Hypoxia-Related Marker Osteopontin.
Lung Neoplasms
Effect of BIS depletion on HSF1-dependent transcriptional activation in A549 non-small cell lung cancer cells.
Lung Neoplasms
Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor-dependent human lung cancer cells.
Lung Neoplasms
Effects of a Unique Combination of the Whole-Body Low Dose Radiotherapy with Inactivation of Two Immune Checkpoints and/or a Heat Shock Protein on the Transplantable Lung Cancer in Mice.
Lung Neoplasms
Effects of Yiqi Chutan Tang on the Proteome in LEWIS Lung Cancer in Mice.
Lung Neoplasms
Emergence of resistance to tyrosine kinase inhibitors in non-small-cell lung cancer can be delayed by an upfront combination with the HSP90 inhibitor onalespib.
Lung Neoplasms
EML4-ALK fusions: propelling cancer but creating exploitable chaperone dependence.
Lung Neoplasms
Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.
Lung Neoplasms
Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78.
Lung Neoplasms
Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer.
Lung Neoplasms
Enhancement of radiation sensitivity in lung cancer cells by celastrol is mediated by inhibition of Hsp90.
Lung Neoplasms
ER homeostasis and motility of NSCLC cell lines can be therapeutically targeted with combined Hsp90 and HDAC inhibitors.
Lung Neoplasms
ER residential chaperone GRP78 unconventionally relocalizes to the cell surface via endosomal transport.
Lung Neoplasms
ERGIC3 silencing additively enhances the growth inhibition of BFA on lung adenocarcinoma cells.
Lung Neoplasms
Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance.
Lung Neoplasms
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions.
Lung Neoplasms
Expression of heat shock protein 70 and 27 in non-small cell lung cancer and its clinical significance.
Lung Neoplasms
Expression of heat shock protein 70 and p53 in human lung cancer.
Lung Neoplasms
Expression of resistance-related proteins in tumoral and peritumoral tissues of patients with lung cancer.
Lung Neoplasms
Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer.
Lung Neoplasms
Functional promoter rs2868371 variant of HSPB1 associates with radiation-induced esophageal toxicity in patients with non-small-cell lung cancer treated with radio(chemo)therapy.
Lung Neoplasms
GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78.
Lung Neoplasms
Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non-Small Cell Lung Cancer.
Lung Neoplasms
Glucose-related protein (GRP78) and its relationship to the drug-resistance proteins P170, GST-pi, LRP56 and angiogenesis in non-small cell lung carcinomas.
Lung Neoplasms
GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis.
Lung Neoplasms
GRP78 in lung cancer.
Lung Neoplasms
GRP78 up-regulation leads to hypersensitization to cisplatin in A549 lung cancer cells.
Lung Neoplasms
GRP78 upregulation-induced increase in cisplatin sensitivity of SPCA1 lung cancer cells.
Lung Neoplasms
GRP78, intronic polymorphisms, and pharmacogenomics in non-small cell lung cancer.
Lung Neoplasms
Heat shock protein 27 promotes cell proliferation through activator protein-1 in lung cancer.
Lung Neoplasms
Heat Shock Protein 70 (Hsp70) Peptide Activated Natural Killer (NK) Cells for the Treatment of Patients with Non-Small Cell Lung Cancer (NSCLC) after Radiochemotherapy (RCTx) - From Preclinical Studies to a Clinical Phase II Trial.
Lung Neoplasms
Heat shock protein 70 as a predictive marker for platinum-based adjuvant chemotherapy in patients with resected non-small cell lung cancer.
Lung Neoplasms
Heat Shock Protein 90 (Hsp90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivo.
Lung Neoplasms
Heat shock protein 90 inhibition in lung cancer.
Lung Neoplasms
Heat shock protein 90 inhibitors in non-small-cell lung cancer.
Lung Neoplasms
Heat shock protein antagonists in early stage clinical trials for NSCLC.
Lung Neoplasms
Heat shock protein B6 potently increases non-small cell lung cancer growth.
Lung Neoplasms
Heat shock proteins as biomarkers of lung cancer.
Lung Neoplasms
Histone deacetylase, proteasome, and heat shock protein inhibitors for the treatment of lung cancer.
Lung Neoplasms
HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma.
Lung Neoplasms
Hsp60 and Hsp10 down-regulation predicts bronchial epithelial carcinogenesis in smokers with chronic obstructive pulmonary disease.
Lung Neoplasms
HSP90 as a novel molecular target in non-small-cell lung cancer.
Lung Neoplasms
HSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancer.
Lung Neoplasms
HSP90 inhibition induces cytotoxicity via down-regulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells.
Lung Neoplasms
Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR-mutant lung cancer by decreasing client protein expression and angiogenesis.
Lung Neoplasms
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance.
Lung Neoplasms
HSP90 inhibitor (NVP-AUY922) enhances the anti-cancer effect of BCL-2 inhibitor (ABT-737) in small cell lung cancer expressing BCL-2.
Lung Neoplasms
HSP90 inhibitor DPB induces autophagy and more effectively apoptosis in A549 cells combined with autophagy inhibitors.
Lung Neoplasms
Hsp90 Inhibitor Ganetespib Sensitizes Non-Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation.
Lung Neoplasms
Hsp90 inhibitor gedunin causes apoptosis in A549 lung cancer cells by disrupting Hsp90:Beclin-1:Bcl-2 interaction and downregulating autophagy.
Lung Neoplasms
Hsp90 inhibitor NVP-AUY922 enhances the radiation sensitivity of lung cancer cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors.
Lung Neoplasms
HSP90 inhibitor, DMAG, synergizes with radiation of lung cancer cells by interfering with base excision and ATM-mediated DNA repair.
Lung Neoplasms
Hsp90 inhibitors cause G2/M arrest associated with the reduction of Cdc25C and Cdc2 in lung cancer cell lines.
Lung Neoplasms
Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines.
Lung Neoplasms
HSP90 inhibitors in lung cancer: promise still unfulfilled.
Lung Neoplasms
HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line.
Lung Neoplasms
HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer.
Lung Neoplasms
HSPB1 Gene Polymorphisms Predict Risk of Mortality for US Patients After Radio(chemo)therapy for Non-Small Cell Lung Cancer.
Lung Neoplasms
HSPB1 polymorphisms might be associated with radiation-induced damage risk in lung cancer patients treated with radiotherapy.
Lung Neoplasms
Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines.
Lung Neoplasms
Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70.
Lung Neoplasms
Induction of premature senescence by hsp90 inhibition in small cell lung cancer.
Lung Neoplasms
Inhibition of HSP90 molecular chaperones: moving into the clinic.
Lung Neoplasms
Inhibition of thymidine phosphorylase expression by Hsp90 inhibitor potentiates the cytotoxic effect of salinomycin in human non-small-cell lung cancer cells.
Lung Neoplasms
Inhibition of thymidine phosphorylase expression by using an HSP90 inhibitor potentiates the cytotoxic effect of cisplatin in non-small-cell lung cancer cells.
Lung Neoplasms
Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target.
Lung Neoplasms
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
Lung Neoplasms
Involvement of calcium in the differential induction of heat shock protein 70 by heat shock protein 90 inhibitors, geldanamycin and radicicol, in human non-small cell lung cancer H460 cells.
Lung Neoplasms
Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis.
Lung Neoplasms
Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.
Lung Neoplasms
Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis.
Lung Neoplasms
Low-concentration HCP1 inhibits apoptosis in vascular endothelial cells.
Lung Neoplasms
Luminespib plus pemetrexed in patients with non-squamous non-small cell lung cancer.
Lung Neoplasms
Lung cancer: progression of heat shock protein 70 in association with flap endonuclease 1 protein.
Lung Neoplasms
Membrane phospholipids, EML4-ALK, and Hsp90 as novel targets in lung cancer treatment.
Lung Neoplasms
Metastasis and the Tumor Microenvironment: A Joint Metastasis Research Society-AACR Conference - Research on Metastasis: Part 2.
Lung Neoplasms
miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer.
Lung Neoplasms
Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.
Lung Neoplasms
Molecular mechanism and targeted therapy of Hsp90 involved in lung cancer: New discoveries and developments (Review).
Lung Neoplasms
Mortalin overexpression predicts poor prognosis in early stage of non-small cell lung cancer.
Lung Neoplasms
Nck-associated protein 1 associates with HSP90 to drive metastasis in human non-small-cell lung cancer.
Lung Neoplasms
New molecular targeted therapies integrated with radiation therapy in lung cancer.
Lung Neoplasms
Novel Hsp90 Inhibitor C086 Potently Inhibits Non-Small Cell Lung Cancer Cells As A Single Agent Or In Combination With Gefitinib.
Lung Neoplasms
Novel immunohistochemical monoclonal antibody against human glucose-regulated protein 78.
Lung Neoplasms
Nuclear Accumulation of Heat-shock Protein 90 Is Associated with Poor Survival and Metastasis in Patients with Non-small Cell Lung Cancer.
Lung Neoplasms
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
Lung Neoplasms
Organ-specific efficacy of HSP90 inhibitor in multiple-organ metastasis model of chemorefractory small cell lung cancer.
Lung Neoplasms
Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules.
Lung Neoplasms
Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significance.
Lung Neoplasms
Overexpression of heat shock protein 70 inhibits epithelial-mesenchymal transition and cell migration induced by transforming growth factor-? in A549 cells.
Lung Neoplasms
Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients.
Lung Neoplasms
P-glycoprotein confers acquired resistance to 17-DMAG in lung cancers with an ALK rearrangement.
Lung Neoplasms
P-glycoprotein-evading anti-tumor activity of a novel tubulin and HSP90 dual inhibitor in a non-small-cell lung cancer model.
Lung Neoplasms
Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells.
Lung Neoplasms
Phase I/II Study of HSP90 Inhibitor AUY922 and Erlotinib for EGFR-Mutant Lung Cancer With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
Lung Neoplasms
Pifithrin-? is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70.
Lung Neoplasms
Plasma Heat Shock Protein 90 Alpha: A Valuable Predictor of Early Chemotherapy Effectiveness in Advanced Non-Small-Cell Lung Cancer.
Lung Neoplasms
Plasma levels of heat shock protein 90 alpha associated with lung cancer development and treatment responses.
Lung Neoplasms
Presence of heat shock protein 47-positive fibroblasts in cancer stroma is associated with increased risk of postoperative recurrence in patients with lung cancer.
Lung Neoplasms
Prognostic value of the mRNA expression of members of the HSP90 family in non-small cell lung cancer.
Lung Neoplasms
Progression of the role of CRYAB in signaling pathways and cancers.
Lung Neoplasms
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Lung Neoplasms
Quercetin Enhances Chemosensitivity to Gemcitabine in Lung Cancer Cells by Inhibiting Heat Shock Protein 70 Expression.
Lung Neoplasms
Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922.
Lung Neoplasms
Radiosensitization of human lung cancer cells by the novel purine-scaffold Hsp90 inhibitor, PU-H71.
Lung Neoplasms
Randomized Phase III Study of Ganetespib, a Heat Shock Protein 90 Inhibitor, With Docetaxel Versus Docetaxel in Advanced Non-Small-Cell Lung Cancer (GALAXY-2).
Lung Neoplasms
Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells.
Lung Neoplasms
Reversed expression of GRIM-1 and GRP78 in human non-small cell lung cancer.
Lung Neoplasms
Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivo.
Lung Neoplasms
Secreted Heat Shock Protein 90? Attenuated the Effect of Anticancer Drugs in Small-Cell Lung Cancer Cells Through AKT/GSK3?/?-Catenin Signaling.
Lung Neoplasms
Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.
Lung Neoplasms
Sensitization of lung cancer cells by altered dimerization of HSP27.
Lung Neoplasms
Serendipity and technical considerations for the measurement of serum heat shock protein HSP27 in patients with COPD and lung cancer.
Lung Neoplasms
Serum GRP78 as a Tumor Marker and Its Prognostic Significance in Non-Small Cell Lung Cancers: A Retrospective Study.
Lung Neoplasms
Serum heat shock protein 70 levels and lung cancer risk: a case-control study nested in a large cohort study.
Lung Neoplasms
Serum Heat Shock Protein 70, as a Potential Biomarker for Small Cell Lung Cancer.
Lung Neoplasms
Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer.
Lung Neoplasms
Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models.
Lung Neoplasms
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Lung Neoplasms
Targeted Inhibition of the Molecular Chaperone Hsp90 Overcomes ALK Inhibitor Resistance in Non-Small Cell Lung Cancer.
Lung Neoplasms
Targeting heat shock protein 90 overrides the resistance of lung cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1alpha.
Lung Neoplasms
Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer.
Lung Neoplasms
Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells.
Lung Neoplasms
Targeting KRAS-mutant non-small cell lung cancer with the Hsp90 inhibitor ganetespib.
Lung Neoplasms
The analysis of chemotherapy resistance in human lung cancer cell line with microchip-based system.
Lung Neoplasms
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells.
Lung Neoplasms
The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor.
Lung Neoplasms
The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells.
Lung Neoplasms
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.
Lung Neoplasms
The diagnostic value of tumor markers in bronchoalveolar lavage fluid for the peripheral pulmonary carcinoma.
Lung Neoplasms
The heat shock protein 90 inhibitor, AT13387, displays a long duration of action in vitro and in vivo in non-small cell lung cancer.
Lung Neoplasms
The HSP90 inhibitor ganetespib potentiates the antitumor activity of EGFR tyrosine kinase inhibition in mutant and wild-type non-small cell lung cancer.
Lung Neoplasms
The Hsp90 inhibitor IPI-504 rapidly lowers EML4-ALK levels and induces tumor regression in ALK-driven NSCLC models.
Lung Neoplasms
The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth.
Lung Neoplasms
The HSP90 inhibitor, NVP-AUY922, attenuates intrinsic PI3K inhibitor resistance in KRAS-mutant non-small cell lung cancer.
Lung Neoplasms
The HSP90 inhibitor, NVP-AUY922, sensitizes KRAS-mutant non-small cell lung cancer with intrinsic resistance to MEK inhibitor, trametinib.
Lung Neoplasms
The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.
Lung Neoplasms
The relationship between three heat shock protein 70 gene polymorphisms and susceptibility to lung cancer.
Lung Neoplasms
The targeted inhibition of Hsp90 by a synthetic small molecule, DPide offers an effective treatment strategy against TNBCs.
Lung Neoplasms
Treatment of colon and lung cancer patients with ex vivo heat shock protein 70-peptide-activated, autologous natural killer cells: a clinical phase i trial.
Lung Neoplasms
Tumor cell expression of heat shock protein (HSP) 72 is influenced by HSP72 [HSPA1B A(1267)G] polymorphism and predicts survival in small Cell lung cancer (SCLC) patients.
Lung Neoplasms
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.
Lung Neoplasms
Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90-Targeted Therapy.
Lung Neoplasms
Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.
Lung Neoplasms
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
Lung Neoplasms
uc.454 Inhibited Growth by Targeting Heat Shock Protein Family A Member 12B in Non-Small-Cell Lung Cancer.
Lung Neoplasms
Upregulation of GRP78 and GRP94 and its function in chemotherapy resistance to VP-16 in human lung cancer cell line SK-MES-1.
Lung Neoplasms
Vaccination with TCL plus MHSP65 induces anti-lung cancer immunity in mice.
Lung Neoplasms
VDAC upregulation and ?TAT1?mediated ??tubulin acetylation contribute to tanespimycin?induced apoptosis in Calu?1 cells.
Lung Neoplasms
Vorinostat enhances gefitinib?induced cell death through reactive oxygen species?dependent cleavage of HSP90 and its clients in non?small cell lung cancer with the EGFR mutation.
Lung Neoplasms
VP-16 resistance in the NCI-H460 human lung cancer cell line is significantly associated with glucose-regulated protein78 (GRP78) induction.
Lung Neoplasms
[Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung Adenocarcinoma.]
Lung Neoplasms
[Effects of heat shock protein 70-2 gene polymorphisms on the transcription of HSP 70-2 mRNA and the translation of HSP 70 protein in lung cancer].
Lung Neoplasms
[Expression and significance of gp96 and immune-related gene CTLA-4, CD8 in lung cancer tissues]
Lung Neoplasms
[Relationship between chemosensitivity in vitro and the expression of GRP78 in non-small cell lung cancer.]
Lung Neoplasms
[Role of microRNA-155 in Brain Metastasis of Hypoxic Lung Cancer].
Lung Neoplasms
[The correlation between the up-regulation of Hsp90 and drug resistance to cisplatin in lung cancer cell line].
Lung Neoplasms
[The role of GRP78 on the resistance to cisplatin in SPCA-1 cell line]
Lupus Erythematosus, Discoid
[Studies of heat shock protein 60 and heat shock protein 70 in oral lichen planus]
Lupus Erythematosus, Systemic
Autoantibodies to human heat shock protein (hsp)60 may be induced by Escherichia coli groEL.
Lupus Erythematosus, Systemic
Autoantibodies to the heat-shock protein hsp90 in systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Autolytic Mycobacterium leprae Hsp65 fragments may act as biological markers for autoimmune diseases.
Lupus Erythematosus, Systemic
Bioinformatics-Driven New Immune Target Discovery in Disease.
Lupus Erythematosus, Systemic
Detection of antibodies to 65 KD heat shock protein and to human superoxide dismutase in autoimmune hepatitis-molecular mimicry between 65 KD heat shock protein and superoxide dismutase.
Lupus Erythematosus, Systemic
Detection of autoantibodies to the 90 kDa heat shock protein in systemic lupus erythematosus and other autoimmune diseases.
Lupus Erythematosus, Systemic
Determinant spreading: lessons from animal models and human disease.
Lupus Erythematosus, Systemic
Differential heat shock protein overexpression and its clinical relevance in systemic lupus erythematosus.
Lupus Erythematosus, Systemic
DNA Vaccination with Heat Shock Protein 70 Protects (NZB x NZW)F1 Mice from Systemic Lupus Erythematosus.
Lupus Erythematosus, Systemic
Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies to Brn-3 and overexpression of Hsp90.
Lupus Erythematosus, Systemic
Elevated levels of the 70 kD heat shock protein in patients with systemic lupus erythematosus are not dependent on enhanced transcription of the hsp70 gene.
Lupus Erythematosus, Systemic
Elevated levels of the 90 kD heat shock protein in patients with systemic lupus erythematosus are dependent upon enhanced transcription of the hsp90 beta gene.
Lupus Erythematosus, Systemic
Elevated levels of the 90 kDa heat shock protein (hsp90) in SLE correlate with levels of IL-6 and autoantibodies to hsp90.
Lupus Erythematosus, Systemic
Elevation of IL-6 in transgenic mice results in increased levels of the 90 kDa heat shock protein (hsp90) and the production of anti-hsp90 antibodies.
Lupus Erythematosus, Systemic
Enhanced expression of the heat shock protein gene in peripheral blood mononuclear cells of patients with active systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Epitopes of microbial and human heat shock protein 60 and their recognition in myalgic encephalomyelitis.
Lupus Erythematosus, Systemic
Expression of heat-shock proteins in Streptococcus pyogenes and their immunoreactivity with sera from patients with streptococcal diseases.
Lupus Erythematosus, Systemic
Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/lpr mouse model of systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Lupus Erythematosus, Systemic
Heat-shock protein synthesis by human peripheral mononuclear cells from SLE patients.
Lupus Erythematosus, Systemic
Identification of gp96 as a novel target for treatment of autoimmune disease in mice.
Lupus Erythematosus, Systemic
Increased levels of antibodies to heat shock proteins with increasing age in Mrl/Mp-lpr/lpr mice.
Lupus Erythematosus, Systemic
Interleukin 6 activates heat-shock protein 90 beta gene expression.
Lupus Erythematosus, Systemic
Lupus-specific kidney deposits of HSP90 are associated with altered IgG idiotypic interactions of anti-HSP90 autoantibodies.
Lupus Erythematosus, Systemic
Polymorphism of the heat-shock protein gene HSP70-2 in systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Role of hsp90 in systemic lupus erythematosus and its clinical relevance.
Lupus Erythematosus, Systemic
Spontaneous activation of heat shock protein gene transcription in peripheral blood mononuclear cells of individuals with active systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Surface expression of heat shock protein 90 by blood mononuclear cells from patients with systemic lupus erythematosus.
Lupus Erythematosus, Systemic
The 8.5-kb PstI allele of the stress protein gene, Hsp70-2: an independent risk factor for systemic lupus erythematosus in African Americans?
Lupus Erythematosus, Systemic
The expression of molecular chaperone HSP90 and IL-6 in patients with systemic lupus erythematosus.
Lupus Erythematosus, Systemic
The HSP90 Inhibitor Ganetespib Alleviates Disease Progression and Augments Intermittent Cyclophosphamide Therapy in the MRL/lpr Mouse Model of Systemic Lupus Erythematosus.
Lupus Erythematosus, Systemic
The HSP90 Inhibitor, 17-AAG, Influences the Activation and Proliferation of T Lymphocytes via AKT/GSK3? Signaling in MRL/lpr Mice.
Lupus Erythematosus, Systemic
The regulation of heat shock proteins and their role in systemic lupus erythematosus.
Lupus Erythematosus, Systemic
The role of hsp90 in SLE.
Lupus Erythematosus, Systemic
The tissue specific elevation in synthesis of the 90 kDa heat shock protein precedes the onset of disease in lupus prone MRL/lpr mice.
Lupus Erythematosus, Systemic
Transcription of the genes encoding the small heat shock protein ubiquitin is unchanged in patients with systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Transposable element dysregulation in systemic lupus erythematosus and regulation by histone conformation and Hsp90.
Lupus Erythematosus, Systemic
[The relationship between mRNA level of glucocorticoid receptor ?, heat shock protein 90, protein level of macrophage migration inhibitory factor and glucocorticoid resistance in systemic lupus erythematosus].
Lupus Nephritis
Lupus-specific kidney deposits of HSP90 are associated with altered IgG idiotypic interactions of anti-HSP90 autoantibodies.
Lyme Disease
Characterization of Borrelia burgdorferi proteins reactive with antibodies in synovial fluid of a patient with Lyme arthritis.
Lyme Disease
Evaluation of genetic divergence among Borrelia burgdorferi isolates by use of OspA, fla, HSP60, and HSP70 gene probes.
Lyme Disease
groEL expression in gyrB mutants of Borrelia burgdorferi.
Lyme Disease
H9724, a monoclonal antibody to Borrelia burgdorferi's flagellin, binds to heat shock protein 60 (HSP60) within live neuroblastoma cells: a potential role for HSP60 in peptide hormone signaling and in an autoimmune pathogenesis of the neuropathy of Lyme disease.
Lyme Disease
Heat shock protein 70 of the agent of human granulocytic ehrlichiosis binds to Borrelia burgdorferi antibodies.
Lyme Disease
Immune recognition of human Hsp60 by Lyme disease patient sera.
Lyme Disease
T cell and antibody reactivity with the Borrelia burgdorferi 60-kDa heat shock protein in Lyme arthritis.
Lyme Disease
Utility of laboratory testing in autoimmune inner ear disease.
Lymphatic Metastasis
Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules.
Lymphatic Metastasis
Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer.
Lymphatic Metastasis
Can breast cancer Hsp 27 (Heat Shock Protein 27000) expression influence axillary lymph node status?
Lymphatic Metastasis
Concomitant high expression of ER?36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior.
Lymphatic Metastasis
Construction and selection of subtracted cDNA library of mouse hepatocarcinoma cell lines with different lymphatic metastasis potential.
Lymphatic Metastasis
Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan.
Lymphatic Metastasis
Elevated HSP90 associates with expression of HIF-1? and p-AKT and is predictive of poor prognosis in nasopharyngeal carcinoma.
Lymphatic Metastasis
Estrogen receptor-?36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
Lymphatic Metastasis
Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer.
Lymphatic Metastasis
Expression of major heat shock proteins in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy.
Lymphatic Metastasis
Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer.
Lymphatic Metastasis
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.
Lymphatic Metastasis
GRP78 and GAL3, differentially regulated by lymph node homogenates, as potential biomarkers for lymph node metastasis in mouse hepatocellular carcinoma cells.
Lymphatic Metastasis
GRP78 positively regulates estrogen?stimulated cell growth mediated by ER??36 in gastric cancer cells.
Lymphatic Metastasis
Heat shock protein 27 overexpression in breast cancer lymph node metastasis.
Lymphatic Metastasis
Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer.
Lymphatic Metastasis
Heat shock protein 90 as a molecular target for therapy in oral squamous cell carcinoma: Inhibitory effects of 17?DMAG and ganetespib on tumor cells.
Lymphatic Metastasis
High expression of glucose-regulated protein 78 (GRP78) is associated with metastasis and poor prognosis in patients with esophageal squamous cell carcinoma.
Lymphatic Metastasis
High expression of heat shock protein 90 is associated with tumor aggressiveness and poor prognosis in patients with advanced gastric cancer.
Lymphatic Metastasis
High Levels of Hsp90 Cochaperone p23 Promote Tumor Progression and Poor Prognosis in Breast Cancer by Increasing Lymph Node Metastases and Drug Resistance.
Lymphatic Metastasis
Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry.
Lymphatic Metastasis
Immunohistochemical expression of Hsp60 correlates with tumor progression and hormone resistance in prostate cancer.
Lymphatic Metastasis
Is co-expression of USP22 and HSP90 more effective in predicting prognosis of gastric cancer?
Lymphatic Metastasis
MDA-9 and GRP78 as potential diagnostic biomarkers for early detection of melanoma metastasis.
Lymphatic Metastasis
Mortalin expression in pancreatic cancer and its clinical and prognostic significance.
Lymphatic Metastasis
Mortalin overexpression predicts poor prognosis in early stage of non-small cell lung cancer.
Lymphatic Metastasis
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
Lymphatic Metastasis
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Lymphatic Metastasis
Preoperative heat shock protein 47 levels identify colorectal cancer patients with lymph node metastasis and poor prognosis.
Lymphatic Metastasis
Proteomics analysis of differential protein expression identifies heat shock protein 47 as a predictive marker for lymph node metastasis in patients with colorectal cancer.
Lymphatic Metastasis
Relationship between the expression of phosphorylated heat shock protein beta-1 with lymph node metastases of breast cancer.
Lymphatic Metastasis
Significance of expression of heat shock protein90alpha in human gastric cancer.
Lymphatic Metastasis
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast.
Lymphatic Metastasis
The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase.
Lymphatic Metastasis
[Comparative proteomics of the serum in patients with nasopharyngeal carcinoma: a study with two-dimensional electrophoresis and MALDI-TOF-MS]
Lymphatic Metastasis
[Expression of HSP27 in colorectal carcinoma and its relationship with lymphatic metastasis.]
Lymphocytic Choriomeningitis
Immunization with a lymphocytic choriomeningitis virus peptide mixed with heat shock protein 70 results in protective antiviral immunity and specific cytotoxic T lymphocytes.
Lymphoma
16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells.
Lymphoma
17-AAG enhances the cytotoxicity of flavopiridol in mantle cell lymphoma via autophagy suppression.
Lymphoma
A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas.
Lymphoma
A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-?B.
Lymphoma
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.
Lymphoma
Aberrant protein expression in cerebral cortex of fetus with Down syndrome.
Lymphoma
Abundance of heat shock proteins (hsp89, hsp60, and hsp27) in malignant cells of Hodgkin's disease.
Lymphoma
Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma.
Lymphoma
Amino acid sequence of a chicken heat shock protein derived from the complementary DNA nucleotide sequence.
Lymphoma
Analysis of native forms and isoform compositions of the mouse 90-kDa heat shock protein, HSP90.
Lymphoma
Anti-cancer activity of withaferin A in B-cell lymphoma.
Lymphoma
Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma.
Lymphoma
Apoptotic induction and inhibition of NF-?B signaling pathway in human prostatic cancer PC3 cells by natural compound 2,2'-oxybis (4-allyl-1-methoxybenzene), biseugenol B, from Litsea costalis: an in vitro study.
Lymphoma
Assessing and comparing antioxidant activities of lactobacilli strains by using different chemical and cellular antioxidant methods.
Lymphoma
BIIB021, an Hsp90 inhibitor: A promising therapeutic strategy for blood malignancies (Review).
Lymphoma
Calmodulin-regulated binding of the 90-kDa heat shock protein to actin filaments.
Lymphoma
CD30 Induces Heat Shock Protein 90 and Signal Integration in Classic Hodgkin Lymphoma Cells.
Lymphoma
CHM-1 Suppresses Formation of Cell Surface-associated GRP78-p85? Complexes, Inhibiting PI3K-AKT Signaling and Inducing Apoptosis of Human Nasopharyngeal Carcinoma Cells.
Lymphoma
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3?-dependent inhibition of apoptosis and ER stress.
Lymphoma
Clinical experience with the heat shock protein-90 inhibitor, tanespimycin, in patients with relapsed lymphoma.
Lymphoma
Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: A highly active combination against human mantle cell lymphoma (MCL) cells.
Lymphoma
Consequences of heat shock protein 72 (Hsp72) expression and activity on stress-induced apoptosis in CD30(+) NPM-ALK(+) anaplastic large-cell lymphomas.
Lymphoma
Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9.
Lymphoma
Dopamine impairs functional integrity of rat hepatocytes through nuclear factor kappa B activity modulation: An in vivo, ex vivo, and in vitro study.
Lymphoma
Dual Targeting of Protein Degradation Pathways with the Selective HDAC6 Inhibitor ACY-1215 and Bortezomib Is Synergistic in Lymphoma.
Lymphoma
Effect of alterations in apoptotic pathway on development of metabolic syndrome in patients with psoriasis vulgaris.
Lymphoma
Effect of high cell density on the growth properties of tumor cells: a role in tumor cytotoxicity of chemotherapeutic drugs.
Lymphoma
Evidence for intracellular association of the glucocorticoid receptor with the 90-kDa heat shock protein.
Lymphoma
Exogenous vascular endothelial growth factor delivery prior to endothelial precursor cell transplantation in orthotopic liver transplantation-induced hepatic ischemia/reperfusion injury.
Lymphoma
Expression of a defective mouse mammary tumor virus envelope glycoprotein precursor which binds stably to GRP78 within the lumen of the endoplasmic reticulum is associated with decreased glucocorticoid-induced apoptosis in mouse lymphoma cells.
Lymphoma
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma
Expression of HSP60 in gastric lymphoma treated by a combination of trichosanthin and radiotherapy and its mechanism.
Lymphoma
FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy.
Lymphoma
Ganetespib: research and clinical development.
Lymphoma
Heat shock protein 70 (Hsp70)-stimulated deoxycytidine deaminases from a human lymphoma cell but not the activation-induced cytidine deaminase (AID) from Ramos 6.4 human Burkitt's lymphoma cells.
Lymphoma
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.
Lymphoma
Heat shock protein 90 inhibitors in non-small-cell lung cancer.
Lymphoma
Heat shock protein 90 inhibitors repress latent membrane protein 1 (LMP1) expression and proliferation of Epstein-Barr virus-positive natural killer cell lymphoma.
Lymphoma
Heat shock protein 90 relieves heat stress damage of myocardial cells by regulating Akt and PKM2 signaling in vivo.
Lymphoma
Heat shock protein 90.
Lymphoma
Heat shock protein vaccination and directed IL-2 therapy amplify tumor immunity rapidly following bone marrow transplantation in mice.
Lymphoma
Hexavalent chromium-induced apoptosis in Hep3B cells is accompanied by calcium overload, mitochondrial damage, and AIF translocation.
Lymphoma
HSP100, a 100-kDa heat shock protein, is a Ca2+-calmodulin-regulated actin-binding protein.
Lymphoma
Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR-mutant lung cancer by decreasing client protein expression and angiogenesis.
Lymphoma
HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma.
Lymphoma
HSP90 Inhibitor 17-AAG Selectively Eradicates Lymphoma Stem Cells.
Lymphoma
Hsp90? Mediates BMI1 Expression in Breast Cancer Stem/Progenitor Cells through Facilitating Nuclear Translocation of c-Myc and EZH2.
Lymphoma
HSPH1 inhibition downregulates Bcl-6 and c-Myc and hampers the growth of human aggressive B-cell non-Hodgkin lymphoma.
Lymphoma
Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry.
Lymphoma
Improved Clinical Outcome in Indolent B-Cell Lymphoma Patients Vaccinated with Autologous Tumor Cells Experiencing Immunogenic Death.
Lymphoma
Increased Tenascin C, Osteopontin and HSP90 Levels in Plasmatic Small Extracellular Vesicles of Pediatric ALK-Positive Anaplastic Large Cell Lymphoma: New Prognostic Biomarkers?
Lymphoma
Induction of endoplasmic reticulum stress in thymic lymphocytes by the envelope precursor polyprotein of a murine leukemia virus during the preleukemic period.
Lymphoma
Induction of human hsp60 expression in monocytic cell lines.
Lymphoma
Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors.
Lymphoma
Involvement of c-Fos in signaling grp78 induction following ER calcium release.
Lymphoma
KSHV vFLIP binds to IKK-gamma to activate IKK.
Lymphoma
Lee J, Zhang LL, Wu W, et al. Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma. Blood Adv. 2018;2(16):2039-2051.
Lymphoma
Localization of collagen modifying enzymes on fibroblastic reticular cells and follicular dendritic cells in non-neoplastic and neoplastic lymphoid tissues.
Lymphoma
Matrix metalloproteinase-9 is upregulated in nucleophosmin-anaplastic lymphoma kinase-positive anaplastic lymphomas and activated at the cell surface by the chaperone heat shock protein 90 to promote cell invasion.
Lymphoma
Modulatory effects of mycobacterial heat-shock protein 70 in DNA vaccination against lymphoma.
Lymphoma
Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin.
Lymphoma
Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy.
Lymphoma
P-glycoprotein confers acquired resistance to 17-DMAG in lung cancers with an ALK rearrangement.
Lymphoma
Polymorphism in the tumor necrosis factor-alpha promotor region and in the heat shock protein 70 genes associated with malignant tumors.
Lymphoma
Preferential synthesis of the 78-Kd glucose-regulated protein in glucocorticoid-treated S49 mouse lymphoma cells.
Lymphoma
Proteome-wide changes induced by the Hsp90 inhibitor, geldanamycin in anaplastic large cell lymphoma cells.
Lymphoma
Proteomic analysis of exosomes derived from human lymphoma cells.
Lymphoma
Purification and characterization of the 90-kDa heat-shock protein from mammalian tissues.
Lymphoma
Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71.
Lymphoma
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.
Lymphoma
Relationship between defective mouse mammary tumor virus envelope glycoprotein synthesis and GRP78 synthesis in glucocorticoid-treated mouse lymphoma cells. Evidence for translational control of GRP78 synthesis.
Lymphoma
Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.
Lymphoma
Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.
Lymphoma
Targeted therapy of BCL6-dependent diffuse large B-cell lymphomas by heat-shock protein 90 inhibition.
Lymphoma
The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells.
Lymphoma
The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9.
Lymphoma
The heat shock protein 90 inhibitor BIIB021 suppresses the growth of T and natural killer cell lymphomas.
Lymphoma
The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.
Lymphoma
The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation.
Lymphoma
The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression.
Lymphoma
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78.
Lymphoma
The Hsp90 inhibitor IPI-504 rapidly lowers EML4-ALK levels and induces tumor regression in ALK-driven NSCLC models.
Lymphoma
The Hsp90 inhibitor SNX-7081 is synergistic with fludarabine nucleoside via DNA damage and repair mechanisms in human, p53-negative chronic lymphocytic leukemia.
Lymphoma
Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.
Lymphoma
Thermotolerance in the absence of induced heat shock proteins in a murine lymphoma.
Lymphoma
Three-step purification method and characterization of the bovine brain 90-kDa heat shock protein.
Lymphoma
Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins.
Lymphoma
Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein.
Lymphoma
Zinc carnosine works with bovine colostrum in truncating heavy exercise-induced increase in gut permeability in healthy volunteers.
Lymphoma, B-Cell
16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells.
Lymphoma, B-Cell
A novel strategy for preserving renal grafts in an ex vivo setting: potential for enhancing the marginal donor pool.
Lymphoma, B-Cell
A study on the biological function of heat shock factor 1 proteins in breast cancer.
Lymphoma, B-Cell
Are Atlantic cod in Store Lungegårdsvann, a seawater recipient in Bergen, affected by environmental contaminants? A qRT-PCR survey.
Lymphoma, B-Cell
AUY922 effectively targets against activated B cell subtype of diffuse large B-cell lymphoma and low-grade lymphoma cells harboring genetic alteration-associated nuclear factor-?B activation.
Lymphoma, B-Cell
CHM-1 Suppresses Formation of Cell Surface-associated GRP78-p85? Complexes, Inhibiting PI3K-AKT Signaling and Inducing Apoptosis of Human Nasopharyngeal Carcinoma Cells.
Lymphoma, B-Cell
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3?-dependent inhibition of apoptosis and ER stress.
Lymphoma, B-Cell
Co-expression network analysis of Down's syndrome based on microarray data.
Lymphoma, B-Cell
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.
Lymphoma, B-Cell
Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9.
Lymphoma, B-Cell
Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways.
Lymphoma, B-Cell
Dendritic cells in neointima formation after rat carotid balloon injury: coordinated expression withanti-apoptotic Bcl-2 and HSP47 in arterial repair.
Lymphoma, B-Cell
Dietary supplementation with essential amino acids boosts the beneficial effects of rosuvastatin on mouse kidney.
Lymphoma, B-Cell
Dopamine impairs functional integrity of rat hepatocytes through nuclear factor kappa B activity modulation: An in vivo, ex vivo, and in vitro study.
Lymphoma, B-Cell
Effect of a heat shock protein 90-specific inhibitor on the proliferation and apoptosis induced by VEGF-C in cervical cancer cells.
Lymphoma, B-Cell
Effect of dimerized thrombin fragment TP508 on acute myocardial ischemia reperfusion injury in hypercholesterolemic swine.
Lymphoma, B-Cell
Effect of Hydrogen Sulfide in a Porcine Model of Myocardial Ischemia-Reperfusion: Comparison of Different Administration Regimens and Characterization of the Cellular Mechanisms of Protection.
Lymphoma, B-Cell
Effects of 17-DMAG on diffuse large B-cell lymphoma cell apoptosis.
Lymphoma, B-Cell
Effects of microRNA-21 and microRNA-24 inhibitors on neuronal apoptosis in ischemic stroke.
Lymphoma, B-Cell
Exogenous vascular endothelial growth factor delivery prior to endothelial precursor cell transplantation in orthotopic liver transplantation-induced hepatic ischemia/reperfusion injury.
Lymphoma, B-Cell
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, B-Cell
Ganetespib: research and clinical development.
Lymphoma, B-Cell
Heat shock protein 90 inhibitors in non-small-cell lung cancer.
Lymphoma, B-Cell
Hexavalent chromium-induced apoptosis in Hep3B cells is accompanied by calcium overload, mitochondrial damage, and AIF translocation.
Lymphoma, B-Cell
Identification and characterization of BCL6 translocation partner genes in primary gastric high-grade B-cell lymphoma: heat shock protein 89 alpha is a novel fusion partner gene of BCL6.
Lymphoma, B-Cell
In vitro long-term culture of isolated ovine preantral follicles: Influence of ethanol on steroid production, oocyte meiotic resumption, and metabolomic profile.
Lymphoma, B-Cell
Lithium beyond psychiatric indications: the reincarnation of a new old drug.
Lymphoma, B-Cell
Magnetic thermoablation stimuli alter BCL2 and FGF-R1 but not HSP70 expression profiles in BT474 breast tumors.
Lymphoma, B-Cell
Mangiferin mitigates di-(2-ethylhexyl) phthalate-induced testicular injury in rats by modulating oxidative stress-mediated signals, inflammatory cascades, apoptotic pathways, and steroidogenesis.
Lymphoma, B-Cell
Methane supplementation improves graft function in experimental heart transplantation.
Lymphoma, B-Cell
Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.
Lymphoma, B-Cell
Neuroprotective effects of selegiline on rat neural stem cells treated with hydrogen peroxide.
Lymphoma, B-Cell
Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas.
Lymphoma, B-Cell
Overexpression of ER Protein Processing and Apoptosis Regulator Genes in Human Embryonic Kidney 293 Cells Improves Gene Therapy Vectors Production.
Lymphoma, B-Cell
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage.
Lymphoma, B-Cell
PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure.
Lymphoma, B-Cell
Promising therapies for the treatment of chronic lymphocytic leukemia.
Lymphoma, B-Cell
Protective effect of eupatilin against renal ischemia-reperfusion injury in mice.
Lymphoma, B-Cell
Protective Effect of Eupatilin Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice.
Lymphoma, B-Cell
Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.
Lymphoma, B-Cell
Rutin hydrate inhibits apoptosis in the brains of cadmium chloride-treated rats via preserving the mitochondrial integrity and inhibiting endoplasmic reticulum stress.
Lymphoma, B-Cell
Specific peptides for the therapeutic targeting of oncogenes.
Lymphoma, B-Cell
Survivin Signaling in Clinical Oncology: A Multifaceted Dragon.
Lymphoma, B-Cell
Targeted therapy of BCL6-dependent diffuse large B-cell lymphomas by heat-shock protein 90 inhibition.
Lymphoma, B-Cell
The heat shock protein 90 inhibitor IPI-504 induces apoptosis of AKT-dependent diffuse large B-cell lymphomas.
Lymphoma, B-Cell
Thermotolerance in the absence of induced heat shock proteins in a murine lymphoma.
Lymphoma, B-Cell
Wilms' tumor 1-associating protein plays an aggressive role in diffuse large B-cell lymphoma and forms a complex with BCL6 via Hsp90.
Lymphoma, B-Cell
Zinc carnosine works with bovine colostrum in truncating heavy exercise-induced increase in gut permeability in healthy volunteers.
Lymphoma, B-Cell, Marginal Zone
Antibodies to human gastric epithelial cells and heat shock protein 60 in Helicobacter pylori positive mucosa associated lymphoid tissue lymphoma.
Lymphoma, B-Cell, Marginal Zone
Detection of Helicobacter pylori associated antigen and heat shock protein 60 on follicular dendritic cells in the germinal centres of low grade B cell lymphoma of gastric mucosa associated lymphoid tissue (MALT).
Lymphoma, B-Cell, Marginal Zone
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, B-Cell, Marginal Zone
Helicobacter pylori heat shock protein B (HspB) localizes in vivo in the gastric mucosa and MALT lymphoma.
Lymphoma, B-Cell, Marginal Zone
Immune response in Helicobacter pylori-induced low-grade gastric-mucosa-associated lymphoid tissue (MALT) lymphoma.
Lymphoma, B-Cell, Marginal Zone
Immunoglobulin G1 antibody response to Helicobacter pylori heat shock protein 60 is closely associated with low-grade gastric mucosa-associated lymphoid tissue lymphoma.
Lymphoma, B-Cell, Marginal Zone
Serum antibodies to Helicobacter pylori and its heat-shock protein 60 correlate with the response of gastric mucosa-associated lymphoid tissue lymphoma to eradication of H. pylori.
Lymphoma, B-Cell, Marginal Zone
[Gastric mucosal immunity induced by H. pylori infection]
Lymphoma, Follicular
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, Large B-Cell, Diffuse
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, Large B-Cell, Diffuse
Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas.
Lymphoma, Large B-Cell, Diffuse
Regulation of hsc70 expression in the human histiocytic lymphoma cell line, U937.
Lymphoma, Large B-Cell, Diffuse
Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.
Lymphoma, Large B-Cell, Diffuse
Wilms' tumor 1-associating protein plays an aggressive role in diffuse large B-cell lymphoma and forms a complex with BCL6 via Hsp90.
Lymphoma, Large-Cell, Anaplastic
Abundance of heat shock proteins (hsp89, hsp60, and hsp27) in malignant cells of Hodgkin's disease.
Lymphoma, Large-Cell, Anaplastic
CD30 Induces Heat Shock Protein 90 and Signal Integration in Classic Hodgkin Lymphoma Cells.
Lymphoma, Large-Cell, Anaplastic
Consequences of heat shock protein 72 (Hsp72) expression and activity on stress-induced apoptosis in CD30(+) NPM-ALK(+) anaplastic large-cell lymphomas.
Lymphoma, Large-Cell, Anaplastic
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, Large-Cell, Anaplastic
FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy.
Lymphoma, Large-Cell, Anaplastic
Increased Tenascin C, Osteopontin and HSP90 Levels in Plasmatic Small Extracellular Vesicles of Pediatric ALK-Positive Anaplastic Large Cell Lymphoma: New Prognostic Biomarkers?
Lymphoma, Large-Cell, Anaplastic
Proteome-wide changes induced by the Hsp90 inhibitor, geldanamycin in anaplastic large cell lymphoma cells.
Lymphoma, Large-Cell, Anaplastic
The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein.
Lymphoma, Large-Cell, Anaplastic
The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression.
Lymphoma, Mantle-Cell
17-AAG enhances the cytotoxicity of flavopiridol in mantle cell lymphoma via autophagy suppression.
Lymphoma, Mantle-Cell
Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma.
Lymphoma, Mantle-Cell
Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma.
Lymphoma, Mantle-Cell
Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: A highly active combination against human mantle cell lymphoma (MCL) cells.
Lymphoma, Mantle-Cell
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, Mantle-Cell
HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma.
Lymphoma, Mantle-Cell
Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors.
Lymphoma, Mantle-Cell
Lee J, Zhang LL, Wu W, et al. Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma. Blood Adv. 2018;2(16):2039-2051.
Lymphoma, Mantle-Cell
Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.
Lymphoma, Mantle-Cell
The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9.
Lymphoma, Mantle-Cell
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78.
Lymphoma, Non-Hodgkin
AUY922 effectively targets against activated B cell subtype of diffuse large B-cell lymphoma and low-grade lymphoma cells harboring genetic alteration-associated nuclear factor-?B activation.
Lymphoma, Non-Hodgkin
Experience with HSP90 inhibitor AUY922 in patients with relapsed or refractory non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, Non-Hodgkin
Increasing Levels of Serum Heat Shock Protein 70 Precede the Development of AIDS-Defining Non-Hodgkin Lymphoma Among Carriers of HLA-B8-DR3.
Lymphoma, Non-Hodgkin
Polymorphism in the tumor necrosis factor-alpha promotor region and in the heat shock protein 70 genes associated with malignant tumors.
Lymphoma, Non-Hodgkin
Targeted therapy of BCL6-dependent diffuse large B-cell lymphomas by heat-shock protein 90 inhibition.
Lymphoma, Primary Effusion
A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-?B.
Lymphoma, Primary Effusion
KSHV vFLIP binds to IKK-gamma to activate IKK.
Lymphoma, Primary Effusion
The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells.
Lymphoma, T-Cell
Correlation of BAG-3 and heat shock protein 70 with CD30 expression in T-cell lymphomas.
Lymphoma, T-Cell
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphoma, T-Cell
Thermotolerance in the absence of induced heat shock proteins in a murine lymphoma.
Lymphoma, T-Cell, Cutaneous
Vorinostat interferes with the signaling transduction pathway of T-cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T-cell lymphoma.
Lymphoma, T-Cell, Peripheral
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Lymphopenia
Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling.
Lymphopenia
Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans.
Lymphopenia
Epidemiology, genetic variants and clinical course of natural infections with Anaplasma phagocytophilum in a dairy cattle herd.
Lymphoproliferative Disorders
Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia.
Lysosomal Storage Diseases
Intermittent enzyme replacement therapy prevents Neu1 deficiency.
Machado-Joseph Disease
HSP27 and cell death in spinocerebellar ataxia type 3.
Machado-Joseph Disease
Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases.
Machado-Joseph Disease
Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3.
Macular Degeneration
?B-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition.
Macular Degeneration
Cigarette smoke-related hydroquinone induces filamentous actin reorganization and heat shock protein 27 phosphorylation through p38 and extracellular signal-regulated kinase 1/2 in retinal pigment epithelium: implications for age-related macular degeneration.
Macular Degeneration
Detection of heat shock protein 70 in choroidal neovascularisation secondary to age related macular degeneration.
Macular Degeneration
Hsp90 as a Potential Therapeutic Target in Retinal Disease.
Macular Degeneration
Regulated heat shock protein 27 expression in human retinal pigment epithelium.
Macular Degeneration
The Molecular Chaperone GRP78/BiP as a Therapeutic Target for Neurodegenerative Disorders: A Mini Review.
Macular Degeneration
Unravelling the Role of HSP70 as the Unexplored Molecular Target in Age-Related Macular Degeneration.
Macular Edema
Glucose-regulated protein 78 in the aqueous humor in diabetic macular edema patients.
Malaria
Actin-binding proteins of invasive malaria parasites and the regulation of actin polymerization by a complex of 32/34-kDa proteins associated with heat shock protein 70kDa.
Malaria
Antibodies specific for heat shock proteins in human and murine malaria.
Malaria
Biochemical characterization of the apicoplast-targeted AAA+ ATPase ClpB from Plasmodium falciparum.
Malaria
Cellular and antibody responses to the Plasmodium falciparum heat shock protein Pf72/HSP70 during and after acute malaria in individuals from an endemic area of Brazil.
Malaria
Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients.
Malaria
Characterization of Plasmodium vivax heat shock protein 70 and evaluation of its value for serodiagnosis of tertian malaria.
Malaria
Co-chaperones of Hsp90 in Plasmodium falciparum and their concerted roles in cellular regulation.
Malaria
Comparative structure-function features of Hsp70s of Plasmodium falciparum and human origins.
Malaria
Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites.
Malaria
Detection of malaria infection via latex agglutination assay.
Malaria
Heat shock protein 90 as a drug target against protozoan infections: Biochemical characterization of Hsp90 from Plasmodium falciparum, Trypanosoma evansi and evaluation of its inhibitor as a candidate drug.
Malaria
Heat shock protein 90 from neglected protozoan parasites.
Malaria
Hsp70s and J Proteins of Plasmodium Parasites Infecting Rodents and Primates: Structure, Function, Clinical Relevance, and Drug Targets.
Malaria
Human response to a malaria vaccine candidate antigen.
Malaria
Humoral and cellular immune responses to glucose regulated protein 78 -- a novel Leishmania donovani antigen.
Malaria
Humoral immune response to the 72 kDa heat shock protein from Plasmodium falciparum in populations at hypoendemic areas of malaria in western Brazilian Amazon.
Malaria
Identification and characterization of the antiplasmodial activity of Hsp90 inhibitors.
Malaria
Immunization with the malaria heat shock like protein hsp70-1 enhances transmission to the mosquito.
Malaria
Metalloprotease activity in a small heat shock protein of the human malaria parasite Plasmodium vivax.
Malaria
Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum.
Malaria
Molecular analysis of Plasmodium falciparum co-chaperone Aha1 supports its interaction with and regulation of Hsp90 in the malaria parasite.
Malaria
Molecular characterization of the heat shock protein 90 gene of the human malaria parasite Plasmodium falciparum.
Malaria
Molecular cloning and antigenic mapping of heat-shock protein 70 from the malaria species Plasmodium bergheI.
Malaria
Mouse studies on inhibitors of Plasmodium falciparum Hsp90: progress and challenges.
Malaria
Overproduction, purification, and characterization of the Plasmodium falciparum heat shock protein 70.
Malaria
Partners in Mischief: Functional Networks of Heat Shock Proteins of Plasmodium falciparum and Their Influence on Parasite Virulence.
Malaria
Placental Malaria: A New Insight into the Pathophysiology.
Malaria
Plasmodial heat shock proteins: targets for chemotherapy.
Malaria
Plasmodial HSP70s are functionally adapted to the malaria parasite life cycle.
Malaria
Plasmodium falciparum heat shock protein 70 is able to suppress the thermosensitivity of an Escherichia coli DnaK mutant strain.
Malaria
Plasmodium falciparum Hop: detailed analysis on complex formation with Hsp70 and Hsp90.
Malaria
Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion.
Malaria
Plasmodium falciparum R2TP complex: driver of parasite Hsp90 function.
Malaria
Plasmodium falciparum signal peptide peptidase cleaves malaria heat shock protein 101 (HSP101). Implications for gametocytogenesis.
Malaria
Post-transcriptional repair of a split heat shock protein 90 gene by mRNA trans-splicing.
Malaria
Precise limitation of concerted evolution to ORFs in mosquito Hsp82 genes.
Malaria
Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites.
Malaria
PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes.
Malaria
Repurposing drugs to target the malaria parasite unfolding protein response.
Malaria
Selective modulation of plasmodial Hsp70s by small molecules with antimalarial activity.
Malaria
Solution structure of Plasmodium falciparum Hsp90 indicates a high flexible dimer.
Malaria
Stage-specific expression of heat shock protein 90 in murine malaria parasite Plasmodium yoelii.
Malaria
Strong renal expression of heat shock protein 70, high mobility group box 1, inducible nitric oxide synthase, and nitrotyrosine in mice model of severe malaria.
Malaria
Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif.
Malaria
Structural insights into the binding mechanism of Plasmodium falciparum exported Hsp40-Hsp70 chaperone pair.
Malaria
Structure of the ATP-binding domain of Plasmodium falciparum Hsp90.
Malaria
Targeting Heat Shock Protein 90 for Malaria.
Malaria
The endoplasmic reticulum chaperone PfGRP170 is essential for asexual development and is linked to stress response in malaria parasites.
Malaria
The heat shock protein 40 family of the malaria parasite Plasmodium falciparum.
Malaria
The heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycin.
Malaria
The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host-parasite interface.
Malaria
Three-dimensional structure of heat shock protein 90 from Plasmodium falciparum: molecular modelling approach to rational drug design against malaria.
Malaria
Uncoupling the Threading and Unfoldase Actions of Plasmodium HSP101 Reveals Differences in Export between Soluble and Insoluble Proteins.
Malaria, Falciparum
Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites.
Malnutrition
Heat shock proteins in porcine ovary: synthesis, accumulation and regulation by stress and hormones.
Malocclusion
MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Marek Disease
Heat-shock protein 70 is associated with the entry of Marek's disease virus into fibroblast.
Marek Disease
Interaction of Marek's disease virus oncoprotein Meq with heat-shock protein 70 in lymphoid tumour cells.
Mastitis
Differentiation of non-aureus staphylococci species isolated from bovine mastitis by PCR-RFLP of groEL and gap genes in comparison to MALDI-TOF mass spectrometry.
Mastitis
Feeding a Saccharomyces cerevisiae fermentation product improves udder health and immune response to a Streptococcus uberis mastitis challenge in mid-lactation dairy cows.
Mastitis
Identification of coagulase-negative staphylococci from bovine mastitis using RFLP-PCR of the groEL gene.
Mastitis
Mutations in HSP70-2 gene change the susceptibility to clinical mastitis in Chinese Holstein.
Mastitis
Use of primers based on the heat shock protein genes hsp70, hsp40, and hsp10, for the detection of bovine mastitis pathogens Streptococcus agalactiae, Streptococcus uberis and Streptococcus bovis.
Mastitis
[Genetic polymorphism of HSP70-1 gene and its correlation with resistance to mastitis in Chinese Holstein]
Mastocytoma
Tumor cell membrane-bound heat shock protein 70 elicits antitumor immunity.
Measles
A single codon in the nucleocapsid protein C terminus contributes to in vitro and in vivo fitness of edmonston measles virus.
Measles
Autophagy induction by the pathogen receptor NECTIN4 and sustained autophagy contribute to peste des petits ruminants virus infectivity.
Measles
Cancer and Virus Leads by HTS, Chemical Design and SEA Data Mining.
Measles
Constitutive overexpression of the major inducible 70 kDa heat shock protein mediates large plaque formation by measles virus.
Measles
Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation.
Measles
Heat shock protein inhibitors increase the efficacy of measles virotherapy.
Measles
High affinity binding between Hsp70 and the C-terminal domain of the measles virus nucleoprotein requires an Hsp40 co-chaperone.
Measles
hsp70 and a novel axis of type I interferon-dependent antiviral immunity in the measles virus-infected brain.
Measles
hsp70-Dependent Antiviral Immunity against Cytopathic Neuronal Infection by Vesicular Stomatitis Virus.
Measles
Hsp72 recognizes a P binding motif in the measles virus N protein C-terminus.
Measles
HSP90 Chaperoning in Addition to Phosphoprotein Required for Folding but Not for Supporting Enzymatic Activities of Measles and Nipah Virus L Polymerases.
Measles
Live Attenuated Measles Virus Vaccine Expressing Helicobacter pylori Heat Shock Protein A.
Measles
Modulation of Measles Virus NTAIL Interactions through Fuzziness and Sequence Features of Disordered Binding Sites.
Measles
Molecular mimicry between varicella, measles virus and Hsp60 in type 1 diabetes associated HLA-DR3/DR4 molecules.
Medulloblastoma
Expression of heat shock proteins in medulloblastoma.
Medulloblastoma
Immunoexpression patterns for Hypoxia-inducible Factor-1? and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
Medulloblastoma
Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.
Medulloblastoma
Integrated proteomic platforms for the comparative characterization of medulloblastoma and pilocytic astrocytoma pediatric brain tumors: a preliminary study.
Megalencephaly
MR imaging and 1H-MR spectroscopy in a case of juvenile Alexander disease.
Melanoma
17-(Allylamino)-17-demethoxygeldanamycin activity in human melanoma models.
Melanoma
17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.
Melanoma
17-AAG inhibits vemurafenib-associated MAP kinase activation and is synergistic with cellular immunotherapy in a murine melanoma model.
Melanoma
17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-?B) Activity in Patient-Derived Melanoma Cell Lines.
Melanoma
17-Aminogeldanamycin selectively diminishes IRE1?-XBP1s pathway activity and cooperatively induces apoptosis with MEK1/2 and BRAFV600E inhibitors in melanoma cells of different genetic subtypes.
Melanoma
1?,25(OH)(2) D(3) enhances NK susceptibility of human melanoma cells through the enhancement of Hsp60-mediated FAS expression.
Melanoma
2-Methoxyestradiol and Its Combination with a Natural Compound, Ferulic Acid, Induces Melanoma Cell Death via Downregulation of Hsp60 and Hsp90.
Melanoma
2-phenylethynesulphonamide (PFT-?) enhances the anticancer effect of the novel hsp90 inhibitor NVP-AUY922 in melanoma, by reducing GSH levels.
Melanoma
A Mortalin/HSPA9-Mediated Switch in Tumor-Suppressive Signaling of Raf/MEK/Extracellular Signal-Regulated Kinase.
Melanoma
A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice.
Melanoma
A novel C-terminal HSP90 inhibitor KU135 induces apoptosis and cell cycle arrest in melanoma cells.
Melanoma
A novel C-terminal Hsp90 inhibitor KU758 synergizes efficacy in combination with BRAF or MEK inhibitors and targets drug-resistant pathways in BRAF-mutant melanomas.
Melanoma
A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells.
Melanoma
A novel DNA vaccine constructed by heat shock protein 70 and melanoma antigen-encoding gene 3 against tumorigenesis.
Melanoma
A Phase II trial of 17-allylamino, 17-demethoxygeldanamycin (17-AAG, tanespimycin) in patients with metastatic melanoma.
Melanoma
A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-alpha in metastatic melanoma patients.
Melanoma
A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion.
Melanoma
Aberrant DNA methylation silences the novel heat shock protein H11 in melanoma but not benign melanocytic lesions.
Melanoma
Activity of the heat shock protein 90 inhibitor ganetespib in melanoma.
Melanoma
Acute extracellular acidification increases nuclear associated protein levels in human melanoma cells during 42 degrees C hyperthermia and enhances cell killing.
Melanoma
Administration of heat shock protein 65 inhibits murine melanoma growth in vivo.
Melanoma
An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.
Melanoma
Analysis of candidate genes through a proteomics-based approach in primary cell lines from malignant melanomas and their metastases.
Melanoma
Antitumor agent 25-epi Ritterostatin GN1N induces endoplasmic reticulum stress and autophagy mediated cell death in melanoma cells.
Melanoma
Antitumor effects of combined therapy of recombinant heat shock protein 70 and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanoma.
Melanoma
Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma.
Melanoma
Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.
Melanoma
BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors.
Melanoma
Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.
Melanoma
Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.
Melanoma
Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survival.
Melanoma
Clinical Significance of Circulating Serum Cellular Heat Shock Protein 90 (HSP90) Level in Patients with Cutaneous Malignant Melanoma
Melanoma
Columbamine suppresses proliferation and invasion of melanoma cell A375 via HSP90-mediated STAT3 activation.
Melanoma
Combination of ionising radiation with hyperthermia increases the immunogenic potential of B16-F10 melanoma cells in vitro and in vivo.
Melanoma
Combined BRAF and HSP90 Inhibition in Patients with Unresectable BRAFV600E-Mutant Melanoma.
Melanoma
Combined effects of the proteasome inhibitor bortezomib and Hsp70 inhibitors on the B16F10 melanoma cell line.
Melanoma
Combined inhibition of Hsp90 and heme oxygenase-1 induces apoptosis and endoplasmic reticulum stress in melanoma.
Melanoma
Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
Melanoma
Constitutive expression of the heat shock protein 72 kDa in human melanoma cells.
Melanoma
Dangerous liaisons: flirtations between oncogenic BRAF and GRP78 in drug-resistant melanomas.
Melanoma
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3K?) against cutaneous melanoma.
Melanoma
Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging.
Melanoma
Development of a Bifunctional Andrographolide-Based Chemical Probe for Pharmacological Study.
Melanoma
Diagnostic and prognostic value of heat shock protein 90? in malignant melanoma.
Melanoma
Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens.
Melanoma
Differential effect of acute and permanent heat shock protein 70 overexpression in tumor cells on lysability by cytotoxic T lymphocytes.
Melanoma
Differential expression of heat shock protein 105 in melanoma and melanocytic naevi.
Melanoma
Discovery of N-pyridoyl-?2 -pyrazolines as Hsp90 inhibitors.
Melanoma
DNAJB6 governs a novel regulatory loop determining Wnt/?-catenin signalling activity.
Melanoma
Dominant negative Rac1 attenuates paclitaxel-induced apoptosis in human melanoma cells through upregulation of heat shock protein 27: a functional proteomic analysis.
Melanoma
Early development of PAT-SM6 for the treatment of melanoma.
Melanoma
Effect of antiangiogenic therapy on luciferase activity in a cytomegalovirus- or HSP70-promoter-transfected M21 tumor model.
Melanoma
Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state.
Melanoma
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Melanoma
Enhanced susceptibility to cytotoxic T lymphocytes without increase of MHC class I antigen expression after conditional overexpression of heat shock protein 70 in target cells.
Melanoma
Enhanced T-cell activation by immature dendritic cells loaded with HSP70-expressing heat-killed melanoma cells.
Melanoma
Enhancing the treatment effect on melanoma by heat shock protein 70-peptide complexes purified from human melanoma cell lines.
Melanoma
ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma.
Melanoma
Erythroid Differentiation Regulator 1, an Interleukin 18-Regulated Gene, Acts as a Metastasis Suppressor in Melanoma.
Melanoma
Evaluating melanoma drug response and therapeutic escape with quantitative proteomics.
Melanoma
Evaluation of [11C]NMS-E973 as a PET tracer for in vivo visualisation of HSP90.
Melanoma
Expression of chemoresistance-related genes and heat shock protein 72 in hyperthermic isolated limb perfusion of malignant melanoma: an experimental study.
Melanoma
Expression of focal adhesion kinase in uveal melanoma and the effects of Hsp90 inhibition by 17-AAG.
Melanoma
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma.
Melanoma
Expression of heat shock protein 105 and 70 in malignant melanoma and benign melanocytic nevi.
Melanoma
Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study.
Melanoma
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Melanoma
Expression of the CD117, COX-2 and HSP90 antigens and cell proliferation in fine-needle-aspirated cells from metastatic melanomas.
Melanoma
Expression of the heat shock cognate protein HSP73 correlates with tumour thickness of primary melanomas and is enhanced in melanoma metastases.
Melanoma
Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis.
Melanoma
Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma.
Melanoma
Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines.
Melanoma
Geldanamycin and its anti-cancer activities.
Melanoma
Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells.
Melanoma
Green fluorescent protein as a marker for monitoring activity of stress-inducible hsp70 rat gene promoter.
Melanoma
Heat shock cognate protein 71-associated peptides function as an epitope for Toxoplasma gondii-specific CD4+ CTL.
Melanoma
Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma.
Melanoma
Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Melanoma
Heat shock protein 90 inhibitor enhances apoptosis by inhibiting the AKT pathway in thermal-stimulated SK-MEL-2 human melanoma cell line.
Melanoma
Heat shock protein expression in the eye and in uveal melanoma.
Melanoma
Heat shock protein peptide complex 96-based vaccines in melanoma: How far we are, how far we can get.
Melanoma
Heat shock protein-90 inhibitors enhance antigen expression on melanomas and increase T cell recognition of tumor cells.
Melanoma
Heat-induced modulation of lamin B content in two different cell lines.
Melanoma
Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.
Melanoma
Heterogeneous patterns of constitutive and heat shock induced expression of HLA-linked HSP70-1 and HSP70-2 heat shock genes in human melanoma cell lines.
Melanoma
HSP-27 protein expression in uveal melanoma: correlation with predicted survival.
Melanoma
HSP27 Expression as a Novel Predictive Biomarker for Bevacizumab: is it Cost Effective?
Melanoma
HSP90 as a marker of progression in melanoma.
Melanoma
Hsp90 as a Potential Therapeutic Target in Retinal Disease.
Melanoma
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.
Melanoma
Hyperthermia enhances CTL cross-priming.
Melanoma
Identification of a 66 kD heat shock protein (HSP) induced in M-14 human melanoma cells by severe hyperthermic treatment.
Melanoma
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine.
Melanoma
Imaging of Firefly Luciferase Activity under Antiangiogenic Therapy in a Heat Shock Protein 70-Transfected Melanoma Tumor Model.
Melanoma
Immune expression and inhibition of heat shock protein 90 in uveal melanoma.
Melanoma
Immunohistochemical expression of C-myc oncogene, heat shock protein 70 and HLA-DR molecules in malignant cutaneous melanoma.
Melanoma
In Vitro and In Vivo Studies of the Biological Effects of Bioceramic (a Material of Emitting High Performance Far-Infrared Ray) Irradiation.
Melanoma
Induction of heat shock protein 70 genes in human lymphocytes during fever therapy.
Melanoma
Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases.
Melanoma
Induction of the 72-kD heat shock protein in human skin melanoma and squamous cell carcinoma cell lines.
Melanoma
Inhibiting HSP90 prevents the induction of myeloid-derived suppressor cells by melanoma cells.
Melanoma
Inhibition of Cancer Cell Growth by GRP78 siRNA Lipoplex via Activation of Unfolded Protein Response.
Melanoma
Inhibition of endoplasmic reticulum stress-induced autophagy sensitizes melanoma cells to temozolomide treatment.
Melanoma
Inhibition of heat shock protein 90 sensitizes melanoma cells to thermosensitive ferromagnetic particle-mediated hyperthermia with low Curie temperature.
Melanoma
Inhibition of Hsp90 and 70 sensitizes melanoma cells to hyperthermia using ferromagnetic particles with a low Curie temperature.
Melanoma
Inhibition of HSP90 by AT13387 delays the emergence of resistance to BRAF inhibitors and overcomes resistance to dual BRAF and MEK inhibition in melanoma models.
Melanoma
Inhibition of mouse RM-1 prostate cancer and B16F10 melanoma by the fusion protein of HSP65 & STEAP1 186-193.
Melanoma
Inhibition of telomerase activity by geldanamycin and 17-allylamino, 17-demethoxygeldanamycin in human melanoma cells.
Melanoma
Inhibition of Wee1, AKT and CDK4 underlies the efficacy of the HSP90 inhibitor XL888 in an in vivo model of NRAS mutant melanoma.
Melanoma
Inhibitors of HSP90 in melanoma.
Melanoma
Intracellular acidification abrogates the heat shock response and compromises survival of human melanoma cells.
Melanoma
Introduction of 65 kDa antigen of Mycobacterium tuberculosis to cancer cells enhances anti-tumor effect of BCG therapy.
Melanoma
Involvement of ER stress and activation of apoptotic pathways in fisetin induced cytotoxicity in human melanoma.
Melanoma
iTRAQ Quantitative Proteomic Comparison of Metastatic and Non-Metastatic Uveal Melanoma Tumors.
Melanoma
Killing of normal melanocytes, combined with heat shock protein 70 and CD40L expression, cures large established melanomas.
Melanoma
Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis.
Melanoma
Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells.
Melanoma
mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.
Melanoma
MDA-9 and GRP78 as potential diagnostic biomarkers for early detection of melanoma metastasis.
Melanoma
Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion.
Melanoma
Melanoma and lymphocyte cell-specific targeting incorporated into a heat shock protein cage architecture.
Melanoma
Melanoma and the Unfolded Protein Response.
Melanoma
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Melanoma
Modulation of Diacylglycerol-Induced Melanogenesis in Human Melanoma and Primary Melanocytes: Role of Stress Chaperone Mortalin.
Melanoma
Modulation of heat shock protein synthesis in two human melanoma cell lines.
Melanoma
Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition.
Melanoma
Modulation of Plasma Membrane Composition and Microdomain Organization Impairs Heat Shock Protein Expression in B16-F10 Mouse Melanoma Cells.
Melanoma
Molecular oncogene markers and their significance in cutaneous malignant melanoma.
Melanoma
Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis.
Melanoma
Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-RafV600E melanoma cells.
Melanoma
NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG.
Melanoma
Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis.
Melanoma
Overcoming acquired BRAF inhibitor resistance in melanoma via targeted inhibition of Hsp90 with ganetespib.
Melanoma
Overexpression of Hsp25 in K1735 murine melanoma cells enhances susceptibility to natural killer cytotoxicity.
Melanoma
Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro.
Melanoma
Patterns of GRP78 and MTJ1 expression in primary cutaneous malignant melanoma.
Melanoma
Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma.
Melanoma
Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group.
Melanoma
Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma.
Melanoma
Phenotypic identification of the redox dye methylene blue as an antagonist of heat shock response gene expression in metastatic melanoma cells.
Melanoma
Platelet count correlates with stage and predicts survival in melanoma.
Melanoma
Potential diagnostic significance of HSP90, ACS/TMS1, and L-plastin in the identification of melanoma.
Melanoma
Prognostic implications of markers of the metabolic phenotype in human cutaneous melanoma.
Melanoma
Prophylactic Admission of an In Vitro Reconstructed Complexes of Human Recombinant Heat Shock Proteins and Melanoma Antigenic Peptides Activates Anti-Melanoma Responses in Mice.
Melanoma
Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells.
Melanoma
Proteomic investigation of the sinulariolide-treated melanoma cells A375: effects on the cell apoptosis through mitochondrial-related pathway and activation of caspase cascade.
Melanoma
Recent Patents on Heat Shock Proteins Targeting Antibodies.
Melanoma
Regulation of stability of cyclin-dependent kinase CDK11p110 and a caspase-processed form, CDK11p46, by Hsp90.
Melanoma
Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways.
Melanoma
Results from phase II trial of HSP90 inhibitor, STA-9090 (ganetespib), in metastatic uveal melanoma.
Melanoma
Retraction notice to "A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells".
Melanoma
SNX-2112, an Hsp90 inhibitor, induces apoptosis and autophagy via degradation of Hsp90 client proteins in human melanoma A-375 cells.
Melanoma
Steady-State Levels of Phosphorylated Mitogen-Activated Protein Kinase Kinase 1/2 Determined by Mortalin/HSPA9 and Protein Phosphatase 1 Alpha in KRAS and BRAF Tumor Cells.
Melanoma
Suppression of murine melanoma growth by a vaccine of attenuated Salmonella carrying heat shock protein 70 and Herpes simplex virus-thymidine kinase genes.
Melanoma
Synergistic anti-tumor effect of 17AAG with the PI3K/mTOR inhibitor NVP-BEZ235 on human melanoma.
Melanoma
Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.
Melanoma
Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.
Melanoma
Targeting GRP78 to enhance melanoma cell death.
Melanoma
The Broad Stroke of Hsp90 Inhibitors: Painting over the RAF Inhibitor Paradox.
Melanoma
The common heat shock protein receptor CD91 is up-regulated on monocytes of advanced melanoma slow progressors.
Melanoma
The Escherichia coli Subtilase Cytotoxin A Subunit Specifically Cleaves Cell-Surface GRP78 and Abolishes COOH-Terminal-Dependent Signaling.
Melanoma
The heat shock protein-90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms.
Melanoma
The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor.
Melanoma
The Potential of Targeting P53 and HSP90 Overcoming Acquired MAPKi-Resistant Melanoma.
Melanoma
Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle.
Melanoma
TRAIL-induced apoptosis of human melanoma cells involves activation of caspase-4.
Melanoma
Tumor antigen delivered by Salmonella III secretion protein fused with heat shock protein 70 induces protection and eradication against murine melanoma.
Melanoma
Unbiased High-Throughput Drug Combination Pilot Screening Identifies Synergistic Drug Combinations Effective against Patient-Derived and Drug-Resistant Melanoma Cell Lines.
Melanoma
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors.
Melanoma
Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings.
Melanoma
[Biodistribution of the recombinant heat shock protein rhHsp70 in intracranial C6 glioma models in Wistar rats and subcutaneos B16/F10 melanoma in C57BL/6 mice].
Melanoma
[Butein promotes the role of mH2A in MAPK signaling pathway through targeting GRP78 in regulating biological behaviors of melanoma].
Melanoma
[Intratumor injection of recombinant attenuated salmonella carrying Mycobacterium tuberculosis heat shock protein 70 and herpes simplex virus thymidine kinase genes to suppress murine melanoma growth].
Melanoma, Experimental
Fusion protein of ATPase domain of Hsc70 with TRP2 acting as a tumor vaccine against B16 melanoma.
Melanoma, Experimental
Heat shock protein levels are not elevated in heat-resistant B16 melanoma cells.
Melanoma, Experimental
The heat shock protein 90 inhibitor SNX-2112 inhibits B16 melanoma cell growth in vitro and in vivo.
MELAS Syndrome
Activation of the mitochondrial protein quality control system and actin cytoskeletal alterations in cells harbouring the MELAS mitochondrial DNA mutation.
Melioidosis
groEL encodes a highly antigenic protein in Burkholderia pseudomallei.
Melioidosis
Production and evaluation of recombinant Burkholderia pseudomallei GroEL and OmpA proteins for serodiagnosis of melioidosis.
Melioidosis
Seronegative bacteremic melioidosis caused by Burkholderia pseudomallei with ambiguous biochemical profile: clinical importance of accurate identification by 16S rRNA gene and groEL gene sequencing.
Memory Disorders
A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.
Memory Disorders
Heat Shock Cognate 70 Inhibitor, VER-155008, Reduces Memory Deficits and Axonal Degeneration in a Mouse Model of Alzheimer's Disease.
Memory Disorders
Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation.
Meniere Disease
Failure of elevated heat shock protein 70 antibodies to alter cochlear function in mice.
Meniere Disease
HSP70 antibodies in 80 patients with "clinically certain" Meniere's disease.
Meniere Disease
Polymorphic analysis of the heat-shock protein 70 gene (HSPA1A) in Ménière's disease.
Meniere Disease
Polymorphic analysis of the heat-shock protein 70 gene (HSPA1A) in Meniere's disease.
Meniere Disease
Prevalence of heat shock protein in patients with Meniere's disease and allergy.
Meniere Disease
Recognition of a dominant epitope in bovine heat-shock protein 70 in inner ear disease.
Meniere Disease
Viral infection and serum antibodies to heat shock protein 70 in the acute phase of Ménière's disease.
Meningeal Neoplasms
Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis.
Meningioma
Elevated levels of mortalin expression in human brain tumors.
Meningioma
Expression of heat shock proteins in brain tumors.
Meningioma
Human meningiomas: immunohistochemical localization of progesterone receptor and heat shock protein 27 and absence of estrogen receptor and PS2.
Meningioma
Wild type and alternatively spliced estrogen receptor messenger RNA in human meningioma tissue and MCF7 breast cancer cells.
Meningioma
[Changes in the cytokine profile in patients with supratentorial meningiomas].
Meningitis
A pilot study to detect high mobility group box 1 and heat shock protein 72 in cerebrospinal fluid of pediatric patients with meningitis.
Meningitis
Hypothermia decreases excitatory neurotransmitter release in bacterial meningitis in rabbits.
Meningitis
Superior adjuvanticity of the genetically fused D1 domain of Neisseria meningitides Ag473 lipoprotein among three Toll-like receptor ligands.
Meningitis, Bacterial
Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children.
Meningitis, Pneumococcal
Anti-inflammatory and Oto-Protective Effect of the Small Heat Shock Protein Alpha B-Crystallin (HspB5) in Experimental Pneumococcal Meningitis.
Meningitis, Pneumococcal
Experimental pneumococcal meningitis causes central nervous system pathology without inducing the 72-kd heat shock protein.
Meningococcal Infections
Glutamine depletion and heat shock protein 70 (HSP70) in children with meningococcal disease.
Meningococcal Infections
Immunogenicity of the meningococcal stress protein MSP63 during natural infection.
Meningoencephalitis
The unfolded protein response (UPR) pathway in Cryptococcus.
Menkes Kinky Hair Syndrome
Cerebellar expression of copper chaperone for superoxide, cytosolic cu/zn-superoxide dismutase, 4-hydroxy-2-nonenal, acrolein and heat shock protein 32 in patients with menkes kinky hair disease: immunohistochemical study.
MERRF Syndrome
Decreased heat shock protein 27 expression and altered autophagy in human cells harboring A8344G mitochondrial DNA mutation.
MERRF Syndrome
The protective roles of phosphorylated heat shock protein?27 in human cells harboring myoclonus epilepsy with ragged-red fibers A8344G mtDNA mutation.
Mesenteric Ischemia
Can heat shock protein 32 be used for the early diagnosis of acute mesenteric ischemia?
Mesenteric Ischemia
Ergothioneine modulates proinflammatory cytokines and heat shock protein 70 in mesenteric ischemia and reperfusion injury.
Mesenteric Ischemia
The value of endoplasmic reticulum stress markers (GRP78 and CHOP) in the diagnosis of acute mesenteric ischemia.
Mesothelioma
(-)- Epigallocatechin-3-gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress.
Mesothelioma
A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma.
Mesothelioma
Cytotoxic T cell responses against mesothelioma by apoptotic cell-pulsed dendritic cells.
Mesothelioma
Functional inhibition of heat shock protein 70 by VER-155008 suppresses pleural mesothelioma cell proliferation via an autophagy mechanism.
Mesothelioma
HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome.
Mesothelioma
Increased expression of heat shock protein 70 in adherent ovarian cancer and mesothelioma following treatment with manumycin, a farnesyl transferase inhibitor.
Mesothelioma
Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma.
Mesothelioma
Mesothelial cells activate the plasma kallikrein-kinin system during pleural inflammation.
Mesothelioma
Mesothelioma cells escape heat stress by upregulating Hsp40/Hsp70 expression via mitogen-activated protein kinases.
Mesothelioma
Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma.
Mesothelioma, Malignant
HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome.
Mesothelioma, Malignant
Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma.
Metabolic Diseases
Intracellular localization of HSP73 and HSP90 in rat kidneys with acute lysosomal thesaurismosis.
Metabolic Diseases
N-Formyl-3,4-methylenedioxy-benzylidene-gamma-butyrolaetam, KNK437 induces caspase-3 activation through inhibition of mTORC1 activity in Cos-1 cells.
Metabolic Diseases
Plasma HSP70 Levels Correlate with Health Risk Factors and Insulin Resistance in African American Subjects.
Metabolic Syndrome
A cross-sectional study of the association between heat shock protein 27 antibody titers, pro-oxidant-antioxidant balance and metabolic syndrome in patients with angiographically-defined coronary artery disease.
Metabolic Syndrome
Clusterin and Its Role in Insulin Resistance and the Cardiometabolic Syndrome.
Metabolic Syndrome
Improved Metabolic Control in Diabetes, HSP60, and Proinflammatory Mediators.
Metabolic Syndrome
Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells.
Metabolic Syndrome
Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials.
Metabolic Syndrome
Omega-3 fatty acid supplements improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity.
Metabolic Syndrome
Oxidative stress markers, C-reactive protein and heat shock protein 70 levels in subjects with metabolic syndrome.
Metabolic Syndrome
Relationship Between Heat Shock Protein Expression and Obesity With and Without Metabolic Syndrome.
Metabolic Syndrome
The 60- and 70-kDa heat-shock proteins and their correlation with cardiovascular risk factors in postmenopausal women with metabolic syndrome.
Metabolic Syndrome
The Effects of Curcumin on Serum Heat Shock Protein 27 Antibody Titers in Patients with Metabolic Syndrome.
Metabolic Syndrome
The effects of wet cupping on serum high-sensitivity C-reactive protein and heat shock protein 27 antibody titers in patients with metabolic syndrome.
Microphthalmos
Hsp90 selectively modulates phenotype in vertebrate development.
Microscopic Polyangiitis
Increased concentrations of antibody against heat shock protein in patients with myeloperoxidase anti-neutrophil cytoplasmic autoantibody positive microscopic polyangiitis.
Migraine Disorders
Elevated interictal serum HSP-70 levels as an indicator of neurodegeneration for chronic migraine.
Migraine Disorders
Exogenous HSP70 attenuates nitroglycerin-induced migraine-like symptoms in mice.
Migraine Disorders
[Herbs for calming liver and suppressing liver-yang in treatment of migraine with hyperactive liver-yang syndrome and its effects on lymphocyte protein expression: a randomized controlled trial]
Milk Hypersensitivity
Prevalence of heat shock protein in patients with Meniere's disease and allergy.
Mitochondrial Diseases
A new case of multiple mitochondrial enzyme deficiencies with decreased amount of heat shock protein 60.
Mitochondrial Diseases
Decreased synthesis and inefficient mitochondrial import of hsp60 in a patient with a mitochondrial encephalomyopathy.
Mitochondrial Diseases
Immunolabelling of mitochondrial superoxide dismutase and of Hsp60 in muscles harbouring a respiratory chain deficiency.
Mitochondrial Diseases
Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations.
Mitochondrial Diseases
Spondyloepimetaphyseal dysplasia with neurodegeneration associated with AIFM1 mutation - a novel phenotype of the mitochondrial disease.
Mitochondrial Encephalomyopathies
Decreased synthesis and inefficient mitochondrial import of hsp60 in a patient with a mitochondrial encephalomyopathy.
Mitochondrial Myopathies
Decreased synthesis and inefficient mitochondrial import of hsp60 in a patient with a mitochondrial encephalomyopathy.
Mitochondrial Myopathies
Expression of heat-shock/stress proteins in Duchenne muscular dystrophy.
Mixed Connective Tissue Disease
Antibodies to small ribonucleoprotein and to 73-kD heat shock protein: two distinct markers of mixed connective tissue disease.
Mixed Connective Tissue Disease
Antibodies to the constitutive 73-kd heat shock protein: a new marker of mixed connective tissue disease?
Mixed Connective Tissue Disease
Autoantibodies against chaperonin CCT in human sera with rheumatic autoimmune diseases: comparison with antibodies against other Hsp60 family proteins.
Mixed Connective Tissue Disease
Autoantibodies to human stress proteins. A survey of various rheumatic and other inflammatory diseases.
Mixed Connective Tissue Disease
Identification of citrullinated heat shock protein 90 isoforms as novel autoantigens in rheumatoid arthritis-associated interstitial lung disease.
Monoclonal Gammopathy of Undetermined Significance
Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma.
Monoclonal Gammopathy of Undetermined Significance
STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90alpha and beta in multiple myeloma cells, which critically contribute to tumor-cell survival.
Motor Neuron Disease
Autoantibodies against HSP70 family proteins were detected in the cerebrospinal fluid from patients with multiple sclerosis.
Motor Neuron Disease
Characterization of human small heat shock protein HSPB1 ?-crystallin domain localized mutants associated with hereditary motor neuron diseases.
Motor Neuron Disease
Characterization of human small heat shock protein HspB1 that carries C-terminal domain mutations associated with hereditary motor neuron diseases.
Motor Neuron Disease
Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases.
Motor Neuron Disease
Expression of the human groEL stress-protein homologue in the brain and spinal cord.
Motor Neuron Disease
Mutant HSPB1 overexpression in neurons is sufficient to cause age-related motor neuronopathy in mice.
Motor Neuron Disease
Nonsteroidal anti-inflammatory drugs differentially affect the heat shock response in cultured spinal cord cells.
Motor Neuron Disease
Prevalence of anti-heat shock protein antibodies in cerebrospinal fluids of patients with Guillain-Barré syndrome.
Motor Neuron Disease
Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases.
Mouth Neoplasms
Anti-growth and pro-apoptotic effects of dasatinib on human oral cancer cells through multi-targeted mechanisms.
Mouth Neoplasms
Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells.
Mouth Neoplasms
Cell surface expression of 70 kDa heat shock protein in human oral dysplasia and squamous cell carcinoma: correlation with clinicopathological features.
Mouth Neoplasms
Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan.
Mouth Neoplasms
Differential gene expression in neoplastic and human papillomavirus-immortalized oral keratinocytes.
Mouth Neoplasms
Heat Shock Protein 70 Membrane Expression in Oral Cancer: A Possible New Target in Antineoplastic Therapy?
Mouth Neoplasms
Heat shock protein induced TCR gammadelta gene rearrangements in patients with oral cancer.
Mouth Neoplasms
Low-level laser therapy can produce increased aggressiveness of dysplastic and oral cancer cell lines by modulation of Akt/mTOR signaling pathway.
Mouth Neoplasms
Positive association of glucose-regulated protein 78 during oral cancer progression and the prognostic value in oral precancerous lesions.
Mouth Neoplasms
Prognosis and predictive value of heat-shock proteins expression in oral cancer: A PRISMA-compliant meta-analysis.
Mouth Neoplasms
Prognostic significance of heat shock protein 70 (HSP70) in patients with oral cancer.
Mouth Neoplasms
Serum HSP90-Alpha and Oral Squamous Cell Carcinoma : A Prospective Biomarker.
Mouth Neoplasms
Targeting oral cancer stemness and chemoresistance by isoliquiritigenin-mediated GRP78 regulation.
Movement Disorders
Mortalin inhibition in experimental Parkinson's disease.
Movement Disorders
The early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitro.
Mucocutaneous Lymph Node Syndrome
Heat shock protein as a predisposing and immunopotentiating factor in Kawasaki disease.
Mucocutaneous Lymph Node Syndrome
HSP60, HSP70 in the pathogenesis of Kawasaki disease: implication and action.
Mucocutaneous Lymph Node Syndrome
Increased expression of human 63-kD heat shock protein gene in Kawasaki disease determined by quantitative reverse transcription-polymerase chain reaction.
Mucocutaneous Lymph Node Syndrome
Levels of intra- and extracellular heat shock protein 60 in Kawasaki disease patients treated with intravenous immunoglobulin.
Mucocutaneous Lymph Node Syndrome
Serum biomarkers differentiating Kawasaki disease from febrile infections: A pilot case-control study.
Mucocutaneous Lymph Node Syndrome
T cells recognize an immunodominant epitope of heat shock protein 65 in Kawasaki disease.
Mucormycosis
Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis.
Mucormycosis
CotH3 mediates fungal invasion of host cells during mucormycosis.
Mucormycosis
COVID19 associated mucormycosis: Is GRP78 a possible link?
Mucormycosis
GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis.
Mucormycosis
The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.
Multiple Myeloma
A GRP78-directed monoclonal antibody recaptures response in refractory multiple myeloma with extramedullary involvement.
Multiple Myeloma
A phase I/II study of KW-2478, an Hsp90 inhibitor, in combination with bortezomib in patients with relapsed/refractory multiple myeloma.
Multiple Myeloma
An activated JAK/STAT3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma.
Multiple Myeloma
Analysis of expression of heat shock protein-90 (HSP90) and the effects of HSP90 inhibitor (17-AAG) in multiple myeloma.
Multiple Myeloma
Anti-myeloma activity of the novel 2-aminothienopyrimidine Hsp90 inhibitor NVP-BEP800.
Multiple Myeloma
Anti-tumor activity against multiple myeloma by combination of KW-2478, an Hsp90 inhibitor, with bortezomib.
Multiple Myeloma
Antimyeloma activity of heat shock protein-90 inhibition.
Multiple Myeloma
Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90.
Multiple Myeloma
ATP analog enhances the actions of a HSP90 inhibitor in multiple myeloma cells.
Multiple Myeloma
Azacytidine induces necrosis of multiple myeloma cells through oxidative stress.
Multiple Myeloma
BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth.
Multiple Myeloma
Bortezomib promotes apoptosis of multiple myeloma cells by regulating HSP27.
Multiple Myeloma
Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Multiple Myeloma
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Multiple Myeloma
Glucose-regulated protein 78 (GRP78) as a potential novel biomarker and therapeutic target in multiple myeloma.
Multiple Myeloma
GRP78 modulates cell adhesion markers in prostate Cancer and multiple myeloma cell lines.
Multiple Myeloma
Heat shock protein-90 inhibitors increase MHC class I-related chain a and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation.
Multiple Myeloma
Heat shock proteins in multiple myeloma.
Multiple Myeloma
High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma.
Multiple Myeloma
HSP90 inhibitors as therapy for multiple myeloma.
Multiple Myeloma
Hsp90: a novel target for cancer therapy.
Multiple Myeloma
IL-6 activated JAK/STAT3 pathway and sensitivity to Hsp90 inhibitors in multiple myeloma.
Multiple Myeloma
Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers.
Multiple Myeloma
Inhibition of Heat Shock Protein 90 as a Novel Platform for the Treatment of Cancer.
Multiple Myeloma
Inhibition of HSP90 overcomes melphalan resistance through downregulation of Src in multiple myeloma cells.
Multiple Myeloma
Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors.
Multiple Myeloma
IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells.
Multiple Myeloma
Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma.
Multiple Myeloma
Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma.
Multiple Myeloma
Molecularly targeted therapies in multiple myeloma.
Multiple Myeloma
New Molecular and Biological Mechanism of Antitumor Activities of KW-2478, a Novel Nonansamycin Heat Shock Protein 90 Inhibitor, in Multiple Myeloma Cells.
Multiple Myeloma
Novel biologically based therapies for Waldenstrom's macroglobulinemia.
Multiple Myeloma
Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors.
Multiple Myeloma
Phase 1/1B trial of the heat shock protein 90 inhibitor NVP-AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma.
Multiple Myeloma
Preclinical activity of the novel orally bioavailable HSP90 inhibitor NVP-HSP990 against multiple myeloma cells.
Multiple Myeloma
Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma.
Multiple Myeloma
Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.
Multiple Myeloma
Proteomic and Functional Analyses Reveal a Dual Molecular Mechanism Underlying Arsenic-Induced Apoptosis in Human Multiple Myeloma Cells.
Multiple Myeloma
Signalling profile and antitumour activity of the novel Hsp90 inhibitor NVP-AUY922 in multiple myeloma.
Multiple Myeloma
SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK.
Multiple Myeloma
Spliced XBP1 Levels Determine Sensitivity of Multiple Myeloma Cells to Proteasome Inhibitor Bortezomib Independent of the Unfolded Protein Response Mediator GRP78.
Multiple Myeloma
Stew in its Own Juice: Protein Homeostasis Machinery Inhibition Reduces Cell Viability in Multiple Myeloma Cell Lines.
Multiple Myeloma
Synergistic action of the novel HSP90 inhibitor NVP-AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma.
Multiple Myeloma
Synergistic effects of rmhTRAIL and 17-AAG on the proliferation and apoptosis of multiple myeloma cells.
Multiple Myeloma
Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment.
Multiple Myeloma
Targeting heat shock protein 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma.
Multiple Myeloma
The 60-kDa heat shock protein regulates energy rearrangement and protein synthesis to promote proliferation of multiple myeloma cells.
Multiple Myeloma
The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1.
Multiple Myeloma
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Multiple Myeloma
The natural human IgM antibody PAT-SM6 induces apoptosis in primary human multiple myeloma cells by targeting heat shock protein GRP78.
Multiple Myeloma
The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases.
Multiple Myeloma
The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.
Multiple Myeloma
Transcription inhibition of heat shock proteins: a strategy for combination of 17-allylamino-17-demethoxygeldanamycin and actinomycin d.
Multiple Myeloma
[Correlation of HSP90 mRNA Expression with Migration Ability of Human Multiple Myeloma Cells.]
Multiple Myeloma
[Expression and Clinical Significance of Heat Shock Protein 90 in Multiple Myeloma Patients].
Multiple Myeloma
[Heat shock protein 90 alpha und beta are overexpressed in multiple myeloma cells and critically contribute to survival]
Multiple Myeloma
[HSP90 Inhibitor 17-AAG Inhibits Multiple Myeloma Cell Proliferation by Down-regulating Wnt/?-Catenin Signaling Pathway].
Multiple Myeloma
[Influence of Co-inhibiting mTORC2 and HSP90 on Proliferation Apoptosis of Multiple Myeloma Cells].
Multiple Myeloma
[Research on multiple myeloma cell apoptosis by inhibition of mTORC2 and chaperon pathways].
Multiple Sclerosis
A novel rationale for inhibition of gelatinase B in multiple sclerosis: MMP-9 destroys alpha B-crystallin and generates a promiscuous T cell epitope.
Multiple Sclerosis
Alpha B-crystallin is not a dominant peripheral T-cell autoantigen in multiple sclerosis amongst Sardinians.
Multiple Sclerosis
Alpha beta-crystallin expression and presentation following infection with murine gammaherpesvirus 68.
Multiple Sclerosis
AlphaB-crystallin-reactive T cells from knockout mice are not encephalitogenic.
Multiple Sclerosis
Anti Mycobacterium avium subsp. paratuberculosis heat shock protein 70 antibodies in the sera of Sardinian patients with multiple sclerosis.
Multiple Sclerosis
Antibodies reactive to heat shock protein 90 induce oligodendrocyte precursor cell death in culture. Implications for demyelination in multiple sclerosis.
Multiple Sclerosis
Clinical proteomics in chronic inflammatory diseases: A review.
Multiple Sclerosis
Clonal expansion and decreased occurrence of peripheral blood gamma delta T cells of the V delta 2J delta 3 lineage in multiple sclerosis patients.
Multiple Sclerosis
Colocalization of lymphocytes bearing gamma delta T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis.
Multiple Sclerosis
CRYAB promoter polymorphisms: influence on multiple sclerosis susceptibility and clinical presentation.
Multiple Sclerosis
Cytokine induction of heat shock protein expression in human oligodendrocytes: an interleukin-1-mediated mechanism.
Multiple Sclerosis
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes.
Multiple Sclerosis
Epitopes of microbial and human heat shock protein 60 and their recognition in myalgic encephalomyelitis.
Multiple Sclerosis
Expression of alphaB-crystallin in glia cells during lesional development in multiple sclerosis.
Multiple Sclerosis
Heat shock protein 27 in multiple sclerosis relapses.
Multiple Sclerosis
Heat Shock Protein 70 and The Risk of Multiple Sclerosis in The Iranian Population.
Multiple Sclerosis
Heat shock protein 70 associations with myelin basic protein and proteolipid protein in multiple sclerosis brains.
Multiple Sclerosis
Heat shock protein 70 gene polymorphism in Japanese patients with multiple sclerosis.
Multiple Sclerosis
Heat shock protein 70 gene polymorphisms and multiple sclerosis.
Multiple Sclerosis
Heat shock protein 70-hom gene polymorphism and protein expression in multiple sclerosis.
Multiple Sclerosis
Heat Shock Protein 70: Roles in Multiple Sclerosis.
Multiple Sclerosis
High prevalence of anti-alpha-crystallin antibodies in multiple sclerosis: correlation with severity and activity of disease.
Multiple Sclerosis
Inducible heat shock protein 70 promotes myelin autoantigen presentation by the HLA class II.
Multiple Sclerosis
Patients with multiple sclerosis resisted to glucocorticoid therapy: abnormal expression of heat-shock protein 90 in glucocorticoid receptor complex.
Multiple Sclerosis
Phosphorylation of ?B-crystallin supports reactive astrogliosis in demyelination.
Multiple Sclerosis
Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury.
Multiple Sclerosis
Relevance of Helicobacter pylori infection in Egyptian multiple sclerosis patients.
Multiple Sclerosis
Sequence homologies between hsp60 and autoantigens.
Multiple Sclerosis
Serum heat shock protein 70 levels as a biomarker for inflammatory processes in multiple sclerosis.
Multiple Sclerosis
Spinal fluid lymphocytes from a subgroup of multiple sclerosis patients respond to mycobacterial antigens.
Multiple Sclerosis
The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis.
Multiple Sclerosis
The Reaction of Placental GRP78 Protein with Sera from Women with Multiple Sclerosis.
Multiple Sclerosis
The small heat shock protein alpha B-crystallin as key autoantigen in multiple sclerosis.
Multiple Sclerosis
Therapeutic effects of systemic administration of the chaperone alpha B crystallin associated with binding proinflammatory plasma proteins.
Multiple Sclerosis
Therapeutic Intervention in Multiple Sclerosis with Alpha B-Crystallin: A Randomized Controlled Phase IIa Trial.
Multiple Sclerosis
Transcriptional profiling of microdissected areas of active multiple sclerosis lesions reveals activation of heat shock protein genes.
Multiple Sclerosis
Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.
Multiple Sclerosis
Up-regulation of osteopontin and alphaBeta-crystallin in the normal-appearing white matter of multiple sclerosis: an immunohistochemical study utilizing tissue microarrays.
Multiple Sclerosis
[Heat shock protein 105 in multiple sclerosis]
Multiple Sclerosis, Chronic Progressive
Relevance of Helicobacter pylori infection in Egyptian multiple sclerosis patients.
Multiple System Atrophy
Accumulation of Hsc70 and Hsp70 in glial cytoplasmic inclusions in patients with multiple system atrophy.
Mumps
Airway Papillomatosis: New Treatments for an Old Challenge.
Mumps
Heat Shock Protein 70 Regulates Degradation of the Mumps Virus Phosphoprotein via the Ubiquitin-Proteasome Pathway.
Mumps
Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation.
Muscle Spasticity
Inactivation of the hereditary spastic paraplegia-associated Hspd1 gene encoding the Hsp60 chaperone results in early embryonic lethality in mice.
Muscle Spasticity
Recombinant osteopontin in cerebral vasospasm after subarachnoid hemorrhage.
Muscle Spasticity
The neurodegenerative-disease-related protein sacsin is a molecular chaperone.
Muscle Weakness
Effects of corticosteroids in the development of limb muscle weakness in a porcine intensive care unit model.
Muscular Atrophy
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.
Muscular Atrophy
17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse.
Muscular Atrophy
A transient antioxidant stress response accompanies the onset of disuse atrophy in human skeletal muscle.
Muscular Atrophy
Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).
Muscular Atrophy
Endoplasmic reticulum stress in myotonic dystrophy type 1 muscle.
Muscular Atrophy
Estrogen administration attenuates immobilization-induced skeletal muscle atrophy in male rats.
Muscular Atrophy
Heat shock cognate protein 70 promotes the differentiation of C2C12 myoblast and targets Yin Yang 1.
Muscular Atrophy
Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein.
Muscular Atrophy
Hsp40 molecules that target to the ubiquitin-proteasome system decrease inclusion formation in models of polyglutamine disease.
Muscular Atrophy
Hsp40 Molecules That Target to the Ubiquitin-proteasome System Decrease Inclusion Formation in Models of Polyglutamine Disease.
Muscular Atrophy
Hsp70 prevents disuse muscle atrophy in senescent rats.
Muscular Atrophy
Inhibition of Hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation.
Muscular Atrophy
Mountain ginseng inhibits skeletal muscle atrophy by decreasing muscle RING ?nger protein-1 and atrogin1 through forkhead box O3 in L6 myotubes.
Muscular Atrophy
Overexpression of inducible 70-kDa heat shock protein in mouse improves structural and functional recovery of skeletal muscles from atrophy.
Muscular Atrophy
Physiological and molecular responses to thermal stress in red cusk-eel (Genypterus chilensis) juveniles reveals atrophy and oxidative damage in skeletal muscle.
Muscular Atrophy
Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases.
Muscular Atrophy
The decrease of the cytoskeleton tubulin follows the decrease of the associating molecular chaperone alphaB-crystallin in unloaded soleus muscle atrophy without stretch.
Muscular Atrophy
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Muscular Atrophy, Spinal
HspB1 silences translation of PDZ-RhoGEF by enhancing miR-20a and miR-128 expression to promote neurite extension.
Muscular Diseases
?B-Crystallin R120G variant causes cardiac arrhythmias and alterations in the expression of Ca(2+) -handling proteins and endoplasmic reticulum stress in mice.
Muscular Diseases
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy.
Muscular Diseases
BAG3 Directly Interacts with Mutated alphaB-Crystallin to Suppress Its Aggregation and Toxicity.
Muscular Diseases
Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice.
Muscular Diseases
Expression, localization and functional divergence of alphaB-crystallin and heat shock protein 27 in core myopathies and neurogenic atrophy.
Muscular Diseases
Glucocorticoid treatment induces expression of small heat shock proteins in human satellite cell populations: consequences for a desmin-related myopathy involving the R120G alpha B-crystallin mutation.
Muscular Diseases
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation.
Muscular Diseases
Hsp27 suppresses the formation of inclusion bodies induced by expression of R120G alpha B-crystallin, a cause of desmin-related myopathy.
Muscular Diseases
Infantile onset myofibrillar myopathy due to recessive CRYAB mutations.
Muscular Diseases
Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin.
Muscular Diseases
Loss of ?B-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart.
Muscular Diseases
Modeling human protein aggregation cardiomyopathy using murine induced pluripotent stem cells.
Muscular Diseases
Myopathy in Marinesco-Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology.
Muscular Diseases
Myopathy-associated alphaB-crystallin mutants: abnormal phosphorylation, intracellular location, and interactions with other small heat shock proteins.
Muscular Diseases
The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility.
Muscular Diseases
The Paradoxical Effect of PARP Inhibitor BGP-15 on Irinotecan-Induced Cachexia and Skeletal Muscle Dysfunction.
Muscular Diseases
Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.
Muscular Diseases
Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function.
Muscular Diseases
VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
Muscular Disorders, Atrophic
Hsp70 prevents disuse muscle atrophy in senescent rats.
Muscular Dystrophies
A dual role for HSP90 and HSP70 in the inflammatory myopathies: from muscle fiber protection to active invasion by macrophages.
Muscular Dystrophies
A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90.
Muscular Dystrophies
Chaperoning heat shock proteins: Proteomic analysis and relevance for normal and dystrophin-deficient muscle.
Muscular Dystrophies
Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.
Muscular Dystrophies
Therapeutic potential of heat shock protein induction for muscular dystrophy and other muscle wasting conditions.
Muscular Dystrophies, Limb-Girdle
Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.
Muscular Dystrophies, Limb-Girdle
Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D.
Muscular Dystrophies, Limb-Girdle
Myopathy-causing Mutations in an HSP40 Chaperone Disrupt Processing of Specific Client Conformers.
Muscular Dystrophy, Duchenne
Heat shock protein families 70 and 90 in Duchenne muscular dystrophy and inflammatory myopathy: Balancing muscle protection and destruction.
Myalgia
Leucine-Enriched Essential Amino Acids Improve Recovery from Post-Exercise Muscle Damage Independent of Increases in Integrated Myofibrillar Protein Synthesis in Young Men.
Myasthenia Gravis
Autoimmunity to endoplasmic reticulum chaperone GRP94 in myasthenia gravis.
Myasthenia Gravis
Heat shock protein 90? in thymic epithelial tumors and non-thymomatous myasthenia gravis.
Myasthenia Gravis
Hsp60 and AChR cross-reactivity in myasthenia gravis: An update.
Myasthenia Gravis
Increased skeletal muscle expression of the endoplasmic reticulum chaperone GRP78 in patients with myasthenia gravis.
Myasthenia Gravis
The mechanism of acetylcholine receptor in binding MuSK in myasthenia gravis and the role of HSP90 molecular chaperone.
Myasthenia Gravis
The Molecular Anatomy of Human Hsp60 and its Similarity with that of Bacterial Orthologs and Acetylcholine Receptor Reveal a Potential Pathogenetic Role of Anti-Chaperonin Immunity in Myasthenia Gravis.
Myasthenia Gravis
[Expression of heat shock protein 90 in peripheral blood mononuclear cells of children with myasthenia gravis]
Mycetoma
Streptomyces albus isolated from a human actinomycetoma and characterized by molecular techniques.
Mycoses
A CRISPR Interference Platform for Efficient Genetic Repression in Candida albicans.
Mycoses
Effect of stress on heat shock protein levels, immune response and survival to fungal infection of Mamestra brassicae larvae.
Mycoses
Fungal heat-shock proteins in human disease.
Mycoses
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.
Mycoses
Heat Shock Protein 60, Insights to Its Importance in Histoplasma capsulatum: From Biofilm Formation to Host-Interaction.
Mycoses
Heat shock protein inhibitors for the treatment of fungal infections.
Mycoses
Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.
Mycoses
Inhibition of heat-shock protein 90 enhances the susceptibility to antifungals and reduces the virulence of Cryptococcus neoformans/Cryptococcus gattii species complex.
Mycoses
Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress.
Mycoses
PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90.
Mycoses
Progress and prospects for targeting Hsp90 to treat fungal infections.
Mycoses
The Hsp90 Chaperone Network Modulates Candida Virulence Traits.
Mycoses
The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance.
Mycoses
The role of antibodies against hsp90 in the treatment of fungal infections.
Mycoses
The role of hsp90 in fungal infection.
Mycosis Fungoides
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Myelodysplastic Syndromes
BIIB021, an Hsp90 inhibitor, effectively kills a myelodysplastic syndrome cell line via the activation of caspases and inhibition of PI3K/Akt and NF-?B pathway proteins.
Myelodysplastic Syndromes
Expression and prognostic significance of heat-shock proteins in myelodysplastic syndromes.
Myelodysplastic Syndromes
Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase.
Myelodysplastic Syndromes
Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly.
Myelodysplastic Syndromes
Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells.
Myocardial Infarction
Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes.
Myocardial Infarction
alphaB-crystallin is phosphorylated during myocardial infarction: involvement of platelet-derived growth factor-BB.
Myocardial Infarction
An Aggregate Biomarker Risk Score Predicts High Risk of Near-Term Myocardial Infarction and Death: Findings From BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes).
Myocardial Infarction
Analysis of the association of a heat shock protein70-1 gene promoter polymorphism with myocardial infarction and coronary risk traits.
Myocardial Infarction
Antibody response to the 60-kDa heat-shock protein of Chlamydia pneumoniae in patients with coronary artery disease.
Myocardial Infarction
Association between plasma levels of heat shock protein 60 and cardiovascular disease in patients with diabetes mellitus.
Myocardial Infarction
Atherosclerosis as a paradigmatic disease of the elderly: role of the immune system.
Myocardial Infarction
Changes in Hsp60 level of the failing heart following acute myocardial infarction and the effect of long-term treatment with trandolapril.
Myocardial Infarction
Characterization of heat shock protein 27 in extracellular vesicles: a potential anti-inflammatory therapy.
Myocardial Infarction
Contractile function of rat myocardium is less susceptible to hypoxia/reoxygenation after acute infarction.
Myocardial Infarction
Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction.
Myocardial Infarction
Drugs, gene transfer, signaling factors: a bench to bedside approach to myocardial stem cell therapy.
Myocardial Infarction
Effects of 17-AAG on the RIP1/RIP3/MLKL pathway during the development of heart failure following myocardial infarction in rats.
Myocardial Infarction
Effects of heme oxygenase-1 upregulation on isoproterenol-induced myocardial infarction.
Myocardial Infarction
Elevated antibody levels against Chlamydia pneumoniae, human HSP60 and mycobacterial HSP65 are independent risk factors in myocardial infarction and ischaemic heart disease.
Myocardial Infarction
Elevated circulating levels of heat shock protein 70 are related to systemic inflammatory reaction through monocyte Toll signal in patients with heart failure after acute myocardial infarction.
Myocardial Infarction
Elevated heat shock protein 60 levels are associated with higher risk of coronary heart disease in Chinese.
Myocardial Infarction
Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126.
Myocardial Infarction
Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Myocardial Infarction
Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.
Myocardial Infarction
Heat shock protein 27 protects the heart against myocardial infarction.
Myocardial Infarction
Heat Shock Protein 47 (HSP47) Antisense Oligonucleotides Reduce Cardiac Remodeling and Improve Cardiac Function in a Rat Model of Myocardial Infarction.
Myocardial Infarction
Heat shock protein A12B gene therapy improves perfusion, promotes neovascularization, and decreases fibrosis in a murine model of hind limb ischemia.
Myocardial Infarction
Heat-shock protein 90 modulates cardiac ventricular hypertrophy via activation of MAPK pathway.
Myocardial Infarction
HSP20-mediated cardiomyocyte exosomes improve cardiac function in mice with myocardial infarction by activating Akt signaling pathway.
Myocardial Infarction
Hsp60 and heme oxygenase-1 (Hsp32) in acute myocardial infarction.
Myocardial Infarction
Immune-mediated mechanisms of endothelial damage in atherosclerosis.
Myocardial Infarction
Implications of antibodies to heat-shock proteins in ischemic heart disease.
Myocardial Infarction
Induction of heat shock protein 72 in the failing heart is attenuated after an exposure to heat shock.
Myocardial Infarction
Injectable microsphere/hydrogel hybrid system containing heat shock protein as therapy in a murine myocardial infarction model.
Myocardial Infarction
Involvement of HSP90 in ischemic postconditioning-induced cardioprotection by inhibition of the complement system, JNK and inflammation.
Myocardial Infarction
Lipopolysaccharide pretreatment attenuates myocardial infarct size: A possible mechanism involving heat shock protein 70-inhibitory kappaBalpha complex and attenuation of nuclear factor kappaB.
Myocardial Infarction
Low-dose sevoflurane inhalation enhances late cardioprotection from the anti-ulcer drug geranylgeranylacetone.
Myocardial Infarction
Morphine Reduces Myocardial Infarct Size via Heat Shock Protein 90 in Rodents.
Myocardial Infarction
Myocardial injury leads to a release of heat shock protein (hsp) 60 and a suppression of the anti-hsp65 immune response.
Myocardial Infarction
Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction.
Myocardial Infarction
Oral bimoclomol elevates heat shock protein 70 and reduces myocardial infarct size in rats.
Myocardial Infarction
Oral pretreatment with ebselen enhances heat shock protein 72 expression and reduces myocardial infarct size.
Myocardial Infarction
Pathway-Specific Aggregate Biomarker Risk Score Is Associated With Burden of Coronary Artery Disease and Predicts Near-Term Risk of Myocardial Infarction and Death.
Myocardial Infarction
Pharmacological postconditioning with atorvastatin calcium attenuates myocardial ischemia/reperfusion injury in diabetic rats by phosphorylating GSK3?.
Myocardial Infarction
Possible involvement of phosphorylated heat-shock factor-1 in changes in heat shock protein 72 induction in the failing rat heart following myocardial infarction.
Myocardial Infarction
Protective effect of geranylgeranylacetone via enhanced induction of HSPB1 and HSPB8 in mitochondria of the failing heart following myocardial infarction in rats.
Myocardial Infarction
Recombinant human erythropoietin pretreatment attenuates myocardial infarct size: a possible mechanism involves heat shock Protein 70 and attenuation of nuclear factor-kappaB.
Myocardial Infarction
Regional distribution of HSP70 proteins after myocardial infarction.
Myocardial Infarction
Regulation of A-Kinase-Anchoring Protein 12 by Heat Shock Protein A12B to Prevent Ventricular Dysfunction Following Acute Myocardial Infarction in Diabetic Rats.
Myocardial Infarction
Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning.
Myocardial Infarction
Targeted Delivery of Recombinant Heat Shock Protein 27 to Cardiomyocytes Promotes Recovery from Myocardial Infarction.
Myocardial Infarction
Transforming growth factor-?-activated kinase 1 enhances H2O2-induced apoptosis independently of reactive oxygen species in cardiomyocytes.
Myocardial Infarction
[The significance of the changes in expressions of heat shock protein 70 and hemeoxygenase-1 in the myocardium in patients died suddenly due to acute myocardial infarction]
Myocardial Ischemia
Acute Chlamydia pneumoniae infection with heat-shock-protein-60-related response in patients with acute coronary syndrome.
Myocardial Ischemia
Effects of protein transduction domain (PTD) selection and position for improved intracellular delivery of PTD-Hsp27 fusion protein formulations.
Myocardial Ischemia
Heat shock protein 70 protects cardiomyocytes through suppressing SUMOylation and nucleus translocation of phosphorylated eukaryotic elongation factor 2 during myocardial ischemia and reperfusion.
Myocardial Ischemia
Heat shock proteins in myocardial stress.
Myocardial Ischemia
Implications of antibodies to heat-shock proteins in ischemic heart disease.
Myocardial Ischemia
Increased resistance to myocardial ischemia in the Brown Norway vs. Dahl S rat: role of nitric oxide synthase and Hsp90.
Myocardial Ischemia
MAPKAPK-2 modulates p38-MAPK localization and small heat shock protein phosphorylation but does not mediate the injury associated with p38-MAPK activation during myocardial ischemia.
Myocardial Ischemia
Myocardial heat shock gene expression in pigs is dependent on superoxide anion generated at reperfusion.
Myocardial Ischemia
Myocardial injury leads to a release of heat shock protein (hsp) 60 and a suppression of the anti-hsp65 immune response.
Myocardial Ischemia
Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4.
Myocardial Ischemia
Myocardial TLR4 is a determinant of neutrophil infiltration after global myocardial ischemia: mediating KC and MCP-1 expression induced by extracellular HSC70.
Myocardial Ischemia
Nitric oxide induces heat shock protein 72 production and delayed protection against myocardial ischemia in rabbits via activating protein kinase C.
Myocardial Ischemia
Prolongation and enhancement of the anti-apoptotic effects of PTD-Hsp27 fusion proteins using an injectable thermo-reversible gel in a rat myocardial infarction model.
Myocardial Ischemia
Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia.
Myocardial Reperfusion Injury
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.
Myocarditis
Endoplasmic Reticulum Stress Aggravates Viral Myocarditis by Raising Inflammation Through the IRE1-Associated NF-?B Pathway.
Myocarditis
Heat stress aggravates viral myocarditis in mice.
Myocarditis
[Effect of total flavonoids of astragalus on endoplasmic reticulum chaperone, calumenin and connecxin 43 in suckling mouse myocardium with myocarditis caused by coxsackievirus B3].
Myocarditis
[Effects of total flavonids of astragalus on arrhythmia,endoplasmic reticulum stress in mice with viral myocarditis].
Myoma
Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy.
Myoma
Expression of the 60 kDa heat shock protein in peritoneal fluids from women with endometriosis: implications for endometriosis-associated infertility.
Myopathies, Nemaline
KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination.
Myositis
A dual role for HSP90 and HSP70 in the inflammatory myopathies: from muscle fiber protection to active invasion by macrophages.
Myositis
AlphaB-crystallin immunolocalization yields new insights into inclusion body myositis.
Myositis
Heat shock protein families 70 and 90 in Duchenne muscular dystrophy and inflammatory myopathy: Balancing muscle protection and destruction.
Myositis
Increased skeletal muscle expression of the endoplasmic reticulum chaperone GRP78 in patients with myasthenia gravis.
Myositis
Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation.
Myositis
[Expression of the heat shock protein 70 in inflammatory myopathies]
Myositis, Inclusion Body
A dual role for HSP90 and HSP70 in the inflammatory myopathies: from muscle fiber protection to active invasion by macrophages.
Myositis, Inclusion Body
AlphaB-crystallin immunolocalization yields new insights into inclusion body myositis.
Myotonia
Endoplasmic reticulum stress in myotonic dystrophy type 1 muscle.
Myotonic Dystrophy
HspB2/myotonic dystrophy protein kinase binding protein (MKBP) as a novel molecular chaperone: structural and functional aspects.
Myotonic Dystrophy
MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase.
Myotonic Dystrophy
Regulation of the mouse alfaB-crystallin and MKBP/HspB2 promoter activities by shared and gene specific intergenic elements: the importance of context dependency.
Myotonic Dystrophy
The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins.
Myotonic Dystrophy
Transient up-regulation of myotonic dystrophy protein kinase-binding protein, MKBP, and HSP27 in the neonatal myocardium.
Myxedema
Methimazole and propylthiouracil inhibit the oxygen free radical-induced expression of a 72 kilodalton heat shock protein in Graves' retroocular fibroblasts.
nadh:ubiquinone reductase (h+-translocating) deficiency
FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy.
Nasopharyngeal Carcinoma
A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation.
Nasopharyngeal Carcinoma
Clinical and biological significances of heat shock protein 90 (Hsp90) in human nasopharyngeal carcinoma cells and anti-cancer effects of Hsp90 inhibitor.
Nasopharyngeal Carcinoma
Elevated HSP90 associates with expression of HIF-1? and p-AKT and is predictive of poor prognosis in nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Expression of heat shock protein 70 in nasopharyngeal carcinomas: different expression patterns correlate with distinct clinical prognosis.
Nasopharyngeal Carcinoma
FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition.
Nasopharyngeal Carcinoma
Genetic association of promoter in GRP78 gene with nasopharyngeal carcinoma in a Chinese population.
Nasopharyngeal Carcinoma
Heat Shock Protein 90? Provides an Effective and Novel Diagnosis Strategy for Nasopharyngeal Carcinoma.
Nasopharyngeal Carcinoma
Identification of heat shock protein 27 as a radioresistance-related protein in nasopharyngeal carcinoma cells.
Nasopharyngeal Carcinoma
Increased expression of heat shock protein (HSP) 10 and HSP70 correlates with poor prognosis of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Intracell Heat Shock Protein 70 Expression and Nasopharyngeal Carcinoma Stage.
Nasopharyngeal Carcinoma
miR?495 enhances the efficacy of radiotherapy by targeting GRP78 to regulate EMT in nasopharyngeal carcinoma cells.
Nasopharyngeal Carcinoma
Modulatory effects of tumor-derived heat shock protein in DNA vaccination against nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Polymorphism of the stress protein HSP70-2 gene is associated with the susceptibility to the nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
Recombinant adeno-associated virus encoding Epstein-Barr virus latent membrane proteins fused with heat shock protein as a potential vaccine for nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
[Autophagy inhibitor 3-methyladenine enhances the sensitivity of nasopharyngeal carcinoma cells to chemotherapy and radiotherapy].
Nasopharyngeal Carcinoma
[Construction of mammalian co-expression plasmid pIRES -LMP1-HSP90 beta and its expression in vitro]
Nasopharyngeal Carcinoma
[Correlation of heat shock protein 70 expression in nasopharyngeal carcinoma to immunoglobin A against viral capsid antigen of Epstein-Barr virus in sera and its clinical significance]
Nasopharyngeal Carcinoma
[Expression of main heat stress proteins and p53 in nasopharyngeal carcinoma]
Nasopharyngeal Neoplasms
Co-Inhibition of HSP70/HSP90 Synergistically Sensitizes Nasopharyngeal Carcinoma Cells to Thermotherapy.
Nasopharyngeal Neoplasms
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Nematode Infections
Hsp90 Inhibitors in Parasitic Nematodes: Prospects and Challenges.
Neoplasm Metastasis
?7 helix region of ?I domain is crucial for integrin binding to endoplasmic reticulum chaperone gp96: a potential therapeutic target for cancer metastasis.
Neoplasm Metastasis
?B-crystallin Expression in Breast Cancer is Associated with Brain Metastasis.
Neoplasm Metastasis
A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization during Tumor Growth and Metastasis.
Neoplasm Metastasis
A new tumor-specific variant of GRP78 as target for antibody-based therapy.
Neoplasm Metastasis
A secreted Heat shock protein 90 of Trichomonas vaginalis.
Neoplasm Metastasis
A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion.
Neoplasm Metastasis
Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules.
Neoplasm Metastasis
Alkaloid derivative ION-31a inhibits breast cancer metastasis and angiogenesis by targeting HSP90?.
Neoplasm Metastasis
Analysis of polypeptide expression in benign and malignant human breast lesions.
Neoplasm Metastasis
Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer.
Neoplasm Metastasis
Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer.
Neoplasm Metastasis
Association of mortalin (HSPA9) with liver cancer metastasis and prediction for early tumor recurrence.
Neoplasm Metastasis
Autoantibodies against glucose-regulated protein 78 as serological biomarkers in metastatic and recurrent hepatocellular carcinoma.
Neoplasm Metastasis
Bacterial production and functional characterization of the Fab fragment of the murine IgG1/lambda monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics.
Neoplasm Metastasis
Bag-3 expression is involved in pathogenesis and progression of colorectal carcinomas.
Neoplasm Metastasis
BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion.
Neoplasm Metastasis
Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis.
Neoplasm Metastasis
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Neoplasm Metastasis
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Neoplasm Metastasis
Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression.
Neoplasm Metastasis
Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone.
Neoplasm Metastasis
C-terminal HSP90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Neoplasm Metastasis
Can breast cancer Hsp 27 (Heat Shock Protein 27000) expression influence axillary lymph node status?
Neoplasm Metastasis
Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity.
Neoplasm Metastasis
Characterization and prognostic significance of mortalin, Bcl-2 and Bax in intrahepatic cholangiocarcinoma.
Neoplasm Metastasis
Chemotherapy Controls Metastasis Through Stimulatory Effects on GRP78 and Its Transcription Factor CREB3L1.
Neoplasm Metastasis
CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer.
Neoplasm Metastasis
Clinical development of 17-allylamino, 17-demethoxygeldanamycin.
Neoplasm Metastasis
Clinical Implications of HSC70 Expression in Clear Cell Renal Cell Carcinoma.
Neoplasm Metastasis
Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity.
Neoplasm Metastasis
Comparison of the expression of 5 heat shock proteins in benign and malignant salivary gland tumor tissues.
Neoplasm Metastasis
Concomitant high expression of ER?36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior.
Neoplasm Metastasis
CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer.
Neoplasm Metastasis
Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1.
Neoplasm Metastasis
Curcumin suppresses proliferation and invasion in non-small cell lung cancer by modulation of MTA1-mediated Wnt/?-catenin pathway.
Neoplasm Metastasis
De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells.
Neoplasm Metastasis
Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan.
Neoplasm Metastasis
Design and synthesis of pyrimidinyl acyl thioureas as novel Hsp90 inhibitors in invasive ductal breast cancer and its bone metastasis.
Neoplasm Metastasis
Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis.
Neoplasm Metastasis
Diagnostic, clinicopathologic, therapeutic and prognostic value of Plasma Heat Shock Protein 90 levels in patients with advanced Gastrointestinal Carcinoma.
Neoplasm Metastasis
Different expression of CD44, ICAM-1, and HSP60 on primary tumor and metastases of a human pancreatic carcinoma growing in scid mice.
Neoplasm Metastasis
Down-Regulated Expression of HSP70 in Correlation with Clinicopathology of Cholangiocarcinoma.
Neoplasm Metastasis
Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers.
Neoplasm Metastasis
Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models.
Neoplasm Metastasis
Effect of hypoxia on the expression of alphaB-crystallin in head and neck squamous cell carcinoma.
Neoplasm Metastasis
Effects of Hsp90 inhibition in neuroblastoma: analysis of drug sensitivity, target modulation and the influence of bone marrow microenvironment.
Neoplasm Metastasis
Elevated HSP90 associates with expression of HIF-1? and p-AKT and is predictive of poor prognosis in nasopharyngeal carcinoma.
Neoplasm Metastasis
Elevated levels of mortalin expression in human brain tumors.
Neoplasm Metastasis
Elevated Mortalin correlates with poor outcome in hepatocellular carcinoma.
Neoplasm Metastasis
Elucidation of antiangiogenic potential of Vitexin obtained from Cucumis sativus targeting Hsp90 protein: A novel multipathway targeted approach to restrain angiogenic phenomena.
Neoplasm Metastasis
Emerging Roles of Extracellular Hsp90 in Cancer.
Neoplasm Metastasis
Endoplasmic reticulum chaperone glucose-regulated protein 78 in gastric cancer: An emerging biomarker.
Neoplasm Metastasis
Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport.
Neoplasm Metastasis
Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Neoplasm Metastasis
Erythroid Differentiation Regulator 1, an Interleukin 18-Regulated Gene, Acts as a Metastasis Suppressor in Melanoma.
Neoplasm Metastasis
Estrogen receptor-?36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
Neoplasm Metastasis
Expression and significance of glucose-regulated protein 78 in human osteosarcoma.
Neoplasm Metastasis
Expression of glucose regulated protein 78 (GRP78) determines colorectal cancer response to chemotherapy.
Neoplasm Metastasis
Expression of glucose-regulated protein 78 as prognostic biomarkers for triple-negative breast cancer.
Neoplasm Metastasis
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma.
Neoplasm Metastasis
Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer.
Neoplasm Metastasis
Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study.
Neoplasm Metastasis
Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules.
Neoplasm Metastasis
Expression of major heat shock proteins in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy.
Neoplasm Metastasis
Expression of the CD117, COX-2 and HSP90 antigens and cell proliferation in fine-needle-aspirated cells from metastatic melanomas.
Neoplasm Metastasis
Expression of the heat shock cognate protein HSP73 correlates with tumour thickness of primary melanomas and is enhanced in melanoma metastases.
Neoplasm Metastasis
Expression pattern of heat shock protein 90 in patients with oral squamous cell carcinoma in northern Taiwan.
Neoplasm Metastasis
Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer.
Neoplasm Metastasis
Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis.
Neoplasm Metastasis
Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells.
Neoplasm Metastasis
Extracellular HSP70/HSP70-PCs regulate hepatocarcinoma cell migration and invasion via RhoA.
Neoplasm Metastasis
Extracellular Hsp90 (eHsp90) as the Actual Target in Clinical Trials: Intentionally or Unintentionally.
Neoplasm Metastasis
Extracellular Hsp90 and TGF? regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model.
Neoplasm Metastasis
Extracellular HSP90: conquering the cell surface.
Neoplasm Metastasis
Extracellular Hsp90? and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.
Neoplasm Metastasis
FOXP2 promotes tumor proliferation and metastasis by targeting GRP78 in triple-negative breast cancer.
Neoplasm Metastasis
FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.
Neoplasm Metastasis
Functional pathways shared by liver and lung metastases: a mitochondrial chaperone machine is up-regulated in soft-tissue breast cancer metastasis.
Neoplasm Metastasis
GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78.
Neoplasm Metastasis
Geldanamycin and its derivatives as Hsp90 inhibitors.
Neoplasm Metastasis
Gene expression profile of renal cell carcinoma clear cell type.
Neoplasm Metastasis
Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.
Neoplasm Metastasis
Glucose regulated protein 78: A critical link between tumor microenvironment and cancer hallmarks.
Neoplasm Metastasis
Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway.
Neoplasm Metastasis
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.
Neoplasm Metastasis
GRP75-mediated upregulation of HMGA1 stimulates stage I lung adenocarcinoma progression by activating JNK/c-JUN signaling.
Neoplasm Metastasis
GRP78 activates the Wnt/HOXB9 pathway to promote invasion and metastasis of hepatocellular carcinoma by chaperoning LRP6.
Neoplasm Metastasis
GRP78 and GAL3, differentially regulated by lymph node homogenates, as potential biomarkers for lymph node metastasis in mouse hepatocellular carcinoma cells.
Neoplasm Metastasis
GRP78 enabled micelle-based glioma targeted drug delivery.
Neoplasm Metastasis
GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma.
Neoplasm Metastasis
GRP78 induction in cancer: therapeutic and prognostic implications.
Neoplasm Metastasis
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Neoplasm Metastasis
GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy.
Neoplasm Metastasis
HDAC6: Physiological function and its selective inhibitors for cancer treatment.
Neoplasm Metastasis
Heat Shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF.
Neoplasm Metastasis
Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma.
Neoplasm Metastasis
Heat shock protein 27 overexpression in breast cancer lymph node metastasis.
Neoplasm Metastasis
Heat shock protein 27: a potential biomarker of peritoneal metastasis in epithelial ovarian cancer?
Neoplasm Metastasis
Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer.
Neoplasm Metastasis
Heat shock protein 70 downregulation inhibits proliferation, migration and tumorigenicity in hepatocellular carcinoma cells.
Neoplasm Metastasis
Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma.
Neoplasm Metastasis
Heat shock protein B6 potently increases non-small cell lung cancer growth.
Neoplasm Metastasis
Heat shock protein expression in canine malignant mammary tumours.
Neoplasm Metastasis
Heat Shock Protein-Peptide and HSP-Based Immunotherapies for the Treatment of Cancer.
Neoplasm Metastasis
Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?
Neoplasm Metastasis
Heat shock protein 90 as a molecular target for therapy in oral squamous cell carcinoma: Inhibitory effects of 17?DMAG and ganetespib on tumor cells.
Neoplasm Metastasis
Heat-shock protein 90 (Hsp90) as a molecular target for therapy of gastrointestinal cancer.
Neoplasm Metastasis
Heat-shock protein 90 inhibitors as antitumor agents: a survey of the literature from 2005 to 2010.
Neoplasm Metastasis
Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2.
Neoplasm Metastasis
High expression of glucose-regulated protein 78 (GRP78) is associated with metastasis and poor prognosis in patients with esophageal squamous cell carcinoma.
Neoplasm Metastasis
High Expression of GRP78 Promotes Invasion and Metastases in Patients with Esophageal Squamous Cell Carcinoma.
Neoplasm Metastasis
High expression of heat shock protein 90 is associated with tumor aggressiveness and poor prognosis in patients with advanced gastric cancer.
Neoplasm Metastasis
High Levels of Hsp90 Cochaperone p23 Promote Tumor Progression and Poor Prognosis in Breast Cancer by Increasing Lymph Node Metastases and Drug Resistance.
Neoplasm Metastasis
Histone deacetylase 6 in cancer.
Neoplasm Metastasis
HN1L promotes migration and invasion of breast cancer by up-regulating the expression of HMGB1.
Neoplasm Metastasis
HSP20 Exerts a Protective Effect on Preeclampsia by Regulating Function of Trophoblast Cells Via Akt Pathways.
Neoplasm Metastasis
HSP27 expression levels are associated with the sensitivity of hepatocellular carcinoma cells to 17-allylamino-17-demethoxygeldanamycin.
Neoplasm Metastasis
HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling.
Neoplasm Metastasis
HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment.
Neoplasm Metastasis
HSP70 promotes tumor progression by stabilizing Skp2 expression in gastric cancer cells.
Neoplasm Metastasis
HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma.
Neoplasm Metastasis
HSP90 and HSP70 are essential for stabilization and activation of the WASF3 metastasis promoting protein.
Neoplasm Metastasis
HSP90 as a new therapeutic target for cancer therapy: the story unfolds.
Neoplasm Metastasis
Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells.
Neoplasm Metastasis
Hsp90 C-Terminal Inhibitors Exhibit Antimigratory Activity by Disrupting the Hsp90?/Aha1 Complex in PC3-MM2 Cells.
Neoplasm Metastasis
HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.
Neoplasm Metastasis
Hsp90 is an essential regulator of EphA2 receptor stability and signaling: implications for cancer cell migration and metastasis.
Neoplasm Metastasis
Hsp90 phosphorylation, Wee1, and the cell cycle.
Neoplasm Metastasis
Hsp90: a novel target for the disruption of multiple signaling cascades.
Neoplasm Metastasis
Hypoxia Enhances Lysophosphatidic Acid Responsiveness in Ovarian Cancer Cells and Lysophosphatidic Acid Induces Ovarian Tumor Metastasis In vivo.
Neoplasm Metastasis
Identification and Comparison of Differentiation-Related Proteins in Hepatocellular Carcinoma Tissues by Proteomics.
Neoplasm Metastasis
Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry.
Neoplasm Metastasis
Identification of heat shock protein 90? as an IMH-2 epitope-associated protein and correlation of its mRNA overexpression with colorectal cancer metastasis and poor prognosis.
Neoplasm Metastasis
Identification of the Transmembrane Glucose Regulated Protein 78 as a Biomarker for the Brain Cancer Glioblastoma Multiforme by Gene Expression and Proteomic Studies.
Neoplasm Metastasis
IGFBP2 plays an important role in heat shock protein 27-mediated cancer progression and metastasis.
Neoplasm Metastasis
Immunohistochemical expression of Hsp60 correlates with tumor progression and hormone resistance in prostate cancer.
Neoplasm Metastasis
Immunotherapy of radioresistant mammary tumors with early metastasis using molecular chaperone vaccines combined with ionizing radiation.
Neoplasm Metastasis
Impact of heat-shock protein 90 on cancer metastasis.
Neoplasm Metastasis
In silico screening and exploration into phenotypic alterations of deleterious oncogenic single nucleotide polymorphisms in HSPB1 gene.
Neoplasm Metastasis
Increased expression of heat shock protein 27 correlates with peritoneal metastasis in epithelial ovarian cancer.
Neoplasm Metastasis
Indolylkojyl methane analogue IKM5 potentially inhibits invasion of breast cancer cells via attenuation of GRP78.
Neoplasm Metastasis
Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors.
Neoplasm Metastasis
Inducible HSP70 antagonizes cisplatin?induced cell apoptosis through inhibition of the MAPK signaling pathway in HGC?27 cells.
Neoplasm Metastasis
Induction of heat shock protein 27 by hydroxyurea and its relationship to experimental metastasis.
Neoplasm Metastasis
Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases.
Neoplasm Metastasis
Inhibition of Cancer Invasion and Metastasis by Targeting the Molecular Chaperone Heat-shock Protein 90.
Neoplasm Metastasis
Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface Associated GRP78.
Neoplasm Metastasis
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Neoplasm Metastasis
Interaction between HSP60 and {beta}-catenin promotes metastasis.
Neoplasm Metastasis
Is co-expression of USP22 and HSP90 more effective in predicting prognosis of gastric cancer?
Neoplasm Metastasis
iTRAQ Quantitative Proteomic Comparison of Metastatic and Non-Metastatic Uveal Melanoma Tumors.
Neoplasm Metastasis
Knockdown of lncRNA ZNRD1-AS1 suppresses gastric cancer cell proliferation and metastasis by targeting the miR-9-5p/HSP90AA1 axis.
Neoplasm Metastasis
Long noncoding RNA DANCR promotes colorectal cancer proliferation and metastasis via miR-577 sponging.
Neoplasm Metastasis
Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells.
Neoplasm Metastasis
Low dose HSP90 inhibition with AUY922 blunts rapid evolution of metastatic and drug resistant phenotypes induced by TGF-? and paclitaxel in A549 cells.
Neoplasm Metastasis
Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue.
Neoplasm Metastasis
MDA-9 and GRP78 as potential diagnostic biomarkers for early detection of melanoma metastasis.
Neoplasm Metastasis
Megakaryocytes mediate hyperglycemia-induced tumor metastasis.
Neoplasm Metastasis
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells.
Neoplasm Metastasis
Metastasis and the Tumor Microenvironment: A Joint Metastasis Research Society-AACR Conference - Research on Metastasis: Part 2.
Neoplasm Metastasis
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Neoplasm Metastasis
Microvessel density, expression of proto-oncogenes, resistance-related proteins and incidence of metastases in primary ovarian carcinomas.
Neoplasm Metastasis
Mitochondrial chaperone, TRAP1 modulates mitochondrial dynamics and promotes tumor metastasis.
Neoplasm Metastasis
Molecular chaperones as regulators of cell death.
Neoplasm Metastasis
Molecular characterization of hsp90 isoforms in colorectal cancer cells and its association with tumour progression.
Neoplasm Metastasis
Molecular mechanism and targeted therapy of Hsp90 involved in lung cancer: New discoveries and developments (Review).
Neoplasm Metastasis
Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis.
Neoplasm Metastasis
Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits.
Neoplasm Metastasis
Monoclonal Antibody against Cell Surface GRP78 as a Novel Agent in Suppressing PI3K/AKT Signaling, Tumor Growth and Metastasis.
Neoplasm Metastasis
Mortalin expression in pancreatic cancer and its clinical and prognostic significance.
Neoplasm Metastasis
Mortalin overexpression predicts poor prognosis in early stage of non-small cell lung cancer.
Neoplasm Metastasis
Mortalin promotes breast cancer malignancy.
Neoplasm Metastasis
Mortalin promotes cell proliferation and epithelial mesenchymal transition of intrahepatic cholangiocarcinoma cells in vitro.
Neoplasm Metastasis
Mortaparib, a novel dual inhibitor of mortalin and PARP1, is a potential drug candidate for ovarian and cervical cancers.
Neoplasm Metastasis
N,N'-dinitrosopiperazine--mediated heat-shock protein 70-2 expression is involved in metastasis of nasopharyngeal carcinoma.
Neoplasm Metastasis
Nanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78.
Neoplasm Metastasis
Nck-associated protein 1 associates with HSP90 to drive metastasis in human non-small-cell lung cancer.
Neoplasm Metastasis
Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-?-catenin signaling in breast cancer.
Neoplasm Metastasis
New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.
Neoplasm Metastasis
New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90.
Neoplasm Metastasis
NHF-derived carbon dots: prevalidation approach in breast cancer treatment.
Neoplasm Metastasis
NMS-E973, a novel synthetic inhibitor of Hsp90 with activity against multiple models of drug resistance to targeted agents, including intracranial metastases.
Neoplasm Metastasis
Novel C-terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self-renewal, and epithelial-mesenchymal transition.
Neoplasm Metastasis
Novel serum markers HSP60, CHI3L1, and IGFBP-2 in metastatic colorectal cancer.
Neoplasm Metastasis
Nuclear Accumulation of Heat-shock Protein 90 Is Associated with Poor Survival and Metastasis in Patients with Non-small Cell Lung Cancer.
Neoplasm Metastasis
Nuclear heat shock protein 110 expression is associated with poor prognosis and hyperthermo-chemotherapy resistance in gastric cancer patients with peritoneal metastasis.
Neoplasm Metastasis
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
Neoplasm Metastasis
NZ28-induced inhibition of HSF1, SP1 and NF-?B triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells.
Neoplasm Metastasis
ORAOV1-B Promotes OSCC Metastasis via the NF-?B-TNF? Loop.
Neoplasm Metastasis
Organ-specific efficacy of HSP90 inhibitor in multiple-organ metastasis model of chemorefractory small cell lung cancer.
Neoplasm Metastasis
Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-?/Smad2/3 signaling.
Neoplasm Metastasis
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
Neoplasm Metastasis
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Neoplasm Metastasis
Overexpression of Mortalin in hepatocellular carcinoma and its relationship with angiogenesis and epithelial to mesenchymal transition.
Neoplasm Metastasis
Patterns of heat shock protein (HSP70) expression and Kupffer cell activity following thermal ablation of liver and colorectal liver metastases.
Neoplasm Metastasis
Plasma levels of heat shock protein 90 alpha associated with lung cancer development and treatment responses.
Neoplasm Metastasis
PLC?1-PKC? signaling-mediated Hsp90? plasma membrane translocation facilitates tumor metastasis.
Neoplasm Metastasis
PNSA, a Novel C-Terminal Inhibitor of HSP90, Reverses Epithelial-Mesenchymal Transition and Suppresses Metastasis of Breast Cancer Cells In Vitro.
Neoplasm Metastasis
Preoperative heat shock protein 47 levels identify colorectal cancer patients with lymph node metastasis and poor prognosis.
Neoplasm Metastasis
Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.
Neoplasm Metastasis
Proteomics analysis of differential protein expression identifies heat shock protein 47 as a predictive marker for lymph node metastasis in patients with colorectal cancer.
Neoplasm Metastasis
Quantitative score modulation of HSP90 and HSP27 in clear cell renal cell carcinoma.
Neoplasm Metastasis
Relationship between the expression of phosphorylated heat shock protein beta-1 with lymph node metastases of breast cancer.
Neoplasm Metastasis
Retinal toxicity induced by small-molecule Hsp90 inhibitors in beagle dogs.
Neoplasm Metastasis
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
Neoplasm Metastasis
Role of HSP60/HSP10 in Lung Cancer: Simple Biomarkers or Leading Actors?
Neoplasm Metastasis
Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity.
Neoplasm Metastasis
Secreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer.
Neoplasm Metastasis
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.
Neoplasm Metastasis
Serum level of soluble 70-kD heat shock protein is associated with high mortality in patients with colorectal cancer without distant metastasis.
Neoplasm Metastasis
Significance of expression of heat shock protein90alpha in human gastric cancer.
Neoplasm Metastasis
Silencing Heat Shock Protein 27 Inhibits the Progression and Metastasis of Colorectal Cancer (CRC) by Maintaining the Stability of Stromal Interaction Molecule 1 (STIM1) Proteins.
Neoplasm Metastasis
Silencing of Glucose-Regulated Protein 78 (GRP78) Enhances Cell Migration Through the Upregulation of Vimentin in Hepatocellular Carcinoma Cells.
Neoplasm Metastasis
Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159.
Neoplasm Metastasis
SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells.
Neoplasm Metastasis
Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.
Neoplasm Metastasis
Solid-phase immunoassays in mechanism-based drug discovery: their application in the development of inhibitors of the molecular chaperone heat-shock protein 90.
Neoplasm Metastasis
Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis.
Neoplasm Metastasis
Stress protein Hsp27 expression predicts the outcome in operated small cell lung carcinoma and large cell neuroendocrine carcinoma patients.
Neoplasm Metastasis
Survivin-Mediated Cancer Cell Migration Through GRP78 and Epithelial-Mesenchymal Transition (EMT) Marker Expression in Mahlavu Cells.
Neoplasm Metastasis
Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts.
Neoplasm Metastasis
Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo.
Neoplasm Metastasis
Targeting heat shock protein 90 for anti-cancer drug development.
Neoplasm Metastasis
Targeting Hsp90 in Non-Cancerous Maladies.
Neoplasm Metastasis
Targeting the Extracellular HSP90 Co-Chaperone Morgana Inhibits Cancer Cell Migration and Promotes Anticancer Immunity.
Neoplasm Metastasis
Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions.
Neoplasm Metastasis
Targeting the testis-specific heat-shock protein 70-2 (HSP70-2) reduces cellular growth, migration, and invasion in renal cell carcinoma cells.
Neoplasm Metastasis
The 4C5 cell-impermeable anti-HSP90 antibody with anti-cancer activity, is composed of a single light chain dimer.
Neoplasm Metastasis
The antitumor agent PBT-1 directly targets HSP90 and hnRNP A2/B1 and inhibits lung adenocarcinoma growth and metastasis.
Neoplasm Metastasis
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast.
Neoplasm Metastasis
The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis.
Neoplasm Metastasis
The effects of Hsp90 expression alteration on spinal metastases of breast carcinoma.
Neoplasm Metastasis
The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase.
Neoplasm Metastasis
The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line.
Neoplasm Metastasis
The hexameric structures of human heat shock protein 90.
Neoplasm Metastasis
The HIV Protease Inhibitor Nelfinavir Dowregulates RET Signaling and Induces Apoptosis in Medullary Thyroid Cancer Cells.
Neoplasm Metastasis
The matrix metalloproteinase 7 (MMP7) links Hsp90 chaperone with acquired drug resistance and tumor metastasis.
Neoplasm Metastasis
The phosphorylation-specific association of STMN1 with GRP78 promotes breast cancer metastasis.
Neoplasm Metastasis
The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancy.
Neoplasm Metastasis
The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated ?2M.
Neoplasm Metastasis
Therapeutic potency of heat-shock protein-90 pharmacological inhibitors in the treatment of gastrointestinal cancer, current status and perspectives.
Neoplasm Metastasis
Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation.
Neoplasm Metastasis
Transactivation of the epidermal growth factor receptor by heat shock protein 90 via Toll-like receptor 4 contributes to the migration of glioblastoma cells.
Neoplasm Metastasis
Transcriptional repression of the prosurvival endoplasmic reticulum chaperone GRP78/BIP by E2F1.
Neoplasm Metastasis
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.
Neoplasm Metastasis
Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma.
Neoplasm Metastasis
Up-regulation of cathepsin S expression by HSP90 and 5-HT7 receptor-dependent serotonin signaling correlates with triple negativity of human breast cancer.
Neoplasm Metastasis
Upregulated Heat Shock Proteins After Hyperthermic Chemotherapy Point to Induced Cell Survival Mechanisms in Affected Tumor Cells From Peritoneal Carcinomatosis.
Neoplasm Metastasis
Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.
Neoplasm Metastasis
[Association between expressions of HSP70, HSP90 and efficacy of chemotherapy in colorectal cancer patients with unresectable liver metastasis]
Neoplasm Metastasis
[Comparative proteomics of the serum in patients with nasopharyngeal carcinoma: a study with two-dimensional electrophoresis and MALDI-TOF-MS]
Neoplasm Metastasis
[Diagnostic and Therapeutic Potential of Membrane HSP90].
Neoplasm Metastasis
[Expression of GRP78 and GRP94 in the liver tissues and their clinicopathological significance in children with hepatoblastoma].
Neoplasm Metastasis
[The Role of Membrane-Bound Heat Shock Proteins Hsp90 in Migration of Tumor Cells in vitro and Involvement of Cell Surface Heparan Sulfate Proteoglycans in Protein Binding to Plasma Membrane].
Neoplasm Micrometastasis
Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface Associated GRP78.
Neoplasm, Residual
Combined PI3K/Akt and Hsp90 targeting synergistically suppresses essential functions of alloreactive T cells and increases Tregs.
Neoplasm, Residual
GRP78 induction in cancer: therapeutic and prognostic implications.
Neoplasm, Residual
Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in Mice.
Neoplasm, Residual
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
Neoplasm, Residual
Transcatheter arterial embolization combined with radiofrequency ablation activates CD8(+) T-cell infiltration surrounding residual tumors in the rabbit VX2 liver tumors.
Neoplasms
"UPRegulation" of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses.
Neoplasms
(-)- Epigallocatechin-3-gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress.
Neoplasms
(-)-epigallocatechin gallate overcomes resistance to Etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78.
Neoplasms
(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.
Neoplasms
(1)H, (15)N and (13)C backbone resonance assignments of the TPR1 and TPR2A domains of mouse STI1.
Neoplasms
(89)Zr-trastuzumab PET visualises HER2 downregulation by the HSP90 inhibitor NVP-AUY922 in a human tumour xenograft.
Neoplasms
14-3-3sigma, the double-edged sword of human cancers.
Neoplasms
17 AAG for HSP90 inhibition in cancer--from bench to bedside.
Neoplasms
17-(Allylamino)-17-demethoxygeldanamycin activity in human melanoma models.
Neoplasms
17-AAG and Apoptosis, Autophagy, and Mitophagy in Canine Osteosarcoma Cell Lines.
Neoplasms
17-AAG inhibits vemurafenib-associated MAP kinase activation and is synergistic with cellular immunotherapy in a murine melanoma model.
Neoplasms
17-AAG: mechanisms of antitumour activity.
Neoplasms
17-ABAG, a novel geldanamycin derivative, inhibits LNCaP-cell proliferation through heat shock protein 90 inhibition.
Neoplasms
17-Allyamino-17-demethoxygeldanamycin and 17-NN-dimethyl ethylene diamine-geldanamycin have cytotoxic activity against multiple gynecologic cancer cell types.
Neoplasms
17-allylamino-17-demethoxygeldanamycin impeded chemotherapy through antioxidant activation via reducing reactive oxygen species-induced cell death.
Neoplasms
17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts.
Neoplasms
17-Allylamino-17-demethoxygeldanamycin-induced Changes in [(18)F]Fluorothymidine Uptake.
Neoplasms
17-DMAG disrupted the autophagy flux leading to the apoptosis of acute lymphoblastic leukemia cells by inducing heat shock cognate protein 70.
Neoplasms
17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.
Neoplasms
17-DMAG targets the NF-{kappa}B family of proteins to induce apoptosis in CLL: clinical implications of HSP90 inhibition.
Neoplasms
177Lu-octreotate therapy for neuroendocrine tumours is enhanced by Hsp90 inhibition.
Neoplasms
17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells.
Neoplasms
18?-Glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.
Neoplasms
1D Coordination Polymer Nanofibers for Low-Temperature Photothermal Therapy.
Neoplasms
2,4-dihydroxy benzaldehyde derived Schiff bases as small molecule Hsp90 inhibitors: Rational identification of a new anticancer lead.
Neoplasms
2-((1-Phenyl-1H-1,2,3-triazol-4-yl)methyl)-2-azabicyclo[3.2.1]octan-3-one derivatives: Simplification and modification of aconitine scaffold for the discovery of novel anticancer agents.
Neoplasms
2-phenylethynesulfonamide inhibits growth of oral squamous cell carcinoma cells by blocking the function of heat shock protein 70.
Neoplasms
27-Hydroxycholesterol is a specific factor in the neoplastic microenvironment of HCC that causes MDR via GRP75 regulation of the redox balance and metabolic reprogramming.
Neoplasms
2D-PAGE of ovarian cancer: analysis of soluble and insoluble fractions using medium-range immobilized pH gradients.
Neoplasms
3-Arylcoumarin derivatives manifest anti-proliferative activity through Hsp90 inhibition.
Neoplasms
3D-QSAR Assisted Design, Synthesis and Evaluation of Novobiocin Analogues.
Neoplasms
3D-QSAR, molecular docking, and molecular dynamic simulations for prediction of new Hsp90 inhibitors based on isoxazole scaffold.
Neoplasms
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.
Neoplasms
5'-N-ethylcarboxamidoadenosine is not a paralog-specific Hsp90 inhibitor.
Neoplasms
70-kDa heat shock cognate protein interacts directly with the N-terminal region of the retinoblastoma gene product pRb. Identification of a novel region of pRb-mediating protein interaction.
Neoplasms
7Hsp70 serum levels in pet dogs-a potential diagnostic biomarker for spontaneous round cell tumors.
Neoplasms
89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922.
Neoplasms
90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
Neoplasms
?-hCG induced mutant BRCA1 ignites drug resistance in susceptible breast tissue.
Neoplasms
?-Lapachone Induces NQO1- and Oxidative Stress-Dependent Hsp90 Cleavage and Inhibits Tumor Growth and Angiogenesis.
Neoplasms
?7 helix region of ?I domain is crucial for integrin binding to endoplasmic reticulum chaperone gp96: a potential therapeutic target for cancer metastasis.
Neoplasms
?B-Crystallin in clear cell renal cell carcinoma: Tumor progression and prognostic significance.
Neoplasms
?B-Crystallin is a Novel Oncoprotein Associated with Poor Prognosis in Breast Cancer.
Neoplasms
?B-Crystallin regulates expansion of CD11b?Gr-1? immature myeloid cells during tumor progression.
Neoplasms
?B-crystallin: a novel regulator of breast cancer metastasis to the brain.
Neoplasms
?III-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells.
Neoplasms
A 12-mer Peptide of Tag7 (PGLYRP1) Forms a Cytotoxic Complex with Hsp70 and Inhibits TNF-Alpha Induced Cell Death.
Neoplasms
A 14-mer Hsp70 peptide stimulates natural killer (NK) cell activity.
Neoplasms
A 14-mer peptide from HSP70 protein is the critical epitope which enhances NK activity against tumor cells in vivo.
Neoplasms
A 2,5-Dihydroxybenzoic Acid-Gelatin Conjugate Inhibits the Basal and Hsp90-Stimulated Migration and Invasion of Tumor Cells.
Neoplasms
A 2-helix small protein labeled with 68Ga for PET imaging of HER2 expression.
Neoplasms
A bifunctional organometallic ruthenium drug with multiple modes of inducing apoptosis.
Neoplasms
A biochemical rationale for the anticancer effects of Hsp90 inhibitors: slow, tight binding inhibition by geldanamycin and its analogues.
Neoplasms
A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea.
Neoplasms
A case of progressing focal nodular hyperplasia and its molecular expression pattern.
Neoplasms
A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy.
Neoplasms
A chemical compound inhibiting the Aha1-Hsp90 chaperone complex.
Neoplasms
A chemical proteomics approach reveals Hsp27 as a target for proapoptotic clerodane diterpenes.
Neoplasms
A compound that inhibits the HOP-Hsp90 complex formation and has unique killing effects in breast cancer cell lines.
Neoplasms
A computational study on the role of water and conformational fluctuations in Hsp90 in response to inhibitors.
Neoplasms
A CpG oligodeoxynucleotide potentiates the anti-tumor effect of HSP65-Her2 fusion protein against Her2 positive B16 melanoma in mice.
Neoplasms
A cremophor-free formulation for tanespimycin (17-AAG) using PEO-b-PDLLA micelles: Characterization and pharmacokinetics in rats.
Neoplasms
A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization during Tumor Growth and Metastasis.
Neoplasms
A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2.
Neoplasms
A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis.
Neoplasms
A DM1-doped porous gold nanoshell system for NIR accelerated redox-responsive release and triple modal imaging guided photothermal synergistic chemotherapy.
Neoplasms
A Dynamic molecular basis for malfunction in disease mutants of p97/VCP.
Neoplasms
A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies.
Neoplasms
A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy in Vivo.
Neoplasms
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Neoplasms
A group of novel HIF-1? inhibitors, glyceollins, blocks HIF-1? synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
Neoplasms
A heat shock protein 70-based vaccine with enhanced immunogenicity for clinical use.
Neoplasms
A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.
Neoplasms
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors.
Neoplasms
A High-Throughput Screen for Inhibitors of the Hsp90-Chaperone Machine.
Neoplasms
A highly selective Hsp90 affinity chromatography resin with a cleavable linker.
Neoplasms
A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells.
Neoplasms
A hsp70-2 mutation recognized by CTL on a human renal cell carcinoma.
Neoplasms
A hypoxia-induced decrease of either MICA/B or Hsp70 on the membrane of tumor cells mediates immune escape from NK cells.
Neoplasms
A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma.
Neoplasms
A Mortalin/HSPA9-Mediated Switch in Tumor-Suppressive Signaling of Raf/MEK/Extracellular Signal-Regulated Kinase.
Neoplasms
A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer.
Neoplasms
A multimodal imaging-guided nanoreactor for cooperative combination of tumor starvation and multiple mechanism-enhanced mild temperature phototherapy.
Neoplasms
A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice.
Neoplasms
A new approach for enhancing differential selectivity of drugs to cancer cells.
Neoplasms
A new purification method for enhancing the immunogenicity of heat shock protein 70-peptide complexes.
Neoplasms
A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance.
Neoplasms
A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma.
Neoplasms
A new tumor-specific variant of GRP78 as target for antibody-based therapy.
Neoplasms
A non-receptor-mediated mechanism for internalization of molecular chaperones.
Neoplasms
A novel anticancer approach: SEA-anchored tumor cells expressing heat shock protein 70 onto the surface elicit strong anticancer efficacy.
Neoplasms
A Novel Approach to Anticancer Therapy: Molecular Modules Based on the Barnase:Barstar Pair for Targeted Delivery of HSP70 to Tumor Cells.
Neoplasms
A novel C-terminal HSP90 inhibitor KU135 induces apoptosis and cell cycle arrest in melanoma cells.
Neoplasms
A novel C-terminal Hsp90 inhibitor KU758 synergizes efficacy in combination with BRAF or MEK inhibitors and targets drug-resistant pathways in BRAF-mutant melanomas.
Neoplasms
A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response.
Neoplasms
A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells.
Neoplasms
A novel combination treatment for breast cancer cells involving BAPTA-AM and proteasome inhibitor bortezomib.
Neoplasms
A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy.
Neoplasms
A Novel Doxorubicin Prodrug with GRP78 Recognition and Nucleus-Targeting Ability for Safe and Effective Cancer Therapy.
Neoplasms
A Novel Extracellular Hsp90 Mediated Co-Receptor Function for LRP1 Regulates EphA2 Dependent Glioblastoma Cell Invasion.
Neoplasms
A novel heat shock protein 90 inhibitor potently targets adrenocortical carcinoma tumor suppression.
Neoplasms
A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation.
Neoplasms
A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer.
Neoplasms
A novel method to assay molecular chaperone activity of HSP70: evaluation of drug resistance in cancer treatment.
Neoplasms
A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens.
Neoplasms
A novel sulfamethoxazole derivative as an inhibitory agent against HSP70: A combination of computational with in vitro studies.
Neoplasms
A novel temperature-responsive micelle for enhancing combination therapy.
Neoplasms
A novel therapeutic strategy for the treatment of glioma, combining chemical and molecular targeting of hsp90a.
Neoplasms
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
Neoplasms
A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death.
Neoplasms
A Phase 1 Dose-Escalation Study of Irinotecan in Combination with 17-Allylamino-17-Demethoxygeldanamycin in Patients with Solid Tumors.
Neoplasms
A phase 1 study of the heat shock protein 90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft tissue sarcomas.
Neoplasms
A phase 2 clinical trial of the heat shock protein 90 (HSP 90) inhibitor ganetespib in patients with refractory advanced esophagogastric cancer.
Neoplasms
A Phase 2 Study of the Hsp90 Inhibitor AUY922 as Treatment for Patients with Refractory Gastrointestinal Stromal Tumors.
Neoplasms
A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers.
Neoplasms
A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas.
Neoplasms
A Phase I Study of the Heat Shock Protein 90 Inhibitor Alvespimycin (17-DMAG) Given Intravenously to Patients with Advanced Solid Tumors.
Neoplasms
A Phase I Study of the Hsp90 Inhibitor AUY922 plus Capecitabine for the Treatment of Patients with Advanced Solid Tumors.
Neoplasms
A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients.
Neoplasms
A phase I trial of vorinostat and bortezomib in children with refractory or recurrent solid tumors: A Children's Oncology Group phase I consortium study (ADVL0916).
Neoplasms
A phase I-II study of the histone deacetylase inhibitor vorinostat plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in locally advanced breast cancer.
Neoplasms
A Phase II Study of Ganetespib as Second-line or Third-line Therapy for Metastatic Pancreatic Cancer.
Neoplasms
A phase II study of gemcitabine in combination with tanespimycin in advanced epithelial ovarian and primary peritoneal carcinoma.
Neoplasms
A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia.
Neoplasms
A phase II trial of ganetespib, a heat shock protein 90 Hsp90) inhibitor, in patients with docetaxel-pretreated metastatic castrate-resistant prostate cancer (CRPC)-a prostate cancer clinical trials consortium (PCCTC) study.
Neoplasms
A Physiologically-Based Pharmacokinetic Model of Alvespimycin in Mice and Extrapolation to Rats and Humans.
Neoplasms
A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study.
Neoplasms
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells.
Neoplasms
A Preliminary Study on RCN3 Protein Expression in Non-small Cell Lung Cancer.
Neoplasms
A prescription for 'stress' - the role of Hsp90 in genome stability and cellular adaptation.
Neoplasms
A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization.
Neoplasms
A proteomic approach towards the Hsp90-dependent ubiquitinylated proteome.
Neoplasms
A proteomic study of the differential protein expression in MDBK cells after bovine herpesvirus type 1 infection (BHV-1) strain treatment.
Neoplasms
A pyrrole-based natural small molecule mitigates HSP90 expression in MDA-MB-231 cells and inhibits tumor angiogenesis in mice by inactivating HSF-1.
Neoplasms
A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients.
Neoplasms
A repurposing strategy for Hsp90 inhibitors demonstrates their potency against filarial nematodes.
Neoplasms
A review of recent patents on the protozoan parasite HSP90 as a drug target.
Neoplasms
A role for HMGB1, HSP60 and Myd88 in growth of murine mammary carcinoma in vitro.
Neoplasms
A role of Rab7 in stabilizing EGFR-Her2 and in sustaining Akt survival signal.
Neoplasms
A Scaffold Merging Approach to Hsp90 C-terminal Inhibition: Synthesis and Evaluation of a Chimeric Library.
Neoplasms
A secreted Heat shock protein 90 of Trichomonas vaginalis.
Neoplasms
A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa heat shock protein HSP90AA1 and its client proteins in cancer cells.
Neoplasms
A signal peptide derived from Hsp60 induces protective cytotoxic T lymphocyte immunity against lymphoid malignancies independently of TAP and classical MHC-I.
Neoplasms
A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90alpha/beta.
Neoplasms
A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion.
Neoplasms
A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells.
Neoplasms
A small molecule inhibitor of inducible heat shock protein 70.
Neoplasms
A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Neoplasms
A Targetable Molecular Chaperone Hsp27 Confers Aggressiveness in Hepatocellular Carcinoma.
Neoplasms
A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation.
Neoplasms
A time-resolved fluorescence resonance energy transfer-based HTS assay and a surface plasmon resonance-based binding assay for heat shock protein 90 inhibitors.
Neoplasms
A trial of SGN-00101 (HspE7) to treat high-grade anal intraepithelial neoplasia in HIV-positive individuals.
Neoplasms
A triazine compound S06 inhibits proinvasive crosstalk between carcinoma cells and stromal fibroblasts via binding to heat shock protein 90.
Neoplasms
A tumor-targeted Ganetespib-zinc phthalocyanine conjugate for synergistic chemo-photodynamic therapy.
Neoplasms
A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration.
Neoplasms
AAA+ ATPases Reptin and Pontin as potential diagnostic and prognostic biomarkers in salivary gland cancer - a short report.
Neoplasms
Aberrant expression of stress-induced phosphoprotein 1 in colorectal cancer and its clinicopathologic significance.
Neoplasms
Ablation of elongation factor 2 kinase enhances heat-shock protein 90 chaperone expression and protects cells under proteotoxic stress.
Neoplasms
Abnormal cell cycle regulation in primary human uveal melanoma cultures.
Neoplasms
Absence of caveolin-1 alters heat shock protein expression in spontaneous mammary tumors driven by Her-2/neu expression.
Neoplasms
Abundance of heat shock proteins (hsp89, hsp60, and hsp27) in malignant cells of Hodgkin's disease.
Neoplasms
Accelerated, but not conventional, radiotherapy of murine B-cell lymphoma induces potent T cell-mediated remissions.
Neoplasms
Acetylation modification regulates GRP78 secretion in colon cancer cells.
Neoplasms
Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer.
Neoplasms
Acidic stress facilitates tyrosine phosphorylation of HLJ1 to associate with actin cytoskeleton in lung cancer cells.
Neoplasms
Acidosis acts through HSP90 in a PHD/VHL-independent manner to promote HIF function and stem cell maintenance in glioma.
Neoplasms
Acquired resistance to 5-fluorouracil via HSP90/Src-mediated increase in thymidylate synthase expression in colon cancer.
Neoplasms
Acquired resistance to HSP90 inhibitor 17-AAG and increased metastatic potential are associated with MUC1 expression in colon carcinoma cells.
Neoplasms
Activated ?2-macroglobulin binding to cell surface GRP78 induces trophoblastic cell fusion.
Neoplasms
Activated ?2-Macroglobulin Regulates Transcriptional Activation of c-Myc Target Genes Through Cell Surface GRP78.
Neoplasms
Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition.
Neoplasms
Activation and clinical significance of the unfolded protein response in breast cancer.
Neoplasms
Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.
Neoplasms
Activation of mitochondrial unfolded protein response is associated with Her2-overexpression breast cancer.
Neoplasms
Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma.
Neoplasms
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis.
Neoplasms
Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides.
Neoplasms
Active-specific immunotherapy of human cancers with the heat shock protein Gp96-revisited.
Neoplasms
Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.
Neoplasms
Activity of the heat shock protein 90 inhibitor ganetespib in melanoma.
Neoplasms
Acute cadmium exposure enhances AP-1 DNA binding and induces cytokines expression and heat shock protein 70 in HepG2 cells.
Neoplasms
Adapted ATPase domain communication overcomes the cytotoxicity of p97 inhibitors.
Neoplasms
Additive viability-loss following hsp70/hsc70 double interference and Hsp90 inhibition in two breast cancer cell lines.
Neoplasms
Adeno-associated virus mediated gene transfer of Shepherdin inhibits gallbladder carcinoma growth in vitro and in vivo.
Neoplasms
Adenomatous polyposis coli mutants dominantly activate Hsf1-dependent cell stress pathways through inhibition of microtubule dynamics.
Neoplasms
Adenosine-derived inhibitors of 78 kDa glucose regulated protein (Grp78) ATPase: insights into isoform selectivity.
Neoplasms
Adenovirus E1A, not human papillomavirus E7, sensitizes tumor cells to lysis by macrophages through nitric oxide- and TNF-alpha-dependent mechanisms despite up-regulation of 70-kDa heat shock protein.
Neoplasms
ADP-ribosylation inhibitors inhibit cellular RNA synthesis but do not affect expression of manganous superoxide dismutase or heat shock protein 70 in tumor necrosis factor alpha-sensitive and -resistant tumor cells.
Neoplasms
Advances in HSP27 and HSP90-targeting strategies for glioblastoma.
Neoplasms
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers.
Neoplasms
Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment.
Neoplasms
Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.
Neoplasms
Aggregatibacter actinomycetemcomitans accelerates atherosclerosis with an increase in atherogenic factors in spontaneously hyperlipidemic mice.
Neoplasms
AIDing cancer treatment: Reducing AID activity via HSP90 inhibition.
Neoplasms
Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer.
Neoplasms
Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways.
Neoplasms
AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers.
Neoplasms
Akt shows variable sensitivity to an Hsp90 inhibitor depending on cell context.
Neoplasms
Alanyl?glutamine prophylactically protects against lipopolysaccharide?induced acute lung injury by enhancing the expression of HSP70.
Neoplasms
ALK inhibitors in non-small cell lung cancer: crizotinib and beyond.
Neoplasms
Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).
Neoplasms
Alleviative effect of selenium on inflammatory damage caused by lead via inhibiting inflammatory factors and heat shock proteins in chicken testes.
Neoplasms
Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group.
Neoplasms
Alpha B crystallin expression in response to hormone, oncogenes and stress.
Neoplasms
AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer.
Neoplasms
AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas.
Neoplasms
Alterations in trace element levels and mRNA expression of Hsps and inflammatory cytokines in livers of duck exposed to molybdenum or/and cadmium.
Neoplasms
Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer.
Neoplasms
Altered Hsp90 function in cancer: a unique therapeutic opportunity.
Neoplasms
Altered molecular pathways decides the treatment outcome of Hsp90 inhibitors against breast cancer cells.
Neoplasms
Altered states: selectively drugging the Hsp90 cancer chaperone.
Neoplasms
Alternate Strategies of Hsp90 Modulation for the Treatment of Cancer and Other Diseases.
Neoplasms
Alternative approaches to Hsp90 modulation for the treatment of cancer.
Neoplasms
Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72.
Neoplasms
Amelioration of renal ischaemia-reperfusion injury by liposomal delivery of curcumin to renal tubular epithelial and antigen presenting cells.
Neoplasms
Ameliorative effect of vitamin E on hepatic oxidative stress and hypoimmunity induced by high-fat diet in turbot (Scophthalmus maximus).
Neoplasms
An immunodominant MHC class II-restricted tumor antigen is conformation dependent and binds to the endoplasmic reticulum chaperone, calreticulin.
Neoplasms
An Impermeant Ganetespib Analog Inhibits Extracellular Hsp90-Mediated Cancer Cell Migration that Involves Lysyl Oxidase 2-like Protein.
Neoplasms
An improved route to 19-substituted geldanamycins as novel Hsp90 inhibitors - potential therapeutics in cancer and neurodegeneration.
Neoplasms
An investigation into the potential use of serum Hsp70 as a novel tumour biomarker for Hsp90 inhibitors.
Neoplasms
An updated patent review of anticancer Hsp90 inhibitors (2013-present).
Neoplasms
Analogs of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, as Anti-Cancer Agents.
Neoplasms
Analysis of 8-hydroxyguanine in rat kidney genomic DNA after administration of a renal carcinogen, ferric nitrilotriacetate.
Neoplasms
Analysis of conformational determinants underlying HSP90-kinase interaction.
Neoplasms
Analysis of differently expressed proteins involved in metastatic niche of lung.
Neoplasms
Analysis of expression of heat shock protein-90 (HSP90) and the effects of HSP90 inhibitor (17-AAG) in multiple myeloma.
Neoplasms
Analysis of gene and protein expression of cytochrome P450 and stress-associated molecules in rat liver after spaceflight.
Neoplasms
Analysis of heat shock proteins and cytokines expressed during early stages of osteoarthritis in a mouse model.
Neoplasms
Analysis of Hsp90 allosteric modulators interactome reveals a potential dual action mode involving mitochondrial MDH2.
Neoplasms
Analysis of HSP90 Expression Is Valuable in the Differential Diagnosis of Ocular Surface Squamous Lesions.
Neoplasms
Analysis of MHC genes in a Tunisian isolate with autoimmune thyroid diseases: implication of TNF -308 gene polymorphism.
Neoplasms
Analysis of polypeptide expression in benign and malignant human breast lesions.
Neoplasms
ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2.
Neoplasms
Androgen receptor (AR) expression is an independent unfavorable prognostic factor in gastric cancer.
Neoplasms
Androgen receptor and heat shock protein 27 co-regulate the malignant potential of molecular apocrine breast cancer.
Neoplasms
Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers.
Neoplasms
Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer.
Neoplasms
Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy.
Neoplasms
Andrographolide-induced apoptosis in human renal tubular epithelial cells: Roles of endoplasmic reticulum stress and inflammatory response.
Neoplasms
Anesthesia for euthanasia influences mRNA expression in healthy mice and after traumatic brain injury.
Neoplasms
Aneuploidy and proteotoxic stress in cancer.
Neoplasms
Ansamycin Inhibitors of Hsp90: Nature's Prototype for Anti-Chaperone Therapy.
Neoplasms
Anti-breast tumor activity of Eclipta extract in-vitro and in-vivo: novel evidence of endoplasmic reticulum specific localization of Hsp60 during apoptosis.
Neoplasms
Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins.
Neoplasms
Anti-citrullinated peptide antibodies bind surface-expressed citrullinated GRP78 on monocytes/macrophages stimulate tumor necrosis factor-alpha production.
Neoplasms
Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions.
Neoplasms
Anti-HSP auto-antibodies enhance HSP-induced pro-inflammatory cytokine production in human monocytic cells via Toll-like receptors.
Neoplasms
Anti-inflammatory Potential of Petiveria alliacea on Activated RAW264.7 Murine Macrophages.
Neoplasms
Anti-intoxication and protective effects of a recombinant serine protease inhibitor from Lentinula edodes against acute alcohol-induced liver injury in mice.
Neoplasms
Anti-KDEL-coated nanoparticles: A promising tumor targeting approach for ovarian cancer?
Neoplasms
Anti-malaria drug blocks proteotoxic stress response: anti-cancer implications.
Neoplasms
Anti-myeloma activity of the novel 2-aminothienopyrimidine Hsp90 inhibitor NVP-BEP800.
Neoplasms
Anti-NSCLC activity in vitro of Hsp90N inhibitor KW-2478 and complex crystal structure determination of Hsp90N-KW-2478.
Neoplasms
Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines.
Neoplasms
Anti-tumor immune responses following neoadjuvant immunotherapy with a recombinant adenovirus expressing HSP72 to rodent tumors.
Neoplasms
Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer.
Neoplasms
Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non-Small Cell Lung Cancer Cell Lines and Tumor Models.
Neoplasms
Anticancer Activity in Honeybee Propolis: Functional Insights to the Role of Caffeic Acid Phenethyl Ester and Its Complex With ?-Cyclodextrin.
Neoplasms
Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.
Neoplasms
Anticancer activity of methylene blue via inhibition of heat shock protein 70.
Neoplasms
Anticancer drugs up-regulate HspBP1 and thereby antagonize the prosurvival function of Hsp70 in tumor cells.
Neoplasms
Anticancer effects of ginsenoside Rg1, cinnamic acid, and tanshinone IIA in osteosarcoma MG-63 cells: nuclear matrix downregulation and cytoplasmic trafficking of nucleophosmin.
Neoplasms
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
Neoplasms
Antileukemic activity of the HSP70 inhibitor pifithrin-? in acute leukemia.
Neoplasms
Antimelanoma activity of apoptogenic carbonyl scavengers.
Neoplasms
Antimyeloma activity of heat shock protein-90 inhibition.
Neoplasms
Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells.
Neoplasms
Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer.
Neoplasms
Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer.
Neoplasms
Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress.
Neoplasms
Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer.
Neoplasms
Antitumor activity of efrapeptins, alone or in combination with 2-deoxyglucose, in breast cancer in vitro and in vivo.
Neoplasms
Antitumor activity of mHSP65-TTL enhanced by administration of low dose cyclophosphamide in pancreatic cancer-bearing mice.
Neoplasms
Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins.
Neoplasms
Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition.
Neoplasms
Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma.
Neoplasms
Antitumor effect of novel HSP90 inhibitor NVP-AUY922 against oral squamous cell carcinoma.
Neoplasms
Antitumor effect of reduction of 150-kDa oxygen-regulated protein expression on human prostate cancer cells.
Neoplasms
Antitumor Effects and the Compatibility Mechanisms of Herb Pair Scleromitrion diffusum (Willd.) R. J. Wang-Sculellaria barbata D. Don.
Neoplasms
Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2-positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib.
Neoplasms
Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor.
Neoplasms
Application of differential display, with in situ hybridization verification, to microscopic samples of breast cancer tissue.
Neoplasms
Application of docking-based comparative intermolecular contacts analysis to validate Hsp90? docking studies and subsequent in silico screening for inhibitors.
Neoplasms
Approaches for defining the Hsp90-dependent proteome.
Neoplasms
Aptamer-Peptide Conjugates as Targeted Chemosensitizers for Breast Cancer Treatment.
Neoplasms
Aqueous Terminalia arjuna extract modulates expression of key atherosclerosis-related proteins in a hypercholesterolemic rabbit: A proteomic-based study.
Neoplasms
Are IgG antibodies to heat shock proteins HSP27 and HSP60 useful markers in endometrial cancer and cervical cancer?
Neoplasms
Areca nut contributes to oral malignancy through facilitating the conversion of cancer stem cells.
Neoplasms
Arginine-Arginine-Leucine Peptide Targeting Heat Shock Protein 70 for Cancer Imaging.
Neoplasms
Arsenic trioxide exerts antimyeloma effects by inhibiting activity in the cytoplasmic substrates of histone deacetylase 6.
Neoplasms
Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligase.
Neoplasms
Arsenic-induced testicular toxicity in Gallus gallus: Expressions of inflammatory cytokines and heat shock proteins.
Neoplasms
Assay design and development strategies for finding Hsp90 inhibitors and their role in human diseases.
Neoplasms
Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90.
Neoplasms
Assays for Identification of Hsp90 Inhibitors and Biochemical Methods for Discriminating their Mechanism of Action.
Neoplasms
Assessing the chemical diversity of an hsp90 database.
Neoplasms
Assessing the Impact of HER2 Status on the Antitumor Activity of an HSP90 Inhibitor in Human Tumor Xenograft Mice using Pharmacokinetics-Pharmacodynamic Modeling.
Neoplasms
Assisting anti-PD-1 antibody treatment with a liposomal system capable of recruiting immune cells.
Neoplasms
Association between Alpha B-crystallin expression and prognosis in patients with solid tumors: A protocol for systematic review and meta-analysis.
Neoplasms
Association between heat shock protein 70 gene polymorphisms and clinical outcomes in intensive care unit patients with sepsis.
Neoplasms
Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: a mechanistic study employing molecular genomics.
Neoplasms
Association between vaginal 70-kd heat shock protein, interleukin-1 receptor antagonist, and microbial flora in mid trimester pregnant women.
Neoplasms
Association of Alpha B-Crystallin Expression with Tumor Differentiation Grade in Colorectal Cancer Patients.
Neoplasms
Association of elevated GRP78 expression with increased astrocytoma malignancy via Akt and ERK pathways.
Neoplasms
Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer.
Neoplasms
Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells.
Neoplasms
Association of mortalin (HSPA9) with liver cancer metastasis and prediction for early tumor recurrence.
Neoplasms
Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells.
Neoplasms
Association of tapasin and HLA class I antigen down-regulation in primary maxillary sinus squamous cell carcinoma lesions with reduced survival of patients.
Neoplasms
Associations between the Nrf2/Keap1 pathway and mitochondrial functions in colorectal cancer are affected by metastasis.
Neoplasms
Associations of HSP90 client proteins in human breast cancer.
Neoplasms
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors.
Neoplasms
AT-533, a novel Hsp90 inhibitor, inhibits breast cancer growth and HIF-1?/VEGF/VEGFR-2-mediated angiogenesis in vitro and in vivo.
Neoplasms
ATAD3A stabilizes GRP78 to suppress ER stress for acquired chemoresistance in colorectal cancer.
Neoplasms
ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system.
Neoplasms
Attenuated phosphorylation of heat shock protein 27 correlates with tumor progression in patients with hepatocellular carcinoma.
Neoplasms
Attenuating effects of coenzyme Q10 and amlodipine in ulcerative colitis model in rats.
Neoplasms
Augmentation of antitumor immunity by fusions of ethanol-treated tumor cells and dendritic cells stimulated via dual TLRs through TGF-?1 blockade and IL-12p70 production.
Neoplasms
Augmentation of immune cell activity against tumor cells by Rauwolfia radix.
Neoplasms
Author Correction: Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations.
Neoplasms
Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma.
Neoplasms
Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.
Neoplasms
Autoantibody to heat shock protein Hsp40 in sera of lung cancer patients.
Neoplasms
Autoimmunity in chronic active Helicobacter hepatitis of mice. Serum antibodies and expression of heat shock protein 70 in liver.
Neoplasms
Autologous Hsp70 induces antigen specific Th1 immune responses in a murine T-cell lymphoma.
Neoplasms
Autophagy gene fingerprint in human ischemia and reperfusion.
Neoplasms
Autophagy in the physiological endometrium and cancer.
Neoplasms
Autoreactive T cells from normal mice recognize mycobacterial 65 kd heat-shock protein from Mycobacterium bovis.
Neoplasms
AUY922 induces retinal toxicity through attenuating TRPM1.
Neoplasms
Bacterial heat shock proteins directly induce cytokine mRNA and interleukin-1 secretion in macrophage cultures.
Neoplasms
Bacterial production and functional characterization of the Fab fragment of the murine IgG1/lambda monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics.
Neoplasms
BAG-1/SODD, HSP70 and HSP90 are potential prognostic markers of poor survival in node-negative breast carcinoma.
Neoplasms
BAG-1: a multifunctional regulator of cell growth and survival.
Neoplasms
Bag-3 expression is involved in pathogenesis and progression of colorectal carcinomas.
Neoplasms
BAG-i expression in human breast cancer: interrelationship between BAG-1 RNA, protein, HSC70 expression and clinico-pathological data.
Neoplasms
BAG3 controls angiogenesis through regulation of ERK phosphorylation.
Neoplasms
BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion.
Neoplasms
BAG3 Protein Is Involved in Endothelial Cell Response to Phenethyl Isothiocyanate.
Neoplasms
BAG3 sensitizes cancer cells exposed to DNA damaging agents via direct interaction with GRP78.
Neoplasms
Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.
Neoplasms
BDNF, TNF?, HSP90, CFH, and IL-10 Serum Levels in Patients with Early or Late Onset Alzheimer's Disease or Mild Cognitive Impairment.
Neoplasms
Beneficial effects of dietary ?-glucan on growth and health status of Pacific white shrimp Litopenaeus vannamei at low salinity.
Neoplasms
Benfotiamine Attenuates Inflammatory Response in LPS Stimulated BV-2 Microglia.
Neoplasms
Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis.
Neoplasms
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.
Neoplasms
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Neoplasms
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting.
Neoplasms
Bi2 S3 -Tween 20 Nanodots Loading PI3K Inhibitor, LY294002, for Mild Photothermal Therapy of LoVo Cells In Vitro and In Vivo.
Neoplasms
BIIB021, a novel Hsp90 inhibitor, sensitizes esophageal squamous cell carcinoma to radiation.
Neoplasms
BIIB021, a novel HSP90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy.
Neoplasms
BIIB021, a synthetic HSP90 inhibitor, has broad application against tumors with acquired multidrug resistance.
Neoplasms
BIIB021, an Hsp90 inhibitor, effectively kills a myelodysplastic syndrome cell line via the activation of caspases and inhibition of PI3K/Akt and NF-?B pathway proteins.
Neoplasms
BIIB021, an Hsp90 inhibitor: A promising therapeutic strategy for blood malignancies (Review).
Neoplasms
BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90.
Neoplasms
BIIB021: A novel inhibitor to heat shock protein 90-addicted oncology.
Neoplasms
BIK and GRP78 protein expression as possible markers of response to preoperative chemotherapy and survival in breast cancer.
Neoplasms
Bim transfer between Bcl-2-like protein and Hsp70 underlines Bcl-2/Hsp70 crosstalk to regulate apoptosis.
Neoplasms
Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.
Neoplasms
Binding of antigenic peptide to the endoplasmic reticulum-resident protein gp96/GRP94 heat shock chaperone occurs in higher order complexes. Essential role of some aromatic amino acid residues in the peptide-binding site.
Neoplasms
Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells.
Neoplasms
Binding of natural and synthetic inhibitors to human heat shock protein 90 and their clinical application.
Neoplasms
Binding of tumor antigen mucin (MUC1) derived peptides to the heat shock protein DnaK.
Neoplasms
Binding partners for curcumin in human schwannoma cells: biologic implications.
Neoplasms
BIO alleviates inflammation through inhibition of GSK-3? in a rat model of intracerebral hemorrhage.
Neoplasms
Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1).
Neoplasms
Biodistribution of HPMA Copolymer-Aminohexylgeldanamycin-RGDfK Conjugates for Prostate Cancer Drug Delivery.
Neoplasms
Biologic markers of invasive pituitary adenomas involving the sphenoid sinus.
Neoplasms
Biological characteristics of heat shock protein 90 in human liver cancer cells.
Neoplasms
Biological evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones as inhibitors of Hsp90 chaperoning function.
Neoplasms
Biological Evaluation of 5'-(N-Ethylcarboxamido)adenosine Analogues as Grp94-Selective Inhibitors.
Neoplasms
Biomarkers That Predict Sensitivity to Heat Shock Protein 90 Inhibitors.
Neoplasms
Biophysical analysis of the endoplasmic reticulum-resident chaperone/heat shock protein gp96/GRP94 and its complex with peptide antigen.
Neoplasms
Bioresistive identification of heat shock protein 90.
Neoplasms
Biotinylated geldanamycin.
Neoplasms
BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth.
Neoplasms
Blinded predictions of binding modes and energies of HSP90-? ligands for the 2015 D3R grand challenge.
Neoplasms
Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways.
Neoplasms
Blockade of Her2/neu Binding to Hsp90 by Emodin Azide Methyl Anthraquinone Derivative Induces Proteasomal Degradation of Her2/neu.
Neoplasms
Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors.
Neoplasms
Blockade of PI3K/AKT pathway enhances sensitivity of Raji cells to chemotherapy through down-regulation of HSP70.
Neoplasms
Blockage of conformational changes of heat shock protein gp96 on cell membrane by a ?-helix peptide inhibits HER2 dimerization and signaling in breast cancer.
Neoplasms
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Neoplasms
Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression.
Neoplasms
Blocking NF-?B and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death.
Neoplasms
Blocking NF-?B sensitizes non-small cell lung cancer cells to histone deacetylase inhibitor induced extrinsic apoptosis through generation of reactive oxygen species.
Neoplasms
Blocking the chaperone kinome pathway: mechanistic insights into a novel dual inhibition approach for supra-additive suppression of malignant tumors.
Neoplasms
Boosting Photothermal Theranostics via TICT and Molecular Motions for Photohyperthermia Therapy of Muscle-Invasive Bladder Cancer.
Neoplasms
Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications.
Neoplasms
Both CD4+ and CD8+ T cell epitopes fused to heat shock cognate protein 70 (hsc70) can function to eradicate tumors.
Neoplasms
BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation.
Neoplasms
Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell characteristics.
Neoplasms
c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells.
Neoplasms
C-C Chemokine Ligand 2 (CCL2) Recruits Macrophage-Membrane-Camouflaged Hollow Bismuth Selenide Nanoparticles To Facilitate Photothermal Sensitivity and Inhibit Lung Metastasis of Breast Cancer.
Neoplasms
C-Mannosylated peptides derived from the thrombospondin type 1 repeat interact with Hsc70 to modulate its signaling in RAW264.7 cells.
Neoplasms
C-terminal amino acids are essential for human heat shock protein 70 dimerization.
Neoplasms
C-terminal domain of SMYD3 serves as a unique HSP90-regulated motif in oncogenesis.
Neoplasms
C-terminal HSP90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Neoplasms
C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1? through the Oxygen-Dependent Degradation Pathway.
Neoplasms
C-terminal modulators of heat shock protein of 90?kDa (HSP90): State of development and modes of action.
Neoplasms
C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances.
Neoplasms
C0818, a novel curcumin derivative, induces ROS-dependent cytotoxicity in human hepatocellular carcinoma cells in vitro via disruption of Hsp90 function.
Neoplasms
C15-methoxyphenylated 18-deoxy-herbimycin A analogues, their in vitro anticancer activity and heat shock protein 90 binding affinity.
Neoplasms
Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib.
Neoplasms
Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
Neoplasms
Calreticulin is involved in invasion of human extravillous trophoblasts through functional regulation of integrin ?1.
Neoplasms
Can breast cancer Hsp 27 (Heat Shock Protein 27000) expression influence axillary lymph node status?
Neoplasms
Can RNAi-mediated hsp90? knockdown in combination with 17-AAG be a therapy for glioma?
Neoplasms
Cancer abolishes the tissue type-specific differences in the phenotype of energetic metabolism.
Neoplasms
Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform.
Neoplasms
Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations.
Neoplasms
Cancer cells harboring MET gene amplification activate alternative signaling pathways to escape MET inhibition but remain sensitive to Hsp90 inhibitors.
Neoplasms
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production.
Neoplasms
Cancer Chemoprevention and Nutri-Epigenetics: State of the Art and Future Challenges.
Neoplasms
Cancer gene therapy with a heat shock protein gene.
Neoplasms
Cancer immunotherapy based on intracellular hyperthermia using magnetite nanoparticles: a novel concept of "heat-controlled necrosis" with heat shock protein expression.
Neoplasms
Cancer immunotherapy using irradiated tumor cells secreting heat shock protein 70.
Neoplasms
Cancer inhibition through circadian reprogramming of tumor transcriptome with meal timing.
Neoplasms
Cancer progression in COVID-19: integrating the roles of renin angiotensin aldosterone system, angiopoietin-2, heat shock protein-27 and epithelial mesenchymal transition.
Neoplasms
Cancer proteomics: from identification of novel markers to creation of artifical learning models for tumor classification.
Neoplasms
Cancer Takes a Toll on Skeletal Muscle by Releasing Heat Shock Proteins-An Emerging Mechanism of Cancer-Induced Cachexia.
Neoplasms
Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device.
Neoplasms
Cancer-selective apoptotic effects of extracellular and intracellular Par-4.
Neoplasms
Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype-associated gene expression signatures.
Neoplasms
Canine heat shock protein 27 promotes proliferation, migration, and doxorubicin resistance in the canine cell line DTK-F.
Neoplasms
Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors.
Neoplasms
Carboxy-terminus Hsc70 interacting protein exerts a tumor inhibition function in head and neck cancer.
Neoplasms
Carcinosarcoma of the urinary bladder: expression of epithelial markers and different expression of heat shock proteins between epithelial and sarcomatous elements.
Neoplasms
Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity.
Neoplasms
Castration-Induced Downregulation of SPARC in Stromal Cells Drives Neuroendocrine Differentiation of Prostate Cancer.
Neoplasms
CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells.
Neoplasms
CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.
Neoplasms
CD20+ Tumor Infiltrating B Lymphocyte in Oral Squamous Cell Carcinoma: Correlation with Clinicopathologic Characteristics and Heat Shock Protein 70 Expression.
Neoplasms
Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.
Neoplasms
Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.
Neoplasms
Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way.
Neoplasms
Celecoxib induces apoptosis but up-regulates VEGF via endoplasmic reticulum stress in human colorectal cancer in vitro and in vivo.
Neoplasms
Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells.
Neoplasms
Cell death induced by down-regulation of heat shock protein 70 in lung cancer cell lines is p53-independent and does not require DNA cleavage.
Neoplasms
Cell Surface Cdc37 Participates in Extracellular HSP90 Mediated Cancer Cell Invasion.
Neoplasms
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands.
Neoplasms
Cell surface GRP78 and Dermcidin cooperate to regulate breast cancer cell migration through Wnt signaling.
Neoplasms
Cell surface GRP78 as a biomarker and target for suppressing glioma cells.
Neoplasms
Cell Surface GRP78 as a Death Receptor and an Anticancer Drug Target.
Neoplasms
Cell surface GRP78 promotes stemness in normal and neoplastic cells.
Neoplasms
Cell surface GRP78 promotes tumor cell histone acetylation through metabolic reprogramming: a mechanism which modulates the Warburg effect.
Neoplasms
Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancer.
Neoplasms
Cell surface GRP78: A potential marker of good prognosis and response to chemotherapy in breast cancer.
Neoplasms
Cell surface GRP78: An emerging imaging marker and therapeutic target for cancer.
Neoplasms
Cell surface heat shock protein 90 modulates prostate cancer cell adhesion and invasion through the integrin-?1/focal adhesion kinase/c-Src signaling pathway.
Neoplasms
Cell surface heat shock protein-mediated entry of tumor cell-adapted rotavirus into U-937 cells.
Neoplasms
Cell surface heparan sulfate proteoglycans are involved in the extracellular Hsp90-stimulated migration and invasion of cancer cells.
Neoplasms
Cell surface localised Hsp70 is a cancer specific regulator of clathrin-independent endocytosis.
Neoplasms
Cell surface receptors for molecular chaperones.
Neoplasms
Cell surface targeting of heat shock protein gp96 induces dendritic cell maturation and antitumor immunity.
Neoplasms
Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.
Neoplasms
Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.
Neoplasms
Cellular and molecular chaperone fusion vaccines: targeting resistant cancer cell populations.
Neoplasms
Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.
Neoplasms
Cepharanthin enhances thermosensitivity without a resultant reduction in the thermotolerance of a murine mammary carcinoma.
Neoplasms
CEUS-Based Radiomics Can Show Changes in Protein Levels in Liver Metastases After Incomplete Thermal Ablation.
Neoplasms
Chaetocin enhances dendritic cell function via the induction of heat shock protein and cancer testis antigens in myeloma cells.
Neoplasms
Chalcone-templated Hsp90 inhibitors and their effects on gefitinib resistance in non-small cell lung cancer (NSCLC).
Neoplasms
Changes in cell culture temperature alter release of inflammatory mediators in murine macrophagic RAW264.7 cells.
Neoplasms
Changes in inflammatory mediators following eccentric exercise of the elbow flexors.
Neoplasms
Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survival.
Neoplasms
Changes in protein expression after neoadjuvant use of aromatase inhibitors in primary breast cancer: a proteomic approach to search for potential biomarkers to predict response or resistance.
Neoplasms
Changes in the expression of proteins associated with aerobic glycolysis and cell migration are involved in tumorigenic ability of two glioma cell lines.
Neoplasms
Changes in tumor necrosis factor-?, heat shock protein 70, malondialdehyde, and superoxide dismutase in patients with different severities of alcoholic fatty liver disease: a prospective observational study.
Neoplasms
Chaperone gp96-independent inhibition of endotoxin response by chaperone-based peptide inhibitors.
Neoplasms
Chaperone Mediated Autophagy Substrates and Components in Cancer.
Neoplasms
Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.
Neoplasms
Chaperone substrate provides missing link for cancer drug discovery.
Neoplasms
Chaperone-dependent stabilization and degradation of p53 mutants.
Neoplasms
Chaperone-mediated autophagy promotes lung cancer cell survival through selective stabilization of the pro-survival protein, MCL1.
Neoplasms
Chaperone-rich cell lysates, immune activation and tumor vaccination.
Neoplasms
Chaperones and slow death--a recipe for tumor immunotherapy.
Neoplasms
Chaperonin-Co-chaperonin Interactions.
Neoplasms
Chaperonin-GroEL as a Smart Hydrophobic Drug Delivery and Tumor Targeting Molecular Machine for Tumor Therapy.
Neoplasms
Chaperoning of mutant p53 protein by wild-type p53 protein causes hypoxic tumor regression.
Neoplasms
Chaperoning oncogenes: Hsp90 as a target of geldanamycin.
Neoplasms
Chaperonopathies and Chaperonotherapy. Hsp60 as Therapeutic Target in Cancer: Potential Benefits and Risks.
Neoplasms
Characterization and Biological Activity of the Ribosomal Protein L10a of the White Shrimp: Fenneropenaeus merguiensis De Man During Vitellogenesis.
Neoplasms
Characterization and Mechanism of Stress-induced Translocation of 78-kilodalton Glucose Regulated Protein (GRP78) to the Cell Surface.
Neoplasms
Characterization and prognostic significance of mortalin, Bcl-2 and Bax in intrahepatic cholangiocarcinoma.
Neoplasms
Characterization of celastrol to inhibit HSP90 and CDC37 interaction.
Neoplasms
Characterization of Exosomes in Plasma of Patients with Breast, Ovarian, Prostate, Hepatic, Gastric, Colon, and Pancreatic Cancers.
Neoplasms
Characterization of Glycolysis-Associated Molecules in the Tumor Microenvironment Revealed by Pan-Cancer Tissues and Lung Cancer Single Cell Data.
Neoplasms
Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity.
Neoplasms
Characterization of six new loci within the swine major histocompatibility complex class III region.
Neoplasms
Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.
Neoplasms
Characterization of the combined cellular survival effects of benzoquinone-ansamycins and ionizing radiation.
Neoplasms
Characterization of the Relationship between the Chaperone and Lipid-Binding Functions of the 70-kDa Heat-Shock Protein, HspA1A.
Neoplasms
Characterizing Cell Stress and GRP78 in Glioma to Enhance Tumor Treatment.
Neoplasms
Chemical inhibition of HSP90 inhibits TNF-? mediated proliferation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes.
Neoplasms
Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions.
Neoplasms
Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.
Neoplasms
Chemodrug-Gated Biodegradable Hollow Mesoporous Organosilica Nanotheranostics for Multimodal Imaging-Guided Low-Temperature Photothermal Therapy/Chemotherapy of Cancer.
Neoplasms
Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1.
Neoplasms
Chemotherapy Sensitizes Therapy-Resistant Cells to Mild Hyperthermia by Suppressing Heat Shock Protein 27 Expression in Triple-Negative Breast Cancer.
Neoplasms
Chicken HSP70 DNA vaccine inhibits tumor growth in a canine cancer model.
Neoplasms
CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer.
Neoplasms
CHIP is a novel tumor suppressor in pancreatic cancer through targeting EGFR.
Neoplasms
Chiral resolution and pharmacological characterization of the enantiomers of the Hsp90 inhibitor 2-amino-7-[4-fluoro-2-(3-pyridyl)phenyl]-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime.
Neoplasms
Chitosan-functionalised single-walled carbon nanotube-mediated drug delivery of SNX-2112 in cancer cells.
Neoplasms
CHM-1 Suppresses Formation of Cell Surface-associated GRP78-p85? Complexes, Inhibiting PI3K-AKT Signaling and Inducing Apoptosis of Human Nasopharyngeal Carcinoma Cells.
Neoplasms
Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cells.
Neoplasms
Circulating GRP78 antibodies from ovarian cancer patients: a promising tool for cancer cell targeting drug delivery system?
Neoplasms
Circulating heat shock proteins in women with a history of recurrent vulvovaginitis.
Neoplasms
Circulating human heat shock protein 60 in the plasma of British civil servants: relationship to physiological and psychosocial stress.
Neoplasms
Circulating level of heat shock protein 27 is elevated in dogs with mammary tumors.
Neoplasms
Circulating mitochondrial stress 70 protein/mortalin and cytosolic Hsp70 in blood: Risk indicators in colorectal cancer.
Neoplasms
Circulating mortalin autoantibody--a new serological marker of liver cirrhosis.
Neoplasms
Cisplatin induces the small heat shock protein hsp25 and thermotolerance in Ehrlich ascites tumor cells.
Neoplasms
Cisplatin-induced senescence in ovarian cancer cells is mediated by GRP78.
Neoplasms
CK2: The kinase controlling the Hsp90 chaperone machinery.
Neoplasms
Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.
Neoplasms
Cleavage of HSP90? induced by histone deacetylase inhibitor and proteasome inhibitor modulates cell growth and apoptosis.
Neoplasms
Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.
Neoplasms
Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.
Neoplasms
Clinical development of 17-allylamino, 17-demethoxygeldanamycin.
Neoplasms
Clinical significance of HSP27 expression in colorectal cancer.
Neoplasms
Clinical Significance of Monitoring Circulating Free DNA and Plasma Heat Shock Protein 90alpha in Patients with Esophageal Squamous Cell Carcinoma.
Neoplasms
Clinical significance of serum dynamics of HSP90a level in esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy.
Neoplasms
Clinical, Prognostic and Therapeutic Significance of Heat Shock Proteins in Cancer.
Neoplasms
Clinical, prognostic, and therapeutic significance of heat shock protein 27 in bladder cancer.
Neoplasms
Clinicopathologic significance of TRAP1 expression in colorectal cancer: a large scale study of human colorectal adenocarcinoma tissues.
Neoplasms
Clinicopathological and biological features of DNA tetraploid colorectal cancers.
Neoplasms
Clinicopathological and genetic characteristics of mucinous carcinomas in the colorectum.
Neoplasms
Clinicopathological and prognostic significance of heat shock protein 27 (HSP27) expression in non-small cell lung cancer: a systematic review and meta-analysis.
Neoplasms
Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma.
Neoplasms
Clusterin as a therapeutic target.
Neoplasms
Clusterin as modulator of carcinogenesis: A potential avenue for targeted cancer therapy.
Neoplasms
Clusterin Inhibition using OGX-011 Synergistically Enhances Hsp90 Inhibitor Activity by Suppressing the Heat Shock Response in Castrate Resistant Prostate Cancer.
Neoplasms
Clusterin mediates TGF-?-induced epithelial-mesenchymal transition and metastasis via Twist1 in prostate cancer cells.
Neoplasms
Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78.
Neoplasms
Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis.
Neoplasms
Co-crystalization and in vitro biological characterization of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole hsp90 inhibitors.
Neoplasms
Co-delivery of TRAIL and siHSP70 using hierarchically modular assembly formulations achieves enhanced TRAIL-resistant cancer therapy.
Neoplasms
Co-segregation of tumor immunogenicity with expression of inducible but not constitutive hsp70 in rat colon carcinomas.
Neoplasms
Codelivery of GRP78 siRNA and docetaxel via RGD-PEG-DSPE/DOPA/CaP nanoparticles for the treatment of castration-resistant prostate cancer.
Neoplasms
Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity.
Neoplasms
Colorectal cancers with microsatellite instability display mRNA expression signatures characteristic of increased immunogenicity.
Neoplasms
Combination of a Selective HSP90?/? Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells.
Neoplasms
Combination of Anti-Cancer Drugs with Molecular Chaperone Inhibitors.
Neoplasms
Combination of apigenin treatment with therapeutic HPV DNA vaccination generates enhanced therapeutic antitumor effects.
Neoplasms
Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice.
Neoplasms
Combination of hyperthermia and bortezomib results in additive killing in mantle cell lymphoma cells.
Neoplasms
Combination of TRAP1 and ERCC1 Expression Predicts Clinical Outcomes in Metastatic Colorectal Cancer Treated with Oxaliplatin/5-Fluorouracil.
Neoplasms
Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose-escalation study.
Neoplasms
Combination of Withaferin-A and CAPE Provides Superior Anticancer Potency: Bioinformatics and Experimental Evidence to Their Molecular Targets and Mechanism of Action.
Neoplasms
Combination radiofrequency (RF) ablation and IV liposomal heat shock protein suppression: Reduced tumor growth and increased animal endpoint survival in a small animal tumor model.
Neoplasms
Combination therapies with HSP90 inhibitors against colorectal cancer.
Neoplasms
Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells.
Neoplasms
Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim.
Neoplasms
Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone.
Neoplasms
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90.
Neoplasms
Combinatorial inhibition of mTORC2 and Hsp90 leads to a distinctly effective therapeutic strategy in malignant pheochromocytom.
Neoplasms
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.
Neoplasms
Combined ?-methylacyl-CoA racemase inhibition and docetaxel treatment reduce cell proliferation and decrease expression of heat shock protein 27 in androgen receptor-variant-7-positive prostate cancer cells.
Neoplasms
Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.
Neoplasms
Combined Effect of Hsp90 Inhibitor Geldanamycin and Parthenolide via Reactive Oxygen Species-Mediated Apoptotic Process on Epithelial Ovarian Cancer Cells.
Neoplasms
Combined effect of tumor necrosis factor (TNF)-alpha and heat shock protein (HSP)-70 in reducing apoptotic injury in hypoxia: a cell culture study.
Neoplasms
Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway.
Neoplasms
Combined effects of mulch film-derived microplastics and atrazine on oxidative stress and gene expression in earthworm (Eisenia fetida).
Neoplasms
Combined HSP90 and kinase inhibitor therapy: Insights from The Cancer Genome Atlas.
Neoplasms
Combined in silico and experimental approach for drug design: the binding mode of peptidic and non-peptidic inhibitors to hsp90 N-terminal domain.
Neoplasms
Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells.
Neoplasms
Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation.
Neoplasms
Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.
Neoplasms
Combined inhibition of Hsp90 and heme oxygenase-1 induces apoptosis and endoplasmic reticulum stress in melanoma.
Neoplasms
Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells.
Neoplasms
Combined lentiviral and RNAi technologies for the delivery and permanent silencing of the hsp25 gene.
Neoplasms
Combined pharmacophore and structure-guided studies to identify diverse HSP90 inhibitors.
Neoplasms
Combined PI3K/Akt and Hsp90 targeting synergistically suppresses essential functions of alloreactive T cells and increases Tregs.
Neoplasms
Combined use of heat-shock protein 70 and glutamine synthetase is useful in the distinction of typical hepatocellular adenoma from atypical hepatocellular neoplasms and well-differentiated hepatocellular carcinoma.
Neoplasms
Combining an Hsp70 inhibitor with either an N- or C-terminal Hsp90 inhibitor produces mechanistically distinct phenotypes.
Neoplasms
Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters. Commentary re: P. Münster et al., Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. Clin. Cancer Res., 7: 2228-2236, 2001.
Neoplasms
Combining GRP78 suppression and MK2206-induced Akt inhibition decreases doxorubicin-induced P-glycoprotein expression and mitigates chemoresistance in human osteosarcoma.
Neoplasms
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone.
Neoplasms
Combining radiation and molecular targeting in cancer therapy.
Neoplasms
Combining Trail with PI3 Kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.
Neoplasms
Commercial Dairy Cow Milk microRNAs Resist Digestion under Simulated Gastrointestinal Tract Conditions.
Neoplasms
Comparative effects of SNX-7081 and SNX-2112 on cell cycle, apoptosis and Hsp90 client proteins in human cancer cells.
Neoplasms
Comparative proteomic analysis for the detection of biomarkers in pancreatic ductal adenocarcinomas.
Neoplasms
Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?
Neoplasms
Comparative study of stress and immune-related transcript outcomes triggered by Vibrio anguillarum bacterin and air exposure stress in liver and spleen of gilthead seabream (Sparus aurata), zebrafish (Danio rerio) and rainbow trout (Oncorhynchus mykiss).
Neoplasms
Comparison of cell cycle components, apoptosis and cytoskeleton-related molecules and therapeutic effects of flavopiridol and geldanamycin on the mouse fibroblast, lung cancer and embryonic stem cells.
Neoplasms
Comparison of inhibitory effect of 17-DMAG nanoparticles and free 17-DMAG in HSP90 gene expression in lung cancer.
Neoplasms
Comparison of inhibitory effects of 17-AAG nanoparticles and free 17-AAG on HSP90 gene expression in breast cancer.
Neoplasms
Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 function.
Neoplasms
Comparison of the expression of 5 heat shock proteins in benign and malignant salivary gland tumor tissues.
Neoplasms
Comparison of the stress response in patients undergoing gynecological laparoscopic surgery using carbon dioxide pneumoperitoneum or abdominal wall-lifting methods.
Neoplasms
Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones.
Neoplasms
Complementary autophagy inhibition and glucose metabolism with rattle-structured polydopamine@mesoporous silica nanoparticles for augmented low-temperature photothermal therapy and in vivo photoacoustic imaging.
Neoplasms
Complex of C60 Fullerene with Doxorubicin as a Promising Agent in Antitumor Therapy.
Neoplasms
Compound ranking based on a new mathematical measure of effectiveness using time course data from cell-based assays.
Neoplasms
Comprehensive review on the HSC70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potential.
Neoplasms
Compromising the constitutive p16INK4a expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence.
Neoplasms
Computational aided mechanistic understanding of Camellia sinensis bioactive compounds against co-chaperone p23 as potential anticancer agent.
Neoplasms
Computational Modeling of the Hsp90 Interactions with Cochaperones and Small-Molecule Inhibitors.
Neoplasms
Computational Polypharmacology Analysis of the Heat Shock Protein 90 Interactome.
Neoplasms
Computational predictions of corroles as a class of Hsp90 inhibitors.
Neoplasms
Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells.
Neoplasms
Conformational dynamics of full-length inducible human Hsp70 derived from microsecond molecular dynamics simulations in explicit solvent.
Neoplasms
Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs.
Neoplasms
Conformational dynamics of the molecular chaperone Hsp90.
Neoplasms
Conjugation with polyamines enhances the antitumor activity of naphthoquinones against human glioblastoma cells.
Neoplasms
Consecutive Day HSP90 Inhibitor Administration Improves Efficacy in Murine Models of KIT-Driven Malignancies and Canine Mast Cell Tumors.
Neoplasms
Consequences of heat shock protein 72 (Hsp72) expression and activity on stress-induced apoptosis in CD30(+) NPM-ALK(+) anaplastic large-cell lymphomas.
Neoplasms
Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors.
Neoplasms
Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis.
Neoplasms
Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.
Neoplasms
Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s.
Neoplasms
Controlled CRISPR-Cas9 Ribonucleoprotein Delivery for Sensitized Photothermal Therapy.
Neoplasms
Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9.
Neoplasms
Cooperative Enhancement of Radiosensitivity After Combined Treatment of 17-(Allylamino)-17-Demethoxygeldanamycin and Celecoxib in Human Lung and Colon Cancer Cell Lines.
Neoplasms
Cooperative Interactions between Androgen Receptor (AR) and Heat-Shock Protein 27 Facilitate AR Transcriptional Activity.
Neoplasms
Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery.
Neoplasms
Coordinated Conformational Processing of the Tumor Suppressor Protein p53 by the Hsp70 and Hsp90 Chaperone Machineries.
Neoplasms
Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex.
Neoplasms
Correction to "CXL146, a Novel 4H-Chromene Derivative, Targets GRP78 to Selectively Eliminate Multidrug-Resistant Cancer Cells".
Neoplasms
Correction to: Reflections and Outlook on Targeting HSP90, HSP70 and HSF1 in Cancer: A Personal Perspective.
Neoplasms
Correction: A Phase I Study of the Heat Shock Protein 90 Inhibitor Alvespimycin (17-DMAG) Given Intravenously to Patients with Advanced Solid Tumors.
Neoplasms
Correction: Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer.
Neoplasms
Correlated fluorescence microscopy and multi-ion beam secondary ion mass spectrometry imaging reveals phosphatidylethanolamine increases in the membrane of cancer cells over-expressing the molecular chaperone subunit CCT?.
Neoplasms
Correlation between clinicopathology and expression of heat shock protein 72 and glycoprotein 96 in human esophageal squamous cell carcinoma.
Neoplasms
Correlation between clinicopathology and expression of heat shock protein 72 and glycoprotein 96 in human gastric adenocarcinoma.
Neoplasms
Correlation between the progressive cytoplasmic expression of a novel small heat shock protein (Hsp16.2) and malignancy in brain tumors.
Neoplasms
Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.
Neoplasms
Correlation of heat shock protein 70 expression with estrogen receptor levels in invasive human breast cancer.
Neoplasms
Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer.
Neoplasms
Correlation of malignant phenotypes of human tumour cell lines with augmented expression of Hsp72 protein measured by laser scanning cytometry.
Neoplasms
Correlation of the protein expression of GRP78 and BIK/NBK with prognostic markers in patients with breast cancer and neoadjuvant chemotherapy.
Neoplasms
Corrigendum: Landscape of the mitochondrial Hsp90 metabolome in tumours.
Neoplasms
Cotargeting HSP90 and Its Client Proteins for Treatment of Prostate Cancer.
Neoplasms
Could the Anti-Chaperone VER155008 Replace Temozolomide for Glioma Treatment.
Neoplasms
Coupling apoptosis resistance to the cellular stress response: the IAP-Hsp90 connection in cancer.
Neoplasms
CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells.
Neoplasms
Cracking the Chaperone Code: Cellular Roles for Hsp70 Phosphorylation.
Neoplasms
Creation of Recombinant Chaperone Vaccine Using Large Heat Shock Protein for Antigen-Targeted Cancer Immunotherapy.
Neoplasms
CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90.
Neoplasms
CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer.
Neoplasms
Cripto haploinsufficiency affects in vivo colon tumor development.
Neoplasms
Cripto stabilizes GRP78 on the cell membrane.
Neoplasms
Critical Role of Mortalin/GRP75 In Endothelial Cell Dysfunction Associated With Acute Lung Injury.
Neoplasms
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.
Neoplasms
Cross-presentation of the oncofoetal tumor antigen 5T4 from irradiated prostate cancer cells - a key role for heat shock protein 70 and receptor CD91.
Neoplasms
Cross-priming of minor histocompatibility antigen-specific cytotoxic T cells upon immunization with the heat shock protein gp96.
Neoplasms
Cryptotanshinone-Induced p53-Dependent Sensitization of Colon Cancer Cells to Apoptotic Drive by Regulation of Calpain and Calcium Homeostasis.
Neoplasms
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Neoplasms
Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex.
Neoplasms
Crystal Structure of the Nucleotide Binding Domain of Mortalin, the mitochondrial Hsp70 chaperone.
Neoplasms
Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitors.
Neoplasms
CUDC-305, a novel synthetic HSP90 inhibitor with unique pharmacologic properties for cancer therapy.
Neoplasms
Curcumin Affects HSP60 Folding Activity and Levels in Neuroblastoma Cells.
Neoplasms
Curcumin and Glu-GNPs Induce Radiosensitivity against Breast Cancer Stem-Like Cells.
Neoplasms
Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1.
Neoplasms
Curcumin suppresses proliferation and invasion in non-small cell lung cancer by modulation of MTA1-mediated Wnt/?-catenin pathway.
Neoplasms
Current Strategies to Overcome Resistance to ALK-Inhibitor Agents.
Neoplasms
Current Understanding of HSP90 as a Novel Therapeutic Target: An Emerging Approach for the Treatment of Cancer.
Neoplasms
Cutting edge: tumor secreted heat shock-fusion protein elicits CD8 cells for rejection.
Neoplasms
CXL146, a Novel 4H-Chromene Derivative, Targets GRP78 to Selectively Eliminate Multidrug-Resistant Cancer Cells.
Neoplasms
Cyclophosphamide inhibits the progression of Meniere's disease by reducing the generation of circulating immune complex.
Neoplasms
Cysteine Proteases from V. cundinamarcensis (C. candamarcensis) Inhibit Melanoma Metastasis and Modulate Expression of Proteins Related to Proliferation, Migration and Differentiation.
Neoplasms
Cytokine and adhesion molecule expression in human monocytes and endothelial cells stimulated with bacterial heat shock proteins.
Neoplasms
Cytokine synthesis in the liver of endotoxin-tolerant and normal rats during hemorrhagic shock.
Neoplasms
Cytokines, Chaperones and Neuroinflammatory Responses in Heroin-Related Death: What Can We Learn from Different Patterns of Cellular Expression?
Neoplasms
Cytoplasmic sequestration of the tumor suppressor p53 by a heat shock protein 70 family member, mortalin, in human colorectal adenocarcinoma cell lines.
Neoplasms
Cytoprotection and regulation of heat shock proteins induced by heat shock in human breast cancer T47-D cells: role of [Ca2+]i and protein kinases.
Neoplasms
Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer.
Neoplasms
Cytosolic Hsp60 is involved in the NF-kappaB-dependent survival of cancer cells via IKK regulation.
Neoplasms
Cytosolic-nuclear tumor promoter-specific binding protein: association with the 90 kDa heat shock protein and translocation into nuclei by treatment with 12-O-tetradecanoylphorbol 13-acetate.
Neoplasms
Cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90.
Neoplasms
Cytotoxic T cell responses against mesothelioma by apoptotic cell-pulsed dendritic cells.
Neoplasms
Cytotoxic T lymphocyte recognition of non-Hodgkin's B cell lymphomas.
Neoplasms
DCZ3112, a novel Hsp90 inhibitor, exerts potent antitumor activity against HER2-positive breast cancer through disruption of Hsp90-Cdc37 interaction.
Neoplasms
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer.
Neoplasms
Death by chaperone: HSP90, HSP70 or both?
Neoplasms
Debio-0932, a second generation oral Hsp90 inhibitor, induces apoptosis in MCF-7 and MDA-MB-231 cell lines.
Neoplasms
Deciphering the Inhibition Mechanism of under Trial Hsp90 Inhibitors and Their Analogues: A Comparative Molecular Dynamics Simulation.
Neoplasms
Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas.
Neoplasms
Decrease of heat shock protein levels and cell populations by wine phenolic extracts.
Neoplasms
Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan.
Neoplasms
Definition of extracellular localized epitopes of Hsp70 involved in an NK immune response.
Neoplasms
Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
Neoplasms
Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity.
Neoplasms
Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks.
Neoplasms
Demethoxycurcumin: A naturally occurring curcumin analogue with antitumor properties.
Neoplasms
Demonstration of selective protein complexes of p53 with 73 kDa heat shock cognate protein, but not with 72 kDa heat shock protein in human tumor cells.
Neoplasms
Dendritic cells combined with doxorubicin induces immunogenic cell death and exhibits antitumor effects for osteosarcoma.
Neoplasms
Dendritic-tumor fusion cells derived heat shock protein70-peptide complex has enhanced immunogenicity.
Neoplasms
Deoxyribonuclease 1-Mediated Clearance of Circulating Chromatin Prevents From Immune Cell Activation and Pro-inflammatory Cytokine Production, a Phenomenon Amplified by Low Trap1 Activity: Consequences for Systemic Lupus Erythematosus.
Neoplasms
Dephosphorylation of the small heat shock protein hsp25 by calcium/calmodulin-dependent (type 2B) protein phosphatase.
Neoplasms
Design and biological testing of peptidic dimerization inhibitors of human Hsp90 that target the C-terminal domain.
Neoplasms
Design and synthesis of Grp94 selective inhibitors based on Phe199 induced fit mechanism and their anti-inflammatory effects.
Neoplasms
Design and synthesis of neolamellarin a derivatives targeting heat shock protein 90.
Neoplasms
Design and synthesis of piperidine derivatives as novel human heat shock protein 70 inhibitors for the treatment of drug-resistant tumors.
Neoplasms
Design and synthesis of pyrimidinyl acyl thioureas as novel Hsp90 inhibitors in invasive ductal breast cancer and its bone metastasis.
Neoplasms
Design of Disruptors of the Hsp90-Cdc37 Interface.
Neoplasms
Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.
Neoplasms
Design, synthesis and bioevaluation of inhibitors targeting HSP90-CDC37 protein-protein interaction based on a hydrophobic core.
Neoplasms
Design, synthesis and biological evaluation of alkylamino biphenylamides as Hsp90 C-terminal inhibitors.
Neoplasms
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors.
Neoplasms
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3K?) against cutaneous melanoma.
Neoplasms
Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response.
Neoplasms
Design, synthesis, and biological evaluation of a series of resorcinol-based N-benzyl benzamide derivatives as potent Hsp90 inhibitors.
Neoplasms
Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.
Neoplasms
Design, synthesis, and biological evaluation of ring-constrained novobiocin analogues as hsp90 C-terminal inhibitors.
Neoplasms
Design, synthesis, and evaluation of small molecule Hsp90 probes.
Neoplasms
Design, synthesis, and molecular docking studies of novel pyrazolyl 2-aminopyrimidine derivatives as HSP90 inhibitors.
Neoplasms
Design, synthesis, and structure-activity relationships for chimeric inhibitors of hsp90.
Neoplasms
Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.
Neoplasms
Destabilization of ROR1 enhances activity of Ibrutinib against chronic lymphocytic leukemia in vivo.
Neoplasms
Destabilization of the Epidermal Growth Factor Receptor (EGFR) by a Peptide That Inhibits EGFR Binding to Heat Shock Protein 90 and Receptor Dimerization.
Neoplasms
Detecting the Potential Pharmacological Synergy of Drug Combination by Viability Assays In Vitro.
Neoplasms
Detection of cathepsin B up-regulation in neoplastic thyroid tissues by proteomic analysis.
Neoplasms
Detection of irradiation-induced, membrane heat shock protein 70 (Hsp70) in mouse tumors using Hsp70 Fab fragment.
Neoplasms
Detection of the ATPase activity of the molecular chaperones Hsp90 and Hsp72 using the TranscreenerTM ADP assay kit.
Neoplasms
Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections.
Neoplasms
Determining the neuroprotective effects of dextromethorphan in lipopolysaccharide?stimulated BV2 microglia.
Neoplasms
Development and application of Hsp90 inhibitors.
Neoplasms
Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.
Neoplasms
Development and optimization of a useful assay for determining Hsp90's inherent ATPase activity.
Neoplasms
Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.
Neoplasms
Development of a Bifunctional Andrographolide-Based Chemical Probe for Pharmacological Study.
Neoplasms
Development of a biosensor platform based on ITO sheets modified with 3-glycidoxypropyltrimethoxysilane for early detection of TRAP1.
Neoplasms
Development of a Cell-Based Ligand-Screening System for Identifying Hsp90 Inhibitors.
Neoplasms
Development of a fluorescence polarization assay for the molecular chaperone Hsp90.
Neoplasms
Development of a Grp94 inhibitor.
Neoplasms
Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors.
Neoplasms
Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1.
Neoplasms
Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase.
Neoplasms
Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors.
Neoplasms
Development of noviomimetics that modulate molecular chaperones and manifest neuroprotective effects.
Neoplasms
Development of Novobiocin Analogues That Manifest Anti-proliferative Activity against Several Cancer Cell Lines.
Neoplasms
Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C-terminal Inhibitors.
Neoplasms
Development of purine-scaffold small molecule inhibitors of Hsp90.
Neoplasms
Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models.
Neoplasms
Development of radicicol analogues.
Neoplasms
Development of small molecule Hsp90 inhibitors: utilizing both forward and reverse chemical genomics for drug identification.
Neoplasms
DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines.
Neoplasms
Diabetes mellitus in cystic fibrosis: genetic and immunological markers.
Neoplasms
Diagnostic and prognostic value of heat shock protein 90? in malignant melanoma.
Neoplasms
Diagnostic management of benign and malignant pheochromocytoma.
Neoplasms
Diagnostic Value of Glypican3, Heat Shock Protein 70 and Glutamine Synthetase in Hepatocellular Carcinoma Arising in Cirrhotic and Non-Cirrhotic Livers.
Neoplasms
Diagnostic value of plasma HSP90? levels for detection of hepatocellular carcinoma.
Neoplasms
Diagnostic, clinicopathologic, therapeutic and prognostic value of Plasma Heat Shock Protein 90 levels in patients with advanced Gastrointestinal Carcinoma.
Neoplasms
Dibutyryl cyclic adenosine monophosphate protects mice against tumor necrosis factor-alpha-induced hepatocyte apoptosis accompanied by increased heat shock protein 70 expression.
Neoplasms
Dicoumarol down-regulates human PTTG1/Securin mRNA expression through inhibition of Hsp90.
Neoplasms
Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via ?-catenin/ABCG2 signaling.
Neoplasms
Dietary garlic and chitosan enhanced the antioxidant capacity, immunity, and modulated the transcription of HSP70 and Cytokine genes in Zearalenone-intoxicated European seabass.
Neoplasms
Dietary resistant starch type 3 prevents tumor induction by 1,2-dimethylhydrazine and alters proliferation, apoptosis and dedifferentiation in rat colon.
Neoplasms
Dietary supplemental microalgal astaxanthin modulates molecular profiles of stress, inflammation, and lipid metabolism in broiler chickens and laying hens under high ambient temperatures.
Neoplasms
Dietary supplementation of black mulberry (Morus nigra) syrup improves the growth performance, innate immune response, antioxidant status, gene expression responses, and disease resistance of Nile tilapia (Oreochromis niloticus).
Neoplasms
Dietary therapeutic dose of oxytetracycline negatively influences the antioxidant capacity and immune-related genes expression in Nile tilapia Oreochromis niloticus (L.).
Neoplasms
Diferuloylmethane augments the cytotoxic effects of piplartine isolated from Piper chaba.
Neoplasms
Differences in glycosylation patterns of heat shock protein, gp96: implications for prostate cancer prevention.
Neoplasms
Different concentrations of two small stress proteins, alphaB crystallin and HSP27 in human urological tumor tissues.
Neoplasms
Different effect of glutamine on macrophage tumor necrosis factor-alpha release and heat shock protein 72 expression in vitro and in vivo.
Neoplasms
Different expression of CD44, ICAM-1, and HSP60 on primary tumor and metastases of a human pancreatic carcinoma growing in scid mice.
Neoplasms
Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis.
Neoplasms
Different responses of apoptotic, inflammatory and heat shock protein gene expression to a single bout of high-intensity interval exercise between physically active and inactive men.
Neoplasms
Differential effect of acute and permanent heat shock protein 70 overexpression in tumor cells on lysability by cytotoxic T lymphocytes.
Neoplasms
Differential expression of alphaB-crystallin and Hsp27-1 in anaplastic thyroid carcinomas because of tumor-specific alphaB-crystallin gene (CRYAB) silencing.
Neoplasms
Differential Expression of Heat Shock Protein 27 in Oral Epithelial Dysplasias and Squamous Cell Carcinoma.
Neoplasms
Differential expression of heat shock protein 70 (hsp70) in human monocytes rendered apoptotic by IL-4 or serum deprivation.
Neoplasms
Differential expression of heat shock protein 90 isoforms in small cell lung cancer.
Neoplasms
Differential expression of HSP90 isoforms and their correlations with clinicopathologic factors in patients with colorectal cancer.
Neoplasms
Differential expression of immune system-related components in midtrimester amniotic fluid from singleton and twin pregnancies.
Neoplasms
Differential expression of Janus kinase 3 (JAK3), matrix metalloproteinase 13 (MMP13), heat shock protein 60 (HSP60), and mouse double minute 2 (MDM2) in human colorectal cancer progression using human cancer cDNA microarrays.
Neoplasms
Differential heat shock protein localization in chronic lymphocytic leukemia.
Neoplasms
Differential influence of anticancer treatments and angiogenesis on the seric titer of autoantibody used as tumor and metastasis biomarker.
Neoplasms
Differential mitochondrial proteome analysis of human lung adenocarcinoma and normal bronchial epithelium cell lines using quantitative mass spectrometry.
Neoplasms
Differential MyD88/IRAK4 requirements for cross-priming and tumor rejection induced by heat shock protein 70-model antigen fusion protein.
Neoplasms
Differential protein expression in primary breast cancer and matched axillary node metastasis.
Neoplasms
Differential protein expression using proteomics from a crustacean brine shrimp (Artemia sinica) under CO2-driven seawater acidification.
Neoplasms
Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen.
Neoplasms
Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs.
Neoplasms
Differential up-regulation of HLA-DM, invariant chain, and CD83 on myeloid and plasmacytoid dendritic cells from peripheral blood.
Neoplasms
Differentially expressed genes associated with human lung cancer.
Neoplasms
Differentially expressed genes in asbestos-induced tumorigenic human bronchial epithelial cells: implication for mechanism.
Neoplasms
Differentially expressed soluble proteins in aortic cells from atherosclerosis-susceptible and resistant pigeons.
Neoplasms
Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives.
Neoplasms
Diosgenin inhibits tumor angiogenesis through regulating GRP78-mediated HIF-1? and VEGF/VEGFR signaling pathways.
Neoplasms
Direct regulation of HSP60 expression by c-MYC induces transformation.
Neoplasms
Discorhabdin N, a South African Natural Compound, for Hsp72 and Hsc70 Allosteric Modulation: Combined Study of Molecular Modeling and Dynamic Residue Network Analysis.
Neoplasms
Discovering High Potent Hsp90 Inhibitors as Antinasopharyngeal Carcinoma Agents through Fragment Assembling Approach.
Neoplasms
Discovery and Bioevaluation of Novel Pyrazolopyrimidine Analogs as Competitive Hsp90 Inhibitors Through Shape-Based Similarity Screening.
Neoplasms
Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
Neoplasms
Discovery and development of heat shock protein 90 inhibitors.
Neoplasms
Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy.
Neoplasms
Discovery and development of purine-scaffold Hsp90 inhibitors.
Neoplasms
Discovery and development of pyrazole-scaffold Hsp90 inhibitors.
Neoplasms
Discovery and optimization of 4,5-diarylisoxazoles as potent dual inhibitors of pyruvate dehydrogenase kinase and heat shock protein 90.
Neoplasms
Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.
Neoplasms
Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug design.
Neoplasms
Discovery of (2S)-1-[4-(2-{6-Amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a Purine-Based Hsp90 Inhibitor.
Neoplasms
Discovery of 2',4'-dimethoxychalcone as a Hsp90 inhibitor and its effect on iressa-resistant non-small cell lung cancer (NSCLC).
Neoplasms
Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1.
Neoplasms
Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1 H-pyrazol-4-yl)-1 H-imidazol-1-yl)-1 H-pyrazolo[3,4- b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor.
Neoplasms
Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.
Neoplasms
Discovery of a covalent inhibitor of heat shock protein 90 with antitumor activity that blocks the co-chaperone binding via C-terminal modification.
Neoplasms
Discovery of a Potent Grp94 Selective Inhibitor with Anti-Inflammatory Efficacy in a Mouse Model of Ulcerative Colitis.
Neoplasms
Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model.
Neoplasms
Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling.
Neoplasms
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90.
Neoplasms
Discovery of hybrid Hsp90 inhibitors and their anti-neoplastic effects against gefitinib-resistant non-small cell lung cancer (NSCLC).
Neoplasms
Discovery of new heat shock protein 90 inhibitors using virtual co-crystallized pharmacophore generation.
Neoplasms
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain.
Neoplasms
Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90).
Neoplasms
Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents.
Neoplasms
Discovery of novel anti-breast cancer agents derived from deguelin as inhibitors of heat shock protein 90 (HSP90).
Neoplasms
Discovery of novel Hsp90 C-terminal domain inhibitors that disrupt co-chaperone binding.
Neoplasms
Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations.
Neoplasms
Discovery of novel NO-releasing celastrol derivatives with Hsp90 inhibition and cytotoxic activities.
Neoplasms
Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Neoplasms
Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors.
Neoplasms
Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy.
Neoplasms
Discovery of structure-based small molecular inhibitor of ?B-crystallin against basal-like/triple-negative breast cancer development in vitro and in vivo.
Neoplasms
Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation.
Neoplasms
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis.
Neoplasms
Distal intestinal gene expression in Atlantic salmon (Salmo salar L.) fed genetically modified maize
Neoplasms
Distinct regulation of insulin receptor substrate-1 and -2 by 90-kDa heat-shock protein in adrenal chromaffin cells.
Neoplasms
Divergent effects of castration on prostate cancer in TRAMP mice: possible implications for therapy.
Neoplasms
DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy.
Neoplasms
DNA vaccine encoding heat shock protein 60 co-linked to HPV16 E6 and E7 tumor antigens generates more potent immunotherapeutic effects than respective E6 or E7 tumor antigens.
Neoplasms
DNA-templated porous nanoplatform towards programmed "double-hit" cancer therapy via hyperthermia and immunogenicity activation.
Neoplasms
Dnajb8, a Member of the Heat Shock Protein 40 Family Has a Role in the Tumor Initiation and Resistance to Docetaxel but Is Dispensable for Stress Response.
Neoplasms
Docosahexaenoic acid in combination with celecoxib modulates HSP70 and p53 proteins in prostate cancer cells.
Neoplasms
Docosahexaenoic Acid-mediated Inhibition of Heat Shock Protein 90-p23 Chaperone Complex and Downstream Client Proteins in Lung and Breast Cancer.
Neoplasms
Does the compromised sleep and circadian disruption of night and shiftworkers make them highly vulnerable to 2019 coronavirus disease (COVID-19)?
Neoplasms
Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels.
Neoplasms
Dose-escalation study of a second-generation non-ansamycin HSP90 inhibitor, onalespib (AT13387), in combination with imatinib in patients with metastatic gastrointestinal stromal tumour.
Neoplasms
Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells.
Neoplasms
Down-regulation of HSP40 gene family following OCT4B1 suppression in human tumor cell lines.
Neoplasms
Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells.
Neoplasms
Down-regulation of topoisomerase II alpha is caused by up-regulation of GRP78.
Neoplasms
Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma.
Neoplasms
Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence.
Neoplasms
Dried lemon peel enriched diet improves antioxidant activity, immune response and modulates immuno-antioxidant genes in Labeo rohita against Aeromonas sorbia.
Neoplasms
Drug design, synthesis and in vitro evaluation of substituted benzofurans as Hsp90 inhibitors.
Neoplasms
Drug evaluation: STA-4783--enhancing taxane efficacy by induction of Hsp70.
Neoplasms
Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers.
Neoplasms
Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.
Neoplasms
Druggability of Mortalin for Cancer and Neuro-Degenerative Disorders.
Neoplasms
Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress.
Neoplasms
DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90.
Neoplasms
Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug.
Neoplasms
Dual drug-paired polyprodrug nanotheranostics reverse multidrug resistant cancers via mild photothermal-cocktail chemotherapy.
Neoplasms
Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells.
Neoplasms
Dual inhibition of chaperoning process by taxifolin: molecular dynamics simulation study.
Neoplasms
Dual mode of cancer cell destruction for pancreatic cancer therapy using Hsp90 inhibitor loaded polymeric nano magnetic formulation.
Neoplasms
Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
Neoplasms
Dual role of heat shock proteins as regulators of apoptosis and innate immunity.
Neoplasms
Dual systemic tumor targeting with ligand-directed phage and Grp78 promoter induces tumor regression.
Neoplasms
Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis.
Neoplasms
Dual targeting of HSP70 does not induce the heat shock response and synergistically reduces cell viability in muscle invasive bladder cancer.
Neoplasms
Dual Targeting Strategies On Histone Deacetylase 6 (HDAC6) And Heat Shock Protein 90 (Hsp90).
Neoplasms
Dual-Channel Theranostic System for Quantitative Self-Indication and Low-Temperature Synergistic Therapy of Cancer.
Neoplasms
Dual-targeting of mTOR and HSP90 for cancer therapy: Facing oncogenic feed-back-loops and acquired mTOR resistance.
Neoplasms
Dynamic changes in gene expression during vitellogenic stages of the white shrimp: Fenneropenaeus merguiensis de Man
Neoplasms
Dynamic effect of heat shock pretreatment on apoptotic responses to TNF-alpha in liver cells.
Neoplasms
Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapy.
Neoplasms
Dynamic proteomics reveals bimodal protein dynamics of cancer cells in response to HSP90 inhibitor.
Neoplasms
Dynamically Shaping Chaperones. Allosteric Modulators of HSP90 Family as Regulatory Tools of Cell Metabolism in Neoplastic Progression.
Neoplasms
Dynamics-Based Discovery of Allosteric Inhibitors: Selection of New Ligands for the C-terminal Domain of Hsp90.
Neoplasms
E3 ubiquitin ligase Cullin-5 modulates multiple molecular and cellular responses to heat shock protein 90 inhibition in human cancer cells.
Neoplasms
Early and Synergistic Recovery Effect of Herbal Combination on Surgically Corrected Varicocele.
Neoplasms
Early cytotoxic effects of ochratoxin A in rat liver: a morphological, biochemical and molecular study.
Neoplasms
Early development of PAT-SM6 for the treatment of melanoma.
Neoplasms
Early tumor response to Hsp90 therapy using HER2 PET: comparison with 18F-FDG PET.
Neoplasms
EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity.
Neoplasms
Effect of antiangiogenic therapy on luciferase activity in a cytomegalovirus- or HSP70-promoter-transfected M21 tumor model.
Neoplasms
Effect of glutamate on lysosomal membrane permeabilization in primary cultured cortical neurons.
Neoplasms
Effect of heat shock on susceptibility of normal lymphoblasts and of a heat shock protein 70-defective tumour cell line to cytotoxic T lymphocytes in vitro.
Neoplasms
Effect of heat shock protein 90 (Hsp90) on migration and invasion of human cancer cells in vitro.
Neoplasms
Effect of heat stress on LPS-induced febrile response in D-galactosamine-sensitized rats.
Neoplasms
Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models.
Neoplasms
Effect of HSP90AB1 and CC domain interaction on Bcr-Abl protein cytoplasm localization and function in chronic myeloid leukemia cells.
Neoplasms
Effect of hyperthermic CO2-treated dendritic cell-derived exosomes on the human gastric cancer AGS cell line.
Neoplasms
Effect of inhibitors of poly(ADP-ribose) polymerase on the induction of GRP78 and subsequent development of resistance to etoposide.
Neoplasms
Effect of novobiocin on the viability of human gingival fibroblasts (HGF-1).
Neoplasms
Effect of overexpression of glucose-regulated protein 78 and bcl-2 on recurrence and survival in patients with ureter tumors.
Neoplasms
Effect of overexpression of the small heat shock protein HSP27 on the heat and drug sensitivities of human testis tumor cells.
Neoplasms
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Neoplasms
Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats.
Neoplasms
Effect of social housing condition on heat shock protein (HSP) expression in the Shionogi mouse mammary carcinoma (SC115).
Neoplasms
Effectiveness of hsp90 inhibitors as anti-cancer drugs.
Neoplasms
Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.
Neoplasms
Effects of acupuncture at Baihui (DU20) and Zusanli (ST36) on the expression of heat shock protein 70 and tumor necrosis factor ? in the peripheral serum of cerebral ischemia-reperfusion-injured rats.
Neoplasms
Effects of antimicrobial peptides on serum biochemical parameters, antioxidant activity and non-specific immune responses in Epinephelus coioides.
Neoplasms
Effects of Bacillus subtilis WB60 and Lactococcus lactis on Growth, Immune Responses, Histology and Gene Expression in Nile tilapia, Oreochromis niloticus.
Neoplasms
Effects of chito-oligosaccharides supplementation on growth performance, intestinal cytokine expression, autochthonous gut bacteria and disease resistance in hybrid tilapia Oreochromis niloticus ? × Oreochromis aureus ?.
Neoplasms
Effects of chronic nitrate exposure on the intestinal morphology, immune status, barrier function, and microbiota of juvenile turbot (Scophthalmus maximus).
Neoplasms
Effects of ciprofloxacin exposure on the earthworm Eisenia fetida.
Neoplasms
Effects of combination of melatonin and laser irradiation on ovarian cancer cells and endothelial lineage viability.
Neoplasms
Effects of dietary Allium mongolicum Regel polysaccharide on growth, lipopolysaccharide-induced antioxidant responses and immune responses in Channa argus.
Neoplasms
Effects of dietary anthocyanin on innate immune parameters, gene expression responses, and ammonia resistance of Nile tilapia (Oreochromis niloticus).
Neoplasms
Effects of dietary manipulation on compensatory growth of juvenile genetically improved farmed tilapia (Oreochromis niloticus).
Neoplasms
Effects of dietary monoterpene, myrcene, administration on immune- and health-related genes expression in common carp gill following exposure to copper sulfate.
Neoplasms
Effects of Ergosan on the expression of cytokine genes in the liver of juvenile rainbow trout (Oncorhynchus mykiss) exposed to enteric red mouth vaccine.
Neoplasms
Effects of glutamine supplementation on muscle function and stress responses in a mouse model of spinal cord injury.
Neoplasms
Effects of heat stress on the level of heat shock protein 70 on the surface of hepatocellular carcinoma Hep G2 cells: implications for the treatment of tumors.
Neoplasms
Effects of HSP70 on the compression force-induced TNF-? and RANKL expression in human periodontal ligament cells.
Neoplasms
Effects of Hsp90 inhibition in neuroblastoma: analysis of drug sensitivity, target modulation and the influence of bone marrow microenvironment.
Neoplasms
Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy.
Neoplasms
Effects of Hsp90 inhibitor on the RIP1-RIP3-MLKL pathway during the development of heart failure in mice.
Neoplasms
Effects of Molybdenum or/and Cadmium on mRNA Expression Levels of Inflammatory Cytokines and HSPs in Duck Spleens.
Neoplasms
Effects of nontoxic heat shock protein 90 inhibitor peptide derivatives on reversal of MDR of tumor cells.
Neoplasms
Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice.
Neoplasms
Effects of quercetin and sunphenon on responses of cancer cells to heat shock damage.
Neoplasms
Effects of Resistance Training at Different Loads on Inflammatory Biomarkers, Muscle Mass, Muscular Strength, and Physical Performance in Postmenopausal Women.
Neoplasms
Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer.
Neoplasms
Effects of the antimicrobial peptide LL-37 and hyperthermic preconditioning in septic rats.
Neoplasms
Effects of treatment with an Hsp90 inhibitor in tumors based on 15 phase II clinical trials.
Neoplasms
Efficacy and safety of TAS-116, an oral inhibitor of heat shock protein 90, in patients with metastatic or unresectable gastrointestinal stromal tumour refractory to imatinib, sunitinib and regorafenib: a phase II, single-arm trial.
Neoplasms
Efficacy of an EGFR-Specific Peptide against EGFR-Dependent Cancer Cell Lines and Tumor Xenografts.
Neoplasms
Efficacy of an HSP90 inhibitor, ganetespib, in preclinical thyroid cancer models.
Neoplasms
Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
Neoplasms
Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population.
Neoplasms
Elaborate ligand-based modeling reveals new nanomolar heat shock protein 90? inhibitors.
Neoplasms
Elaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity.
Neoplasms
Elevated concentrations of the small stress protein HSP27 in rat renal tumors.
Neoplasms
Elevated expression of nuclear Hsp90 in invasive breast tumors.
Neoplasms
Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer.
Neoplasms
Elevated levels of HSF1 indicate a poor prognosis in breast cancer.
Neoplasms
Elevated levels of mitochondrial mortalin and cytosolic HSP70 in blood as risk factors in patients with colorectal cancer.
Neoplasms
Elevated levels of mortalin expression in human brain tumors.
Neoplasms
Elevated Mortalin correlates with poor outcome in hepatocellular carcinoma.
Neoplasms
Elevated risks for amyotrophic lateral sclerosis and blood disorders in Ashkenazi schizophrenic pedigrees suggest new candidate genes in schizophrenia.
Neoplasms
Elevated serum levels of heat shock protein 70 can be detected after radiofrequency ablation.
Neoplasms
Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling.
Neoplasms
Elucidation of antiangiogenic potential of Vitexin obtained from Cucumis sativus targeting Hsp90 protein: A novel multipathway targeted approach to restrain angiogenic phenomena.
Neoplasms
Emergence of resistance to tyrosine kinase inhibitors in non-small-cell lung cancer can be delayed by an upfront combination with the HSP90 inhibitor onalespib.
Neoplasms
Emerging Hsp90 inhibitors: from discovery to clinic.
Neoplasms
Emerging Roles of Extracellular Hsp90 in Cancer.
Neoplasms
Emerging roles of HSF1 in cancer: Cellular and molecular episodes.
Neoplasms
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Neoplasms
Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin.
Neoplasms
Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis.
Neoplasms
Endogenous tumor necrosis factor promotes resistance to cellular stresses by inducing the metallothionein-1A gene.
Neoplasms
Endogenous tumour necrosis factor regulates heat-inducible heat shock protein 72 synthesis.
Neoplasms
Endoplasmic reticulum chaperone glucose regulated protein 170-Pokemon complexes elicit a robust antitumor immune response in vivo.
Neoplasms
Endoplasmic reticulum chaperone glucose-regulated protein 78 in gastric cancer: An emerging biomarker.
Neoplasms
Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.
Neoplasms
Endoplasmic reticulum heat shock protein gp96/grp94 is a pro-oncogenic chaperone, not a tumor suppressor.
Neoplasms
Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78.
Neoplasms
Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro.
Neoplasms
Endoplasmic reticulum stress confers 5-fluorouracil resistance in breast cancer cell via the GRP78/OCT4/lncRNA MIAT/AKT pathway.
Neoplasms
Endoplasmic reticulum stress is activated in endometrial adenocarcinoma.
Neoplasms
Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport.
Neoplasms
Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor alpha release by murine macrophages.
Neoplasms
Engineered production of kitasetalic acid, a new tetrahydro-?-carboline with the ability to suppress glucose-regulated protein synthesis.
Neoplasms
Engineered Tumor-Derived Extracellular Vesicles: Potentials in Cancer Immunotherapy.
Neoplasms
Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.
Neoplasms
Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer.
Neoplasms
Enhanced antitumor immunity of nanoliposome-encapsulated heat shock protein 70 peptide complex derived from dendritic tumor fusion cells.
Neoplasms
Enhanced cell killing induced by the combination of radiation and the heat shock protein 90 inhibitor 17-allylamino-17- demethoxygeldanamycin: a multitarget approach to radiosensitization.
Neoplasms
Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells.
Neoplasms
Enhanced in vivo antitumor efficacy of dual-functional peptide-modified docetaxel nanoparticles through tumor targeting and Hsp90 inhibition.
Neoplasms
Enhanced sensitivity to mitomycin C by abating heat shock protein 70 expression in human bladder cancer cell line of BIU-87.
Neoplasms
Enhanced suicide gene therapy by chimeric tumor-specific promoter based on HSF1 transcriptional regulation.
Neoplasms
Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Neoplasms
Enhanced synergism of thermo-chemotherapy by combining highly efficient magnetic hyperthermia with magnetothermally-facilitated drug release.
Neoplasms
Enhanced T-cell immunity induced by dendritic cells with phagocytosis of heat shock protein 70 gene-transfected tumor cells in early phase of apoptosis.
Neoplasms
Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin.
Neoplasms
Enhanced ubiquitinylation of heat shock protein 90 as a potential mechanism for mitotic cell death in cancer cells induced with hypericin.
Neoplasms
Enhancement of complement-induced cell lysis: a novel mechanism for the anticancer effects of Hsp90 inhibitors.
Neoplasms
Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X.
Neoplasms
Enhancing HSP70-ShRNA transfection in 22RV1 prostate cancer cells by combination of sonoporation, liposomes and HTERT/CMV chimeric promoter.
Neoplasms
Enhancing therapeutic HPV DNA vaccine potency through depletion of CD4+CD25+ T regulatory cells.
Neoplasms
Environmental stress and genes of hypertension.
Neoplasms
Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo.
Neoplasms
Epithelial-to-mesenchymal transition: immunohistochemical investigation of related molecules in canine cutaneous epithelial tumours.
Neoplasms
ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness".
Neoplasms
ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma.
Neoplasms
Eradication of glioblastoma, and breast and colon carcinoma xenografts by Hsp70 depletion.
Neoplasms
Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter.
Neoplasms
ErbB3 expression predicts tumor cell radiosensitization induced by Hsp90 inhibition.
Neoplasms
Ergothioneine modulates proinflammatory cytokines and heat shock protein 70 in mesenteric ischemia and reperfusion injury.
Neoplasms
ERK-dependent phosphorylation of the linker and substrate-binding domain of HSP70 increases folding activity and cell proliferation.
Neoplasms
ERK-regulated ?B-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo.
Neoplasms
ERO1?-dependent endoplasmic reticulum-mitochondrial calcium flux contributes to ER stress and mitochondrial permeabilization by procaspase-activating compound-1 (PAC-1).
Neoplasms
Erratum to: Novel C-terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents.
Neoplasms
Erratum: Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer.
Neoplasms
Erythroid Differentiation Regulator 1, an Interleukin 18-Regulated Gene, Acts as a Metastasis Suppressor in Melanoma.
Neoplasms
Erythropoietin prevents the effect of chronic restraint stress on the number of hippocampal CA3c dendritic terminals-relation to expression of genes involved in synaptic plasticity, angiogenesis, inflammation, and oxidative stress in male rats.
Neoplasms
Erythropoietin receptors on tumor cells: what do they mean?
Neoplasms
Essential oil from Cymbopogon flexuosus as the potential inhibitor for HSP90.
Neoplasms
Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90.
Neoplasms
Establishment of a spontaneous metastasis tumor model for human ErbB-2 vaccine.
Neoplasms
Estrogen receptor gene expression and its relation to the estrogen-inducible HSP27 heat shock protein in hormone refractory prostate cancer.
Neoplasms
Estrogen receptor, progesterone receptor, and HER-2/neu protein in breast cancers from pregnant patients.
Neoplasms
Estrogen receptor-?36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
Neoplasms
Estrogen-induced genes in the uterus of ovariectomized rats and their regulation by droloxifene and tamoxifen.
Neoplasms
Ethnic differences of polymorphisms in cytokine and innate immune system genes in pregnant women.
Neoplasms
Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator.
Neoplasms
Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.
Neoplasms
Evaluation of anti-tumor effects of tumor cell lysate enriched by HSP-70 against fibrosarcoma tumor in BALB/c mice.
Neoplasms
Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer.
Neoplasms
Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110.
Neoplasms
Evaluation of the Hsp90 inhibitor NVP-AUY922 in multicellular tumour spheroids with respect to effects on growth and PET tracer uptake.
Neoplasms
Evaluation of the radiosensitizing potency of chemotherapeutic agents in prostate cancer cells.
Neoplasms
Evaluation of [11C]NMS-E973 as a PET tracer for in vivo visualisation of HSP90.
Neoplasms
Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors.
Neoplasms
Evidence of a Cell Surface Role for Hsp90 Complex Proteins Mediating Neuroblast Migration in the Subventricular Zone.
Neoplasms
Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas.
Neoplasms
Evodiamine inhibits both stem cell and non-stem-cell populations in human cancer cells by targeting heat shock protein 70.
Neoplasms
Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression.
Neoplasms
Ex vivo Hsp70-Activated NK Cells in Combination With PD-1 Inhibition Significantly Increase Overall Survival in Preclinical Models of Glioblastoma and Lung Cancer.
Neoplasms
Exercise Training Attenuates Neuropathic Pain and Cytokine Expression After Chronic Constriction Injury of Rat Sciatic Nerve.
Neoplasms
Exercise, vascular wall and cardiovascular diseases: an update (Part 1).
Neoplasms
Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
Neoplasms
Exogenous heat shock protein 27 uniquely blocks differentiation of monocytes to dendritic cells.
Neoplasms
Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, angiopoiesis and migration effects via activating HSP90 pathway in EC109 cells.
Neoplasms
Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity.
Neoplasms
Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity.
Neoplasms
Exosomal formulation enhances therapeutic response of celastrol against lung cancer.
Neoplasms
Exosomal HSP60: a potentially useful biomarker for diagnosis, assessing prognosis, and monitoring response to treatment.
Neoplasms
Exosomes Based Geldanamycin Delivery to Cancer Cells with Increased Therapeutic Efficacy.
Neoplasms
Exosomes derived from siRNA against GRP78 modified bone-marrow-derived mesenchymal stem cells suppress Sorafenib resistance in hepatocellular carcinoma.
Neoplasms
Exosomes from heat-stressed tumour cells inhibit tumour growth by converting regulatory T cells to Th17 cells via IL-6.
Neoplasms
Exosomes released by breast cancer cells under mild hyperthermic stress possess immunogenic potential and modulate polarization in vitro in macrophages.
Neoplasms
Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein.
Neoplasms
Experimentally guided structural modeling and dynamics analysis of Hsp90-p53 interactions: allosteric regulation of the Hsp90 chaperone by a client protein.
Neoplasms
Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.
Neoplasms
Exploiting polarity and chirality to probe the Hsp90 C-terminus.
Neoplasms
Exploiting the HSP60/10 chaperonin system as a chemotherapeutic target for colorectal cancer.
Neoplasms
Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells.
Neoplasms
Exploiting vulnerabilities in cancer signalling networks to combat targeted therapy resistance.
Neoplasms
Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70).
Neoplasms
Exploring weak ligand-protein interactions by long-lived NMR states: improved contrast in fragment-based drug screening.
Neoplasms
Exposure of Wistar rats to 24-h psycho-social stress alters gene expression in the inferior colliculus.
Neoplasms
Express ELISA for detection of mortalin.
Neoplasms
Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma.
Neoplasms
Expression and clinical significance of glucose regulated proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus.
Neoplasms
Expression and localization of GRP75 in human epithelial tumors and normal tissues.
Neoplasms
Expression and purification of recombinant NRL-Hsp90? and Cdc37-CRL proteins for in vitro Hsp90/Cdc37 inhibitors screening.
Neoplasms
Expression and roles of heat shock proteins in human breast cancer.
Neoplasms
Expression and significance of glucose-regulated protein 78 in human osteosarcoma.
Neoplasms
Expression and therapeutic relevance of heat shock protein 90 in pancreatic endocrine tumors.
Neoplasms
Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma.
Neoplasms
Expression of ?B-crystallin and its potential anti-apoptotic role in oral verrucous carcinoma.
Neoplasms
Expression of a defective mouse mammary tumor virus envelope glycoprotein precursor which binds stably to GRP78 within the lumen of the endoplasmic reticulum is associated with decreased glucocorticoid-induced apoptosis in mouse lymphoma cells.
Neoplasms
Expression of a small heat shock protein 27 (HSP27) in mouse skin tumors induced by UVB-irradiation.
Neoplasms
Expression of a unique drug-resistant Hsp90 ortholog by the nematode Caenorhabditis elegans.
Neoplasms
Expression of Anti-apoptotic Protein BAG3 in Human Sebaceous Gland Carcinoma of the Eyelid.
Neoplasms
Expression of Antioxidant Molecules and Heat Shock Protein 27 in Thyroid Tumors.
Neoplasms
Expression of chemoresistance-related genes and heat shock protein 72 in hyperthermic isolated limb perfusion of malignant melanoma: an experimental study.
Neoplasms
Expression of CRYAB with the angiogenesis and poor prognosis for human gastric cancer.
Neoplasms
Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance.
Neoplasms
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions.
Neoplasms
Expression of ER stress markers (GRP78/BiP and PERK) in adenoid cystic carcinoma.
Neoplasms
Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding.
Neoplasms
Expression of focal adhesion kinase in uveal melanoma and the effects of Hsp90 inhibition by 17-AAG.
Neoplasms
Expression of gene-specific RNA in cultured cells exposed to rotating 60-Hz magnetic fields.
Neoplasms
Expression of glucose regulated protein 78 (GRP78) determines colorectal cancer response to chemotherapy.
Neoplasms
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma.
Neoplasms
Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer.
Neoplasms
Expression of Heat Shock Protein 105 in Cutaneous Squamous Cell Carcinoma: Correlation with Clinicopathological Characteristics.
Neoplasms
Expression of heat shock protein 20 inversely correlated with tumor progression in patients with ovarian cancer.
Neoplasms
Expression of heat shock protein 27 in prostate cancer cell lines according to the extent of malignancy and doxazosin treatment.
Neoplasms
Expression of heat shock protein 47 in the fibrous tissue adjacent to mouse tumour subjected to photodynamic therapy.
Neoplasms
Expression of heat shock protein 70 (HSP70) in patients with colorectal adenocarcinoma--immunohistochemistry and Western blot analysis.
Neoplasms
Expression of heat shock protein 70 in nasopharyngeal carcinomas: different expression patterns correlate with distinct clinical prognosis.
Neoplasms
Expression of heat shock protein 70 in renal cell carcinoma and its relation to tumor progression and prognosis.
Neoplasms
Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients.
Neoplasms
Expression of heat shock protein 90 at the cell surface in human neuroblastoma cells.
Neoplasms
Expression of heat shock protein 90 beta in human gastric cancer tissue and SGC7901/VCR of MDR-type gastric cancer cell line.
Neoplasms
Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo.
Neoplasms
Expression of heat shock proteins HSP70 and HSP90 in endometrial carcinomas. Correlation with clinicopathology, sex steroid receptor status, and p53 protein expression.
Neoplasms
Expression of heat shock proteins in premalignant and malignant urothelial lesions of bovine urinary bladder.
Neoplasms
Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study.
Neoplasms
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Neoplasms
Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries.
Neoplasms
Expression of HSP27, HSP72 and MRP proteins in in vitro co-culture of colon tumour cell spheroids with normal cells after incubation with rhTGF- beta1 and/or CPT-11.
Neoplasms
Expression of hsp90 and cyclin D1 in human breast cancer.
Neoplasms
Expression of Hsp90 chaperome proteins in human tumor tissue.
Neoplasms
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Neoplasms
Expression of major heat shock proteins in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy.
Neoplasms
Expression of mortalin detected in human liver cancer by tissue microarrays.
Neoplasms
Expression of mutant protein p53 and Hsp70 and Hsp90 chaperones in cockles Cerastoderma edule affected by neoplasia.
Neoplasms
Expression of novel tumor markers of pancreatic adenocarcinomas in intrahepatic cholangiocarcinomas.
Neoplasms
Expression of P53 and HSP70 in Chronic Hepatitis, Liver Cirrhosis, and Early and Advanced Hepatocellular Carcinoma Tissues and Their Diagnostic Value in Hepatocellular Carcinoma: An Immunohistochemical Study.
Neoplasms
Expression of p53, bcl-2 and heat shock protein (hsp72) in malignant and benign ovarian tumours.
Neoplasms
Expression of stress response protein glucose regulated protein-78 mediated by c-Myb.
Neoplasms
Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancer.
Neoplasms
Expression of the 27-kDa heat shock protein in human epidermis and in epidermal neoplasms: an immunohistological study.
Neoplasms
Expression of the CD117, COX-2 and HSP90 antigens and cell proliferation in fine-needle-aspirated cells from metastatic melanomas.
Neoplasms
Expression of the heat shock cognate protein HSP73 correlates with tumour thickness of primary melanomas and is enhanced in melanoma metastases.
Neoplasms
Expression of the heat shock protein HSP27 in human ovarian cancer.
Neoplasms
Expression of the molecular chaperone ?B-crystallin in infiltrating ductal breast carcinomas and the significance thereof: an immunohistochemical and proteomics-based strategy.
Neoplasms
Expression of the small heat shock protein (hsp) 27 in human astrocytomas correlates with histologic grades and tumor growth fractions.
Neoplasms
Expression of tumor antigens and heat-shock protein 70 in breast cancer cells after high-intensity focused ultrasound ablation.
Neoplasms
Expression pattern of heat shock protein 90 in patients with oral squamous cell carcinoma in northern Taiwan.
Neoplasms
Expression patterns of Trk-A, Trk-B, GRP78, and p75NRT in olfactory neuroblastoma.
Neoplasms
Expression Profile of Genes Associated with the Proteins Degradation Pathways in Colorectal adenocarcinoma.
Neoplasms
Expression profile of the telomeric complex discriminates between benign and malignant pheochromocytoma.
Neoplasms
Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets.
Neoplasms
Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer.
Neoplasms
Extracellular 70-kd heat shock protein in mid-trimester amniotic fluid and its effect on cytokine production by ex vivo-cultured amniotic fluid cells.
Neoplasms
Extracellular heat shock protein 70 inhibits tumour necrosis factor-alpha induced proinflammatory mediator production in fibroblast-like synoviocytes.
Neoplasms
Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis.
Neoplasms
Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells.
Neoplasms
Extracellular HSP70-peptide complexes promote the proliferation of hepatocellular carcinoma cells via TLR2/4/JNK1/2MAPK pathway.
Neoplasms
Extracellular HSP70/HSP70-PCs promote epithelial-mesenchymal transition of hepatocarcinoma cells.
Neoplasms
Extracellular Hsp90 (eHsp90) as the Actual Target in Clinical Trials: Intentionally or Unintentionally.
Neoplasms
Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment.
Neoplasms
Extracellular Hsp90 serves as a co-factor for MAPK activation and latent viral gene expression during de novo infection by KSHV.
Neoplasms
Extracellular Hsp90 serves as a co-factor for NF-?B activation and cellular pathogenesis induced by an oncogenic herpesvirus.
Neoplasms
Extracellular HSP90: conquering the cell surface.
Neoplasms
Extracellular Hsp90? and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.
Neoplasms
Extracellular roles for the molecular chaperone, hsp90.
Neoplasms
Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma.
Neoplasms
Extracellular Vesicle Subtypes Released From Activated or Apoptotic T-Lymphocytes Carry a Specific and Stimulus-Dependent Protein Cargo.
Neoplasms
Extreme winter cold-induced osmoregulatory, metabolic, and physiological responses in European seabass (Dicentrarchus labrax) acclimatized at different salinities.
Neoplasms
F1F0-ATP synthase functions as a co-chaperone of Hsp90-substrate protein complexes.
Neoplasms
Fabrication of Electrochemical Biosensor Based on Titanium Dioxide Nanotubes and Silver Nanoparticles for Heat Shock Protein 70 Detection.
Neoplasms
Fas ligation and tumor necrosis factor ? activation of murine astrocytes promote heat shock factor-1 activation and heat shock protein expression leading to chemokine induction and cell survival.
Neoplasms
Fatty Acid Oxidation Is an Adaptive Survival Pathway Induced in Prostate Tumors by HSP90 Inhibition.
Neoplasms
FBW7-Dependent Mcl-1 Degradation Mediates the Anticancer Effect of Hsp90 Inhibitors.
Neoplasms
Fe3 O4 nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.
Neoplasms
Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90.
Neoplasms
Feeding a Saccharomyces cerevisiae fermentation product improves udder health and immune response to a Streptococcus uberis mastitis challenge in mid-lactation dairy cows.
Neoplasms
Fever-range hyperthermia vs. hypothermia effect on cancer cell viability, proliferation and HSP90 expression.
Neoplasms
First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90.
Neoplasms
First-in-human phase I dose escalation study of a second-generation non-ansamycin HSP90 inhibitor, AT13387, in patients with advanced solid tumors.
Neoplasms
First-in-human phase I dose-escalation study of the HSP90 inhibitor AUY922 in patients with advanced solid tumors.
Neoplasms
First-in-Human Phase I Study of an Oral HSP90 Inhibitor, TAS-116, in Patients with Advanced Solid Tumors.
Neoplasms
First-in-human study of the epichaperome inhibitor PU-H71: clinical results and metabolic profile.
Neoplasms
FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.
Neoplasms
Flavones and flavonols may have clinical potential as CK2 inhibitors in cancer therapy.
Neoplasms
Flower-like gold nanoparticles for enhanced photothermal anticancer therapy by the delivery of pooled siRNA to inhibit heat shock stress response.
Neoplasms
Fluorine- and rhenium-containing geldanamycin derivatives as leads for the development of molecular probes for imaging Hsp90.
Neoplasms
Fluoropyrimidin-2,4-dihydroxy-5-isopropylbenzamides as antitumor agents against CRC and NSCLC cancer cells.
Neoplasms
Folate receptor-targeted hybrid lipid-core nanocapsules for sequential delivery of doxorubicin and tanespimycin.
Neoplasms
Forced expression of heat-shock protein 70 increases the secretion of Hsp70 and provides protection against tumour growth.
Neoplasms
Four new antitumor metabolites isolated from a mutant 3-f-31 strain derived from Penicillium purpurogenum G59.
Neoplasms
FOXP2 promotes tumor proliferation and metastasis by targeting GRP78 in triple-negative breast cancer.
Neoplasms
Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90.
Neoplasms
Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.
Neoplasms
From Bacteria to Cancer: A Benzothiazole-Based DNA Gyrase B Inhibitor Redesigned for Hsp90 C-Terminal Inhibition.
Neoplasms
From protein-protein interaction to therapy response: molecular imaging of heat shock proteins.
Neoplasms
FS-93, an Hsp90 inhibitor, induces G2/M arrest and apoptosis via the degradation of client proteins in oncogene addicted and derived resistant cancer cells.
Neoplasms
Function of HSP90 and p23 in the telomerase complex of thyroid tumors.
Neoplasms
Functional alterations in macrophages after hypoxia selection.
Neoplasms
Functional analysis of Hsp70 inhibitors.
Neoplasms
Functional and prognostic role of ZAP-70 in chronic lymphocytic leukaemia.
Neoplasms
Functional characterization of heat shock protein 90 targeted compounds.
Neoplasms
Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action.
Neoplasms
Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells.
Neoplasms
Functional proteomic analysis reveals that fungal immunomodulatory protein reduced expressions of heat shock proteins correlates to apoptosis in lung cancer cells.
Neoplasms
Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness.
Neoplasms
Functional role of Hsp60 as a positive regulator of human viral infection progression.
Neoplasms
Functional significance of minor structural and expression changes in stress chaperone mortalin.
Neoplasms
Functional Significance of Point Mutations in Stress Chaperone Mortalin and Their Relevance to Parkinson Disease.
Neoplasms
Functional state of the Hsp27 chaperone as a molecular marker of an unfavorable course of larynx cancer.
Neoplasms
Fungal mycotoxin penisuloxazin A, a novel C-terminal Hsp90 inhibitor and characteristics of its analogues on Hsp90 function related to binding sites.
Neoplasms
Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines.
Neoplasms
Fusion protein of ATPase domain of Hsc70 with TRP2 acting as a tumor vaccine against B16 melanoma.
Neoplasms
GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Neoplasms
Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2.
Neoplasms
Gambogic acid inhibits Hsp90 and deregulates TNF-?/NF-?B in HeLa cells.
Neoplasms
Gamma delta T cell recognition of tumor Ig peptide.
Neoplasms
gammadelta T cells lyse autologous and allogenic oesophageal tumours: involvement of heat-shock proteins in the tumour cell lysis.
Neoplasms
Ganetespib and HSP90: Translating Preclinical Hypotheses into Clinical Promise.
Neoplasms
Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer.
Neoplasms
Ganetespib for small cell lung cancer.
Neoplasms
Ganetespib in Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor-resistant Non-small Cell Lung Cancer.
Neoplasms
Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling.
Neoplasms
Ganetespib targets multiple levels of the receptor tyrosine kinase signaling cascade and preferentially inhibits ErbB2-overexpressing breast cancer cells.
Neoplasms
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.
Neoplasms
Ganetespib, an HSP90 inhibitor, kills Epstein-Barr virus (EBV)-infected B and T cells and reduces the percentage of EBV-infected cells in the blood.
Neoplasms
Ganetespib: research and clinical development.
Neoplasms
Gastroprotective effect of crocin in ethanol-induced gastric injury in rats.
Neoplasms
Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis.
Neoplasms
Gedunin isolated from the mangrove plant Xylocarpus granatum exerts its anti-proliferative activity in ovarian cancer cells through G2/M-phase arrest and oxidative stress-mediated intrinsic apoptosis.
Neoplasms
Geldanamycin administration reduces the amount of primordial germ cells in the mouse embryo.
Neoplasms
Geldanamycin Analog 17-DMAG Limits Apoptosis in Human Peripheral Blood Cells by Inhibition of p53 Activation and its Interaction with Heat-Shock Protein 90 kDa after Exposure to Ionizing Radiation.
Neoplasms
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.
Neoplasms
Geldanamycin and its anti-cancer activities.
Neoplasms
Geldanamycin and its derivatives as Hsp90 inhibitors.
Neoplasms
Geldanamycin anisimycins activate Rho and stimulate Rho- and ROCK-dependent actin stress fiber formation.
Neoplasms
Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity.
Neoplasms
Geldanamycin induces cell cycle arrest in K562 erythroleukemic cells.
Neoplasms
Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells.
Neoplasms
Geldanamycin, an inhibitor of Hsp90, sensitizes human tumour cells to radiation.
Neoplasms
Geldanamycin, radicicol, and chimeric inhibitors of the Hsp90 N-terminal ATP binding site.
Neoplasms
Geldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60).
Neoplasms
Geldanamycin-Induced PCNA Degradation in Isolated Hsp90 Complex from Cancer Cells.
Neoplasms
Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo.
Neoplasms
Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.
Neoplasms
Gene Copy Number and Post-Transductional Mechanisms Regulate TRAP1 Expression in Human Colorectal Carcinomas.
Neoplasms
Gene expression of heat shock protein 70, interleukin-1? and tumor necrosis factor ? as tools to identify immunotoxic effects on Xenopus laevis: a dose-response study with benzo[a]pyrene and its degradation products.
Neoplasms
Gene expression profiles of mitochondria-endoplasmic reticulum tethering in human gingival fibroblasts in response to periodontal pathogens.
Neoplasms
Generation of anti-tumor immunity using mammalian heat shock protein 70 DNA vaccines for cancer immunotherapy.
Neoplasms
Generation of cytotoxic T lymphocytes by MHC class I ligands fused to heat shock cognate protein 70.
Neoplasms
Generation of multiple Peptide cocktail-pulsed dendritic cells as a cancer vaccine.
Neoplasms
Genes and proteins governing the cellular sensitivity to HSP90 inhibitors: a mechanistic perspective.
Neoplasms
Genetic association of promoter in GRP78 gene with nasopharyngeal carcinoma in a Chinese population.
Neoplasms
Genetic polymorphisms and risk for acute renal failure in preterm neonates.
Neoplasms
Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition.
Neoplasms
Genetic susceptibility markers in Danish patients with type 1 (insulin-dependent) diabetes--evidence for polygenicity in man. Danish Study Group of Diabetes in Childhood.
Neoplasms
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions.
Neoplasms
Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma.
Neoplasms
Genistein induces apoptosis in vitro and has antitumor activity against human leukemia HL-60 cancer cell xenograft growth in vivo.
Neoplasms
Genome-wide analysis of differentially expressed genes during the early stages of tomato infection by a potyvirus.
Neoplasms
Germ cell-specific heat shock protein 70-2 is expressed in cervical carcinoma and is involved in the growth, migration, and invasion of cervical cells.
Neoplasms
Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells.
Neoplasms
Glioma: What is the role of c-Myc, hsp90 and telomerase?
Neoplasms
Global targeting of subcellular heat shock protein-90 networks for therapy of glioblastoma.
Neoplasms
Glu-108 in Saccharomyces cerevisiae Rad51 Is Critical for DNA Damage-Induced Nuclear Function.
Neoplasms
Glucose oxidase-mediated tumor starvation therapy combined with photothermal therapy for colon cancer.
Neoplasms
Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.
Neoplasms
Glucose regulated protein 78: A critical link between tumor microenvironment and cancer hallmarks.
Neoplasms
Glucose regulated proteins in cancer progression, drug resistance and immunotherapy.
Neoplasms
Glucose- regulated protein 78 (GRP78) in renal cell carcinoma: A novel biomarker for predicting tumor behavior.
Neoplasms
Glucose-deprived HT-29 human colon carcinoma cells are sensitive to verrucosidin as a GRP78 down-regulator.
Neoplasms
Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders.
Neoplasms
Glucose-regulated protein 78 (GRP78) as a potential novel biomarker and therapeutic target in multiple myeloma.
Neoplasms
Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway.
Neoplasms
Glucose-Regulated Protein 78 (GRP78) Silencing Enhances Cell Migration but Does Not Influence Cell Proliferation in Hepatocellular Carcinoma.
Neoplasms
Glucose-regulated protein 78 as a novel effector of BRCA1 for inhibiting stress-induced apoptosis.
Neoplasms
Glucose-regulated protein 78 contributes to the proliferation and tumorigenesis of human colorectal carcinoma via AKT and ERK pathways.
Neoplasms
Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness.
Neoplasms
Glucose-regulated protein 78 expression in urothelial carcinoma of the upper urinary tract.
Neoplasms
Glucose-Regulated Protein 78 Is a Novel Contributor to Acquisition of Resistance to Sorafenib in Hepatocellular Carcinoma.
Neoplasms
Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells.
Neoplasms
Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention.
Neoplasms
Glucose-regulated protein 78 silencing down-regulates vascular endothelial growth factor/vascular endothelial growth factor receptor 2 pathway to suppress human colon cancer tumor growth.
Neoplasms
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.
Neoplasms
Glucose-related protein (GRP78) and its relationship to the drug-resistance proteins P170, GST-pi, LRP56 and angiogenesis in non-small cell lung carcinomas.
Neoplasms
Glucose-Related Protein 78 Expression and Its Effects on Cisplatin-Resistance in Cervical Cancer.
Neoplasms
Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells.
Neoplasms
Glutamine Synthetase, Heat shock Protein-70, and Glypican-3 in Intrahepatic Cholangiocarcinoma and Tumors Metastatic to Liver.
Neoplasms
Gold nanoparticles loaded with cullin-5 DNA increase sensitivity to 17-AAG in cullin-5 deficient breast cancer cells.
Neoplasms
Goniothalamin enhances the ATPase activity of the molecular chaperone Hsp90 but inhibits its chaperone activity.
Neoplasms
Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation.
Neoplasms
Gr(i)p the ER to Stress Out Melanoma.
Neoplasms
Granulin-epithelin precursor interacts with 78-kDa glucose-regulated protein in hepatocellular carcinoma.
Neoplasms
Granulocyte-macrophage colony-stimulating factor gene-transduced tumor cells combined with tumor-derived gp96 inhibit tumor growth in mice.
Neoplasms
Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70-Positive Tumors for Multimodal Cancer Theranostics.
Neoplasms
Green synthesis of ultra-small VOx nanodots for acidic-activated HSP60 inhibition and therapeutic enhancement.
Neoplasms
Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
Neoplasms
Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy.
Neoplasms
GRP-78 secreted by tumor cells blocks the anti-angiogenic activity of bortezomib.
Neoplasms
GRP78 / BiP / HSPA5 / Dna K is a universal therapeutic target for human disease.
Neoplasms
GRP78 and next generation cancer hallmarks: An underexplored molecular target in cancer chemoprevention research.
Neoplasms
GRP78 as a Novel Predictor of Responsiveness to Chemotherapy in Breast Cancer.
Neoplasms
GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Neoplasms
Grp78 as a therapeutic target for refractory head-neck cancer with CD24(-)CD44(+) stemness phenotype.
Neoplasms
GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy.
Neoplasms
GRP78 at the Centre of the Stage in Cancer and Neuroprotection.
Neoplasms
GRP78 enabled micelle-based glioma targeted drug delivery.
Neoplasms
GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the ?-catenin signaling.
Neoplasms
GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastic tumors.
Neoplasms
GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma.
Neoplasms
GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice.
Neoplasms
GRP78 in lung cancer.
Neoplasms
GRP78 induction in cancer: therapeutic and prognostic implications.
Neoplasms
GRP78 Influences Chemoresistance and Prognosis in Cancer.
Neoplasms
GRP78 inhibition enhances ATF4-induced cell death by the deubiquitination and stabilization of CHOP in human osteosarcoma.
Neoplasms
GRP78 Is a Targetable Receptor on Cancer and Stromal Cells.
Neoplasms
GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKK?.
Neoplasms
GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis.
Neoplasms
GRP78 Mediates Cell Growth and Invasiveness in Endometrial Cancer.
Neoplasms
GRP78 mediates radiation resistance of a stem cell-like subpopulation within the MCF-7 breast cancer cell line.
Neoplasms
GRP78 mediates the therapeutic efficacy of curcumin on colon cancer.
Neoplasms
GRP78 modulates cell adhesion markers in prostate Cancer and multiple myeloma cell lines.
Neoplasms
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Neoplasms
GRP78 positively regulates estrogen?stimulated cell growth mediated by ER??36 in gastric cancer cells.
Neoplasms
GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Neoplasms
GRP78 Promotes Hepatocellular Carcinoma proliferation by increasing FAT10 expression through the NF-?B pathway.
Neoplasms
Grp78 promotes the invasion of hepatocellular carcinoma.
Neoplasms
GRP78 promotes the invasion of pancreatic cancer cells by FAK and JNK.
Neoplasms
GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer.
Neoplasms
GRP78 secreted by colon cancer cells facilitates cell proliferation via PI3K/Akt signaling.
Neoplasms
GRP78 secreted by tumor cells stimulates differentiation of bone marrow mesenchymal stem cells to cancer-associated fibroblasts.
Neoplasms
GRP78 signaling hub a receptor for targeted tumor therapy.
Neoplasms
GRP78 targeting: Hitting two birds with a stone.
Neoplasms
GRP78 up-regulation is associated with androgen receptor status, Hsp70-Hsp90 client proteins and castrate-resistant prostate cancer.
Neoplasms
GRP78-targeted in-silico virtual screening of novel anticancer agents.
Neoplasms
GRP78-targeted nanotherapy against castrate-resistant prostate cancer cells expressing membrane GRP78.
Neoplasms
GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy.
Neoplasms
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
Neoplasms
GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases.
Neoplasms
GRP78: A cell's response to stress.
Neoplasms
Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells.
Neoplasms
GRP94/gp96 elicits ERK activation in murine macrophages. A role for endotoxin contamination in NF-kappa B activation and nitric oxide production.
Neoplasms
Guardian of the furnace: mitochondria, TRAP1, ROS and stem cell maintenance.
Neoplasms
Guizhi-Shaoyao-Zhimu decoction attenuates rheumatoid arthritis partially by reversing inflammation-immune system imbalance.
Neoplasms
Haematoporphyrin based photodynamic therapy combined with hyperthermia provided effective therapeutic vaccine effect against colon cancer growth in mice.
Neoplasms
Hansenula polymorpha expressed heat shock protein gp96 exerts potent T cell activation activity as an adjuvant.
Neoplasms
HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma.
Neoplasms
HDAC6 deacetylates p53 at lysines 381/382 and differentially coordinates p53-induced apoptosis.
Neoplasms
HDN-1 induces cell differentiation toward apoptosis in promyelocytic leukemia cells depending on its selective effect on client proteins of Hsp90.
Neoplasms
Heat induced release of Hsp70 from prostate carcinoma cells involves both active secretion and passive release from necrotic cells.
Neoplasms
Heat shock and 5-azacytidine inhibit nitric oxide synthesis and tumor necrosis factor-alpha secretion in activated macrophages.
Neoplasms
Heat shock cognate 70 mutations in sporadic breast carcinoma.
Neoplasms
Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells.
Neoplasms
Heat shock cognate protein 70 encodes antigenic epitopes recognised by HLA-B4601-restricted cytotoxic T lymphocytes from cancer patients.
Neoplasms
Heat Shock Cognate Protein 70 Enhanced Integrin ?1 Mediated Invasion in Cancer Cells.
Neoplasms
Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux.
Neoplasms
Heat shock factor 1 confers resistance to lapatinib in ERBB2-positive breast cancer cells.
Neoplasms
Heat shock fusion protein induces both specific and nonspecific anti-tumor immunity.
Neoplasms
Heat shock protein (HSP)27: a further refinement in the diagnosis of suspicious fine needle aspirates of breast.
Neoplasms
Heat shock protein (HSP70) expression in septic patients.
Neoplasms
Heat shock protein 10 (Hsp10) in immune-related diseases: one coin, two sides.
Neoplasms
Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production.
Neoplasms
Heat shock protein 105 is overexpressed in a variety of human tumors.
Neoplasms
Heat shock protein 105 is overexpressed in squamous cell carcinoma and extramammary Paget disease but not in basal cell carcinoma.
Neoplasms
Heat shock protein 105 peptide vaccine could induce antitumor immune reactions in a phase I clinical trial.
Neoplasms
Heat shock protein 22 overexpression is associated with the progression and prognosis in gastric cancer.
Neoplasms
Heat Shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF.
Neoplasms
Heat shock protein 27 and p16 immunohistochemistry in cervical intraepithelial neoplasia and squamous cell carcinoma.
Neoplasms
Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma.
Neoplasms
Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma.
Neoplasms
Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation.
Neoplasms
Heat Shock Protein 27 Expression is Inversely Correlated with Atrophic Gastritis and Intraepithelial Neoplasia.
Neoplasms
Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells.
Neoplasms
Heat shock protein 27 is associated with irinotecan resistance in human colorectal cancer cells.
Neoplasms
Heat shock protein 27 is expressed in normal and malignant human melanocytes in vivo.
Neoplasms
Heat shock protein 27 is over-expressed in tumor tissues and increased in sera of patients with gastric adenocarcinoma.
Neoplasms
Heat Shock Protein 27 Phosphorylation Regulates Tumor Cell Migration under Shear Stress.
Neoplasms
Heat shock protein 27 phosphorylation state is associated with cancer progression.
Neoplasms
Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology.
Neoplasms
Heat shock protein 27 protects L929 cells from cisplatin-induced apoptosis by enhancing Akt activation and abating suppression of thioredoxin reductase activity.
Neoplasms
Heat shock protein 27 was up-regulated in cisplatin resistant human ovarian tumor cell line and associated with the cisplatin resistance.
Neoplasms
Heat Shock Protein 27-Targeted Heptapeptide of the PKC? Catalytic V5 Region Sensitizes Tumors with Radio- and Chemoresistance.
Neoplasms
Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells.
Neoplasms
Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1?.
Neoplasms
Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer.
Neoplasms
Heat shock protein 47 regulated by miR-29a to enhance glioma tumor growth and invasion.
Neoplasms
Heat Shock Protein 60 as a Mediator of Adipose Tissue Inflammation and Insulin Resistance.
Neoplasms
Heat shock protein 60 causes osteoclastic bone resorption via toll-like receptor-2 in estrogen deficiency.
Neoplasms
Heat Shock Protein 60 in Hepatocellular Carcinoma: Insights and Perspectives.
Neoplasms
Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery.
Neoplasms
Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer.
Neoplasms
Heat Shock Protein 60 Regulation of the Mitochondrial Permeability Transition Pore in Tumor Cells.
Neoplasms
Heat shock protein 70 (Hsp70) membrane expression on head-and-neck cancer biopsy-a target for natural killer (NK) cells.
Neoplasms
Heat Shock Protein 70 (Hsp70) Peptide Activated Natural Killer (NK) Cells for the Treatment of Patients with Non-Small Cell Lung Cancer (NSCLC) after Radiochemotherapy (RCTx) - From Preclinical Studies to a Clinical Phase II Trial.
Neoplasms
Heat shock protein 70 / MAGE-1 tumor vaccine can enhance the potency of MAGE-1-specific cellular immune responses in vivo.
Neoplasms
Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells.
Neoplasms
Heat shock protein 70 and HLA-DR molecules tissue expression. Prognostic implications in colorectal cancer.
Neoplasms
Heat shock protein 70 and nitric oxide concentrations in non-tumorous and neoplastic canine mammary tissues: preliminary results - Short communication.
Neoplasms
Heat shock protein 70 and tumor necrosis factor alpha in Taiwanese patients with dementia.
Neoplasms
Heat shock protein 70 and tumor-infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).
Neoplasms
Heat shock protein 70 antisense oligonucleotide inhibits cell growth and induces apoptosis in human gastric cancer cell line SGC-7901.
Neoplasms
Heat shock protein 70 downregulation inhibits proliferation, migration and tumorigenicity in hepatocellular carcinoma cells.
Neoplasms
Heat shock protein 70 expression and effect of combined transcatheter arterial embolization and radiofrequency ablation in the rabbit VX2 liver tumour model.
Neoplasms
Heat shock protein 70 gene polymorphisms and cancer risk: a meta-analysis.
Neoplasms
Heat shock protein 70 genotypes HSPA1B and HSPA1L influence cytokine concentrations and interfere with outcome after major injury.
Neoplasms
Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake.
Neoplasms
Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70.
Neoplasms
Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70.
Neoplasms
Heat shock protein 70 inhibits apoptosis in cancer cells through simultaneous and independent mechanisms.
Neoplasms
Heat shock protein 70 is able to prevent heat shock-induced resistance of target cells to CTL.
Neoplasms
Heat shock protein 70 is acute phase reactant: response elicited by tumor treatment with photodynamic therapy.
Neoplasms
Heat shock protein 70 is induced in mouse human colon tumor xenografts after sublethal radiofrequency ablation.
Neoplasms
Heat shock protein 70 is required for the survival of cancer cells.
Neoplasms
Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes.
Neoplasms
Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma.
Neoplasms
Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Neoplasms
Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity.
Neoplasms
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization.
Neoplasms
Heat shock protein 70 silencing enhances apoptosis inducing factor-mediated cell death in hepatocellular carcinoma HepG(2) cells.
Neoplasms
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells.
Neoplasms
Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage.
Neoplasms
Heat shock protein 70, erythropoietin, and cancer.
Neoplasms
Heat shock protein 70, released from heat-stressed tumor cells, initiates antitumor immunity by inducing tumor cell chemokine production and activating dendritic cells via TLR4 pathway.
Neoplasms
Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer.
Neoplasms
Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth.
Neoplasms
Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer.
Neoplasms
Heat shock protein 70-2 and tumor necrosis factor-? gene polymorphisms in Chinese children with Henoch-Schönlein purpura.
Neoplasms
Heat shock protein 70-associated peptides elicit specific cancer immunity.
Neoplasms
Heat shock protein 72 expression in osteosarcomas correlates with good response to neoadjuvant chemotherapy.
Neoplasms
Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells.
Neoplasms
Heat Shock Protein 90 (HSP90) and Her2 in Adenocarcinomas of the Esophagus.
Neoplasms
Heat shock protein 90 (hsp90) expression and breast cancer.
Neoplasms
Heat Shock Protein 90 (Hsp90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivo.
Neoplasms
Heat Shock Protein 90 (Hsp90)-Inhibitor-Luminespib-Loaded-Protein-Based Nanoformulation for Cancer Therapy.
Neoplasms
Heat Shock Protein 90 Alpha, Lass B Member 1: a Key Regulative Gene of Monitoring Duodenal Tumor for Obesity Induced by High-Fat Diet.
Neoplasms
Heat shock protein 90 and role of its chemical inhibitors in treatment of hematologic malignancies.
Neoplasms
Heat shock protein 90 as a molecular target for cancer therapeutics.
Neoplasms
Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma.
Neoplasms
Heat Shock Protein 90 Family Isoforms as Prognostic Biomarkers and Their Correlations with Immune Infiltration in Breast Cancer.
Neoplasms
Heat shock protein 90 in neurodegenerative diseases.
Neoplasms
Heat shock protein 90 in plants: molecular mechanisms and roles in stress responses.
Neoplasms
Heat shock protein 90 inhibition abrogates hepatocellular cancer growth through cdc2-mediated G(2)/M cell cycle arrest and apoptosis.
Neoplasms
Heat shock protein 90 inhibition by 17-Dimethylaminoethylamino-17-demethoxygeldanamycin protects blood-brain barrier integrity in cerebral ischemic stroke.
Neoplasms
Heat Shock Protein 90 Inhibition Depletes LATS1 and LATS2, Two Regulators of the Mammalian Hippo Tumor Suppressor Pathway.
Neoplasms
Heat Shock Protein 90 Inhibition in Cancer Drug Discovery: From Chemistry to Futural Clinical Applications.
Neoplasms
Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor.
Neoplasms
Heat shock protein 90 inhibition in the inflamed lungs.
Neoplasms
Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
Neoplasms
Heat shock protein 90 inhibition results in altered downstream signaling of mutant KIT and exerts synergistic effects on Kasumi-1 cells when combining with histone deacetylase inhibitor.
Neoplasms
Heat shock protein 90 inhibition: A potential double- or triple-edged sword in the treatment of mucous membrane pemphigoid.
Neoplasms
Heat shock protein 90 inhibition: rationale and clinical potential.
Neoplasms
Heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin potentiates the radiation response of tumor cells grown as monolayer cultures and spheroids by inducing apoptosis.
Neoplasms
Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells.
Neoplasms
Heat shock protein 90 inhibitor BIIB021 (CNF2024) depletes NF-kappaB and sensitizes Hodgkin's lymphoma cells for natural killer cell-mediated cytotoxicity.
Neoplasms
Heat Shock Protein 90 Inhibitor Effects on Pancreatic Cancer Cell Cultures.
Neoplasms
Heat shock protein 90 inhibitor is synergistic with JAK2 inhibitor and overcomes resistance to JAK2-TKI in human myeloproliferative neoplasm cells.
Neoplasms
Heat shock protein 90 inhibitor mycoepoxydiene modulates kinase signaling in cervical cancer cells and inhibits in-vivo tumor growth.
Neoplasms
Heat shock protein 90 inhibitor regulates necroptotic cell death via down-regulation of receptor interacting proteins.
Neoplasms
Heat Shock Protein 90 Inhibitors as Therapeutic Agents.
Neoplasms
Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells.
Neoplasms
Heat shock protein 90 inhibitors block the antinociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models.
Neoplasms
Heat shock protein 90 inhibitors in non-small-cell lung cancer.
Neoplasms
Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions.
Neoplasms
Heat shock protein 90 inhibitors induce functional inhibition of human natural killer cells in a dose-dependent manner.
Neoplasms
Heat shock protein 90 inhibitors repress latent membrane protein 1 (LMP1) expression and proliferation of Epstein-Barr virus-positive natural killer cell lymphoma.
Neoplasms
Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation.
Neoplasms
Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions.
Neoplasms
Heat Shock Protein 90 Inhibitors: New Mode of Therapy to Overcome Endocrine Resistance.
Neoplasms
Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.
Neoplasms
Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors.
Neoplasms
Heat shock protein 90 is a putative therapeutic target in patients with recurrent advanced-stage ovarian carcinoma with serous effusions.
Neoplasms
Heat shock protein 90 is a rational molecular target in breast cancer.
Neoplasms
Heat Shock Protein 90 is Associated with Hyperplasia and Neoplastic Transformation of Canine Prostatic Epithelial Cells.
Neoplasms
Heat shock protein 90 is critical for regulation of phenotype and functional activity of human T lymphocytes and NK cells.
Neoplasms
Heat shock protein 90 is involved in the regulation of HMGA2-driven growth and epithelial-to-mesenchymal transition of colorectal cancer cells.
Neoplasms
Heat shock protein 90 mediates the apoptosis and autophage in nicotinic-mycoepoxydiene-treated HeLa cells.
Neoplasms
Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.
Neoplasms
Heat shock protein 90 promotes RNA helicase DDX5 accumulation and exacerbates hepatocellular carcinoma by inhibiting autophagy.
Neoplasms
Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex.
Neoplasms
Heat Shock Protein 90 Regulates Subcellular Localization of Smads in Mv1Lu Cells.
Neoplasms
Heat shock protein 90 regulates the metaphase-anaphase transition in a polo-like kinase-dependent manner.
Neoplasms
Heat shock protein 90 suppresses tumor necrosis factor alpha induced apoptosis by preventing the cleavage of Bid in NIH3T3 fibroblasts.
Neoplasms
Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells.
Neoplasms
Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3?/?-Catenin Signaling.
Neoplasms
Heat shock protein 90-? over-expression is associated with poor survival in stage I lung adenocarcinoma patients.
Neoplasms
Heat shock protein 90-mediated peptide-selective presentation of cytosolic tumor antigen for direct recognition of tumors by CD4(+) T cells.
Neoplasms
Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors.
Neoplasms
Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors.
Neoplasms
Heat shock protein 90.
Neoplasms
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Neoplasms
Heat shock protein 90: a unique chemotherapeutic target.
Neoplasms
Heat shock protein 90: its inhibition and function.
Neoplasms
Heat shock protein 90: the cancer chaperone.
Neoplasms
Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?
Neoplasms
Heat shock protein 90? in thymic epithelial tumors and non-thymomatous myasthenia gravis.
Neoplasms
Heat Shock Protein 90? Provides an Effective and Novel Diagnosis Strategy for Nasopharyngeal Carcinoma.
Neoplasms
Heat shock protein 90alpha recruits FLIPS to the death-inducing signaling complex and contributes to TRAIL resistance in human glioma.
Neoplasms
Heat shock protein 90B1 plays an oncogenic role and is a target of microRNA-223 in human osteosarcoma.
Neoplasms
Heat shock protein and p53 expression in head and neck squamous cell carcinoma.
Neoplasms
Heat shock protein as molecular targets for breast cancer therapeutics.
Neoplasms
Heat Shock Protein Association with Clinico-Pathological Characteristics of Gastric Cancer in Jordan : HSP70 is Predictive of Poor Prognosis.
Neoplasms
Heat shock protein B6 potently increases non-small cell lung cancer growth.
Neoplasms
Heat shock protein B8 promotes proliferation and migration in lung adenocarcinoma A549 cells by maintaining mitochondrial function.
Neoplasms
Heat shock protein B8, a cyclin-dependent kinase-independent cyclin D1 target gene, contributes to its effects on radiation sensitivity.
Neoplasms
Heat shock protein derived from a non-autologous tumour can be used as an anti-tumour vaccine.
Neoplasms
Heat shock protein expression analysis in canine osteosarcoma reveals HSP60 as a potentially relevant therapeutic target.
Neoplasms
Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy.
Neoplasms
Heat shock protein expression and injury optimization for laser therapy design.
Neoplasms
Heat shock protein expression and temperature distribution in prostate tumours treated with laser irradiation and nanoshells.
Neoplasms
Heat shock protein expression in canine malignant mammary tumours.
Neoplasms
Heat shock protein expression in canine osteosarcoma.
Neoplasms
Heat shock protein expression in human gliomas.
Neoplasms
Heat shock protein expression in human tumours grown in severe combined immunodeficient mice.
Neoplasms
Heat shock protein expression in oral epithelial dysplasia and squamous cell carcinoma.
Neoplasms
Heat shock protein expression in the eye and in uveal melanoma.
Neoplasms
Heat shock protein expression independently predicts clinical outcome in prostate cancer.
Neoplasms
Heat shock protein gp96 and cancer immunotherapy.
Neoplasms
Heat shock protein gp96 decreases p53 stability by regulating Mdm2 E3 ligase activity in liver cancer.
Neoplasms
Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications.
Neoplasms
Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.
Neoplasms
Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis.
Neoplasms
Heat Shock Protein Inhibitor 17-Allyamino-17-Demethoxygeldanamycin, a Potent Inductor of Apoptosis in Human Glioma Tumor Cell Lines, Is a Weak Substrate for ABCB1 and ABCG2 Transporters.
Neoplasms
Heat shock protein inhibitor, quercetin, as a novel adjuvant agent to improve radiofrequency ablation-induced tumor destruction and its molecular mechanism.
Neoplasms
Heat shock protein inhibitors and vaccines as new agents in cancer treatment.
Neoplasms
Heat shock protein inhibitors increase the efficacy of measles virotherapy.
Neoplasms
Heat shock protein reactivity of lymphocytes isolated from heterotopic rat cardiac allografts.
Neoplasms
Heat shock protein response in a prostate tumor model to interstitial thermotherapy: implications for clinical treatment.
Neoplasms
Heat shock protein vaccination and directed IL-2 therapy amplify tumor immunity rapidly following bone marrow transplantation in mice.
Neoplasms
Heat shock protein vaccines against cancer.
Neoplasms
Heat shock protein-60 expression was significantly correlated with the prognosis of lung adenocarcinoma.
Neoplasms
Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro.
Neoplasms
Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer.
Neoplasms
Heat shock protein-90 inhibitors enhance antigen expression on melanomas and increase T cell recognition of tumor cells.
Neoplasms
Heat shock protein-90 inhibitors: a chronicle from geldanamycin to today's agents.
Neoplasms
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation.
Neoplasms
Heat shock protein-guided dual-mode CT/MR imaging of orthotopic hepatocellular carcinoma tumor.
Neoplasms
Heat Shock Protein-Peptide and HSP-Based Immunotherapies for the Treatment of Cancer.
Neoplasms
Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity.
Neoplasms
Heat shock protein90 in lobular neoplasia of the breast.
Neoplasms
Heat Shock Proteins (HSPs) based anti-cancer vaccines.
Neoplasms
Heat shock proteins and cancer: How can nanomedicine be harnessed?
Neoplasms
Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?
Neoplasms
Heat shock proteins and cell proliferation in human breast cancer biopsy samples.
Neoplasms
Heat Shock Proteins Are Essential Components in Transformation and Tumor Progression: Cancer Cell Intrinsic Pathways and Beyond.
Neoplasms
Heat shock proteins as emerging therapeutic targets.
Neoplasms
Heat shock proteins as novel therapeutic targets in cancer.
Neoplasms
Heat shock proteins as prognostic markers of cancer.
Neoplasms
Heat shock proteins as regulators of the immune response.
Neoplasms
Heat shock proteins as targets in oncology.
Neoplasms
Heat shock proteins HSP27, HSP60, HSP70, and HSP90: expression in bladder carcinoma.
Neoplasms
Heat shock proteins in breast cancer progression--a suitable case for treatment?
Neoplasms
Heat shock proteins in cancer: chaperones of tumorigenesis.
Neoplasms
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications.
Neoplasms
Heat shock proteins in cancer: targeting the 'chaperones'.
Neoplasms
Heat shock proteins in glioblastomas.
Neoplasms
Heat shock proteins in multiple myeloma.
Neoplasms
Heat shock proteins with an emphasis on HSP 60.
Neoplasms
Heat shock proteins, autoimmunity, and cancer treatment.
Neoplasms
Heat Shock Proteins: A Potential Anticancer Target.
Neoplasms
Heat shock proteins: a therapeutic target worth to consider.
Neoplasms
Heat shock proteins: their role in urological tumors.
Neoplasms
Heat Stress and Feed Restriction Distinctly Affect Performance, Carcass and Meat Yield, Intestinal Integrity, and Inflammatory (Chemo)Cytokines in Broiler Chickens.
Neoplasms
Heat-activated nanomedicine formulation improves the anticancer potential of the HSP90 inhibitor luminespib in vitro.
Neoplasms
Heat-shock protein 70 as a tumor antigen for in vitro dendritic cell pulsing in renal cell carcinoma cases.
Neoplasms
Heat-shock protein 70 binds to a novel sequence in 5' UTR of tumor suppressor SMAR1 and regulates its mRNA stability upon Prostaglandin A2 treatment.
Neoplasms
Heat-shock protein 70-2 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumour progression and promotes migration and invasion.
Neoplasms
Heat-shock protein 70: expression in monocytes of patients with sleep apnoea and association with oxidative stress and tumour necrosis factor-alpha.
Neoplasms
Heat-shock protein 90 (Hsp90) as a molecular target for therapy of gastrointestinal cancer.
Neoplasms
Heat-shock protein 90 (Hsp90) as anticancer target for drug discovery: an ample computational perspective.
Neoplasms
Heat-shock protein 90 inhibitors as antitumor agents: a survey of the literature from 2005 to 2010.
Neoplasms
Heat-shock protein 90 inhibitors as novel cancer chemotherapeutic agents.
Neoplasms
Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update.
Neoplasms
Heat-shock protein 90 inhibitors in antineoplastic therapy: is it all wrapped up?
Neoplasms
Heat-shock protein 90 inhibitors in cancer therapy: 17AAG and beyond.
Neoplasms
Heat-shock protein 90: potential involvement in the pathogenesis of malignancy and pharmacological intervention.
Neoplasms
HECTD3 Mediates an HSP90-Dependent Degradation Pathway for Protein Kinase Clients.
Neoplasms
Helicobacter pylori heat shock protein 60 antibodies are associated with gastric cancer.
Neoplasms
Helicobacter pylori-downregulated tumor necrosis factor receptor-associated protein 1 mediates apoptosis of human gastric epithelial cells.
Neoplasms
Hepatic Microwave Ablation-Induced Tumor Destruction and Animal End Point Survival Can Be Improved by Suppression of Heat Shock Protein 90.
Neoplasms
Hepatic Thermal Ablation: Effect of Device and Heating Parameters on Local Tissue Reactions and Distant Tumor Growth.
Neoplasms
Hepatitis B virus protein up-regulated HLJ1 expression via the transcription factor YY1 in human hepatocarcinoma cells.
Neoplasms
Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2.
Neoplasms
Hepatocellular tumors: immunohistochemical analyses for classification and prognostication.
Neoplasms
HER2-positive advanced breast cancer: optimizing patient outcomes and opportunities for drug development.
Neoplasms
HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer.
Neoplasms
Herbimycins D-F, Ansamycin Analogues from Streptomyces sp. RM-7-15.
Neoplasms
Heterocyclic drug-polymer conjugates for cancer targeted drug delivery.
Neoplasms
HIF-1alpha and STAT3 client proteins interacting with the cancer chaperone Hsp90: Therapeutic Considerations.
Neoplasms
HIF1?-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia.
Neoplasms
High anti tumor activity against rhabdomyosarcoma cells and low normal cells cytotoxicity of heat shock protein 90 inhibitors, with special emphasis on 17-[2-(pyrrolidin-1-yl)ethyl]-aminno-17-demethoxygeldanamycin.
Neoplasms
High concentrations of environmental ammonia induced changes in large-scale loach (Paramisgurnus dabryanus) immunity.
Neoplasms
High expression of glucose-regulated protein 78 (GRP78) is associated with metastasis and poor prognosis in patients with esophageal squamous cell carcinoma.
Neoplasms
High expression of GRP78/BiP as a novel predictor of favorable outcomes in patients with advanced thymic carcinoma.
Neoplasms
High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy.
Neoplasms
High expression of heat shock protein 90 is associated with tumor aggressiveness and poor prognosis in patients with advanced gastric cancer.
Neoplasms
High expression of heat shock proteins and heat shock factor-1 distinguishes an aggressive subset of clear cell renal cell carcinoma.
Neoplasms
High expression of HSP90 is associated with poor prognosis in patients with colorectal cancer.
Neoplasms
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
Neoplasms
High HSP90 expression is associated with decreased survival in breast cancer.
Neoplasms
High HSPA8 expression predicts adverse outcomes of acute myeloid leukemia.
Neoplasms
High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction.
Neoplasms
High Level Soluble Expression and ATPase Characterization of Human Heat Shock Protein GRP78.
Neoplasms
High levels of heat shock protein 70 are associated with pro-inflammatory cytokines and may differentiate early- from late-onset preeclampsia.
Neoplasms
High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways.
Neoplasms
High Levels of Hsp90 Cochaperone p23 Promote Tumor Progression and Poor Prognosis in Breast Cancer by Increasing Lymph Node Metastases and Drug Resistance.
Neoplasms
High-Content, High-Throughput Analysis of Cell Cycle Perturbations Induced by the HSP90 Inhibitor XL888.
Neoplasms
High-throughput screen of natural product libraries for hsp90 inhibitors.
Neoplasms
High-throughput screening assay for inhibitors of heat-shock protein 90 ATPase activity.
Neoplasms
High-throughput screening fluorescence polarization assay for tumor-specific hsp90.
Neoplasms
High-throughput screening identifies small molecule inhibitors of molecular chaperones.
Neoplasms
High-yield expression and purification of the Hsp90-associated p23, FKBP52, HOP and SGT? proteins.
Neoplasms
Higher induction of heat shock protein 72 by heat stress in cisplatin-resistant than in cisplatin-sensitive cancer cells.
Neoplasms
Highlights in experimental therapeutics.
Neoplasms
Hippocampal and Cerebellar Changes in Acute Restraint Stress and the Impact of Pretreatment with Ceftriaxone.
Neoplasms
Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease.
Neoplasms
Histologic grade and CD44 are independent predictors of axillary lymph node invasion in early (T1) breast cancer.
Neoplasms
Histological and immunohistochemical effects of L-arginine and silymarin on TNBS-induced inflammatory bowel disease in rats.
Neoplasms
Histological effect and protein expression in subthreshold transpupillary thermotherapy in rabbit eyes.
Neoplasms
Histone deacetylase 6 in cancer.
Neoplasms
Histone deacetylase activity mediates acquired resistance towards structurally diverse HSP90 inhibitors.
Neoplasms
Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein.
Neoplasms
Histone deacetylase inhibitors modulating non-epigenetic players: The novel molecular targets for therapeutic intervention.
Neoplasms
Histone deacetylation : an attractive target for cancer therapy?
Neoplasms
HLA class I binding of synthetic nonamer peptides carrying major anchor residue motifs of HLA-B27 (B*2705)-binding peptides.
Neoplasms
HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma.
Neoplasms
Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1.
Neoplasms
Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors.
Neoplasms
How autophagy controls the intestinal epithelial barrier.
Neoplasms
How Selective are Hsp90 Inhibitors for Cancer Cells over Normal Cells?
Neoplasms
HPMA Copolymer-Aminohexylgeldanamycin Conjugates Targeting Cell Surface Expressed GRP78 in Prostate Cancer.
Neoplasms
Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions.
Neoplasms
HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity.
Neoplasms
HSP 70 synthesis in clinical hyperthermia patients: preliminary results of a new technique.
Neoplasms
Hsp-27 has no diagnostic or prognostic significance in prostate or bladder cancers.
Neoplasms
HSP-27 protein expression in uveal melanoma: correlation with predicted survival.
Neoplasms
HSP105 expression in oral squamous cell carcinoma: Correlation with clinicopathological features and outcomes.
Neoplasms
Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I.
Neoplasms
Hsp110 over-expression increases the immunogenicity of the murine CT26 colon tumor.
Neoplasms
HSP20 Exerts a Protective Effect on Preeclampsia by Regulating Function of Trophoblast Cells Via Akt Pathways.
Neoplasms
Hsp27 Acts as a Master Molecular Chaperone and Plays an Essential Role in Hepatocellular Carcinoma Progression.
Neoplasms
Hsp27 and Hsp60 in human submandibular salivary gland: Quantitative patterns in healthy and cancerous tissues with potential implications for differential diagnosis and carcinogenesis.
Neoplasms
Hsp27 expression in neuroblastoma: correlation with disease stage.
Neoplasms
HSP27 expression levels are associated with the sensitivity of hepatocellular carcinoma cells to 17-allylamino-17-demethoxygeldanamycin.
Neoplasms
Hsp27 inhibition with OGX-427 sensitizes non-small cell lung cancer cells to erlotinib and chemotherapy.
Neoplasms
HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis.
Neoplasms
HSP27 knockdown produces synergistic induction of apoptosis by HSP90 and kinase inhibitors in glioblastoma multiforme.
Neoplasms
Hsp27 modulates p53 signaling and suppresses cellular senescence.
Neoplasms
Hsp27 regulates EGF/?-catenin mediated epithelial to mesenchymal transition in prostate cancer.
Neoplasms
Hsp27 silencing coordinately inhibits proliferation and promotes Fas-induced apoptosis by regulating the PEA-15 molecular switch.
Neoplasms
HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy (Review).
Neoplasms
Hsp27-induced MMP-9 expression is influenced by the Src tyrosine protein kinase yes.
Neoplasms
Hsp27: A novel therapeutic target for pediatric M4/M5 acute myeloid leukemia.
Neoplasms
HSP32 and HSP90 Immunoexpression, in Relation to Kit Pattern, Grading, and Mitotic Count in Canine Cutaneous Mast Cell Tumors.
Neoplasms
HSP40 Interacts with Pyruvate Kinase M2 and Regulates Glycolysis and Cell Proliferation in Tumor Cells.
Neoplasms
Hsp40, a possible indicator for thermotolerance of murine tumour in vivo.
Neoplasms
HSP47 as a possible marker for malignancy of tumors in vivo.
Neoplasms
HSP47 contributes to angiogenesis by induction of CCL2 in bladder cancer.
Neoplasms
HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1?.
Neoplasms
Hsp60 and Hsp10 as Antitumor Molecular Agents.
Neoplasms
Hsp60 and Hsp10 down-regulation predicts bronchial epithelial carcinogenesis in smokers with chronic obstructive pulmonary disease.
Neoplasms
Hsp60 and human aging: Les liaisons dangereuses.
Neoplasms
Hsp60 and IL-8 axis promotes apoptosis resistance in cancer.
Neoplasms
HSP60 as a drug target.
Neoplasms
Hsp60 chaperonin acts as barrier to pharmacologically induced oxidative stress mediated apoptosis in tumor cells with differential stress response.
Neoplasms
Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma.
Neoplasms
Hsp60 expression, new locations, functions and perspectives for cancer diagnosis and therapy.
Neoplasms
HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment.
Neoplasms
Hsp60 in inflamed muscle tissue is the target of regulatory autoreactive T cells in patients with juvenile dermatomyositis.
Neoplasms
Hsp60 is actively secreted by human tumor cells.
Neoplasms
HSP60 is transported through the secretory pathway of 3-MCA-induced fibrosarcoma tumour cells and undergoes N-glycosylation.
Neoplasms
HSP60 overexpression increases the protein levels of the p110? subunit of phosphoinositide 3-kinase and c-Myc.
Neoplasms
Hsp60 Post-translational Modifications: Functional and Pathological Consequences.
Neoplasms
Hsp60 regulation of tumor cell apoptosis.
Neoplasms
HSP60 silencing promotes Warburg-like phenotypes and switches the mitochondrial function from ATP production to biosynthesis in ccRCC cells.
Neoplasms
HSP60 Takes a Hit: Inhibition of Mitochondrial Protein Folding.
Neoplasms
HSP60, a protein downregulated by IGFBP7 in colorectal carcinoma.
Neoplasms
HSP60-knockdown suppresses proliferation in colorectal cancer cells via activating the adenine/AMPK/mTOR signaling pathway.
Neoplasms
Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12.
Neoplasms
HSP60-regulated Mitochondrial Proteostasis and Protein Translation Promote Tumor Growth of Ovarian Cancer.
Neoplasms
Hsp60: molecular anatomy and role in colorectal cancer diagnosis and treatment.
Neoplasms
Hsp70 (HSP70A1A) downregulation enhances the metastatic ability of cancer cells.
Neoplasms
HSP70 and ER expression in cervical intraepithelial neoplasia and cervical cancer.
Neoplasms
Hsp70 and Hsp90 of E. coli Directly Interact for Collaboration in Protein Remodeling.
Neoplasms
Hsp70 and Hsp90--a relay team for protein folding.
Neoplasms
Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.
Neoplasms
Hsp70 in cancer: back to the future.
Neoplasms
Hsp70 in Liquid Biopsies-A Tumor-Specific Biomarker for Detection and Response Monitoring in Cancer.
Neoplasms
HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes.
Neoplasms
HSP70 regulates Eg5 distribution within the mitotic spindle and modulates the cytotoxicity of Eg5 inhibitors.
Neoplasms
Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90.
Neoplasms
HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma.
Neoplasms
Hsp70, an immunological actor playing with the intracellular self under oxidative stress.
Neoplasms
Hsp70--a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck.
Neoplasms
Hsp70-2 is required for tumor cell growth and survival.
Neoplasms
HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia.
Neoplasms
HSP72 and gp96 in gastroenterological cancers.
Neoplasms
Hsp72-mediated augmentation of MHC class I surface expression and endogenous antigen presentation.
Neoplasms
Hsp90 activation and cell cycle regulation.
Neoplasms
Hsp90 Activity Modulation by Plant Secondary Metabolites.
Neoplasms
Hsp90 and angiogenesis in bone disorders--lessons from the avian growth plate.
Neoplasms
Hsp90 and Cdc37 -- a chaperone cancer conspiracy.
Neoplasms
Hsp90 and client protein maturation.
Neoplasms
HSP90 and Co-chaperones: Impact on Tumor Progression and Prospects for Molecular-Targeted Cancer Therapy.
Neoplasms
Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer.
Neoplasms
HSP90 and HSP70 are essential for stabilization and activation of the WASF3 metastasis promoting protein.
Neoplasms
HSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative Neoplasms.
Neoplasms
HSP90 and Immune Modulation in Cancer.
Neoplasms
HSP90 and the chaperoning of cancer.
Neoplasms
Hsp90 and the Fanconi anemia pathway: a molecular link between protein quality control and the DNA damage response.
Neoplasms
Hsp90 as a "Chaperone" of the Epigenome: Insights and Opportunities for Cancer Therapy.
Neoplasms
Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls.
Neoplasms
HSP90 as a marker of progression in melanoma.
Neoplasms
HSP90 as a new therapeutic target for cancer therapy: the story unfolds.
Neoplasms
HSP90 as a platform for the assembly of more effective cancer chemotherapy.
Neoplasms
Hsp90 as a therapeutic target in patients with oesophageal carcinoma.
Neoplasms
Hsp90 as an anti-cancer target.
Neoplasms
Hsp90 C-Terminal Inhibitors Exhibit Antimigratory Activity by Disrupting the Hsp90?/Aha1 Complex in PC3-MM2 Cells.
Neoplasms
Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells.
Neoplasms
Hsp90 chaperones wild-type p53 tumor suppressor protein.
Neoplasms
Hsp90 cleavage by an oxidative stress leads to its client proteins degradation and cancer cell death.
Neoplasms
HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.
Neoplasms
HSP90 expression and its association with wighteone metabolite response in HER2-positive breast cancer cells.
Neoplasms
HSP90 expression: a new predictive factor for BCG response in stage Ta-T1 grade 3 bladder tumours.
Neoplasms
Hsp90 facilitates acquired drug resistance of tumor cells through cholesterol modulation however independent of tumor progression.
Neoplasms
Hsp90 globally targets paused RNA polymerase to regulate gene expression in response to environmental stimuli.
Neoplasms
Hsp90 in Cancer: Transcriptional Roles in the Nucleus.
Neoplasms
Hsp90 in the continuum of breast ductal carcinogenesis: Evaluation in precursors, preinvasive and ductal carcinoma lesions.
Neoplasms
Hsp90 inhibition accelerates cell lysis. Anti-Hsp90 ribozyme reveals a complex mechanism of Hsp90 inhibitors involving both superoxide- and Hsp90-dependent events.
Neoplasms
HSP90 Inhibition and Cellular Stress Elicits Phenotypic Plasticity in Hematopoietic Differentiation.
Neoplasms
Hsp90 inhibition by NVP-AUY922 and NVP-BEP800 decreases migration and invasion of irradiated normoxic and hypoxic tumor cell lines.
Neoplasms
Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2.
Neoplasms
Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress.
Neoplasms
Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics.
Neoplasms
Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms.
Neoplasms
HSP90 inhibition downregulates DNA replication and repair genes via E2F1 repression.
Neoplasms
HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins.
Neoplasms
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.
Neoplasms
Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane.
Neoplasms
Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma.
Neoplasms
HSP90 inhibition induces cytotoxicity via down-regulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells.
Neoplasms
Hsp90 inhibition protects against inherited retinal degeneration.
Neoplasms
Hsp90 Inhibition Reduces TLR5 Surface Expression and NF-?B Activation in Human Myeloid Leukemia THP-1 Cells.
Neoplasms
HSP90 inhibition results in apoptosis of Philadelphia acute lymphoblastic leukaemia cells: an attractive prospect of new targeted agents.
Neoplasms
Hsp90 Inhibition Results in Glucocorticoid Receptor Degradation in Association with Increased Sensitivity to Paclitaxel in Triple-Negative Breast Cancer.
Neoplasms
HSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivo.
Neoplasms
HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells.
Neoplasms
Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation.
Neoplasms
Hsp90 inhibition: elimination of shock and stress.
Neoplasms
HSP90 inhibition: two-pronged exploitation of cancer dependencies.
Neoplasms
Hsp90 inhibitor 17-AAG inhibits progression of LuCaP35 xenograft prostate tumors to castration resistance.
Neoplasms
HSP90 inhibitor 17-AAG prevents apoptosis of cardiomyocytes via miR-93-dependent mitigation of endoplasmic reticulum stress.
Neoplasms
Hsp90 inhibitor 17-AAG sensitizes Bcl-2 inhibitor (-)-gossypol by suppressing ERK-mediated protective autophagy and Mcl-1 accumulation in hepatocellular carcinoma cells.
Neoplasms
HSP90 inhibitor 17-DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidant-antioxidant balance.
Neoplasms
Hsp90 inhibitor 17?AAG inhibits stem cell?like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway.
Neoplasms
HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates.
Neoplasms
Hsp90 inhibitor as a sensitizer of cancer cells to different therapies (review).
Neoplasms
HSP90 inhibitor AUY922 can reverse Fulvestrant induced feedback reaction in human breast cancer cells.
Neoplasms
HSP90 inhibitor CH5164840 induces micronuclei in TK6 cells via an aneugenic mechanism.
Neoplasms
HSP90 inhibitor DPB induces autophagy and more effectively apoptosis in A549 cells combined with autophagy inhibitors.
Neoplasms
HSP90 Inhibitor Encapsulated Photo-Theranostic Nanoparticles for Synergistic Combination Cancer Therapy.
Neoplasms
HSP90 Inhibitor Ganetespib (STA-9090) Inhibits Tumor Growth in c-Myc-Dependent Esophageal Squamous Cell Carcinoma.
Neoplasms
Hsp90 Inhibitor Ganetespib Sensitizes Non-Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation.
Neoplasms
Hsp90 inhibitor gedunin causes apoptosis in A549 lung cancer cells by disrupting Hsp90:Beclin-1:Bcl-2 interaction and downregulating autophagy.
Neoplasms
Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents.
Neoplasms
Hsp90 inhibitor geldanamycin enhances the antitumor efficacy of enediyne lidamycin in association with reduced DNA damage repair.
Neoplasms
Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells.
Neoplasms
Hsp90 inhibitor is a good candidate for effective combination therapy with carbon ions.
Neoplasms
Hsp90 inhibitor NMS-E973 exerts the anticancer effect against glioblastoma via induction of PUMA-mediated apoptosis.
Neoplasms
Hsp90 inhibitor NVP-AUY922 enhances radiation sensitivity of tumor cell lines under hypoxia.
Neoplasms
Hsp90 inhibitor NVP-AUY922 enhances the radiation sensitivity of lung cancer cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors.
Neoplasms
HSP90 inhibitor NVP-AUY922 induces cell apoptosis by disruption of the survivin in papillary thyroid carcinoma cells.
Neoplasms
HSP90 inhibitor PU-H71 increases radiosensitivity of breast cancer cells metastasized to visceral organs and alters the levels of inflammatory mediators.
Neoplasms
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models.
Neoplasms
HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.
Neoplasms
Hsp90 Inhibitor STA9090 Sensitizes Hepatocellular Carcinoma to Hyperthermia-Induced DNA Damage by Suppressing DNA-PKcs Protein Stability and mRNA Transcription.
Neoplasms
Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells.
Neoplasms
Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.
Neoplasms
HSP90 Inhibitor-SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors.
Neoplasms
Hsp90 inhibitors and drug resistance in cancer: The potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs.
Neoplasms
Hsp90 inhibitors and the reduction of anti-cancer drug resistance by non-genetic and genetic mechanisms.
Neoplasms
Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins.
Neoplasms
Hsp90 inhibitors as anti-cancer agents, from basic discoveries to clinical development.
Neoplasms
Hsp90 inhibitors as novel cancer chemotherapeutic agents.
Neoplasms
Hsp90 inhibitors as promising agents for radiotherapy.
Neoplasms
Hsp90 inhibitors as selective anticancer drugs.
Neoplasms
HSP90 inhibitors as therapy for multiple myeloma.
Neoplasms
Hsp90 inhibitors attenuate effect of dexamethasone on activated NF-kappaB and AP-1.
Neoplasms
Hsp90 inhibitors cause G2/M arrest associated with the reduction of Cdc25C and Cdc2 in lung cancer cell lines.
Neoplasms
Hsp90 inhibitors deplete key anti-apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin.
Neoplasms
Hsp90 inhibitors disrupt mitochondrial homeostasis in cancer cells.
Neoplasms
HSP90 inhibitors enhance differentiation and MITF (microphthalmia transcription factor) activity in osteoclast progenitors.
Neoplasms
HSP90 Inhibitors for Cancer Therapy and Overcoming Drug Resistance.
Neoplasms
Hsp90 Inhibitors in Parasitic Nematodes: Prospects and Challenges.
Neoplasms
HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells.
Neoplasms
Hsp90 Inhibitors NVP-AUY922 and NVP-BEP800 May Exert a Significant Radiosensitization on Tumor Cells along with a Cell Type-Specific Cytotoxicity.
Neoplasms
Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.
Neoplasms
Hsp90 inhibitors suppress P53 phosphorylation in LPS - induced endothelial inflammation.
Neoplasms
Hsp90 inhibitors, GA and 17AAG, lead to ER stress-induced apoptosis in rat histiocytoma.
Neoplasms
Hsp90 inhibitors: clinical development and future opportunities in oncology therapy.
Neoplasms
HSP90 Inhibitors: Current Development and Potential in Cancer Therapy.
Neoplasms
HSP90 inhibitors: multi-targeted antitumor effects and novel combinatorial therapeutic approaches in cancer therapy.
Neoplasms
Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation.
Neoplasms
HSP90 inhibits apoptosis and promotes growth by regulating HIF-1? abundance in hepatocellular carcinoma.
Neoplasms
Hsp90 interacts with AMPK and mediates acetyl-CoA carboxylase phosphorylation.
Neoplasms
HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma.
Neoplasms
Hsp90 Is a Novel Target Molecule of CDDO-Me in Inhibiting Proliferation of Ovarian Cancer Cells.
Neoplasms
HSP90 is a promising target in gemcitabine and 5-fluorouracil resistant pancreatic cancer.
Neoplasms
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.
Neoplasms
Hsp90 is an essential regulator of EphA2 receptor stability and signaling: implications for cancer cell migration and metastasis.
Neoplasms
HSP90 is essential for Jak-STAT signaling in classical Hodgkin lymphoma cells.
Neoplasms
Hsp90 is essential for restoring cellular functions of temperature-sensitive p53 mutant protein but not for stabilization and activation of wild-type p53: implications for cancer therapy.
Neoplasms
Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin.
Neoplasms
HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion.
Neoplasms
Hsp90 modulates CAG repeat instability in human cells.
Neoplasms
Hsp90 molecular chaperone inhibitors: are we there yet?
Neoplasms
HSP90 Molecular Chaperones, Metabolic Rewiring, and Epigenetics: Impact on Tumor Progression and Perspective for Anticancer Therapy.
Neoplasms
Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells.
Neoplasms
Hsp90 phosphorylation, Wee1, and the cell cycle.
Neoplasms
HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
Neoplasms
HSP90 proteins in the scenario of tumor complexity.
Neoplasms
Hsp90 regulates autophagy and plays a role in cancer therapy.
Neoplasms
Hsp90 regulates HDAC3-dependent gene transcription while HDAC3 regulates the functions of Hsp90.
Neoplasms
Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.
Neoplasms
Hsp90 structure and function studied by NMR spectroscopy.
Neoplasms
HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization.
Neoplasms
Hsp90, an unlikely ally in the war on cancer.
Neoplasms
Hsp90, the concertmaster: tuning transcription.
Neoplasms
Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.
Neoplasms
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.
Neoplasms
Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I.
Neoplasms
Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer.
Neoplasms
Hsp90-targeted miRNA-liposomal formulation for systemic antitumor effect.
Neoplasms
HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer.
Neoplasms
Hsp90: a chaperone for HIV-1.
Neoplasms
Hsp90: a chaperone for protein folding and gene regulation.
Neoplasms
Hsp90: a drug target?
Neoplasms
Hsp90: A Global Regulator of the Genotype-to-Phenotype Map in Cancers.
Neoplasms
Hsp90: a novel target for cancer therapy.
Neoplasms
Hsp90: a novel target for the disruption of multiple signaling cascades.
Neoplasms
HSP90: a promising broad-spectrum antiviral drug target.
Neoplasms
HSP90: a rising star on the horizon of anticancer targets.
Neoplasms
Hsp90: an emerging target for breast cancer therapy.
Neoplasms
Hsp90: breaking the symmetry.
Neoplasms
HSP90: Chaperone-me-not.
Neoplasms
Hsp90: the vulnerable chaperone.
Neoplasms
Hsp90? interacts with MDM2 to suppress p53-dependent senescence during skeletal muscle regeneration.
Neoplasms
Hsp90? promoted endothelial cell-dependent tumor angiogenesis in hepatocellular carcinoma.
Neoplasms
Hsp90? promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma.
Neoplasms
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors.
Neoplasms
Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation.
Neoplasms
HSP90B1 overexpression predicts poor prognosis in NSCLC patients.
Neoplasms
HSPA1A, HSPA1L and TRAP1 heat shock genes may be associated with prognosis in ovarian epithelial cancer.
Neoplasms
HSPA1L Enhances Cancer Stem Cell-Like Properties by Activating IGF1R? and Regulating ?-Catenin Transcription.
Neoplasms
HSPA9 overexpression inhibits apoptin-induced apoptosis in the HepG2 cell line.
Neoplasms
HSPB1 as a novel regulator of ferroptotic cancer cell death.
Neoplasms
Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.
Neoplasms
Human gamma delta T cells recognize heat shock protein-60 on oral tumor cells.
Neoplasms
Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines.
Neoplasms
Human heat shock protein 70 (Hsp70) as a peripheral membrane protein.
Neoplasms
Human Heat Shock Protein 70 Enhances Tumor Antigen Presentation through Complex Formation and Intracellular Antigen Delivery without Innate Immune Signaling.
Neoplasms
Human Hsp60 with its mitochondrial import signal occurs in solution as heptamers and tetradecamers remarkably stable over a wide range of concentrations.
Neoplasms
Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B.
Neoplasms
Human major histocompatibility complex contains genes for the major heat shock protein HSP70.
Neoplasms
Human meningiomas: immunohistochemical localization of progesterone receptor and heat shock protein 27 and absence of estrogen receptor and PS2.
Neoplasms
Human mitochondrial Hsp70 (mortalin): shedding light on ATPase activity, interaction with adenosine nucleotides, solution structure and domain organization.
Neoplasms
Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31.
Neoplasms
Human papillomavirus E6: Host cell receptor, GRP78, binding site prediction.
Neoplasms
Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70.
Neoplasms
Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70).
Neoplasms
Hybrid Nanoparticles Modified by Hyaluronic Acid Loading an HSP90 Inhibitor as a Novel Delivery System for Subcutaneous and Orthotopic Colon Cancer Therapy.
Neoplasms
Hydrating for resistance to radicicol.
Neoplasms
Hydroximic Acid Derivatives: Pleiotrophic Hsp Co-Inducers Restoring Homeostasis and Robustness.
Neoplasms
Hyperthermia by near infrared radiation induced immune cells activation and infiltration in breast tumor.
Neoplasms
Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition.
Neoplasms
Hypo-fractionated Radiation, Magnetic Nanoparticle Hyperthermia and a Viral Immunotherapy Treatment of Spontaneous Canine Cancer.
Neoplasms
Hypoxia attenuates Hsp90 inhibitor 17-DMAG-induced cyclin B1 accumulation in hepatocellular carcinoma cells.
Neoplasms
Hypoxia Enhances Lysophosphatidic Acid Responsiveness in Ovarian Cancer Cells and Lysophosphatidic Acid Induces Ovarian Tumor Metastasis In vivo.
Neoplasms
Hypoxia upregulates Hsp90? expression via STAT5b in cancer cells.
Neoplasms
Identification and characterisation of a novel heat shock protein 90 inhibitor ONO4140.
Neoplasms
Identification and characterization of a 66-68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells.
Neoplasms
Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60.
Neoplasms
Identification and Characterization of MortaparibPlus-A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Type p53-Dependent and -Independent Mechanisms.
Neoplasms
Identification and Comparison of Differentiation-Related Proteins in Hepatocellular Carcinoma Tissues by Proteomics.
Neoplasms
Identification and functional characterization of nuclear mortalin in human carcinogenesis.
Neoplasms
Identification and Structure-Activity Studies of 1,3-Dibenzyl-2-aryl imidazolidines as Novel Hsp90 Inhibitors.
Neoplasms
Identification of a new scaffold for hsp90 C-terminal inhibition.
Neoplasms
Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization.
Neoplasms
Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor.
Neoplasms
Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.
Neoplasms
Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.
Neoplasms
Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma.
Neoplasms
Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry.
Neoplasms
Identification of DU 145 prostate cancer cell proteins that bind to the carboxy-terminal peptide of human PTHrP in vitro.
Neoplasms
Identification of epipolythiodioxopiperazines HDN-1 and chaetocin as novel inhibitor of heat shock protein 90.
Neoplasms
Identification of GRP75 as an independent favorable prognostic marker of neuroblastoma by a proteomics analysis.
Neoplasms
Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library.
Neoplasms
Identification of Heat Shock Protein 90 as a Recurrence Related Marker in Juvenile Nasopharyngeal Angiofibroma.
Neoplasms
Identification of heat shock protein 90 inhibitors to sensitize drug resistant side population tumor cells using a cell based assay platform.
Neoplasms
Identification of HLA-A2 or HLA-A24-restricted CTL epitopes for potential HSP105-targeted immunotherapy in colorectal cancer.
Neoplasms
Identification of Inhibitors of HSF1 Functional Activity by High-Content Target-Based Screening.
Neoplasms
Identification of Isoform-Selective Ligands for the Middle Domain of Heat Shock Protein 90 (Hsp90).
Neoplasms
Identification of Limonol Derivatives as Heat Shock Protein?90 (Hsp90) Inhibitors through a Multidisciplinary Approach.
Neoplasms
Identification of low-abundance proteins in serum via the isolation of HSP72 complexes.
Neoplasms
Identification of metastasis-related proteins and their clinical relevance to triple-negative human breast cancer.
Neoplasms
Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA.
Neoplasms
Identification of mixed lineage leukemia 1(MLL1) protein as a coactivator of heat shock factor 1(HSF1) protein in response to heat shock protein 90 (HSP90) inhibition.
Neoplasms
Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma.
Neoplasms
Identification of mRNAs differentially expressed in lymphocytes following interleukin-2 activation.
Neoplasms
Identification of new biomarkers for clinical trials of Hsp90 inhibitors.
Neoplasms
Identification of New Hsp90 Inhibitors: Structure Based Virtual Screening, Molecular Dynamic Simulation, Synthesis and Biological Evaluation.
Neoplasms
Identification of Novel Interaction Partners of AIF Protein on the Outer Mitochondrial Membrane.
Neoplasms
Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants.
Neoplasms
Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.
Neoplasms
Identification of Potential Anticancer Protein Targets in Cytotoxicity Mediated by Tropical Medicinal Fern Extracts.
Neoplasms
Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer.
Neoplasms
Identification of the circRNA-miRNA-mRNA regulatory network of Hsp90 inhibitor-induced cell death in colorectal cancer by integrated analysis.
Neoplasms
Identification of the naphthoquinone derivative inhibitors binding site in heat shock protein 90: an induced-fit docking, molecular dynamics and 3D-QSAR study.
Neoplasms
Identification of the peptide-binding site in the heat shock chaperone/tumor rejection antigen gp96 (Grp94).
Neoplasms
Identification of the phosphorylation sites of the murine small heat shock protein hsp25.
Neoplasms
Identification of the plant compound geraniin as a novel hsp90 inhibitor.
Neoplasms
Identification of the Transmembrane Glucose Regulated Protein 78 as a Biomarker for the Brain Cancer Glioblastoma Multiforme by Gene Expression and Proteomic Studies.
Neoplasms
Identification of TPD52 and DNAJB1 as two novel bile biomarkers for cholangiocarcinoma by iTRAQ?based quantitative proteomics analysis.
Neoplasms
Identification of Tumor Antigen AF20 as Glycosylated Transferrin Receptor 1 in Complex with Heat Shock Protein 90 and/or Transporting ATPase.
Neoplasms
Identification of tumor antigens that elicit a humoral immune response in breast cancer patients' sera by serological proteome analysis (SERPA).
Neoplasms
Identification of tumor necrosis factor signaling-related proteins during Epstein-Barr virus-induced B cell transformation.
Neoplasms
Identification, design and bio-evaluation of novel Hsp90 inhibitors by ligand-based virtual screening.
Neoplasms
Identifications small molecules inhibitor of p53-mortalin complex for cancer drug using virtual screening.
Neoplasms
Ifosfamide induced stress response in human lymphocytes.
Neoplasms
IgA antibodies to the 27-kDa heat-shock protein in the genital tracts of women with gynecologic cancers.
Neoplasms
IGFBP2 plays an important role in heat shock protein 27-mediated cancer progression and metastasis.
Neoplasms
IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.
Neoplasms
IL-6 activated JAK/STAT3 pathway and sensitivity to Hsp90 inhibitors in multiple myeloma.
Neoplasms
Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model.
Neoplasms
Image-Guided Radiofrequency Hyperthermia (RFH)-Enhanced Direct Chemotherapy of Hepatic Tumors: The Underlying Biomolecular Mechanisms.
Neoplasms
Imaging Mass Spectrometry and Proteome Analysis of Marek's Disease Virus-Induced Tumors.
Neoplasms
Imaging of Firefly Luciferase Activity under Antiangiogenic Therapy in a Heat Shock Protein 70-Transfected Melanoma Tumor Model.
Neoplasms
Immortal and mortal clonal lymphocyte lines from channel catfish: comparison of telomere length, telomerase activity, tumor suppressor and heat shock protein expression.
Neoplasms
Immune expression and inhibition of heat shock protein 90 in uveal melanoma.
Neoplasms
Immune mechanism of the antitumor effects generated by bortezomib.
Neoplasms
Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.
Neoplasms
Immunization of cancer patients with autologous cancer-derived heat shock protein gp96 preparations: a pilot study.
Neoplasms
Immunization with a recombinant GnRH vaccine conjugated to heat shock protein 65 inhibits tumor growth in orthotopic prostate cancer mouse model.
Neoplasms
Immunization with a recombinant GnRH vaccine fused to heat shock protein 65 inhibits mammary tumor growth in vivo.
Neoplasms
Immunization with heat shock protein 105-pulsed dendritic cells leads to tumor rejection in mice.
Neoplasms
Immunization with heat shock protein 70 from methylcholanthrene-induced sarcomas induces tumor protection correlating with in vitro T cell responses.
Neoplasms
Immuno-hyperthermia effected by antibody-conjugated nanoparticles selectively targets and eradicates individual cancer cells.
Neoplasms
Immunocytochemical accumulation of p53 in corticotroph adenomas: relationship with heat shock proteins and apoptosis.
Neoplasms
Immunoelectron microscopy provides evidence for the presence of mitochondrial heat shock 10-kDa protein (chaperonin 10) in red blood cells and a variety of secretory granules.
Neoplasms
Immunoexpression patterns for Hypoxia-inducible Factor-1? and von Hippel-Lindau protein, in relation to Hsp90, of human brain tumors.
Neoplasms
Immunogenic hsp-70 is overexpressed in colorectal cancers with high-degree microsatellite instability.
Neoplasms
Immunogenic potential of three transmissible venereal tumor cell lysates to prime canine-dendritic cells for cancer immunotherapy.
Neoplasms
Immunohistochemical Analysis of Expressions of RB1, CDK4, HSP90, cPLA2G4A, and CHMP2B Is Helpful in Distinction between Myxofibrosarcoma and Myxoid Liposarcoma.
Neoplasms
Immunohistochemical detection of estrogen receptor in invasive human breast cancer: correlation with heat shock proteins, pS2 and oncogene products.
Neoplasms
Immunohistochemical detection of HSP27 and hnRNP K as prognostic and predictive biomarkers for colorectal cancer.
Neoplasms
Immunohistochemical detection of HSP60-expression in human ovarian cancer. Correlation with survival in a series of 247 patients.
Neoplasms
Immunohistochemical detection of the 150-kDa oxygen-regulated protein in bladder cancer.
Neoplasms
Immunohistochemical distribution of heat shock protein 47 (HSP47) in scirrhous carcinoma of the stomach.
Neoplasms
Immunohistochemical evaluation of expression of heat shock proteins HSP70 and HSP90 in mammary gland neoplasms in bitches.
Neoplasms
Immunohistochemical Evaluation of Heat Shock Protein Expression in Normal Canine Nerve and Peripheral Nerve Sheath Tumours.
Neoplasms
Immunohistochemical evaluation of heat shock proteins in normal and preinvasive lesions of the cervix.
Neoplasms
Immunohistochemical expression of Hsp60 correlates with tumor progression and hormone resistance in prostate cancer.
Neoplasms
Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production.
Neoplasms
Immunohistochemical tumour markers in endometrial carcinoma.
Neoplasms
Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47.
Neoplasms
Immunohistochemistry of human Hsp60 in health and disease: from autoimmunity to cancer.
Neoplasms
Immunohistochemistry of Human Hsp60 in Health and Disease: From Autoimmunity to Cancer.
Neoplasms
Immunolocalisation of heat shock protein 72 and glycoprotein 96 in colonic adenocarcinoma.
Neoplasms
Immunomodulating activity of mycobacterial heat shock protein 65 in tumor cells.
Neoplasms
Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer.
Neoplasms
Immunopathogenic consequences of Chlamydia trachomatis 60 kDa heat shock protein expression in the female reproductive tract.
Neoplasms
Immunoprotective activities of multiple chaperone proteins isolated from murine B-cell leukemia/lymphoma.
Neoplasms
Immunotherapeutic targeting of membrane hsp70-expressing tumors using recombinant human granzyme B.
Neoplasms
Immunotherapy of a human papillomavirus (HPV) type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guérin (BCG) hsp65 and HPV16 E7.
Neoplasms
Immunotherapy of cancer using heat shock proteins.
Neoplasms
Immunotherapy of radioresistant mammary tumors with early metastasis using molecular chaperone vaccines combined with ionizing radiation.
Neoplasms
Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations.
Neoplasms
Impact of butyrate on PKM2 and HSP90? expression in human colon tissues of different transformation stages: a comparison of gene and protein data.
Neoplasms
Impact of heat-shock protein 90 on cancer metastasis.
Neoplasms
Impact of nitrite exposure on plasma biochemical parameters and immune-related responses in Takifugu rubripes.
Neoplasms
Impact of Posttranslational Modifications on the Anticancer Activity of Hsp90 Inhibitors.
Neoplasms
Impairment of Membrane Lipid Homeostasis by Bichalcone Analog TSWU-BR4 Attenuates Function of GRP78 in Regulation of the Oxidative Balance and Invasion of Cancer Cells.
Neoplasms
Implication of Heat Shock Protein 90 (HSP90) in Tumor Angiogenesis: A Molecular Target for Anti-Angiogenic Therapy?
Neoplasms
Implication of heat shock proteins in rotavirus entry into Reh cells.
Neoplasms
Implication of PBP74/mortalin/GRP75 in the radio-adaptive response.
Neoplasms
Improvement of inhibitor identification for heat shock protein 90? by utilizing a red-shifted fluorescence polarization probe.
Neoplasms
Improvements in the growth performance, immunity, disease resistance, and gut microbiota by the probiotic Rummeliibacillus stabekisii in Nile tilapia (Oreochromis niloticus).
Neoplasms
Improving the Hsp90 Inhibitors Containing 4-(2,4-Dihydroxyphenyl)-1,2,3-thiadiazole Scaffold: Synthesis, Affinity and Effect on Cancer Cells.
Neoplasms
Improving the outcome of patients with castration-resistant prostate cancer through rational drug development.
Neoplasms
In silico Analysis of Molecular Mechanisms of Galanthus nivalis Agglutinin-Related Lectin-Induced Cancer Cell Death from Carbohydrate-Binding Motif Evolution Hypothesis.
Neoplasms
In silico analysis of the binding properties of solasonine to mortalin and p53, and in vitro pharmacological studies of its apoptotic and cytotoxic effects on human HepG2 and Hep3b hepatocellular carcinoma cells.
Neoplasms
In silico design novel Vibsanin B derivatives as inhibitor for heat shock protein 90 based on 3D-QSAR, molecular docking and molecular dynamics simulation.
Neoplasms
In silico design of small peptide-based Hsp90 inhibitor: A novel anticancer agent.
Neoplasms
In silico evaluation of drugs used in treatment of oral lichen planus.
Neoplasms
In silico identification of potential Hsp90 inhibitors via ensemble docking, DFT and molecular dynamics simulations.
Neoplasms
In silico screening and exploration into phenotypic alterations of deleterious oncogenic single nucleotide polymorphisms in HSPB1 gene.
Neoplasms
In vitro and in vivo efficacy of heat shock protein specific immunotoxins on human tumor cells.
Neoplasms
In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors.
Neoplasms
In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study.
Neoplasms
In Vitro Metabolism of BIIB021, an Inhibitor of Heat Shock Protein 90, in Liver Microsomes and Hepatocytes of Rats, Dogs, and Humans and Recombinant Human Cytochrome P450 Isoforms.
Neoplasms
In vivo imaging of CT26 mouse tumors by using cmHsp70.1 monoclonal antibody.
Neoplasms
In Vivo Method to Monitor Changes in HER2 Expression Using Near-Infrared Fluorescence Imaging.
Neoplasms
In vivo method to monitor changes in HER2 expression using near-infrared fluorescence imaging.
Neoplasms
In vivo production of heat shock protein in mouse peritoneal macrophages by administration of lipopolysaccharide.
Neoplasms
In vivo-in vitro correlation of antitumor activity of heat shock protein 90 (HSP90) inhibitors with a pharmacokinetics/pharmacodynamics analysis using NCI-N87 xenograft mice.
Neoplasms
In-vivo fluorescence lifetime imaging for monitoring the efficacy of the cancer treatment.
Neoplasms
Inactivation of a redox-sensitive protein phosphatase during the early events of tumor necrosis factor/interleukin-1 signal transduction.
Neoplasms
Increase in gene-transcript levels as indicators of up-regulation of the unfolded protein response in spontaneous canine tumors.
Neoplasms
Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors.
Neoplasms
Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction.
Neoplasms
Increased expression of 70 kD heat shock protein in cultured primary human keratinocytes induced by human papillomavirus 16 E6/E7 gene.
Neoplasms
Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma.
Neoplasms
Increased Expression of GRP78 in Recurrent GBM Patients.
Neoplasms
Increased expression of HSP27 inhibits invasion and metastasis in human esophageal squamous cell carcinoma.
Neoplasms
Increased expression of the major heat shock protein Hsp72 in human prostate carcinoma cells is dispensable for their viability but confers resistance to a variety of anticancer agents.
Neoplasms
Increased inducible heat shock protein 72 expression associated with PBMC isolated from patients with haematological tumours.
Neoplasms
Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability.
Neoplasms
Increased production of tumor necrosis factor-alpha by peritoneal fluid mononuclear cells induced by 60-kDa heat shock protein in women with minimal to mild endometriosis.
Neoplasms
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990.
Neoplasms
Increased sensitivity of human colon cancer cells to DNA cross-linking agents after GRP78 up-regulation.
Neoplasms
Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein.
Neoplasms
Indolyl-chalcone derivatives induce hepatocellular carcinoma cells apoptosis through oxidative stress related mitochondrial pathway in vitro and in vivo.
Neoplasms
Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors.
Neoplasms
Inducible heat shock protein 70 prevents multifocal flat dysplastic lesions and invasive tumors in an inflammatory model of colon cancer.
Neoplasms
Inducible heat shock protein 70, interleukin-18, and tumor necrosis factor alpha correlate with outcomes in spontaneous intracerebral hemorrhage.
Neoplasms
Inducible heat shock protein A1A (HSPA1A) is markedly expressed in rat myometrium by labour and secreted via myometrial cell-derived extracellular vesicles.
Neoplasms
Inducible HSP70 antagonizes cisplatin?induced cell apoptosis through inhibition of the MAPK signaling pathway in HGC?27 cells.
Neoplasms
Inducible Hsp70 as target of anticancer immunotherapy: Identification of HLA-A*0201-restricted epitopes.
Neoplasms
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Neoplasms
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78.
Neoplasms
Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthase.
Neoplasms
Induction of apoptosis by luteolin involving akt inactivation in human 786-o renal cell carcinoma cells.
Neoplasms
Induction of apoptosis by phenylisocyanate derivative of quercetin: involvement of heat shock protein.
Neoplasms
Induction of autologous tumor killing by heat treatment of fresh human tumor cells: involvement of gamma delta T cells and heat shock protein 70.
Neoplasms
Induction of cyclooxygenase-2 by heat shock protein 60 in macrophages and endothelial cells.
Neoplasms
Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-epsilon/ERK/AP-1 signaling cascade.
Neoplasms
Induction of Heat Shock Protein 70 as a Predictive Marker of the Tumor Cell Radiosensitization with Inhibitors of the Heat Shock Protein 90 Activity.
Neoplasms
Induction of heat shock protein 72 synthesis by endogenous tumor necrosis factor via enhancement of the heat shock element-binding activity of heat shock factor 1.
Neoplasms
Induction of heat shock protein HSPA6 (HSP70B') upon HSP90 inhibition in cancer cell lines.
Neoplasms
Induction of heat shock protein synthesis in murine tumors during the development of thermotolerance.
Neoplasms
Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth.
Neoplasms
Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation.
Neoplasms
Induction of Hsp70 in tumor cells treated with inhibitors of the Hsp90 activity: A predictive marker and promising target for radiosensitization.
Neoplasms
Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases.
Neoplasms
Induction of human hsp60 expression in monocytic cell lines.
Neoplasms
Induction of leukemia-specific antibodies by immunotherapy with leukemia-cell-derived heat shock protein 70.
Neoplasms
Induction of multiple CD8+ T cell responses against the inducible Hsp70 employing an Hsp70 oligoepitope peptide.
Neoplasms
Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin.
Neoplasms
Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells.
Neoplasms
Induction of novel Grp75 isoforms by 2-deoxyglucose in human and murine fibroblasts.
Neoplasms
Induction of premature senescence by hsp90 inhibition in small cell lung cancer.
Neoplasms
Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
Neoplasms
Induction of synthesis of heat shock protein 72 in tumor necrosis factor gene-transduced cells.
Neoplasms
Induction of systemic antitumor immunity by gene transfer of mammalian heat shock protein 70.1 into tumors in situ.
Neoplasms
Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors.
Neoplasms
Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice.
Neoplasms
Inflammation is associated with progression of actinic keratoses to squamous cell carcinomas in humans.
Neoplasms
Inflammation Profiling of Critically Ill Coronavirus Disease 2019 Patients.
Neoplasms
Inflammation, genetics, and ischemic heart disease: focus on the major histocompatibility complex (MHC) genes.
Neoplasms
Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.
Neoplasms
Inflammation-induced protein carbonylation contributes to poor prognosis for cholangiocarcinoma.
Neoplasms
Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.
Neoplasms
Influence of drug-induced apoptotic death on processing and presentation of tumor antigens by dendritic cells.
Neoplasms
Influence of ezrin-shRNA in combination with HSP70 on the apoptosis and proliferation of osteosarcoma cells.
Neoplasms
Influence of sex on cytokines, heat shock protein and oxidative stress markers in response to an acute total body resistance exercise protocol.
Neoplasms
Influenza virus infection elicits protective antibodies and T cells specific for host cell antigens also expressed as tumor-associated antigens: a new view of cancer immunosurveillance.
Neoplasms
Inhibiting HSP90 to treat cancer: a strategy in evolution.
Neoplasms
Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells.
Neoplasms
Inhibiting protein-protein interactions of Hsp90 as a novel approach for targeting cancer.
Neoplasms
Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.
Neoplasms
Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.
Neoplasms
Inhibiting the molecular evolution of cancer through HSP90.
Neoplasms
Inhibition effects on liver tumors of BALB/c mice bearing H22 cells by immunization with a recombinant immunogen of GnRH linked to heat shock protein 65.
Neoplasms
Inhibition of ALK, PI3K/MEK and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene.
Neoplasms
Inhibition of Androgen Receptor Expression with Small Interfering RNA Enhances Cancer Cell Apoptosis by Suppressing Survival Factors in Androgen Insensitive, Late Stage LNCaP Cells.
Neoplasms
Inhibition of Cancer Cell Growth by GRP78 siRNA Lipoplex via Activation of Unfolded Protein Response.
Neoplasms
Inhibition of Cancer Invasion and Metastasis by Targeting the Molecular Chaperone Heat-shock Protein 90.
Neoplasms
Inhibition of constitutive and cxc-chemokine-induced NF-kappaB activity potentiates ansamycin-based HSP90-inhibitor cytotoxicity in castrate-resistant prostate cancer cells.
Neoplasms
Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2? pathway.
Neoplasms
Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer.
Neoplasms
Inhibition of Established Micrometastases by Targeted Drug Delivery via Cell Surface Associated GRP78.
Neoplasms
Inhibition of gastric tumor growth by a novel Hsp90 inhibitor.
Neoplasms
Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives.
Neoplasms
Inhibition of heat shock protein (Hsp) 27 potentiates the suppressive effect of Hsp90 inhibitors in targeting breast cancer stem-like cells.
Neoplasms
Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4'fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells.
Neoplasms
Inhibition of heat shock protein (HSP) 90 reverses signal transducer and activator of transcription (STAT) 3-mediated muscle wasting in cancer cachexia mice.
Neoplasms
Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers.
Neoplasms
Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers.
Neoplasms
Inhibition of Heat Shock Protein 90 as a Novel Platform for the Treatment of Cancer.
Neoplasms
Inhibition of heat shock protein 90 decreases ACTH production and cell proliferation in AtT-20 cells.
Neoplasms
Inhibition of heat shock protein 90 exerts an antitumour effect in angiosarcoma: involvement of the vascular endothelial growth factor signalling pathway.
Neoplasms
Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
Neoplasms
Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol.
Neoplasms
Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
Neoplasms
Inhibition of heat shock protein 90 sensitizes melanoma cells to thermosensitive ferromagnetic particle-mediated hyperthermia with low Curie temperature.
Neoplasms
Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.
Neoplasms
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription.
Neoplasms
Inhibition of Heat Shock Protein 90 with AUY922 Represses Tumor Growth in a Transgenic Mouse Model of Islet Cell Neoplasms.
Neoplasms
Inhibition of heat shock protein-90 modulates multiple functions required for survival of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells.
Neoplasms
Inhibition of histone deacetylation and DNA methylation improves gene expression mediated by the adeno-associated virus/phage in cancer cells.
Neoplasms
Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
Neoplasms
Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone.
Neoplasms
Inhibition of HSP90 and Activation of HSF1 Diminish Macrophage NLRP3 Inflammasome Activity in Alcohol-Associated Liver Injury.
Neoplasms
Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond.
Neoplasms
Inhibition of hsp90 compromises the DNA damage response to radiation.
Neoplasms
Inhibition of HSP90 could be possible mechanism for anti-cancer property of amniotic membrane.
Neoplasms
Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel.
Neoplasms
Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma.
Neoplasms
Inhibition of HSP90 molecular chaperones: moving into the clinic.
Neoplasms
Inhibition of HSP90 overcomes melphalan resistance through downregulation of Src in multiple myeloma cells.
Neoplasms
Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma.
Neoplasms
Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.
Neoplasms
Inhibition of HSP90 with AUY922 Induces Synergy in HER2-Amplified Trastuzumab-Resistant Breast and Gastric Cancer.
Neoplasms
Inhibition of Hsp90 with resorcylic acid macrolactones: synthesis and binding studies.
Neoplasms
Inhibition of Hsp90: a multitarget approach to radiosensitization.
Neoplasms
Inhibition of HSP90? Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System.
Neoplasms
Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses.
Neoplasms
Inhibition of mortalin expression reverses cisplatin resistance and attenuates growth of ovarian cancer cells.
Neoplasms
Inhibition of NF-kappaB1 and NF-kappaB2 activation in prostate cancer cells treated with antibody against the carboxyl terminal domain of GRP78: effect of p53 upregulation.
Neoplasms
Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells.
Neoplasms
Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach.
Neoplasms
Inhibition of the mitochondrial Hsp90 chaperone network: A novel, efficient treatment strategy for cancer?
Neoplasms
Inhibition of the serine/threonine protein phosphatases PP1 and PP2A in lymphocytes: effect on mRNA levels for interleukin-2, IL-2R alpha, krox-24, p53, hsc70 and cyclophilin.
Neoplasms
Inhibition of tumor growth in mice with severe combined immunodeficiency is mediated by heat shock protein 70 (Hsp70)-peptide-activated, CD94 positive natural killer cells.
Neoplasms
Inhibitor of heat-shock protein 90 enhances the antitumor effect of DNA vaccine targeting clients of heat-shock protein.
Neoplasms
Inhibitors of deacetylases suppress oncogenic KIT signaling, acetylate HSP90, and induce apoptosis in gastrointestinal stromal tumors.
Neoplasms
Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth.
Neoplasms
Inhibitors of HSP90 in melanoma.
Neoplasms
Inhibitors of the HSP90 molecular chaperone: attacking the master regulator in cancer.
Neoplasms
Inhibitors of the HSP90 molecular chaperone: current status.
Neoplasms
Inhibitory effect of Par-4 combined with cisplatin on human Wilms' tumor cells.
Neoplasms
Inhibitory effect of STAT3 gene combined with CDDP on growth of human Wilms tumour SK-NEP-1 cells.
Neoplasms
Inhibitory effects of heat shock protein 90 blockade on proinflammatory human Th1 and Th17 cell subpopulations.
Neoplasms
Initial testing (stage 1) of ganetespib, an Hsp90 inhibitor, by the pediatric preclinical testing program.
Neoplasms
Innate immunity meets with cellular stress at the IKK complex: Regulation of the IKK complex by HSP70 and HSP90.
Neoplasms
Innate immunity protein Tag7 (PGRP-S) activates lymphocytes capable of Fasl-Fas-dependent contact killing of virus-infected cells.
Neoplasms
Insights from yeast into whether the inhibition of heat shock transcription factor (Hsf1) by rapamycin can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor.
Neoplasms
Insights into designing the dual-targeted HER2/HSP90 inhibitors.
Neoplasms
Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers.
Neoplasms
Insulin resistance contributes to multidrug resistance in HepG2 cells via activation of the PERK signaling pathway and upregulation of Bcl-2 and P-gp.
Neoplasms
Insulin-degrading enzyme (IDE): a novel heat shock-like protein.
Neoplasms
Integration of a porous coordination network and black phosphorus nanosheets for improved photodynamic therapy of tumor.
Neoplasms
Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target.
Neoplasms
Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients.
Neoplasms
Interaction between HSP60 and {beta}-catenin promotes metastasis.
Neoplasms
Interaction between hsp70 and hsp40, eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53.
Neoplasms
Interaction of hepatitis C virus core protein with Hsp60 triggers the production of reactive oxygen species and enhances TNF-alpha-mediated apoptosis.
Neoplasms
Interaction of Marek's disease virus oncoprotein Meq with heat-shock protein 70 in lymphoid tumour cells.
Neoplasms
Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones.
Neoplasms
Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function.
Neoplasms
Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response.
Neoplasms
Interaction with Ribosomal Proteins Accompanies Stress Induction of the Anticancer Metallodrug BOLD-100/KP1339 in the Endoplasmic Reticulum.
Neoplasms
Interactions between Hsp90 and oncogenic viruses: implications for viral cancer therapeutics.
Neoplasms
Interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) are necessary in the early stages of induction of CD4 and CD8 cytotoxic T cells by Mycobacterium leprae heat shock protein (hsp) 65 kD.
Neoplasms
Interleukin 1 and tumor necrosis factor stimulate two novel protein kinases that phosphorylate the heat shock protein hsp27 and beta-casein.
Neoplasms
Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein. Effects in fibroblasts, Hep G2 and U937 cells.
Neoplasms
Interleukin-6, interleukin-10 and heat shock protein-90 expression in renal epithelial neoplasias and surrounding normal-appearing renal parenchyma.
Neoplasms
INTERMITTENT AND SUSTAINED HYPOXIA INDUCE A SIMILAR GENE EXPRESSION PROFILE IN THE HUMAN AORTIC ENDOTHELIAL CELLS.
Neoplasms
Intracellular trafficking and endocytic uptake pathway of Pepper vein banding virus-like particles in epithelial cells.
Neoplasms
Intratumor injection of the Hsp90 inhibitor 17AAG decreases tumor growth and induces apoptosis in a prostate cancer xenograft model.
Neoplasms
Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors.
Neoplasms
Intrinsic proteotoxic stress levels vary and act as a predictive marker for sensitivity of cancer cells to Hsp90 inhibition.
Neoplasms
Introducing differential expression of human heat shock protein 27 in hepatocellular carcinoma: moving toward identification of cancer biomarker.
Neoplasms
Intronic polymorphism (1541-1542delGT) of the constitutive heat shock protein 70 gene has functional significance and shows evidence of association with lung cancer risk.
Neoplasms
Investigation into the potential for hypoxic interior of neoplasms to enhance HSPA expression in glioma.
Neoplasms
Investigation of anticancer activities of STA-9090 (ganetespib) as a second generation HSP90 inhibitor in Saos-2 osteosarcoma cells.
Neoplasms
Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.
Neoplasms
Investigation of Thermally Induced Cellular Ablation and Heat Response Triggered by Planar MoS2-Based Nanocomposite.
Neoplasms
Investigation on different chemical stability of mitochondrial Hsp60 and its precursor.
Neoplasms
Involvement and Targeted Intervention of Mortalin-Regulated Proteome Phosphorylated-Modification in Hepatocellular Carcinoma.
Neoplasms
Involvement of HSP90 in ischemic postconditioning-induced cardioprotection by inhibition of the complement system, JNK and inflammation.
Neoplasms
Involvement of p38 mitogen-activated protein kinase in heat shock protein 27 induction in human neutrophils.
Neoplasms
Involvement of PAR-4 in cannabinoid-dependent sensitization of osteosarcoma cells to TRAIL-induced apoptosis.
Neoplasms
Involvement of peptide antigens in the cytotoxicity between 70-kDa heat shock cognate protein-like molecule and CD3+, CD4-, CD8-, TCR-alpha beta- killer T cells.
Neoplasms
Involvement of the TRAP-1 homologue, Dd-TRAP1, in spore differentiation during Dictyostelium development.
Neoplasms
Ion-permeable membrane for on-chip preconcentration and separation of cancer marker proteins.
Neoplasms
Ionizing radiation improves glioma-specific targeting of superparamagnetic iron oxide nanoparticles conjugated with cmHsp70.1 monoclonal antibodies (SPION-cmHsp70.1).
Neoplasms
IP6K2 is a client for HSP90 and a target for cancer therapeutics development.
Neoplasms
IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells.
Neoplasms
Iron-oxide nanoparticles target intracellular HSP90 to induce tumor radio-sensitization.
Neoplasms
Is the small heat shock protein alphaB-crystallin an oncogene?
Neoplasms
Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.
Neoplasms
Isolation and characterization of a novel GRP78-specific single-chain variable fragment (scFv) using ribosome display method.
Neoplasms
Isolation and characterization of a novel nanobody for detection of GRP78 expressing cancer cells.
Neoplasms
Isolation and characterization of a novel scFv antibody fragments specific for Hsp70 as a tumor biomarker.
Neoplasms
Isolation of MHC class I-restricted tumor antigen peptide and its precursors associated with heat shock proteins hsp70, hsp90, and gp96.
Neoplasms
Isotope tracing assisted metabolic profiling: Application to understanding HSP60 silencing mediated tumor progression.
Neoplasms
Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors.
Neoplasms
Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction.
Neoplasms
iTRAQ Quantitative Proteomic Comparison of Metastatic and Non-Metastatic Uveal Melanoma Tumors.
Neoplasms
JNK pathway and heat shock response mediate the survival of C26 colon carcinoma bearing mice fed with the mushroom Pleurotus eryngii var. eryngii without affecting tumor growth or cachexia.
Neoplasms
KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance.
Neoplasms
KEGG-expressed genes and pathways in triple negative breast cancer: Protocol for a systematic review and data mining.
Neoplasms
KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules.
Neoplasms
KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78.
Neoplasms
Kidney injury and alterations of inflammatory cytokine expressions in mice following long-term exposure to cerium chloride.
Neoplasms
Kill and spread the word: stimulation of antitumor immune responses in the context of radiotherapy.
Neoplasms
Killing of normal melanocytes, combined with heat shock protein 70 and CD40L expression, cures large established melanomas.
Neoplasms
Kinetic and structural characterization of human mortalin.
Neoplasms
Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia.
Neoplasms
Knockdown of lncRNA ZNRD1-AS1 suppresses gastric cancer cell proliferation and metastasis by targeting the miR-9-5p/HSP90AA1 axis.
Neoplasms
Knockdown of microRNA-29a Changes the Expression of Heat Shock Proteins in Breast Carcinoma MCF-7 Cells.
Neoplasms
Korean ginseng extract ameliorates abnormal immune response through the regulation of inflammatory constituents in Sprague Dawley rat subjected to environmental heat stress.
Neoplasms
KU135, a Novel Novobiocin-derived C-terminal Inhibitor of Hsp90, Exerts Potent Antiproliferative Effects in Human Leukemic Cells.
Neoplasms
KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90? in Prostate Cancer Cells.
Neoplasms
Label-free LC-MSe in tissue and serum reveals protein networks underlying differences between benign and malignant serous ovarian tumors.
Neoplasms
Lactobacilli Modulate Hypoxia-Inducible Factor (HIF)-1 Regulatory Pathway in Triple Negative Breast Cancer Cell Line.
Neoplasms
Landscape of the mitochondrial Hsp90 metabolome in tumours.
Neoplasms
Lapatinib resistance in HER2+ cancers: latest findings and new concepts on molecular mechanisms.
Neoplasms
Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.
Neoplasms
Lead identification of ?-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90.
Neoplasms
Lectin, galactoside-binding soluble 3 binding protein promotes 17-N-Allylamino-17-demethoxygeldanamycin resistance through PI3K/Akt pathway in lung cancer cell line.
Neoplasms
Lectin-like oxidized low-density lipoprotein receptor-1 delivers heat shock protein 60-fused antigen into the MHC class I presentation pathway.
Neoplasms
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer.
Neoplasms
Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity.
Neoplasms
Leptin improves the in vitro development of preimplantation rabbit embryos under oxidative stress of cryopreservation.
Neoplasms
Lessons from Cancer: Subcellular Drug Targeting of Mitochondrial Hsp90 in Pulmonary Arterial Hypertension.
Neoplasms
Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens.
Neoplasms
Ligand Binding, Unbinding and Allosteric Effects: Deciphering Small-Molecule Modulation of HSP90.
Neoplasms
Ligand-targeted theranostic nanomedicines against cancer.
Neoplasms
Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis.
Neoplasms
Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells.
Neoplasms
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Neoplasms
Linking hsp90's role as an evolutionary capacitator to the development of cancer.
Neoplasms
Lipopolysaccharide-free heat shock protein 60 activates T cells.
Neoplasms
Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis.
Neoplasms
Liposomal quercetin efficiently suppresses growth of solid tumors in murine models.
Neoplasms
Liver dual arterial blood supply maintains liver regeneration: Analysis of signaling pathways in rats.
Neoplasms
Liver metabolic disruption induced after a single exposure to PCB126 in rats.
Neoplasms
LncRNA-TP53TG1 Participated in the Stress Response Under Glucose Deprivation in Glioma.
Neoplasms
Local radiotherapy increases the level of autoantibodies to ribosomal P0 protein but not to heat shock proteins, extracellular matrix molecules and EGFR/ErbB2 receptors in prostate cancer patients.
Neoplasms
Localization and significance of molecular chaperones, heat shock protein 1, and tumor rejection antigen gp96 in the male reproductive tract and during capacitation and acrosome reaction.
Neoplasms
Localization of heat shock protein 110 in canine mammary gland tumors.
Neoplasms
Long non-coding RNA NKILA regulates expression of HSP90?, NF-?B and ?-catenin proteins in the MCF-7 breast cancer cell line.
Neoplasms
Long-term effect of heat shock protein 60 from Actinobacillus actinomycetemcomitans on epithelial cell viability and mitogen-activated protein kinases.
Neoplasms
Long-term protection against HPV E7-positive tumor by a single vaccination of AAV vectors encoding a fusion protein of inactivated E7 of HPV 16/18 and heat shock protein 70.
Neoplasms
Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation.
Neoplasms
Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type.
Neoplasms
Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells.
Neoplasms
Low dose HSP90 inhibition with AUY922 blunts rapid evolution of metastatic and drug resistant phenotypes induced by TGF-? and paclitaxel in A549 cells.
Neoplasms
Low intensity focused ultrasound (LOFU) modulates unfolded protein response and sensitizes prostate cancer to 17AAG.
Neoplasms
Low-Dose Hsp90 Inhibitor Selectively Radiosensitizes HNSCC and Pancreatic Xenografts.
Neoplasms
Low-dose Hsp90 inhibitors tumor-selectively sensitize bladder cancer cells to chemoradiotherapy.
Neoplasms
LOXL1?AS1 promotes thymoma and thymic carcinoma progression by regulating miR?525?5p?HSPA9.
Neoplasms
LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.
Neoplasms
Lymph node metastasis could be predicted by evaluation of macrophage infiltration and hsp70 expression in superficial carcinoma of the esophagus.
Neoplasms
Lysosomal Rerouting of Hsp70 Trafficking as a Potential Immune Activating Tool for Targeting Melanoma.
Neoplasms
m5C Methylation Guides Systemic Transport of Messenger RNA over Graft Junctions in Plants.
Neoplasms
Macrocycles that inhibit the binding between heat shock protein 90 and TPR-containing proteins.
Neoplasms
Macrocyclic inhibitors of hsp90.
Neoplasms
Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended biomarker activity.
Neoplasms
Macrophage Inflammatory Protein Derivative ECI301 Enhances the Alarmin-Associated Abscopal Benefits of Tumor Radiotherapy.
Neoplasms
Macrophages orchestrate the immune response to tumor cell death.
Neoplasms
Magnetic nanoparticle-mediated hyperthermia therapy induces tumour growth inhibition by apoptosis and Hsp90/AKT modulation.
Neoplasms
Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.
Neoplasms
Magnetic thermoablation stimuli alter BCL2 and FGF-R1 but not HSP70 expression profiles in BT474 breast tumors.
Neoplasms
Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity.
Neoplasms
Making HSP90 Inhibitors Great Again? Unite for Better Cancer Immunotherapy.
Neoplasms
Mapping of the genes for human endoplasmic reticular heat shock protein gp96/grp94.
Neoplasms
Marchantin M Induces Apoptosis of Prostate Cancer Cells Through Endoplasmic Reticulum Stress.
Neoplasms
Marked induction of HSP47, a collagen-binding stress protein, during solid tumor formation of ascitic Sarcoma 180 in vivo.
Neoplasms
Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage.
Neoplasms
Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue.
Neoplasms
Maximizing the Therapeutic Potential of Hsp90 Inhibitors.
Neoplasms
MDM2 chaperones the p53 tumor suppressor.
Neoplasms
Measurement and mathematical modeling of thermally induced injury and heat shock protein expression kinetics in normal and cancerous prostate cells.
Neoplasms
Measurement and modification of the expression level of the chaperone protein and signaling regulator GRP78/BiP in mammalian cells.
Neoplasms
Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/neu expression in mice using Zr-DFO-trastuzumab.
Neoplasms
Mechanism study of peptide GMBP1 and its receptor GRP78 in modulating gastric cancer MDR by iTRAQ-based proteomic analysis.
Neoplasms
Mechanism underlying berberine's effects on HSP70/TNF? under heat stress: Correlation with the TATA boxes.
Neoplasms
Mechanism underlying the development of myeloproliferative neoplasms through mutant calreticulin.
Neoplasms
Mechanisms of apoptosis by the tumor suppressor Par-4.
Neoplasms
Mechanisms of decreased Vitamin D 1alpha-hydroxylase activity in prostate cancer cells.
Neoplasms
Mechanisms of disease: the role of heat-shock protein 90 in genitourinary malignancy.
Neoplasms
Mechanisms of endogenous MHC class II presentation by tumor cells.
Neoplasms
Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges.
Neoplasms
Mechanisms of Thrombocytopenia During Septic Shock: A Multiplex Cluster Analysis of Endogenous Sepsis Mediators.
Neoplasms
Mechanistic Asymmetry in Hsp90 Dimers.
Neoplasms
Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma.
Neoplasms
Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery.
Neoplasms
Mechanistic studies of Sansalvamide A-amide: an allosteric modulator of Hsp90.
Neoplasms
Mechanistic studies on Hsp90 inhibition by ansamycin derivatives.
Neoplasms
Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion.
Neoplasms
Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein.
Neoplasms
Medium-Chain Triglycerides Attenuate Liver Injury in Lipopolysaccharide-Challenged Pigs by Inhibiting Necroptotic and Inflammatory Signaling Pathways.
Neoplasms
Medium-Throughput Detection of Hsp90/Cdc37 Protein-Protein Interaction Inhibitors Using a Split Renilla Luciferase-Based Assay.
Neoplasms
Megakaryocytes mediate hyperglycemia-induced tumor metastasis.
Neoplasms
Melanoma and the Unfolded Protein Response.
Neoplasms
Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release.
Neoplasms
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms.
Neoplasms
Membrane heat shock protein 70: a theranostic target for cancer therapy.
Neoplasms
Membrane Hsp70-supported cell-to-cell connections via tunneling nanotubes revealed by live-cell STED nanoscopy.
Neoplasms
Membrane phospholipids, EML4-ALK, and Hsp90 as novel targets in lung cancer treatment.
Neoplasms
Membrane-anchored heat-shock protein 70 (Hsp70) in cancer.
Neoplasms
Membrane-bound heat shock protein 70 (Hsp70) in acute myeloid leukemia: a tumor specific recognition structure for the cytolytic activity of autologous NK cells.
Neoplasms
Membrane-bound HSP70-engineered myeloma cell-derived exosomes stimulate more efficient CD8(+) CTL- and NK-mediated antitumor immunity than exosomes released from heat-shocked tumor cells expressing cytoplasmic HSP70.
Neoplasms
Message in a bottle: role of the 70-kDa heat shock protein family in anti-tumor immunity.
Neoplasms
Metabolic markers and HSP60 in chemonaive serous solid ovarian cancer versus ascites.
Neoplasms
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells.
Neoplasms
Metabolite elucidation of the Hsp90 inhibitor SNX-2112 using ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS).
Neoplasms
Metastasis and the Tumor Microenvironment: A Joint Metastasis Research Society-AACR Conference - Research on Metastasis: Part 2.
Neoplasms
Methionine to isothreonine conversion as a source of false discovery identifications of genetically encoded variants in proteogenomics.
Neoplasms
Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development.
Neoplasms
Methylglyoxal and Small Heat Shock Proteins.
Neoplasms
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.
Neoplasms
MHC-class-I expression in human breast cancer correlates with nuclear localization of the 90 kDa heat-shock-protein.
Neoplasms
Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.
Neoplasms
MicroRNA overexpression increases cortical neuronal vulnerability to injury.
Neoplasms
MicroRNA-361-Mediated Inhibition of HSP90 Expression and EMT in Cervical Cancer Is Counteracted by Oncogenic lncRNA NEAT1.
Neoplasms
MicroRNA-495-3p inhibits multidrug resistance by modulating autophagy through GRP78/mTOR axis in gastric cancer.
Neoplasms
MicroRNA216b mediated downregulation of HSP27/STAT3/AKT signaling is critically involved in lambertianic acid induced apoptosis in human cervical cancers.
Neoplasms
MicroRNAs and Heat Shock Proteins in Breast Cancer Biology.
Neoplasms
Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines.
Neoplasms
Milan PM1 Induces Adverse Effects on Mice Lungs and Cardiovascular System.
Neoplasms
Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.
Neoplasms
Mild hypothermia facilitates the expression of cold-inducible RNA-binding protein and heat shock protein 70.1 in mouse brain.
Neoplasms
Mild Magnetic Hyperthermia-Activated Innate Immunity for Liver Cancer Therapy.
Neoplasms
Mimetic Heat Shock Protein Mediated Immune Process to Enhance Cancer Immunotherapy.
Neoplasms
Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer.
Neoplasms
MiR-181a Inhibits Cervical Cancer Development Via Downregulating GRP78.
Neoplasms
miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer.
Neoplasms
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.
Neoplasms
miR-485-5p/HSP90 axis blocks Akt1 phosphorylation to suppress osteosarcoma cell proliferation and migration via PI3K/AKT pathway.
Neoplasms
miR-541-3p enhances the radiosensitivity of prostate cancer cells by inhibiting HSP27 expression and downregulating ?-catenin.
Neoplasms
miR?495 enhances the efficacy of radiotherapy by targeting GRP78 to regulate EMT in nasopharyngeal carcinoma cells.
Neoplasms
miRNA mediated up-regulation of cochaperone p23 acts as an anti-apoptotic factor in childhood acute lymphoblastic leukemia.
Neoplasms
Mitochondria chaperone GRP75 moonlighting as a cell cycle controller to derail endocytosis provides an opportunity for nanomicrosphere intracellular delivery.
Neoplasms
Mitochondria-targeting NO gas nanogenerator for augmenting mild photothermal therapy in the NIR-II biowindow.
Neoplasms
Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating mitochondrial permeability transition pore opening.
Neoplasms
Mitochondrial chaperone, TRAP1 as a potential pharmacological target to combat cancer metabolism.
Neoplasms
Mitochondrial chaperone, TRAP1 modulates mitochondrial dynamics and promotes tumor metastasis.
Neoplasms
Mitochondrial chaperones in cancer: from molecular biology to clinical diagnostics.
Neoplasms
Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone.
Neoplasms
Mitochondrial heat shock protein mortalin as potential target for therapies based on oxidative stress.
Neoplasms
Mitochondrial Heat Shock Protein-90 Modulates Vascular Smooth Muscle Cell Survival and the Vascular Injury Response in Vivo.
Neoplasms
Mitochondrial heat shock protein-guided photodynamic therapy.
Neoplasms
Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
Neoplasms
Mitochondrial HSP90s and tumor cell metabolism.
Neoplasms
Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma.
Neoplasms
Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells.
Neoplasms
Mitochondrial-targeted Hsp90 C-terminal inhibitors manifest anti-proliferative activity.
Neoplasms
Mitofusin-2 regulates inflammation-mediated mouse neuroblastoma N2a cells dysfunction and endoplasmic reticulum stress via the Yap-Hippo pathway.
Neoplasms
Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis.
Neoplasms
Mitogen-activated protein kinase-activated protein kinase 2 in neuroinflammation, heat shock protein 27 phosphorylation, and cell cycle: role and targeting.
Neoplasms
Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX.
Neoplasms
Modeling and docking studies on novel mutants (K71L and T204V) of the ATPase domain of human heat shock 70 kDa protein 1.
Neoplasms
Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer.
Neoplasms
Modified biphenyl Hsp90 C-terminal inhibitors for the treatment of cancer.
Neoplasms
Modulating Heat Shock Proteins 70 and 90 Expression by Low Power Laser Irradiation (635nm and 780nm) in Jurkat E6.1 T-lymphocyte Leukemia Cell Line.
Neoplasms
Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001.
Neoplasms
Modulation of Human Hsp90? Conformational Dynamics by Allosteric Ligand Interaction at the C-Terminal Domain.
Neoplasms
Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition.
Neoplasms
Modulation of Mitochondrial Metabolic Reprogramming and Oxidative Stress to Overcome Chemoresistance in Cancer.
Neoplasms
Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228.
Neoplasms
Modulation of the unfolded protein response by GRP78 in prostate cancer.
Neoplasms
Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78.
Neoplasms
Modulatory effects of curcumin on heat shock proteins in cancer: A promising therapeutic approach.
Neoplasms
Modulatory effects of mycobacterial heat-shock protein 70 in DNA vaccination against lymphoma.
Neoplasms
Molecular aberrations in the MHC class I-restricted pathway for antigen presentation in methylcholanthrene sarcomas from nude mice: discrepancies between MHC mRNA and surface protein.
Neoplasms
Molecular and cellular basis for the anti-proliferative effects of the HDAC inhibitor LAQ824.
Neoplasms
Molecular and cellular requirements for enhanced antigen cross-presentation to CD8 cytotoxic T lymphocytes.
Neoplasms
Molecular and Clinical Characterization of CCT2 Expression and Prognosis via Large-Scale Transcriptome Profile of Breast Cancer.
Neoplasms
Molecular and functional crosstalk between extracellular Hsp90 and ephrin A1 signaling.
Neoplasms
Molecular basis for the actions of Hsp90 inhibitors and cancer therapy.
Neoplasms
Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1.
Neoplasms
Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
Neoplasms
Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target.
Neoplasms
Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer.
Neoplasms
Molecular chaperone Hsp90 as a target for oxidant-based anticancer therapies.
Neoplasms
Molecular chaperone Hsp90 is a therapeutic target for noroviruses.
Neoplasms
Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.
Neoplasms
Molecular chaperone therapy- the future in cancer.
Neoplasms
Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis.
Neoplasms
Molecular Chaperones and Thyroid Cancer.
Neoplasms
Molecular chaperones as regulators of cell death.
Neoplasms
Molecular Chaperones in Cancer Stem Cells: Determinants of Stemness and Potential Targets for Antitumor Therapy.
Neoplasms
Molecular chaperones stimulate bone resorption.
Neoplasms
Molecular characterization of hsp90 isoforms in colorectal cancer cells and its association with tumour progression.
Neoplasms
Molecular characterization of macbecin as an Hsp90 inhibitor.
Neoplasms
Molecular cochaperones: tumor growth and cancer treatment.
Neoplasms
Molecular design of anticancer drug leads based on three-dimensional quantitative structure-activity relationship.
Neoplasms
Molecular docking and molecular dynamics studies reveal structural basis of inhibition and selectivity of inhibitors EGCG and OSU-03012 toward glucose regulated protein-78 (GRP78) overexpressed in glioblastoma.
Neoplasms
Molecular docking and pharmacophore studies of heterocyclic compounds as Heat shock protein 90 (Hsp90) Inhibitors.
Neoplasms
Molecular docking simulation analysis of the interaction of dietary flavonols with heat shock protein 90.
Neoplasms
Molecular docking study, synthesis and biological evaluation of Schiff bases as Hsp90 inhibitors.
Neoplasms
Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects.
Neoplasms
Molecular markers for novel therapies in neuroendocrine (carcinoid) tumors.
Neoplasms
Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells.
Neoplasms
Molecular mechanism of kidney injury of mice caused by exposure to titanium dioxide nanoparticles.
Neoplasms
Molecular mechanisms of anti-tumor properties of P276-00 in head and neck squamous cell carcinoma.
Neoplasms
Molecular Pathways: GLI1-Induced Drug Glucuronidation in Resistant Cancer Cells.
Neoplasms
Molecular pathways: targeting hsp90--who benefits and who does not.
Neoplasms
Molecular sequelae of proteasome inhibition in human multiple myeloma cells.
Neoplasms
Molecular signature of response and potential pathways related to resistance to the HSP90 inhibitor, 17AAG, in breast cancer.
Neoplasms
Molecular Targeting-Mediated Mild-Temperature Photothermal Therapy with a Smart Albumin-Based Nanodrug.
Neoplasms
Molecular Targets Implicated in the Antiparasitic and Anti-Inflammatory Activity of the Phytochemical Curcumin in Trichomoniasis.
Neoplasms
Molecular-biological analysis of acute lung injury (ALI) induced by heat exposure and/or intravenous administration of oleic acid.
Neoplasms
Molecularly engineered carrier-free co-delivery nanoassembly for self-sensitized photothermal cancer therapy.
Neoplasms
Molecularly targeted therapies in multiple myeloma.
Neoplasms
Monitoring HSP70 exosomes in cancer patients' follow up: a clinical prospective pilot study.
Neoplasms
Monitoring of Heat Shock Response and Phenotypic Changes in Hepatocellular Carcinoma After Heat Treatment.
Neoplasms
Monitoring therapeutic response of human ovarian cancer to 17-DMAG by noninvasive PET imaging with (64)Cu-DOTA-trastuzumab.
Neoplasms
Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis.
Neoplasms
Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits.
Neoplasms
Monoclonal Antibody against Cell Surface GRP78 as a Novel Agent in Suppressing PI3K/AKT Signaling, Tumor Growth and Metastasis.
Neoplasms
Monoclonal antibody to novel cell surface epitope on Hsc70 promotes morphogenesis of bile ducts in newborn rat liver.
Neoplasms
More efficient induction of HLA-A*0201-restricted and carcinoembryonic antigen (CEA)-specific CTL response by immunization with exosomes prepared from heat-stressed CEA-positive tumor cells.
Neoplasms
Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells.
Neoplasms
Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability.
Neoplasms
Mortalin antibody-conjugated quantum dot transfer from human mesenchymal stromal cells to breast cancer cells requires cell-cell interaction.
Neoplasms
Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-RafV600E melanoma cells.
Neoplasms
Mortalin expression in pancreatic cancer and its clinical and prognostic significance.
Neoplasms
Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates.
Neoplasms
Mortalin inhibitors sensitize K562 leukemia cells to complement-dependent cytotoxicity.
Neoplasms
Mortalin is a distinct bio-marker and prognostic factor in serous ovarian carcinoma.
Neoplasms
Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival.
Neoplasms
Mortalin maintains breast cancer stem cells stemness via activation of Wnt/GSK3?/?-catenin signaling pathway.
Neoplasms
Mortalin peptides exert antitumor activities and act as adjuvants to antibody-mediated complement-dependent cytotoxicity.
Neoplasms
Mortalin promotes breast cancer malignancy.
Neoplasms
Mortalin promotes cell proliferation and epithelial mesenchymal transition of intrahepatic cholangiocarcinoma cells in vitro.
Neoplasms
Mortalin sensitizes human cancer cells to MKT-077-induced senescence.
Neoplasms
Mortalin stabilizes CD151-depedent tetraspanin-enriched microdomains and implicates in the progression of hepatocellular carcinoma.
Neoplasms
Mortalin, apoptosis, and neurodegeneration.
Neoplasms
Mortalin-based cytoplasmic sequestration of p53 in a nonmammalian cancer model.
Neoplasms
Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy.
Neoplasms
Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability.
Neoplasms
Mortalin - a multipotent chaperone regulating cellular processes ranging from viral infection to neurodegeneration.
Neoplasms
Mortaparib, a novel dual inhibitor of mortalin and PARP1, is a potential drug candidate for ovarian and cervical cancers.
Neoplasms
Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.
Neoplasms
MT-4 suppresses resistant ovarian cancer growth through targeting tubulin and HSP27.
Neoplasms
mTOR Inhibition Potentiates HSP90 Inhibitor Activity via Cessation of Heat Shock Protein Synthesis.
Neoplasms
Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.
Neoplasms
Multi-faceted role of HSP40 in cancer.
Neoplasms
Multi-level ecotoxicological effects of imidacloprid on earthworm (Eisenia fetida).
Neoplasms
Multi-panel assay of serum autoantibodies in colorectal cancer.
Neoplasms
Multicenter Phase II Trial of the Heat Shock Protein 90 Inhibitor, Retaspimycin Hydrochloride (IPI-504), in Patients With Castration-resistant Prostate Cancer.
Neoplasms
Multiclass comparative virtual screening to identify novel Hsp90 inhibitors: a therapeutic breast cancer drug target.
Neoplasms
Multidimensional degradomics identifies systemic autoantigens and intracellular matrix proteins as novel gelatinase B/MMP-9 substrates.
Neoplasms
Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signaling.
Neoplasms
Multifocal angiostatic therapy: an update.
Neoplasms
Multifunctional low-temperature photothermal nanodrug with in vivo clearance, ROS-Scavenging and anti-inflammatory abilities.
Neoplasms
Multifunctional Magnetic Nanoplatform Eliminates Cancer Stem Cells via Inhibiting the Secretion of Extracellular Heat Shock Protein 90.
Neoplasms
Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells.
Neoplasms
Multifunctional TPP-PEG-biotin self-assembled nanoparticle drug delivery-based combination therapeutic approach for co-targeting of GRP78 and lysosome.
Neoplasms
Multiple Kinase Pathways Involved in the Different De Novo Sensitivity of Pancreatic Cancer Cell Lines to 17-AAG.
Neoplasms
Multiple p53 protein isoforms and formation of oligomeric complexes with heat shock proteins Hsp70 and Hsp90 in the human mammary tumor, T47D, cell line.
Neoplasms
Multiplex Cytokine Profiling Identifies Interleukin-27 as a Novel Biomarker for Neonatal Early Onset Sepsis.
Neoplasms
Multiplex H. pylori serology and risk of gastric cardia and non-cardia adenocarcinomas.
Neoplasms
Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40.
Neoplasms
Muscle Antioxidant Activity and Meat Quality Are Altered by Supplementation of Astaxanthin in Broilers Exposed to High Temperature.
Neoplasms
Muscle endurance in elderly nursing home residents is related to fatigue perception, mobility, and circulating tumor necrosis factor-alpha, interleukin-6, and heat shock protein 70.
Neoplasms
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity.
Neoplasms
Mutations Y493G and K546D in human HSP90 disrupt binding of celastrol and reduce interaction with Cdc37.
Neoplasms
Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth.
Neoplasms
Mycobacterial 65-kilodalton heat shock protein induces tumor necrosis factor alpha and interleukin 6, reactive nitrogen intermediates, and toxoplasmastatic activity in murine peritoneal macrophages.
Neoplasms
N,N'-dinitrosopiperazine--mediated heat-shock protein 70-2 expression is involved in metastasis of nasopharyngeal carcinoma.
Neoplasms
N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-? induced PD-L1 expression.
Neoplasms
N-Formyl-3,4-methylenedioxy-benzylidene-gamma-butyrolaetam, KNK437 induces caspase-3 activation through inhibition of mTORC1 activity in Cos-1 cells.
Neoplasms
N-terminal and C-terminal modulation of Hsp90 produce dissimilar phenotypes.
Neoplasms
NaCN-induced chemical hypoxia is associated with altered gene expression.
Neoplasms
NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones.
Neoplasms
Nanobubble Ultrasound Contrast Agents for Enhanced Delivery of Thermal Sensitizer to Tumors Undergoing Radiofrequency Ablation.
Neoplasms
Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer.
Neoplasms
Nanofitins targeting heat shock protein 110: An innovative immunotherapeutic modality in cancer.
Neoplasms
Nanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78.
Neoplasms
Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors.
Neoplasms
Natural compounds as potential Hsp90 inhibitors for breast cancer-Pharmacophore guided molecular modelling studies.
Neoplasms
Natural heat shock protein 90 inhibitors in cancer and inflammation.
Neoplasms
Natural iminosugar (+)-lentiginosine inhibits ATPase and chaperone activity of hsp90.
Neoplasms
Natural Infection with Rabies Virus: A Histopathological and Immunohistochemical Study of Human Brains.
Neoplasms
Natural killer cells play a key role in the antitumor immunity generated by chaperone-rich cell lysate vaccination.
Neoplasms
Natural product inhibitors of Hsp90: potential leads for drug discovery.
Neoplasms
Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?
Neoplasms
Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis.
Neoplasms
Natural Products in Structure-Assisted Design of Molecular Cancer Therapeutics.
Neoplasms
Natural Withanolides in the Treatment of Chronic Diseases.
Neoplasms
NECA derivatives exploit the paralog-specific properties of the Site 3 side pocket of Grp94, the ER Hsp90.
Neoplasms
Neoadjuvant and adjuvant strategies in renal cell carcinoma: more questions than answers.
Neoplasms
Nephro-toxic effects of intraperitoneally injected EGCG in diabetic mice: involvement of oxidative stress, inflammation and apoptosis.
Neoplasms
Network pharmacology-based and clinically relevant prediction of the active ingredients and potential targets of Chinese herbs in metastatic breast cancer patients.
Neoplasms
Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98.
Neoplasms
New aspects of the hormone and cytokine response to training.
Neoplasms
New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.
Neoplasms
New geldanamycin analogs from Streptomyces hygroscopicus.
Neoplasms
New heat shock protein (Hsp90) inhibitors, designed by pharmacophore modeling and virtual Screening: Synthesis, Biological evaluation and molecular dynamics studies.
Neoplasms
New insights into molecular chaperone TRAP1 as a feasible target for future cancer treatments.
Neoplasms
New insights into TRAP1 pathway.
Neoplasms
New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment.
Neoplasms
New role of endoplasmic reticulum chaperones in regulating metaplasia during tumorigenesis.
Neoplasms
Nickel and Oxidative stress: Cell Signaling Mechanisms and Protective Role of Vitamin C.
Neoplasms
NIR-activated self-sensitized polymeric micelles for enhanced cancer chemo-photothermal therapy.
Neoplasms
NIR-controlled HSP90 inhibitor release from hollow mesoporous nanocarbon for synergistic tumor photothermal therapy guided by photoacoustic imaging.
Neoplasms
NIR-II Absorbing Semiconducting Polymer-Triggered Gene-Directed Enzyme Prodrug Therapy for Cancer Treatment.
Neoplasms
NIR-II Excitation Phototheranostic Nanomedicine for Fluorescence/Photoacoustic Tumor Imaging and Targeted Photothermal-Photonic Thermodynamic Therapy.
Neoplasms
Nitration of Hsp90 on Tyrosine 33 Regulates Mitochondrial Metabolism.
Neoplasms
Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression.
Neoplasms
NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation.
Neoplasms
NMS-E973, a novel synthetic inhibitor of Hsp90 with activity against multiple models of drug resistance to targeted agents, including intracranial metastases.
Neoplasms
Non-Benzoquinone Geldanamycin Analog, WK-88-1, Induces Apoptosis in Human Breast Cancer Cell Lines.
Neoplasms
Non-HLA gene polymorphisms and the outcome of allogeneic hemato-poietic stem cell transplantation.
Neoplasms
Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model.
Neoplasms
Non-invasive PET imaging of EGFR degradation induced by a heat shock protein 90 inhibitor.
Neoplasms
Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin.
Neoplasms
Noncovalent association with stress protein facilitates cross-priming of CD8+ T cells to tumor cell antigens by dendritic cells.
Neoplasms
Nonsteroidal Anti-inflammatory Drugs Sensitize CD44-Overexpressing Cancer Cells to Hsp90 Inhibitor Through Autophagy Activation.
Neoplasms
Nonviral nanoscale-based delivery of antisense oligonucleotides targeted to hypoxia-inducible factor 1 alpha enhances the efficacy of chemotherapy in drug-resistant tumor.
Neoplasms
Novel 1,6-naphthyridin-2(1H)-ones as potential anticancer agents targeting Hsp90.
Neoplasms
Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial.
Neoplasms
Novel antitumor and neuroprotective substances discovered by characteristic screenings based on specific molecular targets.
Neoplasms
Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells.
Neoplasms
Novel C-Terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents.
Neoplasms
Novel findings in gene expression detected in human osteosarcoma by cDNA microarray.
Neoplasms
Novel Heat Shock Protein 90 Inhibitors Suppress P-Glycoprotein Activity and Overcome Multidrug Resistance in Cancer Cells.
Neoplasms
Novel Hsp90 Inhibitor C086 Potently Inhibits Non-Small Cell Lung Cancer Cells As A Single Agent Or In Combination With Gefitinib.
Neoplasms
Novel Hsp90 inhibitor FW-04-806 displays potent antitumor effects in HER2-positive breast cancer cells as a single agent or in combination with lapatinib.
Neoplasms
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells.
Neoplasms
Novel HSP90 inhibitor NVP-HSP990 targets cell cycle regulators to ablate Olig2-positive glioma tumor initiating cells.
Neoplasms
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor.
Neoplasms
Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction.
Neoplasms
Novel mechanism of apoptosis resistance in cancer mediated by extracellular PAR-4.
Neoplasms
Novel Miniaturized Drug Conjugate Leverages HSP90-driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors.
Neoplasms
Novel molecular mechanism of cellular transformation by a mutant molecular chaperone in myeloproliferative neoplasms.
Neoplasms
Novel nontoxic heat shock protein 90 inhibitors having selective antiproliferative effect.
Neoplasms
Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53.
Neoplasms
Novel prediction of anticancer drug chemosensitivity in cancer cell lines: evidence of moderation by microRNA expressions.
Neoplasms
Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2low ATL and various cancer cells.
Neoplasms
Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolism.
Neoplasms
Novel ruthenium(II) triazine complex [Ru(bdpta)(tpy)]2+ co-targeting drug resistant GRP78 and subcellular organelles in cancer stem cells.
Neoplasms
Novel serum markers HSP60, CHI3L1, and IGFBP-2 in metastatic colorectal cancer.
Neoplasms
Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling.
Neoplasms
Novel targeted nuclear imaging agent for gastric cancer diagnosis: glucose-regulated protein 78 binding peptide-guided 111In-labeled polymeric micelles.
Neoplasms
Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors.
Neoplasms
Novel therapeutic targets for multiple myeloma.
Neoplasms
Novel treatment strategies for soft tissue sarcoma.
Neoplasms
Novel triazole ribonucleoside down-regulates heat shock protein 27 and induces potent anticancer activity on drug-resistant pancreatic cancer.
Neoplasms
Novobiocin analogs as potencial anticancer agents.
Neoplasms
Novobiocin analogues with second-generation noviose surrogates.
Neoplasms
Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.
Neoplasms
Nuclear Accumulation of Heat-shock Protein 90 Is Associated with Poor Survival and Metastasis in Patients with Non-small Cell Lung Cancer.
Neoplasms
Nuclear export of proteins and drug resistance in cancer.
Neoplasms
Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT).
Neoplasms
Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma.
Neoplasms
Nucleoside-Lipid-Based Nanoparticles for Phenazine Delivery: A New Therapeutic Strategy to Disrupt Hsp27-eIF4E Interaction in Castration Resistant Prostate Cancer.
Neoplasms
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
Neoplasms
NZ28-induced inhibition of HSF1, SP1 and NF-?B triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells.
Neoplasms
Ochratoxin A upregulates biomarkers associated with hypoxia and transformation in human kidney cells.
Neoplasms
OGX-427 inhibits tumor progression and enhances gemcitabine chemotherapy in pancreatic cancer.
Neoplasms
Okicamelliaside targets the N-terminal chaperone pocket of HSP90 disrupts the chaperone protein interaction of HSP90-CDC37 and exerts antitumor activity.
Neoplasms
Old and New Approaches to Target the Hsp90 Chaperone.
Neoplasms
Oncogenic acidic nuclear phosphoproteins ANP32C/D are novel clients of heat shock protein 90.
Neoplasms
Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells.
Neoplasms
Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth.
Neoplasms
Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas.
Neoplasms
Oncogenic ras results in increased cell kill due to defective thermoprotection in lung cancer cells.
Neoplasms
Oncogenic role of mortalin contributes to ovarian tumorigenesis by activating the MAPK-ERK pathway.
Neoplasms
Optical and radioiodinated tethered hsp90 inhibitors reveal selective internalization of ectopic hsp90 in malignant breast tumor cells.
Neoplasms
Optical Imaging of Treatment-Related Tumor Cell Death Using a Heat Shock Protein-90 Alkylator.
Neoplasms
Optimization and biological evaluation of celastrol derivatives as Hsp90-Cdc37 interaction disruptors with improved druglike properties.
Neoplasms
Optimization of expression and purification of human mortalin (Hsp70): Folding/unfolding analysis.
Neoplasms
Optimized HSP90 mediated fluorescent probes for cancer-specific bioimaging.
Neoplasms
Optimizing heat shock protein expression induced by prostate cancer laser therapy through predictive computational models.
Neoplasms
Oral administration of heat-killed Lactobacillus brevis SBC8803 ameliorates alcoholic liver disease in ethanol-containing diet-fed C57BL/6N mice.
Neoplasms
Orally active purine-based inhibitors of the heat shock protein 90.
Neoplasms
Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment.
Neoplasms
Oroxin A inhibits breast cancer cell growth by inducing robust endoplasmic reticulum stress and senescence.
Neoplasms
Osteoarthritis-related biomarkers profile in chronic anterior cruciate ligament injured knee.
Neoplasms
Osteopontin increases breast cancer cell sensitivity to specific signaling pathway inhibitors in preclinical models.
Neoplasms
Ovarian Serous Carcinoma With a Novel HSP90AB1 Mutation in a Patient With Synchronous Primary Fallopian Tube Serous Carcinoma.
Neoplasms
Over-expression of heat shock protein 70 in mice is associated with growth retardation, tumor formation, and early death.
Neoplasms
Over-expression of heat shock proteins in carcinogenic endometrium.
Neoplasms
Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer.
Neoplasms
Overcoming drug-tolerant cancer cell subpopulations showing AXL activation and epithelial-mesenchymal transition is critical in conquering ALK-positive lung cancer.
Neoplasms
Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules.
Neoplasms
Overcoming immune tolerance to cancer by heat shock protein vaccines.
Neoplasms
Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy.
Neoplasms
Overcoming the hypoxia-induced drug resistance in liver tumor by the concurrent use of apigenin and paclitaxel.
Neoplasms
Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-?/Smad2/3 signaling.
Neoplasms
Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significance.
Neoplasms
Overexpression of glucose-regulated protein 78 in colon cancer.
Neoplasms
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
Neoplasms
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Neoplasms
Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors.
Neoplasms
Overexpression of heat shock protein (hsp) 70 associated with abnormal p53 expression in cancer of the pancreas.
Neoplasms
Overexpression of heat shock protein 27 (HSP-27) is associated with bad prognosis in oral squamous cell carcinoma.
Neoplasms
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.
Neoplasms
Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients.
Neoplasms
Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro.
Neoplasms
Overexpression of major heat shock protein hsp70 inhibits tumor necrosis factor-induced activation of phospholipase A2.
Neoplasms
Overexpression of molecular chaperons GRP78 and GRP94 in CD44(hi)/CD24(lo) breast cancer stem cells.
Neoplasms
Overexpression of Mortalin in hepatocellular carcinoma and its relationship with angiogenesis and epithelial to mesenchymal transition.
Neoplasms
Overexpression of PI3K-p110? in the progression of uterine cervical neoplasia and its correlation with pAkt and DJ-1.
Neoplasms
Overexpression of ras is an independent prognostic factor in colorectal adenocarcinoma.
Neoplasms
Overexpression of ST6GalNAcV, a ganglioside-specific alpha2,6-sialyltransferase, inhibits glioma growth in vivo.
Neoplasms
Overexpression of the anti-apoptotic protein BAG3 in human choroidal melanoma: A case report.
Neoplasms
Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions.
Neoplasms
Overexpression of the mitochondrial chaperone tumor necrosis factor receptor-associated protein 1 is associated with the poor prognosis of patients with colorectal cancer.
Neoplasms
Overexpression of tumor necrosis factor receptor-associated protein 1 (TRAP1), leads to mitochondrial aberrations in mouse fibroblast NIH/3T3 cells.
Neoplasms
Overview: translating Hsp90 biology into Hsp90 drugs.
Neoplasms
Oxidant stress evoked damage in rat hepatocyte leading to triggered nitric oxide synthase (NOS) levels on long term consumption of aspartame.
Neoplasms
Ozone oxidative preconditioning is mediated by A1 adenosine receptors in a rat model of liver ischemia/ reperfusion.
Neoplasms
p300 mediates muscle wasting in Lewis lung carcinoma.
Neoplasms
P4HB: A novel diagnostic and prognostic biomarker for bladder carcinoma.
Neoplasms
p53 expression in brain after middle cerebral artery occlusion in the rat.
Neoplasms
p53 independent radio-sensitization of human lymphoblastoid cell lines by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
Neoplasms
p53 status-dependent sensitization of human tumour cells to hyperthermia by plant flavonol.
Neoplasms
P53-dependent radiosensitizing effects of Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin on human oral squamous cell carcinoma cell lines.
Neoplasms
Paclitaxel inhibits expression of heat shock protein 27 in ovarian and uterine cancer cells.
Neoplasms
Paclitaxel-doxorubicin sequence is more effective in breast cancer cells with heat shock protein 27 overexpression.
Neoplasms
Paeonol protects against testicular ischaemia-reperfusion injury in rats through inhibition of oxidative stress and inflammation.
Neoplasms
Pancastatin A and B Have Selective Cytotoxicity on Glucose-Deprived PANC-1 Human Pancreatic Cancer Cells.
Neoplasms
Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.
Neoplasms
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
Neoplasms
Part I of GANNET53: A European Multicenter Phase I/II Trial of the Hsp90 Inhibitor Ganetespib Combined With Weekly Paclitaxel in Women With High-Grade, Platinum-Resistant Epithelial Ovarian Cancer-A Study of the GANNET53 Consortium.
Neoplasms
Particulate cytoplasmic structures with high concentration of ubiquitin-proteasome accumulate in myeloid neoplasms.
Neoplasms
Past, present, and emerging roles of mitochondrial heat shock protein TRAP1 in the metabolism and regulation of cancer stem cells.
Neoplasms
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage.
Neoplasms
Pathological Mechanism of Photodynamic Therapy and Photothermal Therapy Based on Nanoparticles.
Neoplasms
Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracilbased chemotherapy.
Neoplasms
Patterns of GRP78 and MTJ1 expression in primary cutaneous malignant melanoma.
Neoplasms
Penicisulfuranol A, a novel C-terminal inhibitor disrupting molecular chaperone function of Hsp90 independent of ATP binding domain.
Neoplasms
Peptide-binding heat shock protein GRP78 protects cardiomyocytes from hypoxia-induced apoptosis.
Neoplasms
Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy.
Neoplasms
Perfluorooctyl bromide & indocyanine green co-loaded nanoliposomes for enhanced multimodal imaging-guided phototherapy.
Neoplasms
Perinecrotic hypoxia contributes to ischemia/reperfusion-accelerated outgrowth of colorectal micrometastases.
Neoplasms
Peripheral blood mononuclear cell responses to heat shock proteins in patients undergoing stem cell transplantation.
Neoplasms
Peripheral blood mRNA expressions of stress biomarkers in manic episode and subsequent remission.
Neoplasms
Peroxiredoxin 1 stimulates secretion of proinflammatory cytokines by binding to TLR4.
Neoplasms
Perturbation of HSP Network in MCF-7 Breast Cancer Cell Line Triggers Inducible HSP70 Expression and Leads to Tumor Suppression.
Neoplasms
PET imaging of Hsp90 expression in pancreatic cancer using a new 64Cu-labeled dimeric Sansalvamide A decapeptide.
Neoplasms
PFT-alpha inhibits antibody-induced activation of p53 and pro-apoptotic signaling in 1-LN prostate cancer cells.
Neoplasms
PGK1-coupled HSP90 stabilizes GSK3? expression to regulate the stemness of breast cancer stem cells.
Neoplasms
pH-activated heat shock protein inhibition and radical generation enhanced NIR luminescence imaging-guided photothermal tumour ablation.
Neoplasms
pH-responsive Ag2S nanodots loaded with heat shock protein 70 inhibitor for photoacoustic imaging-guided photothermal cancer therapy.
Neoplasms
Phage display biopanning identifies the translation initiation and elongation factors (IF1?-3 and eIF-3) as components of Hsp70-peptide complexes in breast tumour cells.
Neoplasms
Phage display derived human monoclonal antibodies isolated by binding to the surface of live primary breast cancer cells recognize GRP78.
Neoplasms
Pharmaceutical Efficacy of Gypenoside LXXV on Non-Alcoholic Steatohepatitis (NASH).
Neoplasms
Pharmacogenomics in cancer drug discovery and development: inhibitors of the Hsp90 molecular chaperone.
Neoplasms
Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available heat shock protein 90 inhibitor in a human tumor xenograft mouse model.
Neoplasms
Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenografts.
Neoplasms
Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction.
Neoplasms
Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells.
Neoplasms
Pharmacological effectors of GRP78 chaperone in cancers.
Neoplasms
Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells.
Neoplasms
Pharmacological Inhibition of Hsp90 as a Novel Antitumor Strategy to Target Cytoarchitecture Through Extracellular Matrix Signaling.
Neoplasms
Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis.
Neoplasms
Pharmacophore-based virtual screening and docking studies on Hsp90 inhibitors.
Neoplasms
Pharmacoproteomics study of cetuximab in nasopharyngeal carcinoma.
Neoplasms
Phase 1 study of the HSP90 inhibitor onalespib in combination with AT7519, a pan-CDK inhibitor, in patients with advanced solid tumors.
Neoplasms
Phase I dose-escalation studies of SNX-5422, an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumours.
Neoplasms
Phase I dose-escalation study of the HSP90 inhibitor AUY922 in Japanese patients with advanced solid tumors.
Neoplasms
Phase I evaluation of STA-1474, a prodrug of the novel HSP90 inhibitor ganetespib, in dogs with spontaneous cancer.
Neoplasms
Phase I pharmacokinetic and pharmacodynamic study of 17-dimethylaminoethylamino-17-demethoxygeldanamycin, an inhibitor of heat-shock protein 90, in patients with advanced solid tumors.
Neoplasms
Phase I Pharmacokinetic and Pharmacodynamic Study of LAQ824, a Hydroxamate Histone Deacetylase Inhibitor with a Heat Shock Protein-90 Inhibitory Profile, in Patients with Advanced Solid Tumors.
Neoplasms
Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers.
Neoplasms
Phase I Study of BIIB028, a Selective Heat Shock Protein 90 Inhibitor, in Patients with Refractory Metastatic or Locally Advanced Solid Tumors.
Neoplasms
Phase I study of KW-2478, a novel Hsp90 inhibitor, in patients with B-cell malignancies.
Neoplasms
Phase I study of the heat shock protein 90 (Hsp90) inhibitor onalespib (AT13387) administered on a daily for 2 consecutive days per week dosing schedule in patients with advanced solid tumors.
Neoplasms
Phase I study of the heat shock protein 90 inhibitor alvespimycin (KOS-1022, 17-DMAG) administered intravenously twice weekly to patients with acute myeloid leukemia.
Neoplasms
Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies.
Neoplasms
Phase I trial of the HSP90 inhibitor PF-04929113 (SNX5422) in adult patients with recurrent, refractory hematologic malignancies.
Neoplasms
Phase I-II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo.
Neoplasms
Phase II trial of gemcitabine and tanespimycin (17AAG) in metastatic pancreatic cancer: a Mayo Clinic Phase II Consortium study.
Neoplasms
Phenotypic and functional effects of heat shock protein 90 inhibition on dendritic cell.
Neoplasms
Phenotypic identification of the redox dye methylene blue as an antagonist of heat shock response gene expression in metastatic melanoma cells.
Neoplasms
Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma.
Neoplasms
Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase.
Neoplasms
Phosphorylated Hsp27 activates ATM-dependent p53 signaling and mediates the resistance of MCF-7 cells to doxorubicin-induced apoptosis.
Neoplasms
Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer.
Neoplasms
Phosphorylation status of heat shock protein 27 plays a key role in gemcitabine-induced apoptosis of pancreatic cancer cells.
Neoplasms
Phosphorylation-Regulated Degradation of the Tumor-Suppressor Form of PED by Chaperone-Mediated Autophagy in Lung Cancer Cells.
Neoplasms
Photodynamic therapy-generated cancer vaccine elicits acute phase and hormonal response in treated mice.
Neoplasms
Photodynamic therapy-generated tumor cell lysates with CpG-oligodeoxynucleotide enhance immunotherapy efficacy in human papillomavirus 16 (E6/E7) immortalized tumor cells.
Neoplasms
Photodynamic therapy-induced cell surface expression and release of heat shock proteins: relevance for tumor response.
Neoplasms
Photodynamic therapy-mediated DC immunotherapy is highly effective for the inhibition of established solid tumors.
Neoplasms
Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy.
Neoplasms
Photothermal response of human and murine cancer cells to multiwalled carbon nanotubes after laser irradiation.
Neoplasms
Physical exercise induces excess hsp72 expression and delays the development of hyperalgesia and allodynia in painful diabetic neuropathy rats.
Neoplasms
Physical localization and order of genes in the class I region of the bovine MHC.
Neoplasms
Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone.
Neoplasms
PI3K-independent mTOR activation promotes lapatinib resistance and IAP expression that can be effectively reversed by mTOR and Hsp90 inhibition.
Neoplasms
Pifithrin-? incorporated in gold nanoparticle amplifies pro-apoptotic unfolded protein response cascades to potentiate synergistic glioblastoma therapy.
Neoplasms
Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.
Neoplasms
Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, accelerates gastric ulcer healing in rat.
Neoplasms
Placenta-derived gp96 as a multivalent prophylactic cancer vaccine.
Neoplasms
Plasma Heat Shock Protein 90 Alpha: A Valuable Predictor of Early Chemotherapy Effectiveness in Advanced Non-Small-Cell Lung Cancer.
Neoplasms
Plasma levels of heat shock protein 90 alpha associated with lung cancer development and treatment responses.
Neoplasms
Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.
Neoplasms
Plasminogen kringle 5 suppresses gastric cancer via regulating HIF-1? and GRP78.
Neoplasms
Platinum(iv) oxaliplatin-peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells.
Neoplasms
PLC?1-PKC? signaling-mediated Hsp90? plasma membrane translocation facilitates tumor metastasis.
Neoplasms
Plumbagin sensitizes breast cancer cells to tamoxifen-induced cell death through GRP78 inhibition and Bik upregulation.
Neoplasms
Polymerase chain reaction-aided analysis of gene expression in frozen tissue sections.
Neoplasms
Polymorphic analysis of MHClinked Heat Shock Protein 70 genes: Their susceptibility and prognostic implication in Kangri cancer cases of Kashmiri population.
Neoplasms
Polymorphism in the tumor necrosis factor-alpha promotor region and in the heat shock protein 70 genes associated with malignant tumors.
Neoplasms
Polymorphism of the stress protein HSP70-2 gene is associated with the susceptibility to the nasopharyngeal carcinoma.
Neoplasms
Polymorphism of the TNF-alpha, HSP70-2, and CD14 genes increases susceptibility to severe acute pancreatitis.
Neoplasms
Polymorphisms in the tumor necrosis factor-alpha gene at position -308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes.
Neoplasms
Polymorphisms in TNF and HSP-70 show a significant association with gastric cancer and duodenal ulcer.
Neoplasms
Polymorphisms of glucose-regulated protein 78 and clinical relevance of neuroblastoma: Risk and prognosis.
Neoplasms
Positive associations between upregulated levels of stress-induced phosphoprotein 1 and matrix metalloproteinase-9 in endometriosis/adenomyosis.
Neoplasms
Possible effects of early treatments of hsp90 inhibitors on preventing the evolution of drug resistance to other anti-cancer drugs.
Neoplasms
Post-transcriptional repair of a split heat shock protein 90 gene by mRNA trans-splicing.
Neoplasms
Post-translational modification of heat-shock protein 90: impact on chaperone function.
Neoplasms
Post-translational modifications of Hsp90 and their contributions to chaperone regulation.
Neoplasms
Post-treatment with a heat shock protein 90 inhibitor prevents chronic lung injury and pulmonary fibrosis, following acute exposure of mice to HCl.
Neoplasms
Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitors.
Neoplasms
Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo.
Neoplasms
Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression.
Neoplasms
Potent antitumor activity of HSP90 inhibitor AUY922 in adrenocortical carcinoma.
Neoplasms
Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells.
Neoplasms
Potent antitumor effect elicited by superantigen-linked tumor cells transduced with heat shock protein 70 gene.
Neoplasms
Potent Cytotoxic C-11 Modified Geldanamycin Analogues.
Neoplasms
Potent non-benzoquinone ansamycin heat shock protein 90 inhibitors from genetic engineering of Streptomyces hygroscopicus.
Neoplasms
Potential C-terminal-domain inhibitors of heat shock protein 90 derived from a C-terminal peptide helix.
Neoplasms
Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers.
Neoplasms
Potential Prognostic Value of Histone Deacetylase 6 and Acetylated Heat-Shock Protein 90 in Early-Stage Breast Cancer.
Neoplasms
Potentiation of chemotherapeutics by the Hsp90 antagonist geldanamycin requires a steady serum condition.
Neoplasms
PRDX2 in Myocyte Hypertrophy and Survival is Mediated by TLR4 in Acute Infarcted Myocardium.
Neoplasms
Pre-clinical safety evaluation of heat shock protein 65-MUC1 peptide fusion protein.
Neoplasms
Preclinical activity profile and therapeutic efficacy of the HSP90 inhibitor ganetespib in triple-negative breast cancer.
Neoplasms
Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer.
Neoplasms
Preclinical antitumor activity of SST0116CL1: a novel heat shock protein 90 inhibitor.
Neoplasms
Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers.
Neoplasms
Preclinical antitumor activity of the orally available heat shock protein 90 inhibitor NVP-BEP800.
Neoplasms
Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL.
Neoplasms
Preclinical pharmacokinetics and metabolism of a novel diaryl pyrazole resorcinol series of heat shock protein 90 inhibitors.
Neoplasms
Preclinical toxicity of a geldanamycin analog, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG), in rats and dogs: potential clinical relevance.
Neoplasms
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.
Neoplasms
Prediction of new Hsp90 inhibitors based on 3,4-isoxazolediamide scaffold using QSAR study, molecular docking and molecular dynamic simulation.
Neoplasms
Preferential sensitization of tumor cells to radiation by heat shock protein 90 inhibitor geldanamycin.
Neoplasms
Preoperative heat shock protein 47 levels identify colorectal cancer patients with lymph node metastasis and poor prognosis.
Neoplasms
Preparation of a heat-shock protein 70-based vaccine from DC-tumor fusion cells.
Neoplasms
Presence of heat shock protein 47-positive fibroblasts in cancer stroma is associated with increased risk of postoperative recurrence in patients with lung cancer.
Neoplasms
Presence of MLH1 protein aggravates the potential of the HSP90 inhibitor radicicol to sensitize tumor cells to cisplatin.
Neoplasms
Preventing tumor progression to the bone by induced tumor-suppressing MSCs.
Neoplasms
Prevention of brefeldin A-induced resistance to teniposide by the proteasome inhibitor MG-132: involvement of NF-kappaB activation in drug resistance.
Neoplasms
Prevention of Doxorubicin cardiopathic changes by a benzyl styryl sulfone in mice.
Neoplasms
Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model.
Neoplasms
Preventive effect of phytoglycoprotein (27 kDa) on inflammatory factors at liver injury in cadmium chloride-exposed ICR mice.
Neoplasms
Preventive effect of phytoglycoprotein (27?kDa) on inflammatory factors at liver injury in cadmium chloride-exposed ICR mice.
Neoplasms
Primary cell cultures arising from normal kidney and renal cell carcinoma retain the proteomic profile of corresponding tissues.
Neoplasms
Primary glioblastoma multiforme tumors and recurrence : Comparative analysis of the danger signals HMGB1, HSP70, and calreticulin.
Neoplasms
Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90.
Neoplasms
Priming polyvalent immunity by DNA vaccines expressing chimeric antigens with a stress protein-capturing, viral J-domain.
Neoplasms
PRKD2: A two-pronged kinase crucial for the tumor-supporting activity of HSP90.
Neoplasms
PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability.
Neoplasms
Proapoptotic Cyclic Peptide BC71 Targets Cell-Surface GRP78 and Functions as an Anticancer Therapeutic in Mice.
Neoplasms
Proapoptotic role of Hsp90 by its interaction with c-Jun N-terminal kinase in lipid rafts in edelfosine-mediated antileukemic therapy.
Neoplasms
Probing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics.
Neoplasms
Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.
Neoplasms
Production of a Mouse Monoclonal Antibody Against Mortalin by Whole Cell Immunization.
Neoplasms
Production of heat shock proteins, cytokines, and nitric oxide in toxic stress.
Neoplasms
Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models.
Neoplasms
Profiling protein markers associated with the sensitivity to concurrent chemoradiotherapy in human cervical carcinoma.
Neoplasms
Progesterone receptor chaperone complex-based high-throughput screening assay: identification of capsaicin as an inhibitor of the Hsp90 machine.
Neoplasms
Prognostic evaluation of p53, heat shock protein 70, Ki67, and CD34 expression in cancer of the tongue in Tunisia.
Neoplasms
Prognostic role of BiP/GRP78 expression as ER stress in patients with gastric adenocarcinoma.
Neoplasms
Prognostic significance of GRP78 expression patterns in breast cancer patients receiving adjuvant chemotherapy.
Neoplasms
Prognostic significance of heat shock protein 105 in lung adenocarcinoma.
Neoplasms
Prognostic significance of heat shock protein 70 expression in early gastric carcinoma.
Neoplasms
Prognostic significance of heat shock protein 90AA1 (HSP90?) in invasive breast cancer.
Neoplasms
Prognostic significance of heat shock proteins HSP70 and HSP90 in endometrial carcinomas.
Neoplasms
Prognostic Significance of the Hsp70 Gene Family in Colorectal Cancer.
Neoplasms
Prognostic value of Mortalin correlates with roles in epithelial-mesenchymal transition and angiogenesis in lung adenocarcinoma.
Neoplasms
Progression of the role of CRYAB in signaling pathways and cancers.
Neoplasms
Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells.
Neoplasms
Prolonged Endoplasmic Reticulum-Stressed Hepatocytes Drive an Alternative Macrophage Polarization.
Neoplasms
Promising Targets and Current Clinical Trials in Metastatic Non-Squamous NSCLC.
Neoplasms
Prophylactic Antitumor Effect of Mixed Heat Shock Proteins/Peptides in Mouse Sarcoma.
Neoplasms
Prospective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.
Neoplasms
Prostate cancer serum biomarker discovery through proteomic analysis of alpha-2 macroglobulin protein complexes.
Neoplasms
Proteasome inhibitors differentially affect heat shock protein response in cancer cells.
Neoplasms
Protection of zinc against tumor necrosis factor induced lethal inflammation depends on heat shock protein 70 and allows safe antitumor therapy.
Neoplasms
Protective antitumor immunity induced by tumor cell lysates conjugated with diphtheria toxin and adjuvant epitope in mouse breast tumor models.
Neoplasms
Protective effect of gentiopicroside from Gentiana macrophylla Pall. in ethanol-induced gastric mucosal injury in mice.
Neoplasms
Protective Effect of Naringenin against Lipopolysaccharide-Induced Acute Lung Injury in Rats.
Neoplasms
Protective effect of resveratrol against hepatic damage induced by heat stress in a rat model is associated with the regulation of oxidative stress and inflammation.
Neoplasms
Protective effects of noradrenaline against tumor necrosis factor-alpha-induced apoptosis in cultured rat brown adipocytes: role of nitric oxide-induced heat shock protein 70 expression.
Neoplasms
Protective role of Hsp27 protein against gamma radiation-induced apoptosis and radiosensitization effects of Hsp27 gene silencing in different human tumor cells.
Neoplasms
Protein chaperones: a composition of matter review (2008 - 2013).
Neoplasms
Protein expression during lag phase and growth initiation in Saccharomyces cerevisiae.
Neoplasms
Protein Expression Profile using Two-Dimensional Gel Analysis in Squamous Cervical Cancer Patients.
Neoplasms
Protein expression profiling in the spectrum of renal cell carcinomas.
Neoplasms
Protein kinase C delta regulates the phosphorylation of heat shock protein 27 in human hepatocellular carcinoma.
Neoplasms
Protein profile changes in the human breast cancer cell line MCF-7 in response to SEL1L gene induction.
Neoplasms
Protein profile of MCF-7 breast cancer cell line treated with lectin delivered by CaCO3NPs revealed changes in molecular chaperones, cytoskeleton, and membrane-associated proteins.
Neoplasms
Proteins of the Nucleolus of Dictyostelium discoideum: Nucleolar Compartmentalization, Targeting Sequences, Protein Translocations and Binding Partners.
Neoplasms
Proteome analysis and functional expression identify mortalin as an antiapoptotic gene induced by elevation of [Na+]i/[K+]i ratio in cultured vascular smooth muscle cells.
Neoplasms
Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA).
Neoplasms
Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2.
Neoplasms
Proteome changes in caco-2 cells treated with monascus-fermented red mold rice extract.
Neoplasms
Proteome changes in ovarian epithelial cells derived from women with BRCA1 mutations and family histories of cancer.
Neoplasms
Proteome-wide analysis of head and neck squamous cell carcinomas using laser-capture microdissection and tandem mass spectrometry.
Neoplasms
Proteomic analysis in endometrial cancer and endometrial hyperplasia tissues by 2D-DIGE technique.
Neoplasms
Proteomic analysis of cancer tissues: shedding light on carcinogenesis and possible biomarkers.
Neoplasms
Proteomic analysis of proteome and histone post-translational modifications in heat shock protein 90 inhibition-mediated bladder cancer therapeutics.
Neoplasms
Proteomic analysis of the copper ion-induced stress response in a human embryonic carcinoma cell line.
Neoplasms
Proteomic analysis of vascular smooth muscle cells treated with ouabain.
Neoplasms
Proteomic and Functional Analyses Reveal a Dual Molecular Mechanism Underlying Arsenic-Induced Apoptosis in Human Multiple Myeloma Cells.
Neoplasms
Proteomic and PROTEOMEX profiling of mammary cancer progression in a HER-2/neu oncogene-driven animal model system.
Neoplasms
Proteomic characterization of pancreatic islet {beta}-cells stimulated with pancreatic carcinoma cell conditioned medium.
Neoplasms
Proteomic detection of changes in protein synthesis induced by fibroblast growth factor-2 in MCF-7 human breast cancer cells.
Neoplasms
Proteomic identification and characterization of Ctenopharyngodon idella tumor necrosis factor receptor-associated protein 1 (CiTrap1): An anti-apoptosis factor upregulated by grass carp reovirus infection.
Neoplasms
Proteomic interrogation of HSP90 and insights for medical research.
Neoplasms
Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells.
Neoplasms
Proteomic investigation of human burn wounds by 2D-difference gel electrophoresis and mass spectrometry.
Neoplasms
Proteomic Profile of Sorafenib Resistance in Hepatocellular Carcinoma; GRP78 Expression Is Associated With Inferior Response to Sorafenib.
Neoplasms
Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values.
Neoplasms
Proteomic profiling of murine oocyte maturation.
Neoplasms
Proteomic profiling of the effect of prostate-specific antigen on prostate cancer cells.
Neoplasms
Proteomic profiling reveals that resveratrol inhibits HSP27 expression and sensitizes breast cancer cells to doxorubicin therapy.
Neoplasms
Proteomics-based identification of HSP60 as a tumor-associated antigen in colorectal cancer.
Neoplasms
Proteomics-based identification of HSP60 as a tumor-associated antigen in early stage breast cancer and ductal carcinoma in situ.
Neoplasms
Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib.
Neoplasms
Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r.
Neoplasms
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Neoplasms
Pterostilbene in Cancer Therapy.
Neoplasms
Pterostilbene-induced tumor cytotoxicity: a lysosomal membrane permeabilization-dependent mechanism.
Neoplasms
PTHrP [67-86] regulates the expression of stress proteins in breast cancer cells inducing modifications in urokinase-plasminogen activator and MMP-1 expression.
Neoplasms
Pu-erh Tea Inhibits Tumor Cell Growth by Down-Regulating Mutant p53.
Neoplasms
PU-H71 effectively induces degradation of I?B kinase ? in the presence of TNF-?.
Neoplasms
PU-H71, a novel Hsp90 inhibitor, as a potential cancer-specific sensitizer to carbon-ion beam therapy.
Neoplasms
Puerarin enhances intestinal function in piglets infected with porcine epidemic diarrhea virus.
Neoplasms
Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.
Neoplasms
Purification of heat shock protein 70-associated tumor peptides and their antitumor immunity to hepatoma in mice.
Neoplasms
Purification of multiple heat shock proteins from a single tumor sample.
Neoplasms
Purification of proteins for crystallographic applications.
Neoplasms
Purine-scaffold Hsp90 inhibitors.
Neoplasms
Purine-Scaffold Hsp90 Inhibitors.
Neoplasms
Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis.
Neoplasms
Quantitative analysis of hormones and inflammatory cytokines in Chlamydia trachomatis-infected women with tubal ectopic pregnancy and early intrauterine pregnancy.
Neoplasms
Quantitative analysis of the interplay between hsc70 and its co-chaperone HspBP1.
Neoplasms
Quantitative assessment of hsp70, IL-1? and TNF-? in the spinal cord of dogs with E40K SOD1-associated degenerative myelopathy.
Neoplasms
Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.
Neoplasms
Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma.
Neoplasms
Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.
Neoplasms
Quantitative proteomics reveals that hsp90 inhibition preferentially targets kinases and the DNA damage response.
Neoplasms
Quantitative score modulation of HSP90 and HSP27 in clear cell renal cell carcinoma.
Neoplasms
Quantum dot-based mortalin staining as a visual assay for detection of induced senescence in cancer cells.
Neoplasms
Quercetin Enhances Chemosensitivity to Gemcitabine in Lung Cancer Cells by Inhibiting Heat Shock Protein 70 Expression.
Neoplasms
Quercetin Mediated Reduction of Angiogenic Markers and Chaperones in DLA-Induced Solid Tumours.
Neoplasms
Quercetin sensitizes cells in a tumour-like low pH environment to hyperthermia.
Neoplasms
Quercetin-Induced Cell Death in Human Papillary Thyroid Cancer (B-CPAP) Cells.
Neoplasms
Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
Neoplasms
Radanamycin, a macrocyclic chimera of radicicol and geldanamycin.
Neoplasms
Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages.
Neoplasms
Radiation treatment of acute inflammation in mice.
Neoplasms
Radicicol potentiates heat-induced cell killing in a human oesophageal cancer cell line: the Hsp90 chaperone complex as a new molecular target for enhancement of thermosensitivity.
Neoplasms
Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins.
Neoplasms
Radioactive iodine labeling of monoclonal antibody against Hsp90? and its use in diagnostic imaging in prostate cancer xenograft model.
Neoplasms
Radiochemotherapy combined with NK cell transfer followed by second-line PD-1 inhibition in a patient with NSCLC stage IIIb inducing long-term tumor control: a case study.
Neoplasms
Radiofrequency ablation combined with liposomal quercetin to increase tumour destruction by modulation of heat shock protein production in a small animal model.
Neoplasms
Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition.
Neoplasms
Radiosensitization of human lung cancer cells by the novel purine-scaffold Hsp90 inhibitor, PU-H71.
Neoplasms
Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1?.
Neoplasms
Radiosensitization of wildtype p53 cancer cells by the MDM2-inhibitor PXN727 is associated with altered heat shock protein 70 (Hsp70) levels.
Neoplasms
Radiosensitizing effect of the novel Hsp90 inhibitor NVP-AUY922 in human tumour cell lines silenced for Hsp90?.
Neoplasms
Radiosynthesis of the iodine-124 labeled Hsp90 inhibitor PU-H71.
Neoplasms
Radiosynthesis of [(18)F]fluoromethyldeoxyspergualin for molecular imaging of heat shock proteins.
Neoplasms
Radiosynthesis, biological evaluation and preliminary microPET study of 18F-labeled 5-resorcinolic triazolone derivative based on ganetespib targeting HSP90.
Neoplasms
Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide.
Neoplasms
Rapid synthesis of a Bi@ZIF-8 composite nanomaterial as a near-infrared-II (NIR-II) photothermal agent for the low-temperature photothermal therapy of hepatocellular carcinoma.
Neoplasms
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1.
Neoplasms
Rational design of shepherdin, a novel anticancer agent.
Neoplasms
Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.
Neoplasms
Re: First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors.
Neoplasms
Reaction of Geldanamycin and C17-Substituted Analogues with Glutathione: Product Identifications and Pharmacological Implications.
Neoplasms
Reactivity of gamma delta T cells induced by the tumour cell line RPMI 8226: functional heterogeneity of clonal populations and role of GroEL heat shock proteins.
Neoplasms
Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation.
Neoplasms
Recent advances in heat shock protein-based cancer vaccines.
Neoplasms
Recent advances in Hsp90 inhibitors as antitumor agents.
Neoplasms
Recent Advances in Stereoselective Drug Targeting.
Neoplasms
Recent Advances in the Discovery of Novel HSP90 Inhibitors: An Update from 2014.
Neoplasms
Recent Patents on Heat Shock Proteins Targeting Antibodies.
Neoplasms
Recent update on discovery and development of Hsp90 inhibitors as senolytic agents.
Neoplasms
Recent updates on the development of ganetespib as a Hsp90 inhibitor.
Neoplasms
Receptor-recognized ??-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
Neoplasms
Recognition and killing of tumour cells expressing heat shock protein 65 kD with immunotoxins containing saporin.
Neoplasms
Recombinant adeno-associated virus encoding Epstein-Barr virus latent membrane proteins fused with heat shock protein as a potential vaccine for nasopharyngeal carcinoma.
Neoplasms
Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer.
Neoplasms
Recombinant heat shock protein 70 in combination with radiotherapy as a source of tumor antigens to improve dendritic cell immunotherapy.
Neoplasms
Recombinant Production and Characterization of SAC, the Core Domain of Par-4, by SUMO Fusion System.
Neoplasms
Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins--identification of additional interacting regions.
Neoplasms
Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer.
Neoplasms
Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology.
Neoplasms
Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90.
Neoplasms
Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells.
Neoplasms
Reduced Number of Lymphocytes by X-ray Irradiation: A Problem in a Combination Therapy Trial that Elicits the Abscopal Effect in Preclinical Studies Using Electron Beam Irradiation.
Neoplasms
Reduced survivin expression and tumor cell survival during chronic hypoxia and further cytotoxic enhancement by the cyclooxygenase-2 inhibitor celecoxib.
Neoplasms
Reflections and Outlook on Targeting HSP90, HSP70 and HSF1 in Cancer: A Personal Perspective.
Neoplasms
Regression of intestinal adenomas by vaccination with heat shock protein 105-pulsed bone marrow-derived dendritic cells in Apc(Min/+) mice.
Neoplasms
Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70.
Neoplasms
Regulation of CD23 in the chronic inflammatory response in asthma: a role for interferon-gamma and heat shock protein 70 in the TH2 environment.
Neoplasms
Regulation of heat shock protein 70 gene expression by c-myc.
Neoplasms
Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase.
Neoplasms
Regulation of proliferation and gene expression in cultured human aortic smooth muscle cells by resveratrol and standardized grape extracts.
Neoplasms
Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing's Disease.
Neoplasms
Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone.
Neoplasms
Regulation of tumor cell mitochondrial homeostasis by an organelle-specific hsp90 chaperone network.
Neoplasms
Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery.
Neoplasms
Regulatory processes affecting androgen receptor expression, stability, and function: potential targets to treat hormone-refractory prostate cancer.
Neoplasms
Relationship between 90-kilodalton heat shock protein, estrogen receptor, and progesterone receptor in human mammary tumors.
Neoplasms
Relationship between defective mouse mammary tumor virus envelope glycoprotein synthesis and GRP78 synthesis in glucocorticoid-treated mouse lymphoma cells. Evidence for translational control of GRP78 synthesis.
Neoplasms
Relevance of mortalin to cancer cell stemness and cancer therapy.
Neoplasms
Reliability of HSP70 (HSPA) expression as a prognostic marker in glioma.
Neoplasms
Reliability of tumor markers, chemokines, and metastasis-related molecules in serum.
Neoplasms
Removing the cells from adult bone marrow derived stem cell therapy does not eliminate cardioprotection.
Neoplasms
Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells.
Neoplasms
Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I.
Neoplasms
Reproducibility of fluid-phase measurements in PBS-treated sputum supernatant of healthy and stable COPD subjects.
Neoplasms
Reptin drives tumour progression and resistance to chemotherapy in nonsmall cell lung cancer.
Neoplasms
Repurposing L-Menthol for Systems Medicine and Cancer Therapeutics? L-Menthol Induces Apoptosis through Caspase 10 and by Suppressing HSP90.
Neoplasms
Requirement for endogenous heat shock factor 1 in inducible nitric oxide synthase induction in murine microglia.
Neoplasms
Research resource: enhanced genome-wide occupancy of estrogen receptor ? by the cochaperone p23 in breast cancer cells.
Neoplasms
Resistance exercise training-induced muscle hypertrophy was associated with reduction of inflammatory markers in elderly women.
Neoplasms
Resistance to HSP90 inhibition involving loss of MCL1 addiction.
Neoplasms
Response to hepatocarcinoma hca-f of mice immunized with heat shock protein 70 from elemene combo tumor cell vaccine.
Neoplasms
Responses to surgical stress after esophagectomy: Gene expression of heat shock protein 70, toll-like receptor 4, tumor necrosis factor-? and inducible nitric oxide synthase.
Neoplasms
Restoration of MHC class I surface expression and endogenous antigen presentation by a molecular chaperone.
Neoplasms
Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways.
Neoplasms
RESULTS OF IMMUNOHISTOCHEMISTRY IN THE DIFFERENTIAL DIAGNOSIS OF EARLY HEPATOCELLULAR CARCINOMA AND NODULES WITH HIGH-GRADE DYSPLASIA IN PATIENTS WITH CIRRHOSIS.
Neoplasms
Retinoid- and sodium-butyrate--induced decrease in heat shock protein 70 membrane-positive tumor cells is associated with reduced sensitivity to natural killer cell lysis, growth delay, and altered growth morphology.
Neoplasms
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Neoplasms
Reversed expression of GRIM-1 and GRP78 in human non-small cell lung cancer.
Neoplasms
Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivo.
Neoplasms
RNAi of Grp78 may disturb the fusion of ICR mouse palate cultured in vitro.
Neoplasms
RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.
Neoplasms
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
Neoplasms
Role of BRCA1 in heat shock response.
Neoplasms
Role of heat shock protein 27 in regulation of glutathione system and apoptosis of Jurkat tumor cells and blood lymphocytes.
Neoplasms
Role of HSP60/HSP10 in Lung Cancer: Simple Biomarkers or Leading Actors?
Neoplasms
Role of Hsp70 in cancer growth and survival.
Neoplasms
Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement.
Neoplasms
Role of HSPA1L as a cellular prion protein stabilizer in tumor progression via HIF-1?/GP78 axis.
Neoplasms
Role of Human and Mouse HspB1 in Metastasis.
Neoplasms
Role of Krüppel-like factor 4 and heat shock protein 27 in cancer of the larynx.
Neoplasms
Role of membrane Hsp70 in radiation sensitivity of tumor cells.
Neoplasms
Role of mitochondrial network stabilisation by a human small heat shock protein in tumour malignancy.
Neoplasms
Role of protein kinase Cdelta in transmitting hypoxia signal to HSF and HIF-1.
Neoplasms
Role of scavenger receptors in the binding and internalization of heat shock protein 70.
Neoplasms
Role of the novel HSP90 inhibitor AUY922 in hepatocellular carcinoma: Potential for therapy.
Neoplasms
Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer and Neurological Disorders.
Neoplasms
Roles of GRP78 in physiology and cancer.
Neoplasms
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
Neoplasms
Romidepsin for the treatment of cutaneous T-cell lymphoma.
Neoplasms
Rose Bengal acetate photodynamic therapy (RBAc-PDT) induces exposure and release of Damage-Associated Molecular Patterns (DAMPs) in human HeLa cells.
Neoplasms
S-nitrosylation affects TRAP1 structure and ATPase activity and modulates cell response to apoptotic stimuli.
Neoplasms
Safety and activity of IT-139, a ruthenium-based compound, in patients with advanced solid tumours: a first-in-human, open-label, dose-escalation phase I study with expansion cohort.
Neoplasms
SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis.
Neoplasms
Salvianolic acid A inhibits tumor-associated angiogenesis by blocking GRP78 secretion.
Neoplasms
Screening of cytokines to enhance vaccine effects of heat shock protein 70-rich tumor cell lysate.
Neoplasms
Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells.
Neoplasms
Secreted GRP78 activates EGFR-SRC-STAT3 signaling and confers the resistance to sorafeinib in HCC cells.
Neoplasms
Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity.
Neoplasms
Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.
Neoplasms
Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases.
Neoplasms
Secreted heat shock protein-90 (Hsp90) in wound healing and cancer.
Neoplasms
Secreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer.
Neoplasms
Secretion of cytokines and heat shock protein (HspA1A) by ovarian cancer cells depending on the tumor type and stage of disease.
Neoplasms
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.
Neoplasms
Secretory Clusterin: A Promising Target for Chemoresistance of Hepatocellular Carcinoma.
Neoplasms
Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death.
Neoplasms
Selection and Characterization of Single Chain Antibody Fragments Specific for Hsp90 as a Potential Cancer Targeting Molecule.
Neoplasms
Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications.
Neoplasms
Selective cancer targeting via aberrant behavior of cancer cell-associated glucocorticoid receptor.
Neoplasms
Selective cytotoxic activity of valinomycin against HT-29 Human colon carcinoma cells via down-regulation of GRP78.
Neoplasms
Selective Cytotoxicity of Ponciri Fructus against Glucose-Deprived PANC-1 Human Pancreatic Cancer Cells via Blocking Activation of GRP78.
Neoplasms
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.
Neoplasms
Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells.
Neoplasms
Selective expression of immunogenic, virus-like particle-derived antibody-binding epitopes.
Neoplasms
Selective HSP90? inhibition results in TNF and TRAIL mediated HIF1? degradation.
Neoplasms
Selective Inhibition of the Hsp90? Isoform.
Neoplasms
Selective targeting of cancer cells using a hydrogen peroxide-activated Hsp90 inhibitor.
Neoplasms
Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function.
Neoplasms
Selenomethionine relieves inflammation in the chicken trachea caused by LPS though inhibiting the NF-?B pathway.
Neoplasms
Self-heat shock protein 60 induces tumour necrosis factor-alpha in monocyte-derived macrophage: possible role in chronic inflammatory periodontal disease.
Neoplasms
Senescence-associated HSP60 expression in normal human skin fibroblasts.
Neoplasms
Sensitization of (colon) cancer cells to death receptor related therapies: A report from the FP6-ONCODEATH research consortium.
Neoplasms
Sensitization of lung cancer cells by altered dimerization of HSP27.
Neoplasms
Sensitization of multidrug-resistant cancer cells to Hsp90 inhibitors by NSAIDs-induced apoptotic and autophagic cell death.
Neoplasms
Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1.
Neoplasms
Sensitization of TRAIL-resistant cells by inhibition of heat shock protein 90 with low-dose geldanamycin.
Neoplasms
Sensitizing tumor cells to radiation by targeting the heat shock response.
Neoplasms
Separation and identification of HSP-associated protein complexes from pancreatic cancer cell lines using 2D CN/SDS-PAGE coupled with mass spectrometry.
Neoplasms
Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivatives.
Neoplasms
Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins.
Neoplasms
Serum antibodies to the 27-kd heat shock protein in women with gynecologic cancers.
Neoplasms
Serum antibody response to the heat shock protein 60 of Chlamydia trachomatis in women with developing cervical cancer.
Neoplasms
Serum GRP78 as a Tumor Marker and Its Prognostic Significance in Non-Small Cell Lung Cancers: A Retrospective Study.
Neoplasms
Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma.
Neoplasms
Serum heat shock protein 27 levels in patients with hepatocellular carcinoma.
Neoplasms
Serum heat shock protein 70 levels and lung cancer risk: a case-control study nested in a large cohort study.
Neoplasms
Serum heat shock protein 90 as a future predictive biomarker in childhood acute lymphoblastic leukemia.
Neoplasms
Serum level of soluble 70-kD heat shock protein is associated with high mortality in patients with colorectal cancer without distant metastasis.
Neoplasms
Serum levels of anti-heat shock protein 27 antibodies in patients with chronic liver disease.
Neoplasms
Serum levels of HSP90 in the continuum of breast ductal and lobular lesions.
Neoplasms
Serum Tumor Markers for Early Diagnosis of Primary Hepatocellular Carcinoma.
Neoplasms
Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells.
Neoplasms
Sex differences play a role in cardiac endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis induced by pressure overload and thapsigargin.
Neoplasms
sFLT01 modulates invasion and metastasis in prostate cancer DU145 cells by inhibition of VEGF/GRP78/MMP2&9 axis.
Neoplasms
SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres.
Neoplasms
Shock block for improved immunotherapy.
Neoplasms
Shock the heat shock network.
Neoplasms
Short-hairpin RNA-mediated Heat shock protein 90 gene silencing inhibits human breast cancer cell growth in vitro and in vivo.
Neoplasms
Short-Wave Diathermy Pretreatment and Inflammatory Myokine Response After High-Intensity Eccentric Exercise.
Neoplasms
ShRNA-mediated gene silencing of Heat shock protein 70 inhibits human colon cancer cell growth in vitro and in vivo.
Neoplasms
ShRNA-mediated gene silencing of heat shock protein 70 inhibits human colon cancer growth.
Neoplasms
Sialic acid content of tissue specific gp96 and its potential role in modulating gp96-macrophage interactions.
Neoplasms
Sigma-1 Receptor Positron Emission Tomography: A New Molecular Imaging Approach Using (S)-(-)-[18F]Fluspidine in Glioblastoma.
Neoplasms
Signalling profile and antitumour activity of the novel Hsp90 inhibitor NVP-AUY922 in multiple myeloma.
Neoplasms
Significance of expression of heat shock protein90alpha in human gastric cancer.
Neoplasms
Significance of serum antibodies against HSP 60 and HSP 70 for the diagnostic of infectious diseases.
Neoplasms
Sildenafil triggers tumor lethality through altered expression of HSP90 and degradation of PKD2.
Neoplasms
Silence of HDAC6 suppressed esophageal squamous cell carcinoma proliferation and migration by disrupting chaperone function of HSP90.
Neoplasms
Silencing glucose-regulated protein 78 induced renal cell carcinoma cell line G1 cell-cycle arrest and resistance to conventional chemotherapy.
Neoplasms
Silencing heat shock protein 27 decreases metastatic behavior of human head and neck squamous cell cancer cells in vitro.
Neoplasms
Silencing of Glucose-Regulated Protein 78 (GRP78) Enhances Cell Migration Through the Upregulation of Vimentin in Hepatocellular Carcinoma Cells.
Neoplasms
Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors.
Neoplasms
Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell.
Neoplasms
Simultaneous binding of the anti-cancer IgM monoclonal antibody PAT-SM6 to low density lipoproteins and GRP78.
Neoplasms
Simultaneous detection of porcine cytokines by multiplex analysis: Development of magnetic bioplex assay.
Neoplasms
Simvastatin functions as a heat shock protein 90 inhibitor against triple-negative breast cancer.
Neoplasms
Single-cell RNA sequencing reveals that targeting HSP90 suppresses PDAC progression by restraining mitochondrial bioenergetics.
Neoplasms
Six weeks of voluntary wheel running modulates inflammatory protein (MCP-1, IL-6, and IL-10) and DAMP (Hsp72) responses to acute stress in white adipose tissue of lean rats.
Neoplasms
Small Heat Shock Protein as a Multifunctional Scaffold: Integrated Tumor Targeting and Caspase Imaging within a Single Cage.
Neoplasms
Small interfering RNA targeting heat shock protein 70 enhances chemosensitivity in human bladder cancer cells.
Neoplasms
Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
Neoplasms
Small Molecule Inhibitors to Disrupt Protein-protein Interactions of Heat Shock Protein 90 Chaperone Machinery.
Neoplasms
Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.
Neoplasms
Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159.
Neoplasms
Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer.
Neoplasms
Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead.
Neoplasms
SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells.
Neoplasms
SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
Neoplasms
SNP discovery and gene annotation in the surf clam Mesodesma donacium
Neoplasms
SNX-2112 Induces Apoptosis and Autophagy of Nara-H Cells.
Neoplasms
SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK.
Neoplasms
SNX-25a, a novel Hsp90 inhibitor, inhibited human cancer growth more potently than 17-AAG.
Neoplasms
SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase-dependent cancers.
Neoplasms
Solid lipid nanoparticles as a novel formulation approach for tanespimycin (17-AAG) against leishmania infections: Preparation, characterization and macrophage uptake.
Neoplasms
Solid-phase synthesis, characterization and RNAi activity of branch and hyperbranch siRNAs.
Neoplasms
Soluble B and T lymphocyte attenuator possesses antitumor effects and facilitates heat shock protein 70 vaccine-triggered antitumor immunity against a murine TC-1 cervical cancer model in vivo.
Neoplasms
Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme.
Neoplasms
Soluble heat-shock protein 27 in blood serum is a non-invasive prognostic biomarker for ovarian cancer.
Neoplasms
Soluble T cell immunoglobulin mucin domain 3 (sTim-3) in maternal sera: a potential contributor to immune regulation during pregnancy.
Neoplasms
Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.
Neoplasms
Somatic mutations of calreticulin in myeloproliferative neoplasms.
Neoplasms
Sp1 regulates Raf/MEK/ERK-induced p21(CIP1) transcription in TP53-mutated cancer cells.
Neoplasms
Spatiofunctional Dynamics of NKX3.1 to Safeguard the Prostate from Cancer.
Neoplasms
Specific peptides for the therapeutic targeting of oncogenes.
Neoplasms
Specific protein carbonylation in human breast cancer tissue compared to adjacent healthy epithelial tissue.
Neoplasms
Specific regulation of HSPs in human tumor cell lines by PSK.
Neoplasms
Sperm protein 17 is a novel marker for predicting cisplatin response in esophageal squamous cancer cell lines.
Neoplasms
Spirulina phycocyanin induces differential protein expression and apoptosis in SKOV-3 cells.
Neoplasms
Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors.
Neoplasms
Spotlight on 17-AAG as an Hsp90 inhibitor for molecular targeted cancer treatment.
Neoplasms
Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics.
Neoplasms
STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma.
Neoplasms
STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer.
Neoplasms
Stage 1 testing and pharmacodynamic evaluation of the HSP90 inhibitor alvespimycin (17-DMAG, KOS-1022) by the pediatric preclinical testing program.
Neoplasms
Steady-State Levels of Phosphorylated Mitogen-Activated Protein Kinase Kinase 1/2 Determined by Mortalin/HSPA9 and Protein Phosphatase 1 Alpha in KRAS and BRAF Tumor Cells.
Neoplasms
Stereospecific antitumor activity of radicicol oxime derivatives.
Neoplasms
Steroids from Helleborus caucasicus reduce cancer cell viability inducing apoptosis and GRP78 down-regulation.
Neoplasms
STI571 (Glivec) inhibits the interaction between c-KIT and heat shock protein 90 of the gastrointestinal stromal tumor cell line, GIST-T1.
Neoplasms
Stimulation of erythrocyte cell membrane scrambling by gedunin.
Neoplasms
Stimulation of the ATPase activity of Hsp90 by zerumbone modification of its cysteine residues destabilizes its clients and causes cytotoxicity.
Neoplasms
STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1?/VEGF signaling pathway.
Neoplasms
Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth.
Neoplasms
Strategies for Stalling Malignancy: Targeting Cancer's Addiction to Hsp90.
Neoplasms
Strategy of Virtual Screening Based Discovery of HSP90 C-terminal Inhibitors and Network Pharmacological Analysis.
Neoplasms
Stress and immune responses in skin of turbot (Scophthalmus maximus) under different stocking densities.
Neoplasms
Stress Augments Insulin Resistance and Prothrombotic State: Role of Visceral Adipose-Derived Monocyte Chemoattractant Protein-1.
Neoplasms
Stress Chaperone GRP-78 Functions in Mineralized Matrix Formation.
Neoplasms
Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells.
Neoplasms
Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis.
Neoplasms
Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway.
Neoplasms
Stress granule formation mediates the inhibition of colonic Hsp70 translation by interferon-gamma and tumor necrosis factor-alpha.
Neoplasms
Stress Induction of GRP78/BiP and Its Role in Cancer.
Neoplasms
Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells.
Neoplasms
Stress protein Hsp27 expression predicts the outcome in operated small cell lung carcinoma and large cell neuroendocrine carcinoma patients.
Neoplasms
Stress protein/peptide complexes derived from autologous tumor tissue as tumor vaccines.
Neoplasms
Stress Proteins and Cytokines are Urinary Biomarkers for Diagnosis and Staging of Bladder Cancer.
Neoplasms
Stress-induced phosphoprotein-1 maintains the stability of JAK2 in cancer cells.
Neoplasms
Stress-induced release of HSC70 from human tumors.
Neoplasms
Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.
Neoplasms
Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53.
Neoplasms
Structural and Computational Biology of the Molecular Chaperone Hsp90: from Understanding Molecular Mechanisms to Computer-Based Inhibitor Design.
Neoplasms
Structural and energetic insight into the interactions between the benzolactam inhibitors and tumor marker HSP90?.
Neoplasms
Structural and functional basis of protein phosphatase 5 substrate specificity.
Neoplasms
Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
Neoplasms
Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90.
Neoplasms
Structural basis of the radicicol resistance displayed by a fungal hsp90.
Neoplasms
Structural Determination of Three Different Series of Compounds as Hsp90 Inhibitors Using 3D-QSAR Modeling, Molecular Docking and Molecular Dynamics Methods.
Neoplasms
Structural ensemble-based docking simulation and biophysical studies discovered new inhibitors of Hsp90 N-terminal domain.
Neoplasms
Structural insights into tumor-specific chaperoning activity of gamma synuclein in protecting estrogen receptor alpha 36 and its role in tamoxifen resistance in breast cancer.
Neoplasms
Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy.
Neoplasms
Structure based design of heat shock protein 90 inhibitors acting as anticancer agents.
Neoplasms
Structure of the ATP-binding domain of Plasmodium falciparum Hsp90.
Neoplasms
Structure prediction, expression and antigenicity of c-terminal of GRP78.
Neoplasms
Structure, function and regulation of the hsp90 machinery.
Neoplasms
Structure, Function, and Regulation of the Hsp90 Machinery.
Neoplasms
Structure-activity relationship of Garcinia xanthones analogues: Potent Hsp90 inhibitors with cytotoxicity and antiangiogenesis activity.
Neoplasms
Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms.
Neoplasms
Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors.
Neoplasms
Structure-based and in silico design of Hsp90 inhibitors.
Neoplasms
Structure-based design, synthesis, and biological evaluation of Hsp90?-selective inhibitors.
Neoplasms
Structure-based optimization of GRP78-binding peptides that enhances efficacy in cancer imaging and therapy.
Neoplasms
Structure-guided cancer blockade between bioactive bursehernin and proteins: Molecular docking and molecular dynamics study.
Neoplasms
Structure-guided design of an Hsp90? N-terminal isoform-selective inhibitor.
Neoplasms
Study of single nucleotide polymorphisms of tumour necrosis factors and HSP genes in nasopharyngeal carcinoma in North East India.
Neoplasms
Study on the anti-tumor efficacy induced by heat shock protein 70-peptide complexes derived from tumor cells.
Neoplasms
Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms.
Neoplasms
Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells.
Neoplasms
Submicroscopic deletion of 5q involving tumor suppressor genes (CTNNA1, HSPA9) and copy neutral loss of heterozygosity associated with TET2 and EZH2 mutations in a case of MDS with normal chromosome and FISH results.
Neoplasms
Sulforaphane Potentiates the Efficacy of 17-Allylamino 17-Demethoxygeldanamycin Against Pancreatic Cancer Through Enhanced Abrogation of Hsp90 Chaperone Function.
Neoplasms
Sulfoxythiocarbamate S-4 inhibits HSP90 in human cutaneous squamous cell carcinoma cells.
Neoplasms
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation.
Neoplasms
SUMOylation of HSP27 by small ubiquitin-like modifier 2/3 promotes proliferation and invasion of hepatocellular carcinoma cells.
Neoplasms
Supplementation of Moringa oleifera leaf powder orally improved productive performance by enhancing the intestinal health in rabbits under chronic heat stress.
Neoplasms
Supplementation of postbiotic RI11 improves antioxidant enzyme activity, upregulated gut barrier genes, and reduced cytokine, acute phase protein, and heat shock protein 70 gene expression levels in heat-stressed broilers.
Neoplasms
Suppression of Heat Shock Protein 27 Using OGX-427 Induces Endoplasmic Reticulum Stress and Potentiates Heat Shock Protein 90 Inhibitors to Delay Castrate-resistant Prostate Cancer.
Neoplasms
Suppression of heat shock protein 70 by siRNA enhances the antitumor effects of cisplatin in cultured human osteosarcoma cells.
Neoplasms
Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor.
Neoplasms
Suppression of stress protein GRP78 induction in tumor B/C10ME eliminates resistance to cell mediated cytotoxicity.
Neoplasms
Suppression of the transformed phenotype and induction of differentiation-like characteristics in cultured ovarian tumor cells by chronic treatment with progesterone.
Neoplasms
Suppression of tumor necrosis factor receptor-associated protein 1 expression induces inhibition of cell proliferation and tumor growth in human esophageal cancer cells.
Neoplasms
Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex.
Neoplasms
Surface staining and cytotoxic activity of heat-shock protein 60 antibody in stressed aortic endothelial cells.
Neoplasms
Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy.
Neoplasms
Survivin-Mediated Cancer Cell Migration Through GRP78 and Epithelial-Mesenchymal Transition (EMT) Marker Expression in Mahlavu Cells.
Neoplasms
Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response.
Neoplasms
SUV39H1 is a New Client Protein of Hsp90 Degradated by Chaetocin as a Novel C-Terminal Inhibitor of Hsp90.
Neoplasms
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.
Neoplasms
Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide.
Neoplasms
Synergistic action of the novel HSP90 inhibitor NVP-AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma.
Neoplasms
Synergistic Activity of the HSP90 Inhibitor Ganetespib With Lapatinib Reverses Acquired Lapatinib Resistance in HER2-Positive Breast Cancer Cells.
Neoplasms
Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models.
Neoplasms
Synergistic Antipancreatic Tumor Effect by Simultaneously Targeting Hypoxic Cancer Cells With HSP90 Inhibitor and Glycolysis Inhibitor.
Neoplasms
Synergistic effects of geldanamycin and antitumor drugs.
Neoplasms
Synergistic effects of heat and ET-18-OCH3 on membrane expression of hsp70 and lysis of leukemic K562 cells.
Neoplasms
Synergistic effects of rmhTRAIL and 17-AAG on the proliferation and apoptosis of multiple myeloma cells.
Neoplasms
Synergistic enhancement of cancer therapy using a combination of heat shock protein targeted HPMA copolymer-drug conjugates and gold nanorod induced hyperthermia.
Neoplasms
Synergistic interaction of hyperthermia and gemcitabine in lung cancer.
Neoplasms
Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70.
Neoplasms
Synergy of hypoxia relief and heat shock protein inhibition for phototherapy enhancement.
Neoplasms
Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78.
Neoplasms
Synthesis and biological evaluation of 3,5-disubstituted-4-alkynylisoxozales as a novel class of HSP90 inhibitors.
Neoplasms
Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.
Neoplasms
Synthesis and Biological Evaluation of Celastrol Derivatives with Improved Cytotoxic Selectivity and Antitumor Activities.
Neoplasms
Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors.
Neoplasms
Synthesis and biological evaluation of geldanamycin analogs against human cancer cells.
Neoplasms
Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.
Neoplasms
Synthesis and evaluation of cell-permeable biotinylated PU-H71 derivatives as tumor Hsp90 probes.
Neoplasms
Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors.
Neoplasms
Synthesis and in vitro antiproliferative activity of C5-benzyl substituted 2-amino-pyrrolo[2,3-d]pyrimidines as potent Hsp90 inhibitors.
Neoplasms
Synthesis and Photophysical and Photocatalytic Properties of a Highly Fluorinated and Durable Phthalocyanine-Peptide Bioconjugate for Potential Theranostic Applications.
Neoplasms
Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay.
Neoplasms
Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90.
Neoplasms
Synthesis of a versatile metacyclophane macrolactam.
Neoplasms
Synthesis of novel dual target inhibitors of PARP and HSP90 and their antitumor activities.
Neoplasms
Synthesis of potential allosteric modulators of Hsp90 by chemical glycosylation of Eupomatenoid-6.
Neoplasms
Synthesis of reblastatin, autolytimycin, and non-benzoquinone analogues: potent inhibitors of heat shock protein 90.
Neoplasms
Synthesis, G-Quadruplex Stabilisation, Docking Studies, and Effect on Cancer Cells of Indolo[3,2-b]quinolines with One, Two, or Three Basic Side Chains.
Neoplasms
Synthetic affibody molecules: a novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors.
Neoplasms
Synthetic Antibody Mimics Based on Cancer-Targeting Immunostimulatory Peptides.
Neoplasms
Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton: Promising antibreast cancer agent.
Neoplasms
Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells.
Neoplasms
Synthetic small interfering RNA targeting heat shock protein 105 induces apoptosis of various cancer cells both in vitro and in vivo.
Neoplasms
Synuclein ? protects Akt and mTOR and renders tumor resistance to Hsp90 disruption.
Neoplasms
Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption.
Neoplasms
Systematic identification of the HSP90 regulated proteome.
Neoplasms
Systemic Par-4 inhibits non-autochthonous tumor growth.
Neoplasms
T cell activation by heat shock protein 70 vaccine requires TLR signaling and scavenger receptor expressed by endothelial cells-1.
Neoplasms
Tanespimycin monotherapy in relapsed multiple myeloma: results of a phase 1 dose-escalation study.
Neoplasms
Tanespimycin: the opportunities and challenges of targeting heat shock protein 90.
Neoplasms
Targeted cancer therapy through 17-DMAG as an Hsp90 inhibitor: Overview and current state of the art.
Neoplasms
Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is highly active against pancreatic cancer models.
Neoplasms
Targeted delivery of heat shock protein 90 inhibitors prevents growth of HER2-positive tumor.
Neoplasms
Targeted hyperthermia using magnetite cationic liposomes and an alternating magnetic field in a mouse osteosarcoma model.
Neoplasms
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Neoplasms
Targeted Inhibition of Heat Shock Protein 90 Suppresses Tumor Necrosis Factor-? and Ameliorates Murine Intestinal Inflammation.
Neoplasms
Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes.
Neoplasms
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease.
Neoplasms
Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer.
Neoplasms
Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling.
Neoplasms
Targeted near infrared hyperthermia combined with immune stimulation for optimized therapeutic efficacy in thyroid cancer treatment.
Neoplasms
Targeted therapies with chemoradiation in esophageal cancer: development and future directions.
Neoplasms
Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets.
Neoplasms
Targeted-delivery of siRNA via a polypeptide-modified liposome for the treatment of gp96 over-expressed breast cancer.
Neoplasms
Targeting Aerobic Glycolysis and HIF-1alpha Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells.
Neoplasms
Targeting Cancer Metabolism Breaks Radioresistance by Impairing the Stress Response.
Neoplasms
Targeting Cdc37 inhibits multiple signaling pathways and induces growth arrest in prostate cancer cells.
Neoplasms
Targeting CDC37: an alternative, kinase-directed strategy for disruption of oncogenic chaperoning.
Neoplasms
Targeting chaperones in transformed systems--a focus on Hsp90 and cancer.
Neoplasms
Targeting CK2-driven non-oncogene addiction in B-cell tumors.
Neoplasms
Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization.
Neoplasms
Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts.
Neoplasms
Targeting gene expression to tumor cells with loss of wild-type p53 function.
Neoplasms
Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing p53-mediated apoptosis in hepatocellular carcinoma.
Neoplasms
Targeting GRP78 enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide-? methyl ester-mediated photodynamic therapy via the Wnt/?-catenin signaling pathway.
Neoplasms
Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo.
Neoplasms
Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment?
Neoplasms
Targeting heat shock protein 70 using gold nanorods enhances cancer cell apoptosis in low dose plasmonic photothermal therapy.
Neoplasms
Targeting heat shock protein 90 for anti-cancer drug development.
Neoplasms
Targeting Heat Shock Protein 90 in Pancreatic Cancer Impairs Insulin-like Growth Factor-I Receptor Signaling, Disrupts an Interleukin-6/Signal-Transducer and Activator of Transcription 3/Hypoxia-Inducible Factor-1{alpha} Autocrine Loop, and Reduces Orthotopic Tumor Growth.
Neoplasms
Targeting heat shock protein 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma.
Neoplasms
Targeting heat shock protein 90 with non-quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma.
Neoplasms
Targeting Heat Shock Proteins 60 and 70 of Toxoplasma gondii as a Potential Drug Target: In Silico Approach.
Neoplasms
Targeting Heat Shock Proteins 70/90 and Proteasome for Cancer Therap.
Neoplasms
Targeting heat shock proteins in cancer.
Neoplasms
Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach.
Neoplasms
Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand.
Neoplasms
Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors.
Neoplasms
Targeting Heat-Shock Protein 90 (HSP90) as a Complementary Strategy to Immune Checkpoint Blockade for Cancer Therapy.
Neoplasms
Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.
Neoplasms
Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer.
Neoplasms
Targeting heat-shock-protein 90 (Hsp90) by natural products: geldanamycin, a show case in cancer therapy.
Neoplasms
Targeting highly expressed extracellular HSP90 in breast cancer stem cells inhibits tumor growth in vitro and in vivo.
Neoplasms
Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia.
Neoplasms
Targeting HSF1 sensitizes cancer cells to HSP90 inhibition.
Neoplasms
Targeting HSP90 by the novel inhibitor NVP-AUY922 reduces growth and angiogenesis of pancreatic cancer.
Neoplasms
Targeting hsp90 family members: A strategy to improve cancer cell death.
Neoplasms
Targeting HSP90 for cancer therapy.
Neoplasms
Targeting Hsp90 for the treatment of cancer.
Neoplasms
Targeting Hsp90 in Non-Cancerous Maladies.
Neoplasms
Targeting Hsp90 in urothelial carcinoma.
Neoplasms
Targeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells.
Neoplasms
Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma.
Neoplasms
Targeting Hsp90: small-molecule inhibitors and their clinical development.
Neoplasms
Targeting HSPA8 inhibits proliferation via downregulating BCR-ABL and enhances chemosensitivity in imatinib-resistant chronic myeloid leukemia cells.
Neoplasms
Targeting KRAS-mutant non-small cell lung cancer with the Hsp90 inhibitor ganetespib.
Neoplasms
Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.
Neoplasms
Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors.
Neoplasms
Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells.
Neoplasms
Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes.
Neoplasms
Targeting multiple signal transduction pathways through inhibition of Hsp90.
Neoplasms
Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.
Neoplasms
Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.
Neoplasms
Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer.
Neoplasms
Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors.
Neoplasms
Targeting oral cancer stemness and chemoresistance by isoliquiritigenin-mediated GRP78 regulation.
Neoplasms
Targeting PI3K/Akt/HSP90 Signaling Sensitizes Gastric Cancer Cells to Deoxycholate-Induced Apoptosis.
Neoplasms
Targeting plasma membrane GRP78 for cancer growth inhibition.
Neoplasms
Targeting solid tumors via T cell receptor complementarity-determining region 3delta in an engineered antibody.
Neoplasms
Targeting survivin in cancer: the cell-signalling perspective.
Neoplasms
Targeting the Diabetic Chaperome to Improve Peripheral Neuropathy.
Neoplasms
Targeting the dynamic HSP90 complex in cancer.
Neoplasms
Targeting the entry region of Hsp90's ATP binding pocket with a novel 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl amide.
Neoplasms
Targeting the Extracellular HSP90 Co-Chaperone Morgana Inhibits Cancer Cell Migration and Promotes Anticancer Immunity.
Neoplasms
Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis.
Neoplasms
Targeting the GRP78 Pathway for Cancer Therapy.
Neoplasms
Targeting the heat shock protein 90: a rational way to inhibit macrophage migration inhibitory factor function in cancer.
Neoplasms
Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation.
Neoplasms
Targeting the Hsp90 chaperone: synthesis of novel resorcylic acid macrolactone inhibitors of Hsp90.
Neoplasms
Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studies.
Neoplasms
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies.
Neoplasms
Targeting the HSP90-CDC37-kinase chaperone cycle: A promising therapeutic strategy for cancer.
Neoplasms
Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions.
Neoplasms
Targeting the molecular chaperone heat shock protein 90 provides a multifaceted effect on diverse cell signaling pathways of cancer cells.
Neoplasms
Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition.
Neoplasms
Targeting the unfolded protein response in cancer therapy.
Neoplasms
Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA.
Neoplasms
Targeting to overexpressed glucose-regulated protein 78 in gastric cancer discovered by 2D DIGE improves the diagnostic and therapeutic efficacy of micelles-mediated system.
Neoplasms
Targeting tumour-supportive cellular machineries in anticancer drug development.
Neoplasms
Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.
Neoplasms
TAS-116, a highly selective inhibitor of heat shock protein 90? and ?, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models.
Neoplasms
TAS-116, a Novel Hsp90 Inhibitor, Selectively Enhances Radiosensitivity of Human Cancer Cells to X-rays and Carbon Ion Radiation.
Neoplasms
TAT-mediated gp96 transduction to APCs enhances gp96-induced antiviral and antitumor T cell responses.
Neoplasms
Technology evaluation: HSPPC-96, antigenics.
Neoplasms
Telomerase promotes formation of a telomere protective complex in cancer cells.
Neoplasms
Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines.
Neoplasms
Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells.
Neoplasms
Testicular superoxide dismutase activity, heat shock protein 70 concentration and blood plasma inhibin-alpha concentration of dogs with a Sertoli cell tumor in a unilateral cryptorchid testis.
Neoplasms
Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway.
Neoplasms
The 'peptidome' of tumour-derived chaperone-rich cell lysate anti-cancer vaccines reveals potential tumour antigens that stimulate tumour immunity.
Neoplasms
The 4C5 cell-impermeable anti-HSP90 antibody with anti-cancer activity, is composed of a single light chain dimer.
Neoplasms
The 60-kDa heat shock protein regulates energy rearrangement and protein synthesis to promote proliferation of multiple myeloma cells.
Neoplasms
The 8.1 ancestral MHC haplotype is associated with delayed onset of colonization in cystic fibrosis.
Neoplasms
The achilles heel of ErbB-2/HER2: regulation by the Hsp90 chaperone machine and potential for pharmacological intervention.
Neoplasms
The adenovirus E1B 19-kilodalton protein stimulates gene expression by increasing DNA levels.
Neoplasms
The Ameliorative Effects of Ascorbic Acid on Critical Illness Polyneuropathy in Rodent Sepsis Model.
Neoplasms
The analysis of chemotherapy resistance in human lung cancer cell line with microchip-based system.
Neoplasms
The Antagonistic Effect of Selenium on Lead-Induced Inflammatory Factors and Heat Shock Protein mRNA Level in Chicken Cartilage Tissue.
Neoplasms
The Antagonistic Effect of Selenium on Lead-Induced Inflammatory Factors and Heat Shock Proteins mRNA Expression in Chicken Livers.
Neoplasms
The anti-cancer drug cisplatin induces H25 in Ehrlich ascites tumor cells by a mechanism different from transcriptional stimulation influencing predominantly H25 translation.
Neoplasms
The anti-cancer IgM monoclonal antibody PAT-SM6 binds with high avidity to the unfolded protein response regulator GRP78.
Neoplasms
The Anti-Inflammatory Effects of the Small Molecule Pifithrin-µ on BV2 Microglia.
Neoplasms
The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors.
Neoplasms
The Application of the in-Situ Hyperthermia Emission from Acoustic Nanodroplets for Theranostic Dual-Imaging and Antitumor Modalities.
Neoplasms
The Association Between HSP90/topoisomerase I Immunophenotype and the Clinical Features of Colorectal Cancers in Respect to KRAS Gene Status.
Neoplasms
The association of elevated reactive oxygen species levels from neutrophils with low-grade inflammation in the elderly.
Neoplasms
The ATAD2/ANCCA homolog Yta7 cooperates with Scm3HJURP to deposit Cse4CENP-A at the centromere in yeast.
Neoplasms
The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.
Neoplasms
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin.
Neoplasms
The C-terminal half of heat shock protein 90 represents a second site for pharmacologic intervention in chaperone function.
Neoplasms
The cell surface GRP78 facilitates the invasion of hepatocellular carcinoma cells.
Neoplasms
The chaperone Hsp70 is a BH3 receptor activated by the pro-apoptotic Bim to stabilize anti-apoptotic clients.
Neoplasms
The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells.
Neoplasms
The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation.
Neoplasms
The chronic spleen injury of mice following long-term exposure to titanium dioxide nanoparticles.
Neoplasms
The clinical applications of heat shock protein inhibitors in cancer - present and future.
Neoplasms
The Clinical Value of HSP60 in Digestive System Cancers: a Systematic Review and Meta-Analysis.
Neoplasms
The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast.
Neoplasms
The co-chaperone p23 is degraded by caspases and the proteasome during apoptosis.
Neoplasms
The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis.
Neoplasms
The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells.
Neoplasms
The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities.
Neoplasms
The complex function of hsp70 in metastatic cancer.
Neoplasms
The conformation-specific Hsp90 inhibition interferes with the oncogenic RAF kinase adaptation and triggers premature cellular senescence, hence, acts as a tumor suppressor mechanism.
Neoplasms
The critical role of GRP78 in physiologic and pathologic stress.
Neoplasms
The DAC system and associations with multiple myeloma.
Neoplasms
The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Neoplasms
The Development of Hsp90?-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition.
Neoplasms
The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90.
Neoplasms
The disruption of protein-protein interactions with co-chaperones and client substrates as a strategy towards Hsp90 inhibition.
Neoplasms
The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex (CubipyOXA) leads to cell death in NCI-H292 cancer cells.
Neoplasms
The double edge of the HSP90-CDC37 chaperone machinery: opposing determinants of kinase stability and activity.
Neoplasms
The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer.
Neoplasms
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein.
Neoplasms
The effect of celastrol, a triterpene with antitumorigenic activity, on conformational and functional aspects of the human 90kDa heat shock protein Hsp90?, a chaperone implicated in the stabilization of the tumor phenotype.
Neoplasms
The effect of cisplatin, etoposide and quercetin on Hsp72 expression.
Neoplasms
The Effect of Continuous Sedation Therapy on Immunomodulation, Plasma Levels of Antioxidants, and Indicators of Tissue Repair in Post-Burn Sepsis Patients.
Neoplasms
The Effect of Heat Shock Protein 90 Inhibitor on Pain in Cancer Patients: A Systematic Review and Meta-Analysis.
Neoplasms
The effect of heat shock protein 90 inhibitors on histone 4 lysine 20 methylation in bladder cancer.
Neoplasms
The effect of heat shock, cisplatin, etoposide and quercetin on Hsp27 expression in human normal and tumour cells.
Neoplasms
The effect of quercetin on apoptosis and necrosis induction in human colon adenocarcinoma cell line LS180.
Neoplasms
The effect of simvastatin on the proteome of detergent-resistant membrane domains: Decreases of specific proteins previously related to cytoskeleton regulation, calcium homeostasis and cell fate.
Neoplasms
The effect of vaccination with the lysate of heat-shocked tumor cells on nitric oxide production in BALB/c mice with fibrosarcoma tumor.
Neoplasms
The effect of Zhangfei on the unfolded protein response and growth of cells derived from canine and human osteosarcomas.
Neoplasms
The effects inhibiting the proliferation of cancer cells by far-infrared radiation (FIR) are controlled by the basal expression level of heat shock protein (HSP) 70A.
Neoplasms
The effects of Ficus carica polysaccharide on immune response and expression of some immune-related genes in grass carp, Ctenopharyngodon idella.
Neoplasms
The effects of Hsp90 expression alteration on spinal metastases of breast carcinoma.
Neoplasms
The effects of KNK437, a novel inhibitor of heat shock protein synthesis, on the acquisition of thermotolerance in a murine transplantable tumor in vivo.
Neoplasms
The Effects of Mouse Recombinant Resistin on mRNA Expression of Proinflammatory and Anti-Inflammatory Cytokines and Heat Shock Protein-70 in Experimental Stroke Model.
Neoplasms
The effects of Natucin C-Natucin P mixture on blood biochemical parameters, antioxidant activity and non-specific immune responses in tilapia (Oreochromis niloticus).
Neoplasms
The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness.
Neoplasms
The Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer Therapeutics.
Neoplasms
The endoplasmic reticulum stress markers GRP78 and CHOP predict disease-free survival and responsiveness to chemotherapy in breast cancer.
Neoplasms
The Escherichia coli Subtilase Cytotoxin A Subunit Specifically Cleaves Cell-Surface GRP78 and Abolishes COOH-Terminal-Dependent Signaling.
Neoplasms
The estrogen-inducible transferrin receptor-like membrane glycoprotein is related to stress-regulated proteins.
Neoplasms
The expanding proteome of the molecular chaperone HSP90.
Neoplasms
The expression of HSP60 and HSP10 in large bowel carcinomas with lymph node metastase.
Neoplasms
The expression of HSP70 and HSP90alpha in children with Wilms tumor.
Neoplasms
The expression of mycobacterial heat shock protein (HSP64) on Meth A tumour cells.
Neoplasms
The expression of the molecular chaperone calnexin is decreased in cancer cells grown as colonies compared to monolayer.
Neoplasms
The expression profiles and prognostic values of HSP70s in hepatocellular carcinoma.
Neoplasms
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.
Neoplasms
The fungal Achilles' heel: targeting Hsp90 to cripple fungal pathogens.
Neoplasms
The G?-interacting vesicle-associated protein interacts with and promotes cell surface localization of GRP78 during endoplasmic reticulum stress.
Neoplasms
The geldanamycin analogue 17-allylamino-17-demethoxygeldanamycin inhibits the growth of GL261 glioma cells in vitro and in vivo.
Neoplasms
The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization.
Neoplasms
The heat shock protein 47 as a potential biomarker and a therapeutic agent in cancer research.
Neoplasms
The heat shock protein 90 chaperone complex: an evolving therapeutic target.
Neoplasms
The heat shock protein 90 inhibitor IPI-504 induces apoptosis of AKT-dependent diffuse large B-cell lymphomas.
Neoplasms
The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage and cell proliferation arrest in xenografts models of gastrointestinal stromal tumors.
Neoplasms
The heat shock protein 90 inhibitor, (-)-epigallocatechin gallate, has anticancer activity in a novel human prostate cancer progression model.
Neoplasms
The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line.
Neoplasms
The heat shock protein 90 inhibitor, AT13387, displays a long duration of action in vitro and in vivo in non-small cell lung cancer.
Neoplasms
The heat shock protein 90-binding geldanamycin inhibits cancer cell proliferation, down-regulates oncoproteins, and inhibits epidermal growth factor-induced invasion in thyroid cancer cell lines.
Neoplasms
The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands.
Neoplasms
The heat shock transcription factor 1 as a potential new therapeutic target in multiple myeloma.
Neoplasms
The hERG channel is dependent upon the Hsp90? isoform for maturation and trafficking.
Neoplasms
The hexameric structures of human heat shock protein 90.
Neoplasms
The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells.
Neoplasms
The Hsp70 inhibiting peptide aptamer A17 potentiates radiosensitization of tumor cells by Hsp90 inhibition.
Neoplasms
The HSP90 and DNA topoisomerase VI inhibitor radicicol also inhibits human type II DNA topoisomerase.
Neoplasms
The Hsp90 chaperone complex A potential target for cancer therapy?
Neoplasms
The Hsp90 chaperone complex as a novel target for cancer therapy.
Neoplasms
The HSP90 chaperone machinery.
Neoplasms
The Hsp90 chaperone machinery: from structure to drug development.
Neoplasms
The Hsp90 Co-chaperones Sti1, Aha1, and P23 Regulate Adaptive Responses to Antifungal Azoles.
Neoplasms
The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease.
Neoplasms
The HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin modulates radiosensitivity by downregulating serine/threonine kinase 38 via Sp1 inhibition.
Neoplasms
The HSP90 inhibitor 17-N-allylamino-17-demethoxy geldanamycin (17-AAG) synergizes with cisplatin and induces apoptosis in cisplatin-resistant esophageal squamous cell carcinoma cell lines via the Akt/XIAP pathway.
Neoplasms
The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer.
Neoplasms
The HSP90 inhibitor ganetespib synergizes with the MET kinase inhibitor crizotinib in both crizotinib-sensitive and -resistant MET-driven tumor models.
Neoplasms
The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine.
Neoplasms
The Hsp90 inhibitor IPI-504 rapidly lowers EML4-ALK levels and induces tumor regression in ALK-driven NSCLC models.
Neoplasms
The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-?B signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells.
Neoplasms
The HSP90 inhibitor NVP-AUY922-AG inhibits the PI3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells.
Neoplasms
The HSP90 inhibitor Onalespib exerts synergistic anti-cancer effects when combined with radiotherapy: an in vitro and in vivo approach.
Neoplasms
The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-?B and disruption of mitochondria-dependent pathways.
Neoplasms
The HSP90 Inhibitor, AT13387, Is Effective against Imatinib-Sensitive and -Resistant Gastrointestinal Stromal Tumor Models.
Neoplasms
The HSP90 molecular chaperone - an enigmatic ATPase.
Neoplasms
The Hsp90 molecular chaperone: an open and shut case for treatment.
Neoplasms
The human immunodeficiency virus protease inhibitor ritonavir is potentially active against urological malignancies.
Neoplasms
The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor.
Neoplasms
The immunological era in melanoma treatment: new challenges for heat shock protein-based vaccine in the advanced disease.
Neoplasms
The increase in the frequency of MICA gene A6 allele in oral squamous cell carcinoma.
Neoplasms
The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide.
Neoplasms
The influence of liposomal quercetin on liver damage induced by microwave ablation.
Neoplasms
The interaction of HspA1A with TLR2 and TLR4 in the response of neutrophils induced by ovarian cancer cells in vitro.
Neoplasms
The Involvement of Danger-Associated Molecular Patterns in the Development of Immunoparalysis in Cardiac Arrest Patients.
Neoplasms
The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.
Neoplasms
The matrix metalloproteinase 7 (MMP7) links Hsp90 chaperone with acquired drug resistance and tumor metastasis.
Neoplasms
The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.
Neoplasms
The mitochondrial chaperone protein TRAP1 mitigates ?-Synuclein toxicity.
Neoplasms
The Mitochondrial Chaperone TRAP1 as a Candidate Target of Oncotherapy.
Neoplasms
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase.
Neoplasms
The Mitochondrial Hsp90 TRAP1 and Alzheimer's Disease.
Neoplasms
The modulation of protein kinase A and heat shock protein 70 is involved in the reversible increase of blood-brain tumor barrier permeability induced by papaverine.
Neoplasms
The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment.
Neoplasms
The molecular chaperone TRAP1 in cancer: From the basics of biology to pharmacological targeting.
Neoplasms
The Natural Compound Cantharidin Induces Cancer Cell Death through Inhibition of Heat Shock Protein 70 (HSP70) and Bcl-2-associated Athanogene Domain 3 (BAG3) Expression by Blocking Heat Shock Factor 1 (HSF1) Binding to Promoters.
Neoplasms
The Natural Compound Oblongifolin C Exhibits Anticancer Activity by Inhibiting HSPA8 and Cathepsin B In Vitro.
Neoplasms
The natural human IgM antibody PAT-SM6 induces apoptosis in primary human multiple myeloma cells by targeting heat shock protein GRP78.
Neoplasms
The network interaction of the human cytosolic 90kDa heat shock protein Hsp90: A target for cancer therapeutics.
Neoplasms
The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells.
Neoplasms
The new platinum(IV) derivative LA-12 shows stronger inhibitory effect on Hsp90 function compared to cisplatin.
Neoplasms
The next generation of peptide receptor radionuclide therapy.
Neoplasms
The Noncompetitive Effect of Gambogic Acid Displaces Fluorescence-Labeled ATP but Requires ATP for Binding to Hsp90/HtpG.
Neoplasms
The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells.
Neoplasms
The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme.
Neoplasms
The novel HSP90 inhibitor STA-9090 exhibits activity against Kit-dependent and -independent malignant mast cell tumors.
Neoplasms
The Novel HSP90 Inhibitor, IPI-493, Is Highly Effective in Human Gastrostrointestinal Stromal Tumor Xenografts Carrying Heterogeneous KIT Mutations.
Neoplasms
The Novel Oral Hsp90 Inhibitor NVP-HSP990 Exhibits Potent and Broad-spectrum Antitumor Activities In Vitro and In Vivo.
Neoplasms
The odyssey of hsp60 from tumor cells to other destinations includes plasma membrane-associated stages and Golgi and exosomal protein-trafficking modalities.
Neoplasms
The opportunities and challenges of personalized genome-based molecular therapies for cancer: targets, technologies, and molecular chaperones.
Neoplasms
The Par-4-GRP78 TRAIL, more twists and turns.
Neoplasms
The physiological performance and immune response of juvenile turbot (Scophthalmus maximus) to nitrite exposure.
Neoplasms
The plant diterpene epoxysiderol targets Hsp70 in cancer cells, affecting its ATPase activity and reducing its translocation to plasma membrane.
Neoplasms
The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.
Neoplasms
The presence of anti-GRP78 antibodies in the serum of patients with colorectal carcinoma: a potential biomarker for early cancer detection.
Neoplasms
The protective role of selenium against cadmium-induced hepatotoxicity in laying hens: Expression of Hsps and inflammation-related genes and modulation of elements homeostasis.
Neoplasms
The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining.
Neoplasms
The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90.
Neoplasms
The rat 78,000 dalton glucose-regulated protein (GRP78) as a precursor for the rat steroidogenesis-activator polypeptide (SAP): the SAP coding sequence is homologous with the terminal end of GRP78.
Neoplasms
The reaction of posttransplant denervated liver on the hemorrhagic shock in rats.
Neoplasms
The regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancy.
Neoplasms
The regulatory mechanism of Hsp90alpha secretion from endothelial cells and its role in angiogenesis during wound healing.
Neoplasms
The relationship between three heat shock protein 70 gene polymorphisms and susceptibility to lung cancer.
Neoplasms
The Relationship of Immunoexpression of Ki-67 and Hsp70 with Clinical and Morphological Parameters and Prognosis of Papillary Thyroid Cancer.
Neoplasms
The release of Hsp70 from A431 carcinoma cells is mediated by secretory-like granules.
Neoplasms
The Right Tool for the Job: An Overview of Hsp90 Inhibitors.
Neoplasms
The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated ?2M.
Neoplasms
The role of calreticulin mutations in myeloproliferative neoplasms.
Neoplasms
The role of ferroptosis in digestive system cancer.
Neoplasms
The role of functional and molecular imaging in cancer drug discovery and development.
Neoplasms
The role of heat shock protein 90 in the regulation of tumor cell apoptosis.
Neoplasms
The role of heat shock proteins in cancer.
Neoplasms
The Role of Heat Shock Proteins in Leukemia.
Neoplasms
The Role of Heat Shock Proteins in Regulating Receptor Signal Transduction.
Neoplasms
The role of HSP90 in Quercetin-induced apoptosis in human papillary thyroid (B-CPAP) cancer cells.
Neoplasms
The role of HSP90 molecular chaperones in hepatocellular carcinoma.
Neoplasms
The role of N6-methyladenosine RNA methylation in the heat stress response of sheep (Ovis aries).
Neoplasms
The Role of p38 and CK2 Protein Kinases in the Response of RAW 264.7 Macrophages to Lipopolysaccharide.
Neoplasms
The role of the molecular chaperone CCT in protein folding and mediation of cytoskeleton-associated processes: implications for cancer cell biology.
Neoplasms
The selective Hsp90 inhibitor BJ-B11 exhibits potent antitumor activity via induction of cell cycle arrest, apoptosis and autophagy in Eca-109 human esophageal squamous carcinoma cells.
Neoplasms
The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity.
Neoplasms
The short-term effects of electrosurgical ablation on proinflammatory mediator production by intervertebral disc cells in tissue culture.
Neoplasms
The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.
Neoplasms
The small heat shock protein HspB2 is a novel anti-apoptotic protein that inhibits apical caspase activation in the extrinsic apoptotic pathway.
Neoplasms
The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.
Neoplasms
The spectral properties of (-)-epigallocatechin 3-O-gallate (EGCG) fluorescence in different solvents: dependence on solvent polarity.
Neoplasms
The stress response: implications for the clinical development of hsp90 inhibitors.
Neoplasms
The targeted inhibition of Hsp90 by a synthetic small molecule, DPide offers an effective treatment strategy against TNBCs.
Neoplasms
The therapeutic implications of clinically applied modifiers of heat shock protein 70 (Hsp70) expression by tumor cells.
Neoplasms
The therapeutic properties of resminostat for hepatocellular carcinoma.
Neoplasms
The Therapeutic Target Hsp90 and Cancer Hallmarks.
Neoplasms
The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion.
Neoplasms
The transcriptomic responses of the ark shell, Anadara broughtonii, to sulfide and hypoxia exposure.
Neoplasms
The treatment and prevention of mouse melanoma with an oral DNA vaccine carried by attenuated Salmonella typhimurium.
Neoplasms
The tumor promoting roles of HSP60 and HIF2? in gastric cancer cells.
Neoplasms
The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis.
Neoplasms
The unfolded protein response regulator GRP78 is a novel predictive biomarker in colorectal cancer.
Neoplasms
The universe of Hsp90.
Neoplasms
The ups and downs of MEK kinase interactions.
Neoplasms
The use of hybrid phage displaying antigen epitope and recombinant protein in the diagnosis of systemic Candida albicans infection in rabbits and cancer patients.
Neoplasms
The use of matrix coating assisted by an electric field (MCAEF) to enhance mass spectrometric imaging of human prostate cancer biomarkers.
Neoplasms
The versatile stress protein mortalin as a chaperone therapeutic agent.
Neoplasms
Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion.
Neoplasms
Therapeutic and diagnostic implications of Hsp90 activation.
Neoplasms
Therapeutic cancer vaccines.
Neoplasms
Therapeutic effects of kaempferol affecting autophagy and endoplasmic reticulum stress.
Neoplasms
Therapeutic effects of radiolabeled 17-allylamino-17-demethoxygeldanamycin on human H460 nonsmall-cell lung carcinoma xenografts in mice.
Neoplasms
Therapeutic efficacy of tumor-derived heat shock protein 70 immunotherapy combining interleukin-2 on tumor-bearing mice.
Neoplasms
Therapeutic option for managing lung injury induced by infrarenal aortic cross-clamping.
Neoplasms
Therapeutic potency of heat-shock protein-90 pharmacological inhibitors in the treatment of gastrointestinal cancer, current status and perspectives.
Neoplasms
Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK.
Neoplasms
Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
Neoplasms
Therapeutic uses of HSP90 inhibitors in Non-Small Cell Lung Carcinoma (NSCLC).
Neoplasms
Thermal aggregates of human mortalin and Hsp70-1A behave as supramolecular assemblies.
Neoplasms
Thermally Responsive Nanoparticle-Encapsulated Curcumin and Its Combination with Mild Hyperthermia for Enhanced Cancer Cell Destruction.
Neoplasms
Thermosensitization, heat shock protein synthesis and development of thermotolerance in M-14 human tumor cells subjected to step-down heating.
Neoplasms
Thermotherapy using magnetic cationic liposomes powerfully suppresses prostate cancer bone metastasis in a novel rat model.
Neoplasms
Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala).
Neoplasms
Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.
Neoplasms
Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle.
Neoplasms
TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death.
Neoplasms
TNF-alpha, IL-1 alpha, IL-6 and ICAM-1 expression in human keratinocytes stimulated in vitro with Escherichia coli heat-shock proteins.
Neoplasms
To fold or not to fold: modulation and consequences of Hsp90 inhibition.
Neoplasms
Tomm34 is commonly expressed in epithelial ovarian cancer and associates with tumour type and high FIGO stage.
Neoplasms
Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23.
Neoplasms
Total flavonoids, extracted from Polygonum knotweed L, exert beneficial hepatoprotection against liver injury.
Neoplasms
Total synthesis of herbimycin A.
Neoplasms
Towards a better way to die with chemotherapy: role of heat shock protein exposure on dying tumor cells.
Neoplasms
Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes.
Neoplasms
Towards in-silico design of new HSP90 inhibitors: Molecular docking and 3D-QSAR CoMFA studies of tetrahydropyrido [4, 3-d] pyrimidine derivatives as HSP90 inhibitors.
Neoplasms
Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage.
Neoplasms
Transactivation of the epidermal growth factor receptor by heat shock protein 90 via Toll-like receptor 4 contributes to the migration of glioblastoma cells.
Neoplasms
Transcatheter arterial embolization combined with radiofrequency ablation activates CD8(+) T-cell infiltration surrounding residual tumors in the rabbit VX2 liver tumors.
Neoplasms
Transcription inhibition of heat shock proteins: a strategy for combination of 17-allylamino-17-demethoxygeldanamycin and actinomycin d.
Neoplasms
Transcriptional activation of heat shock protein 27 gene expression by 17beta-estradiol and modulation by antiestrogens and aryl hydrocarbon receptor agonists.
Neoplasms
Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.
Neoplasms
Transcriptional regulation of small HSP-HSF1 and beyond.
Neoplasms
Transcriptional upregulation of HSP70-2 by HIF-1 in cancer cells in response to hypoxia.
Neoplasms
Transcriptome analysis of human Leydig cell tumours reveals potential mechanisms underlying its development.
Neoplasms
Transcriptomic analysis of the effect of ifosfamide on MDCK cells cultivated in microfluidic biochips.
Neoplasms
Transcriptomic analysis reveals that heat shock protein 90? is a potential diagnostic and prognostic biomarker for cancer.
Neoplasms
Transcriptomic and proteomic approach to studying SNX-2112-induced K562 cells apoptosis and anti-leukemia activity in K562-NOD/SCID mice.
Neoplasms
Transcriptomic and Proteomic Investigation of HSP90A as a Potential Biomarker for HCC.
Neoplasms
Transcriptomic characterization of fibrolamellar hepatocellular carcinoma.
Neoplasms
Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold.
Neoplasms
Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
Neoplasms
Translational Research to Improve the Efficacy of Carbon Ion Radiotherapy: Experience of Gunma University.
Neoplasms
Translational Shift of HSP90 as a Novel Therapeutic Target from Cancer to Neurodegenerative Disorders: an Emerging Trend in the Cure of Alzheimer's and Parkinson's diseases.
Neoplasms
Translationally controlled tumor protein is a novel heat shock protein with chaperone-like activity.
Neoplasms
Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells.
Neoplasms
TRAP-1, the mitochondrial Hsp90.
Neoplasms
TRAP1 controls cell cycle G2-M transition through the regulation of CDK1 and MAD2 expression/ubiquitination.
Neoplasms
TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways.
Neoplasms
TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial-mesenchymal transition.
Neoplasms
TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors.
Neoplasms
TRAP1 Provides Protection Against Myocardial Ischemia-Reperfusion Injury by Ameliorating Mitochondrial Dysfunction.
Neoplasms
TRAP1 regulates autophagy in lung cancer cells.
Neoplasms
TRAP1 regulates cell cycle and apoptosis in thyroid carcinoma cells.
Neoplasms
TRAP1 Regulates Proliferation, Mitochondrial Function and has Prognostic Significance in NSCLC.
Neoplasms
TRAP1 Regulation of Cancer Metabolism: Dual Role as Oncogene or Tumor Suppressor.
Neoplasms
TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 inhibitors.
Neoplasms
TRAP1 revisited: novel localizations and functions of a 'next-generation' biomarker (review).
Neoplasms
TRAP1 shows clinical significance and promotes cellular migration and invasion through STAT3/MMP2 pathway in human esophageal squamous cell cancer.
Neoplasms
Treatment of ras-induced cancers by the F-actin-bundling drug MKT-077.
Neoplasms
Trefoil factor 1 (TFF1/pS2) deficiency activates the unfolded protein response.
Neoplasms
Trends in the early investigational drug development and areas for improvement.
Neoplasms
Triazole Containing Novobiocin and Biphenyl Amides as Hsp90 C-Terminal Inhibitors.
Neoplasms
Triggering senescence programs suppresses Chk1 kinase and sensitizes cells to genotoxic stresses.
Neoplasms
Triptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation.
Neoplasms
Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo.
Neoplasms
Tuberous sclerosis complex protein 1 expression is affected by VHL Gene alterations and HIF-1? production in sporadic clear-cell renal cell carcinoma.
Neoplasms
Tubocapsenolide A targets C-terminal cysteine residues of HSP90 to exert the anti-tumor effect.
Neoplasms
Tumor antigen delivered by Salmonella III secretion protein fused with heat shock protein 70 induces protection and eradication against murine melanoma.
Neoplasms
Tumor cell expression of heat shock protein (HSP) 72 is influenced by HSP72 [HSPA1B A(1267)G] polymorphism and predicts survival in small Cell lung cancer (SCLC) patients.
Neoplasms
Tumor cell membrane-bound heat shock protein 70 elicits antitumor immunity.
Neoplasms
Tumor Cell Surface Display of Immunoglobulin Heavy Chain Fc by Gene Transfer as a Means to Mimic Antibody Therapy.
Neoplasms
Tumor cell surface display of immunoglobulin heavy chain Fc by gene transfer as a means to mimic antibody therapy.
Neoplasms
Tumor heterogeneity, clonal evolution, and therapy resistance: an opportunity for multitargeting therapy.
Neoplasms
Tumor Immune Systems in Esophageal Cancer with Special Reference to Heat-shock Protein 70 and Humoral Immunity.
Neoplasms
Tumor immunity and prolonged survival following combined adenovirus-HSP72 and CEA-plasmid vaccination.
Neoplasms
Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression.
Neoplasms
Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90.
Neoplasms
Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation.
Neoplasms
Tumor necrosis factor induces the rapid phosphorylation of the mammalian heat shock protein hsp28.
Neoplasms
Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) Mutation and TRAP1 Inhibitor Gamitrinib-triphenylphosphonium (G-TPP) Induce a Forkhead Box O (FOXO)-dependent Cell Protective Signal from Mitochondria.
Neoplasms
Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases.
Neoplasms
Tumor necrosis factor-alpha and alphaB-crystallin up-regulation during antibody-mediated demyelination in vitro: a putative protective mechanism in oligodendrocytes.
Neoplasms
Tumor necrosis factor-alpha-induced expression of heat shock protein 72 in adult feline cardiac myocytes.
Neoplasms
Tumor prevention and antitumor immunity with heat shock protein 70 induced by 15-deoxy-delta12,14-prostaglandin J2 in transgenic adenocarcinoma of mouse prostate cells.
Neoplasms
Tumor response to mTHPC-mediated photodynamic therapy exhibits strong correlation with extracellular release of HSP70.
Neoplasms
Tumor secreted Hsp90 subverts Polycomb function to drive prostate tumor growth and invasion.
Neoplasms
Tumor selectivity of Hsp90 inhibitors: the explanation remains elusive.
Neoplasms
Tumor specific binding of radiolabeled PEGylated GIRLRG peptide; a novel agent for targeting cancers.
Neoplasms
Tumor suppression by apoptotic and anti-angiogenic effects of mortalin-targeting adeno-oncolytic virus.
Neoplasms
Tumor Suppression Efficacy of Heat Shock Protein 90 Inhibitor 17AAG in a Liposarcoma Mouse Model.
Neoplasms
Tumor suppressor function of Betaig-h3 gene in radiation carcinogenesis.
Neoplasms
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.
Neoplasms
Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Neoplasms
Tumor-derived heat shock protein 70-pulsed dendritic cells elicit tumor-specific cytotoxic T lymphocytes (CTLs) and tumor immunity.
Neoplasms
Tumor-derived, chaperone-rich cell lysate activates dendritic cells and elicits potent antitumor immunity.
Neoplasms
Tumor-induced angiogenesis studied in confrontation cultures of multicellular tumor spheroids and embryoid bodies grown from pluripotent embryonic stem cells.
Neoplasms
Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90-Targeted Therapy.
Neoplasms
Tumor-Microenvironment-Responsive Nanoconjugate for Synergistic Antivascular Activity and Phototherapy.
Neoplasms
Tumor-released autophagosomes induces CD4+ T cell-mediated immunosuppression via a TLR2-IL-6 cascade.
Neoplasms
Tumor-secreted GRP78 facilitates the migration of macrophages into tumors by promoting cytoskeleton remodeling.
Neoplasms
Tumor-Secreted GRP78 Promotes the Establishment of a Pre-metastatic Niche in the Liver Microenvironment.
Neoplasms
Tumor-suppressive effect of a telomerase-derived peptide by inhibiting hypoxia-induced HIF-1?-VEGF signaling axis.
Neoplasms
Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.
Neoplasms
Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA.
Neoplasms
Tumour cell expression of interleukin 6 receptor ? is associated with response rates in patients treated with sunitinib for metastatic clear cell renal cell carcinoma.
Neoplasms
Tumour eradication using synchronous thermal ablation and Hsp90 chemotherapy with protein engineered triblock biopolymer-geldanamycin conjugates.
Neoplasms
Tumour necrosis factor-alpha production stimulated by heat shock protein 70 and its inhibition in circulating dendritic cells and cells eluted from mucosal tissues in Crohn's disease.
Neoplasms
Tumour progression: random mutations or an integrated survival response to cellular stress conserved from unicellular organisms?
Neoplasms
Tumour rejection antigens of the hsp90 family (gp96) closely resemble tumour-associated heparanase enzymes.
Neoplasms
Tunicamycin-induced ER stress in breast cancer cells neither expresses GRP78 on the surface nor secretes it into the media.
Neoplasms
Two-dimensional gel analysis of protein expression profile in squamous cervical cancer patients.
Neoplasms
Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells.
Neoplasms
UBR1 promotes protein kinase quality control and sensitizes cells to Hsp90 inhibition.
Neoplasms
UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.
Neoplasms
Ultrafast Low-Temperature Photothermal Therapy Activates Autophagy and Recovers Immunity for Efficient Antitumor Treatment.
Neoplasms
Ultrasensitive analysis of heat shock protein 90? with antibodies orderly arrayed on a novel type of immunoprobe based on magnetic COFs.
Neoplasms
Ultrasound irradiation inhibits proliferation of cervical cancer cells by initiating endoplasmic reticulum stress-mediated apoptosis and triggering phosphorylation of JNK.
Neoplasms
Ultrasound Targeted Microbubble Destruction for Novel Dual Targeting of HSP72 and HSC70 in Prostate Cancer.
Neoplasms
Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma.
Neoplasms
Uncovering biosynthetic potential of plant-associated fungi: effect of culture conditions on metabolite production by Paraphaeosphaeria quadriseptata and Chaetomium chiversii.
Neoplasms
Understanding conformational diversity of heat shock protein 90 (HSP90) and binding features of inhibitors to HSP90 via molecular dynamics simulations.
Neoplasms
Understanding the Hsp90 N-terminal Dynamics: Structural and Molecular Insights into the Therapeutic Activities of Anticancer Inhibitors Radicicol (RD) and Radicicol Derivative (NVP-YUA922).
Neoplasms
Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness.
Neoplasms
Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments.
Neoplasms
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1.
Neoplasms
Untangling the unfolded protein response.
Neoplasms
Unusual expression and localization of heat-shock proteins in human tumor cells.
Neoplasms
Unusual Suspects in the Twilight Zone Between the Hsp90 Interactome and Carcinogenesis.
Neoplasms
Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells.
Neoplasms
Up-regulation of heat shock protein 70 in adenocarcinomas of the lung in smokers.
Neoplasms
Update on Hsp90 Inhibitors in Clinical Trial.
Neoplasms
Update on immunotherapy for melanoma.
Neoplasms
Upon oxidative stress, the antiapoptotic Hsp60/procaspase-3 complex persists in mucoepidermoid carcinoma cells.
Neoplasms
Upregulated Heat Shock Proteins After Hyperthermic Chemotherapy Point to Induced Cell Survival Mechanisms in Affected Tumor Cells From Peritoneal Carcinomatosis.
Neoplasms
Upregulated HSPA2 predicts early relapse of pancreatic cancer after surgery.
Neoplasms
Upregulation of collagenase-1 and -3 in indomethacin-induced gastric ulcer in diabetic rats: role of melatonin.
Neoplasms
Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.
Neoplasms
Upregulation of GRP78 in Renal Cell Carcinoma and Its Significance.
Neoplasms
Upregulation of heat shock protein 70 and the differential protein expression induced by tumor necrosis factor-alpha enhances migration and inhibits apoptosis of hepatocellular carcinoma cell HepG2.
Neoplasms
Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular carcinoma.
Neoplasms
Upregulation of heat shock protein 27 confers resistance to actinomycin D-induced apoptosis in cancer cells.
Neoplasms
Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis.
Neoplasms
Upstream sequences required for efficient expression of a soybean heat shock gene.
Neoplasms
Use of autoantibodies against tumor-associated antigens as serum biomarkers for primary screening of cervical cancer.
Neoplasms
Use of in vivo bioluminescence and MRI to determine hyperthermia-induced changes in luciferase activity under the control of an hsp70 promoter.
Neoplasms
Use of protein-based biomarkers of exfoliated cervical cells for primary screening of cervical cancer.
Neoplasms
Use of the glucose starvation-inducible glucose-regulated protein 78 promoter in suicide gene therapy of murine fibrosarcoma.
Neoplasms
Using natural product inhibitors to validate Hsp90 as a molecular target in cancer.
Neoplasms
Utilizing integrating network pharmacological approaches to investigate the potential mechanism of Ma Xing Shi Gan Decoction in treating COVID-19.
Neoplasms
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors.
Neoplasms
Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings.
Neoplasms
Vaccination with B16 tumor cell lysate plus recombinant Mycobacterium tuberculosis Hsp70 induces antimelanoma effect in mice.
Neoplasms
Vaccination with TCL plus MHSP65 induces anti-lung cancer immunity in mice.
Neoplasms
Vaginal nitric oxide in pregnant women with bacterial vaginosis.
Neoplasms
Validation of heat shock protein 70 as a tumor-specific biomarker for monitoring the outcome of radiation therapy in tumor mouse models.
Neoplasms
Validation of the Hsp70-Bag3 Protein-Protein Interaction as a Potential Therapeutic Target in Cancer.
Neoplasms
Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations.
Neoplasms
Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci.
Neoplasms
Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment.
Neoplasms
Vaspin Is an Adipokine Ameliorating ER Stress in Obesity as a Ligand for Cell-Surface GRP78/MTJ-1 Complex.
Neoplasms
Vincristine ablation of Sirt2 induces cell apoptosis and mitophagy via Hsp70 acetylation in MDA-MB-231 cells.
Neoplasms
Virtual prototyping study shows increased ATPase activity of Hsp90 to be the key determinant of cancer phenotype.
Neoplasms
Virtual screening and biophysical studies lead to HSP90 inhibitors.
Neoplasms
Virtual screening based identification of miltefosine and octenidine as inhibitors of heat shock protein 90.
Neoplasms
Visceral regeneration in a sea cucumber involves extensive expression of survivin and mortalin homologs in the mesothelium.
Neoplasms
Visualizing and Quantifying the Effect of the Inhibition of HSP70 on Breast Cancer Cells Based on Laser Scanning Microscopy.
Neoplasms
Vitespen: a preclinical and clinical review.
Neoplasms
Volume of Hsp90 Protein-Ligand Binding Determined by Fluorescent Pressure Shift Assay, Densitometry, and NMR.
Neoplasms
Water amino acid-chelated trace mineral supplementation decreases circulating and intestinal HSP70 and proinflammatory cytokine gene expression in heat-stressed broiler chickens.
Neoplasms
What we know about ST13, a co-factor of heat shock protein, or a tumor suppressor?
Neoplasms
Wild-type EGFR Is Stabilized by Direct Interaction with HSP90 in Cancer Cells and Tumors.
Neoplasms
Withaferin A targets heat shock protein 90 in pancreatic cancer cells.
Neoplasms
Withania somnifera Suppresses Tumor Growth of Intracranial Allograft of Glioma Cells.
Neoplasms
Withanolides-induced breast cancer cell death is correlated with their ability to inhibit heat protein 90.
Neoplasms
Withanone binds to mortalin and abrogates mortalin-p53 complex: Computational and experimental evidence.
Neoplasms
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism.
Neoplasms
Words of wisdom. Re: Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Neoplasms
X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition.
Neoplasms
X66, a novel N-terminal heat shock protein 90 inhibitor, exerts antitumor effects without induction of heat shock response.
Neoplasms
Y-632 inhibits Hsp90 function through disrupting the interaction of Hsp90-Hop and exerts antitumor activity in vitro and in vivo.
Neoplasms
Zika virus envelope - heat shock protein A5 (GRP78) binding site prediction.
Neoplasms
[2 + 2 + 2] Cyclotrimerization with Propargyl Halides as Copartners: Formal Total Synthesis of the Antitumor Hsp90 Inhibitor AT13387.
Neoplasms
[Allogeneic dendritic cell vaccine pulsed with heat shocked tumor cell lysate can enhance antitumor immunity]
Neoplasms
[Association of occupational chronic psychological stress with heat shock protein 70 in serum and tumor necrosis factor-alpha expression levels].
Neoplasms
[Biology behavior of head and neck squamous cell cancer cells changes after knocking down heat shock protein 27].
Neoplasms
[Correlation of heat shock protein 70 expression in nasopharyngeal carcinoma to immunoglobin A against viral capsid antigen of Epstein-Barr virus in sera and its clinical significance]
Neoplasms
[Development of myeloproliferative neoplasms by mutant calreticulin: underlying mechanisms].
Neoplasms
[Diagnostic and Therapeutic Potential of Membrane HSP90].
Neoplasms
[Differential expression of secretagogin and glucose-related protein 78 in colorectal carcinoma: a proteome study]
Neoplasms
[Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung Adenocarcinoma.]
Neoplasms
[Effect of heat shock protein 90 inhibitor 17-dimethylamino-ethylaminogeldanamycin on TNfalpha-mediated apoptosis and TNF-induced NF-kappaB activation].
Neoplasms
[Effect of ketamine on endotoxin-induced septic shock in rats and its mechanism]
Neoplasms
[Effects of ascites derived exosomes on the stemness and invasion ability of ovarian cancer stem-like cell].
Neoplasms
[Effects of centimeter waves on the immune system of mice in endotoxic shock]
Neoplasms
[Effects of HMGB1 inhibition on endoplasmic reticulum stress after myocardial ischemia/reperfusion injury in rats].
Neoplasms
[Effects of HSP90 inhibitor 17-AAG on cell cycle and apoptosis of human gastric cancer cell lines SGC-7901].
Neoplasms
[Effects of pre-heating on the sensitivity of K562 cell to tumor necrosis factor-alpha]
Neoplasms
[Endoplasmic Reticulum Chaperones at the Tumor Cell Surface and in the Extracellular Space].
Neoplasms
[Expression and significance of heat shock protein 70, 90 in endometrial carcinomas]
Neoplasms
[Expression of heat shock protein 90 alpha and its effect on the growth of tumor in mice]
Neoplasms
[Expression of heat shock proteins in salivary gland tumors. Immunohistochemical study of HSP27, HSP70, HSP90, and HSP110: apropos of 50 cases]
Neoplasms
[Expression of HSP70 and P-glycoprotein (P-gp) in human hepatocarcinoma HepG2 cells induced by heat shock and inhibiting effect of quercetin on them]
Neoplasms
[Expression of P53 and heat shock protein in colorectal tumors: an immunohistochemical study]
Neoplasms
[Expressions of heat shock protein (HSP) family HSP 60, 70 and 90alpha in colorectal cancer tissues and their correlations to pathohistological characteristics.]
Neoplasms
[Ginsenoside Rh?-induced inhibition of histone deacetylase 6 promotes K562 cells autophagy and apoptosis in vivo].
Neoplasms
[Glucose regulated protein 78 kD]
Neoplasms
[Heat sensitivity of human cancer cells and abnormal expression of heat shock protein 70]
Neoplasms
[Heat shock protein 70 binding protein 1 induces enhanced apoptotic response against anticancer drugs in tumor cells]
Neoplasms
[Heat shock protein 70 induction by heat stress suppress interleukin-1beta and tumor necrosis factor-alpha levels in the brain tissue in rats with infectious brain edema]
Neoplasms
[Heat shock protein 70: an important survival factor for cancer cells]
Neoplasms
[Heat shock protein 90--modulator of TNFalpha-induced apoptosis of Jurkat tumor cells].
Neoplasms
[Heat shock protein 90: novel target for cancer therapy]
Neoplasms
[Heat shock proteins and malignancies of the female genital tract]
Neoplasms
[Heat shock proteins: new target in cytoprotective and tumor therapy]
Neoplasms
[Hsp70-H22 tumor antigen peptide complex activated dendritic cell in the induction of antitumor immunity]
Neoplasms
[Hsp90--a target for anticancer therapy].
Neoplasms
[Hsp90AB1 Protein is Overexpressed in Non-small Cell Lung Cancer Tissues ?and Associated with Poor Prognosis in Lung Adenocarcinoma Patients].
Neoplasms
[Immune activity of heat shock protein gp96 and its application in active immunotherapy for tumor and infectious diseases].
Neoplasms
[Immunocorrective effect of low intensity radiation of ultrahigh frequency on carcinogenesis in mice]
Neoplasms
[Impact of HSP90 Inhibition on Viability and Cell Cycle in Relation to p53 Status].
Neoplasms
[Inhibitors of the heat shock protein 90 activity: a novel class of tumor radiosensitizers].
Neoplasms
[Large-scale in vitro preparation of new gp96 tumor vaccine and analysis of its induction of specific anti-tumor immunoresponses].
Neoplasms
[Levels of cytokines and heat-shock protein 70 in the seminal plasma of patients with chronic bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome].
Neoplasms
[Mechanism of TTF1-NP induced implanted hepatoma tumor apoptosis in nude mice by endoplasmic reticulum stress pathway].
Neoplasms
[Mechanisms of the drug resistance of a 2', 2-difluorodeoxycytide (gemcitabine)-resistant variant of the human lung adenocarcinoma cell line]
Neoplasms
[Mitochondria HSP90: the target to inactivate in cancer therapy?]
Neoplasms
[Molecular chaperone HSP90 as a novel target for cancer chemotherapy]
Neoplasms
[Overexpression of heat shock protein 70 and spontaneous cancer cell apoptosis in hepatocellular carcinoma]
Neoplasms
[Pancreatic acinar neoplasms : Comparative molecular characterization].
Neoplasms
[Parallelism and paradoxes on viability and the life span of two loss-of-function mutations: heat shock protein transcriptional regulator hsf(1) and l(2)gl tumor suppressor in D. melanogaster].
Neoplasms
[Preliminary study on the antitumor immuno-protective mechanism of beta-elemene]
Neoplasms
[Progress in molecular chaperones participating in regulations of plant and animal development and evolution]
Neoplasms
[Progress in the study of heat shock protein 90 inhibitors]
Neoplasms
[Progress in the study of small molecule inhibitors of HSP90].
Neoplasms
[Relationship between chemosensitivity in vitro and the expression of GRP78 in non-small cell lung cancer.]
Neoplasms
[RNA Interference targeting GRP75 decreases cisplatin resistance in human lung adenocarcinoma cell].
Neoplasms
[Role and mechanism of cAMP/Ca 2+ signal pathway in differentiation of bone marrow mesenchymal stem cells into neuronal cells induced by salidroside].
Neoplasms
[Role of heat shock protein-peptide complexes on tumor and infectious diseases immunity]
Neoplasms
[Screening of citrullinated proteins in ten tumor cell lines].
Neoplasms
[Steroid hormonal receptors, heat shock protein and p53 of endometrioid and clear cell cancers in different localization]
Neoplasms
[The correlation between the up-regulation of Hsp90 and drug resistance to cisplatin in lung cancer cell line].
Neoplasms
[The protective effect of heat shock protein 72 by Doxorubicin in cold ischemia-reperfusion injury of the rat liver]
Neoplasms
[The Role of Membrane-Bound Heat Shock Proteins Hsp90 in Migration of Tumor Cells in vitro and Involvement of Cell Surface Heparan Sulfate Proteoglycans in Protein Binding to Plasma Membrane].
Neoplasms
[The role of the heat shock protein in human breast cancer]
Neoplasms
[Thermosensitization of tumor cells with inhibitors of chaperone activity and expression].
Neoplasms
[Tumor rejection antigen and cancer immunotherapy]
Neoplasms, Germ Cell and Embryonal
Testis cancer.
Neoplasms, Glandular and Epithelial
Expression and localization of GRP75 in human epithelial tumors and normal tissues.
Neoplasms, Neuroepithelial
Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis.
Neoplasms, Plasma Cell
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Neoplasms, Squamous Cell
Erratum to: Novel C-terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents.
Neoplasms, Squamous Cell
Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.
Neoplasms, Squamous Cell
Novel C-Terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents.
Neoplasms, Squamous Cell
Silencing heat shock protein 27 decreases metastatic behavior of human head and neck squamous cell cancer cells in vitro.
Neoplasms, Squamous Cell
[Biology behavior of head and neck squamous cell cancer cells changes after knocking down heat shock protein 27].
Neoplastic Processes
Identification of molecular candidates and interaction networks via integrative toxicogenomic analysis in a human cell line following low-dose exposure to the carcinogenic metals cadmium and nickel.
Nephritis
Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal.
Nephritis
Heat shock protein 70-2 and tumor necrosis factor-? gene polymorphisms in Chinese children with Henoch-Schönlein purpura.
Nephritis, Interstitial
T cells reactive to an inducible heat shock protein induce disease in toxin-induced interstitial nephritis.
Nephrosis, Lipoid
Renal tubular expression of Toll-like receptor 4 in cyclosporine nephrotoxicity.
Nephrotic Syndrome
Abnormal expression and distribution of heat shock protein 90: potential etiologic immunoendocrine mechanism of glucocorticoid resistance in idiopathic nephrotic syndrome.
Nephrotic Syndrome
Altered expression of glomerular heat shock protein 27 in experimental nephrotic syndrome.
Nephrotic Syndrome
Differential induction of podocyte heat shock proteins by prolonged single and combination toxic metal exposure.
Nephrotic Syndrome
HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II.
Nephrotic Syndrome
Nuclear HSP90 regulates the glucocorticoid responsiveness of PBMCs in patients with idiopathic nephrotic syndrome.
Nephrotic Syndrome
Renal tubular expression of Toll-like receptor 4 in cyclosporine nephrotoxicity.
Nerve Sheath Neoplasms
Immunohistochemical Evaluation of Heat Shock Protein Expression in Normal Canine Nerve and Peripheral Nerve Sheath Tumours.
Nervous System Diseases
Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention.
Nervous System Diseases
Expression of the human groEL stress-protein homologue in the brain and spinal cord.
Nervous System Diseases
First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90.
Nervous System Diseases
Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice.
Nervous System Diseases
Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders.
Nervous System Diseases
Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease.
Nervous System Diseases
Hsp60 response in experimental and human temporal lobe epilepsy.
Nervous System Diseases
Human TorsinA can function in the yeast cytosol as a molecular chaperone.
Nervous System Diseases
Role of glucose-regulated Protein 78 in embryonic development and neurological disorders.
Nervous System Diseases
[Glucose regulated protein 78 kD]
Neural Tube Defects
Heat shock proteins Hsp70-1 and Hsp70-3 Are necessary and sufficient to prevent arsenite-induced dysmorphology in mouse embryos.
Neural Tube Defects
Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.
Neural Tube Defects
In vitro analysis of the murine heat shock response: implications for reproductive toxicology.
Neuralgia
Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats.
Neuralgia
Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain.
Neurilemmoma
Binding partners for curcumin in human schwannoma cells: biologic implications.
Neurilemmoma
Elevated levels of mortalin expression in human brain tumors.
Neurilemmoma
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Neurilemmoma
Schwann cell autophagy induced by SAHA, 17-AAG, or clonazepam can reduce bortezomib-induced peripheral neuropathy.
Neuritis
Toll-like receptor-2, CD14 and heat-shock protein 70 in inflammatory lesions of rat experimental autoimmune neuritis.
Neuritis, Autoimmune, Experimental
Toll-like receptor-2, CD14 and heat-shock protein 70 in inflammatory lesions of rat experimental autoimmune neuritis.
Neuroblastoma
17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells.
Neuroblastoma
A Novel Mechanism of 17-AAG Therapeutic Efficacy on HSP90 Inhibition in MYCN-Amplified Neuroblastoma Cells.
Neuroblastoma
A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma.
Neuroblastoma
Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro.
Neuroblastoma
Biological Activity of a Thiobarbituric Acid Compound in Neuroblastomas.
Neuroblastoma
CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells.
Neuroblastoma
Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.
Neuroblastoma
Changes in heat shock protein 70 and ubiquitin mRNA levels in C1300 N2A mouse neuroblastoma cells following treatment with iron.
Neuroblastoma
Characterization of promoter elements mediating ethanol regulation of hsc70 gene transcription.
Neuroblastoma
Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines.
Neuroblastoma
Compromising the constitutive p16INK4a expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence.
Neuroblastoma
Curcumin Affects HSP60 Folding Activity and Levels in Neuroblastoma Cells.
Neuroblastoma
Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
Neuroblastoma
Does ORP150/HSP12A protect dopaminergic neurons against MPTP/MPP(+)-induced neurotoxicity?
Neuroblastoma
Down modulation of N-myc, heat-shock protein 70, and nucleolin during the differentiation of human neuroblastoma cells.
Neuroblastoma
Downregulation of DNAJC10 (ERDJ5) is associated with poor survival in breast cancer.
Neuroblastoma
Downregulation of miRNA-134 protects neural cells against ischemic injury in N2A cells and mouse brain with ischemic stroke by targeting HSPA12B.
Neuroblastoma
Dynamic Interaction of USP14 with the Chaperone HSC70 Mediates Crosstalk between the Proteasome, ER Signaling, and Autophagy.
Neuroblastoma
Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans.
Neuroblastoma
Effect of heat shock on intracellular calcium mobilization in neuroblastoma x glioma hybrid cells.
Neuroblastoma
Effect of let-7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinoma.
Neuroblastoma
Effects of alcohol on gene expression in neural cells.
Neuroblastoma
Effects of celastrol on Tau hyperphosphorylation and expression of HSF-1 and HSP70 in SH-SY5Y neuroblastoma cells induced by amyloid-? peptides.
Neuroblastoma
Effects of Hsp90 inhibition in neuroblastoma: analysis of drug sensitivity, target modulation and the influence of bone marrow microenvironment.
Neuroblastoma
Ethanol promotes endoplasmic reticulum stress-induced neuronal death: involvement of oxidative stress.
Neuroblastoma
Ethanol-responsive genes in neural cells include the 78-kilodalton glucose-regulated protein (GRP78) and 94-kilodalton glucose-regulated protein (GRP94) molecular chaperones.
Neuroblastoma
Exogenous heat shock protein HSP70 reduces response of human neuroblastoma cells to lipopolysaccharide.
Neuroblastoma
Expression of heat shock protein 90 at the cell surface in human neuroblastoma cells.
Neuroblastoma
Expression patterns of Trk-A, Trk-B, GRP78, and p75NRT in olfactory neuroblastoma.
Neuroblastoma
GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastic tumors.
Neuroblastoma
H9724, a monoclonal antibody to Borrelia burgdorferi's flagellin, binds to heat shock protein 60 (HSP60) within live neuroblastoma cells: a potential role for HSP60 in peptide hormone signaling and in an autoimmune pathogenesis of the neuropathy of Lyme disease.
Neuroblastoma
Heat shock protein 104 inhibited the fibrillization of prion peptide 106-126 and disassembled prion peptide 106-126 fibrils in vitro.
Neuroblastoma
Heat shock protein 70 induction by glutamine increases the ?-synuclein degradation in SH-SY5Y neuroblastoma cells.
Neuroblastoma
Heat shock protein 70 modulates neural progenitor cells dynamics in human neuroblastoma SH-SY5Y cells exposed to high glucose content.
Neuroblastoma
Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells.
Neuroblastoma
High Glucose Content Abrogated the Normal Activity of Heat Shock Protein Signaling Pathway in Human Neuroblastoma Cells.
Neuroblastoma
Histone deacetylase 10 promotes autophagy-mediated cell survival.
Neuroblastoma
HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation.
Neuroblastoma
Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma.
Neuroblastoma
Hsp90 inhibitors deplete key anti-apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin.
Neuroblastoma
Hsp90-mediated inhibition of FKBP38 regulates apoptosis in neuroblastoma cells.
Neuroblastoma
HSPA8 knock-down induces the accumulation of neurodegenerative disorder-associated proteins.
Neuroblastoma
Hyperbaric oxygen enhances the expression of prion protein and heat shock protein 70 in a mouse neuroblastoma cell line.
Neuroblastoma
Hypoglycemia enhances the expression of prion protein and heat-shock protein 70 in a mouse neuroblastoma cell line.
Neuroblastoma
Identification of GRP75 as an independent favorable prognostic marker of neuroblastoma by a proteomics analysis.
Neuroblastoma
Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506.
Neuroblastoma
Indolyl- and Pyrrolylazine Derivatives Cause the Accumulation of Heat Shock Protein Hsp70 in Sh-Sy5Y Human Neuroblastoma Cells.
Neuroblastoma
Inhibition of neuroblastoma xenograft growth by Hsp90 inhibitors.
Neuroblastoma
Interaction of ethanol with inducers of glucose-regulated stress proteins. Ethanol potentiates inducers of grp78 transcription.
Neuroblastoma
Localization and quantitation of hsp84 in mammalian cells.
Neuroblastoma
Mechanisms of neuronal adaptation to ethanol. Ethanol induces Hsc70 gene transcription in NG108-15 neuroblastoma x glioma cells.
Neuroblastoma
Methylation-associated silencing of the heat shock protein 47 gene in human neuroblastoma.
Neuroblastoma
Multiple protein kinases determine the phosphorylated state of the small heat shock protein, HSP27, in SH-SY5Y neuroblastoma cells.
Neuroblastoma
Neural differentiation and the attenuated heat shock response.
Neuroblastoma
Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.
Neuroblastoma
Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma.
Neuroblastoma
Nuclear translocation and aggregate formation of heat shock cognate protein 70 (Hsc70) in oxidative stress and apoptosis.
Neuroblastoma
Oxygen free radicals as inducers of heat shock protein synthesis in cultured human neuroblastoma cells: relevance to neurodegenerative disease.
Neuroblastoma
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
Neuroblastoma
Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells.
Neuroblastoma
Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis: An increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress.
Neuroblastoma
Proteomic Analysis on Anti-Proliferative and Apoptosis Effects of Curcumin Analog, 1,5-bis(4-Hydroxy-3-Methyoxyphenyl)-1,4-Pentadiene-3-One-Treated Human Glioblastoma and Neuroblastoma Cells.
Neuroblastoma
Proteomic identification of heat shock protein 27 as a differentiation and prognostic marker in neuroblastoma but not in Ewing's sarcoma.
Neuroblastoma
Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells.
Neuroblastoma
Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease.
Neuroblastoma
Rotenone Upregulates Alpha-Synuclein and Myocyte Enhancer Factor 2D Independently from Lysosomal Degradation Inhibition.
Neuroblastoma
SPARC overexpression suppresses radiation-induced HSP27 and induces the collapse of mitochondrial ?? in neuroblastoma cells.
Neuroblastoma
The basal flux of Akt in the mitochondria is mediated by heat shock protein 90.
Neuroblastoma
The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells.
Neuroblastoma
The protective role of HSP90 against 3-hydroxykynurenine-induced neuronal apoptosis.
Neuroblastoma
The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor.
Neuroblastoma
The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice.
Neuroblastoma
The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60.
Neuroblastoma
Thiopental protects human neuroblastoma cells from apoptotic cell death - Potential role of heat shock protein 70.
Neuroblastoma
Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells.
Neuroblastoma
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Neuroblastoma
[Effects of the Hydrogen Sulfide Donor GYY4137 and HSP70 Protein on the Activation of SH-SY5Y Cells by Lipopolysaccharide].
Neuroblastoma
[Exogenous HSP70 and Signaling Pathways Involved in the Inhibition of LPS-Induced Neurotoxicity of Neuroblastoma Cells].
Neuroblastoma
[Expression of heat-shock proteins in neuroblastoma cells differing genetically in thermal sensitivity]
Neuroblastoma
[Molecular chaperone Hsp70 protects neuroblastoma SK-N-SH cells from hypoxic stress]
Neuroblastoma
[The Effect of Beta-Amyloid Peptides and Main Stress Protein HSP70 on Human SH-SY5Y Neuroblastoma Proteome].
Neurocysticercosis
Taenia solium: characterization of a small heat shock protein (Tsol-sHSP35.6) and its possible relevance to the diagnosis and pathogenesis of neurocysticercosis.
Neurodegenerative Diseases
3-Arylcoumarin derivatives manifest anti-proliferative activity through Hsp90 inhibition.
Neurodegenerative Diseases
A cell model to study different degrees of Hsp60 deficiency in HEK293 cells.
Neurodegenerative Diseases
A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer's mouse model via an HSF1-mediated mechanism.
Neurodegenerative Diseases
A High-Throughput Screen for Inhibitors of the Hsp90-Chaperone Machine.
Neurodegenerative Diseases
A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T ?-Synuclein Toxicity.
Neurodegenerative Diseases
A role for astrocytes in cerebellar deficits in frataxin deficiency: Protection by insulin-like growth factor I.
Neurodegenerative Diseases
A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases.
Neurodegenerative Diseases
AAA+ Protein-Based Technologies to Counter Neurodegenerative Disease.
Neurodegenerative Diseases
Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2.
Neurodegenerative Diseases
Activation of PP2A-like phosphatase and modulation of tau phosphorylation accompany stress-induced apoptosis in cultured oligodendrocytes.
Neurodegenerative Diseases
Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).
Neurodegenerative Diseases
alphaB-crystallin (HspB5) in familial amyloidotic polyneuropathy.
Neurodegenerative Diseases
Approaches for defining the Hsp90-dependent proteome.
Neurodegenerative Diseases
Archaeal Unfoldase Counteracts Protein Misfolding Retinopathy in Mice.
Neurodegenerative Diseases
Augmentation of Bri2 molecular chaperone activity against amyloid-? reduces neurotoxicity in mouse hippocampus in vitro.
Neurodegenerative Diseases
Biological Evaluation of 5'-(N-Ethylcarboxamido)adenosine Analogues as Grp94-Selective Inhibitors.
Neurodegenerative Diseases
Brain Aging: Hsp90 and Neurodegenerative Diseases.
Neurodegenerative Diseases
Brain CHIP: removing the culprits in neurodegenerative disease.
Neurodegenerative Diseases
C-terminal amino acids are essential for human heat shock protein 70 dimerization.
Neurodegenerative Diseases
Characterization and Hsp104-induced artificial clearance of familial ALS-related SOD1 aggregates.
Neurodegenerative Diseases
Characterization of human small heat shock protein HspB1 that carries C-terminal domain mutations associated with hereditary motor neuron diseases.
Neurodegenerative Diseases
Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease.
Neurodegenerative Diseases
Combinational approach of intrabody with enhanced Hsp70 expression addresses multiple pathologies in a fly model of Huntington's disease.
Neurodegenerative Diseases
Correlation between chemotype-dependent binding conformations of HSP90?/? and isoform selectivity-Implications for the structure-based design of HSP90?/? selective inhibitors for treating neurodegenerative diseases.
Neurodegenerative Diseases
Covalent structural changes in unfolded GroES that lead to amyloid fibril formation detected by NMR: insight into intrinsically disordered proteins.
Neurodegenerative Diseases
Critical Role of Mortalin/GRP75 In Endothelial Cell Dysfunction Associated With Acute Lung Injury.
Neurodegenerative Diseases
Crystallins and neuroinflammation: The glial side of the story.
Neurodegenerative Diseases
Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13).
Neurodegenerative Diseases
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors.
Neurodegenerative Diseases
Development and application of Hsp90 inhibitors.
Neurodegenerative Diseases
Development of noviomimetics that modulate molecular chaperones and manifest neuroprotective effects.
Neurodegenerative Diseases
Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons.
Neurodegenerative Diseases
Discovery and development of purine-scaffold Hsp90 inhibitors.
Neurodegenerative Diseases
Disparate Mutations Confer Therapeutic Gain of Hsp104 Function.
Neurodegenerative Diseases
Drivers of Hsp104 potentiation revealed by scanning mutagenesis of the middle domain.
Neurodegenerative Diseases
Emerging novel concept of chaperone therapies for protein misfolding diseases.
Neurodegenerative Diseases
Engineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced Activity.
Neurodegenerative Diseases
Engineering therapeutic protein disaggregases.
Neurodegenerative Diseases
Exogenous Hsp70 delays senescence and improves cognitive function in aging mice.
Neurodegenerative Diseases
Expression of alphaB-crystallin in a mouse model of inherited retinal degeneration.
Neurodegenerative Diseases
Expression of one important chaperone protein, heat shock protein 27, in neurodegenerative diseases.
Neurodegenerative Diseases
Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro.
Neurodegenerative Diseases
Heat shock protein (hsx70) mRNA expression in human brain: effects of neurodegenerative disease and agonal state.
Neurodegenerative Diseases
Heat shock protein 27 in neuronal survival and neurite outgrowth.
Neurodegenerative Diseases
Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction.
Neurodegenerative Diseases
Heat shock protein 90 in neurodegenerative diseases.
Neurodegenerative Diseases
Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions.
Neurodegenerative Diseases
Heat shock protein 90: its inhibition and function.
Neurodegenerative Diseases
Heat shock protein 90: the cancer chaperone.
Neurodegenerative Diseases
Heat shock proteins and neuroprotection.
Neurodegenerative Diseases
Heat shock proteins at the crossroads between cancer and Alzheimer's disease.
Neurodegenerative Diseases
Heat shock proteins in neurodegenerative diseases: pathogenic roles and therapeutic implications.
Neurodegenerative Diseases
Heat shock proteins: a therapeutic target worth to consider.
Neurodegenerative Diseases
Herbimycins D-F, Ansamycin Analogues from Streptomyces sp. RM-7-15.
Neurodegenerative Diseases
High-throughput screening fluorescence polarization assay for tumor-specific hsp90.
Neurodegenerative Diseases
Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases.
Neurodegenerative Diseases
Hsp104: a weapon to combat diverse neurodegenerative disorders.
Neurodegenerative Diseases
Hsp60 and human aging: Les liaisons dangereuses.
Neurodegenerative Diseases
HSP70 and HSP90 in neurodegenerative diseases.
Neurodegenerative Diseases
Hsp70 participates in PINK1-mediated mitophagy by regulating the stability of PINK1.
Neurodegenerative Diseases
Hsp90 activity is necessary to acquire a proper neuronal polarization.
Neurodegenerative Diseases
Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases.
Neurodegenerative Diseases
Hsp90 chaperone inhibitor 17-AAG attenuates A?-induced synaptic toxicity and memory impairment.
Neurodegenerative Diseases
HSP90 inhibitor CH5164840 induces micronuclei in TK6 cells via an aneugenic mechanism.
Neurodegenerative Diseases
Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease.
Neurodegenerative Diseases
HSPA8 knock-down induces the accumulation of neurodegenerative disorder-associated proteins.
Neurodegenerative Diseases
HSPA9/Mortalin mediates axo-protection and modulates mitochondrial dynamics in neurons.
Neurodegenerative Diseases
HspB5/?B-crystallin phosphorylation at S45 and S59 is essential for protection of the dendritic tree of rat hippocampal neurons.
Neurodegenerative Diseases
Human Molecular Chaperone Hsp60 and Its Apical Domain Suppress Amyloid Fibril Formation of ?-Synuclein.
Neurodegenerative Diseases
Hydroximic Acid Derivatives: Pleiotrophic Hsp Co-Inducers Restoring Homeostasis and Robustness.
Neurodegenerative Diseases
Immobilization stress induces the expression of alphaB-crystallin in rat hippocampus: implications of glial activation in stress-mediated hippocampal degeneration.
Neurodegenerative Diseases
Indolyl- and Pyrrolylazine Derivatives Cause the Accumulation of Heat Shock Protein Hsp70 in Sh-Sy5Y Human Neuroblastoma Cells.
Neurodegenerative Diseases
Induction of heat shock proteins may combat insulin resistance.
Neurodegenerative Diseases
Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases.
Neurodegenerative Diseases
Inhibitors of heat shock protein 70 (Hsp70) with enhanced metabolic stability reduce tau levels.
Neurodegenerative Diseases
Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (A?42) aggregates leads to sub-stoichiometric inhibition of amyloid formation.
Neurodegenerative Diseases
Interactions between Hsp70 and the hydrophobic core of alpha-synuclein inhibit fibril assembly.
Neurodegenerative Diseases
Isolating potentiated Hsp104 variants using yeast proteinopathy models.
Neurodegenerative Diseases
Low endogenous and chemical induced heat shock protein induction in a 0N3Rtau-expressing Drosophila larval model of Alzheimer's disease.
Neurodegenerative Diseases
Mechanism of ER stress-induced brain damage by IP(3) receptor.
Neurodegenerative Diseases
Mechanistic Insights into Hsp104 Potentiation.
Neurodegenerative Diseases
Microglia activation triggers oligodendrocyte precursor cells apoptosis via HSP60.
Neurodegenerative Diseases
Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines.
Neurodegenerative Diseases
Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and ?-Synuclein Proteotoxicity.
Neurodegenerative Diseases
MitCHAP-60 and Hereditary Spastic Paraplegia SPG-13 Arise from an Inactive hsp60 Chaperonin that Fails to Fold the ATP Synthase ?-Subunit.
Neurodegenerative Diseases
Mitochondrial hsp60 chaperonopathy causes an autosomal-recessive neurodegenerative disorder linked to brain hypomyelination and leukodystrophy.
Neurodegenerative Diseases
Modified biphenyl Hsp90 C-terminal inhibitors for the treatment of cancer.
Neurodegenerative Diseases
Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein.
Neurodegenerative Diseases
Molecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin.
Neurodegenerative Diseases
Molecular Chaperone ERp29: A Potential Target for Cellular Protection in Retinal and Neurodegenerative Diseases.
Neurodegenerative Diseases
Molecular chaperones and neuronal proteostasis.
Neurodegenerative Diseases
Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects.
Neurodegenerative Diseases
Molecular Mechanisms Underlying Neuroprotective Effect of Intranasal Administration of Human Hsp70 in Mouse Model of Alzheimer's Disease.
Neurodegenerative Diseases
Mortalin is Expressed by Astrocytes and Decreased in the Midbrain of Parkinson's Disease Patients.
Neurodegenerative Diseases
Mortalin, apoptosis, and neurodegeneration.
Neurodegenerative Diseases
Mortalin - a multipotent chaperone regulating cellular processes ranging from viral infection to neurodegeneration.
Neurodegenerative Diseases
Natural product inhibitors of Hsp90: potential leads for drug discovery.
Neurodegenerative Diseases
Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line.
Neurodegenerative Diseases
Novel role of mortalin in attenuating HIV-1 Tat-mediated astrogliosis.
Neurodegenerative Diseases
Old and New Approaches to Target the Hsp90 Chaperone.
Neurodegenerative Diseases
Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins.
Neurodegenerative Diseases
Oxygen free radicals as inducers of heat shock protein synthesis in cultured human neuroblastoma cells: relevance to neurodegenerative disease.
Neurodegenerative Diseases
p97 Homologs from Caenorhabditis elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat.
Neurodegenerative Diseases
Pharmacologic and genetic inhibition of hsp90-dependent trafficking reduces aggregation and promotes degradation of the expanded glutamine androgen receptor without stress protein induction.
Neurodegenerative Diseases
Phenotyping of tianma-stimulated differentiated rat neuronal b104 cells by quantitative proteomics.
Neurodegenerative Diseases
Potential C-terminal-domain inhibitors of heat shock protein 90 derived from a C-terminal peptide helix.
Neurodegenerative Diseases
Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events.
Neurodegenerative Diseases
Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins.
Neurodegenerative Diseases
Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain.
Neurodegenerative Diseases
Protective effect of geranylgeranylacetone against hydrogen peroxide-induced oxidative stress in human neuroblastoma cells.
Neurodegenerative Diseases
Protective Effect of Tat PTD-Hsp27 Fusion Protein on Tau Hyperphosphorylation Induced by Okadaic Acid in the Human Neuroblastoma Cell Line SH-SY5Y.
Neurodegenerative Diseases
Protein-Remodeling Factors As Potential Therapeutics for Neurodegenerative Disease.
Neurodegenerative Diseases
Proteolytic stress causes heat shock protein induction, tau ubiquitination, and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture.
Neurodegenerative Diseases
Purification of hsp104, a protein disaggregase.
Neurodegenerative Diseases
Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity.
Neurodegenerative Diseases
Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.
Neurodegenerative Diseases
Resolution-Associated Molecular Patterns (RAMPs) as Endogenous Regulators of Glia Functions in Neuroinflammatory Disease.
Neurodegenerative Diseases
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
Neurodegenerative Diseases
Roles of molecular chaperones in the nervous system.
Neurodegenerative Diseases
SIRT1 Knockdown Promotes Neural Differentiation and Attenuates the Heat Shock Response.
Neurodegenerative Diseases
Small heat shock proteins, the cytoskeleton, and inclusion body formation.
Neurodegenerative Diseases
Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation.
Neurodegenerative Diseases
Stressing Out Hsp90 in Neurotoxic Proteinopathies.
Neurodegenerative Diseases
Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events.
Neurodegenerative Diseases
Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding.
Neurodegenerative Diseases
Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90.
Neurodegenerative Diseases
The chaperone Grp78 in protein folding disorders of the nervous system.
Neurodegenerative Diseases
The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules.
Neurodegenerative Diseases
The Hsp60 folding machinery is crucial for manganese superoxide dismutase folding and function.
Neurodegenerative Diseases
The HSP90 chaperone machinery.
Neurodegenerative Diseases
The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease.
Neurodegenerative Diseases
The Molecular Chaperone GRP78/BiP as a Therapeutic Target for Neurodegenerative Disorders: A Mini Review.
Neurodegenerative Diseases
The neuroprotective potential of heat shock protein 70 (HSP70).
Neurodegenerative Diseases
The Role of HSP70 and Its Co-chaperones in Protein Misfolding, Aggregation and Disease.
Neurodegenerative Diseases
The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.
Neurodegenerative Diseases
The stress response: implications for the clinical development of hsp90 inhibitors.
Neurodegenerative Diseases
Therapeutic genetic variation revealed in diverse Hsp104 homologs.
Neurodegenerative Diseases
Thermal aggregates of human mortalin and Hsp70-1A behave as supramolecular assemblies.
Neurodegenerative Diseases
To fold or not to fold: modulation and consequences of Hsp90 inhibition.
Neurodegenerative Diseases
Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics.
Neurodegenerative Diseases
Translational Shift of HSP90 as a Novel Therapeutic Target from Cancer to Neurodegenerative Disorders: an Emerging Trend in the Cure of Alzheimer's and Parkinson's diseases.
Neurodegenerative Diseases
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Neurodegenerative Diseases
[A molecular chaperone inducer as potential therapeutic agent for neurodegenerative disease]
Neuroectodermal Tumors
Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.
Neuroectodermal Tumors
Correlation between the progressive cytoplasmic expression of a novel small heat shock protein (Hsp16.2) and malignancy in brain tumors.
Neuroectodermal Tumors
Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57.
Neuroectodermal Tumors, Primitive
PI3K/Akt/mTOR pathway inhibitors in the therapy of pancreatic neuroendocrine tumors.
Neuroendocrine Tumors
177Lu-octreotate therapy for neuroendocrine tumours is enhanced by Hsp90 inhibition.
Neuroendocrine Tumors
18F-Radiolabeling and Preliminary Evaluation of a HSP90 ligand.
Neuroendocrine Tumors
Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets.
Neuroendocrine Tumors
Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors.
Neuroendocrine Tumors
HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.
Neuroendocrine Tumors
Neuroendocrine tumors of the gastrointestinal tract: recent advances in molecular genetics, diagnosis, and treatment.
Neuroendocrine Tumors
Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells.
Neuroendocrine Tumors
The HSP90 inhibitor onalespib potentiates 177Lu?DOTATATE therapy in neuroendocrine tumor cells.
Neurofibromatoses
Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2.
Neurofibromatosis 2
Combining curcumin (diferuloylmethane) and heat shock protein inhibition for neurofibromatosis 2 treatment: analysis of response and resistance pathways.
Neurofibromatosis 2
Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2.
Neurofibrosarcoma
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Neurofibrosarcoma
Targeting Refractory Sarcomas and Malignant Peripheral Nerve Sheath Tumors in a Phase I/II Study of Sirolimus in Combination with Ganetespib (SARC023).
Neuroinflammatory Diseases
?B-Crystallin regulates expansion of CD11b?Gr-1? immature myeloid cells during tumor progression.
Neuroinflammatory Diseases
Characterization of migration parameters on peripheral and central nervous system T cells following treatment of experimental allergic encephalomyelitis with CRYAB.
Neuroinflammatory Diseases
Current and emerging therapeutic targets for Parkinson's disease.
Neuroinflammatory Diseases
Heat shock protein 70 suppresses neuroinflammation induced by ?-synuclein in astrocytes.
Neuroinflammatory Diseases
Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition.
Neuroinflammatory Diseases
Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS.
Neuroinflammatory Diseases
Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte NF-?B/NLRP3 inflammasome pathway : HSPA8 inhibition protects spinal ischemia-reperfusion injury.
Neuroinflammatory Diseases
Luteolin alleviates cognitive impairment in Alzheimer's disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation.
Neuroinflammatory Diseases
Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity.
Neuroinflammatory Diseases
Mitogen-activated protein kinase-activated protein kinase 2 in neuroinflammation, heat shock protein 27 phosphorylation, and cell cycle: role and targeting.
Neuroinflammatory Diseases
Molecular chaperone alpha-crystallin prevents detrimental effects of neuroinflammation.
Neuroinflammatory Diseases
Novel role of mortalin in attenuating HIV-1 Tat-mediated astrogliosis.
Neuroinflammatory Diseases
Peripherally misfolded proteins exacerbate ischemic stroke-induced neuroinflammation and brain injury.
Neuroinflammatory Diseases
Role of Mitochondrial Stress Protein HSP60 in Diabetes-Induced Neuroinflammation.
Neuroinflammatory Diseases
Surgery-induced cognitive dysfunction is alleviated through triggering receptor expressed on myeloid cells 2.
Neuroinflammatory Diseases
The anti-inflammatory and antiapoptotic effects of probiotic on induced neurotoxicity in juvenile hamsters.
Neuroinflammatory Diseases
The impact of postsynaptic density 95 blocking peptide (Tat-NR2B9c) and an iNOS inhibitor (1400W) on proteomic profile of the hippocampus in C57BL/6J mouse model of kainate-induced epileptogenesis.
Neuroinflammatory Diseases
Therapeutic Intervention in Multiple Sclerosis with Alpha B-Crystallin: A Randomized Controlled Phase IIa Trial.
Neurologic Manifestations
Correlation of lymphocyte heat shock protein 70 levels with neurologic deficits in elderly patients with cerebral infarction.
Neuromuscular Diseases
Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases.
Neuromuscular Diseases
MitCHAP-60 and Hereditary Spastic Paraplegia SPG-13 Arise from an Inactive hsp60 Chaperonin that Fails to Fold the ATP Synthase ?-Subunit.
Neuromuscular Diseases
Novel insights in the disease biology of mutant small heat shock proteins in neuromuscular diseases.
Neuromuscular Diseases
Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.
Neuromyelitis Optica
GRP78 antibodies damage the blood-brain barrier and relate to cerebellar degeneration in Lambert-Eaton myasthenic syndrome.
Neuromyelitis Optica
GRP78 autoantibodies initiate the breakdown of the blood-brain barrier in neuromyelitis optica.
Neutropenia
Epidemiology, genetic variants and clinical course of natural infections with Anaplasma phagocytophilum in a dairy cattle herd.
Nevus
HSP90 as a marker of progression in melanoma.
Nevus
Prognostic implications of markers of the metabolic phenotype in human cutaneous melanoma.
Nevus, Pigmented
Expression of heat shock protein 105 and 70 in malignant melanoma and benign melanocytic nevi.
Nevus, Pigmented
Expression of the heat shock cognate protein HSP73 correlates with tumour thickness of primary melanomas and is enhanced in melanoma metastases.
Nevus, Pigmented
Induction of Hsp90 protein expression in malignant melanomas and melanoma metastases.
Newcastle Disease
Autophagy in farm animals: current knowledge and future challenges.
Niemann-Pick Disease, Type C
Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease.
Niemann-Pick Diseases
Relationship between HSP90a, NPC2 and L-PGDS proteins to boar semen freezability.
Nocardia Infections
Comparison of protective efficacy between two DNA vaccines encoding DnaK and GroEL against fish nocardiosis.
Non-alcoholic Fatty Liver Disease
Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study.
Non-alcoholic Fatty Liver Disease
Glucose regulated protein 78 is potentially an important player in the development of nonalcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
Heat Shock Protein 27 is down-regulated in Ballooned Hepatocytes of Patients with Nonalcoholic Steatohepatitis (NASH).
Non-alcoholic Fatty Liver Disease
Hsp90 modulates PPAR? activity in a mouse model of nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Investigating Molecular Connections of Non-alcoholic Fatty Liver Disease with Associated Pathological Conditions in West Virginia for Biomarker Analysis.
Non-alcoholic Fatty Liver Disease
Loss and gain of function of Grp75 or mitofusin 2 distinctly alter cholesterol metabolism, but all promote triglyceride accumulation in hepatocytes.
Non-alcoholic Fatty Liver Disease
Serum Fragmented Cytokeratin 18 Levels Reflect the Histologic Activity Score of Nonalcoholic Fatty Liver Disease More Accurately Than Serum Alanine Aminotransferase Levels.
Non-alcoholic Fatty Liver Disease
Silymarin attenuated nonalcoholic fatty liver disease through the regulation of endoplasmic reticulum stress proteins GRP78 and XBP-1 in mice.
Non-alcoholic Fatty Liver Disease
The ménage à trois of autophagy, lipid droplets and liver disease.
Non-alcoholic Fatty Liver Disease
[Effects of electroacupuncture combined with dietary control on liver endoplasmic reticulum stress in rats with non-alcoholic fatty liver disease].
non-chaperonin molecular chaperone atpase deficiency
A Cell Model for HSP60 Deficiencies: Modeling Different Levels of Chaperonopathies Leading to Oxidative Stress and Mitochondrial Dysfunction.
non-chaperonin molecular chaperone atpase deficiency
A cell model to study different degrees of Hsp60 deficiency in HEK293 cells.
non-chaperonin molecular chaperone atpase deficiency
A new case of multiple mitochondrial enzyme deficiencies with decreased amount of heat shock protein 60.
non-chaperonin molecular chaperone atpase deficiency
Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis.
non-chaperonin molecular chaperone atpase deficiency
Constitutive heat shock protein 70 interacts with ?-enolase and protects cardiomyocytes against oxidative stress.
non-chaperonin molecular chaperone atpase deficiency
Decreased synthesis and inefficient mitochondrial import of hsp60 in a patient with a mitochondrial encephalomyopathy.
non-chaperonin molecular chaperone atpase deficiency
GRP78 effectively protect hypoxia/reperfusion-induced myocardial apoptosis via promotion of the Nrf2/HO-1 signaling pathway.
non-chaperonin molecular chaperone atpase deficiency
Hsp104 disaggregase at normal levels cures many [PSI(+)] prion variants in a process promoted by Sti1p, Hsp90, and Sis1p.
non-chaperonin molecular chaperone atpase deficiency
Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis.
non-chaperonin molecular chaperone atpase deficiency
Molecular chaperone disorders: defective hsp60 in neurodegeneration.
non-chaperonin molecular chaperone atpase deficiency
Mortalin deficiency suppresses fibrosis and induces apoptosis in keloid spheroids.
non-chaperonin molecular chaperone atpase deficiency
Overexpression of Hsc70 promotes proliferation, migration, and invasion of human glioma cells.
non-chaperonin molecular chaperone atpase deficiency
[Mechanism of heat shock protein 90 for regulating 26S proteasome in hyperthermia].
Obesity
17-DMAG, an Hsp90 inhibitor, ameliorates ovariectomy-induced obesity in rats.
Obesity
Adipocytes from new zealand obese mice exhibit aberrant proinflammatory reactivity to the stress signal heat shock protein 60.
Obesity
An acylic polyisoprenoid derivative, geranylgeranylacetone protects against visceral adiposity and insulin resistance in high-fat-fed mice.
Obesity
Association of extracellular heat shock protein 70 and insulin resistance in type 2 diabetes; independent of obesity and C-reactive protein.
Obesity
Association of heat shock protein70-2 (HSP70-2) gene polymorphism with obesity.
Obesity
Autoimmunity to HSP60 during diet induced obesity in mice.
Obesity
Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice-a new potential probiotic for appetite and body weight management.
Obesity
Daily rhythm and heat shock protein expression in obese ob/ob mice.
Obesity
Effects of in vitro heat shock on immune cells in diet-induced obese mice.
Obesity
Endoplasmic reticulum chaperone GRP78 regulates macrophage function and insulin resistance in diet-induced obesity.
Obesity
Excessive endoplasmic reticulum stress and decreased neuroplasticity-associated proteins in prefrontal cortex of obese rats and the regulatory effects of aerobic exercise.
Obesity
Genetic Targeting of GRP78 in the VMH Improves Obesity Independently of Food Intake.
Obesity
Genetic variation in the stress protein hsp70-2 gene is highly associated with obesity.
Obesity
Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes.
Obesity
Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance.
Obesity
GRP78 levels, regional fat distribution and endometrial cáncer.
Obesity
Heat shock protein 60 and adipocytes: characterization of a ligand-receptor interaction.
Obesity
Heat Shock Protein 90 Alpha, Lass B Member 1: a Key Regulative Gene of Monitoring Duodenal Tumor for Obesity Induced by High-Fat Diet.
Obesity
Heat shock proteins in obesity: links to cardiovascular disease.
Obesity
High-fat diet-induced obesity amplifies HSP70-2a and HSP90 expression in testicular tissue; correlation with proliferating cell nuclear antigen (PCNA).
Obesity
HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue.
Obesity
HSP72 is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle.
Obesity
Hsp90 blockers inhibit adipocyte differentiation and fat mass accumulation.
Obesity
Hsp90 chaperones PPAR? and regulates differentiation and survival of 3T3-L1 adipocytes.
Obesity
Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells.
Obesity
Loss and gain of function of Grp75 or mitofusin 2 distinctly alter cholesterol metabolism, but all promote triglyceride accumulation in hepatocytes.
Obesity
MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort.
Obesity
Modification of lung endoplasmic reticulum genes expression and NF-kB protein levels in obese ovalbumin-sensitized male and female rats.
Obesity
Obesity: Hsp60 integrates central crosstalk.
Obesity
Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone.
Obesity
Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese.
Obesity
Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity.
Obesity
Proteomic Analysis for Antiobesity Potential of Capsaicin on White Adipose Tissue in Rats Fed with a High Fat Diet.
Obesity
Proteomic analysis of primary cultures of human adipose-derived stem cells: modulation by Adipogenesis.
Obesity
Radicicol, a heat shock protein 90 inhibitor, inhibits differentiation and adipogenesis in 3T3-L1 preadipocytes.
Obesity
Reduction of Hypothalamic ER Stress Activates Browning of White Fat and Ameliorates Obesity.
Obesity
Relationship Between Heat Shock Protein Expression and Obesity With and Without Metabolic Syndrome.
Obesity
The Drosophila ETV5 Homologue Ets96B: Molecular Link between Obesity and Bipolar Disorder.
Obesity
Tissue cell stress response to obesity and its interaction with late gestation diet.
Obesity, Morbid
Heat Shock Protein 60 in Obesity: Effect of Bariatric Surgery and its Relation to Inflammation and Cardiovascular Risk.
Obstetric Labor, Premature
Endoplasmic reticulum stress is increased after spontaneous labor in human fetal membranes and myometrium where it regulates the expression of prolabor mediators.
Ocular Hypertension
Heat shock proteins in the retina: focus on HSP70 and alpha crystallins in ganglion cell survival.
Oligodendroglioma
GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis.
Oligodendroglioma
Heat shock protein expression in human gliomas.
Oligospermia
Heat shock protein and heat shock factor expression in sperm: relation to oligozoospermia and varicocele.
Onchocerciasis
Fine specificity of autoantibodies to calreticulin: epitope mapping and characterization.
Oncogene Addiction
D-Propranolol Impairs EGFR Trafficking and Destabilizes Mutant p53 Counteracting AKT Signaling and Tumor Malignancy.
Oncogene Addiction
Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress.
Oncogene Addiction
Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions.
Oncogene Addiction
Optical Imaging of Treatment-Related Tumor Cell Death Using a Heat Shock Protein-90 Alkylator.
Oncogene Addiction
SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
Oncogene Addiction
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation.
Optic Atrophy
Mitochondrial serine protease Omi/HtrA2 accentuates brain ischemia/reperfusion injury in rats and oxidative stress injury in vitro by modulating mitochondrial stress proteins CHOP and ClpP and physically interacting with mitochondrial fusion protein OPA1.
Optic Atrophy, Autosomal Dominant
Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy.
Optic Nerve Diseases
Anti-Ro/SS-A positivity and heat shock protein antibodies in patients with normal-pressure glaucoma.
Optic Nerve Injuries
Heat shock protein 72 confers protection in retinal ganglion cells and lateral geniculate nucleus neurons via blockade of the SAPK/JNK pathway in a chronic ocular-hypertensive rat model.
Optic Nerve Injuries
Induction and phosphorylation of the small heat shock proteins HspB1/Hsp25 and HspB5/?B-crystallin in the rat retina upon optic nerve injury.
Oral Submucous Fibrosis
Expression of heat shock protein70 in oral submucous fibrosis and oral squamous cell carcinoma: an immunohistochemical study.
Oral Submucous Fibrosis
In-silico analysis of heat shock protein 47 for identifying the novel therapeutic agents in the management of oral submucous fibrosis.
Oral Ulcer
Association between the 65-kilodalton heat shock protein, Streptococcus sanguis, and the corresponding antibodies in Behçet's syndrome.
Oral Ulcer
Recognition of a unique peptide epitope of the mycobacterial and human heat shock protein 65-60 antigen by T cells of patients with recurrent oral ulcers.
Osteitis Deformans
Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.
Osteoarthritis
A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis.
Osteoarthritis
Advanced osteoarthritis in humans is associated with altered collagen VI expression and upregulation of ER-stress markers Grp78 and bag-1.
Osteoarthritis
Analysis of 70Kd heat shock protein expression in patients with internal derangement of the temporomandibular joint.
Osteoarthritis
Combined microwave irradiation and intraarticular glutamine administration-induced HSP70 expression therapy prevents cartilage degradation in a rat osteoarthritis model.
Osteoarthritis
Effects of laser irradiation on arthritic histopathology and heat shock protein 70 expression in C57 black mice with osteoarthritis.
Osteoarthritis
Heat shock protein gene expression profile may differentiate between rheumatoid arthritis, osteoarthritis, and healthy controls.
Osteoarthritis
Hsp90 inhibition protects against biomechanically induced osteoarthritis in rats.
Osteoarthritis
Hsp90 mediates insulin-like growth factor 1 and interleukin-1beta signaling in an age-dependent manner in equine articular chondrocytes.
Osteoarthritis
Hyaluronate on heat shock protein and synovial cells in a canine model of osteoarthritis.
Osteoarthritis
Local induction of heat shock protein 70 (Hsp70) by proteasome inhibition confers chondroprotection during surgically induced osteoarthritis in the rat knee.
Osteoarthritis
MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Osteoarthritis
RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family.
Osteoarthritis
Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis.
Osteoarthritis, Hip
[Heat shock protein antibodies and other chlamydial antigens in various diseases and their occurrence in blood donors]
Osteoarthritis, Knee
Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis.
Osteoarthritis, Knee
Circulating and Synovial Fluid Heat Shock Protein 70 Are Correlated with Severity in Knee Osteoarthritis.
Osteochondritis Dissecans
Autophagy in farm animals: current knowledge and future challenges.
Osteochondrodysplasias
Clinical efficiency and safety of Hsp90 inhibitor Novobiocin in avian tibial dyschondroplasia.
Osteochondrodysplasias
Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia.
Osteochondrodysplasias
In Vitro Effect of Apigenin and Danshen in Tibial Dyschondroplasia Through Inhibition of Heat-Shock Protein 90 and Vascular Endothelial Growth Factor Expressions in Avian Growth Plate Cells.
Osteochondrodysplasias
Recovery of Chicken Growth Plate by Heat-Shock Protein 90 Inhibitors Epigallocatechin-3-Gallate and Apigenin in Thiram-Induced Tibial Dyschondroplasia.
Osteogenesis Imperfecta
Endoplasmic reticulum-mediated quality control of type I collagen production by cells from osteogenesis imperfecta patients with mutations in the pro alpha 1 (I) chain carboxyl-terminal propeptide which impair subunit assembly.
Osteogenesis Imperfecta
Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen.
Osteolysis
The Escherichia coli chaperonin 60 (groEL) is a potent stimulator of osteoclast formation.
Osteolysis
The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line.
Osteolysis
[Effect of oxidative stress on periprosthetic osteolysis induced by TCP wear particles in mouse calvaria and its mechanism].
Osteolysis
[Validity of the Morawietz classification for evaluation of periprosthetic tissue].
Osteophyte
Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis.
Osteoporosis
Autoreactivity to glucose regulated protein 78 links emphysema and osteoporosis in smokers.
Osteoporosis
Heat shock protein 90 is required for increased DNA binding activity of activator protein-1, a heterodimer of Fos/JunD, in rheumatoid synovial cells under inflammatory stimuli.
Osteoporosis
Hsp60 and human aging: Les liaisons dangereuses.
Osteoporosis
Inhibitors of heat shock protein 90 augment endothelin?1?induced heat shock protein 27 through the SAPK/JNK signaling pathway in osteoblasts.
Osteoporosis
Osteoblastic cell secretome: a novel role for progranulin during risedronate treatment.
Osteoporosis
Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis.
Osteoporosis
Serum levels of phosphorylated heat shock protein 27 (pHSP27) are associated with bone mineral density in pre- & postmenopausal women: A pilot study.
Osteoporosis
Specific induction of heat shock protein 27 by glucocorticoid in osteoblasts.
Osteosarcoma
17-AAG and Apoptosis, Autophagy, and Mitophagy in Canine Osteosarcoma Cell Lines.
Osteosarcoma
A correlation analysis between tumor imaging changes and p-AKT and HSP70 expression in tumor cells after osteosarcoma chemotherapy.
Osteosarcoma
A new antisarcoma strategy: multisubtype heat shock protein/peptide immunotherapy combined with PD-L1 immunological checkpoint inhibitors.
Osteosarcoma
AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma.
Osteosarcoma
Analysis of HSP27 and the autophagy marker LC3B+ puncta following preoperative chemotherapy identifies high-risk osteosarcoma patients.
Osteosarcoma
Anesthesia for euthanasia influences mRNA expression in healthy mice and after traumatic brain injury.
Osteosarcoma
Antibodies to heat shock protein 90 in osteosarcoma patients correlate with response to neoadjuvant chemotherapy.
Osteosarcoma
Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor.
Osteosarcoma
ATF4 destabilizes RET through nonclassical GRP78 inhibition to enhance chemosensitivity to bortezomib in human osteosarcoma.
Osteosarcoma
Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression.
Osteosarcoma
Coffee intake mitigated inflammation and obesity-induced insulin resistance in skeletal muscle of high-fat diet-induced obese mice.
Osteosarcoma
Combining GRP78 suppression and MK2206-induced Akt inhibition decreases doxorubicin-induced P-glycoprotein expression and mitigates chemoresistance in human osteosarcoma.
Osteosarcoma
Critical role of heat shock protein 27 in bufalin-induced apoptosis in human osteosarcomas: a proteomic-based research.
Osteosarcoma
Design and synthesis of pyrimidinyl acyl thioureas as novel Hsp90 inhibitors in invasive ductal breast cancer and its bone metastasis.
Osteosarcoma
Distinct profiles of oxidative stress-related and matrix proteins in adult bone and soft tissue osteosarcoma and desmoid tumors: A proteomics study.
Osteosarcoma
Effects of Ezrin and Heat Shock Protein 70 on Apoptosis and Proliferation of Human Osteosarcoma Cells.
Osteosarcoma
Effects of hyperthermia on heat shock protein expression, alkaline phosphatase activity and proliferation in human osteosarcoma cells.
Osteosarcoma
Experimental study of inhibitory effects of diallyl trisulfide on the growth of human osteosarcoma Saos-2 cells by downregulating expression of glucose-regulated protein 78.
Osteosarcoma
Exposure of Wistar rats to 24-h psycho-social stress alters gene expression in the inferior colliculus.
Osteosarcoma
Expression and its clinical significance of heat shock protein gp96 in human osteosarcoma.
Osteosarcoma
Expression and significance of glucose-regulated protein 78 in human osteosarcoma.
Osteosarcoma
Expression of heat shock proteins in osteosarcomas.
Osteosarcoma
Extracellular heat shock protein HSP90beta secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-beta1.
Osteosarcoma
Genetic response to low?intensity ultrasound on mouse ST2 bone marrow stromal cells.
Osteosarcoma
GRP78 inhibition enhances ATF4-induced cell death by the deubiquitination and stabilization of CHOP in human osteosarcoma.
Osteosarcoma
Heat shock protein 72 expression in osteosarcomas correlates with good response to neoadjuvant chemotherapy.
Osteosarcoma
Heat shock protein 90B1 plays an oncogenic role and is a target of microRNA-223 in human osteosarcoma.
Osteosarcoma
Heat shock protein expression analysis in canine osteosarcoma reveals HSP60 as a potentially relevant therapeutic target.
Osteosarcoma
Heat shock protein expression in canine osteosarcoma.
Osteosarcoma
Hsp90 inhibitor 17?AAG inhibits stem cell?like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway.
Osteosarcoma
Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells.
Osteosarcoma
Hsp90 inhibitors deplete key anti-apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin.
Osteosarcoma
HSP90 regulates osteosarcoma cell apoptosis by targeting the p53/TCF-1-mediated transcriptional network.
Osteosarcoma
Hyperthermia reduces migration of osteosarcoma by suppression of autocrine motility factor.
Osteosarcoma
Influence of ezrin-shRNA in combination with HSP70 on the apoptosis and proliferation of osteosarcoma cells.
Osteosarcoma
Investigation of anticancer activities of STA-9090 (ganetespib) as a second generation HSP90 inhibitor in Saos-2 osteosarcoma cells.
Osteosarcoma
Kuanoniamine C stimulates bortezomib-induced cell death via suppression of glucose-regulated protein 78 in osteosarcoma.
Osteosarcoma
microRNA-338-3p inhibits proliferation, migration, invasion, and EMT in osteosarcoma cells by targeting activator of 90 kDa heat shock protein ATPase homolog 1.
Osteosarcoma
Mild microwave ablation combined with HSP90 and TGF??1 inhibitors enhances the therapeutic effect on osteosarcoma.
Osteosarcoma
miR-485-5p/HSP90 axis blocks Akt1 phosphorylation to suppress osteosarcoma cell proliferation and migration via PI3K/AKT pathway.
Osteosarcoma
Novel findings in gene expression detected in human osteosarcoma by cDNA microarray.
Osteosarcoma
OS-9 facilitates turnover of nonnative GRP94 marked by hyperglycosylation.
Osteosarcoma
Overexpression of resistance-related proteins (metallothioneins, glutathione-S-transferase pi, heat shock protein 27, and lung resistance-related protein) in osteosarcoma. Relationship with poor prognosis.
Osteosarcoma
Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy.
Osteosarcoma
Photodynamic therapy reduces the inhibitory effect of osteosarcoma cells on dendritic cells by upregulating HSP70.
Osteosarcoma
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Osteosarcoma
Polydatin enhances the chemosensitivity of osteosarcoma cells to paclitaxel.
Osteosarcoma
Protein profiling of osteosarcoma tissue and soft callus unveils activation of the unfolded protein response pathway.
Osteosarcoma
Rab22a-NeoF1 fusion protein promotes osteosarcoma lung metastasis through its secretion into exosomes.
Osteosarcoma
Serum antibodies against the heat shock protein 60 are elevated in patients with osteosarcoma.
Osteosarcoma
Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors.
Osteosarcoma
Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy.
Osteosarcoma
Suppression of heat shock protein 70 by siRNA enhances the antitumor effects of cisplatin in cultured human osteosarcoma cells.
Osteosarcoma
Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures.
Osteosarcoma
Syntenic conservation of HSP70 genes in cattle and humans.
Osteosarcoma
Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways.
Osteosarcoma
Targeting GRP78 enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide-? methyl ester-mediated photodynamic therapy via the Wnt/?-catenin signaling pathway.
Osteosarcoma
Targeting HSP70 and GRP78 in canine osteosarcoma cells in combination with doxorubicin chemotherapy.
Osteosarcoma
The effects of MEX3A knockdown on proliferation, apoptosis and migration of osteosarcoma cells.
Osteosarcoma
The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma.
Osteosarcoma
The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model.
Osteosarcoma
The novel HSP90 inhibitor STA-1474 exhibits biologic activity against osteosarcoma cell lines.
Osteosarcoma
Transcriptional regulation of Runx2 by HSP90 controls osteosarcoma apoptosis via the AKT/GSK-3?/?-catenin signaling.
Osteosarcoma
Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis.
Osteosarcoma
Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.
Osteosarcoma
Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha.
Otitis Media
Expression of HSP70 and Its Relation with Other Cytokines in Human Middle Ear Effusion.
Otitis Media with Effusion
Expression of HSP70 and Its Relation with Other Cytokines in Human Middle Ear Effusion.
Ototoxicity
Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32.
Ototoxicity
Expression of heat shock protein 72 in rat cochlea with cisplatin-induced acute ototoxicity.
Ototoxicity
Geldanamycin induces production of heat shock protein 70 and partially attenuates ototoxicity caused by gentamicin in the organ of Corti explants.
Ototoxicity
Heat shock protein 70 and cellular disturbances in cochlear cisplatin ototoxicity model.
Ototoxicity
Heat shock protein 70 delays gentamicin-induced vestibular hair cell death.
Ototoxicity
Role of Hsp90/Akt pathway in the pathogenesis of gentamicin-induced hearing loss.
Ototoxicity
[Expression of heat shock protein 70 mRNA in guinea pig cochlea with ototoxicity of gentamicin]
Ototoxicity
[Heat shock response in guinea pigs cochlea with gentamicin ototoxicity].
Ovarian Cysts
Expression of the 60 kDa heat shock protein in peritoneal fluids from women with endometriosis: implications for endometriosis-associated infertility.
Ovarian Cysts
Heat Shock Protein 70 and Sex Steroid Receptors in the Follicular Structures of Induced Ovarian Cysts.
Ovarian Cysts
Unfolded protein response, a link between endometrioid ovarian carcinoma and endometriosis: A pilot study.
Ovarian Diseases
Heat Shock Protein 70 and Sex Steroid Receptors in the Follicular Structures of Induced Ovarian Cysts.
Ovarian Diseases
Heat shock protein patterns in the bovine ovary and relation with cystic ovarian disease.
Ovarian Neoplasms
18?-Glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.
Ovarian Neoplasms
A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma.
Ovarian Neoplasms
A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition.
Ovarian Neoplasms
An aptamer interacting with heat shock protein 70 shows therapeutic effects and prognostic ability in serous ovarian cancer.
Ovarian Neoplasms
An HSP90-mimic peptide revealed by fingerprinting the pool of antibodies from ovarian cancer patients.
Ovarian Neoplasms
An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
Ovarian Neoplasms
Anti-KDEL-coated nanoparticles: A promising tumor targeting approach for ovarian cancer?
Ovarian Neoplasms
Antibodies against Hsp60 and Hsp65 in the sera of women with ovarian cancer.
Ovarian Neoplasms
Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma.
Ovarian Neoplasms
BAG-4/SODD and associated antiapoptotic proteins are linked to aggressiveness of epithelial ovarian cancer.
Ovarian Neoplasms
CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signaling in ovarian cancer cells.
Ovarian Neoplasms
Cancer immunotherapy using irradiated tumor cells secreting heat shock protein 70.
Ovarian Neoplasms
Change in the localization of heat shock protein 27 (HSP 27) in BG-1 human ovarian cancer cells following treatment by the ether lipid ET-18-OCH3.
Ovarian Neoplasms
Circulating GRP78 antibodies from ovarian cancer patients: a promising tool for cancer cell targeting drug delivery system?
Ovarian Neoplasms
Cisplatin-induced senescence in ovarian cancer cells is mediated by GRP78.
Ovarian Neoplasms
Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
Ovarian Neoplasms
Correction: Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.
Ovarian Neoplasms
Design and encapsulation of anticancer dual HSP27 and HER2 inhibitor into low density lipoprotein to target ovarian cancer cells.
Ovarian Neoplasms
Developing a genetic signature to predict drug response in ovarian cancer.
Ovarian Neoplasms
Drug-induced Modulation of Heat Shock Protein HSPB1 in an Ovarian Cancer Cell Model.
Ovarian Neoplasms
ErbB2 overexpression in an ovarian cancer cell line confers sensitivity to the HSP90 inhibitor geldanamycin.
Ovarian Neoplasms
Erratum: Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer.
Ovarian Neoplasms
Expression and clinical role of antiapoptotic proteins of the bag, heat shock, and Bcl-2 families in effusions, primary tumors, and solid metastases in ovarian carcinoma.
Ovarian Neoplasms
Expression and localization of GRP75 in human epithelial tumors and normal tissues.
Ovarian Neoplasms
Expression of heat shock protein 20 inversely correlated with tumor progression in patients with ovarian cancer.
Ovarian Neoplasms
Expression of the heat shock protein HSP27 in human ovarian cancer.
Ovarian Neoplasms
Geldanamycin, an inhibitor of Hsp90, increases paclitaxel-mediated toxicity in ovarian cancer cells through sustained activation of the p38/H2AX axis.
Ovarian Neoplasms
Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
Ovarian Neoplasms
GRP75 modulates oncogenic Dbl-driven endocytosis derailed via the CHIP-mediated ubiquitin degradation pathway.
Ovarian Neoplasms
GRP78 knockdown does not affect cytotoxicity of cisplatin in ovarian cancer cells.
Ovarian Neoplasms
GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach.
Ovarian Neoplasms
Heat shock protein 27 (hsp27) in patients with ovarian cancer.
Ovarian Neoplasms
Heat Shock Protein 60 (HSP60) Serves as a Potential Target for the Sensitization of Chemoresistant Ovarian Cancer Cells.
Ovarian Neoplasms
Heat shock protein 70-2 (HSP70-2) a novel cancer testis antigen that promotes growth of ovarian cancer.
Ovarian Neoplasms
Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3?/?-Catenin Signaling.
Ovarian Neoplasms
Heat Shock Protein HSP27 Secretion by Ovarian Cancer Cells Is Linked to Intracellular Expression Levels, Occurs Independently of the Endoplasmic Reticulum Pathway and HSP27's Phosphorylation Status, and Is Mediated by Exosome Liberation.
Ovarian Neoplasms
Heat shock proteins, cell survival and drug resistance: the mitochondrial chaperone TRAP1, a potential novel target for ovarian cancer therapy.
Ovarian Neoplasms
High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer.
Ovarian Neoplasms
HSP27 is required for invasion and metastasis triggered by hepatocyte growth factor.
Ovarian Neoplasms
HSP60 Predicts Survival in Advanced Serous Ovarian Cancer.
Ovarian Neoplasms
HSP70 inhibition synergistically enhances the effects of magnetic fluid hyperthermia in ovarian cancer.
Ovarian Neoplasms
HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer.
Ovarian Neoplasms
Hsp90 inhibitor geldanamycin enhances the antitumor efficacy of enediyne lidamycin in association with reduced DNA damage repair.
Ovarian Neoplasms
Hsp90 inhibitor SY-016 induces G2/M arrest and apoptosis in paclitaxel-resistant human ovarian cancer cells.
Ovarian Neoplasms
Hsp90 Is a Novel Target Molecule of CDDO-Me in Inhibiting Proliferation of Ovarian Cancer Cells.
Ovarian Neoplasms
Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library.
Ovarian Neoplasms
IgA antibodies to the 27-kDa heat-shock protein in the genital tracts of women with gynecologic cancers.
Ovarian Neoplasms
Immunohistochemical detection of HSP60-expression in human ovarian cancer. Correlation with survival in a series of 247 patients.
Ovarian Neoplasms
Increased expression of heat shock protein 70 in adherent ovarian cancer and mesothelioma following treatment with manumycin, a farnesyl transferase inhibitor.
Ovarian Neoplasms
Increased temperature-related adeno-associated virus vectors transduction of ovarian cancer cells - essential signatures of AAV receptor and heat shock proteins.
Ovarian Neoplasms
Inhibition of mortalin expression reverses cisplatin resistance and attenuates growth of ovarian cancer cells.
Ovarian Neoplasms
Insight into residues involved in the structure and function of the breast cancer associated protein human gamma synuclein.
Ovarian Neoplasms
Involvement of GRP78 in the Resistance of Ovarian Carcinoma Cells to Paclitaxel.
Ovarian Neoplasms
Lamin-A interacting protein Hsp90 is required for DNA damage repair and chemoresistance of ovarian cancer cells.
Ovarian Neoplasms
Metabolic markers and HSP60 in chemonaive serous solid ovarian cancer versus ascites.
Ovarian Neoplasms
Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors.
Ovarian Neoplasms
MiR-181c sensitizes ovarian cancer cells to paclitaxel by targeting GRP78 through the PI3K/Akt pathway.
Ovarian Neoplasms
New agents for the treatment of ovarian cancer: the next generation.
Ovarian Neoplasms
NF-?B p65 promotes ovarian cancer cell proliferation and migration via regulating mortalin.
Ovarian Neoplasms
Novel ovarian cancer maintenance therapy targeted at mortalin and mutant p53.
Ovarian Neoplasms
Oncogenic role of mortalin contributes to ovarian tumorigenesis by activating the MAPK-ERK pathway.
Ovarian Neoplasms
Osmotic and heat stress-dependent regulation of MLK4? and MLK3 by the CHIP E3 ligase in ovarian cancer cells.
Ovarian Neoplasms
Part I of GANNET53: A European Multicenter Phase I/II Trial of the Hsp90 Inhibitor Ganetespib Combined With Weekly Paclitaxel in Women With High-Grade, Platinum-Resistant Epithelial Ovarian Cancer-A Study of the GANNET53 Consortium.
Ovarian Neoplasms
Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer.
Ovarian Neoplasms
Pharmacokinetic-pharmacodynamic relationships for the heat shock protein 90 molecular chaperone inhibitor 17-allylamino, 17-demethoxygeldanamycin in human ovarian cancer xenograft models.
Ovarian Neoplasms
Priming with HDAC Inhibitors Sensitizes Ovarian Cancer Cells to Treatment with Cisplatin and HSP90 Inhibitors.
Ovarian Neoplasms
Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models.
Ovarian Neoplasms
Progression of the role of CRYAB in signaling pathways and cancers.
Ovarian Neoplasms
Purified autoantibodies against glucose-regulated protein 78 (GRP78) promote apoptosis and decrease invasiveness of ovarian cancer cells.
Ovarian Neoplasms
Regulation by heat shock protein 22 (HSPB8) of transforming growth factor-?-induced ovary cancer cell migration.
Ovarian Neoplasms
Relationship between heat shock protein 60 (HSP60) mRNA expression and resistance to platinum analogues in human ovarian and bladder carcinoma cell lines.
Ovarian Neoplasms
Reversing drug resistance of cisplatin by hsp90 inhibitors in human ovarian cancer cells.
Ovarian Neoplasms
Role of PAR-4 in ovarian cancer.
Ovarian Neoplasms
Secretion of cytokines and heat shock protein (HspA1A) by ovarian cancer cells depending on the tumor type and stage of disease.
Ovarian Neoplasms
Serologic evidence of past infection with Chlamydia trachomatis, in relation to ovarian cancer.
Ovarian Neoplasms
Small interfering RNA-mediated silencing of heat shock protein 27 (HSP27) Increases chemosensitivity to paclitaxel by increasing production of reactive oxygen species in human ovarian cancer cells (HO8910).
Ovarian Neoplasms
Stress-Adaptive Response in Ovarian Cancer Drug Resistance: Role of TRAP1 in Oxidative Metabolism-Driven Inflammation.
Ovarian Neoplasms
Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.
Ovarian Neoplasms
Syngeneic Murine Ovarian Cancer Model Reveals That Ascites Enriches for Ovarian Cancer Stem-Like Cells Expressing Membrane GRP78.
Ovarian Neoplasms
Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation.
Ovarian Neoplasms
Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cells.
Ovarian Neoplasms
The expression of FAS-associated factor 1 and heat shock protein 70 in ovarian cancer.
Ovarian Neoplasms
The involvement of small heat shock protein in chemoresistance in ovarian cancer - in vitro study.
Ovarian Neoplasms
Unfolded protein response, a link between endometrioid ovarian carcinoma and endometriosis: A pilot study.
Ovarian Neoplasms
[Effect of glucose regulated protein 78 on autophagy and apoptosis in ovarian epithelial carcinoma].
Ovarian Neoplasms
[Effects of ascites derived exosomes on the stemness and invasion ability of ovarian cancer stem-like cell].
Ovarian Neoplasms
[Inhibition of GRP78 expression reverses cisplatin resistance in human ovarian cancer].
Ovarian Torsion
Can adnexal torsion be predicted by measuring plasma heat shock protein 70 level? An experimental study.
Overweight
Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study.
Overweight
Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice-a new potential probiotic for appetite and body weight management.
Paget Disease, Extramammary
Heat shock protein 105 is overexpressed in squamous cell carcinoma and extramammary Paget disease but not in basal cell carcinoma.
Pancreatic Neoplasms
(-)-Epigallocatechin-3-gallate Inhibits Hsp90 Function by Impairing Hsp90 Association with Co-chaperones in Pancreatic Cancer Cell Line Mia Paca-2.
Pancreatic Neoplasms
A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells.
Pancreatic Neoplasms
A Phase II Study of Ganetespib as Second-line or Third-line Therapy for Metastatic Pancreatic Cancer.
Pancreatic Neoplasms
A phase II study of the HSP90 inhibitor AUY922 in chemotherapy refractory advanced pancreatic cancer.
Pancreatic Neoplasms
A Randomized, Double-Blinded, Phase II Trial of Gemcitabine and Nab-Paclitaxel Plus Apatorsen or Placebo in Patients with Metastatic Pancreatic Cancer: The RAINIER Trial.
Pancreatic Neoplasms
Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers.
Pancreatic Neoplasms
Antiproliferative effect of HSP90 inhibitor Y306zh against pancreatic cancer is mediated by interruption of AKT and MAPK signaling pathways.
Pancreatic Neoplasms
Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer.
Pancreatic Neoplasms
Antitumor activity of mHSP65-TTL enhanced by administration of low dose cyclophosphamide in pancreatic cancer-bearing mice.
Pancreatic Neoplasms
Changes in the Expression of Glucose-regulated Protein 78 in the Occurrence and Progression of Pancreatic Cancer in Mouse Models.
Pancreatic Neoplasms
Chaperone-mediated autophagy degradation of IGF-1R? induced by NVP-AUY922 in pancreatic cancer.
Pancreatic Neoplasms
CHIP is a novel tumor suppressor in pancreatic cancer through targeting EGFR.
Pancreatic Neoplasms
Concomitant inhibition of HSP90, its mitochondrial localized homologue TRAP1 and HSP27 by green tea in pancreatic cancer HPAF-II cells.
Pancreatic Neoplasms
Design and Function of Engineered Protein Nanocages as a Drug Delivery System for Targeting Pancreatic Cancer Cells via Neuropilin-1.
Pancreatic Neoplasms
Dual mode of cancer cell destruction for pancreatic cancer therapy using Hsp90 inhibitor loaded polymeric nano magnetic formulation.
Pancreatic Neoplasms
Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer.
Pancreatic Neoplasms
Enzyme-treated Asparagus Extract Down-regulates Heat Shock Protein 27 of Pancreatic Cancer Cells.
Pancreatic Neoplasms
Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Pancreatic Neoplasms
ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining "stemness".
Pancreatic Neoplasms
Expression of heat shock protein 70 modulates the chemoresponsiveness of pancreatic cancer.
Pancreatic Neoplasms
Expression of novel tumor markers of pancreatic adenocarcinomas in intrahepatic cholangiocarcinomas.
Pancreatic Neoplasms
GRP78 promotes the invasion of pancreatic cancer cells by FAK and JNK.
Pancreatic Neoplasms
GRP78-mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells.
Pancreatic Neoplasms
Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma.
Pancreatic Neoplasms
Heat Shock Protein 27 Expression in EUS-FNA Samples Can Predict Gemcitabine Sensitivity in Pancreatic Cancer.
Pancreatic Neoplasms
Heat shock protein 47 confers chemoresistance on pancreatic cancer cells by interacting with calreticulin and IRE1?.
Pancreatic Neoplasms
Heat Shock Protein 90 Inhibitor Effects on Pancreatic Cancer Cell Cultures.
Pancreatic Neoplasms
Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer.
Pancreatic Neoplasms
HIF-1alpha and STAT3 client proteins interacting with the cancer chaperone Hsp90: Therapeutic Considerations.
Pancreatic Neoplasms
HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells.
Pancreatic Neoplasms
HSP90 is a promising target in gemcitabine and 5-fluorouracil resistant pancreatic cancer.
Pancreatic Neoplasms
Hyperthermia potentiates oncolytic herpes viral killing of pancreatic cancer through a heat shock protein pathway.
Pancreatic Neoplasms
Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells.
Pancreatic Neoplasms
Inhibition of HSP90 overcomes resistance to chemotherapy and radiotherapy in pancreatic cancer.
Pancreatic Neoplasms
Interaction between HSP60 and {beta}-catenin promotes metastasis.
Pancreatic Neoplasms
Interferon-gamma down-regulates heat shock protein 27 of pancreatic cancer cells and helps in the cytotoxic effect of gemcitabine.
Pancreatic Neoplasms
KNK437 downregulates heat shock protein 27 of pancreatic cancer cells and enhances the cytotoxic effect of gemcitabine.
Pancreatic Neoplasms
Knockdown of glucose-regulated protein 78 enhances poly(ADP-ribose) polymerase cleavage in human pancreatic cancer cells exposed to endoplasmic reticulum stress.
Pancreatic Neoplasms
Maslinic acid induces autophagy by down-regulating HSPA8 in pancreatic cancer cells.
Pancreatic Neoplasms
MEK Inhibition Potentiates the Activity of Hsp90 Inhibitor 17-AAG against Pancreatic Cancer Cells.
Pancreatic Neoplasms
Molecular chaperone HspB2 inhibited pancreatic cancer cell proliferation via activating p53 downstream gene RPRM, BAI1, and TSAP6.
Pancreatic Neoplasms
Mortalin expression in pancreatic cancer and its clinical and prognostic significance.
Pancreatic Neoplasms
Mutant p53, Stabilized by Its Interplay with HSP90, Activates a Positive Feed-Back Loop Between NRF2 and p62 that Induces Chemo-Resistance to Apigenin in Pancreatic Cancer Cells.
Pancreatic Neoplasms
Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model.
Pancreatic Neoplasms
Novel agents in the treatment of pancreatic adenocarcinoma.
Pancreatic Neoplasms
Novel triazole ribonucleoside down-regulates heat shock protein 27 and induces potent anticancer activity on drug-resistant pancreatic cancer.
Pancreatic Neoplasms
Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth.
Pancreatic Neoplasms
Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors.
Pancreatic Neoplasms
Overexpression of heat shock protein (hsp) 70 associated with abnormal p53 expression in cancer of the pancreas.
Pancreatic Neoplasms
Overexpression of heat shock protein 27 (HSP27) increases gemcitabine sensitivity in pancreatic cancer cells through S-phase arrest and apoptosis.
Pancreatic Neoplasms
Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo.
Pancreatic Neoplasms
PET imaging of Hsp90 expression in pancreatic cancer using a new 64Cu-labeled dimeric Sansalvamide A decapeptide.
Pancreatic Neoplasms
Phase II trial of gemcitabine and tanespimycin (17AAG) in metastatic pancreatic cancer: a Mayo Clinic Phase II Consortium study.
Pancreatic Neoplasms
Phosphorylation status of heat shock protein 27 plays a key role in gemcitabine-induced apoptosis of pancreatic cancer cells.
Pancreatic Neoplasms
Potentiation of chemotherapeutics by the Hsp90 antagonist geldanamycin requires a steady serum condition.
Pancreatic Neoplasms
Proteomics finding heat shock protein 27 as a biomarker for resistance of pancreatic cancer cells to gemcitabine.
Pancreatic Neoplasms
Radiofrequency ablation, heat shock protein 70 and potential anti-tumor immunity in hepatic and pancreatic cancers: a minireview.
Pancreatic Neoplasms
RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation.
Pancreatic Neoplasms
Role for NAD(P)H:quinone oxidoreductase 1 and manganese-dependent superoxide dismutase in 17-(Allylamino)-17-demethoxygeldanamycin-induced heat shock protein 90 inhibition in pancreatic cancer cells.
Pancreatic Neoplasms
Role of GRP78 inhibiting artesunate-induced ferroptosis in KRAS mutant pancreatic cancer cells.
Pancreatic Neoplasms
Role of heat shock protein 27 in gemcitabine-resistant human pancreatic cancer: Comparative proteomic analyses.
Pancreatic Neoplasms
RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients.
Pancreatic Neoplasms
Selective Cytotoxicity of Ponciri Fructus against Glucose-Deprived PANC-1 Human Pancreatic Cancer Cells via Blocking Activation of GRP78.
Pancreatic Neoplasms
Serum HSP70: A Novel Biomarker for Early Detection of Pancreatic Cancer.
Pancreatic Neoplasms
Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159.
Pancreatic Neoplasms
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway.
Pancreatic Neoplasms
Steady-State Levels of Phosphorylated Mitogen-Activated Protein Kinase Kinase 1/2 Determined by Mortalin/HSPA9 and Protein Phosphatase 1 Alpha in KRAS and BRAF Tumor Cells.
Pancreatic Neoplasms
Structure-activity relationship (SAR) of withanolides to inhibit Hsp90 for its activity in pancreatic cancer cells.
Pancreatic Neoplasms
Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.
Pancreatic Neoplasms
Sulforaphane Potentiates the Efficacy of 17-Allylamino 17-Demethoxygeldanamycin Against Pancreatic Cancer Through Enhanced Abrogation of Hsp90 Chaperone Function.
Pancreatic Neoplasms
Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures.
Pancreatic Neoplasms
Synergistic Antipancreatic Tumor Effect by Simultaneously Targeting Hypoxic Cancer Cells With HSP90 Inhibitor and Glycolysis Inhibitor.
Pancreatic Neoplasms
Synthetic small interfering RNA targeting heat shock protein 105 induces apoptosis of various cancer cells both in vitro and in vivo.
Pancreatic Neoplasms
Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is highly active against pancreatic cancer models.
Pancreatic Neoplasms
Targeting cell surface GRP78 enhances pancreatic cancer radiosensitivity through YAP/TAZ protein signaling.
Pancreatic Neoplasms
Targeting Heat Shock Protein 90 in Pancreatic Cancer Impairs Insulin-like Growth Factor-I Receptor Signaling, Disrupts an Interleukin-6/Signal-Transducer and Activator of Transcription 3/Hypoxia-Inducible Factor-1{alpha} Autocrine Loop, and Reduces Orthotopic Tumor Growth.
Pancreatic Neoplasms
Targeting HSP90 by the novel inhibitor NVP-AUY922 reduces growth and angiogenesis of pancreatic cancer.
Pancreatic Neoplasms
Targeting the Janus-activated kinase-2-STAT3 signalling pathway in pancreatic cancer using the HSP90 inhibitor ganetespib.
Pancreatic Neoplasms
The Clinical Significance of Phosphorylated Heat Shock Protein 27 (HSPB1) in Pancreatic Cancer.
Pancreatic Neoplasms
The Effects of HSP27 on Gemcitabine-Resistant Pancreatic Cancer Cell Line Through Snail.
Pancreatic Neoplasms
The hydroxyquinoline analog YUM70 inhibits GRP78 to induce ER stress-mediated apoptosis in pancreatic cancer.
Pancreatic Neoplasms
The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer.
Pancreatic Neoplasms
Triptolide cooperates with Cisplatin to induce apoptosis in gemcitabine-resistant pancreatic cancer.
Pancreatic Neoplasms
Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.
Pancreatic Neoplasms
Triptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation.
Pancreatic Neoplasms
Ultrasensitive MRI detection of spontaneous pancreatic tumors with nanocage-based targeted contrast agent.
Pancreatic Neoplasms
Uncovering Differently Expressed Markers and Heterogeneity on Human Pancreatic Cancer.
Pancreatic Neoplasms
Withaferin A targets heat shock protein 90 in pancreatic cancer cells.
Pancreatic Neoplasms
ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells.
Pancreatic Neoplasms
[Pancreatic acinar neoplasms : Comparative molecular characterization].
Pancreatitis
Acute pancreatitis results in induction of heat shock proteins 70 and 27 and heat shock factor-1.
Pancreatitis
Arginine induced acute pancreatitis alters the actin cytoskeleton and increases heat shock protein expression in rat pancreatic acinar cells.
Pancreatitis
Both thermal and non-thermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas.
Pancreatitis
Comparative effects of water immersion pretreatment on three different acute pancreatitis models in rats.
Pancreatitis
Differential induction of HSP60 and HSP72 by different stress situations in rats. Correlation with cerulein-induced pancreatitis.
Pancreatitis
Downregulation of GRP78 and XIAP is correlated with apoptosis during cerulein-induced acute pancreatitis in rats via regulation of caspase activation.
Pancreatitis
Electroacupuncture protects against CCK-induced acute pancreatitis in rats.
Pancreatitis
Extracellular heat-shock protein 70 aggravates cerulein-induced pancreatitis through toll-like receptor-4 in mice.
Pancreatitis
Functional role of J domain of cysteine string protein in Ca2+-dependent secretion from acinar cells.
Pancreatitis
Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute Pancreatitis.
Pancreatitis
Heat shock protein 70 prevents secretagogue-induced cell injury in the pancreas by preventing intracellular trypsinogen activation.
Pancreatitis
Heat shock proteins in pancreatic diseases.
Pancreatitis
High Serum Levels of High-Mobility Group Box 1 (HMGB1) and Low Levels of Heat Shock Protein 70 (Hsp70) are Associated with Poor Prognosis in Patients with Acute Pancreatitis.
Pancreatitis
Hyperlipidemia induced by a cholesterol-rich diet aggravates necrotizing pancreatitis in rats.
Pancreatitis
Hyperthermia induces heat shock protein expression and protection against cerulein-induced pancreatitis in rats.
Pancreatitis
Hypertonic Saline Reduces Metalloproteinase Expression In Liver During Pancreatitis.
Pancreatitis
Induction of a 60-kDa heat shock protein in rat pancreas by water-immersion stress.
Pancreatitis
Induction of heat shock protein and prevention of caerulein-induced pancreatitis by water-immersion stress in rats.
Pancreatitis
Induction of heat shock proteins fails to produce protection against trypsin-induced acute pancreatitis in rats.
Pancreatitis
Induction of HSP72 by sodium arsenite fails to protect against cholecystokinin-octapeptide-induced acute pancreatitis in rats.
Pancreatitis
Ischemic preconditioning inhibits development of edematous cerulein-induced pancreatitis: Involvement of cyclooxygenases and heat shock protein 70.
Pancreatitis
Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury.
Pancreatitis
MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis.
Pancreatitis
NF-kappaB activation is detrimental in arginine-induced acute pancreatitis.
Pancreatitis
Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats.
Pancreatitis
Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis.
Pancreatitis
Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis.
Pancreatitis
Polymorphism of the TNF-alpha, HSP70-2, and CD14 genes increases susceptibility to severe acute pancreatitis.
Pancreatitis
Pre-inhalation of hydrogen-rich gases protect against caerulein-induced mouse acute pancreatitis while enhance the pancreatic Hsp60 protein expression.
Pancreatitis
Prior peritoneal lavage with hot 0.9 % saline induces HSP70 expression and protects against cerulein-induced acute pancreatitis in rats.
Pancreatitis
Regulation of Hsp60 and the role of MK2 in a new model of severe experimental pancreatitis.
Pancreatitis
Regulation of HSP60 and the role of MK2 in a new model of severe experimental pancreatitis.
Pancreatitis
Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma.
Pancreatitis
Simultaneous proteosome inhibition and heat shock protein induction by bortezomib is beneficial in experimental pancreatitis.
Pancreatitis
Sterile inflammatory response in acute pancreatitis.
Pancreatitis
Tethered Lipid Membranes as a Nanoscale Arrangement towards Non-Invasive Analysis of Acute Pancreatitis.
Pancreatitis
The effects of hypo- and hyperthermic pretreatment on sodium taurocholate-induced acute pancreatitis in rats.
Pancreatitis
Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats.
Pancreatitis
Water immersion pretreatment decreases pro-inflammatory cytokine production in cholecystokinin-octapeptide-induced acute pancreatitis in rats: possible role of HSP72.
Pancreatitis
Water immersion stress induces heat shock protein 60 expression and protects against pancreatitis in rats.
Pancreatitis
Water immersion stress induces heat shock protein expression and protects against pancreatitis.
Pancreatitis, Acute Necrotizing
VER-155008 induced Hsp70 proteins expression in fish cell cultures while impeding replication of two RNA viruses.
Pancreatitis, Chronic
Changes in the Expression of Glucose-regulated Protein 78 in the Occurrence and Progression of Pancreatic Cancer in Mouse Models.
Pancreatitis, Chronic
Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma.
Pancreatitis, Chronic
Polymorphisms of the MCP-1 and HSP70-2 genes in Korean patients with alcoholic chronic pancreatitis.
Pancreatitis, Chronic
Proteins Differentially Expressed in the Pancreas of Hepatic Alcohol Dehydrogenase-Deficient Deer Mice Fed Ethanol For 3 Months.
Pancreatitis, Chronic
Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma.
Papilloma
Analysis of HSP90 Expression Is Valuable in the Differential Diagnosis of Ocular Surface Squamous Lesions.
Papilloma
Antisera against Neisseria gonorrhoeae cross-react with specific brain proteins of the common marmoset monkey and other nonhuman primate species.
Papilloma
Nuclear RNA accumulations contain released transcripts and exhibit specific distributions with respect to Sm antigen foci.
Papilloma
The effects of treated effluents on the intensity of papillomatosis and HSP70 expression in roach.
Papilloma, Choroid Plexus
Antisera against Neisseria gonorrhoeae cross-react with specific brain proteins of the common marmoset monkey and other nonhuman primate species.
Papillomavirus Infections
Effect of human papillomavirus infection on estrogen receptor and heat shock protein hsp27 phenotype in human cervix and vagina.
Papillomavirus Infections
Immunohistochemical evaluation of heat shock proteins in normal and preinvasive lesions of the cervix.
Papillomavirus Infections
Technology evaluation: HspE7 (Stressgen).
Paracoccidioidomycosis
A new Paracoccidioides brasiliensis 70-kDa heat shock protein reacts with sera from paracoccidioidomycosis patients.
Paracoccidioidomycosis
Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection.
Paracoccidioidomycosis
Heterologous expression, purification, and immunological reactivity of a recombinant HSP60 from Paracoccidioides brasiliensis.
Paracoccidioidomycosis
Molecular cloning, characterization and expression of the heat shock protein 60 gene from the human pathogenic fungus Paracoccidioides brasiliensis.
Paraganglioma
Diagnosis and surgical treatment of retroperitoneal paraganglioma: A single-institution experience of 34 cases.
Paralysis
Expression of heat shock protein epitopes in tubular aggregates.
Paralysis
Heat shock treatment reduces beta amyloid toxicity in vivo by diminishing oligomers.
Paralysis
Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-? deposition in a mouse model of Alzheimer's disease.
Paralysis
Preoperative stress conditioning prevents paralysis after experimental aortic surgery: increased heat shock protein content is associated with ischemic tolerance of the spinal cord.
Paralysis
The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration.
Paraneoplastic Syndromes, Ocular
Cancer-associated retinopathy induced by both anti-recoverin and anti-hsc70 antibodies in vivo.
Paraneoplastic Syndromes, Ocular
Invasive thymoma with paraneoplastic retinopathy.
Paraneoplastic Syndromes, Ocular
Mechanisms of photoreceptor cell death in cancer-associated retinopathy.
Paraparesis
Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13).
Paraparesis, Spastic
HSP60 is a rare cause of hereditary spastic paraparesis, but may act as a genetic modifier.
Paraplegia
Late onset motoneuron disorder caused by mitochondrial Hsp60 chaperone deficiency in mice.
Paraproteinemias
Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma.
Paraproteinemias
Role of Specific B-Cell Receptor Antigens in Lymphomagenesis.
Paraproteinemias
STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90alpha and beta in multiple myeloma cells, which critically contribute to tumor-cell survival.
Paraproteinemias
Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.
Parasitemia
Susceptibility of heat shock protein 70.1-deficient C57BL/6 J, wild-type C57BL/6 J and A/J mice to Trypanosoma congolense infection.
Parasitic Diseases
17-AAG-Induced Activation of the Autophagic Pathway in Leishmania Is Associated with Parasite Death.
Parasitic Diseases
A Case of Adenomyosis with a High Titer of IgG Autoantibody to Calreticulin.
Parasitic Diseases
A chemical inhibitor of heat shock protein 78 (HSP78) from Leishmania donovani represents a potential antileishmanial drug candidate.
Parasitic Diseases
Hsp90 Inhibitors in Parasitic Nematodes: Prospects and Challenges.
Parasitic Diseases
Identification and characterization of the antiplasmodial activity of Hsp90 inhibitors.
Parasitic Diseases
Repurposing drugs to target the malaria parasite unfolding protein response.
Parasitic Diseases
Targeting Hsp90 in Non-Cancerous Maladies.
Paratuberculosis
Anti Mycobacterium avium subsp. paratuberculosis heat shock protein 70 antibodies in the sera of Sardinian patients with multiple sclerosis.
Paratuberculosis
Complete nucleotide sequence of a gene encoding the 70 kd heat shock protein of Mycobacterium paratuberculosis.
Paratuberculosis
Cytokine gene expression profiles of bovine dendritic cells after interaction with Mycobacterium avium ssp. paratuberculosis (M.a.p.), Escherichia coli (E. coli) or recombinant M.a.p. heat shock protein 70.
Paratuberculosis
Development and use of a partial Mycobacterium avium subspecies paratuberculosis protein array.
Paratuberculosis
Development of DNA-Designed Avian IgY Antibodies for Detection of Mycobacterium avium subsp. paratuberculosis Heat Shock Protein 70 (Hsp70) and Anti-Hsp70 Antibodies in the Serum of Normal Cattle.
Paratuberculosis
Heat shock protein 70 subunit vaccination against bovine paratuberculosis does not interfere with current immunodiagnostic assays for bovine tuberculosis.
Paratuberculosis
Identification and characterization of Mycobacterium paratuberculosis recombinant proteins expressed in E. coli.
Paratuberculosis
Identification of Mycobacterium avium complex in sarcoidosis.
Paratuberculosis
Induction of humoral immunity in response to immunization with recombinant Mycobacterium bovis BCG expressing the S1 subunit of Bordetella pertussis toxin.
Paratuberculosis
M. paratuberculosis Heat Shock Protein 65 and Human Diseases: Bridging Infection and Autoimmunity.
Paratuberculosis
Mycobacteria in the intestine of Japanese patients with inflammatory bowel disease.
Paratuberculosis
Mycobacterium avium ssp. paratuberculosis recombinant heat shock protein 70 interaction with different bovine antigen-presenting cells.
Paratuberculosis
Mycobacterium paratuberculosis heat shock protein 70 as a tool in control of paratuberculosis.
Paratuberculosis
Nucleotide sequence analysis and seroreactivities of the 65K heat shock protein from Mycobacterium paratuberculosis.
Paratuberculosis
Post-exposure subunit vaccination against chronic enteric mycobacterial infection in a natural host.
Paratuberculosis
Rapid differentiation of Mycobacterium avium and M. paratuberculosis by PCR and restriction enzyme analysis.
Parkinson Disease
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
Parkinson Disease
A novel bio-orthogonal cross-linker for improved protein/protein interaction analysis.
Parkinson Disease
Age-dependent accumulation of oligomeric SNCA/?-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
Parkinson Disease
Alternative mitochondrial quality control mediated by extracellular release.
Parkinson Disease
Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease.
Parkinson Disease
Applying Hsp104 to protein-misfolding disorders.
Parkinson Disease
Are heat shock proteins therapeutic target for Parkinson's disease?
Parkinson Disease
Arylsulfatase A, a genetic modifier of Parkinson's disease, is an ?-synuclein chaperone.
Parkinson Disease
Autophagy inhibition rescues structural and functional defects caused by the loss of mitochondrial chaperone Hsc70-5 in Drosophila.
Parkinson Disease
BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.
Parkinson Disease
Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics.
Parkinson Disease
Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model.
Parkinson Disease
CSF Nrf2 and HSPA8 in Parkinson's disease patients with and without LRRK2 gene mutations.
Parkinson Disease
Curcumin Protects an SH-SY5Y Cell Model of Parkinson's Disease Against Toxic Injury by Regulating HSP90.
Parkinson Disease
Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis.
Parkinson Disease
DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats.
Parkinson Disease
DJ-1/PARK7: A New Therapeutic Target for Neurodegenerative Disorders.
Parkinson Disease
Effect of endogenous Hsp104 chaperone in yeast models of sporadic and familial Parkinson's disease.
Parkinson Disease
Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.
Parkinson Disease
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification.
Parkinson Disease
Evaluating the role of ARSA in Chinese patients with Parkinson's disease.
Parkinson Disease
Expression of the human groEL stress-protein homologue in the brain and spinal cord.
Parkinson Disease
Functional Significance of Point Mutations in Stress Chaperone Mortalin and Their Relevance to Parkinson Disease.
Parkinson Disease
Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice.
Parkinson Disease
GRP78 Level Is Altered in the Brain, but Not in Plasma or Cerebrospinal Fluid in Parkinson's Disease Patients.
Parkinson Disease
Heat shock protein 70 reduces ?-synuclein-induced predegenerative neuronal dystrophy in the ?-synuclein viral gene transfer rat model of Parkinson's disease.
Parkinson Disease
Heat shock protein 90 is a potential therapeutic target for ameliorating skeletal muscle abnormalities in Parkinson's disease.
Parkinson Disease
Heat shock protein 90 modulates LRRK2 stability: potential implications for Parkinson's disease treatment.
Parkinson Disease
Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease.
Parkinson Disease
Heat shock proteins in neurodegenerative disorders and aging.
Parkinson Disease
Hsc70 interaction with soluble and fibrillar {alpha}-Synuclein.
Parkinson Disease
Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease.
Parkinson Disease
Hsp104 targets multiple intermediates on the amyloid pathway and suppresses the seeding capacity of Abeta fibrils and protofibrils.
Parkinson Disease
Hsp90 and Its Co-Chaperones in Neurodegenerative Diseases.
Parkinson Disease
HSP90 and Its Novel Co-Chaperones, SGT1 and CHP-1, in Brain of Patients with Parkinson's Disease and Dementia with Lewy Bodies.
Parkinson Disease
Hsp90 Co-chaperone p23 contributes to dopaminergic mitochondrial stress via stabilization of PHD2: Implications for Parkinson's disease.
Parkinson Disease
Human-based studies on alpha-synuclein deposition and relationship to Parkinson's disease symptoms.
Parkinson Disease
Identification of protein interfaces between alpha-synuclein, the principal component of Lewy bodies in Parkinson's disease, and the molecular chaperones human Hsc70 and the yeast Ssa1p.
Parkinson Disease
Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity.
Parkinson Disease
Increased heat shock transcription factor 1 in the cerebellum reverses the deficiency of Purkinje cells in Alzheimer's disease.
Parkinson Disease
Increased Striatal mRNA and Protein Levels of the Immunophilin FKBP-12 in Experimental Parkinson's Disease and Identification of FKBP-12-Binding Proteins.
Parkinson Disease
Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity.
Parkinson Disease
Interactions between Hsp70 and the hydrophobic core of alpha-synuclein inhibit fibril assembly.
Parkinson Disease
Kinetic and structural characterization of human mortalin.
Parkinson Disease
Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson's disease model.
Parkinson Disease
Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain.
Parkinson Disease
Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy.
Parkinson Disease
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10.
Parkinson Disease
Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.
Parkinson Disease
Mechanistic Insights into Hsp104 Potentiation.
Parkinson Disease
miR-16-1 promotes the aberrant ?-synuclein accumulation in parkinson disease via targeting heat shock protein 70.
Parkinson Disease
Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.
Parkinson Disease
Molecular Chaperones as Rational Drug Targets for Parkinson's Disease Therapeutics.
Parkinson Disease
Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress.
Parkinson Disease
Mortalin inhibition in experimental Parkinson's disease.
Parkinson Disease
Mortalin is Expressed by Astrocytes and Decreased in the Midbrain of Parkinson's Disease Patients.
Parkinson Disease
Mortalin mutations are not a frequent cause of early-onset Parkinson disease.
Parkinson Disease
MPTP-induced model of Parkinson's disease in heat shock protein 70.1 knockout mice.
Parkinson Disease
Mutational screening of the mortalin gene (HSPA9) in Parkinson's disease.
Parkinson Disease
Neurodevelopmental defects and neurodegenerative phenotypes in human brain organoids carrying Parkinson's disease-linked DNAJC6 mutations.
Parkinson Disease
Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients.
Parkinson Disease
Protective effect of planarian DJ-1 against 6-hydroxydopamine-induced neurotoxicity.
Parkinson Disease
Proteomic profiling of phosphoproteins and glycoproteins responsive to wild-type alpha-synuclein accumulation and aggregation.
Parkinson Disease
Psychotropics regulate Skp1a, Aldh1a1, and Hspa8 transcription--potential to delay Parkinson's disease.
Parkinson Disease
Purification of hsp104, a protein disaggregase.
Parkinson Disease
Reduced expression of the chaperone-mediated autophagy carrier hsc70 protein in lymphomonocytes of patients with Parkinson's disease.
Parkinson Disease
Serum Mortalin Correlated with ?-Synuclein as Serum Markers in Parkinson's Disease: A Pilot Study.
Parkinson Disease
Silencing of Hsp70 Intensifies 6-OHDA-Induced Apoptosis and Hsp90 Upregulation in PC12 Cells.
Parkinson Disease
Stressing Out Hsp90 in Neurotoxic Proteinopathies.
Parkinson Disease
Structure and function of the molecular chaperone Hsp104 from yeast.
Parkinson Disease
Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases.
Parkinson Disease
The Expression and Release of Hsp60 in 6-OHDA Induced In Vivo and In Vitro Models of Parkinson's Disease.
Parkinson Disease
The interaction of Hsc70 protein with fibrillar ?-Synuclein and its therapeutic potential in Parkinson's disease.
Parkinson Disease
The lysosomal membrane protein LAMP2A promotes autophagic flux and prevents SNCA-induced Parkinson disease-like symptoms in the Drosophila brain.
Parkinson Disease
The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system.
Parkinson Disease
The Molecular Chaperone GRP78/BiP as a Therapeutic Target for Neurodegenerative Disorders: A Mini Review.
Parkinson Disease
The role of thioredoxin-1 in suppression of endoplasmic reticulum stress in Parkinson disease.
Parkinson Disease
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.
Parkinson Disease
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Parkinson Disease
Uncaria rhynchophylla Ameliorates Parkinson's Disease by Inhibiting HSP90 Expression: Insights from Quantitative Proteomics.
Parkinsonian Disorders
Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not ?-synuclein-induced neuronal cell loss.
Parkinsonian Disorders
Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain.
Parkinsonian Disorders
Effects of Exercise and Ferulic Acid on Alpha Synuclein and Neuroprotective Heat Shock Protein 70 in An Experimental Model of Parkinsonism Disease.
Pars Planitis
Peptidic sequence "HSEAETGPP" is recognized by the sera of pars planitis patients.
Pelvic Inflammatory Disease
Antibody response to the chlamydial heat-shock protein 60 in an experimental model of chronic pelvic inflammatory disease in monkeys (Macaca nemestrina).
Pelvic Inflammatory Disease
Antibody to chlamydial hsp60 predicts an increased risk for chlamydial pelvic inflammatory disease.
Pelvic Inflammatory Disease
Chlamydia antibodies, chlamydia heat shock protein, and adverse sequelae after pelvic inflammatory disease: the PID Evaluation and Clinical Health (PEACH) Study.
Pelvic Inflammatory Disease
Chlamydia trachomatis detection in a population of asymptomatic and symptomatic women: correlation with the presence of serological markers for this infection.
Pelvic Inflammatory Disease
Differential human serologic response to two 60,000 molecular weight Chlamydia trachomatis antigens.
Pelvic Inflammatory Disease
Humoral immune response to conserved epitopes of Chlamydia trachomatis and human 60-kDa heat-shock protein in women with pelvic inflammatory disease.
Pelvic Inflammatory Disease
Prevalence and correlates of antibody to chlamydial heat shock protein in women attending sexually transmitted disease clinics and women with confirmed pelvic inflammatory disease.
Pelvic Inflammatory Disease
Reduced levels of gamma-interferon secretion in response to chlamydial 60 kDa heat shock protein amongst women with pelvic inflammatory disease and a history of repeated Chlamydia trachomatis infections.
Pemphigoid, Benign Mucous Membrane
Collagens, collagen-binding heat shock protein 47 and transforming growth factor-beta 1 are induced in cicatricial pemphigoid: possible role(s) in dermal fibrosis.
Pemphigoid, Benign Mucous Membrane
Endoplasmic reticulum stress promotes inflammation-mediated proteolytic activity at the ocular surface.
Pemphigoid, Benign Mucous Membrane
Heat shock protein expression in human conjunctiva.
Pemphigoid, Benign Mucous Membrane
Role of collagen-binding heat shock protein 47 and transforming growth factor-beta1 in conjunctival scarring in ocular cicatricial pemphigoid.
Pemphigoid, Bullous
Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid.
Pemphigoid, Bullous
Autoantibodies to human stress proteins. A survey of various rheumatic and other inflammatory diseases.
Pemphigoid, Bullous
Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis.
Pemphigoid, Bullous
Heat shock protein 90 inhibition: A potential double- or triple-edged sword in the treatment of mucous membrane pemphigoid.
Pemphigoid, Bullous
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Pemphigoid, Bullous
Hsp90 blockade modulates bullous pemphigoid IgG-induced IL-8 production by keratinocytes.
Pemphigoid, Bullous
Sequence homologies between hsp60 and autoantigens.
Pemphigus
Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid.
Pemphigus
Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skin.
Pemphigus
Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis.
Pemphigus
Is there any relationship between polymorphism of Heat Shock Protein 70 genes and Pemphigus foliaceus?
Pemphigus
Pemphigus serum and captopril induce heat shock protein 70 and inducible nitric oxide synthase overexpression, triggering apoptosis in human keratinocytes.
Peptic Ulcer
Role of Heat-Shock Protein (HSP) 70-2 Genotype in Peptic Ulcer in Japanese Population.
Peri-Implantitis
Altered immunolocalization of heat-shock proteins in human peri-implant gingiva.
Periapical Periodontitis
The virulence factor GroEL promotes gelatinase secretion from cells in the osteoblast lineage: Implication for direct crosstalk between bacteria and adult cells.
Pericardial Effusion
Humoral response to mycobacterial heat shock proteins in patients with constrictive pericarditis caused by tuberculosis and its implications for pathogenesis.
Perinatal Death
Aberrant gene expression in organs of bovine clones that die within two days after birth.
Perinatal Death
Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression.
Periodontal Diseases
Construction and characterization of a Porphyromonas gingivalis htpG disruption mutant.
Periodontal Diseases
Epitope mapping of heat shock protein 60 (GroEL) from Porphyromonas gingivalis.
Periodontal Diseases
Evaluation of Salivary Level of Heat Shock Protein 70 in Patients with Chronic Periodontitis.
Periodontal Diseases
Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study.
Periodontal Diseases
Helicobacter pylori and Campylobacter rectus share a common antigen.
Periodontal Diseases
Identification of immunological parameters associated with the alveolar bone level in periodontal patients.
Periodontal Diseases
Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
Periodontal Diseases
Porphyromonas gingivalis heat shock protein vaccine reduces the alveolar bone loss induced by multiple periodontopathogenic bacteria.
Periodontal Diseases
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Periodontal Diseases
Salivary immunoglobulin A directed to oral microbial GroEL in patients with periodontitis and their potential protective role.
Periodontal Diseases
Self-heat shock protein 60 induces tumour necrosis factor-alpha in monocyte-derived macrophage: possible role in chronic inflammatory periodontal disease.
Periodontal Diseases
The GroEL protein of Porphyromonas gingivalis accelerates tumor growth by enhancing endothelial progenitor cell function and neovascularization.
Periodontal Pocket
Putative heat shock protein 70 gene from Actinobacillus actinomycetemcomitans: molecular cloning and sequence analysis of its gene.
Periodontitis
Accumulation of human heat shock protein 60-reactive T cells in the gingival tissues of periodontitis patients.
Periodontitis
Balance of inflammatory response in stable gingivitis and progressive periodontitis lesions.
Periodontitis
Characterization of serum antibody to Actinobacillus actinomycetemcomitans GroEL-like protein in periodontitis patients and healthy subjects.
Periodontitis
Differential regulation of circulating levels of molecular chaperones in patients undergoing treatment for periodontal disease.
Periodontitis
Effect of endoplasmic reticulum stress-induced apoptosis in the role of periodontitis on vascular calcification in a rat model.
Periodontitis
Effects of Initial Periodontal Therapy on Heat Shock Protein 70 Levels in Gingival Crevicular Fluid from Periodontitis Patients.
Periodontitis
Elevated humoral immune response to heat shock protein 60 (hsp60) family in periodontitis patients.
Periodontitis
Epitope mapping of heat shock protein 60 (GroEL) from Porphyromonas gingivalis.
Periodontitis
Fusobacterium nucleatum GroEL induces risk factors of atherosclerosis in human microvascular endothelial cells and ApoE(-/-) mice.
Periodontitis
Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study.
Periodontitis
Humoral immune response to heat shock protein 60 of Aggregatibacter actinomycetemcomitans and cross-reactivity with malondialdehyde acetaldehyde-modified LDL.
Periodontitis
Identification of immunoreactive epitopes of the Porphyromonas gingivalis heat shock protein in periodontitis and atherosclerosis.
Periodontitis
Identification of mono- or poly-specific monoclonal antibody to Porphyromonas gingivalis heat-shock protein 60.
Periodontitis
Identification of T-cell epitopes of Porphyromonas gingivalis heat-shock-protein 60 in periodontitis.
Periodontitis
Immune responses to heat shock protein in Porphyromonas gingivalis-infected periodontitis and atherosclerosis patients.
Periodontitis
Molecular and immunological characterization of a 64-kDa protein of Actinobacillus actinomycetemcomitans.
Periodontitis
Natural Monoclonal Antibody to Oxidized Low-Density Lipoprotein and Aggregatibacter actinomycetemcomitans.
Periodontitis
Pep19 drives epitope spreading in periodontitis and periodontitis-associated autoimmune diseases.
Periodontitis
Periodontopathogen- and host-derived immune response in acute coronary syndrome.
Periodontitis
Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
Periodontitis
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Periodontitis
Relationships between the onset of pustulosis palmaris et plantaris, periodontitis and bacterial heat shock proteins.
Periodontitis
Robust immunoreactivity of teenager sera against peptide 19 from Porphyromonas gingivalis HSP60.
Periodontitis
Salivary immunoglobulin A directed to oral microbial GroEL in patients with periodontitis and their potential protective role.
Periodontitis
Self-heat shock protein 60 induces tumour necrosis factor-alpha in monocyte-derived macrophage: possible role in chronic inflammatory periodontal disease.
Periodontitis
Serum antibodies to Porphyromonas gingivalis chaperone HtpG predict health in periodontitis susceptible patients.
Periodontitis
Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT.
Periodontitis
T-cell clonality to Porphyromonas gingivalis and human heat shock protein 60s in patients with atherosclerosis and periodontitis.
Periodontitis
The immune responses to human and microbial heat shock proteins in periodontal disease with and without coronary heart disease.
Periodontitis
Up-regulation of the endoplasmic reticulum stress-response in periodontal disease.
Periodontitis
[Expression and significance of chemokines CCL21, E-selectins and Hsp90 in periodontal tissues of rats with experimental periodontitis].
Periodontitis
[Serum, oral and gingival fluid levels of heat shock protein-70, cytokines and their autoantibodies by periodontal disease].
Peripheral Arterial Disease
Plasma heat shock protein 27 is associated with coronary artery disease, abdominal aortic aneurysm and peripheral artery disease.
Peripheral Arterial Disease
Serum level of soluble Hsp70 is associated with vascular calcification.
Peripheral Arterial Disease
[Role of chronic infection and heat shock proteins in peripheral arterial disease]
Peripheral Nerve Injuries
Heat shock protein 27: developmental regulation and expression after peripheral nerve injury.
Peripheral Nerve Injuries
Heat shock protein is a key therapeutic target for nerve repair in autoimmune peripheral neuropathy and severe peripheral nerve injury.
Peripheral Nerve Injuries
Mutant HSPB1 overexpression in neurons is sufficient to cause age-related motor neuronopathy in mice.
Peripheral Nervous System Diseases
Characterization of human small heat shock protein HSPB1 ?-crystallin domain localized mutants associated with hereditary motor neuron diseases.
Peripheral Nervous System Diseases
Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.
Peripheral Nervous System Diseases
Heat shock protein 90 inhibitors block the antinociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models.
Peripheral Nervous System Diseases
Heat shock protein is a key therapeutic target for nerve repair in autoimmune peripheral neuropathy and severe peripheral nerve injury.
Peripheral Nervous System Diseases
Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases.
Peripheral Nervous System Diseases
KU-32, a novel drug for diabetic neuropathy, is safe for human islets and improves in vitro insulin secretion and viability.
Peripheral Nervous System Diseases
Physico-chemical properties of R140G and K141Q mutants of human small heat shock protein HspB1 associated with hereditary peripheral neuropathies.
Peripheral Nervous System Diseases
Significance of functional GRP78 polymorphisms in predicting the onset of type 2 diabetic peripheral neuropathy in Chinese population.
Peripheral Nervous System Diseases
Synthesis and evaluation of novologues as C-terminal Hsp90 inhibitors with cytoprotective activity against sensory neuron glucotoxicity.
Peripheral Nervous System Diseases
Targeting the Diabetic Chaperome to Improve Peripheral Neuropathy.
Peritoneal Fibrosis
Antisense oligonucleotides against collagen-binding stress protein HSP47 suppress peritoneal fibrosis in rats.
Peritoneal Fibrosis
Enhanced expression of heat shock protein 47 in rat model of peritoneal fibrosis.
Peritoneal Fibrosis
The kampo medicine daikenchuto inhibits peritoneal fibrosis in mice.
Peritoneal Neoplasms
Impact of hyperthermic intraperitoneal chemotherapy on Hsp27 protein expression in serum of patients with peritoneal carcinomatosis.
Peritonitis
Geranylgeranylacetone attenuates septic diaphragm dysfunction by induction of heat shock protein 70.
Peritonitis
Heat shock protein 72 enhances autophagy as a protective mechanism in lipopolysaccharide-induced peritonitis in rats.
Peritonitis
Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.
Peritonitis
Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice.
Persistent Infection
Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study.
Persistent Infection
Association of uterine and salpingeal fibrosis with chlamydial hsp60 and hsp10 antigen-specific antibodies in Chlamydia-infected koalas.
Persistent Infection
Avidity of anti-P aeruginosa antibodies during chronic infection in patients with cystic fibrosis.
Persistent Infection
Chronic Infections and Atherosclerosis.
Persistent Infection
Cross-reactivity of GroEL antibodies with human heat shock protein 60 and quantification of pathogens in atherosclerosis.
Persistent Infection
Heat shock protein 10 of Chlamydophila pneumoniae induces proinflammatory cytokines through Toll-like receptor (TLR) 2 and TLR4 in human monocytes THP-1.
Persistent Infection
Inhibition of Heat Shock Protein 90 Prevents HIV Rebound.
Persistent Infection
Is chlamydial heat shock protein 60 a risk factor for oncogenesis?
Persistent Infection
Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study.
Persistent Infection
Persistence of Chlamydia pneumoniae in degenerative aortic valve stenosis indicated by heat shock protein 60 homologues.
Persistent Infection
Persistent Chlamydia trachomatis infections resist apoptotic stimuli.
Persistent Infection
Post-exposure subunit vaccination against chronic enteric mycobacterial infection in a natural host.
Persistent Infection
Regulation of Molecular Chaperone GRP78 by Hepatitis B Virus: Control of Viral Replication and Cell Survival.
Persistent Infection
The heat shock response of mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis.
Peste-des-Petits-Ruminants
Autophagy in farm animals: current knowledge and future challenges.
Peste-des-Petits-Ruminants
Selection and validation of suitable reference genes for qPCR gene expression analysis in goats and sheep under Peste des petits ruminants virus (PPRV), lineage IV infection.
Pheochromocytoma
Effect of HSP90 inhibitor in pheochromocytoma PC12 cells: an experimental investigation.
Pheochromocytoma
Effects of geldanamycin on neurite outgrowth-related proteins and kinases in nerve growth factor-differentiated pheochromocytoma 12 cells.
Pheochromocytoma
Enantioselective effect of bifenthrin on antioxidant enzyme gene expression and stress protein response in PC12 cells.
Pheochromocytoma
Erratum to: Effect of HSP90 inhibitor in pheochromocytoma PC12 cells: an experimental investigation.
Pheochromocytoma
Expression and diagnostic relevance of heat shock protein 90 and signal transducer and activator of transcription 3 in malignant pheochromocytoma.
Pheochromocytoma
Glucose-regulated protein 75 overexpression attenuates ionizing radiation-mediated injury in PC12 cells by inducing the expression of topoisomerase II?
Pheochromocytoma
HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma.
Pheochromocytoma
Neural differentiation and the attenuated heat shock response.
Pheochromocytoma
Neuroprotective effect of dipeptide AVP(4-5)-NH2 is associated with nerve growth factor and heat shock protein HSP70.
Pheochromocytoma
NVP-AUY922, a novel HSP90 inhibitor, inhibits the progression of malignant pheochromocytoma in vitro and in vivo.
Pheochromocytoma
Partial rescue of geldanamycin-induced TrkA depletion by a proteasome inhibitor in PC12 cells.
Pheochromocytoma
Supraphysiological doses of performance enhancing anabolic-androgenic steroids exert direct toxic effects on neuron-like cells.
Pheochromocytoma
Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma.
Pheochromocytoma
The HSP90 inhibitor 17-AAG exhibits potent antitumor activity for pheochromocytoma in a xenograft model.
Pheochromocytoma
Withdrawal. HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma.
Photosensitivity Disorders
Induction of Hsp60 by Photofrin-mediated photodynamic therapy.
Phytoplasma Disease
'Candidatus Phytoplasma asteris' Strains Associated with Oil Palm Lethal Wilt in Colombia.
Phytoplasma Disease
Waltheria indica is a New Host of Phytoplasma Belongs to 16SrI-B Subgroup Associated with Virescence Symptoms in China.
Pituitary ACTH Hypersecretion
A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease.
Pituitary ACTH Hypersecretion
Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing's Disease.
Pituitary Neoplasms
Elevated levels of mortalin expression in human brain tumors.
Plague
Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors.
Plague
Taxa-specific heat shock proteins are over-expressed with crowding in the Australian plague locust.
Plant Diseases
GroEL protein from the potential biocontrol agent Rhodopseudomonas palustris enhances resistance to rice blast disease.
Plant Diseases
High throughput virus-induced gene silencing implicates heat shock protein 90 in plant disease resistance.
Plant Diseases
The Noncompetitive Effect of Gambogic Acid Displaces Fluorescence-Labeled ATP but Requires ATP for Binding to Hsp90/HtpG.
Plasmacytoma
The major inducible heat shock protein hsp68 is not required for acquisition of thermal resistance in mouse plasmacytoma cell lines.
Pleural Diseases
Mesothelial cells activate the plasma kallikrein-kinin system during pleural inflammation.
Pneumococcal Infections
DnaJ (hsp40) of Streptococcus pneumoniae is involved in bacterial virulence and elicits a strong natural immune reaction via PI3K/JNK.
Pneumococcal Infections
Immunization with a ZmpB-based protein vaccine could protect against pneumococcal diseases in mice.
Pneumoconiosis
Polymorphisms in Heat-shock Protein 70 Genes Are Associated with Coal Workers' Pneumoconiosis in Southwestern China.
Pneumoconiosis
[Effect of HSP70 gene polymorphism on genetic susceptibility of pneumoconiosis of coal worker]
Pneumonia
Anandamide enhances expression of heat shock protein 72 to protect against ischemia-reperfusion injury in rat heart.
Pneumonia
Antibody response to B cell epitopes of Chlamydia trachomatis 60-kDa heat-shock protein and corresponding mycobacterial and human peptides in infants with chlamydial pneumonitis.
Pneumonia
Differential heat shock gene hsp70-1 response to toxicants revealed by in vivo study of lungs in transgenic mice.
Pneumonia
Effects of repeated Chlamydia pneumoniae inoculations on aortic lipid accumulation and inflammatory response in C57BL/6J mice.
Pneumonia
Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia.
Pneumonia
Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis.
Pneumonia
Heat shock protein 70-2+1267 AA homozygotes have an increased risk of septic shock in adults with community-acquired pneumonia.
Pneumonia
Heat shock response and acute lung injury.
Pneumonia
High GRP78 levels in Covid-19 infection: A case-control study.
Pneumonia
HSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivo.
Pneumonia
Hypertonic saline solution increases the expression of heat shock protein 70 and improves lung inflammation early after reperfusion in a rodent model of controlled hemorrhage.
Pneumonia
Immune responses of a chimaeric protein vaccine containing Mycoplasma hyopneumoniae antigens and LTB against experimental M. hyopneumoniae infection in pigs.
Pneumonia
Induction of infertility by the Chlamydia trachomatis mouse pneumonitis biovar in strains of mice that differ in their response to the 60 kDa heat shock protein.
Pneumonia
Involvement of collagen-binding heat shock protein 47 and procollagen type I synthesis in idiopathic pulmonary fibrosis: contribution of type II pneumocytes to fibrosis.
Pneumonia
Lack of protection in mice and necrotizing bronchointerstitial pneumonia with bronchiolitis in guinea pigs immunized with vaccines directed against the hsp60 molecule of Mycobacterium tuberculosis.
Pneumonia
Long-Term Efficacy and Safety of Immunomodulatory Therapy for Atherosclerosis.
Pneumonia
NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection.
Pneumonia
Oral dosing with multi-antigenic construct induces atheroprotective immune tolerance to individual peptides in mice.
Pneumonia
Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection.
Pneumonia
Structural insights into the formation of oligomeric state by a type I Hsp40 chaperone.
Pneumonia
The sequence of the groES and groEL genes from the mouse pneumonitis agent of Chlamydia trachomatis.
Pneumonia
Ventilator-induced heat shock protein 70 and cytokine mRNA expression in a model of lipopolysaccharide-induced lung inflammation.
Pneumonia, Mycoplasma
Antibody response to GroEL varies in patients with acute Mycoplasma pneumoniae infection.
Pneumonia, Pneumocystis
Development of an RT-PCR on the heat shock protein 70 gene for viability detection of Pneumocystis carinii f. sp. hominis in patients with pneumocystosis and in air sample.
Pneumoperitoneum
Comparison of the stress response in patients undergoing gynecological laparoscopic surgery using carbon dioxide pneumoperitoneum or abdominal wall-lifting methods.
Polycystic Kidney Diseases
Bi-allelic pathogenic variations in DNAJB11 cause Ivemark II syndrome, a renal-hepatic-pancreatic dysplasia.
Polycystic Kidney Diseases
Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.
Polycystic Kidney Diseases
Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
Polycystic Kidney, Autosomal Dominant
Bi-allelic pathogenic variations in DNAJB11 cause Ivemark II syndrome, a renal-hepatic-pancreatic dysplasia.
Polycystic Kidney, Autosomal Dominant
Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD).
Polycystic Kidney, Autosomal Dominant
Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice.
Polycystic Kidney, Autosomal Dominant
Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.
Polycystic Kidney, Autosomal Dominant
Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
Polycystic Ovary Syndrome
Effect of Hsp27 on early embryonic development in the mouse.
Polycystic Ovary Syndrome
Impaired heat shock protein 72 expression in women with polycystic ovary syndrome following a supervised exercise programme.
Polycystic Ovary Syndrome
Serum Heat Shock Protein 70 Concentration in Relation to Polycystic Ovary Syndrome in a Non-Obese Chinese Population.
Polycystic Ovary Syndrome
Stress-induced activation of ovarian heat shock protein 90 in a rat model of polycystic ovary syndrome.
Polycystic Ovary Syndrome
The Role of Heat Shock Protein 90B1 in Patients with Polycystic Ovary Syndrome.
Polycythemia Vera
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.
Polycythemia Vera
Proteomic analysis reveals heat shock protein 70 has a key role in polycythemia Vera.
Polymyalgia Rheumatica
Serum levels of antibodies to Chlamydia pneumoniae and human HSP60 in giant cell arteritis patients.
Polymyositis
A dual role for HSP90 and HSP70 in the inflammatory myopathies: from muscle fiber protection to active invasion by macrophages.
Polymyositis
Autoantibodies to the heat-shock protein hsp90 in systemic lupus erythematosus.
Polymyositis
Heat-shock protein 90 and ubiquitin: developmental regulation during myogenesis.
Polymyositis
[Expression of the heat shock protein 70 in inflammatory myopathies]
Polyneuropathies
Heat shock protein 27 is associated with better nerve function and fewer signs of neuropathy.
Polyomavirus Infections
In vivo and in vitro association of hsc70 with polyomavirus capsid proteins.
Porcine Reproductive and Respiratory Syndrome
Inhibition of HSP90 attenuates porcine reproductive and respiratory syndrome virus production in vitro.
Porcine Reproductive and Respiratory Syndrome
Regulation of iNOS-Derived ROS Generation by HSP90 and Cav-1 in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine Lung Injury.
Pre-Eclampsia
Analysis of Nitroso-Proteomes in Normotensive and Severe Preeclamptic Human Placentas.
Pre-Eclampsia
Assessment of placental and maternal stress responses in patients with pregnancy related complications via monitoring of heat shock protein mRNA levels.
Pre-Eclampsia
Association of elevated serum heat-shock protein 70 concentration with transient hypertension of pregnancy, preeclampsia and superimposed preeclampsia: a case-control study.
Pre-Eclampsia
Changes in serum levels of heat shock protein 70 in preterm delivery and pre-eclampsia.
Pre-Eclampsia
Circulating heat shock protein mRNA profile in gestational hypertension, pre-eclampsia & foetal growth restriction.
Pre-Eclampsia
Consensus strategy in genes prioritization and combined bioinformatics analysis for preeclampsia pathogenesis.
Pre-Eclampsia
Correction: Retraction: Heat Shock Protein 70 Expression Is Spatially Distributed in Human Placenta and Selectively Upregulated during Labor and Preeclampsia.
Pre-Eclampsia
Differential proteomic analysis of highly purified placental cytotrophoblasts in preeclampsia demonstrates a state of increased oxidative stress and reduced cytotrophoblast antioxidant defense.
Pre-Eclampsia
Enhancement of heat shock protein 70 attenuates inducible nitric oxide synthase in preeclampsia complicated with fetal growth restriction.
Pre-Eclampsia
Genomic and proteomic investigation of preeclampsia.
Pre-Eclampsia
GRP78 as a marker of pre-eclampsia: an exploratory study.
Pre-Eclampsia
Heat shock protein 27 expression is spatially distributed in human placenta and selectively regulated during preeclampsia.
Pre-Eclampsia
Heat shock protein 27 in the placentas of women with and without severe preeclampsia.
Pre-Eclampsia
Heat shock protein 70 expression is spatially distributed in human placenta and selectively upregulated during labor and preeclampsia.
Pre-Eclampsia
Heat shock protein 70 is not increased in women with severe preeclampsia.
Pre-Eclampsia
Heat shock protein-70 and 4-hydroxy-2-nonenal adducts in human placental villous tissue of normotensive, preeclamptic and intrauterine growth restricted pregnancies.
Pre-Eclampsia
High levels of heat shock protein 70 are associated with pro-inflammatory cytokines and may differentiate early- from late-onset preeclampsia.
Pre-Eclampsia
HSPA1L rs1061581 polymorphism is associated with the risk of preeclampsia in Han Chinese women.
Pre-Eclampsia
Increased serum heat-shock protein 70 levels reflect systemic inflammation, oxidative stress and hepatocellular injury in preeclampsia.
Pre-Eclampsia
Increased superoxide generation and decreased stress protein Hsp90 expression in human umbilical cord vein endothelial cells (HUVECs) from pregnancies complicated by preeclampsia.
Pre-Eclampsia
Is preeclampsia associated with higher frequency of HSP70 gene polymorphisms?
Pre-Eclampsia
Mechanism of JNK signal regulation by placental HSP70 and HSP90 in endothelial cell during preeclampsia.
Pre-Eclampsia
PP003. Heat shock protein 27 expression is spatially distributed in human placenta and selectively regulated during preeclampsia.
Pre-Eclampsia
Quantification of Calcyclin and Heat Shock Protein 90 in Sera from Women with and without Preeclampsia by Mass Spectrometry.
Pre-Eclampsia
Retraction: Heat Shock Protein 70 Expression Is Spatially Distributed in Human Placenta and Selectively Upregulated during Labor and Preeclampsia.
Pre-Eclampsia
Role of prostate apoptosis response 4 in translocation of GRP78 from the endoplasmic reticulum to the cell surface of trophoblastic cells.
Pre-Eclampsia
Serum heat shock protein 70 in preeclampsia and normal pregnancy: A systematic review and meta-analysis.
Pre-Eclampsia
Serum heat shock protein 70 levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in women with preeclampsia.
Pre-Eclampsia
Serum levels of heat shock protein 70 in patients with preeclampsia: a pilot-study.
Pre-Eclampsia
Serum levels of miR-628-3p and miR-628-5p during the early pregnancy are increased in women who subsequently develop preeclampsia.
Pre-Eclampsia
The role of albumin and endoplasmic reticulum in pathogenesis Preeclampsia. Changes of GRP78 and placental VEGF in preeclampsia.
Pre-Eclampsia
The Role of Melatonin in Oxidative Stress, DNA Damage, Apoptosis and Angiogenesis in Fetal Eye under Preeclampsia and Melatonin Deficiency Stress.
Pre-Eclampsia
[Effect of endoplasmic reticulum stress-responsive protein glucose-regulated protein 78, 94 and endoplasmic reticulum apoptosis factor caspase-12 in trophocyte on the pathogenesis of preeclampsia.]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
17-DMAG disrupted the autophagy flux leading to the apoptosis of acute lymphoblastic leukemia cells by inducing heat shock cognate protein 70.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Correction: Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in Mice.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Differential expression levels of the heat shock protein 27 isoforms in pediatric normal, nonleukemic and common acute lymphoblastic leukemia B-cell precursors.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Diminished phosphorylation of a heat shock protein (HSP 27) in infant acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Effect of heat shock protein-90 (HSP90) and vascular endothelial growth factor (VEGF) on survival in acute lymphoblastic leukemia: an immunohistochemical study.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Expression of heat-shock protein 90 in glucocorticoid-sensitive and -resistant childhood acute lymphoblastic leukaemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
HLA complex-linked heat shock protein genes and childhood acute lymphoblastic leukemia susceptibility.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Hsp90 inhibitor BIIB021 enhances triptolide-induced apoptosis of human T-cell acute lymphoblastic leukemia cells in vitro mainly by disrupting p53-MDM2 balance.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
HSP90 inhibitors decrease AID levels and activity in mice and in human cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Identification of heat shock protein 32 (Hsp32) as a novel target in acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Induction chemotherapy reduces extracellular heat shock protein 72 levels, inflammation, lipoperoxidation and changes insulin sensitivity in children and adolescents newly diagnosed with acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in Mice.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Serum heat shock protein 90 as a future predictive biomarker in childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The synthetic heat shock protein 90 (Hsp90) inhibitor EC141 induces degradation of Bcr-Abl p190 protein and apoptosis of Ph-positive acute lymphoblastic leukemia cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Effect of Heat Shock Protein 90 Inhibitor 17-DMAG on Proliferation and Apoptosis of Acute Lymphocytic Leukemia Cell Line Jurkat].
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Stabilization of Notch1 by the Hsp90 Chaperon is Crucial for T Cell Leukemogenesis.
Pregnancy, Ectopic
Deoxyribonucleic acid of Chlamydia trachomatis in fresh tissue from the Fallopian tubes of patients with ectopic pregnancy.
Pregnancy, Ectopic
Differential human serologic response to two 60,000 molecular weight Chlamydia trachomatis antigens.
Pregnancy, Ectopic
Serological responses of patients with ectopic pregnancy to epitopes of the Chlamydia trachomatis 60 kDa heat shock protein.
Pregnancy, Ectopic
Seropositivity for the human heat shock protein (Hsp)60 accompanying seropositivity for Chlamydia trachomatis is less prevalent among tubal ectopic pregnancy cases than individuals with normal reproductive history.
Pregnancy, Ectopic
Serum interleukin-1?, interleukin-8 and anti-heat shock 60 Chlamydia trachomatis antibodies as markers of ectopic pregnancy.
Premature Birth
Correction: Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth.
Premature Birth
Heat shock proteins and heat shock protein-antibody complexes in placental tissues.
Premature Birth
Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth.
Premature Birth
Preterm birth and/or low birth weight are associated with periodontal disease and the increased placental immunohistochemical expression of inflammatory markers.
Premature Birth
The Preventive Effects of Quercetin on Preterm Birth Based on Network Pharmacology and Bioinformatics.
Premature Birth
Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth.
Presbyopia
Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibility.
Pressure Ulcer
Non-invasive detection of local tissue responses to predict pressure ulcer development in mouse models.
Pressure Ulcer
Prediction of healing in Category I pressure ulcers by skin blotting with plasminogen activator inhibitor 1, interleukin-1?, vascular endothelial growth factor C, and heat shock protein 90?: A pilot study.
Pressure Ulcer
[The expressions of endoplasmic reticulum molecular chaperone proteins in pressure ulcer on the different stage of ischemic injury].
Primary Graft Dysfunction
HSP90 Inhibitor Improves Lung Protection in Porcine Model of Donation after Circulatory Arrest.
Primary Myelofibrosis
Heat shock protein 27 (HSP27/HSPB1) expression is increased in patients with primary and secondary myelofibrosis and may be affecting their survival.
Primary Myelofibrosis
Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage.
Primary Myelofibrosis
The role of calreticulin mutations in myeloproliferative neoplasms.
Prion Diseases
A designer molecular chaperone against transmissible spongiform encephalopathy slows disease progression in mice and macaques.
Prion Diseases
Creutzfeldt-Jakob disease: heat shock protein 70 mRNA levels in mononuclear blood cells and clinical study.
Prion Diseases
Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction.
Prion Diseases
Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).
Prion Diseases
The 14-3-3 protein forms a molecular complex with heat shock protein Hsp60 and cellular prion protein.
Prion Diseases
The chaperone Grp78 in protein folding disorders of the nervous system.
Prion Diseases
The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo.
Prion Diseases
The possible role of protein X, a putative auxiliary factor in pathological prion replication, in regulating a physiological endoproteolytic cleavage of cellular prion protein.
Prostatic Hyperplasia
Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer.
Prostatic Hyperplasia
Expression of Heat Shock Protein 27 in Benign Prostatic Hyperplasia with Chronic Inflammation.
Prostatic Hyperplasia
Heat Shock Protein 90 is Associated with Hyperplasia and Neoplastic Transformation of Canine Prostatic Epithelial Cells.
Prostatic Hyperplasia
Immunohistochemical expression of heat shock proteins, p63 and androgen receptor in benign prostatic hyperplasia and prostatic carcinoma in the dog.
Prostatic Hyperplasia
Molecular classification of benign prostatic hyperplasia: A gene expression profiling study in a rat model.
Prostatic Hyperplasia
Response to sublethal heat treatment of prostatic tumor cells and of prostatic tumor infiltrating T-cells.
Prostatic Intraepithelial Neoplasia
Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer.
Prostatic Neoplasms
17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts.
Prostatic Neoplasms
17-DMCHAG, a new geldanamycin derivative, inhibits prostate cancer cells through Hsp90 inhibition and survivin downregulation.
Prostatic Neoplasms
?-Lapachone Induces NQO1- and Oxidative Stress-Dependent Hsp90 Cleavage and Inhibits Tumor Growth and Angiogenesis.
Prostatic Neoplasms
A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response.
Prostatic Neoplasms
A novel HSP90 inhibitor delays castrate resistant prostate cancer without altering serum PSA levels and inhibits osteoclastogenesis.
Prostatic Neoplasms
A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.
Prostatic Neoplasms
A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers.
Prostatic Neoplasms
A phase II trial of ganetespib, a heat shock protein 90 Hsp90) inhibitor, in patients with docetaxel-pretreated metastatic castrate-resistant prostate cancer (CRPC)-a prostate cancer clinical trials consortium (PCCTC) study.
Prostatic Neoplasms
A randomized phase 2 study of a HSP27 targeting antisense, apatorsen with prednisone versus prednisone alone, in patients with metastatic castration resistant prostate cancer.
Prostatic Neoplasms
Abrogation of heat-shock protein (HSP)70 expression induced cell growth inhibition and apoptosis in human androgen-independent prostate cancer cell line PC-3m.
Prostatic Neoplasms
Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer.
Prostatic Neoplasms
Activated ?2-Macroglobulin Binding to Human Prostate Cancer Cells Triggers Insulin-like Responses.
Prostatic Neoplasms
Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78.
Prostatic Neoplasms
Akt-regulated pathways in prostate cancer.
Prostatic Neoplasms
Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells.
Prostatic Neoplasms
Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers.
Prostatic Neoplasms
Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells.
Prostatic Neoplasms
Apoptosis induction by 1alpha,25-dihydroxyvitamin D3 in prostate cancer.
Prostatic Neoplasms
Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer.
Prostatic Neoplasms
Association of HSP70-hom genetic variant with prostate cancer risk.
Prostatic Neoplasms
Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma.
Prostatic Neoplasms
Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.
Prostatic Neoplasms
Beyond androgen deprivation: ancillary integrative strategies for targeting the androgen receptor addiction of prostate cancer.
Prostatic Neoplasms
Bifunctional Au-templated RNA nanoparticles enable direct cell uptake detection and GRP75 knockdown in prostate cancer.
Prostatic Neoplasms
Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK.
Prostatic Neoplasms
Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.
Prostatic Neoplasms
Bruceantin targets HSP90 to overcome resistance to hormone therapy in castration-resistant prostate cancer.
Prostatic Neoplasms
Cabazitaxel inhibits prostate cancer cell growth by inhibition of androgen receptor and heat shock protein expression.
Prostatic Neoplasms
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production.
Prostatic Neoplasms
Castration-Induced Downregulation of SPARC in Stromal Cells Drives Neuroendocrine Differentiation of Prostate Cancer.
Prostatic Neoplasms
Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells.
Prostatic Neoplasms
Cell surface heat shock protein 90 modulates prostate cancer cell adhesion and invasion through the integrin-?1/focal adhesion kinase/c-Src signaling pathway.
Prostatic Neoplasms
Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells.
Prostatic Neoplasms
Clusterin Inhibition using OGX-011 Synergistically Enhances Hsp90 Inhibitor Activity by Suppressing the Heat Shock Response in Castrate Resistant Prostate Cancer.
Prostatic Neoplasms
Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells.
Prostatic Neoplasms
Co-targeting AR and HSP90 suppresses prostate cancer cell growth and prevents resistance mechanisms.
Prostatic Neoplasms
Codelivery of GRP78 siRNA and docetaxel via RGD-PEG-DSPE/DOPA/CaP nanoparticles for the treatment of castration-resistant prostate cancer.
Prostatic Neoplasms
Colocalisation of CD9 and mortalin in CD9-induced mitotic catastrophe in human prostate cancer cells.
Prostatic Neoplasms
Combined ?-methylacyl-CoA racemase inhibition and docetaxel treatment reduce cell proliferation and decrease expression of heat shock protein 27 in androgen receptor-variant-7-positive prostate cancer cells.
Prostatic Neoplasms
Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors.
Prostatic Neoplasms
Cooperative Interactions between Androgen Receptor (AR) and Heat-Shock Protein 27 Facilitate AR Transcriptional Activity.
Prostatic Neoplasms
Cotargeting HSP90 and Its Client Proteins for Treatment of Prostate Cancer.
Prostatic Neoplasms
CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer.
Prostatic Neoplasms
Cross-presentation of the oncofoetal tumor antigen 5T4 from irradiated prostate cancer cells - a key role for heat shock protein 70 and receptor CD91.
Prostatic Neoplasms
Cytochrome P450 17A1 Inhibitor Abiraterone Acetate Counteracts the Heat Shock Protein 27's Cell Survival Properties in Prostate Cancer Cells.
Prostatic Neoplasms
Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer.
Prostatic Neoplasms
Delivery of HSP90 Inhibitor Using Water Soluble Polymeric Conjugates with High Drug Payload.
Prostatic Neoplasms
Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.
Prostatic Neoplasms
Differences in glycosylation patterns of heat shock protein, gp96: implications for prostate cancer prevention.
Prostatic Neoplasms
Differential expression of Annexin 2, SPINK1, and Hsp60 predict progression of prostate cancer through bifurcated WHO Gleason score categories in African American men.
Prostatic Neoplasms
Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients.
Prostatic Neoplasms
Disruption of an hTERT-mTOR-RAPTOR protein complex by a phytochemical perillyl alcohol and rapamycin.
Prostatic Neoplasms
Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells.
Prostatic Neoplasms
Downregulation of androgen receptors by NaAsO2 via inhibition of AKT-NF-?B and HSP90 in castration resistant prostate cancer.
Prostatic Neoplasms
Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion.
Prostatic Neoplasms
Effect of the heat shock protein HSP27 on androgen receptor expression and function in prostate cancer cells.
Prostatic Neoplasms
Effect of the hsp90 inhibitor geldanamycin on androgen response of prostate cancer under hypoxic conditions.
Prostatic Neoplasms
Effects of dihydroartemisinin on HSP70 expression in human prostate cancer PC-3 cells.
Prostatic Neoplasms
Effects of quercetin on the heat-induced cytotoxicity of prostate cancer cells.
Prostatic Neoplasms
Efficient Delivery of Sticky siRNA and Potent Gene Silencing in a Prostate Cancer Model Using a Generation 5 Triethanolamine-Core PAMAM Dendrimer.
Prostatic Neoplasms
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Prostatic Neoplasms
Enhanced expression of heat shock protein 27 following neoadjuvant hormonal therapy is associated with poor clinical outcome in patients undergoing radical prostatectomy for prostate cancer.
Prostatic Neoplasms
Estrogen receptor gene expression and its relation to the estrogen-inducible HSP27 heat shock protein in hormone refractory prostate cancer.
Prostatic Neoplasms
Evaluation of the radiosensitizing potency of chemotherapeutic agents in prostate cancer cells.
Prostatic Neoplasms
Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors.
Prostatic Neoplasms
Expression levels of heat shock protein 27 and cellular FLICE-like inhibitory protein in prostate cancer correlate with Gleason score sum and pathologic stage.
Prostatic Neoplasms
Expression of Heat Shock Protein 27 in Benign Prostatic Hyperplasia with Chronic Inflammation.
Prostatic Neoplasms
Expression of heat shock protein 27 in prostate cancer cell lines according to the extent of malignancy and doxazosin treatment.
Prostatic Neoplasms
Expression of interleukin-6 is downregulated by 17-(allylamino)-17-demethoxygeldanamycin in human prostatic carcinoma cells.
Prostatic Neoplasms
Expression of major heat shock proteins in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy.
Prostatic Neoplasms
Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancer.
Prostatic Neoplasms
Expression of TRAP1 predicts poor survival of malignant glioma patients.
Prostatic Neoplasms
Fatty Acid Oxidation Is an Adaptive Survival Pathway Induced in Prostate Tumors by HSP90 Inhibition.
Prostatic Neoplasms
Finding the place of histone deacetylase inhibitors in prostate cancer therapy.
Prostatic Neoplasms
FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells.
Prostatic Neoplasms
Formulation and in vitro efficacy of liposomes containing the Hsp90 inhibitor 6BrCaQ in prostate cancer cells.
Prostatic Neoplasms
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function.
Prostatic Neoplasms
Genistein inhibits matrix metalloproteinase type 2 activation and prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway.
Prostatic Neoplasms
Glucose-regulated protein 78 mediates hormone-independent prostate cancer progression and metastasis through maspin and COX-2 expression.
Prostatic Neoplasms
Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells.
Prostatic Neoplasms
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.
Prostatic Neoplasms
GRP78 and ?2-macroglobulin are new promising targets for metastatic castrate-resistant prostate cancer treatment.
Prostatic Neoplasms
GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
Prostatic Neoplasms
GRP78 modulates cell adhesion markers in prostate Cancer and multiple myeloma cell lines.
Prostatic Neoplasms
GRP78 Participates in PCA3-regulated Prostate Cancer Progression.
Prostatic Neoplasms
GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer.
Prostatic Neoplasms
GRP78 up-regulation is associated with androgen receptor status, Hsp70-Hsp90 client proteins and castrate-resistant prostate cancer.
Prostatic Neoplasms
GRP78-targeted nanotherapy against castrate-resistant prostate cancer cells expressing membrane GRP78.
Prostatic Neoplasms
HDAC6 Regulates Androgen Receptor Hypersensitivity and Nuclear Localization via Modulating Hsp90 Acetylation in Castration-Resistant Prostate Cancer.
Prostatic Neoplasms
Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E.
Prostatic Neoplasms
Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer.
Prostatic Neoplasms
Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells.
Prostatic Neoplasms
Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression.
Prostatic Neoplasms
Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells.
Prostatic Neoplasms
Heat shock protein 90 (Hsp90) chaperone complex inhibitor, radicicol, potentiated radiation-induced cell killing in a hormone-sensitive prostate cancer cell line through degradation of the androgen receptor.
Prostatic Neoplasms
Heat shock protein 90 inhibition by 17-allylamino-17- demethoxygeldanamycin: a novel therapeutic approach for treating hormone-refractory prostate cancer.
Prostatic Neoplasms
Heat shock protein expression independently predicts clinical outcome in prostate cancer.
Prostatic Neoplasms
Heat-induced cellular damage and tolerance in combination with adriamycin for the PC-3 prostate cancer cell line: relationships with cytotoxicity, reactive oxygen species and heat shock protein 70 expression.
Prostatic Neoplasms
High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.
Prostatic Neoplasms
HPMA Copolymer-Aminohexylgeldanamycin Conjugates Targeting Cell Surface Expressed GRP78 in Prostate Cancer.
Prostatic Neoplasms
Hsp-27 expression at diagnosis predicts poor clinical outcome in prostate cancer independent of ETS-gene rearrangement.
Prostatic Neoplasms
Hsp27 regulates EGF/?-catenin mediated epithelial to mesenchymal transition in prostate cancer.
Prostatic Neoplasms
Hsp60 and IL-8 axis promotes apoptosis resistance in cancer.
Prostatic Neoplasms
HSP90 and HSP70 are essential for stabilization and activation of the WASF3 metastasis promoting protein.
Prostatic Neoplasms
Hsp90 as a therapeutic target in prostate cancer.
Prostatic Neoplasms
Hsp90 inhibitor 17-AAG inhibits progression of LuCaP35 xenograft prostate tumors to castration resistance.
Prostatic Neoplasms
HSP90 Inhibitor Encapsulated Photo-Theranostic Nanoparticles for Synergistic Combination Cancer Therapy.
Prostatic Neoplasms
Hsp90: Still a viable target in prostate cancer.
Prostatic Neoplasms
Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells.
Prostatic Neoplasms
Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants.
Prostatic Neoplasms
Immediate and transient phosphorylation of the heat shock protein 27 initiates chemoresistance in prostate cancer cells.
Prostatic Neoplasms
Immunization with a recombinant GnRH vaccine conjugated to heat shock protein 65 inhibits tumor growth in orthotopic prostate cancer mouse model.
Prostatic Neoplasms
Immunohistochemical expression of Hsp60 correlates with tumor progression and hormone resistance in prostate cancer.
Prostatic Neoplasms
Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells.
Prostatic Neoplasms
Inhibition of Androgen Receptor Expression with Small Interfering RNA Enhances Cancer Cell Apoptosis by Suppressing Survival Factors in Androgen Insensitive, Late Stage LNCaP Cells.
Prostatic Neoplasms
Inhibition of constitutive and cxc-chemokine-induced NF-kappaB activity potentiates ansamycin-based HSP90-inhibitor cytotoxicity in castrate-resistant prostate cancer cells.
Prostatic Neoplasms
Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone.
Prostatic Neoplasms
Inhibition of Hsp90 augments docetaxel therapy in castrate resistant prostate cancer.
Prostatic Neoplasms
Inhibition of mouse RM-1 prostate cancer and B16F10 melanoma by the fusion protein of HSP65 & STEAP1 186-193.
Prostatic Neoplasms
Inhibition of NF-kappaB1 and NF-kappaB2 activation in prostate cancer cells treated with antibody against the carboxyl terminal domain of GRP78: effect of p53 upregulation.
Prostatic Neoplasms
Insulin-like growth factor-I induces CLU expression through Twist1 to promote prostate cancer growth.
Prostatic Neoplasms
Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells.
Prostatic Neoplasms
Intratumor injection of the Hsp90 inhibitor 17AAG decreases tumor growth and induces apoptosis in a prostate cancer xenograft model.
Prostatic Neoplasms
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Prostatic Neoplasms
KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90? in Prostate Cancer Cells.
Prostatic Neoplasms
Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis.
Prostatic Neoplasms
Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells.
Prostatic Neoplasms
Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen.
Prostatic Neoplasms
LncRNA AC245100.4 binds HSP90 to promote the proliferation of prostate cancer.
Prostatic Neoplasms
Local radiotherapy increases the level of autoantibodies to ribosomal P0 protein but not to heat shock proteins, extracellular matrix molecules and EGFR/ErbB2 receptors in prostate cancer patients.
Prostatic Neoplasms
Loss of cell surface TFII-I promotes apoptosis in prostate cancer cells stimulated with activated ?? -macroglobulin.
Prostatic Neoplasms
Low intensity focused ultrasound (LOFU) modulates unfolded protein response and sensitizes prostate cancer to 17AAG.
Prostatic Neoplasms
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Prostatic Neoplasms
Marchantin M Induces Apoptosis of Prostate Cancer Cells Through Endoplasmic Reticulum Stress.
Prostatic Neoplasms
Mechanisms of disease: the role of heat-shock protein 90 in genitourinary malignancy.
Prostatic Neoplasms
Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line.
Prostatic Neoplasms
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.
Prostatic Neoplasms
Mitochondrial dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in African-American men with prostate cancer.
Prostatic Neoplasms
Mitochondrial Hsp90 chaperones as novel molecular targets in prostate cancer.
Prostatic Neoplasms
Modified biphenyl Hsp90 C-terminal inhibitors for the treatment of cancer.
Prostatic Neoplasms
Modulation of heat-induced cell death in PC-3 prostate cancer cells by the antioxidant inhibitor diethyldithiocarbamate.
Prostatic Neoplasms
Modulation of the unfolded protein response by GRP78 in prostate cancer.
Prostatic Neoplasms
Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78.
Prostatic Neoplasms
Moving Beyond the Androgen Receptor (AR): Targeting AR-Interacting Proteins to Treat Prostate Cancer.
Prostatic Neoplasms
Multi-drug loaded micelles delivering chemotherapy and targeted therapies directed against HSP90 and the PI3K/AKT/mTOR pathway in prostate cancer.
Prostatic Neoplasms
Multicenter Phase II Trial of the Heat Shock Protein 90 Inhibitor, Retaspimycin Hydrochloride (IPI-504), in Patients With Castration-resistant Prostate Cancer.
Prostatic Neoplasms
Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40.
Prostatic Neoplasms
Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity.
Prostatic Neoplasms
NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation.
Prostatic Neoplasms
Non-invasive PET imaging of EGFR degradation induced by a heat shock protein 90 inhibitor.
Prostatic Neoplasms
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells.
Prostatic Neoplasms
Nucleoside-Lipid-Based Nanoparticles for Phenazine Delivery: A New Therapeutic Strategy to Disrupt Hsp27-eIF4E Interaction in Castration Resistant Prostate Cancer.
Prostatic Neoplasms
Optimizing heat shock protein expression induced by prostate cancer laser therapy through predictive computational models.
Prostatic Neoplasms
p53-dependent induction of heat shock protein 27 (HSP27) expression.
Prostatic Neoplasms
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Prostatic Neoplasms
Pharmacodynamic and Clinical Results from a Phase I/II Study of the HSP90 Inhibitor Onalespib in Combination with Abiraterone Acetate in Prostate Cancer.
Prostatic Neoplasms
Phosphorylation of HSP90 by protein kinase A is essential for the nuclear translocation of androgen receptor.
Prostatic Neoplasms
Pifithrin-?, an inhibitor of heat-shock protein 70, can increase the antitumor effects of hyperthermia against human prostate cancer cells.
Prostatic Neoplasms
PIM-1-specific mAb suppresses human and mouse tumor growth by decreasing PIM-1 levels, reducing Akt phosphorylation, and activating apoptosis.
Prostatic Neoplasms
Plasma levels of heat shock protein 70 in patients with prostate cancer: a potential biomarker for prostate cancer.
Prostatic Neoplasms
Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression.
Prostatic Neoplasms
Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer.
Prostatic Neoplasms
Preventive and therapeutic effect of tumor derived heat shock protein, gp96, in an experimental prostate cancer model.
Prostatic Neoplasms
Progression of the role of CRYAB in signaling pathways and cancers.
Prostatic Neoplasms
Prostate cancer serum biomarker discovery through proteomic analysis of alpha-2 macroglobulin protein complexes.
Prostatic Neoplasms
Prostate cancer: Ex vivo efficacy of heat shock protein 90 inhibitors.
Prostatic Neoplasms
Proteomic comparison of prostate cancer cell lines LNCaP-FGC and LNCaP-r reveals heatshock protein 60 as a marker for prostate malignancy.
Prostatic Neoplasms
Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r.
Prostatic Neoplasms
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Prostatic Neoplasms
PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90 and CRM1 in preclinical models of prostate cancer.
Prostatic Neoplasms
Radioactive iodine labeling of monoclonal antibody against Hsp90? and its use in diagnostic imaging in prostate cancer xenograft model.
Prostatic Neoplasms
Re: targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Prostatic Neoplasms
Receptor-recognized ??-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
Prostatic Neoplasms
Regulation of heat shock protein 70-1 expression by androgen receptor and its signaling in human prostate cancer cells.
Prostatic Neoplasms
Role of prostate apoptosis response 4 in translocation of GRP78 from the endoplasmic reticulum to the cell surface of trophoblastic cells.
Prostatic Neoplasms
Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells.
Prostatic Neoplasms
Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity.
Prostatic Neoplasms
Secreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer.
Prostatic Neoplasms
Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors.
Prostatic Neoplasms
Shh Overexpression Is Correlated with GRP78 and AR Expression in Primary Prostate Cancer: Clinicopathological Features and Outcomes in a Chinese Cohort.
Prostatic Neoplasms
Silencing of survivin gene by small interfering RNAs produces supra-additive growth suppression in combination with 17-allylamino-17-demethoxygeldanamycin in human prostate cancer cells.
Prostatic Neoplasms
Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells.
Prostatic Neoplasms
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6.
Prostatic Neoplasms
Suppression of Heat Shock Protein 27 Using OGX-427 Induces Endoplasmic Reticulum Stress and Potentiates Heat Shock Protein 90 Inhibitors to Delay Castrate-resistant Prostate Cancer.
Prostatic Neoplasms
Synergistic enhancement of cancer therapy using a combination of heat shock protein targeted HPMA copolymer-drug conjugates and gold nanorod induced hyperthermia.
Prostatic Neoplasms
Systemic GLIPR1-?TM protein as a novel therapeutic approach for prostate cancer.
Prostatic Neoplasms
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease.
Prostatic Neoplasms
Targeting prostate cancer cells with enzalutamide-HDAC inhibitor hybrid drug 2-75.
Prostatic Neoplasms
Targeting TCTP as a New Therapeutic Strategy in Castration-resistant Prostate Cancer.
Prostatic Neoplasms
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Prostatic Neoplasms
The 70 kilodalton heat shock protein is an inhibitor of apoptosis in prostate cancer.
Prostatic Neoplasms
The androgen receptor antagonist enzalutamide induces apoptosis, dysregulates the heat shock protein system, and diminishes the androgen receptor and estrogen receptor ?1 expression in prostate cancer cells.
Prostatic Neoplasms
The co-chaperone p23 promotes prostate cancer motility and metastasis.
Prostatic Neoplasms
The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90.
Prostatic Neoplasms
The Escherichia coli Subtilase Cytotoxin A Subunit Specifically Cleaves Cell-Surface GRP78 and Abolishes COOH-Terminal-Dependent Signaling.
Prostatic Neoplasms
The heat shock protein 70 inhibitor VER155008 suppresses the expression of HSP27, HOP and HSP90? and the androgen receptor, induces apoptosis, and attenuates prostate cancer cell growth.
Prostatic Neoplasms
The heat shock protein 90 inhibitor, (-)-epigallocatechin gallate, has anticancer activity in a novel human prostate cancer progression model.
Prostatic Neoplasms
The HSP90 inhibitor 17-PAG effectively inhibits the proliferation and migration of androgen-independent prostate cancer cells.
Prostatic Neoplasms
The Hsp90 inhibitor, 17-AAG, prevents the ligand-independent nuclear localization of androgen receptor in refractory prostate cancer cells.
Prostatic Neoplasms
The monomeric receptor binding domain of tetrameric ?2-macroglobulin binds to cell surface GRP78 triggering equivalent activation of signaling cascades.
Prostatic Neoplasms
The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer.
Prostatic Neoplasms
The role of heat shock protein 70 in the thermoresistance of prostate cancer cell line spheroids.
Prostatic Neoplasms
The Role of Prostate Apoptosis Response-4 (Par-4) in Mycobacterium tuberculosis Infected Macrophages.
Prostatic Neoplasms
Thermally Induced Apoptosis, Necrosis, and Heat Shock Protein Expression in 3D Culture.
Prostatic Neoplasms
Transcription factor TFII-I causes transcriptional upregulation of GRP78 synthesis in prostate cancer cells.
Prostatic Neoplasms
Transgenic Expression of the Mitochondrial Chaperone TNFR-associated Protein 1 (TRAP1) Accelerates Prostate Cancer Development.
Prostatic Neoplasms
TRAP1 Regulates Proliferation, Mitochondrial Function and has Prognostic Significance in NSCLC.
Prostatic Neoplasms
TRIB1 Supports Prostate Tumorigenesis and Tumor-Propagating Cell Survival by Regulation of Endoplasmic Reticulum Chaperone Expression.
Prostatic Neoplasms
Tumor secreted Hsp90 subverts Polycomb function to drive prostate tumor growth and invasion.
Prostatic Neoplasms
Ultrasound Targeted Microbubble Destruction for Novel Dual Targeting of HSP72 and HSC70 in Prostate Cancer.
Prostatic Neoplasms
Ultrasound-targeted microbubble destruction combined with dual targeting of HSP72 and HSC70 inhibits HSP90 function and induces extensive tumor-speci?c apoptosis.
Prostatic Neoplasms
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1.
Prostatic Neoplasms
Words of wisdom. Re: Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
Prostatic Neoplasms
[Antisense oligodeoxynucleotide therapy for castration-resistant prostate cancer].
Prostatic Neoplasms
[Effect of quercetin on heat shock protein 27 expression in prostate cancer cells].
Prostatic Neoplasms
[FAK/c-Src signaling pathway mediates the expression of cell surface HSP90 in cultured human prostate cancer cells and its association with their invasive capability].
Prostatitis
Chlamydia trachomatis Infection Is Related to Poor Semen Quality in Young Prostatitis Patients.
Prostatitis
Heat shock protein 9-mediated inflammation reaction in patients with chronic prostatitis with erectile dysfunction.
Prostatitis
Heat-shock protein 70 expression in the seminal plasma of patients with chronic bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome.
Prostatitis
The diagnostic value of urine heat shock protein 70 and prostatic exosomal protein in chronic prostatitis.
Prostatitis
[Levels of cytokines and heat-shock protein 70 in the seminal plasma of patients with chronic bacterial prostatitis and chronic prostatitis/chronic pelvic pain syndrome].
protein kinase c deficiency
Loss of PKC-delta alters cardiac metabolism.
Proteinuria
Correlations of podocyte injury with glucose regulated protein 78 expression and proteinuria in patients with diabetic nephropathy.
Proteinuria
Endoplasmic Reticulum Stress Predicts Clinical Response to Cyclosporine Treatment in Primary Membranous Nephropathy.
Proteinuria
Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal.
Proteinuria
Mizoribine corrects defective nephrin biogenesis by restoring intracellular energy balance.
Proteinuria
The nephroprotection exerted by curcumin in maleate-induced renal damage is associated with decreased mitochondrial fission and autophagy.
Proteinuria
Visualizing tubular lipid peroxidation in intact renal tissue in hypertensive rats.
Proteostasis Deficiencies
A model in which heat shock protein 90 targets protein-folding clefts: Rationale for a new approach to neuroprotective treatment of protein folding diseases.
Proteostasis Deficiencies
Approaches for defining the Hsp90-dependent proteome.
Proteostasis Deficiencies
ER chaperone-metal interactions: Links to protein folding disorders.
Proteostasis Deficiencies
Hsp70:CHIP Ubiquitinates Dysfunctional but Not Native Neuronal NO Synthase.
Proteostasis Deficiencies
Identification of bilateral changes in TID1 expression in the 6-OHDA rat model of Parkinson's disease.
Proteostasis Deficiencies
Structure and function of the molecular chaperone Hsp104 from yeast.
Proteostasis Deficiencies
The chaperone Grp78 in protein folding disorders of the nervous system.
protoporphyrin ferrochelatase deficiency
GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich Ataxia cellular models.
Protozoan Infections
Heat shock protein 90 as a drug target against protozoan infections: Biochemical characterization of Hsp90 from Plasmodium falciparum, Trypanosoma evansi and evaluation of its inhibitor as a candidate drug.
Pruritus
Oxymatrine ameliorates imiquimod-induced psoriasis pruritus and inflammation through inhibiting heat shock protein 90 and heat shock protein 60 expression in keratinocytes.
Pseudorabies
Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5.
Psoriasis
Activation of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91 during induction of psoriasis.
Psoriasis
Antibodies to mycobacterial 65-kDa heat shock protein and other immunodominant antigens in patients with psoriasis.
Psoriasis
Antibodies to the 90 kDa heat shock protein in chronic plaque psoriasis.
Psoriasis
Comparison of expression of heat-shock protein 60, Toll-like receptors 2 and 4, and T-cell receptor gammadelta in plaque and guttate psoriasis.
Psoriasis
Debio 0932, A New Oral Hsp90 Inhibitor, Alleviates Psoriasis in a Xenograft Transplantation Model.
Psoriasis
Effect of alterations in apoptotic pathway on development of metabolic syndrome in patients with psoriasis vulgaris.
Psoriasis
Effects of luteolin on treatment of psoriasis by repressing HSP90.
Psoriasis
Expression of heat shock protein 72 on peripheral blood mononuclear cells from patients with pustulosis palmaris et plantaris.
Psoriasis
Ezrin, maspin, peroxiredoxin 2, and heat shock protein 27: potential targets of a streptococcal-induced autoimmune response in psoriasis.
Psoriasis
Hsp72 antigen expression in the proliferative compartment of involved psoriatic epidermis.
Psoriasis
Increased expression of heat shock protein 90 in keratinocytes and mast cells in patients with psoriasis.
Psoriasis
Linking phenotypes and modes of action through high-content screen fingerprints.
Psoriasis
Oxymatrine ameliorates imiquimod-induced psoriasis pruritus and inflammation through inhibiting heat shock protein 90 and heat shock protein 60 expression in keratinocytes.
Psoriasis
Relationships between the onset of pustulosis palmaris et plantaris, periodontitis and bacterial heat shock proteins.
Psoriasis
Structure-based drug designing and identification of Woodfordia fruticosa inhibitors targeted against heat shock protein (HSP70-1) as suppressor for Imiquimod-induced psoriasis like skin inflammation in mice model.
Psoriasis
Structure-Based Drug Designing and Simulation Studies for Finding Novel Inhibitors of Heat Shock Protein (HSP70) as Suppressors for Psoriasis.
Psoriasis
The HSP90 inhibitor RGRN-305 exhibits strong immunomodulatory effects in human keratinocytes.
Psoriasis
The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.
Pterygium
?ypoxia-inducible factor-1?, von Hippel-Lindau protein, and heat shock protein expression in ophthalmic pterygium and normal conjunctiva.
Pterygium
Immunohistochemical detection of heat shock protein 27 and Ki-67 in human pterygium.
Pterygium
Immunohistochemical detection of Hsp90 and Ki-67 in pterygium.
Pulmonary Arterial Hypertension
Inhibition of heat shock protein 90 improves pulmonary arteriole remodeling in pulmonary arterial hypertension.
Pulmonary Arterial Hypertension
Lessons from Cancer: Subcellular Drug Targeting of Mitochondrial Hsp90 in Pulmonary Arterial Hypertension.
Pulmonary Arterial Hypertension
Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
Pulmonary Arterial Hypertension
New Insights Into Heat Shock Protein 90 in the Pathogenesis of Pulmonary Arterial Hypertension.
Pulmonary Disease, Chronic Obstructive
Active ingredients targeting Nrf2 in the Mongolian medicine Qiwei Putao powder: Systematic pharmacological prediction and validation for chronic obstructive pulmonary disease treatment.
Pulmonary Disease, Chronic Obstructive
Analysis of the Plasma Proteome in COPD: Novel Low Abundance Proteins Reflect the Severity of Lung Remodeling.
Pulmonary Disease, Chronic Obstructive
Association of hsp70-2 (+1267A/G), hsp70-hom (+2437T/C), HMOX-1 (number of GT repeats) and TNF-alpha (+489G/A) polymorphisms with COPD in Croatian population.
Pulmonary Disease, Chronic Obstructive
Association of Plasma Heat Shock Protein 70 with Disease Severity, Smoking and Lung Function of Patients with Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Combination of Systemic Inflammatory Biomarkers in Assessment of Chronic Obstructive Pulmonary Disease: Diagnostic Performance and Identification of Networks and Clusters.
Pulmonary Disease, Chronic Obstructive
Convergent sets of data from in vivo and in vitro methods point to an active role of Hsp60 in chronic obstructive pulmonary disease pathogenesis.
Pulmonary Disease, Chronic Obstructive
Differential DAMP release was observed in the sputum of COPD, asthma and asthma-COPD overlap (ACO) patients.
Pulmonary Disease, Chronic Obstructive
Elevated HSP27, HSP70 and HSP90 alpha in chronic obstructive pulmonary disease: markers for immune activation and tissue destruction.
Pulmonary Disease, Chronic Obstructive
Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium.
Pulmonary Disease, Chronic Obstructive
Fractional heat shock protein 27 urine excretion as a short-term predictor in acute exacerbation of chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Glucose-Regulated Protein 78 Autoantibodies Are Associated with Carotid Atherosclerosis in Chronic Obstructive Pulmonary Disease Patients.
Pulmonary Disease, Chronic Obstructive
Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure.
Pulmonary Disease, Chronic Obstructive
Heat shock protein 27 and cyclophilin A associate with the pathogenesis of COPD.
Pulmonary Disease, Chronic Obstructive
Heat shock protein 27 as a predictor of prognosis in patients admitted to hospital with acute COPD exacerbation.
Pulmonary Disease, Chronic Obstructive
Heat shock protein 70 gene polymorphisms in Han nationality of China with chronic obstructive pulmonary diseases.
Pulmonary Disease, Chronic Obstructive
HSP60 activity on human bronchial epithelial cells.
Pulmonary Disease, Chronic Obstructive
Hsp60 and Hsp10 down-regulation predicts bronchial epithelial carcinogenesis in smokers with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
HSP90AA1, ADRB2, TBL1XR1 and HSPB1 are chronic obstructive pulmonary disease-related genes that facilitate squamous cell lung cancer progression.
Pulmonary Disease, Chronic Obstructive
Increased expression of heat shock protein 70 in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Increased HSP70 and TLR2 Gene Expression and Association of HSP70 rs6457452 Single Nucleotide Polymorphism with the Risk of Chronic Obstructive Pulmonary Disease in the Croatian Population.
Pulmonary Disease, Chronic Obstructive
Increased serum levels of HSP27 as a marker for incipient chronic obstructive pulmonary disease in young smokers.
Pulmonary Disease, Chronic Obstructive
Interleukin-1? drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD.
Pulmonary Disease, Chronic Obstructive
Nuclear HSP90 and HSP70 in COPD patients treated with formoterol or formoterol and corticosteroids.
Pulmonary Disease, Chronic Obstructive
Pathogen-associated molecular patterns and extracellular Hsp70 interplay in NLRP3 inflammasome activation in monocytic and bronchial epithelial cellular models of COPD exacerbations.
Pulmonary Disease, Chronic Obstructive
Protective Role of Genetic Variants in HSP90 Genes-Complex in COPD Secondary to Biomass-Burning Smoke Exposure and Non-Severe COPD Forms in Tobacco Smoking Subjects.
Pulmonary Disease, Chronic Obstructive
Reduced heat shock protein 70 in airway smooth muscle in patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers.
Pulmonary Disease, Chronic Obstructive
Serendipity and technical considerations for the measurement of serum heat shock protein HSP27 in patients with COPD and lung cancer.
Pulmonary Disease, Chronic Obstructive
Serum Heat Shock Protein Levels and the Relationship of Heat Shock Proteins with Various Parameters in Chronic Obstructive Pulmonary Disease Patients.
Pulmonary Disease, Chronic Obstructive
Steroid resistance in COPD is associated with impaired molecular chaperone Hsp90 expression by pro-inflammatory lymphocytes.
Pulmonary Disease, Chronic Obstructive
[DNA damage in lymphocytes from patients with chronic obstructive pulmonary disease]
Pulmonary Disease, Chronic Obstructive
[Relationship between dust exposure and chronic obstructive pulmonary diseases and heat shock protein 72 and 73 in lymphocytes among coal miners]
Pulmonary Edema
Changes in Expressions of HSP27, HSP70, and Soluble Glycoprotein in Heart Failure Rats Complicated with Pulmonary Edema and Correlations with Cardiopulmonary Functions.
Pulmonary Edema
Experimental chronic kidney disease attenuates ischemia-reperfusion injury in an ex vivo rat lung model.
Pulmonary Edema
High-altitude pulmonary edema can be prevented by heat shock protein 70-mediated hyperbaric oxygen preconditioning.
Pulmonary Edema
HSP-70-Mediated Hyperbaric Oxygen Reduces Brain and Pulmonary Edema and Cognitive Deficits in Rats in a Simulated High-Altitude Exposure.
Pulmonary Edema
Inhaled hydrogen sulfide protects against ventilator-induced lung injury.
Pulmonary Embolism
Assessment of heat shock proteins and endothelial dysfunction in acute pulmonary embolism.
Pulmonary Embolism
Hsp90 mediates the balance of nitric oxide and superoxide anion in the lungs of rats with acute pulmonary thromboembolism.
Pulmonary Fibrosis
Alpha-defensin enhances expression of HSP47 and collagen-1 in human lung fibroblasts.
Pulmonary Fibrosis
Antisense oligonucleotide inhibition of heat shock protein (HSP) 47 improves bleomycin-induced pulmonary fibrosis in rats.
Pulmonary Fibrosis
Bleomycin-induced pulmonary fibrosis in rat is associated with increased expression of collagen-binding heat shock protein (HSP) 47.
Pulmonary Fibrosis
Blockade of extracellular heat shock protein 90 alpha by 1G6-D7 attenuates pulmonary fibrosis through inhibiting ERK signaling.
Pulmonary Fibrosis
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.
Pulmonary Fibrosis
GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis.
Pulmonary Fibrosis
Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis.
Pulmonary Fibrosis
Heat Shock Protein 27 Plays a Pivotal Role in Myofibroblast Differentiation and in the Development of Bleomycin-Induced Pulmonary Fibrosis.
Pulmonary Fibrosis
Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice.
Pulmonary Fibrosis
HSP90 Inhibition and Modulation of the Proteome: Therapeutical Implications for Idiopathic Pulmonary Fibrosis (IPF).
Pulmonary Fibrosis
Hsp90 regulation of fibroblast activation in pulmonary fibrosis.
Pulmonary Fibrosis
Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis.
Pulmonary Fibrosis
Introduction of antisense oligonucleotides to heat shock protein 47 prevents pulmonary fibrosis in lipopolysaccharide-induced pneumopathy of the rat.
Pulmonary Fibrosis
JAK1-dependent transphosphorylation of JAK2 limits the antifibrotic effects of selective JAK2 inhibitors on long-term treatment.
Pulmonary Fibrosis
Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis.
Pulmonary Fibrosis
Post-treatment with a heat shock protein 90 inhibitor prevents chronic lung injury and pulmonary fibrosis, following acute exposure of mice to HCl.
Pulmonary Fibrosis
Retraction notice to "Introduction of antisense oligonucleotides to Heat Shock Protein 47 prevents pulmonary fibrosis in lipopolysaccharide-induced pneumopathy of the rat" [Eur. J. Pharmacol. 564/1-3 (2007) 174-180].
Pulmonary Fibrosis
Role of heat shock protein 60 (HSP60) on paraquat intoxication.
Pulmonary Fibrosis
Simvastatin impairs the induction of pulmonary fibrosis caused by a western style diet: a preliminary study.
Pulmonary Fibrosis
Suppression of expression of heat shock protein 70 by gefitinib and its contribution to pulmonary fibrosis.
Pulmonary Fibrosis
The HSP90 Inhibitor, AUY-922, Ameliorates the Development of Nitrogen Mustard-Induced Pulmonary Fibrosis and Lung Dysfunction in Mice.
Pulmonary Fibrosis
[Expression of heat shock protein 70 in lung and plasma of rats with pulmonary fibrosis induced by SiO2].
Purpura
A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase.
Purpura
Heat shock protein 70-2 and tumor necrosis factor-? gene polymorphisms in Chinese children with Henoch-Schönlein purpura.
Purpura
Toll-like receptors 2 and 4 cell surface expression reflects endotoxin tolerance in Henoch-Schönlein purpura.
Purpura, Thrombocytopenic, Idiopathic
Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura.
Purpura, Thrombocytopenic, Idiopathic
Significant reductions in apoptosis-related proteins (HSPA6, HSPA8, ITGB3, YWHAH, and PRDX6) are involved in immune thrombocytopenia.
Purpura, Thrombocytopenic, Idiopathic
[Relationship between the expressions of glucocorticoid receptors ?, ?, ?, p and heat shock protein 90 mRNA in patients with primary immune thrombocytopenia resistant to the glucocorticoid].
Q Fever
Efficient activation of T cells by human monocyte-derived dendritic cells (HMDCs) pulsed with Coxiella burnetii outer membrane protein Com1 but not by HspB-pulsed HMDCs.
Q Fever
Evaluation of the recombinant Heat shock protein B (HspB) of Coxiella burnetii as a potential antigen for immunodiagnostic of Q fever in goats.
Q Fever
In the Search of Potential Serodiagnostic Proteins to Discriminate Between Acute and Chronic Q Fever in Humans. Some Promising Outcomes.
Q Fever
[COMPARISON OF DIAGNOSTIC EFFECTIVENESS OF METHODS OF DETECTION OF COXIELLA BURNETII IN BLOOD OF PATIENTS WITH Q FEVER BASED ON AMPLIFI- CATION OF 16S rRNA GENE FRAGMENTS (STANDARD PCR) AND groEL GENE (REAL- TIME PCR)].
Rabies
Identification of heat shock protein 70 in the rabies virion.
Rabies
Rabies viruses leader RNA interacts with host Hsc70 and inhibits virus replication.
Radiation Fibrosis Syndrome
Sodium tanshinone IIA sulfonate attenuates radiation-induced fibrosis damage in cardiac fibroblasts.
Radiculopathy
Preconditioning crush increases the survival rate of motor neurons after spinal root avulsion.
Raynaud Disease
Modulation of ?(2C) adrenergic receptor temperature-sensitive trafficking by HSP90.
Rectal Neoplasms
Deciphering the Inhibition Mechanism of under Trial Hsp90 Inhibitors and Their Analogues: A Comparative Molecular Dynamics Simulation.
Rectal Neoplasms
GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer.
Rectal Neoplasms
Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer.
Relapsing Fever
Differentiation Borrelia Species in Environmental Samples with High-Resolution DNA Melting Analysis.
Relapsing Fever
Molecular characterization of 'Candidatus Borrelia tachyglossi' (family Spirochaetaceae) in echidna ticks, Bothriocroton concolor.
Renal Insufficiency
Expression of 90-kDa heat shock protein within regenerative tubular cells in a patient with acute oliguric renal failure due to malignant hypertension.
Renal Insufficiency
Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal.
Renal Insufficiency
Oxidative stress and cellular stress response in diabetic nephropathy.
Renal Insufficiency, Chronic
Association of polymorphisms of THBS2 and HSPA8 with hypertension in Japanese individuals with chronic kidney disease.
Renal Insufficiency, Chronic
The heat shock protein profile in children with chronic kidney disease.
Renal Insufficiency, Chronic
The Ratio of Osteoprotegerin to Fetuin-A Is Independently Associated with Vascular Stiffness in Hemodialysis Patients.
Reoviridae Infections
Targeting Heat Shock Protein 70 as an antiviral strategy against grass carp reovirus infection.
Reperfusion Injury
Anandamide enhances expression of heat shock protein 72 to protect against ischemia-reperfusion injury in rat heart.
Reperfusion Injury
Benefit of HSP90? intervention on ischemia-reperfusion injury of venous blood-congested flaps.
Reperfusion Injury
Calpain-mediated Hsp70.1 cleavage in hippocampal CA1 neuronal death.
Reperfusion Injury
Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys.
Reperfusion Injury
Differential expression of heat shock proteins 70-1 and 70-2 mRNA after ischemia-reperfusion injury of rat kidney.
Reperfusion Injury
Down-regulation of GRP78 enhances apoptosis via CHOP pathway in retinal ischemia-reperfusion injury.
Reperfusion Injury
During ischemia-reperfusion in rat kidneys, heat shock response is not regulated by expressional changes of heat shock factor 1.
Reperfusion Injury
Ecto-5'-nucleotidase plays a role in the cardioprotective effects of heat shock protein 72 in ischemia-reperfusion injury in rat hearts.
Reperfusion Injury
Effects of acupuncture at Baihui (DU20) and Zusanli (ST36) on the expression of heat shock protein 70 and tumor necrosis factor ? in the peripheral serum of cerebral ischemia-reperfusion-injured rats.
Reperfusion Injury
Effects of geranyl-geranyl-acetone administration before heat shock preconditioning for conferring tolerance against ischemia-reperfusion injury in rat livers.
Reperfusion Injury
Ergothioneine modulates proinflammatory cytokines and heat shock protein 70 in mesenteric ischemia and reperfusion injury.
Reperfusion Injury
Ergothioneine pretreatment protects the liver from ischemia-reperfusion injury caused by increasing hepatic heat shock protein 70.
Reperfusion Injury
Evaluation of warm ischemia-reperfusion injury using heat shock protein in the rat liver.
Reperfusion Injury
Gene therapy for myocardial protection: transfection of donor hearts with heat shock protein 70 gene protects cardiac function against ischemia-reperfusion injury.
Reperfusion Injury
Gene transfer of heat shock protein 70 protects lung grafts from ischemia-reperfusion injury.
Reperfusion Injury
Geranylgeranylacetone attenuates cerebral ischemia-reperfusion injury in rats through the augmentation of HSP 27 phosphorylation: a preliminary study.
Reperfusion Injury
Geranylgeranylacetone protects against cerebral ischemia and reperfusion injury: HSP90 and eNOS phosphorylation involved.
Reperfusion Injury
Heat shock protein 70 gene transfection protects mitochondrial and ventricular function against ischemia-reperfusion injury.
Reperfusion Injury
Heat shock protein 70 gene transfection protects rat myocardium cell against anoxia-reoxygeneration injury.
Reperfusion Injury
Heat shock protein 70 induced by heat stress protects heterotopically transplanted hearts in rats.
Reperfusion Injury
Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis.
Reperfusion Injury
Heat shock protein 70: A promising therapeutic target for myocardial ischemia-reperfusion injury.
Reperfusion Injury
Heat shock protein 72 enhances manganese superoxide dismutase activity during myocardial ischemia-reperfusion injury, associated with mitochondrial protection and apoptosis reduction.
Reperfusion Injury
Heat shock protein 90 inhibition abrogates TLR4-mediated NF-?B activity and reduces renal ischemia-reperfusion injury.
Reperfusion Injury
Heat shock protein 90-binding agents protect renal cells from oxidative stress and reduce kidney ischemia-reperfusion injury.
Reperfusion Injury
Heat shock protein expression is highly sensitive to ischemia-reperfusion injury in rat kidneys.
Reperfusion Injury
Human heat shock protein 27 exacerbates ischemia reperfusion injury in rats by reducing the number of T regulatory cells.
Reperfusion Injury
Human heat shock protein 27 overexpressing mice are protected against hepatic ischemia and reperfusion injury.
Reperfusion Injury
Hydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress.
Reperfusion Injury
Hypoxia and fetal heart development.
Reperfusion Injury
In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat.
Reperfusion Injury
Induction of heat shock protein 70 and preconditioning by sevoflurane: a potent protective interaction against myocardial ischemia-reperfusion injury.
Reperfusion Injury
Induction of heme oxygenase-1 in kidneys during ex vivo warm perfusion.
Reperfusion Injury
Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte NF-?B/NLRP3 inflammasome pathway : HSPA8 inhibition protects spinal ischemia-reperfusion injury.
Reperfusion Injury
Insulin-induced myocardial protection in isolated ischemic rat hearts requires p38 MAPK phosphorylation of Hsp27.
Reperfusion Injury
Intracellular and extracellular expression of the major inducible 70kDa heat shock protein in experimental ischemia-reperfusion injury of the spinal cord.
Reperfusion Injury
Ischemic preconditioning of the liver in rats: implications of heat shock protein induction to increase tolerance of ischemia-reperfusion injury.
Reperfusion Injury
Lipopolysaccharide pretreatment attenuates myocardial infarct size: A possible mechanism involving heat shock protein 70-inhibitory kappaBalpha complex and attenuation of nuclear factor kappaB.
Reperfusion Injury
Mice that overexpress human heat shock protein 27 have increased renal injury following ischemia reperfusion.
Reperfusion Injury
Mitochondrial import of PKCepsilon is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury.
Reperfusion Injury
Modulation of Poly(ADP-Ribose) Polymerase-1 (PARP-1)-Mediated Oxidative Cell Injury by Ring Finger Protein 146 (RNF146) in Cardiac Myocytes.
Reperfusion Injury
Myocardial protection using an omega-3 fatty acid infusion: quantification and mechanism of action.
Reperfusion Injury
Oral administration of Lactobacillus induces cardioprotection.
Reperfusion Injury
Overexpressed heat shock protein 70 attenuates hypoxic injury in coronary endothelial cells.
Reperfusion Injury
Oxymatrine on Hsp90a expression and apoptosis in a model of lung ischemia-reperfusion injury.
Reperfusion Injury
Preconditioned somatothermal stimulation on median nerve territory increases myocardial heat shock protein 70 and protects rat hearts against ischemia-reperfusion injury.
Reperfusion Injury
Preconditioning somatothermal stimulation on right seventh intercostal nerve territory increases hepatic heat shock protein 70 and protects the liver from ischemia-reperfusion injury in rats.
Reperfusion Injury
Prior heat stress improves survival of ischemic-reperfused skeletal muscle in vivo.
Reperfusion Injury
Protective effect of heat preconditioning of rat liver graft resulting in improved transplant survival.
Reperfusion Injury
Protective role of microRNA-27a upregulation and HSP90 silencing against cerebral ischemia-reperfusion injury in rats by activating PI3K/AKT/mTOR signaling pathway.
Reperfusion Injury
Reduction of skeletal muscle injury in composite tissue allotransplantation by heat stress preconditioning.
Reperfusion Injury
Retraction notice to "Protective role of microRNA-27a upregulation and HSP90 silencing against cerebral ischemia-reperfusion injury in rats by activating PI3K/AKT/mTOR signaling pathway" [Int. Immunopharmacol. 86 (2020) 106635].
Reperfusion Injury
Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice.
Reperfusion Injury
Role of ultrasound and microbubble-mediated heat shock protein 72 siRNA on ischemia-reperfusion liver injury in rat.
Reperfusion Injury
Roles of MAPKAPK-2 and HSP27 in the reduction of renal ischemia-reperfusion injury by ischemic postconditioning in rats.
Reperfusion Injury
Salvianolate increases heat shock protein expression in a cerebral ischemia-reperfusion injury model.
Reperfusion Injury
Selective renal overexpression of human heat shock protein 27 reduces renal ischemia-reperfusion injury in mice.
Reperfusion Injury
Sequence of reperfusion influences ischemia/reperfusion injury and primary graft function following porcine liver transplantation.
Reperfusion Injury
Sevoflurane relieves hepatic ischemia-reperfusion injury by inhibiting the expression of Grp78.
Reperfusion Injury
Sex differences in heat shock protein 72 expression and localization in rats following renal ischemia-reperfusion injury.
Reperfusion Injury
The augmentative effect of repeated heat shock preconditioning on the production of heat shock protein 72 and on ischemic tolerance in rat liver tissue.
Reperfusion Injury
The mechanistic studies of acupuncture and moxibustion in Taiwan.
Reperfusion Injury
The protective effects of heat shock protein 22 in lung ischemia-reperfusion injury mice.
Reperfusion Injury
The role of heat shock protein 90 in modulating ischemia-reperfusion injury in the kidney.
Reperfusion Injury
The role of microRNA in modulating myocardial ischemia-reperfusion injury.
Reperfusion Injury
Time course of tolerance to ischemia-reperfusion injury and induction of heat shock protein 72 by heat stress in the rat heart.
Reperfusion Injury
Vitamin D3 and erythropoietin protect against renal ischemia-reperfusion injury via heat shock protein 70 and microRNA-21 expression.
Reperfusion Injury
[Effects of Electroacupuncture and Moxibustion Pretreatment on Expressions of HSP 27, HSP 70, HSP 90 at Different Time-points in Rabbits with Myocardial Ischemia-reperfusion Injury].
Reperfusion Injury
[In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat]
Reperfusion Injury
[Mild hypothermia combined with hydrogen sulfide alleviates hippocampal endoplasmic reticulum stress after global cerebral ischemia-reperfusion].
Reperfusion Injury
[Progress of researches on the protective effect of acupucture in resisting myocardial ischemia-reperfusion injury]
Reperfusion Injury
[Protective effect of heat shock protein 70 and magnesium sulfate supplementation on renal ischemia reperfusion injury].
Reperfusion Injury
[Role of endoplasmic reticulum stress-related molecule GRP78 in global cerebral ischemia-reperfusion injury aggravated by hypertension in rats].
Reperfusion Injury
[The protective effect of heat shock protein 72 by Doxorubicin in cold ischemia-reperfusion injury of the rat liver]
Reproductive Tract Infections
Humoral immune response to conserved epitopes of Chlamydia trachomatis and human 60-kDa heat-shock protein in women with pelvic inflammatory disease.
Reproductive Tract Infections
Immune Recognition of the 60kD Heat Shock Protein: Implications for Subsequent Fertility.
Reproductive Tract Infections
Immunity to heat shock proteins and pregnancy outcome.
Respiratory Distress Syndrome
A cytosolic heat shock protein 90 and co-chaperone p23 complex activates RIPK3/MLKL during necroptosis of endothelial cells in acute respiratory distress syndrome.
Respiratory Distress Syndrome
Alveolar macrophages of patients with adult respiratory distress syndrome express high levels of heat shock protein 72 mRNA.
Respiratory Distress Syndrome
Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attention.
Respiratory Distress Syndrome
Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome.
Respiratory Distress Syndrome
Enhanced heat shock protein 70 expression alters proteasomal degradation of IkappaB kinase in experimental acute respiratory distress syndrome.
Respiratory Distress Syndrome
Heat shock protein 70 and the acute respiratory distress syndrome.
Respiratory Distress Syndrome
Inducibility of the 70 kD heat shock protein in peripheral blood monocytes is decreased in human acute respiratory distress syndrome and recovers over time.
Respiratory Distress Syndrome
Molecular-biological analysis of acute lung injury (ALI) induced by heat exposure and/or intravenous administration of oleic acid.
Retinal Degeneration
A role of Heat Shock Protein 70 in Photoreceptor Cell Death: Potential as a Novel Therapeutic Target in Retinal Degeneration.
Retinal Degeneration
Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration.
Retinal Degeneration
Clinical and functional analyses of AIPL1 variants reveal mechanisms of pathogenicity linked to different forms of retinal degeneration.
Retinal Degeneration
Correction to: Human embryonic stem cell-derived extracellular vesicles alleviate retinal degeneration by upregulating Oct4 to promote retinal Müller cell retrodifferentiation via HSP90.
Retinal Degeneration
Effect of the absence of heat shock protein 70.1 (hsp70.1) on retinal photoreceptors in normal and rd mice.
Retinal Degeneration
Expression of the Endoplasmic Reticulum Stress Marker GRP78 in the Normal Retina and Retinal Degeneration Induced by Blue LED Stimuli in Mice.
Retinal Degeneration
Hsp90 as a Potential Therapeutic Target in Retinal Disease.
Retinal Degeneration
Hsp90 inhibition protects against inherited retinal degeneration.
Retinal Degeneration
Human embryonic stem cell-derived extracellular vesicles alleviate retinal degeneration by upregulating Oct4 to promote retinal Müller cell retrodifferentiation via HSP90.
Retinal Degeneration
Protective effect of sulforaphane against retinal degeneration in the Pde6(rd10) mouse model of retinitis pigmentosa.
Retinal Degeneration
Quantitative proteomics of a presymptomatic A53T alpha-synuclein Drosophila model of Parkinson disease.
Retinal Degeneration
Small heat shock protein ?A-crystallin prevents photoreceptor degeneration in experimental autoimmune uveitis.
Retinal Degeneration
Suppression of HSP27 Restores Retinal Function and Protects Photoreceptors From Apoptosis in a Light-Induced Retinal Degeneration Animal Model.
Retinal Degeneration
Suppression of Light-Induced Retinal Degeneration by Quercetin via the AP-1 Pathway in Rats.
Retinal Degeneration
The effect of oxygen on retinal degeneration in wild-type and hsp70.1 knockout neonatal retinal degeneration mice.
Retinal Degeneration
The Molecular Chaperone GRP78/BiP as a Therapeutic Target for Neurodegenerative Disorders: A Mini Review.
Retinal Degeneration
The molecular chaperone Hsp90? deficiency causes retinal degeneration by disrupting Golgi organization and vesicle transportation in photoreceptors.
Retinal Degeneration
Unfolded protein response in a Drosophila model for retinal degeneration.
Retinal Detachment
Expression of two endoplasmic reticulum stress markers, GRP78 and GADD153, in rat retinal detachment model and its implication.
Retinal Detachment
Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase.
Retinal Detachment
Significant upregulation of small heat shock protein ?A-crystallin in retinal detachment.
Retinal Diseases
Heat shock cognate-70 gene expression declines during normal aging of the primate retina.
Retinal Diseases
Hsp90 as a Potential Therapeutic Target in Retinal Disease.
Retinal Neovascularization
Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry.
Retinal Neovascularization
Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1? destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors.
Retinal Perforations
Elevated Activating Transcription Factor 4 and Glucose-Regulated 78 Kda Protein Levels Correlate with Inflammatory Cytokines in the Aqueous Humor and Vitreous of Proliferative Diabetic Retinopathy.
Retinitis
[A potential of novel therapeutic approach by heat shock protein 70 expression in retinitis pigmentosa].
Retinitis Pigmentosa
AAV delivery of GRP78/BiP promotes adaptation of human RPE cell to ER stress.
Retinitis Pigmentosa
Autophagy in Xenopus laevis rod photoreceptors is independently regulated by phototransduction and misfolded RHOP23H.
Retinitis Pigmentosa
Hsp90 as a Potential Therapeutic Target in Retinal Disease.
Retinitis Pigmentosa
Hsp90 inhibition protects against inherited retinal degeneration.
Retinitis Pigmentosa
Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90).
Retinitis Pigmentosa
Unfolded protein response in a Drosophila model for retinal degeneration.
Retinitis Pigmentosa
[Role of Heat Shock Protein 70 in Retinitis Pigmentosa and a Novel Strategy for Treatment].
Retinoblastoma
70-kDa heat shock cognate protein interacts directly with the N-terminal region of the retinoblastoma gene product pRb. Identification of a novel region of pRb-mediating protein interaction.
Retinoblastoma
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock.
Retinoblastoma
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.
Retinoblastoma
Analysis of peripheral blood mononuclear cells gene expression in endurance horses by cDNA-AFLP technique.
Retinoblastoma
Behçet's disease and antibody titers to various heat-shock protein 60s.
Retinoblastoma
Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1.
Retinoblastoma
Depsipeptide (FK228) preferentially induces apoptosis in BCR/ABL-expressing cell lines and cells from patients with chronic myelogenous leukemia in blast crisis.
Retinoblastoma
Effect of 8-bromo-cyclic AMP on neuron specific enolase, heat shock protein, nitric oxide, nitric oxide synthase and nitric oxide synthase mRNA in human retinoblastoma HXO-Rb44 cells and cell differentiation.
Retinoblastoma
Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome.
Retinoblastoma
Expression of heat shock protein 27 and alpha-crystallins in human retinoblastoma after chemoreduction.
Retinoblastoma
Expression of heat shock protein 27 and proliferating cell nuclear antigen in human retinoblastoma.
Retinoblastoma
Heat shock protein 27 promotes cell cycle progression by down-regulating E2F transcription factor 4 and retinoblastoma family protein p130.
Retinoblastoma
Human T cell leukemia virus type 1 Tax associates with a molecular chaperone complex containing hTid-1 and Hsp70.
Retinoblastoma
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Retinoblastoma
Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
Retinoblastoma
JC virus T'135, T'136 and T'165 proteins interact with cellular p107 and p130 in vivo and influence viral transformation potential.
Retinoblastoma
Liver dual arterial blood supply maintains liver regeneration: Analysis of signaling pathways in rats.
Retinoblastoma
Nuclear export of proteins and drug resistance in cancer.
Retinoblastoma
Protein interaction of retinoblastoma gene product pRb110 with M(r) 73,000 heat shock cognate protein.
Retinoblastoma
Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34-positive compartment.
Retinoblastoma
Sulfoxythiocarbamate S-4 inhibits HSP90 in human cutaneous squamous cell carcinoma cells.
Retinoblastoma
Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets.
Retinoblastoma
The Epstein-Barr virus nuclear antigen leader protein associates with hsp72/hsc73.
Retinoblastoma
The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.
Retinoblastoma
The role of ferroptosis in digestive system cancer.
Retinoblastoma
Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases.
Rhabdomyosarcoma
Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.
Rhabdomyosarcoma
Effect of inhibition of the Ubiquitin-Proteasome System and Hsp90 on growth and survival of Rhabdomyosarcoma cells in vitro.
Rhabdomyosarcoma
Elevated levels of ribosomal proteins eL36 and eL42 control expression of Hsp90 in rhabdomyosarcoma.
Rhabdomyosarcoma
Heat Shock protein 90: Role in Enterovirus 71 Entry and Assembly and Potential Target for Therapy.
Rhabdomyosarcoma
High anti tumor activity against rhabdomyosarcoma cells and low normal cells cytotoxicity of heat shock protein 90 inhibitors, with special emphasis on 17-[2-(pyrrolidin-1-yl)ethyl]-aminno-17-demethoxygeldanamycin.
Rhabdomyosarcoma
HSP90 antagonist, geldanamycin, inhibits proliferation, induces apoptosis and blocks migration of rhabdomyosarcoma cells in vitro and seeding into bone marrow in vivo.
Rhabdomyosarcoma
Non-Thermal Plasma Application in Tumor-Bearing Mice Induces Increase of Serum HMGB1.
Rhabdomyosarcoma, Alveolar
17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma.
Rheumatic Diseases
Detection of autoantibodies to the 90 kDa heat shock protein in systemic lupus erythematosus and other autoimmune diseases.
Rheumatic Diseases
In the Search of Potential Serodiagnostic Proteins to Discriminate Between Acute and Chronic Q Fever in Humans. Some Promising Outcomes.
Rheumatic Diseases
Levels of antibodies against human heat shock protein (HSP) 60 in patients with glaucoma in Poland.
Rheumatic Fever
Expression of heat-shock proteins in Streptococcus pyogenes and their immunoreactivity with sera from patients with streptococcal diseases.
Rheumatic Heart Disease
Decreased Cardiac Expression of Heat Shock Protein 27 is Associated with Atrial Fibrillation in Patients with Rheumatic Heart Disease.
Rhinitis
miR?495 enhances the efficacy of radiotherapy by targeting GRP78 to regulate EMT in nasopharyngeal carcinoma cells.
Rhinitis, Allergic
Correlations Between the Adenotonsillar Microbiome and Clinical Characteristics of Pediatric Patients With Snoring.
Rhinitis, Allergic
Disruption of Heat Shock Protein 90 (Hsp90)-Protein Kinase C? (PKC?) Interaction by (-)-Maackiain Suppresses Histamine H1 Receptor Gene Transcription in HeLa Cells.
Rhinitis, Allergic
Expression of HSP70 in peripheral lymphocytes of the patients with allergic rhinitis.
Rhinitis, Allergic
Expression of substance P, vasoactive intestinal peptide and heat shock protein 70 in nasal mucosal smears of patients with allergic rhinitis: investigation using a liquid-based method.
Rhinitis, Allergic
T-helper 2 cytokine-induced heat shock protein 70 secretion and its potential association with allergic rhinitis.
Rhinitis, Allergic, Seasonal
Expression of substance P, vasoactive intestinal peptide and heat shock protein 70 in nasal mucosal smears of patients with allergic rhinitis: investigation using a liquid-based method.
Rift Valley Fever
Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.
Rosacea
Hypothesis of demodicidosis rosacea flushing etiopathogenesis.
Rotavirus Infections
Amino acid domains 280-297 of VP6 and 531-554 of VP4 are implicated in heat shock cognate protein hsc70-mediated rotavirus infection.
Rotavirus Infections
Rotavirus receptor proteins Hsc70 and integrin ?v?3 are located in the lipid microdomains of animal intestinal cells.
Rotavirus Infections
The molecular chaperone heat shock protein-90 positively regulates rotavirus infectionx.
Rotavirus Infections
The tight junction protein JAM-A functions as coreceptor for rotavirus entry into MA104 cells.
Rubella
Heat Shock Protein 90 Ensures the Integrity of Rubella virus p150 Protein and Supports Viral Replication.
Salmonella Infections
Co-expression of S. Typhi GroEL and IL-22 gene augments immune responses against Salmonella infection.
Salmonella Infections
Hsc70 is a Component of Bacterially Generated Actin-Rich Structures: An Immunolocalization Study.
Salpingitis
Cell-mediated immune response to the recombinant 57-kDa heat-shock protein of Chlamydia trachomatis in women with salpingitis.
Salpingitis
Humoral immune response to the chlamydial heat shock proteins hsp60 and hsp70 in Chlamydia-associated chronic salpingitis with tubal occlusion.
Salpingitis
Serological responses of patients with ectopic pregnancy to epitopes of the Chlamydia trachomatis 60 kDa heat shock protein.
Sarcoidosis
A quantitative proteomic analysis of soluble bronchoalveolar fluid proteins from patients with sarcoidosis and chronic beryllium disease.
Sarcoidosis
Association between heat shock protein 70/Hom genetic polymorphisms and uveitis in patients with sarcoidosis.
Sarcoidosis
Genetic influences on sarcoidosis.
Sarcoidosis
[Detection and identification of mycobacterial gene in skin lesions and lymph nodes in patients with sarcoidosis]
Sarcoma
17-AAG mediated targeting of Hsp90 limits tert activity in peritoneal sarcoma related malignant ascites by downregulating cyclin D1 during cell cycle entry.
Sarcoma
A phase 1 study of the heat shock protein 90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft tissue sarcomas.
Sarcoma
CD3- large granular lymphocytes recognize a heat-inducible immunogenic determinant associated with the 72-kD heat shock protein on human sarcoma cells.
Sarcoma
Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells.
Sarcoma
Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90, and hsp70.
Sarcoma
Conjunctival Melanoma: Genetic and Epigenetic Insights of a Distinct Type of Melanoma.
Sarcoma
Distinct profiles of oxidative stress-related and matrix proteins in adult bone and soft tissue osteosarcoma and desmoid tumors: A proteomics study.
Sarcoma
Elevated expression of HSP90 and the antitumor effect of an HSP90 inhibitor via inactivation of the Akt/mTOR pathway in undifferentiated pleomorphic sarcoma.
Sarcoma
Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma.
Sarcoma
Expression and its clinical significance of heat shock protein gp96 in human osteosarcoma.
Sarcoma
Expression of gene-specific RNA in cultured cells exposed to rotating 60-Hz magnetic fields.
Sarcoma
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours.
Sarcoma
Heat shock protein 70-associated peptides elicit specific cancer immunity.
Sarcoma
Heat shock protein 90 inhibitors in non-small-cell lung cancer.
Sarcoma
Heat shock protein antibodies in sarcoma patients undergoing 41.8 degrees C whole body hyperthermia.
Sarcoma
HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas.
Sarcoma
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.
Sarcoma
Immunization with heat shock protein 70 from methylcholanthrene-induced sarcomas induces tumor protection correlating with in vitro T cell responses.
Sarcoma
Liver dual arterial blood supply maintains liver regeneration: Analysis of signaling pathways in rats.
Sarcoma
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.
Sarcoma
Prophylactic Antitumor Effect of Mixed Heat Shock Proteins/Peptides in Mouse Sarcoma.
Sarcoma
Protein kinase C delta-mediated cytoskeleton remodeling is involved in aloe-emodin-induced photokilling of human lung cancer cells.
Sarcoma
STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma.
Sarcoma
Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprinting.
Sarcoma
Targeted agents for sarcoma: is individualized therapy possible in such a diverse tumor type?
Sarcoma
Targets for cancer therapy in childhood sarcomas.
Sarcoma, Avian
A 50-kDa cytosolic protein complexed with the 90-kDa heat shock protein (hsp90) is the same protein complexed with pp60v-src hsp90 in cells transformed by the Rous sarcoma virus.
Sarcoma, Avian
Biosynthesis of a novel transformation-sensitive heat-shock protein that binds to collagen. Regulation by mRNA levels and in vitro synthesis of a functional precursor.
Sarcoma, Avian
Evaluation of viral and mammalian promoters for driving transgene expression in mouse liver.
Sarcoma, Avian
Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system.
Sarcoma, Ewing
A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study.
Sarcoma, Ewing
Cooperative treatment effectiveness of ATR and HSP90 inhibition in Ewing's sarcoma cells.
Sarcoma, Ewing
Heat shock protein 72 (HSP72), a hyperthermia-inducible immunogenic determinant on leukemic K562 and Ewing's sarcoma cells.
Sarcoma, Ewing
Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma.
Sarcoma, Ewing
Proteomic identification of heat shock protein 27 as a differentiation and prognostic marker in neuroblastoma but not in Ewing's sarcoma.
Sarcoma, Kaposi
Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins.
Sarcoma, Synovial
Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models.
Sarcoma, Synovial
Synergism of heat shock protein 90 and histone deacetylase inhibitors in synovial sarcoma.
Sarcopenia
Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people.
Sarcopenia
Sixteen weeks of resistance training decrease plasma heat shock protein 72 (eHSP72) and increase muscle mass without affecting high sensitivity inflammatory markers' levels in sarcopenic men.
Schistosomiasis
Elevated serum antibody against Schistosoma japonicum HSP60 as a promising biomarker for liver pathology in schistosomiasis.
Schistosomiasis
Expression of heat shock protein 47, transforming growth factor-beta 1, and connective tissue growth factor in liver tissue of patients with Schistosoma japonicum-induced hepatic fibrosis.
Schistosomiasis
Fine specificity of autoantibodies to calreticulin: epitope mapping and characterization.
Schistosomiasis japonica
Identification of the resistance of a novel molecule heat shock protein 90alpha (HSP90alpha) in Microtus fortis to Schistosoma japonicum infection.
Schistosomiasis japonica
[Roles of transforming growth factor - ?1 and heat shock protein 47 in progression of Schistosoma japonicum-induced hepatic fibrosis].
Schistosomiasis mansoni
The humoral response to heat shock protein 70 in human and murine Schistosomiasis mansoni.
Scleroderma, Systemic
Antibodies to mycobacterial 65 kDa heat shock protein in systemic sclerosis (scleroderma).
Scleroderma, Systemic
Autoantibodies to a collagen-specific molecular chaperone, heat-shock protein 47, in systemic sclerosis.
Scleroderma, Systemic
Heat shock protein 90 inhibition: A potential double- or triple-edged sword in the treatment of mucous membrane pemphigoid.
Scleroderma, Systemic
Inhibition of Hsp90 Counteracts the Established Experimental Dermal Fibrosis Induced by Bleomycin.
Scleroderma, Systemic
Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study.
Scleroderma, Systemic
Serum heat shock protein 27 levels in patients with systemic sclerosis: a possible biomarker of skin sclerosis.
Scleroderma, Systemic
Serum levels of heat shock protein 70, a biomarker of cellular stress, are elevated in patients with systemic sclerosis: association with fibrosis and vascular damage.
Scrapie
Changes in HSP gene and protein expression in natural scrapie with brain damage.
Scrapie
Differential molecular chaperone response associated with various mouse adapted scrapie strains.
Scrapie
Increased expression of heat shock protein, transferrin, and beta 2-microglobulin in astrocytes during scrapie.
Scrapie
Infection by ME7 prion is not modified in transgenic mice expressing the yeast chaperone Hsp104 in neurons.
Scrapie
Overexpression of PLK3 Mediates the Degradation of Abnormal Prion Proteins Dependent on Chaperone-Mediated Autophagy.
Scrapie
Polymorphisms in the HSP90AA1 5' flanking region are associated with scrapie incubation period in sheep.
Scrub Typhus
A highly sensitive quantitative real-time PCR assay based on the groEL gene of contemporary Thai strains of Orientia tsutsugamushi.
Scrub Typhus
Laboratory diagnosis and genotype identification of scrub typhus from Pinggu district, Beijing, 2008 and 2010.
Scrub Typhus
Molecular epidemic survey on co-prevalence of scrub typhus and marine typhus in Yuxi city, Yunnan province of China.
Scrub Typhus
Molecular phylogenetic analysis of Orientia tsutsugamushi based on the groES and groEL genes.
Scrub Typhus
Scrub typhus in Puducherry, India: Application of nested PCR targeting three different genes - 56 kDa, 47 kDa and groEL of Orientia tsutsugamushi and comparison with ST IgM ELISA.
Scrub Typhus
Single-nucleotide polymorphisms in Toll-like receptor (TLR)-2, TLR4 and heat shock protein 70 genes and susceptibility to scrub typhus.
Scrub Typhus
Use of Multiplex Real-Time PCR to Diagnose Scrub Typhus.
Seizures
Behavioral changes and expression of heat shock protein hsp-70 mRNA, brain-derived neurotrophic factor mRNA, and cyclooxygenase-2 mRNA in rat brain following seizures induced by systemic administration of kainic acid.
Seizures
Bilateral intranigral NMDA blockade increases status duration and neuronal injury from systemic kainic acid.
Seizures
Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade.
Seizures
Cognitive Function and Heat Shock Protein 70 in Children With Temporal Lobe Epilepsy.
Seizures
Correlation between electroconvulsive seizure and HSC70 mRNA induction in mice brain.
Seizures
Correlation between seizure intensity and stress protein expression after limbic epilepsy in the rat brain.
Seizures
Decrease in level of APG-2, a member of the heat shock protein 110 family, in murine brain following systemic administration of kainic acid.
Seizures
Deep prepiriform cortex modulates kainate-induced hippocampal injury.
Seizures
Effects of exogenous heat shock protein 70 and quercetin on NMDA-induced seizures.
Seizures
Effects of ferulic acid on oxidative stress, heat shock protein 70, connexin 43, and monoamines in the hippocampus of pentylenetetrazole-kindled rats.
Seizures
Effects of manganese complexes of curcumin and diacetylcurcumin on kainic acid-induced neurotoxic responses in the rat hippocampus.
Seizures
Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat.
Seizures
Epilepsy: HSP90 inhibition suppresses seizures.
Seizures
Exogenous protein Hsp70/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures.
Seizures
Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy.
Seizures
Gradation of kainic acid-induced rat limbic seizures and expression of hippocampal heat shock protein-70.
Seizures
Heat shock protein 27 rescues motor neurons following nerve injury and preserves muscle function.
Seizures
High induction threshold for transcription factor KROX-20 in the rat brain: partial co-expression with heat shock protein 70 following limbic seizures.
Seizures
Hippocampal expression of heat shock proteins in mesial temporal lobe epilepsy with psychiatric comorbidities and their relation to seizure outcome.
Seizures
Hsp60 response in experimental and human temporal lobe epilepsy.
Seizures
Hyperthermic induction of the 27-kDa heat shock protein (Hsp27) in neuroglia and neurons of the rat central nervous system.
Seizures
Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury.
Seizures
Induction by synaptic zinc of heat shock protein-70 in hippocampus after kainate seizures.
Seizures
Induction of constitutive heat shock protein 73 mRNA in the dentate gyrus by seizures.
Seizures
Induction of glucose regulated protein (grp78) and inducible heat shock protein (hsp70) mRNAs in rat brain after kainic acid seizures and focal ischemia.
Seizures
Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children.
Seizures
MR imaging and 1H-MR spectroscopy in a case of juvenile Alexander disease.
Seizures
Neurofilament heavy chain and heat shock protein 70 as markers of seizure-related brain injury.
Seizures
Overexpression of 14-3-3? Increases Brain Levels of C/EBP Homologous Protein CHOP.
Seizures
Overexpression of rat heat shock protein 70 reduces neuronal injury after transient focal ischemia, transient global ischemia, or kainic acid-induced seizures.
Seizures
Protective effect of vineatrol against kainic acid induced seizures, oxidative stress and on the expression of heat shock proteins in rats.
Seizures
Responses of heat shock proteins hsp27, alphaB-crystallin, and hsp70 in rat brain after kainic acid-induced seizure activity.
Seizures
Silymarin Inhibits Glutamate Release and Prevents against Kainic Acid-Induced Excitotoxic Injury in Rats.
Seizures
Strain-dependent effects of sub-chronically infused losartan against kainic acid-induced seizures, oxidative stress, and heat shock protein 72 expression.
Seizures
The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death.
Seizures
The pattern of neuronal injury following seizures induced by intranigral kainic acid.
Seizures
Truncating biallelic variant in DNAJA1, encoding the co-chaperone Hsp40, is associated with intellectual disability and seizures.
Seizures
[EFfect of quercetin on the severity of chemically induced seizures and the content of heat shock protein 70 in the rat brain structures]
Seizures
[Effects of W-7 on the expression of GRP78 and neuronal apoptosis in immature rat hippocampus after status convulsion].
Seizures
[The microglial activation and the expression of heat shock protein 27 through the propagation pathway of kainic acid-induced hippocampal seizure in the rat]
Seizures, Febrile
Expression of Hsp72 in lymphocytes in patients with febrile convulsion.
Sepsis
A Case of Bloodstream Infection of Bacteroides pyogenes Identified by 16S rRNA, gyrB, and hsp60 Gene Sequencing.
Sepsis
An in vitro model to consider the effect of 2 mM glutamine and KNK437 on endotoxin-stimulated release of heat shock protein 70 and inflammatory mediators.
Sepsis
Analysis of two human leukocyte antigen-linked polymorphic heat shock protein 70 genes in patients with severe sepsis.
Sepsis
Association between heat shock protein 70 gene polymorphisms and clinical outcomes in intensive care unit patients with sepsis.
Sepsis
Attenuation of mitochondrial unfolded protein response is associated with hepatic dysfunction in septic rats.
Sepsis
Caffeic acid phenethyl ester reduces mortality and sepsis-induced lung injury in rats*
Sepsis
Caffeic acid phenethyl ester reduces mortality and sepsis-induced lung injury in rats.
Sepsis
Cd40 but not CD154 knockout mice have reduced inflammatory response in polymicrobial sepsis: a potential role for Escherichia coli heat shock protein 70 in CD40-mediated inflammation in vivo.
Sepsis
Chronic acid water feeding protects mice against lethal gut-derived sepsis due to Pseudomonas aeruginosa.
Sepsis
Core temperature correlates with expression of selected stress and immunomodulatory genes in febrile patients with sepsis and noninfectious SIRS.
Sepsis
Curcumin suppresses inflammatory cytokines and heat shock protein 70 release and improves metabolic parameters during experimental sepsis.
Sepsis
Cytochrome c oxidase as the target of the heat shock protective effect in septic liver.
Sepsis
Damage-associated molecular patterns and immune activation in bipolar disorder.
Sepsis
Dehydroepiandrosterone: a modulator of cellular immunity and heat shock protein 70 production during polymicrobial sepsis.
Sepsis
Differential induction of brain heme oxygenase-1 and heat shock protein 70 mRNA in sepsis.
Sepsis
Early propranolol treatment induces lung heme-oxygenase-1, attenuates metabolic dysfunction, and improves survival following experimental sepsis.
Sepsis
Endotoxin inhibits heat shock protein 70 (HSP70) expression in peripheral blood mononuclear cells of patients with severe sepsis.
Sepsis
Enhanced expression of heat shock proteins in activated polymorphonuclear leukocytes in patients with sepsis.
Sepsis
Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
Sepsis
Exogenous heat shock protein 70 mediates sepsis manifestations and decreases the mortality rate in rats.
Sepsis
Expression of heat shock protein 70 in leukocytes of patients with sepsis.
Sepsis
Extracellular heat shock protein 60 (Hsp60) levels in children with septic shock.
Sepsis
Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy.
Sepsis
Glutamine attenuates lung injury and improves survival after sepsis: role of enhanced heat shock protein expression.
Sepsis
Glutamine reduces myocardial cell apoptosis in a rat model of sepsis by promoting expression of heat shock protein 90.
Sepsis
Glutamine suppresses Hsp72 not Hsp90? and is not inducing Th1, Th2, or Th17 cytokine responses in human septic PBMCs.
Sepsis
Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression.
Sepsis
GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation.
Sepsis
Heat shock pretreatment prevents cardiac mitochondrial dysfunction during sepsis.
Sepsis
Heat shock protein 60 as a biomarker for acute kidney injury secondary to septic shock in pediatric patients, Egyptian multicenter experience.
Sepsis
Heat shock protein 72 expressing stress in sepsis: unbridgeable gap between animal and human studies--a hypothetical "comparative" study.
Sepsis
Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.
Sepsis
Heat shock response reduces intestinal permeability in septic mice: potential role of interleukin-10.
Sepsis
Heat-shock protein-90 prolongs septic neutrophil survival by protecting c-Src kinase and caspase-8 from proteasomal degradation.
Sepsis
HSP-Target of Therapeutic Agents in Sepsis Treatment.
Sepsis
Identification of meningococcal LPS as a major monocyte activator in IL-10 depleted shock plasmas and CSF by blocking the CD14-TLR4 receptor complex.
Sepsis
Impaired inducibility of heat shock protein 70 in peripheral blood lymphocytes of patients with severe sepsis.
Sepsis
Increased extracellular heat shock protein 90? in severe sepsis and SIRS associated with multiple organ failure and related to acute inflammatory-metabolic stress response in children.
Sepsis
Increased grp78 transcription is correlated to reduced tlr4 transcription in patients surviving sepsis.
Sepsis
Lipopolysaccharide up-regulates heat shock protein expression in rat lung pericytes.
Sepsis
Mechanisms of Thrombocytopenia During Septic Shock: A Multiplex Cluster Analysis of Endogenous Sepsis Mediators.
Sepsis
Mitochondrial membrane potential and apoptosis peripheral blood monocytes in severe human sepsis.
Sepsis
Pediatric Sepsis - Part V: Extracellular Heat Shock Proteins: Alarmins for the Host Immune System.
Sepsis
Protection against pneumococcal infection elicited by immunization with multiple pneumococcal heat shock proteins.
Sepsis
Radicicol, a Hsp90 inhibitor, inhibits intestinal inflammation and leakage in abdominal sepsis.
Sepsis
Radicicol, an Hsp90 inhibitor, inhibits intestinal inflammation and leakage in abdominal sepsis.
Sepsis
Release of endogenous heat shock protein 72 on the survival of sepsis in rats.
Sepsis
Role of sepsis in the development of limb muscle weakness in a porcine intensive care unit model.
Sepsis
Septicemia caused by tick-borne bacterial pathogen Candidatus Neoehrlichia mikurensis.
Sepsis
Similar Metabolic, Innate Immunity, and Adipokine Profiles in Adult and Pediatric Sepsis Versus Systemic Inflammatory Response Syndrome-A Pilot Study.
Sepsis
The association of innate immune response gene polymorphisms and puerperal group A streptococcal sepsis.
Sepsis
The effect of 2 mMol glutamine supplementation on HSP70 and TNF-? release by LPS stimulated blood from healthy children.
Sepsis
The Heat Shock Protein 70 Plays a Protective Role in Sepsis by Maintenance of the Endothelial Permeability.
Sepsis
The interaction between Hsp70 and TNF-alpha expression: a novel mechanism for protection of the myocardium against post-injury depression.
Sepsis
The role of heat shock protein 70 in mediating age-dependent mortality in sepsis.
Sepsis
The small heat shock protein HSPB1 protects mice from sepsis.
Sepsis
Thermal Steam Aerosolization Protects Against Lipopolysaccharide-Induced Sepsis in Rats.
Sepsis
Treatment of a critically ill child with disseminated Candida glabrata with a recombinant human antibody specific for fungal heat shock protein 90 and liposomal amphotericin B, caspofungin, and voriconazole.
Sepsis
Xuebijing Injection Maintains GRP78 Expression to Prevent Candida albicans-Induced Epithelial Death in the Kidney.
Sepsis
[Research properties of the exogenous recombinant human heat shock protein HSP70 on test rodents].
Sepsis
[The different effects of glutamine on macrophage cytokines release in vivo and in vitro]
Sertoli Cell Tumor
Testicular superoxide dismutase activity, heat shock protein 70 concentration and blood plasma inhibin-alpha concentration of dogs with a Sertoli cell tumor in a unilateral cryptorchid testis.
Severe Combined Immunodeficiency
Inhibition of tumor growth in mice with severe combined immunodeficiency is mediated by heat shock protein 70 (Hsp70)-peptide-activated, CD94 positive natural killer cells.
Sexually Transmitted Diseases
Induction of messenger RNA for the 70 kDa heat shock protein in HeLa cells and the human endocervix following exposure to semen: implications for antisperm antibody production and susceptibility to sexually transmitted infections.
Sexually Transmitted Diseases
Prevalence and correlates of antibody to chlamydial heat shock protein in women attending sexually transmitted disease clinics and women with confirmed pelvic inflammatory disease.
Shock, Septic
A toxic shock syndrome toxin-1 peptide that shows homology to amino acids 180-193 of mycobacterial heat shock protein 65 is presented as conventional antigen.
Shock, Septic
A toxic shock syndrome toxin-1 peptide that shows homology to mycobacterial heat shock protein 18 is presented as conventional antigen to T cells by multiple HLA-DR alleles.
Shock, Septic
An in vitro model to consider the effect of 2 mM glutamine and KNK437 on endotoxin-stimulated release of heat shock protein 70 and inflammatory mediators.
Shock, Septic
Exercise pretraining attenuates endotoxin-induced hemodynamic alteration in type I diabetic rats.
Shock, Septic
Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
Shock, Septic
Extracellular heat shock protein 60 (Hsp60) levels in children with septic shock.
Shock, Septic
Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy.
Shock, Septic
Genetic variation in heat shock protein 70 is associated with septic shock: narrowing the association to a specific haplotype.
Shock, Septic
Glutamine induces heat shock protein and protects against endotoxin shock in the rat.
Shock, Septic
Heat shock protein 60 as a biomarker for acute kidney injury secondary to septic shock in pediatric patients, Egyptian multicenter experience.
Shock, Septic
Heat shock protein 70-2+1267 AA homozygotes have an increased risk of septic shock in adults with community-acquired pneumonia.
Shock, Septic
Heat shock protein: tracing the enemy in septic shock.
Shock, Septic
Oral administration of geranylgeranylacetone improves survival rate in a rat endotoxin shock model: administration timing and heat shock protein 70 induction.
Sickle Cell Trait
Genetic polymorphisms associated with exertional rhabdomyolysis.
Skin Diseases
A survey and analysis of the role of molecular chaperone proteins and imidazole-containing dipeptide-based compounds as molecular escorts into the skin during stress, injury, water structuring and other types of cutaneous pathophysiology.
Skin Diseases
Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid.
Skin Diseases
Autoantibodies to human stress proteins. A survey of various rheumatic and other inflammatory diseases.
Skin Diseases
Biologic Activities of Molecular Chaperones and Pharmacologic Chaperone Imidazole-Containing Dipeptide-Based Compounds: Natural Skin Care Help and the Ultimate Challenge. Implication for Adaptive Responses in the Skin.
Skin Diseases
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Skin Diseases
Topically Applied Hsp90 Blocker 17AAG Inhibits Autoantibody-Mediated Blister-Inducing Cutaneous Inflammation.
Skin Diseases
Water-structuring technology with the molecular chaperone proteins: indicated application of the ?-crystallin domains and imidazole-containing peptidomimetics in cosmetic skin care systems or dermatological therapeutic drug carrier formulations.
Skin Diseases, Vesiculobullous
Heat shock protein 90: a pathophysiological factor and novel treatment target in autoimmune bullous skin diseases.
Skin Neoplasms
17-Aminogeldanamycin Inhibits Constitutive Nuclear Factor-Kappa B (NF-?B) Activity in Patient-Derived Melanoma Cell Lines.
Skin Neoplasms
Heat shock transcription factor-1 regulates heat shock protein-72 expression in human keratinocytes exposed to ultraviolet B light.
Skin Neoplasms
In Silico Studies on Fungal Metabolite against Skin Cancer Protein (4,5-Diarylisoxazole HSP90 Chaperone).
Sleep Apnea, Obstructive
Assessment of oxidative stress markers and hearing thresholds in patients with obstructive sleep apnea-hypopnoea treated with cysteine and superoxide dismutase therapy.
Sleep Apnea, Obstructive
Heat shock protein 72 level decreases during sleep in patients with obstructive sleep apnea syndrome.
Sleep Apnea, Obstructive
Hypoxia-sensitive molecules may modulate the development of atherosclerosis in sleep apnoea syndrome.
Sleep Deprivation
Acute sleep deprivation induces cardioprotection against ischemia/ reperfusion injury through reducing inflammatory responses: the role of central GABA-A receptors.
Sleep Deprivation
Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep.
Sleep Deprivation
Does the compromised sleep and circadian disruption of night and shiftworkers make them highly vulnerable to 2019 coronavirus disease (COVID-19)?
Sleep Deprivation
Gene expression in the brain across the sleep-waking cycle.
Sleep Deprivation
Gene expression in the rat brain during sleep deprivation and recovery sleep: an Affymetrix GeneChip(R) study.
Sleep Deprivation
Gene expression in the rat cerebral cortex: comparison of recovery sleep and hypnotic-induced sleep.
Sleep Deprivation
Geranylgeranylacetone, an inducer of HSP 70, attenuates REM sleep rebound after sleep deprivation.
Sleep Deprivation
Sleep deprivation increase the expression of inducible heat shock protein 70 in rat gastric mucosa.
Sleep Deprivation
[Study of the protective effects of exogenous heat shock protein 70 kDa in the model of sleep deprivation in pigeons Columba livia].
Small Cell Lung Carcinoma
A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer.
Small Cell Lung Carcinoma
Differential expression of heat shock protein 90 isoforms in small cell lung cancer.
Small Cell Lung Carcinoma
Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells.
Small Cell Lung Carcinoma
Heat shock protein 90 inhibition in lung cancer.
Small Cell Lung Carcinoma
HSP90 inhibitor (NVP-AUY922) enhances the anti-cancer effect of BCL-2 inhibitor (ABT-737) in small cell lung cancer expressing BCL-2.
Small Cell Lung Carcinoma
Induction of premature senescence by hsp90 inhibition in small cell lung cancer.
Small Cell Lung Carcinoma
Organ-specific efficacy of HSP90 inhibitor in multiple-organ metastasis model of chemorefractory small cell lung cancer.
Small Cell Lung Carcinoma
Serum Heat Shock Protein 70, as a Potential Biomarker for Small Cell Lung Cancer.
Small Cell Lung Carcinoma
Tumor cell expression of heat shock protein (HSP) 72 is influenced by HSP72 [HSPA1B A(1267)G] polymorphism and predicts survival in small Cell lung cancer (SCLC) patients.
Small Cell Lung Carcinoma
Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.
Spastic Paraplegia, Hereditary
A cell model to study different degrees of Hsp60 deficiency in HEK293 cells.
Spastic Paraplegia, Hereditary
An allosteric network in spastin couples multiple activities required for microtubule severing.
Spastic Paraplegia, Hereditary
Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13).
Spastic Paraplegia, Hereditary
Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60.
Spastic Paraplegia, Hereditary
MitCHAP-60 and Hereditary Spastic Paraplegia SPG-13 Arise from an Inactive hsp60 Chaperonin that Fails to Fold the ATP Synthase ?-Subunit.
Spastic Paraplegia, Hereditary
The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules.
Spastic Paraplegia, Hereditary
The Hsp60 folding machinery is crucial for manganese superoxide dismutase folding and function.
Spastic Paraplegia, Hereditary
The Hsp60-(p.V98I) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo.
Spinal Cord Injuries
Distinct Expression of c-Jun and HSP27 in Axotomized and Spared Bulbospinal Neurons After Cervical Spinal Cord Injury.
Spinal Cord Injuries
Exercise preconditioning protects against spinal cord injury in rats by upregulating neuronal and astroglial heat shock protein 72.
Spinal Cord Injuries
Expression of the stress proteins, ubiquitin, heat shock protein 72, and myofibrillar protein content after 12 weeks of leg cycling in persons with spinal cord injury.
Spinal Cord Injuries
Loss of hsp70.1 Decreases Functional Motor Recovery after Spinal Cord Injury in Mice.
Spinal Cord Injuries
Matrine promotes neural circuit remodeling to regulate motor function in a mouse model of chronic spinal cord injury.
Spinal Cord Injuries
MEK1/2 Inhibition Synergistically Enhances the Preventive Effects of Normobaric Oxygen on Spinal Cord Injury in Decompression Sickness Rats.
Spinal Cord Injuries
Nanoparticles Exacerbate Both Ubiquitin and Heat Shock Protein Expressions in Spinal Cord Injury: Neuroprotective Effects of the Proteasome Inhibitor Carfilzomib and the Antioxidant Compound H-290/51.
Spinal Cord Injuries
Neurotrophic factors influence upregulation of constitutive isoform of heme oxygenase and cellular stress response in the spinal cord following trauma. An experimental study using immunohistochemistry in the rat.
Spinal Cord Injuries
Nitration of Hsp90 induces cell death.
Spinal Cord Injuries
Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury.
Spinal Cord Injuries
Spinal cord injury induced heat shock protein expression is reduced by an antioxidant compound H-290/51. An experimental study using light and electron microscopy in the rat.
Spinal Cord Injuries
The change tendency of endoplasmic reticulum stress associated proteins in rats with spinal cord injury.
Spinal Cord Injuries
Time-dependent changes in caspase-3 activity and heat shock protein 25 after spinal cord transection in adult rats.
Spinal Cord Injuries
[Effect of tacrolimus on apoptosis and expression of heat shock protein 70 after acute spinal cord injury in rats]
Spinal Cord Ischemia
Effect of ischemic pretreatment on heat shock protein 72, neurologic outcome, and histopathologic outcome in a rabbit model of spinal cord ischemia.
Spinal Cord Ischemia
Establishment of a local cooling model against spinal cord ischemia representing prolonged induction of heat shock protein.
Spinal Cord Ischemia
Selective motor neuron death and heat shock protein induction after spinal cord ischemia in rabbits.
Spinocerebellar Ataxias
Altered expression of HSPA5, HSPA8 and PARK7 in spinocerebellar ataxia type 17 identified by 2-dimensional fluorescence difference in gel electrophoresis.
Spinocerebellar Ataxias
Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease.
Spinocerebellar Ataxias
BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.
Spinocerebellar Ataxias
HSP27 and cell death in spinocerebellar ataxia type 3.
Spinocerebellar Ataxias
Increased heat shock transcription factor 1 in the cerebellum reverses the deficiency of Purkinje cells in Alzheimer's disease.
Spinocerebellar Ataxias
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.
Spinocerebellar Ataxias
Transcriptional malfunctioning of heat shock protein gene expression in spinocerebellar ataxias.
Spinocerebellar Ataxias
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Spinocerebellar Ataxias
Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3.
Spondylarthropathies
Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies.
Spondylarthropathies
Spondyloarthropathies and bone resorption: a possible role of heat shock protein (Hsp70).
Spondylitis, Ankylosing
Anti-mutated citrullinated vimentin (anti-MCV) and anti-65kDa heat shock protein (anti-hsp65): New biomarkers in ankylosing spondylitis.
Spondylitis, Ankylosing
Cellular immune response to Klebsiella pneumoniae antigens in patients with HLA-B27+ ankylosing spondylitis.
Spondylitis, Ankylosing
Serum antibodies from patients with ankylosing spondylitis and Reiter's syndrome are reactive with HLA-B27 cells transfected with the Mycobacterium tuberculosis hsp60 gene.
Spondylitis, Ankylosing
T cell response to human HSP60 and yersinia 19 kDa in ankylosing spondylitis and rheumatoid arthritis: no evidence for a causal role of these antigens in the pathogenesis.
Spondylitis, Ankylosing
Upregulation of 78-kDa glucose-regulated protein in macrophages in peripheral joints of active ankylosing spondylitis.
Spondylitis, Ankylosing
[Relationship between heat shock protein 70-hom gene polymorphism and ankylosing spondylitis]
Spondylitis, Ankylosing
[The heat shock protein 70-2 gene +1267(A/G)polymorphism and susceptibility to ankylosing spondylitis in Chinese Han population.]
Spotted Fever Group Rickettsiosis
Molecular detection and groEL typing of Rickettsia aeschlimannii in Sardinian ticks.
Spotted Fever Group Rickettsiosis
Molecular epidemic survey on co-prevalence of scrub typhus and marine typhus in Yuxi city, Yunnan province of China.
Squamous Cell Carcinoma of Head and Neck
2-phenylethynesulfonamide inhibits growth of oral squamous cell carcinoma cells by blocking the function of heat shock protein 70.
Squamous Cell Carcinoma of Head and Neck
2D-DIGE proteomic characterization of head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
A microRNA-27a mimic sensitizes human oral squamous cell carcinoma HSC-4 cells to hyperthermia through downregulation of Hsp110 and Hsp90.
Squamous Cell Carcinoma of Head and Neck
A novel intronic circular RNA, circGNG7, inhibits head and neck squamous cell carcinoma progression by blocking the phosphorylation of heat shock protein 27 at Ser78 and Ser82.
Squamous Cell Carcinoma of Head and Neck
Antitumor effect of novel HSP90 inhibitor NVP-AUY922 against oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
BIIB021, a novel HSP90 inhibitor, sensitizes head and neck squamous cell carcinoma to radiotherapy.
Squamous Cell Carcinoma of Head and Neck
CD20+ Tumor Infiltrating B Lymphocyte in Oral Squamous Cell Carcinoma: Correlation with Clinicopathologic Characteristics and Heat Shock Protein 70 Expression.
Squamous Cell Carcinoma of Head and Neck
Decreased GRP78 protein expression is a potential prognostic marker of oral squamous cell carcinoma in Taiwan.
Squamous Cell Carcinoma of Head and Neck
Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Effect of 17-allylamino-17-demethoxygeldanamycin (17-AAG) on Akt protein expression is more effective in head and neck cancer cell lineages that retain PTEN protein expression.
Squamous Cell Carcinoma of Head and Neck
Effect of hypoxia on the expression of alphaB-crystallin in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling.
Squamous Cell Carcinoma of Head and Neck
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Squamous Cell Carcinoma of Head and Neck
Expression of Heat Shock Protein 70 in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma: An Immunohistochemical Study.
Squamous Cell Carcinoma of Head and Neck
Expression of heat shock protein70 in oral submucous fibrosis and oral squamous cell carcinoma: an immunohistochemical study.
Squamous Cell Carcinoma of Head and Neck
Expression pattern of heat shock protein 90 in patients with oral squamous cell carcinoma in northern Taiwan.
Squamous Cell Carcinoma of Head and Neck
Extracellular heat shock protein A9 is a novel interaction partner of podoplanin in oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells.
Squamous Cell Carcinoma of Head and Neck
Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation.
Squamous Cell Carcinoma of Head and Neck
Heat shock protein and p53 expression in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
HSP105 expression in oral squamous cell carcinoma: Correlation with clinicopathological features and outcomes.
Squamous Cell Carcinoma of Head and Neck
HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation.
Squamous Cell Carcinoma of Head and Neck
HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.
Squamous Cell Carcinoma of Head and Neck
Identification of potential biomarkers of head and neck squamous cell carcinoma using iTRAQ based quantitative proteomic approach.
Squamous Cell Carcinoma of Head and Neck
Low-Dose Hsp90 Inhibitor Selectively Radiosensitizes HNSCC and Pancreatic Xenografts.
Squamous Cell Carcinoma of Head and Neck
Novel C-Terminal Heat Shock Protein 90 Inhibitors (KU711 and Ku757) Are Effective in Targeting Head and Neck Squamous Cell Carcinoma Cancer Stem cells.
Squamous Cell Carcinoma of Head and Neck
Novel C-Terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents.
Squamous Cell Carcinoma of Head and Neck
Novel HSP90 Inhibitor NVP-AUY922 enhances the anti-tumor effect of temsirolimus against oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Overexpression of heat shock protein 27 (HSP-27) is associated with bad prognosis in oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Overexpression of heat shock protein 27 is associated with good prognosis in the patient with oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
P53-dependent radiosensitizing effects of Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin on human oral squamous cell carcinoma cell lines.
Squamous Cell Carcinoma of Head and Neck
Pharmacological inhibition of HSP90 and ras activity as a new strategy in the treatment of HNSCC.
Squamous Cell Carcinoma of Head and Neck
Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis.
Squamous Cell Carcinoma of Head and Neck
Potent activity of a novel dimeric heat shock protein 90 inhibitor against head and neck squamous cell carcinoma in vitro and in vivo.
Squamous Cell Carcinoma of Head and Neck
Prognostic significance of heat shock protein 27 (HSP27) in patients with oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Proteome-wide analysis of head and neck squamous cell carcinomas using laser-capture microdissection and tandem mass spectrometry.
Squamous Cell Carcinoma of Head and Neck
Synergistic effect of heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin and X-rays, but not carbon-ion beams, on lethality in human oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Targeted therapy in head and neck cancer.
Squamous Cell Carcinoma of Head and Neck
The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer.
Squamous Cell Carcinoma of Head and Neck
[Biology behavior of head and neck squamous cell cancer cells changes after knocking down heat shock protein 27].
ST Elevation Myocardial Infarction
Expression of Circulatory Dendritic Cells and Regulatory T-Cells in Patients with Different Subsets of Coronary Artery Disease.
Starvation
?III-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells.
Starvation
A proteome analysis of the tetracyanonickelate (II) responses in Klebsiella oxytoca.
Starvation
A Single Site Phosphorylation on Hsp82 Ensures Cell Survival during Starvation in Saccharomyces cerevisiae.
Starvation
A Triterpene Lactone from Callistemon citrinus Inhibits the PANC-1 Human Pancreatic Cancer Cells Viability through Suppression of Unfolded Protein Response.
Starvation
ADP-ribosylation of the 78-kDa glucose-regulated protein during nutritional stress.
Starvation
ADP-ribosylation of the molecular chaperone GRP78/BiP.
Starvation
Alcohol alters skeletal muscle heat shock protein gene expression in rats: these effects are moderated by sex, raised endogenous acetaldehyde, and starvation.
Starvation
Alteration of cell morphology and viability in a recA mutant of Streptococcus thermophilus upon induction of heat shock and nutrient starvation.
Starvation
An analogue of the DnaJ molecular chaperone whose expression is controlled by sigma s during the stationary phase and phosphate starvation in Escherichia coli.
Starvation
An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein.
Starvation
Arctigenin Suppresses Unfolded Protein Response and Sensitizes Glucose Deprivation-Mediated Cytotoxicity of Cancer Cells.
Starvation
Calreticulin--a stress protein induced in the renal epithelial cell line NBL-1 by amino acid deprivation.
Starvation
Cloning and expression pattern of heat shock protein genes from the endoparasitoid wasp, Pteromalus puparum in response to environmental stresses.
Starvation
Complementary autophagy inhibition and glucose metabolism with rattle-structured polydopamine@mesoporous silica nanoparticles for augmented low-temperature photothermal therapy and in vivo photoacoustic imaging.
Starvation
Development of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment.
Starvation
Differential expression of heat shock proteins and antioxidant enzymes in response to temperature, starvation, and parasitism in the Carob moth larvae, Ectomyelois ceratoniae (Lepidoptera: Pyralidae).
Starvation
Down-regulation of epidermal growth factor receptor-signaling pathway by binding of GRP78/BiP to the receptor under glucose-starved stress conditions.
Starvation
Ectopic expression of a cyanobacterial flavodoxin in creeping bentgrass impacts plant development and confers broad abiotic stress tolerance.
Starvation
Effectiveness of HSV-tk suicide gene therapy driven by the Grp78 stress-inducible promoter in esophagogastric junction and gastric adenocarcinomas.
Starvation
Effects of aquarium-related stressors on the zebrafish: a comparison of behavioral, physiological, and biochemical indicators.
Starvation
Enhanced hydrogen peroxide sensitivity and altered stress protein expression in iron-starved Mycobacterium smegmatis.
Starvation
Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway.
Starvation
Expression pattern of potential biomarker genes related to growth, ion regulation and stress in response to ammonia exposure, food deprivation and exercise in common carp (Cyprinus carpio).
Starvation
Glucose regulation of GRP78 gene expression.
Starvation
Growth-Regulated Hsp70 Phosphorylation Regulates Stress Responses and Prion Maintenance.
Starvation
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
Starvation
Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation.
Starvation
HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator.
Starvation
Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the alpha subunit of eukaryotic translation initiation factor 2 [corrected]
Starvation
Immunoproteomic identification of antigenic candidate Campylobacter jejuni and human peripheral nerve proteins involved in Guillain-Barré syndrome.
Starvation
Increased Macroautophagy in the Pathological Process of Intervertebral Disc Degeneration in Rats.
Starvation
Induced expression of the heat shock protein genes uspA and grpE during starvation at low temperatures and their influence on thermal resistance of Escherichia coli O157:H7.
Starvation
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Starvation
Involvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotide.
Starvation
Ischemia activates the ATF6 branch of the endoplasmic reticulum (ER) stress response.
Starvation
Knockdown of ERp44 leads to apoptosis via activation of ER stress in HeLa cells.
Starvation
Light-activated oxygen self-supplied starving therapy in near-infrared (NIR) window and adjuvant hyperthermia-induced tumor ablation with an augmented sensitivity.
Starvation
Metabolic modulation in Labeo rohita fingerlings during starvation: Hsp70 expression and oxygen consumption
Starvation
Mitochondrial nucleoids undergo remodeling in response to metabolic cues.
Starvation
Molecular analysis of a glucose-regulated gene (grp78) of Neurospora crassa.
Starvation
Molecular cloning of the heat-shock cognate 70 (Hsc70) gene from the two-spotted spider mite, Tetranychus urticae, and its expression in response to heat shock and starvation.
Starvation
Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.
Starvation
Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Starvation
Phosphorylation of GroEL, DnaK and other proteins from Thiobacillus ferrooxidans grown under different conditions.
Starvation
Phosphorylation of Heat Shock Protein 27 is Increased by Cast Immobilization and by Serum-free Starvation in Skeletal Muscles.
Starvation
Potentiation of chemotherapeutics by the Hsp90 antagonist geldanamycin requires a steady serum condition.
Starvation
Proteomic Analysis of Larval Midgut from the Silkworm (Bombyx mori).
Starvation
Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy.
Starvation
Quantitative proteomics identifies unanticipated regulators of nitrogen- and glucose starvation.
Starvation
Regulation of HSP60 mRNA expression in a human ovarian carcinoma cell line.
Starvation
Reversible ADP-ribosylation of the 78 kDa glucose-regulated protein.
Starvation
Role of RpoH, a heat shock regulator protein, in Escherichia coli carbon starvation protein synthesis and survival.
Starvation
Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.
Starvation
Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors.
Starvation
Structural insights into the Escherichia coli lysine decarboxylases and molecular determinants of interaction with the AAA+ ATPase RavA.
Starvation
Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma.
Starvation
Temporal changes in superoxide dismutase, catalase, and heat shock protein 70 gene expression, cortisol and antioxidant enzymes activity of Labeo rohita fingerlings subjected to starvation and refeeding.
Starvation
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells.
Starvation
Transcriptional activation of the glucose-regulated protein genes and their heterologous fusion genes by beta-mercaptoethanol.
Starvation
Use of the glucose starvation-inducible glucose-regulated protein 78 promoter in suicide gene therapy of murine fibrosarcoma.
Starvation
V-ATPase dysfunction suppresses polyphosphate synthesis in Saccharomyces cerevisiae.
Starvation
Zim17/Tim15 links mitochondrial iron-sulfur cluster biosynthesis to nuclear genome stability.
Starvation
[Expression analysis of 5 hsp70 genes in Tetrahymena thermophila].
Starvation
[Molecular chaperone GRP75 reprove cells from injury caused by glucose deprivation]
Status Epilepticus
Epileptogenesis-Associated Alterations of Heat Shock Protein 70 in a Rat Post-Status Epilepticus Model.
Status Epilepticus
Expression of the 27,000 mol. wt heat shock protein following kainic acid-induced status epilepticus in the rat.
Status Epilepticus
Heat shock protein 70 protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus via inhibition of nuclear factor-?B activation-induced nitric oxide synthase II expression.
Status Epilepticus
Induction of glucose-regulated protein (glucose-regulated protein 78/BiP and glucose-regulated protein 94) and heat shock protein 70 transcripts in the immature rat brain following status epilepticus.
Status Epilepticus
P2RX7-MAPK1/2-SP1 axis inhibits MTOR independent HSPB1-mediated astroglial autophagy.
Status Epilepticus
Reduction in heat shock protein 90 correlates to neuronal vulnerability in the rat piriform cortex following status epilepticus.
Status Epilepticus
Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins.
Status Epilepticus
The 27-kDa heat shock protein (HSP27) is a reliable hippocampal marker of full development of pilocarpine-induced status epilepticus.
Stomach Diseases
Heat shock protein: hard worker or bad offender for gastric diseases.
Stomach Diseases
Quantitative analysis of representative proteome components and clustering of Helicobacter pylori clinical strains.
Stomach Diseases
[The virtuoueffect of heat shock protein 70 and evil effect of nuclear factor-kappa B in patients with chronic gastric disease of PI-Wie damp-heat syndrome type]
Stomach Neoplasms
3,3'-diindolylmethane potentiates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of gastric cancer cells.
Stomach Neoplasms
A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese population.
Stomach Neoplasms
A new tumor-specific variant of GRP78 as target for antibody-based therapy.
Stomach Neoplasms
A peptide derived from phage display library exhibits anti-tumor activity by targeting GRP78 in gastric cancer multidrug resistance cells.
Stomach Neoplasms
A virulence factor of Helicobacter pylori: role of heat shock protein in mucosal inflammation after H. pylori infection.
Stomach Neoplasms
Antibody response to Helicobacter pylori CagA and heat-shock proteins in determining the risk of gastric cancer development.
Stomach Neoplasms
Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins.
Stomach Neoplasms
Association between Polymorphisms in Inflammatory Response-Related Genes and the Susceptibility, Progression and Prognosis of the Diffuse Histological Subtype of Gastric Cancer.
Stomach Neoplasms
Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer.
Stomach Neoplasms
Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Stomach Neoplasms
Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition.
Stomach Neoplasms
Cellular stress and redox activity proteins are involved in gastric carcinogenesis associated with Helicobacter pylori infection expressing high levels of thioredoxin-1.
Stomach Neoplasms
Clinical significance of heat shock protein 90? expression as a biomarker of prognosis in patients with gastric cancer.
Stomach Neoplasms
Clinical significance of heat shock proteins in gastric cancer following hyperthermia stress: Indications for hyperthermic intraperitoneal chemoperfusion therapy.
Stomach Neoplasms
Clinicopathological Significance of Heat Shock Protein (HSP) 27 Expression in Gastric Cancer: A Updated Meta-Analysis.
Stomach Neoplasms
Comparative proteomics analysis of gastric cancer stem cells.
Stomach Neoplasms
Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.
Stomach Neoplasms
Decreased expression of the carboxyl terminus of heat shock cognate 70 interacting protein in human gastric cancer and its clinical significance.
Stomach Neoplasms
Decreased functional expression of Grp78 and Grp94 inhibits proliferation and attenuates apoptosis in a human gastric cancer cell line in vitro.
Stomach Neoplasms
Diagnostic and prognostic value of plasma heat shock protein 90alpha in gastric cancer.
Stomach Neoplasms
Diagnostic, clinicopathologic, therapeutic and prognostic value of Plasma Heat Shock Protein 90 levels in patients with advanced Gastrointestinal Carcinoma.
Stomach Neoplasms
Discovery of tumor markers for gastric cancer by proteomics.
Stomach Neoplasms
Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells.
Stomach Neoplasms
Efrapeptin J, a new down-regulator of the molecular chaperone GRP78 from a marine Tolypocladium sp.
Stomach Neoplasms
Endoplasmic reticulum chaperone glucose-regulated protein 78 in gastric cancer: An emerging biomarker.
Stomach Neoplasms
Enhanced invasive and metastatic potential induced by transforming growth factor-beta1 might be correlated with glutathione-S-transferase-pi, cofilin and heat shock protein 27 in SGC-7901 gastric cancer cells.
Stomach Neoplasms
Estrogen receptor-?36-mediated rapid estrogen signaling regulates 78 kDa glucose-regulated protein expression in gastric carcinoma cells.
Stomach Neoplasms
Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p/HUR/VEGF axis and suppressing HSP90 degradation.
Stomach Neoplasms
Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer.
Stomach Neoplasms
Expression of heat shock protein (Hsp) 70 and Hsp 40 in gastric cancer.
Stomach Neoplasms
Expression of heat shock protein 90 beta in human gastric cancer tissue and SGC7901/VCR of MDR-type gastric cancer cell line.
Stomach Neoplasms
Expression of the 27-kDa heat shock protein (HSP27) in gastric carcinomas and adjacent normal, metaplastic, and dysplastic gastric mucosa, and its prognostic significance.
Stomach Neoplasms
GALNT5 uaRNA promotes gastric cancer progression through its interaction with HSP90.
Stomach Neoplasms
Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling.
Stomach Neoplasms
Gastric cancer-derived heat shock protein-gp96 peptide complex enhances dendritic cell activation.
Stomach Neoplasms
Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand.
Stomach Neoplasms
GKN2 promotes oxidative stress-induced gastric cancer cell apoptosis via the Hsc70 pathway.
Stomach Neoplasms
GRP78 positively regulates estrogen?stimulated cell growth mediated by ER??36 in gastric cancer cells.
Stomach Neoplasms
Heat shock protein 22 overexpression is associated with the progression and prognosis in gastric cancer.
Stomach Neoplasms
Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells.
Stomach Neoplasms
Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer.
Stomach Neoplasms
Heat shock protein 70 (HSP70) expression is associated with poor prognosis in intestinal type gastric cancer.
Stomach Neoplasms
Heat shock protein 70 antisense oligonucleotide inhibits cell growth and induces apoptosis in human gastric cancer cell line SGC-7901.
Stomach Neoplasms
Heat Shock Protein Association with Clinico-Pathological Characteristics of Gastric Cancer in Jordan : HSP70 is Predictive of Poor Prognosis.
Stomach Neoplasms
Heat-directed suicide gene therapy mediated by heat shock protein promoter for gastric cancer.
Stomach Neoplasms
Heat-shock protein 60 homologue of Helicobacter pylori is associated with adhesion of H. pylori to human gastric epithelial cells.
Stomach Neoplasms
Helicobacter pylori blood biomarker for gastric cancer risk in East Asia.
Stomach Neoplasms
Helicobacter pylori heat shock protein 60 antibodies are associated with gastric cancer.
Stomach Neoplasms
Helicobacter pylori promotes apoptosis, activates cyclooxygenase (COX)-2 and inhibits heat shock protein HSP70 in gastric cancer epithelial cells.
Stomach Neoplasms
High expression of heat shock protein 90 is associated with tumor aggressiveness and poor prognosis in patients with advanced gastric cancer.
Stomach Neoplasms
Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth.
Stomach Neoplasms
HSP90 inhibitor 17-DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidant-antioxidant balance.
Stomach Neoplasms
HSP90 inhibitor, AUY922, debilitates intrinsic and acquired lapatinib-resistant HER2-positive gastric cancer cells.
Stomach Neoplasms
In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines.
Stomach Neoplasms
Induction of a tumour-specific CTL response by exosomes isolated from heat-treated malignant ascites of gastric cancer patients.
Stomach Neoplasms
Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-epsilon/ERK/AP-1 signaling cascade.
Stomach Neoplasms
Inhibition of gastric tumor growth by a novel Hsp90 inhibitor.
Stomach Neoplasms
Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
Stomach Neoplasms
Inhibition of HSP90 with AUY922 Induces Synergy in HER2-Amplified Trastuzumab-Resistant Breast and Gastric Cancer.
Stomach Neoplasms
Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells.
Stomach Neoplasms
Is co-expression of USP22 and HSP90 more effective in predicting prognosis of gastric cancer?
Stomach Neoplasms
KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78.
Stomach Neoplasms
Leptin and fasting regulate rat gastric glucose-regulated protein 58.
Stomach Neoplasms
Mechanism study of peptide GMBP1 and its receptor GRP78 in modulating gastric cancer MDR by iTRAQ-based proteomic analysis.
Stomach Neoplasms
Mortalin is a prognostic factor of gastric cancer with normal p53 function.
Stomach Neoplasms
Neocurromycin A, a new GRP78 downregulator from Streptomyces sp. RAI364.
Stomach Neoplasms
NLRP6 suppresses gastric cancer growth via GRP78 ubiquitination.
Stomach Neoplasms
Novel targeted nuclear imaging agent for gastric cancer diagnosis: glucose-regulated protein 78 binding peptide-guided 111In-labeled polymeric micelles.
Stomach Neoplasms
Nuclear heat shock protein 110 expression is associated with poor prognosis and chemotherapy resistance in gastric cancer.
Stomach Neoplasms
Nuclear heat shock protein 110 expression is associated with poor prognosis and hyperthermo-chemotherapy resistance in gastric cancer patients with peritoneal metastasis.
Stomach Neoplasms
Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors.
Stomach Neoplasms
Overexpression of the heat shock protein HSP70 family and p53 protein and prognosis for patients with gastric cancer.
Stomach Neoplasms
Plasminogen kringle 5 suppresses gastric cancer via regulating HIF-1? and GRP78.
Stomach Neoplasms
Polymorphisms in TNF and HSP-70 show a significant association with gastric cancer and duodenal ulcer.
Stomach Neoplasms
Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers.
Stomach Neoplasms
Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells.
Stomach Neoplasms
Protective role of genetic polymorphism of heat shock protein 70-2 for gastric cancer risk.
Stomach Neoplasms
Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer.
Stomach Neoplasms
RNA interference-mediated silencing of the Hsp70 gene inhibits human gastric cancer cell growth and induces apoptosis in vitro and in vivo.
Stomach Neoplasms
Salidroside inhibits the proliferation and migration of gastric cancer cells via suppression of Src?associated signaling pathway activation and heat shock protein 70 expression.
Stomach Neoplasms
Significance of expression of heat shock protein90alpha in human gastric cancer.
Stomach Neoplasms
Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.
Stomach Neoplasms
Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer.
Stomach Neoplasms
The Clinical Value of HSP60 in Digestive System Cancers: a Systematic Review and Meta-Analysis.
Stomach Neoplasms
The cytomegalovirus protein UL138 induces apoptosis of gastric cancer cells by binding to heat shock protein 70.
Stomach Neoplasms
The meta and bioinformatics analysis of GRP78 expression in gastric cancer.
Stomach Neoplasms
The proteomics approach to find biomarkers in gastric cancer.
Stomach Neoplasms
The tumor promoting roles of HSP60 and HIF2? in gastric cancer cells.
Stomach Neoplasms
Verteporfin blocks Clusterin which is required for survival of gastric cancer stem cell by modulating HSP90 function.
Stomach Neoplasms
[Effects of HSP90 inhibitor 17-AAG on cell cycle and apoptosis of human gastric cancer cell lines SGC-7901].
Stomach Neoplasms
[Preparation of chaperone-antigen peptide vaccine derived from human gastric cancer stem cells and its immune function].
Stomach Neoplasms
[Triptolide reverses apatinib resistance in gastric cancer cell line MKN45 via inhibition of heat shock protein 70].
Stomach Ulcer
Combined application of geranylgeranylacetone and amelogenin promotes angiogenesis and wound healing in human periodontal ligament cells.
Stomach Ulcer
Endoplasmic reticulum stress response is involved in the pathogenesis of stress induced gastric lesions in rats.
Stomach Ulcer
Heat Shock Protein A4 Controls Cell Migration and Gastric Ulcer Healing.
Stomach Ulcer
Impaired gastric ulcer healing in diabetic rats: role of heat shock protein, growth factors, prostaglandins and proinflammatory cytokines.
Stomach Ulcer
Overexpression of heat shock protein 70 in stomach of stress-induced gastric ulcer-resistant rats.
Stomach Ulcer
Role of heat shock proteins in gastric inflammation and ulcer healing.
Stomach Ulcer
Russelioside B; A pregnane glycoside for treatment of gastric ulcer via modulation of heat shock protein-70 and vascular endothelial growth factor.
Stomach Ulcer
Stimulation of gastric ulcer healing by heat shock protein 70.
Stomatitis, Aphthous
Behçet's disease and antibody titers to various heat-shock protein 60s.
Stomatitis, Aphthous
Defining a T-cell epitope within HSP 65 in recurrent aphthous stomatitis.
Strabismus
Binding of the cyclophilin 40 ortholog SQUINT to Hsp90 protein is required for SQUINT function in Arabidopsis.
Streptococcal Infections
Molecular cloning, purification and immunological responses of recombinants GroEL and DnaK from Streptococcus pyogenes.
Stroke
70-kDa Heat Shock Protein Downregulates Dynamin in Experimental Stroke: A New Therapeutic Target?
Stroke
A prospective evaluation of the heat shock protein 70 gene polymorphisms and the risk of stroke.
Stroke
Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke.
Stroke
Atherosclerosis as a paradigmatic disease of the elderly: role of the immune system.
Stroke
C-Terminus of HSC70 Interacting Protein Increases Following Stroke and Impairs Survival Against Acute Oxidative Stress.
Stroke
Calorie restriction and stroke.
Stroke
Can L-glutamine augmented heat shock protein 70 expression prevent exercise-induced exertional heat stroke and sudden cardiac death?
Stroke
Cerebrovascular dysfunction is an attractive target for therapy in heat stroke.
Stroke
Characterization of heat shock protein 27 in extracellular vesicles: a potential anti-inflammatory therapy.
Stroke
Cofilin-actin rod formation in experimental stroke is attenuated by therapeutic hypothermia and overexpression of the inducible 70 kD inducible heat shock protein (Hsp70).
Stroke
Decreasing or increasing heat shock protein 72 exacerbates or attenuates heat-induced cell death, respectively, in rat hypothalamic cells.
Stroke
Diazoxide increases liver and kidney HSP25 and HSP70 after shock and stroke.
Stroke
Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions.
Stroke
Dimeric heat shock protein 40 binds radial spokes for generating coupled power strokes and recovery strokes of 9 + 2 flagella.
Stroke
Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse.
Stroke
Exercise preconditioning reduces neuronal apoptosis in stroke by up-regulating heat shock protein-70 (heat shock protein-72) and extracellular-signal-regulated-kinase 1/2.
Stroke
Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy.
Stroke
Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.
Stroke
Heat shock protein 70 and AMP-activated protein kinase contribute to 17-DMAG-dependent protection against heat stroke.
Stroke
Heat shock protein linked to stroke protection.
Stroke
Heat shock proteins and neuroprotection.
Stroke
Immune-mediated mechanisms of endothelial damage in atherosclerosis.
Stroke
Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4- and MyD88-dependent pathway.
Stroke
Localization of 70-kDa stress protein induction in gerbil brain after ischemia.
Stroke
Micro-RNA-30a regulates ischemia-induced cell death by targeting heat shock protein HSPA5 in primary cultured cortical neurons and mouse brain after stroke.
Stroke
miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo.
Stroke
Molecular chaperones: Toward new therapeutic tools.
Stroke
Molecular targets in cerebral ischemia for developing novel therapeutics.
Stroke
Neuron-Specific Enolase, S100 Calcium-Binding Protein B, and Heat Shock Protein 70 Levels in Patients With Intracranial Hemorrhage.
Stroke
Novel inflammatory biomarkers and their correlation to Chlamydia pneumoniae titres in acute ischemic stroke.
Stroke
Overexpression of heat shock protein 72 attenuates NF-?B activation using a combination of regulatory mechanisms in microglia.
Stroke
Oxidative stress and ischemic injuries in heat stroke.
Stroke
Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury.
Stroke
Presence of heat shock protein 70 in secondary lymphoid tissue correlates with stroke prognosis.
Stroke
Role of Cytotoxic Protease Granzyme-b in Neuronal Degeneration during Human Stroke.
Stroke
Serum High-Sensitivity C-Reactive Protein and Heat Shock Protein 27 Antibody Titers in Patients With Stroke and 6-Month Prognosis.
Stroke
Serum levels of heat shock protein 27 in patients with acute ischemic stroke.
Stroke
Stem Cell-Like Dog Placenta Cells Afford Neuroprotection against Ischemic Stroke Model via Heat Shock Protein Upregulation.
Stroke
The 70-kDa heat shock protein (Hsp70) as a therapeutic target for stroke.
Stroke
The Association between Inflammatory Markers in the Acute Phase of Stroke and Long-Term Stroke Outcomes: Evidence from a Population-Based Study of Stroke.
Stroke
The Broad Stroke of Hsp90 Inhibitors: Painting over the RAF Inhibitor Paradox.
Stroke
The Effects of Mouse Recombinant Resistin on mRNA Expression of Proinflammatory and Anti-Inflammatory Cytokines and Heat Shock Protein-70 in Experimental Stroke Model.
Stroke
The Hsp90 Inhibitor 17-DMAG Attenuates Hyperglycemia-Enhanced Hemorrhagic Transformation in Experimental Stroke.
Stroke
The neuroprotective potential of heat shock protein 70 (HSP70).
Stroke
The power stroke of the DnaK/DnaJ/GrpE molecular chaperone system.
Stroke
The role of heat shock protein 70 in the protective effect of YC-1 on heat stroke rats.
Stroke
The stress response: implications for the clinical development of hsp90 inhibitors.
Stroke
[Distribution of 70kDa heat shock protein in rabbit brains after heat stress and heat stroke]
Strongyloidiasis
Structural and functional characterization of a novel scFv anti-HSP60 of Strongyloides sp.
Subarachnoid Hemorrhage
Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1? signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats.
Subarachnoid Hemorrhage
Heat shock protein expression in cerebral vessels after subarachnoid hemorrhage.
Subarachnoid Hemorrhage
Heat Shock Protein Expression in Cerebral Vessels after Subarachnoid Hemorrhage.
Subarachnoid Hemorrhage
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Subarachnoid Hemorrhage
Neuroprotective Effects of Valproic Acid on Blood-Brain Barrier Disruption and Apoptosis-Related Early Brain Injury in Rats Subjected to Subarachnoid Hemorrhage Are Modulated by Heat Shock Protein 70/Matrix Metalloproteinases and Heat Shock Protein 70/AKT Pathways.
Subarachnoid Hemorrhage
Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage.
Sudden Unexpected Death in Epilepsy
Sudden and unexpected death in epilepsy (SUDEP): evidence of acute neuronal injury using HSP-70 and c-Jun immunohistochemistry.
Sunburn
Increased expression of the 72-kDa heat shock protein and reduced sunburn cell formation in human skin after local hyperthermia.
Sunburn
Prevention of the ultraviolet effects on clinical and histopathological changes, as well as the heat shock protein-70 expression in mouse skin by topical application of algal UV-absorbing compounds.
Supranuclear Palsy, Progressive
The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration.
Synovitis
A synthetic mycobacterial heat shock peptide prevents adjuvant arthritis but not proteoglycan-induced synovitis in the rat.
Synovitis
Chaperonin 60 regulation of SOX9 ubiquitination mitigates the development of knee osteoarthritis.
Synucleinopathies
Convergence of Heat Shock Protein 90 with Ubiquitin in Filamentous {alpha}-Synuclein Inclusions of {alpha}-Synucleinopathies.
Synucleinopathies
Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies.
Synucleinopathies
Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies.
Synucleinopathies
The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy.
Systemic Vasculitis
Human HSP 60 peptide responsive T cell lines are similarly present in both Behçet's disease patients and healthy controls.
Tachycardia
Exogenous heat shock cognate protein 70 pretreatment attenuates cardiac and hepatic dysfunction with associated anti-inflammatory responses in experimental septic shock.
Tachycardia
HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes.
Takayasu Arteritis
Cellular and humoral immune responses to mycobacterial heat shock protein-65 and its human homologue in Takayasu's arteritis.
Takayasu Arteritis
Raised agalactosyl IgG and antimycobacterial humoral immunity in Takayasu's arteritis.
Takayasu Arteritis
Reactivity of gamma/delta T cells to human 60-kd heat-shock protein and their cytotoxicity to aortic endothelial cells in Takayasu arteritis.
Takayasu Arteritis
Takayasu's arteritis: role of Mycobacterium tuberculosis and its 65 kDa heat shock protein.
Tauopathies
Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.
Tauopathies
Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
Tauopathies
Imbalance of Hsp70 family variants fosters tau accumulation.
Tauopathies
Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies.
Tauopathies
Intraneuronal accumulation of misfolded tau protein induces overexpression of Hsp27 in activated astrocytes.
Tauopathies
Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement.
Tauopathies
Low endogenous and chemical induced heat shock protein induction in a 0N3Rtau-expressing Drosophila larval model of Alzheimer's disease.
Tauopathies
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Tauopathies
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.
Tauopathies
Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels.
Tauopathies
Tau phosphorylation, molecular chaperones, and ubiquitin E3 ligase: clinical relevance in Alzheimer's disease.
Tauopathies
Tau Triage Decisions Mediated by the Chaperone Network.
Tauopathies
The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics.
Tauopathies
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.
Tauopathies
The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics.
TDP-43 Proteinopathies
Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies.
Tendinopathy
Heat shock protein and apoptosis in supraspinatus tendinopathy.
Tendinopathy
Photobiomodulation therapy on expression of HSP70 protein and tissue repair in experimental acute Achilles tendinitis.
Teratocarcinoma
A binding site for the cyclic adenosine 3',5'-monophosphate-response element-binding protein as a regulatory element in the grp78 promoter.
Teratocarcinoma
ER Stress-Mediated Apoptotic Pathway Induced by Amyloid-beta.
Testicular Neoplasms
Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
Testicular Neoplasms
Testicular superoxide dismutase activity, heat shock protein 70 concentration and blood plasma inhibin-alpha concentration of dogs with a Sertoli cell tumor in a unilateral cryptorchid testis.
Tetanus
1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543).
Tetanus
Absence of peripheral blood T cell responses to "shared epitope' containing peptides in recent onset rheumatoid arthritis.
Tetanus
Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop.
Tetanus
Depressed proliferative responses by peripheral blood mononuclear cells from early arthritis patients to mycobacterial heat shock protein 60.
Tetanus
Humoral response against heat shock proteins and other mycobacterial antigens after intravesical treatment with bacille Calmette-Guérin (BCG) in patients with superficial bladder cancer.
Tetanus
Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical type I diabetes.
Tetanus
Immunomodulatory effects of radiofrequency ablation in a breast cancer model.
Tetanus
Spinal fluid lymphocytes from a subgroup of multiple sclerosis patients respond to mycobacterial antigens.
Tetanus
Th1 and Th2 cell responses of type 1 diabetes patients and healthy controls to human heat-shock protein 60 peptides AA437-460 and AA394-408.
Tetralogy of Fallot
Expression of proto-oncogenes, genes for muscle specific isoforms and heat shock protein (HSP) -70 gene in hypertrophied cardiac muscles from patients with atrial septal defect or tetralogy of Fallot.
Tetralogy of Fallot
Heat shock protein 27 is increased in cyanotic tetralogy of Fallot myocardium and is associated with improved cardiac output and contraction.
Tetralogy of Fallot
Myocardial expression of heat shock protein 70i protects early postoperative right ventricular function in cyanotic tetralogy of Fallot.
Thalassemia
Increased Serum Heat Shock Protein 27 Antibody Titers and Prooxidant-Antioxidant Balance in Patients with Beta-Thalassemia Major.
Thrombocythemia, Essential
Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage.
Thrombocythemia, Essential
The role of calreticulin mutations in myeloproliferative neoplasms.
Thrombocytopenia
Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex.
Thrombocytopenia
Platelet count correlates with stage and predicts survival in melanoma.
Thrombocytosis
Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors.
Thrombocytosis
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.
Thrombocytosis
Molecular pathogenesis of myelodysplastic syndromes with deletion 5q.
Thrombosis
Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis.
Thrombosis
HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
Thrombosis
Mechanism of collagen-induced release of 5-HT, PDGF-AB and sCD40L from human platelets: role of HSP27 phosphorylation via p44/p42 MAPK.
Thrombosis
Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78.
Thrombosis
[Research Progress on Inflammasome and Cancer-associated Thrombosis-Review].
Thymoma
Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors.
Thymoma
LOXL1?AS1 promotes thymoma and thymic carcinoma progression by regulating miR?525?5p?HSPA9.
Thymoma
Matrin 3 co-immunoprecipitates with the heat shock proteins glucose-regulated protein 78 (GRP78), GRP75 and glutathione S-transferase ? isoform 2 (GST?2) in thymoma cells.
Thymus Neoplasms
Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses.
Thyroid Cancer, Papillary
Concomitant high expression of ER?36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior.
Thyroid Cancer, Papillary
Destabilizing RET in targeted treatment of thyroid cancers.
Thyroid Cancer, Papillary
HIF-1? and HSP90: Target molecules selected from a tumorigenic papillary thyroid carcinoma cell line.
Thyroid Cancer, Papillary
HSP90 inhibitor NVP-AUY922 induces cell apoptosis by disruption of the survivin in papillary thyroid carcinoma cells.
Thyroid Cancer, Papillary
Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells.
Thyroid Cancer, Papillary
The Relationship of Immunoexpression of Ki-67 and Hsp70 with Clinical and Morphological Parameters and Prognosis of Papillary Thyroid Cancer.
Thyroid Carcinoma, Anaplastic
17-Allylamino-17-demethoxygeldanamycin and Herbimycin A Induce Cell Death by Modulating ?-Catenin and PI3K/AKT Signaling in FRO Anaplastic Thyroid Carcinoma Cells.
Thyroid Carcinoma, Anaplastic
Effect of mesoporous silica nanoparticles co?loading with 17?AAG and Torin2 on anaplastic thyroid carcinoma by targeting VEGFR2.
Thyroid Carcinoma, Anaplastic
Herbimycin A inhibits cell growth with reversal of epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells.
Thyroid Carcinoma, Anaplastic
Hsp70 inhibition potentiates radicicol-induced cell death in anaplastic thyroid carcinoma cells.
Thyroid Carcinoma, Anaplastic
Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells.
Thyroid Carcinoma, Anaplastic
Novel Heat Shock Protein 90 Inhibitor NVP-AUY922 Synergizes With the Histone Deacetylase Inhibitor PXD101 in Induction of Death of Anaplastic Thyroid Carcinoma Cells.
Thyroid Carcinoma, Anaplastic
Novel HSP90 inhibitors effectively target functions of thyroid cancer stem cell preventing migration and invasion.
Thyroid Carcinoma, Anaplastic
The effect of 17-allylamino-17-demethoxygeldanamycin alone or in combination with paclitaxel on anaplastic thyroid carcinoma cells.
Thyroid Carcinoma, Anaplastic
The heat shock protein 90 inhibitor SNX5422 has a synergistic activity with histone deacetylase inhibitors in induction of death of anaplastic thyroid carcinoma cells.
Thyroid Diseases
Analysis of heat shock protein polymorphisms in a large family with autoimmune thyroid diseases.
Thyroid Diseases
Anti 70 kDa heat shock protein antibodies in sera of patients affected by autoimmune and non-autoimmune thyroid diseases.
Thyroid Diseases
Detection of autoantibodies to the pancreatic islet heat shock protein 60 in insulin-dependent diabetes mellitus.
Thyroid Diseases
Immunohistochemical detection and localization of a 72-kilodalton heat shock protein in autoimmune thyroid disease.
Thyroid Diseases
Methimazole and propylthiouracil inhibit the oxygen free radical-induced expression of a 72 kilodalton heat shock protein in Graves' retroocular fibroblasts.
Thyroid Neoplasms
17-Allylamino-17-demethoxygeldanamycin activity against thyroid cancer cell lines correlates with heat shock protein 90 levels.
Thyroid Neoplasms
A novel heat shock protein inhibitor KU757 with efficacy in lenvatinib-resistant follicular thyroid cancer cells overcomes up-regulated glycolysis in drug-resistant cells in vitro.
Thyroid Neoplasms
A novel HSP90 modulator with selective activity against thyroid cancers in vitro.
Thyroid Neoplasms
Destabilizing RET in targeted treatment of thyroid cancers.
Thyroid Neoplasms
Different induction of GRP78 and CHOP as a predictor of sensitivity to proteasome inhibitors in thyroid cancer cells.
Thyroid Neoplasms
Efficacy of an HSP90 inhibitor, ganetespib, in preclinical thyroid cancer models.
Thyroid Neoplasms
Function of HSP90 and p23 in the telomerase complex of thyroid tumors.
Thyroid Neoplasms
Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells.
Thyroid Neoplasms
Heat shock proteins HSP90, HSP70 and GRP78 expression in medullary thyroid carcinoma.
Thyroid Neoplasms
IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.
Thyroid Neoplasms
Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells.
Thyroid Neoplasms
Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells.
Thyroid Neoplasms
Novel HSP90 inhibitors effectively target functions of thyroid cancer stem cell preventing migration and invasion.
Thyroid Neoplasms
Nucleotide receptors stimulation by extracellular ATP controls Hsp90 expression through APE1/Ref-1 in thyroid cancer cells: a novel tumorigenic pathway.
Thyroid Neoplasms
Quercetin-Induced Cell Death in Human Papillary Thyroid Cancer (B-CPAP) Cells.
Thyroid Neoplasms
Synergistic cytotoxicity of BIIB021 with triptolide through suppression of PI3K/Akt/mTOR and NF-?B signal pathways in thyroid carcinoma cells.
Thyroid Neoplasms
The dipeptidyl peptidase-IV inhibitor gemigliptin alone or in combination with NVP-AUY922 has a cytotoxic activity in thyroid carcinoma cells.
Thyroid Neoplasms
The heat shock protein 90-binding geldanamycin inhibits cancer cell proliferation, down-regulates oncoproteins, and inhibits epidermal growth factor-induced invasion in thyroid cancer cell lines.
Thyroid Neoplasms
Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma.
Thyroiditis
Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto's thyroiditis patients based on the response of their PBMC with IL-2 and IFN-? secretion to stimulation with Hsp60.
Thyroiditis
Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis.
Thyroiditis
Induction in vitro of 72-kD heat shock protein in a continuous culture of rat thyroid cells, FRTL5.
Thyroiditis
Sequence homologies between hsp60 and autoantigens.
Tics
Cell surface GRP78 promotes stemness in normal and neoplastic cells.
Tics
Novel C-terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self-renewal, and epithelial-mesenchymal transition.
Tics
Suppression of Esophageal Cancer Stem-like Cells by SNX-2112 Is Enhanced by STAT3 Silencing.
Tinea
Heat Shock Protein 90 (Hsp90) as a Molecular Target for the Development of Novel Drugs Against the Dermatophyte Trichophyton rubrum.
Tinea
Isolation and characterization of an immunogenic fragment of heat shock protein 60 from Trichophyton mentagrophytes.
Tinea
Recombinant protein and DNA vaccines derived from hsp60 Trichophyton mentagrophytes control the clinical course of trichophytosis in bovine species and guinea-pigs.
Tinnitus
Western blot immunoassay for HSP-70 antibodies in idiopathic tinnitus: a preliminary report.
Tongue Neoplasms
Prognostic evaluation of p53, heat shock protein 70, Ki67, and CD34 expression in cancer of the tongue in Tunisia.
Tonsillitis
Relationship of endoplasmic reticulum stress with the etiopathogenesis of chronic tonsillitis and tonsillar hypertrophy in pediatric patients: a prospective, parallel-group study.
Tooth Diseases
Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27-induced Charcot Marie Tooth Disease.
Tooth Loss
Tooth Loss Induces Memory Impairment and Gliosis in App Knock-In Mouse Models of Alzheimer's Disease.
Toxic Optic Neuropathy
A rat retinal damage model predicts for potential clinical visual disturbances induced by Hsp90 inhibitors.
Toxic Optic Neuropathy
Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.
Toxic Optic Neuropathy
TAS-116, a highly selective inhibitor of heat shock protein 90? and ?, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models.
Toxic Optic Neuropathy
TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells.
Toxoplasmosis
Contribution of 65-kDa heat shock protein induced by gamma and delta T cells to protection against Toxoplasma gondii infection.
Toxoplasmosis
Immune Responses Induced by HSP60 DNA Vaccine against Toxoplasma gondii Infection in Kunming Mice.
Toxoplasmosis
Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice.
Toxoplasmosis
Induction of heat shock protein closely correlates with protection against Toxoplasma gondii infection.
Toxoplasmosis
Induction of protective immunity by DNA vaccination with Toxoplasma gondii HSP70, HSP30 and SAG1 genes.
Toxoplasmosis
Roles of NKT cells in resistance against infection with Toxoplasma gondii and in expression of heat shock protein 65 in the host macrophages.
Toxoplasmosis
Use of immunological methods to the detection of toxoplasmosis and heat shock protein HSP70 in men.
Tracheal Stenosis
Preproenkephalin gene expression in the rat cerebral cortex during chronic tracheal stenosis.
Trachoma
Characterization of humoral immune responses to chlamydial HSP60, CPAF, and CT795 in inflammatory and severe trachoma.
Trachoma
Immune response to chlamydial 60-kilodalton heat shock protein in tears from Nepali trachoma patients.
Trachoma
Multiple Chlamydiaceae species in trachoma: implications for disease pathogenesis and control.
Trachoma
Persistent Chlamydia trachomatis infections resist apoptotic stimuli.
Trauma, Nervous System
Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions.
Trauma, Nervous System
Heat Shock Protein 70 (HSP70) Induction: Chaperonotherapy for Neuroprotection after Brain Injury.
Trauma, Nervous System
Hyperthermia assists survival of astrocytes from oxidative-mediated necrotic cell death.
Trauma, Nervous System
Interaction of ethanol with inducers of glucose-regulated stress proteins. Ethanol potentiates inducers of grp78 transcription.
Tremor
Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease.
Triple Negative Breast Neoplasms
?B-crystallin: a novel regulator of breast cancer metastasis to the brain.
Triple Negative Breast Neoplasms
A novel chalcone-based molecule, BDP inhibits MDA?MB?231 triple-negative breast cancer cell growth by suppressing Hsp90 function.
Triple Negative Breast Neoplasms
C-terminal HSP90 inhibitor L80 elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Triple Negative Breast Neoplasms
Chemotherapy Controls Metastasis Through Stimulatory Effects on GRP78 and Its Transcription Factor CREB3L1.
Triple Negative Breast Neoplasms
Chemotherapy Sensitizes Therapy-Resistant Cells to Mild Hyperthermia by Suppressing Heat Shock Protein 27 Expression in Triple-Negative Breast Cancer.
Triple Negative Breast Neoplasms
Erratum: The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Expression of glucose-regulated protein 78 as prognostic biomarkers for triple-negative breast cancer.
Triple Negative Breast Neoplasms
FOXP2 promotes tumor proliferation and metastasis by targeting GRP78 in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Heat shock protein 90? inhibitor, PU-H71 in combination with DHEA promoting apoptosis in triple-negative breast cancer cell line MDA-MB-231.
Triple Negative Breast Neoplasms
HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Hsp90 Inhibition Results in Glucocorticoid Receptor Degradation in Association with Increased Sensitivity to Paclitaxel in Triple-Negative Breast Cancer.
Triple Negative Breast Neoplasms
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models.
Triple Negative Breast Neoplasms
Inhibition of HSP90 sensitizes a novel Raf/ERK dual inhibitor CY-9d in triple-negative breast cancer cells.
Triple Negative Breast Neoplasms
Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.
Triple Negative Breast Neoplasms
MicroPET/CT Imaging of AXL Downregulation by HSP90 Inhibition in Triple-Negative Breast Cancer.
Triple Negative Breast Neoplasms
Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells.
Triple Negative Breast Neoplasms
Preclinical activity profile and therapeutic efficacy of the HSP90 inhibitor ganetespib in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Radiosynthesis, biological evaluation and preliminary microPET study of 18F-labeled 5-resorcinolic triazolone derivative based on ganetespib targeting HSP90.
Triple Negative Breast Neoplasms
Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I.
Triple Negative Breast Neoplasms
Simvastatin functions as a heat shock protein 90 inhibitor against triple-negative breast cancer.
Triple Negative Breast Neoplasms
The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer.
Truncus Arteriosus, Persistent
Type 2 diabetes mellitus induces congenital heart defects in murine embryos by increasing oxidative stress, endoplasmic reticulum stress and apoptosis.
Trypanosomiasis
Heat shock protein 90 as a potential drug target against surra.
Trypanosomiasis
Post-transcriptional repair of a split heat shock protein 90 gene by mRNA trans-splicing.
Trypanosomiasis, African
Model System Identifies Kinetic Driver of Hsp90 Inhibitor Activity against African Trypanosomes and Plasmodium falciparum.
Trypanosomiasis, African
Overproduction, purification and characterisation of Tbj1, a novel Type III Hsp40 from Trypanosoma brucei, the African sleeping sickness parasite.
Trypanosomiasis, African
Protein phosphatase 5 is required for Hsp90 function during proteotoxic stresses in Trypanosoma brucei.
Tuberculosis
16 kDa heat shock protein from heat-inactivated Mycobacterium tuberculosis is a homodimer - suitability for diagnostic applications with specific llama VHH monoclonals.
Tuberculosis
A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis.
Tuberculosis
A broad set of different llama antibodies specific for a 16 kDa heat shock protein of Mycobacterium tuberculosis.
Tuberculosis
A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue.
Tuberculosis
A DNA vaccine against tuberculosis based on the 65 kDa heat-shock protein differentially activates human macrophages and dendritic cells.
Tuberculosis
A dominant human leucocyte antigen DR4-Dw15 restricted mycobacterial 65 kDa antigen-specific T-cell immunity in Chinese patients with rheumatoid arthritis.
Tuberculosis
A gene from Mycobacterium tuberculosis which is homologous to the DnaJ heat shock protein of E. coli.
Tuberculosis
A Humanized Monoclonal Antibody against Heat Shock Protein 60 Suppresses Murine Arthritis and Colitis and Skews the Cytokine Balance toward an Anti-Inflammatory Response.
Tuberculosis
A large fraction of human peripheral blood gamma/delta + T cells is activated by Mycobacterium tuberculosis but not by its 65-kD heat shock protein.
Tuberculosis
A Mycobacterium tuberculosis mutant lacking the groEL homologue cpn60.1 is viable but fails to induce an inflammatory response in animal models of infection.
Tuberculosis
A novel antigen-carrier system: the Mycobacterium tuberculosis Acr protein carried by raw starch microparticles.
Tuberculosis
A novel atherogenic epitope from Mycobacterium tuberculosis heat shock protein 65 enhances atherosclerosis in rabbit and LDL receptor-deficient mice.
Tuberculosis
A novel MtHSP70-FPR1 fusion protein enhances cytotoxic T lymphocyte responses to cervical cancer cells by activating human monocyte-derived dendritic cells via the p38 MAPK signaling pathway.
Tuberculosis
A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma.
Tuberculosis
A novel nucleoid-associated protein of Mycobacterium tuberculosis is a sequence homolog of GroEL.
Tuberculosis
A Novel Therapeutic and Prophylactic Vaccine (HVJ-Envelope / Hsp65 DNA + IL-12 DNA) against Tuberculosis Using the Cynomolgus Monkey Model.
Tuberculosis
A Novel Therapeutic and Prophylactic Vaccine against Tuberculosis Using the Cynomolgus Monkey Model and Mouse Model.
Tuberculosis
A peptide binding motif for I-Eg7, the MHC class II molecule that protects E alpha-transgenic nonobese diabetic mice from autoimmune diabetes.
Tuberculosis
A synthetic 10-kD heat shock protein (hsp10) from Mycobacterium tuberculosis modulates adjuvant arthritis.
Tuberculosis
A synthetic dengue virus antigen elicits enhanced antibody titers when linked to, but not mixed with, Mycobacterium tuberculosis HSP70 domain II.
Tuberculosis
A truncated C-terminal fragment of Mycobacterium tuberculosis HSP70 enhances cell-mediated immune response and longevity of the total IgG to influenza A virus M2e protein in mice.
Tuberculosis
Activation of T cells recognizing an epitope of heat-shock protein 70 can protect against rat adjuvant arthritis.
Tuberculosis
Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis.
Tuberculosis
Age-associated changes in the proliferative response of rat intestinal intraepithelial leukocytes to bacterial antigens.
Tuberculosis
Alpha-crystallin promotes assembly of a trimeric form of Mycobacterium tuberculosis Hsp16.3 in a cell free system.
Tuberculosis
Anti-Hsp65 antibodies recognize M proteins of group A streptococci.
Tuberculosis
Antibodies against C-reactive protein cross-react with 60-kilodalton heat shock proteins.
Tuberculosis
Antibodies to mycobacterial 65 kDa heat shock protein in systemic sclerosis (scleroderma).
Tuberculosis
Antibody levels to mycobacteria in relation to HLA type: evidence for non-HLA-linked high levels of antibody to the 65 kD heat shock protein of M. bovis in rheumatoid arthritis.
Tuberculosis
Antibody to Mycobacterium tuberculosis 65 kDa heat shock protein in patients with rheumatoid arthritis--a survey of antigen-specific antibody isotypes and subclasses in an endemic area of previous tuberculosis infection.
Tuberculosis
Assays for adjuvanticity of new formulations and of carrier proteins for inducing antibody responses to selected immunogens in the squirrel monkey Saimiri sciureus.
Tuberculosis
Association between the 65-kilodalton heat shock protein, Streptococcus sanguis, and the corresponding antibodies in Behçet's syndrome.
Tuberculosis
Association of strong immune responses to PPE protein Rv1168c with active tuberculosis.
Tuberculosis
Autoantibodies to human heat shock protein (hsp)60 may be induced by Escherichia coli groEL.
Tuberculosis
Bacterial heat shock proteins directly induce cytokine mRNA and interleukin-1 secretion in macrophage cultures.
Tuberculosis
Bacterial luciferase is naturally destabilized in Mycobacterium tuberculosis and can be used to monitor changes in gene expression.
Tuberculosis
Bacterial thymidine kinase as a non-invasive imaging reporter for Mycobacterium tuberculosis in live animals.
Tuberculosis
BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis-infected macrophages through selective autophagy.
Tuberculosis
Bb65, a major immunoreactive protein of Bartonella bacilliformis.
Tuberculosis
BCG and BCG/DNAhsp65 vaccinations promote protective effects without deleterious consequences for experimental autoimmune encephalomyelitis.
Tuberculosis
Biochemical characterization of ClpB protein from Mycobacterium tuberculosis and identification of its small-molecule inhibitors.
Tuberculosis
Biotechnology in the development of new vaccines and diagnostic reagents against tuberculosis.
Tuberculosis
Boosting with recombinant vaccinia increases HPV-16 E7-Specific T cell precursor frequencies and antitumor effects of HPV-16 E7-expressing Sindbis virus replicon particles.
Tuberculosis
C-terminal heat shock protein 70 of Mycobacterium tuberculosis as a molecular adjuvant for DNA vaccination with the porcine circovirus type 2 ORF2 (capsid) gene in mice.
Tuberculosis
Cell-mediated immune responses and protective efficacy against infection with Mycobacterium tuberculosis induced by Hsp65 and hIL-2 fusion protein in mice.
Tuberculosis
Change in kinetic regime of protein aggregation with temperature increase. Thermal aggregation of rabbit muscle creatine kinase.
Tuberculosis
Characterization of a 54-kDa heat-shock-inducible protein of Pasteurella haemolytica.
Tuberculosis
Characterization of a novel heat shock protein (Hsp22.5) involved in the pathogenesis of Mycobacterium tuberculosis.
Tuberculosis
Characterization of HPV-16 E6 DNA vaccines employing intracellular targeting and intercellular spreading strategies.
Tuberculosis
Characterization of prominent protein antigens from mycobacteria.
Tuberculosis
Chlamydial disease pathogenesis. The 57-kD chlamydial hypersensitivity antigen is a stress response protein.
Tuberculosis
Cloning and expression of malaria and tuberculosis epitopes in mycobacterium bovis bacille calmette-guérin.
Tuberculosis
Common antigens prediction in bacterial bioweapons: a perspective for vaccine design.
Tuberculosis
Comparative analysis of effects of cytokine gene adjuvants on DNA vaccination against Mycobacterium tuberculosis heat shock protein 65.
Tuberculosis
Comparison of HPV DNA vaccines employing intracellular targeting strategies.
Tuberculosis
Comparison of polymerase chain reaction amplification of two mycobacterial DNA sequences, IS6110 and the 65kDa antigen gene, in the diagnosis of tuberculosis.
Tuberculosis
Comparison of the CD8+ T cell responses and antitumor effects generated by DNA vaccine administered through gene gun, biojector, and syringe.
Tuberculosis
Comparison of the mucosal adjuvanticities of two Toll-like receptor ligands for recombinant adenovirus-delivered African swine fever virus fusion antigens.
Tuberculosis
Comprehensive gene expression profiling in lungs of mice infected with Mycobacterium tuberculosis following DNAhsp65 immunotherapy.
Tuberculosis
Construction and evaluation of luciferase reporter phages for the detection of active and non-replicating tubercle bacilli.
Tuberculosis
Construction, expression and identification of a recombinant BCG vaccine encoding human mycobacterium tuberculosis heat shock protein 65.
Tuberculosis
Contrasting evolutionary rates in the duplicate chaperonin genes of Mycobacterium tuberculosis and M. leprae.
Tuberculosis
Critical role of TRIF and MyD88 in Mycobacterium tuberculosis Hsp70-mediated activation of dendritic cells.
Tuberculosis
Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis.
Tuberculosis
Cross-reactivity of anti-10kD heat shock protein antibodies in leprosy and tuberculosis patients.
Tuberculosis
Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis.
Tuberculosis
Cytokine production and cytotoxicity mediated by CD4+ T cells from healthy subjects vaccinated with Mycobacterium bovis BCG and from pulmonary tuberculosis patients.
Tuberculosis
Dehydroepiandrosterone sulphate enhances IgG and Interferon-gamma production during immunization to tuberculosis in young but not aged mice.
Tuberculosis
Design and Construction of a Cloning Vector Containing the hspX Gene of Mycobacterium tuberculosis.
Tuberculosis
Detection of 65 kD heat shock protein in cerebrospinal fluid of tuberculous meningitis patients.
Tuberculosis
Detection of mycobacterial DNA in sarcoidosis and tuberculosis with polymerase chain reaction.
Tuberculosis
Determination of the sensitivity and specificity of PCR assays using different target dnas for the detection of Mycobacterium tuberculosis.
Tuberculosis
Diagnostic markers for tuberculosis ascites: a preliminary study.
Tuberculosis
Dietary restriction abrogates antibody production induced by a DNA vaccine encoding the mycobacterial 65 kDa heat shock protein.
Tuberculosis
Differential mycobacterial 65-kDa heat shock protein T cell epitope recognition after adjuvant arthritis-inducing or protective immunization protocols.
Tuberculosis
Differential regulation of Th1 and Th2 cells by p91-110 and p21-40 peptides of the 16-kD alpha-crystallin antigen of Mycobacterium tuberculosis.
Tuberculosis
Differentiation between Mycobacterium tuberculosis and Mycobacterium bovis by a multiplex-polymerase chain reaction.
Tuberculosis
Distribution of non-tuberculosis mycobacteria strains from suspected tuberculosis patients by heat shock protein 65 PCR-RFLP.
Tuberculosis
DNA amplification and reverse dot blot hybridization for detection and identification of mycobacteria to the species level in the clinical laboratory.
Tuberculosis
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes.
Tuberculosis
DNA vaccine using hemagglutinating virus of Japan-liposome encapsulating combination encoding mycobacterial heat shock protein 65 and interleukin-12 confers protection against Mycobacterium tuberculosis by T cell activation.
Tuberculosis
Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis.
Tuberculosis
DR alpha: E beta heterodimers in DRA transgenic mice hinder expression of E alpha: E beta molecules and are more efficient in antigen presentation.
Tuberculosis
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.
Tuberculosis
Early appearing gamma/delta-bearing T cells during infection with Calmétte Guérin bacillus.
Tuberculosis
Effects of Mycobacterium tuberculosis Mutant Strain Hsp16.3 Gene on Murine RAW 264.7 Macrophage Autophagy.
Tuberculosis
Electrostatic interactions play a critical role in Mycobacterium tuberculosis Hsp16.3 binding of substrate proteins.
Tuberculosis
Enhanced immunity against hepatoma induced by dendritic cells pulsed with Hsp70-H22 peptide complexes and CD40L.
Tuberculosis
Enhanced protective efficacy against tuberculosis provided by a recombinant urease deficient BCG expressing heat shock protein 70-major membrane protein-II having PEST sequence.
Tuberculosis
Enhancement of DNA vaccine potency by coadministration of a tumor antigen gene and DNA encoding serine protease inhibitor-6.
Tuberculosis
Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene.
Tuberculosis
Enhancement of Sindbis virus self-replicating RNA vaccine potency by linkage of Mycobacterium tuberculosis heat shock protein 70 gene to an antigen gene.
Tuberculosis
Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen.
Tuberculosis
Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X.
Tuberculosis
Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life with intracellular targeting strategies.
Tuberculosis
Evaluation of a novel vaccine (HVJ-liposome/HSP65 DNA+IL-12 DNA) against tuberculosis using the cynomolgus monkey model of TB.
Tuberculosis
Evaluation of heat shock proteins for discriminating between latent tuberculosis infection and active tuberculosis: A preliminary report.
Tuberculosis
Evaluation of highly conserved hsp65-specific nested PCR primers for diagnosing Mycobacterium tuberculosis.
Tuberculosis
Evaluation of the LiPA MYCOBACTERIA assay for identification of mycobacterial species from BACTEC 12B bottles.
Tuberculosis
Expression of foreign gene in mycobacterium regulated by human Mycobacterium tuberculosis heat shock protein 70 promoter.
Tuberculosis
Facilitated oligomerization of mycobacterial GroEL: evidence for phosphorylation-mediated oligomerization.
Tuberculosis
Functional analysis of DR17(DR3)-restricted mycobacterial T cell epitopes reveals DR17-binding motif and enables the design of allele-specific competitor peptides.
Tuberculosis
Functional insights by comparison of modeled structures of 18kDa small heat shock protein and its mutant in Mycobacterium leprae.
Tuberculosis
Functional similarities between the small heat shock proteins Mycobacterium tuberculosis HSP 16.3 and human alphaB-crystallin.
Tuberculosis
Fused Mycobacterium tuberculosis multi-stage immunogens with an Fc-delivery system as a promising approach for the development of a tuberculosis vaccine.
Tuberculosis
Fusion Molecules of Heat Shock Protein HSPX with Other Antigens of Mycobacterium tuberculosis Show High Potential in Serodiagnosis of Tuberculosis.
Tuberculosis
Gamma delta T cell receptor analysis supports a role for HSP 70 selection of lymphocytes in multiple sclerosis lesions.
Tuberculosis
Generation of a T cell receptor (TCR)-like single domain antibody (sDAb) against a Mycobacterium Tuberculosis (Mtb) heat shock protein (HSP) 16kDa antigen presented by Human Leukocyte Antigen (HLA)-A*02.
Tuberculosis
Genetic vaccine for tuberculosis (pVAXhsp65) primes neonate mice for a strong immune response at the adult stage.
Tuberculosis
Green fluorescent protein as a marker for gene expression and cell biology of mycobacterial interactions with macrophages.
Tuberculosis
GroEL2 of Mycobacterium tuberculosis Reveals the Importance of Structural Pliability in Chaperonin Function.
Tuberculosis
Heat shock protein X purified from Mycobacterium tuberculosis enhances the efficacy of dendritic cells-based immunotherapy for the treatment of allergic asthma.
Tuberculosis
Heat shock protein-induced T-lymphocyte propagation from endomyocardial biopsies in heart transplantation.
Tuberculosis
Heat shock proteins and antigens of Mycobacterium tuberculosis.
Tuberculosis
Helminth coinfection does not affect therapeutic effect of a DNA vaccine in mice harboring tuberculosis.
Tuberculosis
High-resolution melting curve analysis of heat shock protein 65 for identification of mycobacterial isolates.
Tuberculosis
Highly persistent and effective prime/boost regimens against tuberculosis that use a multivalent modified vaccine virus Ankara-based tuberculosis vaccine with interleukin-15 as a molecular adjuvant.
Tuberculosis
HLA-DR3 molecules can bind peptides carrying two alternative specific submotifs.
Tuberculosis
Homology of the 70-kilodalton antigens from Mycobacterium leprae and Mycobacterium bovis with the Mycobacterium tuberculosis 71-kilodalton antigen and with the conserved heat shock protein 70 of eucaryotes.
Tuberculosis
Hsp16.3 of mycobacterium tuberculosis in exosomes as a biomarker of tuberculosis.
Tuberculosis
HSP60, HSP70 in the pathogenesis of Kawasaki disease: implication and action.
Tuberculosis
Human immune response to Mycobacterium tuberculosis antigens.
Tuberculosis
Identification and characterization of protective T cells in hsp65 DNA-vaccinated and Mycobacterium tuberculosis-infected mice.
Tuberculosis
Identification of bis-ANS binding sites in Mycobacterium tuberculosis small heat shock protein Hsp16.3: Evidences for a two-step substrate-binding mechanism.
Tuberculosis
Identification of HLA class II-restricted determinants of Mycobacterium tuberculosis-derived proteins by using HLA-transgenic, class II-deficient mice.
Tuberculosis
Identification of nontuberculous mycobacterial infection by IS6110 and hsp65 gene analysis on lung tissues.
Tuberculosis
Identification of the monocyte activating motif in Mycobacterium tuberculosis chaperonin 60.1.
Tuberculosis
Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progression.
Tuberculosis
Immune response induced by recombinant BCG expressing merozoite surface antigen 2 from Plasmodium falciparum.
Tuberculosis
Immunogenicity and protective efficacy of a DNA vaccine encoding the fusion protein of mycobacterium heat shock protein 65 (Hsp65) with human interleukin-2 against Mycobacterium tuberculosis in BALB/c mice.
Tuberculosis
Immunogenicity of a mycobacterial T-cell epitope expressed in outer membrane protein PhoE of Escherichia coli.
Tuberculosis
Immunological evaluation of a 12-kilodalton protein of Mycobacterium tuberculosis by enzyme-linked immunosorbent assay.
Tuberculosis
Immunomodulation and protection induced by DNA-hsp65 vaccination in an animal model of arthritis.
Tuberculosis
Immunotherapy of tuberculosis with Mycobacterium leprae Hsp65 as a DNA vaccine triggers cross-reactive antibodies against mammalian Hsp60 but not pathological autoimmunity.
Tuberculosis
Improved diagnosis of mycobacterial infections in formalin-fixed and paraffin-embedded sections with nested polymerase chain reaction.
Tuberculosis
Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein.
Tuberculosis
Induction of adjuvant arthritis in mice.
Tuberculosis
Induction of cellular immune reactions by A36, an antigen complex of Mycobacterium paratuberculosis: comparison of A36 and johnin components.
Tuberculosis
Influence of amino acids of a carrier protein flanking an inserted T cell determinant on T cell stimulation.
Tuberculosis
Introduction of 65 kDa antigen of Mycobacterium tuberculosis to cancer cells enhances anti-tumor effect of BCG therapy.
Tuberculosis
Is mycobacterial heat shock protein 16 kDa, a marker of the dormant stage of Mycobacterium tuberculosis, a sarcoid antigen?
Tuberculosis
Isolation and characterization of the groES and groEL genes of Bacillus subtilis Marburg.
Tuberculosis
Isolation, purification and preliminary X-ray characterization of Cpn60-2 (65 kDa heat-shock protein) from Mycobacterium tuberculosis.
Tuberculosis
Lack of protection in mice and necrotizing bronchointerstitial pneumonia with bronchiolitis in guinea pigs immunized with vaccines directed against the hsp60 molecule of Mycobacterium tuberculosis.
Tuberculosis
Legionella pneumophila htpAB heat shock operon: nucleotide sequence and expression of the 60-kilodalton antigen in L. pneumophila-infected HeLa cells.
Tuberculosis
Localisation of linear epitopes at the carboxy-terminal end of the mycobacterial 71 kDa heat shock protein.
Tuberculosis
Long-lasting specific antibodies against CETP induced by subcutaneous and mucosal administration of a 26-amino acid CETP epitope carried by heat shock protein 65 kDa in the absence of adjuvants.
Tuberculosis
Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection.
Tuberculosis
Marked conservation of complementarity-determining region 3 of the beta-chain of TCRs recognizing a mycobacterial heat shock protein 60-derived peptide with strong sequence similarity to human heat shock protein 60.
Tuberculosis
Menstrual Blood versus Endometrial Biopsy in Detection of Genital Tuberculosis by Using Nested Polymerase Chain Reaction in an Endemic Region.
Tuberculosis
Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein.
Tuberculosis
Modulatory effects of mycobacterial heat-shock protein 70 in DNA vaccination against lymphoma.
Tuberculosis
Molecular cloning and nucleotide sequence analysis of the gene encoding the immunoreactive Brucella abortus Hsp60 protein, BA60K.
Tuberculosis
Molecular cloning and sequencing of the circumsporozoite protein gene from Plasmodium falciparum strain FCC-1/HN and expression of the gene in Mycobacteria.
Tuberculosis
Molecular cloning and sequencing of the merozoite surface antigen 2 gene from Plasmodium falciparum strain FCC-1/HN and expression of the gene in mycobacteria.
Tuberculosis
MTBHsp70-exFPR1-pulsed Dendritic Cells Enhance the Immune Response against Cervical Cancer.
Tuberculosis
MtHsp70-CLIC1-pulsed dendritic cells enhance the immune response against ovarian cancer.
Tuberculosis
Multiple gene duplication and rapid evolution in the groEL gene: functional implications.
Tuberculosis
Murine and human B cell epitope mapping of the Mycobacterium tuberculosis 10-kD heat shock protein using overlapping peptides.
Tuberculosis
Mutational analysis of the mycobacteriophage BPs promoter PR reveals context-dependent sequences for mycobacterial gene expression.
Tuberculosis
Mycobacteria and human autoimmune disease: direct evidence of cross-reactivity between human lactoferrin and the 65-kilodalton protein of tubercle and leprosy bacilli.
Tuberculosis
Mycobacterial heat shock protein 65 mediated metabolic shift in decidualization of human endometrial stromal cells.
Tuberculosis
Mycobacterial Hsp65 antigen upregulates the cellular immune response of healthy individuals compared with tuberculosis patients.
Tuberculosis
Mycobacterium leprae-specific T cells from a tuberculoid leprosy patient suppress HLA-DR3-restricted T cell responses to an immunodominant epitope on 65-kDa hsp of mycobacteria.
Tuberculosis
Mycobacterium tuberculosis chaperonin 60.1 is a more potent cytokine stimulator than chaperonin 60.2 (Hsp 65) and contains a CD14-binding domain.
Tuberculosis
Mycobacterium tuberculosis ClpC1: characterization and role of the N-terminal domain in its function.
Tuberculosis
Mycobacterium tuberculosis complex in atherosclerosis.
Tuberculosis
Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin.
Tuberculosis
Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface.
Tuberculosis
Mycobacterium tuberculosis GroEL homologues unusually exist as lower oligomers and retain the ability to suppress aggregation of substrate proteins.
Tuberculosis
Mycobacterium tuberculosis heat-shock protein 70 impairs maturation of dendritic cells from bone marrow precursors, induces interleukin-10 production and inhibits T-cell proliferation in vitro.
Tuberculosis
Mycobacterium tuberculosis Hsp16.3 nonamers are assembled and re-assembled via trimer and hexamer intermediates.
Tuberculosis
Mycobacterium tuberculosis Rv0991c Is a Redox-Regulated Molecular Chaperone.
Tuberculosis
Natural antibodies to 65 kD mycobacterial heat shock protein in rats do not correlate with susceptibility for Mycobacterium tuberculosis induced adjuvant arthritis.
Tuberculosis
New alternative vaccine component against mycobacterium tuberculosis--heat shock protein 16.3 or its T-cell epitope.
Tuberculosis
No evidence for serological autoimmunity to islet cell heat shock proteins in insulin dependent diabetes.
Tuberculosis
Novel prophylactic and therapeutic vaccine against tuberculosis.
Tuberculosis
Novel recombinant BCG and DNA-vaccination against tuberculosis in a cynomolgus monkey model.
Tuberculosis
Novel selection for isoniazid (INH) resistance genes supports a role for NAD+-binding proteins in mycobacterial INH resistance.
Tuberculosis
Novel vaccines for the treatment of chronic HBV infection based on mycobacterial heat shock protein 70.
Tuberculosis
Optimisation of human VH domain antibodies specific to Mycobacterium tuberculosis heat shock protein (HSP16.3).
Tuberculosis
Outer membrane protein PhoE as a carrier for the exposure of foreign antigenic determinants at the bacterial cell surface.
Tuberculosis
Over-expression of gene encoding heat shock protein 70 from Mycobacterium tuberculosis and its evaluation as vaccine adjuvant.
Tuberculosis
Overexpression of DosR in Mycobacterium tuberculosis does not affect aerobic replication in vitro or in murine macrophages
Tuberculosis
Overexpression of the celA1 gene in BCG modifies surface pellicle, glucosamine content in biofilms, and affects in vivo replication.
Tuberculosis
Peptide 19 of Porphyromonas gingivalis Heat Shock Protein Is a Potent Inducer of Low-Density Lipoprotein Oxidation.
Tuberculosis
Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis.
Tuberculosis
Physiological consequences associated with overproduction of Mycobacterium tuberculosis FtsZ in mycobacterial hosts.
Tuberculosis
Porphyromonas gingivalis lipopolysaccharide antagonizes Escherichia coli lipopolysaccharide at toll-like receptor 4 in human endothelial cells.
Tuberculosis
Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.
Tuberculosis
Preferential binding with Escherichia coli hsp60 of antibodies prevalent in sera from patients with rheumatoid arthritis.
Tuberculosis
Preheat treatment for Mycobacterium tuberculosis Hsp16.3: correlation between a structural phase change at 60 degrees C and a dramatic increase in chaperone-like activity.
Tuberculosis
Preventive administration of Mycobacterium tuberculosis 10-kDa heat shock protein (hsp10) suppresses adjuvant arthritis in Lewis rats.
Tuberculosis
Probing the roles of the only universally conserved leucine residue (Leu122) in the oligomerization and chaperone-like activity of Mycobacterium tuberculosis small heat shock protein Hsp16.3.
Tuberculosis
Prophylactic, therapeutic and anti-metastatic effects of an HPV-16mE6Delta/mE7/TBhsp70Delta fusion protein vaccine in an animal model.
Tuberculosis
Protective efficacy of a DNA vaccine construct encoding the VP2 gene of infectious bursal disease and a truncated HSP70 of Mycobacterium tuberculosis in chickens.
Tuberculosis
Pulmonary necrosis resulting from DNA vaccination against tuberculosis.
Tuberculosis
Raised agalactosyl IgG and antimycobacterial humoral immunity in Takayasu's arteritis.
Tuberculosis
Raw starch microparticles have immunostimulant activity in mice vaccinated with BCG and challenged with Mycobacterium tuberculosis.
Tuberculosis
Reconstituted complexes of mycobacterial HSP70 and EBV LMP2A-derived peptides elicit peptide-specific cytotoxic T lymphocyte responses and anti-tumor immunity.
Tuberculosis
Regulation of the alpha-crystallin gene acr2 by the MprAB two-component system of Mycobacterium tuberculosis.
Tuberculosis
Requisite role for interleukin-4 in the acceleration of fatty streaks induced by heat shock protein 65 or Mycobacterium tuberculosis.
Tuberculosis
Reversible methionine sulfoxidation of Mycobacterium tuberculosis small heat shock protein Hsp16.3 and its possible role in scavenging oxidants.
Tuberculosis
Robust immunoreactivity of teenager sera against peptide 19 from Porphyromonas gingivalis HSP60.
Tuberculosis
Serodiagnosis of tuberculosis based on the analysis of the 65 kD heat shock protein of Mycobacterium tuberculosis.
Tuberculosis
Serum antibodies from patients with ankylosing spondylitis and Reiter's syndrome are reactive with HLA-B27 cells transfected with the Mycobacterium tuberculosis hsp60 gene.
Tuberculosis
Site-directed mutation on the only universally conserved residue Leu122 of small heat shock protein Hsp16.3.
Tuberculosis
Spinal fluid lymphocytes from a subgroup of multiple sclerosis patients respond to mycobacterial antigens.
Tuberculosis
Structural and functional conservation of Mycobacterium tuberculosis GroEL paralogs suggests that GroEL1 Is a chaperonin.
Tuberculosis
Superior adjuvanticity of the genetically fused D1 domain of Neisseria meningitides Ag473 lipoprotein among three Toll-like receptor ligands.
Tuberculosis
Suppression of adjuvant arthritis in rats by induction of oral tolerance to mycobacterial 65-kDa heat shock protein.
Tuberculosis
Synergistic effect of muramyl dipeptide with heat shock protein 70 from Mycobacterium tuberculosis on immune activation.
Tuberculosis
Synthesis of heat shock proteins in Thermoanaerobacterium thermosulfurigenes EM1 (Clostridium thermosulfurogenes EM1).
Tuberculosis
Synthetic peptides non-covalently bound to bacterial hsp 70 elicit peptide-specific T-cell responses in vivo.
Tuberculosis
T cell epitope expression of mycobacterial and homologous human 65-kilodalton heat shock protein peptides in short term cell lines from patients with Behçet's disease.
Tuberculosis
T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins.
Tuberculosis
T-cell recognition of mycobacterial GroES peptides in Thai leprosy patients and contacts.
Tuberculosis
TAC from Mycobacterium tuberculosis: a paradigm for stress-responsive toxin-antitoxin systems controlled by SecB-like chaperones.
Tuberculosis
Takayasu's arteritis: role of Mycobacterium tuberculosis and its 65 kDa heat shock protein.
Tuberculosis
Targeted detection of 65 kDa heat shock protein gene in endometrial biopsies for reliable diagnosis of genital tuberculosis.
Tuberculosis
Targeted induction of antigen expression within dendritic cells modulates antigen-specific immunity afforded by recombinant BCG.
Tuberculosis
TCR-like domain antibody against Mycobacterium tuberculosis (Mtb) heat shock protein antigen presented by HLA-A*11 and HLA-A*24.
Tuberculosis
Temperature-dependent subunit exchange and chaperone-like activities of Hsp16.3, a small heat shock protein from Mycobacterium tuberculosis.
Tuberculosis
Th1 polarized response induced by intramuscular DNA-HSP65 immunization is preserved in experimental atherosclerosis.
Tuberculosis
The 'tubulin-like' S1 protein of Spirochaeta is a member of the hsp65 stress protein family.
Tuberculosis
The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo.
Tuberculosis
The association of small heat shock protein Hsp16.3 with the plasma membrane of Mycobacterium tuberculosis: dissociation of oligomers is a prerequisite.
Tuberculosis
The construction of Schistosoma japonicum vaccine BCG-Sj26GST and its identification.
Tuberculosis
The heat shock response of mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis.
Tuberculosis
The humoral response in TCR alpha-/- mice. Can gammadelta-T cells support the humoral immune response?
Tuberculosis
The immune response to mycobacterial 70-kDa heat shock proteins frequently involves autoreactive T cells and is quantitatively disregulated in multiple sclerosis.
Tuberculosis
The impact of different mutations at arginine141 on the structure, subunit exchange dynamics and chaperone activity of Hsp16.3.
Tuberculosis
The impact of DR3 microvariation on peptide binding: the combinations of specific DR beta residues critical to binding differ for different peptides.
Tuberculosis
The mycobacterial GroEL stress protein: a common target of T-cell recognition in infection and autoimmunity.
Tuberculosis
The Mycobacterium tuberculosis 65-kilodalton antigen is a heat shock protein which corresponds to common antigen and to the Escherichia coli GroEL protein.
Tuberculosis
The Mycobacterium tuberculosis small heat shock protein Hsp16.3 exposes hydrophobic surfaces at mild conditions: conformational flexibility and molecular chaperone activity.
Tuberculosis
The potent bone-resorbing mediator of Actinobacillus actinomycetemcomitans is homologous to the molecular chaperone GroEL.
Tuberculosis
The recombinant 65-kD heat shock protein of Mycobacterium bovis Bacillus Calmette-Guerin/M. tuberculosis is a target molecule for CD4+ cytotoxic T lymphocytes that lyse human monocytes.
Tuberculosis
Therapeutic efficacy of a tuberculosis DNA vaccine encoding heat shock protein 65 of Mycobacterium tuberculosis and the human interleukin 2 fusion gene.
Tuberculosis
Treatment of adjuvant arthritis with granulocyte-colony stimulating factor and peptide derived from heat shock protein 65.
Tuberculosis
Use of restriction enzyme analysis of amplified DNA coding for the hsp65 gene and polymerase chain reaction with universal primer for rapid differentiation of mycobacterium species in the clinical laboratory.
Tuberculosis
Vaccination against tuberculosis by DNA injection.
Tuberculosis
Vaccine adjuvant: it makes the difference.
Tuberculosis
VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever.
Tuberculosis
Virulence, immunogenicity, and protective efficacy of two recombinant Mycobacterium bovis bacillus Calmette-Guérin strains expressing the antigen ESAT-6 from Mycobacterium tuberculosis.
Tuberculosis
[Amplification of 2 different gene segments of Mycobacterium tuberculosis and its usefulness in the diagnosis of tuberculosis]
Tuberculosis
[Anti-tuberculosis immunity by cytotoxic T cells * granulysin and the development of novel vaccines (HSP-65 DNA+IL-12 DNA)]
Tuberculosis
[Cloning and prokaryotic expression of heat shock protein 70 gene of Mycobacterium tuberculosis]
Tuberculosis
[Construction of a secreting prokaryotic shuttle expressing plasmid pBCG-sP-HSP65 and its expression in Mycobacterial smegmatis]
Tuberculosis
[Construction of fusion gene vaccine of WT1 multi-epitope fused with stimulating epitope of mycobacterium tuberculosis heat shock protein 70 and its expression and immunogenicity].
Tuberculosis
[Construction of recombinant Mycobacterium smegmatis expressing ESAT-6 and its effects on macrophages]
Tuberculosis
[Construction of replication-deficient recombinant adenoviral vector carrying HBsAg and HSP70 chimeric gene and its expression in vitro]
Tuberculosis
[Construction of the eukaryotic coexpression vector containing Mycobacterium tuberculosis heat shock protein 70 and green fluorescent protein.]
Tuberculosis
[Heat-shock protein enhances immunogenicity of E7 oncoprotein of human papillomavirus included in chimeric construction (E7 HPV-HSP70)].
Tuberculosis
[Histological and immunohistochemical structure of pulmonary tuberculotic granulomas in untreated cases and cases treated with antitubercular drugs]
Tuberculosis
[Immune adjuvant effect of TB.HSP70 to its accompanying cytotoxic T lymphocytes epitope elicits HBV specific immune response]
Tuberculosis
[Immunocontraceptive effect of DNA vaccines of Lagurus lagurus zona pellucida 3 fusioned with C-terminal of HSP70.]
Tuberculosis
[Immunogenic Mycobacterium tuberculosis heat shock protein in tuberculosis]
Tuberculosis
[Improved efficacy of P277 fused to heat shock protein 65 of Mycobacterium tuberculosis against diabetes in nonobese diabetic mice]
Tuberculosis
[Intranasal vaccination with mycobacterial 65-kD heat-shock protein can prevent insulitis and diabetes in non-obese diabetic mice].
Tuberculosis
[Intratumor injection of recombinant attenuated salmonella carrying Mycobacterium tuberculosis heat shock protein 70 and herpes simplex virus thymidine kinase genes to suppress murine melanoma growth].
Tuberculosis
[Novel vaccines against M. tuberculosis]
Tuberculosis
[Participation of gamma/delta-T cells in the protection against mycobacterial infection]
Tuberculosis
[Participation of heat shock proteins in modulation of NF-?B transcription factor activation during bacterial infections].
Tuberculosis
[Prokaryotic expression and function detection of Mycobacterium tuberculosis Hsp16.3].
Tuberculosis
[Proteomic analysis of U937 cells expressing Mycobacterium tuberculosis heat shock protein 16.3].
Tuberculosis
[Rapid detection and identification of mycobacteria by the PCR assay based on the co-amplification of the gene IS6110 and groEL]
Tuberculosis
[Role of molecular adjuvants TBhsp and MT in the preparation of monoclonal antibody against phosphatase of regenerating liver-3].
Tuberculosis
[Secretion expression of Mt. heat shock protein 70 in Pichia pastoris and identification of the protein]
Tuberculosis
[Study of HSP70 gene upstream regulation element on expression efficiency of GST gene in M. smegmatis]
Tuberculosis
[The development of novel vaccines against tuberculosis]
Tuberculosis
[The immunological responses induced by Mycobacterium tuberculosis heat shock protein 16.3 and its synthetic peptide in mice]
Tuberculosis, Bovine
Heat shock protein 70 subunit vaccination against bovine paratuberculosis does not interfere with current immunodiagnostic assays for bovine tuberculosis.
Tuberculosis, Meningeal
Detection of 65 kD heat shock protein in cerebrospinal fluid of tuberculous meningitis patients.
Tuberculosis, Meningeal
Polymerase chain reaction, with sequencing, as a diagnostic tool in culture---negative bacterial meningitis.
Tuberculosis, Pulmonary
Polymorphism in heat-shock protein 70-1 (HSP70-1) gene promoter region and susceptibility to tuberculoid leprosy and pulmonary tuberculosis in Asian Indians.
Tuberous Sclerosis
MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Tuberous Sclerosis
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity.
Tuberous Sclerosis
The Role of Heat Shock Protein-90 in the Pathogenesis of Birt-Hogg-Dubé and Tuberous Sclerosis Complex Syndromes.
Tuberous Sclerosis
Tuberous sclerosis complex protein 1 expression is affected by VHL Gene alterations and HIF-1? production in sporadic clear-cell renal cell carcinoma.
Tularemia
B-cell epitopes in GroEL of Francisella tularensis.
type i protein arginine methyltransferase deficiency
PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability.
Typhoid Fever
Effect of adjuvants on immune response and protective immunity elicited by recombinant Hsp60 (GroEL) of Salmonella typhi against S. typhi infection.
Typhoid Fever
Immunogenic epitopes of Salmonella typhi GroEL heat shock protein reactive with both monoclonal antibody and patients sera.
Typhus, Endemic Flea-Borne
Molecular epidemic survey on co-prevalence of scrub typhus and marine typhus in Yuxi city, Yunnan province of China.
Typhus, Epidemic Louse-Borne
Molecular cloning and sequence analysis of the Sta58 major antigen gene of Rickettsia tsutsugamushi: sequence homology and antigenic comparison of Sta58 to the 60-kilodalton family of stress proteins.
Typhus, Epidemic Louse-Borne
Molecular detection and groEL typing of Rickettsia aeschlimannii in Sardinian ticks.
Typhus, Epidemic Louse-Borne
Molecular epidemic survey on co-prevalence of scrub typhus and marine typhus in Yuxi city, Yunnan province of China.
Uremia
Obstruction of proximal tubules initiates cytoresistance against hypoxic damage.
Uremia
Resveratrol Reduces Kidney Injury in a Rat Model of Uremia and is Associated with Increased Expression of Heat Shock Protein 70 (Hsp70).
Ureteral Obstruction
Activation of AMP-activated protein kinase inhibits ER stress and renal fibrosis.
Ureteral Obstruction
Effect of laminarin on the expression of GRP78 and GRP94 in rat after unilateral ureteral obstruction.
Ureteral Obstruction
Heat shock protein 90 inhibitor attenuates renal fibrosis through degradation of transforming growth factor-? type II receptor.
Ureteral Obstruction
Increased heat shock protein-70 in unilateral ureteral obstruction in rats.
Ureteral Obstruction
The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO).
Ureteral Obstruction
Wt-1 Expression Linked to Nitric Oxide Availability during Neonatal Obstructive Nephropathy.
Urethral Obstruction
Increased expression of heat shock protein 20 and decreased contractile stress in obstructed rat bladder.
Urethritis
Antibodies to Chlamydia trachomatis heat-shock protein 60 kDa and detection of Mycoplasma genitalium and ureaplasma urealyticum are associated independently with chronic nongonococcal urethritis.
Urethritis
Association of antibodies to Chlamydia trachomatis heat-shock protein 60 kD with chronic nongonococcal urethritis.
Urinary Bladder Neck Obstruction
Increased expression of heat shock protein 20 and decreased contractile stress in obstructed rat bladder.
Urinary Bladder Neoplasms
17-Allylamino-17-demethoxygeldanamycin induces downregulation of critical Hsp90 protein clients and results in cell cycle arrest and apoptosis of human urinary bladder cancer cells.
Urinary Bladder Neoplasms
17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.
Urinary Bladder Neoplasms
Clinical significance of heat shock protein-70 expression in bladder cancer.
Urinary Bladder Neoplasms
Clinical, prognostic, and therapeutic significance of heat shock protein 27 in bladder cancer.
Urinary Bladder Neoplasms
Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.
Urinary Bladder Neoplasms
Discovering Therapeutic Protein Targets for Bladder Cancer Using Proteomic Data Analysis
Urinary Bladder Neoplasms
Dual targeting of heat shock proteins 90 and 70 promotes cell death and enhances the anticancer effect of chemotherapeutic agents in bladder cancer.
Urinary Bladder Neoplasms
Dysregulated genes targeted by microRNAs and metabolic pathways in bladder cancer revealed by bioinformatics methods.
Urinary Bladder Neoplasms
Enhanced sensitivity to mitomycin C by abating heat shock protein 70 expression in human bladder cancer cell line of BIU-87.
Urinary Bladder Neoplasms
FGFR3 translocations in bladder cancer: differential sensitivity to HSP90 inhibition based on drug metabolism.
Urinary Bladder Neoplasms
Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin.
Urinary Bladder Neoplasms
Heat shock protein expression in testis and bladder cancer cell lines exhibiting differential sensitivity to heat.
Urinary Bladder Neoplasms
Heat shock protein expression independently predicts survival outcome in schistosomiasis-associated urinary bladder cancer.
Urinary Bladder Neoplasms
Heat shock protein-90, IL-6 and IL-10 in bladder cancer.
Urinary Bladder Neoplasms
Heat shock proteins 60 and 70 are associated with long-term outcome of T1-stage high-grade urothelial tumors of the bladder treated with intravesical Bacillus Calmette-Guérin immunotherapy.
Urinary Bladder Neoplasms
Heat-shock protein 70-2 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumour progression and promotes migration and invasion.
Urinary Bladder Neoplasms
High expression of heat shock protein 105 predicts a favorable prognosis for patients with urinary bladder cancer treated with radical cystectomy.
Urinary Bladder Neoplasms
HSP60 may predict good pathological response to neoadjuvant chemoradiotherapy in bladder cancer.
Urinary Bladder Neoplasms
HSP90 expression: a new predictive factor for BCG response in stage Ta-T1 grade 3 bladder tumours.
Urinary Bladder Neoplasms
Humoral response against heat shock proteins and other mycobacterial antigens after intravesical treatment with bacille Calmette-Guérin (BCG) in patients with superficial bladder cancer.
Urinary Bladder Neoplasms
Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model.
Urinary Bladder Neoplasms
Immunohistochemical detection of the 150-kDa oxygen-regulated protein in bladder cancer.
Urinary Bladder Neoplasms
Inhibition of inducible heat shock protein-70 (hsp72) enhances bortezomib-induced cell death in human bladder cancer cells.
Urinary Bladder Neoplasms
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer.
Urinary Bladder Neoplasms
Low dose geldanamycin inhibits hepatocyte growth factor and hypoxia-stimulated invasion of cancer cells.
Urinary Bladder Neoplasms
Low-dose Hsp90 inhibitors tumor-selectively sensitize bladder cancer cells to chemoradiotherapy.
Urinary Bladder Neoplasms
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.
Urinary Bladder Neoplasms
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity.
Urinary Bladder Neoplasms
p63? protein up-regulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion.
Urinary Bladder Neoplasms
Potential role of Hsp90 inhibitors in overcoming cisplatin resistance of bladder cancer-initiating cells.
Urinary Bladder Neoplasms
Proteomic analysis of proteome and histone post-translational modifications in heat shock protein 90 inhibition-mediated bladder cancer therapeutics.
Urinary Bladder Neoplasms
Small interfering RNA targeting heat shock protein 70 enhances chemosensitivity in human bladder cancer cells.
Urinary Bladder Neoplasms
Synergistic Antitumor Effects of Combined Treatment with HSP90 Inhibitor and PI3K/mTOR Dual Inhibitor in Cisplatin-Resistant Human Bladder Cancer Cells.
Urinary Bladder Neoplasms
Targeted inhibition of heat shock protein 90 disrupts multiple oncogenic signaling pathways, thus inducing cell cycle arrest and programmed cell death in human urinary bladder cancer cell lines.
Urinary Bladder Neoplasms
Targeting Hsp90 in urothelial carcinoma.
Urinary Bladder Neoplasms
The effect of heat shock protein 90 inhibitors on histone 4 lysine 20 methylation in bladder cancer.
Urinary Bladder Neoplasms
[The heat shock protein 70 antisense oligomers enhance the sensitivity of bladder cancer cell EJ to mitomycin C]
Urinary Tract Infections
Heat shock protein 72 (HSPA1B) gene polymorphism and Toll-like receptor (TLR) 4 mutation are associated with increased risk of urinary tract infection in children.
Urinary Tract Infections
The curli biogenesis genes expression level is unassociated with Enterobacter cloacae hsp60 clusters and PFGE genotypes.
Urinary Tract Infections
Urine heat shock protein 70 levels as a marker of urinary tract infection in children.
Urologic Neoplasms
Heat shock proteins: their role in urological tumors.
Urologic Neoplasms
Mechanisms of disease: the role of heat-shock protein 90 in genitourinary malignancy.
Urticaria
Elevated circulating heat shock protein 70 and its antibody concentrations in chronic spontaneous urticaria.
Uterine Cervical Neoplasms
A novel MtHSP70-FPR1 fusion protein enhances cytotoxic T lymphocyte responses to cervical cancer cells by activating human monocyte-derived dendritic cells via the p38 MAPK signaling pathway.
Uterine Cervical Neoplasms
Are IgG antibodies to heat shock proteins HSP27 and HSP60 useful markers in endometrial cancer and cervical cancer?
Uterine Cervical Neoplasms
Assessment of hypoxia inducible factor levels in cancer cell lines upon hypoxic induction using a novel reporter construct.
Uterine Cervical Neoplasms
Boosting the effects of hyperthermia-based anticancer treatments by HSP90 inhibition.
Uterine Cervical Neoplasms
Bortezomib Targets the Caspase-Like Proteasome Activity in Cervical Cancer Cells, Triggering Apoptosis That Can be Enhanced by Nelfinavir.
Uterine Cervical Neoplasms
CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer.
Uterine Cervical Neoplasms
Correction: Soluble B and T Lymphocyte Attenuator Possesses Antitumor Effects and Facilitates Heat Shock Protein 70 Vaccine-Triggered Antitumor Immunity against a Murine TC-1 Cervical Cancer Model In Vivo.
Uterine Cervical Neoplasms
Diagnostic value of heat shock protein 90? and squamous cell carcinoma antigen in detection of cervical cancer.
Uterine Cervical Neoplasms
E6^E7, a novel splice isoform protein of human papillomavirus 16, stabilizes viral E6 and E7 oncoproteins via HSP90 and GRP78.
Uterine Cervical Neoplasms
Effect of a heat shock protein 90-specific inhibitor on the proliferation and apoptosis induced by VEGF-C in cervical cancer cells.
Uterine Cervical Neoplasms
Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer.
Uterine Cervical Neoplasms
Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro.
Uterine Cervical Neoplasms
Enhancement of Radiation Effectiveness in Cervical Cancer Cells by Combining Ionizing Radiation with Hyperthermia and Molecular Targeting Agents.
Uterine Cervical Neoplasms
Evaluation of short- and long-term efficacy of chemoradiotherapy for advanced cervical cancer using HSP70 protein combined with multimodal MRI.
Uterine Cervical Neoplasms
Expression of heat shock protein 60 kDa is upregulated in cervical cancer.
Uterine Cervical Neoplasms
Germ cell-specific heat shock protein 70-2 is expressed in cervical carcinoma and is involved in the growth, migration, and invasion of cervical cells.
Uterine Cervical Neoplasms
Glucose-Related Protein 78 Expression and Its Effects on Cisplatin-Resistance in Cervical Cancer.
Uterine Cervical Neoplasms
Heat shock protein 90 inhibitor mycoepoxydiene modulates kinase signaling in cervical cancer cells and inhibits in-vivo tumor growth.
Uterine Cervical Neoplasms
Hsp90 Inhibitor SNX-2112 Enhances TRAIL-Induced Apoptosis of Human Cervical Cancer Cells via the ROS-Mediated JNK-p53-Autophagy-DR5 Pathway.
Uterine Cervical Neoplasms
Human papillomavirus E6: Host cell receptor, GRP78, binding site prediction.
Uterine Cervical Neoplasms
LINC00294 induced by GRP78 promotes cervical cancer development by promoting cell cycle transition.
Uterine Cervical Neoplasms
MicroRNA-361-Mediated Inhibition of HSP90 Expression and EMT in Cervical Cancer Is Counteracted by Oncogenic lncRNA NEAT1.
Uterine Cervical Neoplasms
MicroRNA216b mediated downregulation of HSP27/STAT3/AKT signaling is critically involved in lambertianic acid induced apoptosis in human cervical cancers.
Uterine Cervical Neoplasms
MiR-181a Inhibits Cervical Cancer Development Via Downregulating GRP78.
Uterine Cervical Neoplasms
MTBHsp70-exFPR1-pulsed Dendritic Cells Enhance the Immune Response against Cervical Cancer.
Uterine Cervical Neoplasms
Novel immunohistochemical monoclonal antibody against human glucose-regulated protein 78.
Uterine Cervical Neoplasms
Proteomic analysis of cancer tissues: shedding light on carcinogenesis and possible biomarkers.
Uterine Cervical Neoplasms
Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer.
Uterine Cervical Neoplasms
Recombinant heat shock protein 27 (HSP27/HSPB1) protects against cadmium-induced oxidative stress and toxicity in human cervical cancer cells.
Uterine Cervical Neoplasms
Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells.
Uterine Cervical Neoplasms
Serum antibody response to the heat shock protein 60 of Chlamydia trachomatis in women with developing cervical cancer.
Uterine Cervical Neoplasms
Soluble B and T lymphocyte attenuator possesses antitumor effects and facilitates heat shock protein 70 vaccine-triggered antitumor immunity against a murine TC-1 cervical cancer model in vivo.
Uterine Cervical Neoplasms
Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cells.
Uterine Cervical Neoplasms
Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures.
Uterine Cervical Neoplasms
Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts.
Uterine Cervical Neoplasms
The effects of irradiation on the expression of a tumour rejection antigen (heat shock protein gp96) in human cervical cancer.
Uterine Cervical Neoplasms
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer.
Uterine Cervical Neoplasms
Ultrasound irradiation inhibits proliferation of cervical cancer cells by initiating endoplasmic reticulum stress-mediated apoptosis and triggering phosphorylation of JNK.
Uterine Cervical Neoplasms
[Expressions of heat shock protein in cervical cancer and precancerosis].
Uterine Cervical Neoplasms
[Therapeutic effects of B and T lymphocyte attenuator extracellular domain and heat shock protein 70 antigen peptide on cervical cancer in mouse model.]
Uterine Neoplasms
Paclitaxel inhibits expression of heat shock protein 27 in ovarian and uterine cancer cells.
Uveitis
Administration of Mycobacterium leprae rHsp65 aggravates experimental autoimmune uveitis in mice.
Uveitis
Association between heat shock protein 70/Hom genetic polymorphisms and uveitis in patients with sarcoidosis.
Uveitis
Circulating antibodies to inducible heat shock protein 70 in patients with uveitis.
Uveitis
Common antigenicity between Yersinia enterocolitica-derived heat-shock protein and the retina, and its role in uveitis.
Uveitis
Cytokine, C-Reactive Protein, and Heat Shock Protein mRNA Expression Levels in Patients with Active Behçet's Uveitis.
Uveitis
Diagnostic yield of heat shock protein 70 (HSP-70) and anti-HSP-70 in Behcet-induced uveitis.
Uveitis
Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis.
Uveitis
Experimental mucosal induction of uveitis with the 60-kDa heat shock protein-derived peptide 336-351.
Uveitis
High levels of IgG class antibodies to recombinant HSP60 kDa of Yersinia enterocolitica in sera of patients with uveitis.
Uveitis
HSP-derived peptides inducing uveitis and IgG and IgA antibodies.
Uveitis
Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis.
Uveitis
Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor.
Uveitis
Prevention of mucosally induced uveitis with a HSP60-derived peptide linked to cholera toxin B subunit.
Uveitis
Small heat shock protein ?A-crystallin prevents photoreceptor degeneration in experimental autoimmune uveitis.
Uveitis, Anterior
Chlamydial antibodies in patients with previous acute anterior uveitis.
Vaccinia
CD8+ T cells, NK cells and IFN-gamma are important for control of tumor with downregulated MHC class I expression by DNA vaccination.
Vaccinia
Heat shock protein and heat shock factor 1 expression and localization in vaccinia virus infected human monocyte derived macrophages.
Vaccinia
Highly persistent and effective prime/boost regimens against tuberculosis that use a multivalent modified vaccine virus Ankara-based tuberculosis vaccine with interleukin-15 as a molecular adjuvant.
Vaccinia
Human Hsp60: bacterial expression, purification, development of monoclonal antibodies and a sandwich ELISA for quantitation.
Vaccinia
Humoral immune response of BALB/c mice to a vaccinia virus recombinant expressing Brucella abortus GroEL does not correlate with protection against a B. abortus challenge.
Vaccinia
Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein.
Vaccinia
Modulation of experimental autoimmunity: treatment of adjuvant arthritis by immunization with a recombinant vaccinia virus.
Vaccinia
Molecular chaperone Hsp90 is important for vaccinia virus growth in cells.
Vaccinia
siRNA screen of early poxvirus genes identifies the AAA+ ATPase D5 as the virus genome-uncoating factor.
Vaccinia
Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis.
Vaccinia
VRK3-mediated nuclear localization of HSP70 prevents glutamate excitotoxicity-induced apoptosis and A? accumulation via enhancement of ERK phosphatase VHR activity.
Vagus Nerve Injuries
Induction of the 27-kDa heat shock protein (Hsp27) in the rat medulla oblongata after vagus nerve injury.
Varicocele
Effect of varicocelectomy treatment on spermatogenesis and apoptosis via the induction of heat shock protein 70 in varicocele?induced rats.
Varicocele
Heat shock protein and heat shock factor expression in sperm: relation to oligozoospermia and varicocele.
Varicocele
Is thioredoxin reductase involved in the defense against DNA fragmentation in varicocele?
Varicocele
Single nucleotide polymorphisms of the heat shock protein 90 gene in varicocele-associated infertility.
Varicocele
Testosterone amplifies HSP70-2a, HSP90 and PCNA expression in experimental varicocele condition: Implication for DNA fragmentation.
Varicocele
Testosterone and vitamin E administration up-regulated varicocele-reduced Hsp70-2 protein expression and ameliorated biochemical alterations.
Vascular Calcification
Effect of endoplasmic reticulum stress-induced apoptosis in the role of periodontitis on vascular calcification in a rat model.
Vascular Diseases
Effect of combined heat, ozonation and ultraviolet irradiation (VasoCare) on heat shock protein expression by peripheral blood leukocyte populations.
Vascular Diseases
Elevated levels of circulating heat shock protein 70 (Hsp70) in peripheral and renal vascular disease.
Vascular Diseases
GRP78 signaling hub a receptor for targeted tumor therapy.
Vascular Diseases
Heat shock protein 27: its potential role in vascular disease.
Vascular Diseases
Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes.
Vascular Diseases
Heat shock protein antibody titers are reduced by statin therapy in dyslipidemic subjects: a pilot study.
Vascular Diseases
Heat shock proteins in vascular disease--a review.
Vascular Diseases
HSP47 in lung fibroblasts is a predictor of survival in fibrotic nonspecific interstitial pneumonia.
Vascular Diseases
HSP60 and anti-HSP60 antibodies in vasculitis: they are two of a kind.
Vascular Diseases
Human heat shock protein 60 stimulates vascular smooth muscle cell proliferation through Toll-like receptors 2 and 4.
Vascular Diseases
Improved Metabolic Control in Diabetes, HSP60, and Proinflammatory Mediators.
Vascular Diseases
Modulation of endothelial cell damages by anti-Hsp60 autoantibodies in systemic autoimmune diseases.
Vascular Diseases
Small molecular weight heat shock-related protein, HSP20, exhibits an anti-platelet activity by inhibiting receptor-mediated calcium influx.
Vascular System Injuries
Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat.
Vascular System Injuries
Mitochondrial Heat Shock Protein-90 Modulates Vascular Smooth Muscle Cell Survival and the Vascular Injury Response in Vivo.
Vasculitis
HSP60 and anti-HSP60 antibodies in vasculitis: they are two of a kind.
Vasculitis
Mitochondrial heat shock protein (HSP) 70 synergizes with HSP60 in transducing endothelial cell apoptosis induced by anti-HSP60 autoantibody.
Vasospasm, Intracranial
Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage.
Vasospasm, Intracranial
Treatment of experimental cerebral vasospasm by protein transduction of heme oxygenase 1 (HO-1) conjugated to a residue of 11 arginines.
Vector Borne Diseases
GRP78 Is an Important Host Factor for Japanese Encephalitis Virus Entry and Replication in Mammalian Cells.
Venous Thromboembolism
Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.
Ventricular Dysfunction
Regulation of A-Kinase-Anchoring Protein 12 by Heat Shock Protein A12B to Prevent Ventricular Dysfunction Following Acute Myocardial Infarction in Diabetic Rats.
Vertigo
HSP70 antibodies in 80 patients with "clinically certain" Meniere's disease.
Vesicular Stomatitis
Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses.
Vesicular Stomatitis
Antiviral effect of short hyperthermic treatment at specific stages of vesicular stomatitis virus replication cycle.
Vesicular Stomatitis
Effect of combined alpha IFN and prostaglandin A1 treatment on vesicular stomatitis virus replication and heat shock protein synthesis in epithelial cells.
Vesicular Stomatitis
Endoplasmic reticulum chaperone gp96 is essential for infection with vesicular stomatitis virus.
Vesicular Stomatitis
Heat Shock Protein 70 Enhances Mucosal Immunity against Human Norovirus When Coexpressed from a Vesicular Stomatitis Virus Vector.
Vesicular Stomatitis
HSP90 Chaperoning in Addition to Phosphoprotein Required for Folding but Not for Supporting Enzymatic Activities of Measles and Nipah Virus L Polymerases.
Vesicular Stomatitis
Inhibition of poliovirus replication by prostaglandins A and J in human cells.
Vibrio Infections
Evidence for disruption of Na(+)-K(+)-ATPase and hsp70 during vibriosis of sea bream, Sparus (=Rhabdosargus) sarba Forsskål.
Vibrio Infections
Reactive oxygen species generated by a heat shock protein (Hsp) inducing product contributes to Hsp70 production and Hsp70-mediated protective immunity in Artemia franciscana against pathogenic vibrios.
Viremia
Inhibition of Heat Shock Protein 90 Prevents HIV Rebound.
Virus Diseases
A cellular protein related to heat-shock protein 90 accumulates during herpes simplex virus infection and is overexpressed in transformed cells.
Virus Diseases
A molecular chaperone glucose-regulated protein 94 blocks apoptosis induced by virus infection.
Virus Diseases
A plant reovirus hijacks endoplasmic reticulum-associated degradation machinery to promote efficient viral transmission by its planthopper vector under high temperature conditions.
Virus Diseases
Association of heat-shock protein 70 with lipid rafts is required for Japanese encephalitis virus infection in Huh7 cells.
Virus Diseases
Atherosclerosis and connective tissue diseases.
Virus Diseases
Cellular chaperones and folding enzymes are vital contributors to membrane bound replication and movement complexes during plant RNA virus infection.
Virus Diseases
Cellular DNAJA3, a Novel VP1-Interacting Protein, Inhibits Foot-and-Mouth Disease Virus Replication by Inducing Lysosomal Degradation of VP1 and Attenuating Its Antagonistic Role in the Beta Interferon Signaling Pathway.
Virus Diseases
Chaperone-mediated in vitro assembly of Polyomavirus capsids.
Virus Diseases
Chicken Heat Shock Protein 70 Is an Essential Host Protein for Infectious Bursal Disease Virus Infection In Vitro.
Virus Diseases
Cloning and expression analysis of heat shock cognate 70 gene promoter in tiger shrimp (Penaeus monodon).
Virus Diseases
COVID-19 and Cell Stress.
Virus Diseases
Cytoskeletal proteins bound to heat-shock protein 70 may elicit resistance to simian immunodeficiency virus infection of CD4(+) T cells.
Virus Diseases
Dengue virus infection induces GRP78 which acts to chaperone viral antigen production.
Virus Diseases
Development and application of Hsp90 inhibitors.
Virus Diseases
Differential expression of three Paralichthys olivaceus Hsp40 genes in responses to virus infection and heat shock.
Virus Diseases
Diversity in heat shock protein families: functional implications in virus infection with a comprehensive insight of their role in the HIV-1 life cycle.
Virus Diseases
Effects of heat treatment on metabolism of tobacco plants infected with Potato virus Y.
Virus Diseases
Endogenous activated siRNAs in virus-infected Brassicaceae crops show a common host gene silencing pattern affecting photosynthesis and stress-response.
Virus Diseases
Evidence for an association between heat shock protein 70 and the respiratory syncytial virus polymerase complex within lipid-raft membranes during virus infection.
Virus Diseases
Functional role of Hsp60 as a positive regulator of human viral infection progression.
Virus Diseases
GRP78 / BiP / HSPA5 / Dna K is a universal therapeutic target for human disease.
Virus Diseases
Harnessing an RNA-mediated chaperone for the assembly of influenza hemagglutinin in an immunologically relevant conformation.
Virus Diseases
HBx protein of hepatitis B virus (HBV) can form complex with mitochondrial HSP60 and HSP70.
Virus Diseases
Heat shock protein 19.9 (Hsp19.9) from Bombyx mori is involved in host protection against viral infection.
Virus Diseases
Heat Shock Protein 27 Mediated Signaling in Viral Infection.
Virus Diseases
Heat shock protein 70 as a supplementary receptor facilitates enterovirus 71 infections in vitro.
Virus Diseases
Heat shock protein 70 is necessary for Rice stripe virus infection in plants.
Virus Diseases
Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells.
Virus Diseases
Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions.
Virus Diseases
Heat shock proteins stimulate APOBEC-3-mediated cytidine deamination in the hepatitis B virus.
Virus Diseases
Heat-shock protein 90? is involved in maintaining the stability of VP16 and VP16-mediated transactivation of ? genes from herpes simplex virus-1.
Virus Diseases
Hepatitis B virus enhances cisplatin-induced hepatotoxicity via a mechanism involving suppression of glucose-regulated protein of 78 Kda.
Virus Diseases
Hsc70 regulates the IRES activity and serves as an antiviral target of enterovirus A71 infection.
Virus Diseases
Hsp70 negatively controls rotavirus protein bioavailability in caco-2 cells infected by the rotavirus RF strain.
Virus Diseases
Hsp90 inhibitor AT-533 blocks HSV-1 nuclear egress and assembly.
Virus Diseases
HSP90: a promising broad-spectrum antiviral drug target.
Virus Diseases
Human Hsp60: bacterial expression, purification, development of monoclonal antibodies and a sandwich ELISA for quantitation.
Virus Diseases
Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis.
Virus Diseases
In vivo and in vitro association of hsc70 with polyomavirus capsid proteins.
Virus Diseases
Increased expression of Hsp70 and co-localization with nuclear protein in cells infected with the Hantaan virus.
Virus Diseases
Inducible transgenic tobacco system to study the mechanisms underlying chlorosis mediated by the silencing of chloroplast heat shock protein 90.
Virus Diseases
Induction of pro-viral grass carp Ctenopharyngodon idella Hsp70 instead of Hsc70 during infection of grass carp reovirus.
Virus Diseases
Influence of cytoplasmic heat shock protein 70 on viral infection of Nicotiana benthamiana.
Virus Diseases
Influenza Virus Infection Induces the Nuclear Relocalization of the Hsp90 Co-Chaperone p23 and Inhibits the Glucocorticoid Receptor Response.
Virus Diseases
Influenza virus inhibits cleavage of the HSP70 pre-mRNAs at the polyadenylation site.
Virus Diseases
Inhibition of heat shock protein 90 suppresses Bombyx mori nucleopolyhedrovirus replication in B. mori.
Virus Diseases
Inhibition of infectious bursal disease virus infection by artificial miRNAs targeting the chicken heat shock protein 90.
Virus Diseases
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits.
Virus Diseases
Mechanism and Complex Roles of HSC70 in Viral Infections.
Virus Diseases
Molecular chaperone Hsp90 is important for vaccinia virus growth in cells.
Virus Diseases
Mortalin restricts porcine epidemic diarrhea virus entry by downregulating clathrin-mediated endocytosis.
Virus Diseases
Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain.
Virus Diseases
Non-lethal heat shock increased hsp70 and immune protein transcripts but not Vibrio tolerance in the white-leg shrimp.
Virus Diseases
Oncolytic Newcastle disease virus induces autophagy-dependent immunogenic cell death in lung cancer cells.
Virus Diseases
Pepino mosaic virus capsid protein interacts with a tomato heat shock protein cognate 70.
Virus Diseases
Pesticide and pathogen: heat shock protein expression and acetylcholinesterase inhibition in juvenile Chinook salmon in response to multiple stressors.
Virus Diseases
Protein analysis of purified respiratory syncytial virus particles reveals an important role for heat shock protein 90 in virus particle assembly.
Virus Diseases
Recombinant heat shock protein 78 enhances enterovirus 71 propagation in Vero cells and is induced in SK-N-SH cells during the infection.
Virus Diseases
Recruitment of the host plant heat shock protein 70 by Tomato yellow leaf curl virus coat protein is required for virus infection.
Virus Diseases
RNA interference mediated silencing of Hsp60 gene in human monocytic myeloma cell line U937 revealed decreased dengue virus multiplication.
Virus Diseases
Role of Heat Shock Proteins (HSP70 and HSP90) in Viral Infection.
Virus Diseases
Severity of viral infection is promoted by hyperthermic pretreatment.
Virus Diseases
T cells against a bacterial heat shock protein recognize stressed macrophages.
Virus Diseases
The 90-kDa heat shock protein protects mammalian cells from thermal stress but not from viral infection.
Virus Diseases
The antiviral role of heat shock protein 27 against red spotted grouper nervous necrosis virus infection in sea perch.
Virus Diseases
The Host Heat Shock Protein MRJ/DNAJB6 Modulates Virus Infection.
Virus Diseases
The interaction of white spot syndrome virus envelope protein VP28 with shrimp Hsc70 is specific and ATP-dependent.
Virus Diseases
The outcome of poliovirus infections in K562 cells is cytolytic rather than persistent after hemin-induced differentiation.
Virus Diseases
The Peptide-Binding and ATPase Domains of Recombinant hsc70 Are Required To Interact with Rotavirus and Reduce Its Infectivity.
Virus Diseases
Tomato plant cell death induced by inhibition of HSP90 is alleviated by Tomato yellow leaf curl virus infection.
Virus Diseases
Transcriptional activation of endoplasmic reticulum chaperone GRP78 by HCMV IE1-72 protein.
Virus Diseases
Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA.
Virus Diseases
Viral infection and serum antibodies to heat shock protein 70 in the acute phase of Ménière's disease.
Virus Diseases
Virus-heat shock protein interaction and a novel axis for innate antiviral immunity.
Virus Diseases
Virus-induced gene silencing reveals signal transduction components required for the Pvr9-mediated hypersensitive response in Nicotiana benthamiana.
Virus Diseases
[Complex of recombinant heat shock protein with lipopolysaccharide induces rapid protection of mice against Salmonella typhimurium and avirulent for humans avian influenza virus H5N2]
Vision Disorders
A rat retinal damage model predicts for potential clinical visual disturbances induced by Hsp90 inhibitors.
Vision Disorders
Retinal toxicity induced by small-molecule Hsp90 inhibitors in beagle dogs.
Vitamin B 6 Deficiency
Effects of Pyridoxine Deficiency on Hippocampal Function and Its Possible Association with V-Type Proton ATPase Subunit B2 and Heat Shock Cognate Protein 70.
Vitamin D Deficiency
Effects of exogenous vitamin D on endoplasmic reticulum stress-related factors in the vitamin D deficiency rats with cerebral ischemia.
Vitiligo
A central role for inducible heat-shock protein 70 in autoimmune vitiligo.
Vitiligo
Autoantigens in Vitiligo Identified by the Serological Selection of a Phage-Displayed Melanocyte cDNA Expression Library.
Vitiligo
Enhanced bleaching treatment: opportunities for immune-assisted melanocyte suicide in vitiligo.
Vitiligo
Heat Shock Protein-70 Expression in Vitiligo and its Relation to the Disease Activity.
Vitiligo
Immunohistochemical expression of heat shock protein 70 in vitiligo.
Vitiligo
The multi-target mechanism of Cyclosporin A in the treatment of vitiligo based on network pharmacology.
Vitiligo
Treatment with Modified Heat Shock Protein Repigments Vitiligo Lesions in Sinclair Swine.
Vitiligo
Vitiligo: How do oxidative stress-induced autoantigens trigger autoimmunity?
Vitreoretinopathy, Proliferative
HBP21: A Novel Member of TPR Motif Family, as a Potential Chaperone of Heat Shock Protein 70 in Proliferative Vitreoretinopathy (PVR) and Breast Cancer.
Vitreoretinopathy, Proliferative
The anti-proliferative effect of inhibitor of telomerase on cultured retinal pigment epithelial cells.
Vulvar Vestibulitis
Defective regulation of the proinflammatory immune response in women with vulvar vestibulitis syndrome.
Vulvovaginitis
Vaginal heat shock protein expression in symptom-free women with a history of recurrent vulvovaginitis.
Waldenstrom Macroglobulinemia
Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
Warts
Comparative proteomic analysis of resistant and susceptible potato cultivars during Synchytrium endobioticum infestation.
Whipple Disease
Antibodies against recombinant heat shock protein 65 of Tropheryma whipplei in patients with and without Whipple's disease.
Whipple Disease
Peripheral T-Cell Reactivity to Heat Shock Protein 70 and Its Cofactor GrpE from Tropheryma whipplei Is Reduced in Patients with Classical Whipple's Disease.
Whooping Cough
Association of the beta gamma subunits of trimeric GTP-binding proteins with 90-kDa heat shock protein, hsp90.
Whooping Cough
groEL encodes a highly antigenic protein in Burkholderia pseudomallei.
Whooping Cough
Heterotrimeric Galphaq11 co-immunoprecipitates with surface-anchored GRP78 from plasma membranes of alpha2M*-stimulated macrophages.
Whooping Cough
Induction of humoral immunity in response to immunization with recombinant Mycobacterium bovis BCG expressing the S1 subunit of Bordetella pertussis toxin.
Whooping Cough
Priming to heat shock proteins in infants vaccinated against pertussis.
Whooping Cough
[Effect of heat shock protein 70 on nuclear factor-KappaB/inhibitor protein-alpha of nuclear factor-KappaB in brain edema induced by infection in rat]
Williams Syndrome
Heat shock protein 27 gene: chromosomal and molecular location and relationship to Williams syndrome.
Wilms Tumor
A carcinogenic trigger to study the function of tumor suppressor genes in Schmidtea mediterranea.
Wilms Tumor
Aldosterone signaling regulates the over-expression of claudin-4 and -8 at the distal nephron from type 1 diabetic rats.
Wilms Tumor
Differential expression of the heat shock protein 70 in the histological compartments of nephroblastomas.
Wilms Tumor
Heat shock protein 70/nitric oxide effect on stretched tubular epithelial cells linked to WT-1 cytoprotection during neonatal obstructive nephropathy.
Wilms Tumor
Heat shock protein 90 regulates the expression of Wilms' tumor 1 protein in myeloid leukemias.
Wilms Tumor
Micro RNAs are involved in activation of epicardium during zebrafish heart regeneration.
Wilms Tumor
STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer.
Wilms Tumor
The expression of HSP70 and HSP90alpha in children with Wilms tumor.
Wilms Tumor
Wilms' tumor 1-associating protein plays an aggressive role in diffuse large B-cell lymphoma and forms a complex with BCL6 via Hsp90.
Wiskott-Aldrich Syndrome
IL-17A regulates Eimeria tenella schizont maturation and migration in avian coccidiosis.
Xeroderma Pigmentosum
Induction of the 72-kD heat shock protein in xeroderma pigmentosum complementation group A fibroblasts.
Xeroderma Pigmentosum
Involvement of human heat shock protein 90 alpha in nicotine-induced apoptosis.
Yellow Fever
Drinking a hot blood meal elicits a protective heat shock response in mosquitoes.
Yellow Fever
Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulator.
Zika Virus Infection
A functional interaction between GRP78 and Zika virus E protein.
Zika Virus Infection
Glucose-Regulated Protein 78 Interacts with Zika Virus Envelope Protein and Contributes to a Productive Infection.
Zika Virus Infection
Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells.
Zoonoses
Hsp100 Molecular Chaperone ClpB and Its Role in Virulence of Bacterial Pathogens.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3.6.4.10 non-chaperonin molecular chaperone ATPase
more
top
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
