Disease on EC 3.6.3.43 - peptide-transporting ATPase

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DISEASE
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Adenocarcinoma
ABCB2 (TAP1) as the downstream target of SHH signaling enhances pancreatic ductal adenocarcinoma drug resistance.
Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
Adrenoleukodystrophy
ATP-binding-cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains.
Anemia
Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.
Fermented goat milk consumption during anaemia recovery: ergogenic effect and improvement of skeletal muscle homeostasis.
Anemia, Sideroblastic
Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.
Arthritis, Rheumatoid
Peptide transporter genes (TAP) polymorphisms and genetic susceptibility to rheumatoid arthritis.
Autoimmune Diseases
Genetics of autoimmune diseases.
Brain Injuries, Traumatic
Apoptosis and functional changes of dipeptide transporter (PepT1) in the rat small intestine after traumatic brain injury.
Breast Neoplasms
5-Fluorouracil treatment alters the expression of intestinal transporters in rats.
BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia.
Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: possible functional consequences.
Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.
Correlation between Multi-Drug Resistance-Associated Membrane Transport in Clonal Cancer Cells and the Cell Cycle Phase.
Drug transporters in the lung--do they play a role in the biopharmaceutics of inhaled drugs?
Expression and localisation of breast cancer resistance protein (BCRP) in human fetal membranes and decidua and the influence of labour at term.
Expression and localization of BCRP, MRP1 and MRP2 in intestines, liver and kidney in horse.
Expression of the BCRP gene (ABCG2/MXR/ABCP) in childhood acute lymphoblastic leukaemia.
HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway.
Impact of a high-cholesterol diet on expression levels of Niemann-Pick C1-like 1 and intestinal transporters in rats and mice.
In Vitro Models used in Drug Discovery: Drug absorption and Metabolism.
Microvillus-Specific Protein Tyrosine Phosphatase SAP-1 Plays a Role in Regulating the Intestinal Paracellular Transport of Macromolecules.
Overexpression of microRNA-24 increases the sensitivity to paclitaxel in drug-resistant breast carcinoma cell lines via targeting ABCB9.
P-glycoprotein and breast cancer resistance protein expression and function at the blood-brain barrier and blood-cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats.
Selective Fusion of Heterogeneous Classifiers for Predicting Substrates of Membrane Transporters.
Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.
Tissue Distribution, Ontogeny, and Hormonal Regulation of Xenobiotic Transporters in Mouse Kidneys.
[MDR (multidrug resistance) in hepatocarcinoma clinical-therapeutic implications]
Burkitt Lymphoma
Class I processing-defective Burkitt's lymphoma cells are recognized efficiently by CD4+ EBV-specific CTLs.
Engagement of CD40 antigen with soluble CD40 ligand up-regulates peptide transporter expression and restores endogenous processing function in Burkitt's lymphoma cells.
Carcinogenesis
Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.
Carcinoma
CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma.
Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma.
Nrf2 regulates the expression of the peptide transporter PEPT1 in the human colon carcinoma cell line Caco-2.
Oseltamivir (TamifluTM) is a substrate of PEPT1.
Specific expression of proton-coupled oligopeptide transporter 1 in primary hepatocarcinoma-a novel strategy for tumor-targeted therapy.
Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine.
Carcinoma, Hepatocellular
Targeting PEPT1: a novel strategy to improve the antitumor efficacy of doxorubicin in human hepatocellular carcinoma therapy.
Carcinoma, Non-Small-Cell Lung
ABCA3 Phenotype in Non-Small Cell Lung Cancer Indicates Poor Outcome.
MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9.
Cardiomyopathies
Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation.
Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export.
Cholera
Inhibition of the H+/peptide cotransporter in the human intestinal cell line Caco-2 by cyclic AMP.
Coinfection
Differential processing of influenza nucleoprotein in human and mouse cells.
Colitis
Colonic Expression of the Peptide Transporter PEPT1 Is Downregulated During Intestinal Inflammation and Is Not Required for NOD2-dependent Immune Activation.
Colonic miRNA expression/secretion, regulated by intestinal epithelial PepT1, plays an important role in cell-to-cell communication during colitis.
Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.
IL-16 induces intestinal inflammation via PepT1 upregulation in a pufferfish model: new insights into the molecular mechanism of inflammatory bowel disease.
MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1.
PepT1 expressed in immune cells has an important role in promoting the immune response during experimentally induced colitis.
The PepT1-NOD2 Signaling Pathway Aggravates Induced Colitis in Mice.
Colitis, Ulcerative
Inhibitory Potency of Marketed Drugs for Ulcerative Colitis and Crohn's Disease on PEPT1.
MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1.
Peptide Receptor-Targeted Fluorescent Probe: Visualization and Discrimination between Chronic and Acute Ulcerative Colitis.
The peptide transporter PEPT1 is expressed in distal colon in rodents and humans and contributes to water absorption.
Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine.
Colonic Neoplasms
Synthesis of CDDO-Amino Acid-Nitric Oxide Donor Trihybrids as Potential Antitumor Agents against Both Drug-Sensitive and Drug-Resistant Colon Cancer.
Transport of the Photodynamic Therapy Agent 5-Aminolevulinic Acid by Distinct H+-Coupled Nutrient Carriers Co-expressed in the Small Intestine.
Colorectal Neoplasms
Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.
Common Variable Immunodeficiency
Major histocompatibility haplotypes associated with immunoglobulin-A deficiency and common variable immunodeficiency: analysis of the peptide transporter genes TAP1 and TAP2.
Crohn Disease
Inhibitory Potency of Marketed Drugs for Ulcerative Colitis and Crohn's Disease on PEPT1.
The peptide transporter PEPT1 is expressed in distal colon in rodents and humans and contributes to water absorption.
Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine.
Cryptosporidiosis
Cryptosporidiosis induces a transient upregulation of the oligopeptides transporter (PepT1) activity in neonatal rats.
Evidence for intestinal heterogenic expression of di-tripeptides transporter PepT1 during experimental cryptosporidiosis in neonatal rats.
Intestinal peptide transporter PepT1 is over-expressed during acute cryptosporidiosis in suckling rats as a result of both malnutrition and experimental parasite infection.
Cystic Fibrosis
ATP-binding-cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains.
Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics.
Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung.
Impaired transporter associated with antigen processing (TAP) function attributable to a single amino acid alteration in the peptide TAP subunit TAP1.
The cubicon method for concentrating membrane proteins in the cubic mesophase.
Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein.
[Expression, localization and functional aspects of the peptide transporter PEPT2 in the normal respiratory tract and in cystic fibrosis]
[MDR (multidrug resistance) in hepatocarcinoma clinical-therapeutic implications]
Diabetes Mellitus
Intestinal absorption of cephalexin in diabetes mellitus model rats.
P-glycoprotein and breast cancer resistance protein expression and function at the blood-brain barrier and blood-cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats.
Diabetes Mellitus, Type 1
Linkage of faulty major histocompatibility complex class I to autoimmune diabetes.
MHC class I-mediated antigen presentation and induction of CD8+ cytotoxic T-cell responses in autoimmune diabetes-prone NOD mice.
Protection from insulin-dependent diabetes mellitus is linked to a peptide transporter gene.
Diabetes Mellitus, Type 2
Intestinal absorption of cephalexin in diabetes mellitus model rats.
Drug-Related Side Effects and Adverse Reactions
Targeting PEPT1: a novel strategy to improve the antitumor efficacy of doxorubicin in human hepatocellular carcinoma therapy.
Enteritis
Mechanism of inhibition of proton: dipeptide co-transport during chronic enteritis in the mammalian small intestine.
Fetal Growth Retardation
Intrauterine Growth Restriction Delays Feeding-Induced Gut Adaptation in Term Newborn Pigs.
Fibrosarcoma
Tissue selective drug delivery utilizing carrier-mediated transport systems.
Gastrointestinal Neoplasms
Reactive oxygen species involved cancer cellular specific 5-aminolevulinic acid uptake in gastric epithelial cells.
Search for novel target molecules for the effective treatment or prevention of colorectal cancer.
Glioma
Role of PEPT2 in glycylsarcosine transport in astrocyte and glioma cultures.
Hepatitis C
Dissimilar expression of multidrug resistance mdr1 and bcrp by the replication of hepatitis C virus: role of the nonstructural 5A protein.
Herpes Simplex
Dipeptide monoester ganciclovir prodrugs for treating HSV-1-induced corneal epithelial and stromal keratitis: in vitro and in vivo evaluations.
The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex (MHC)-encoded peptide transporter associated with antigen processing (TAP), maps to the NH2-terminal 35 residues.
Hyperthyroidism
Decreased activity and expression of intestinal oligopeptide transporter PEPT1 in rats with hyperthyroidism in vivo.
Hypoglycemia
Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics.
Hypothyroidism
Hypothyroidism induces expression of the peptide transporter PEPT2.
Infection
Alterations in hexose, amino acid and peptide transporter expression in intestinal epithelial cells during Nippostrongylus brasiliensis infection in the rat.
Campylobacter jejuni influences the expression of nutrient transporter genes in the intestine of chickens.
Effects of fluoroquinolone treatment on MDR1 and MRP2 mRNA expression in Escherichia coli-infected chickens.
Induction of the rainbow trout MHC class I pathway during acute IHNV infection.
Intestinal peptide transporter PepT1 is over-expressed during acute cryptosporidiosis in suckling rats as a result of both malnutrition and experimental parasite infection.
Modulation of transporter associated with antigen processing (TAP)-mediated peptide import into the endoplasmic reticulum by flavivirus infection.
Recovery of functional peptide transporter PepT1 in budded baculovirus fraction.
Xylanase supplementation of a wheat-based diet improved nutrient digestion and mRNA expression of intestinal nutrient transporters in broiler chickens infected with Clostridium perfringens.
Inflammatory Bowel Diseases
Colonic Expression of the Peptide Transporter PEPT1 Is Downregulated During Intestinal Inflammation and Is Not Required for NOD2-dependent Immune Activation.
IL-16 induces intestinal inflammation via PepT1 upregulation in a pufferfish model: new insights into the molecular mechanism of inflammatory bowel disease.
Inhibitory Potency of Marketed Drugs for Ulcerative Colitis and Crohn's Disease on PEPT1.
PepT1 mediates colon damage by transporting fMLP in rats with bowel resection.
PepT1 mediates transport of the proinflammatory bacterial tripeptide L-Ala-{gamma}-D-Glu-meso-DAP in intestinal epithelial cells.
PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease.
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.
The role and pathophysiological relevance of membrane transporter PepT1 in intestinal inflammation and inflammatory bowel disease.
Kidney Failure, Chronic
Determination of renal porphyrin handling in rats suffering from different kinds of chronic renal failure (CRF): uranyl nitrate (UN) induced fibrosis or 5/6-nephrectomy (5/6NX).
Increased protein level of PEPT1 intestinal H+-peptide cotransporter upregulates absorption of glycylsarcosine and ceftibuten in 5/6 nephrectomized rats.
Physiological and pharmacological implications of peptide transporters, PEPT1 and PEPT2.
Upregulation of H(+)-peptide cotransporter PEPT2 in rat remnant kidney.
Leukemia, Erythroblastic, Acute
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.
Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis.
Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes.
Leukemia, Myeloid, Acute
Exclusion of ABCB8 and ABCB10 as cancer candidate genes in acute myeloid leukemia.
Liver Diseases
Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: possible functional consequences.
Lung Neoplasms
ABCA3 Phenotype in Non-Small Cell Lung Cancer Indicates Poor Outcome.
MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9.
Molecular mechanisms of pulmonary peptidomimetic drug and peptide transport.
Lymphoma
A longitudinal study of ABC transporter expression in canine multicentric lymphoma.
Lymphoma, B-Cell
A longitudinal study of ABC transporter expression in canine multicentric lymphoma.
Malnutrition
Intestinal peptide transporter PepT1 is over-expressed during acute cryptosporidiosis in suckling rats as a result of both malnutrition and experimental parasite infection.
Measles
Antigen loading of MHC class I molecules in the endocytic tract.
Melanoma
ABCB8 mediates doxorubicin resistance in melanoma cells by protecting the mitochondrial genome.
Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells.
Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps.
Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma.
Mapping ATP-binding cassette transporter gene expression profiles in melanocytes and melanoma cells.
Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8.
New treatment options for patients with melanoma: review of melanoma-derived T-cell epitope-based peptide vaccines.
Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen.
Tumor escape from immune recognition: loss of HLA-A2 melanoma cell surface expression is associated with a complex rearrangement of the short arm of chromosome 6.
Melanoma, Experimental
Characterization of the major histocompatibility complex class I deficiencies in B16 melanoma cells.
Neoplasms
5-Aminolevulinic Acid Fluorescence in Detection of Peritoneal Metastases.
A longitudinal study of ABC transporter expression in canine multicentric lymphoma.
A novel category of antigens enabling CTL immunity to tumor escape variants: Cinderella antigens.
Application of an LC-MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique.
Atorvastatin synergizes with IFN-? in treating human non-small cell lung carcinomas via potent inhibition of RhoA activity.
Cancer cell-targeted drug delivery utilizing oligopeptide transport activity.
Cancer Detection Using a PET Tracer, 11C-Glycylsarcosine, Targeted to H+/Peptide Transporter.
Carrier-mediated transport of oligopeptides in the human fibrosarcoma cell line HT1080.
CD8+ T Cell Responses against TAP-Inhibited Cells Are Readily Detected in the Human Population.
Class I processing-defective Burkitt's lymphoma cells are recognized efficiently by CD4+ EBV-specific CTLs.
Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells.
Coordinate downregulation of multiple MHC class I antigen processing genes in chemical-induced murine tumor cell lines of distinct origin.
Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.
Current issues in the diagnosis and treatment of Sjögren's syndrome.
Delta-aminolevulinic acid transport in cancer cells of the human extrahepatic biliary duct.
Dominant contribution of the proteasome and metalloproteinases to TAP-independent MHC-I peptide repertoire.
Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy.
Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines.
Effect of Janus Kinase 3 on the Peptide Transporters PEPT1 and PEPT2.
Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability.
Exclusion of ABCB8 and ABCB10 as cancer candidate genes in acute myeloid leukemia.
Functional deficiencies of components of the MHC class I antigen pathway in human tumors of epithelial origin.
Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients.
Induction of protective CTL immunity against peptide transporter TAP-deficient tumors through dendritic cell vaccination.
Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8.
Modulation of antigen processing and presentation by persistent virus infections and in tumors.
New treatment options for patients with melanoma: review of melanoma-derived T-cell epitope-based peptide vaccines.
Peptide transporter (TAP-1 and TAP-2)-independent endogenous processing of Epstein-Barr virus (EBV) latent membrane protein 2A: implications for cytotoxic T-lymphocyte control of EBV-associated malignancies.
Rational design of gold(III)-dithiocarbamato peptidomimetics for the targeted anticancer chemotherapy.
Reactive oxygen species involved cancer cellular specific 5-aminolevulinic acid uptake in gastric epithelial cells.
Search for novel target molecules for the effective treatment or prevention of colorectal cancer.
Specific expression of proton-coupled oligopeptide transporter 1 in primary hepatocarcinoma-a novel strategy for tumor-targeted therapy.
Spontaneous resistance to acute T-cell leukaemias in TCRV gamma 1.1J gamma 4C gamma 4 transgenic mice.
Study of the mechanisms of uptake of 5-aminolevulinic acid derivatives by PEPT1 and PEPT2 transporters as a tool to improve photodynamic therapy of tumours.
Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
Targeting PEPT1: a novel strategy to improve the antitumor efficacy of doxorubicin in human hepatocellular carcinoma therapy.
Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.
The varicellovirus-encoded TAP inhibitor UL49.5 regulates the presentation of CTL epitopes by Qa-1b1.
Tissue selective drug delivery utilizing carrier-mediated transport systems.
Toward the selective delivery of chemotherapeutics into tumor cells by targeting Peptide transporters: tailored gold-based anticancer peptidomimetics.
Transport of the Photodynamic Therapy Agent 5-Aminolevulinic Acid by Distinct H+-Coupled Nutrient Carriers Co-expressed in the Small Intestine.
Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen.
Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine.
Tumour surveillance: missing peptides and MHC molecules.
Upregulation of peptide transporters PEPT1 and PEPT2 by Janus kinase JAK2.
Variation of peptide transporter (PepT1 and HPT1) expression in Caco-2 cells as a function of cell origin.
[Active drug delivery by heterologous expression of membrane transporters]
Obesity
Disturbed intestinal nitrogen homeostasis in a mouse model of high-fat diet-induced obesity and glucose intolerance.
How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans.
Long-term effect of leptin on H+-coupled peptide cotransporter 1 activity and expression in vivo: evidence in leptin-deficient mice.
Mice lacking the intestinal peptide transporter display reduced energy intake and a subtle maldigestion/-absorption that protects them from diet-induced obesity.
Reduced intestinal absorption of dipeptides via PepT1 in mice with diet-induced obesity is associated with leptin receptor down-regulation.
Rosiglitazone and Metformin Have Opposite Effects on Intestinal Absorption of Oligopeptides via the Proton-Dependent PepT1 Transporter.
Osteosarcoma
Endosialin?expressing bone sarcoma stem?like cells are highly tumor?initiating and invasive.
Pancreatic Neoplasms
A new target ligand Ser-Glu for PEPT1-overexpressing cancer imaging.
Drug efflux transporter MRP5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil.
Viral envelope protein gp64 transgenic mouse facilitates the generation of monoclonal antibodies against exogenous membrane proteins displayed on baculovirus.
Pancreatitis
Characterization of immunoreactive trypsinogen activation peptide in urine in acute pancreatitis.
Parasitic Diseases
Intestinal peptide transporter PepT1 is over-expressed during acute cryptosporidiosis in suckling rats as a result of both malnutrition and experimental parasite infection.
peptide-transporting atpase deficiency
CD1 expression is not affected by human peptide transporter deficiency.
Human peptide transporter deficiency: importance of HLA-B in the presentation of TAP-independent EBV antigens.
Porphyrias, Hepatic
Peptide transporter 2 (PEPT2) expression in brain protects against 5-aminolevulinic acid neurotoxicity.
Protein Deficiency
Board-invited review: Peptide absorption and utilization: Implications for animal nutrition and health.
Protoporphyria, Erythropoietic
Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.
Pulmonary Fibrosis
[Expression of PEPT2 mRNA in lung tissue of rats with pulmonary fibrosis].
Renal Insufficiency
Dietary Inorganic Phosphorus Regulates the Intestinal Peptide Transporter PepT1.
Increased protein level of PEPT1 intestinal H+-peptide cotransporter upregulates absorption of glycylsarcosine and ceftibuten in 5/6 nephrectomized rats.
Starvation
A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.
CsrA regulates translation of the Escherichia coli carbon starvation gene, cstA, by blocking ribosome access to the cstA transcript.
Ferri-bacillibactin uptake and hydrolysis in Bacillus subtilis.
Induction of intestinal peptide transporter 1 expression during fasting is mediated via peroxisome proliferator-activated receptor alpha.
PepT1 mRNA expression is induced by starvation and its level correlates with absorptive transport of cefadroxil longitudinally in the rat intestine.
Peptide transporter in the rat small intestine: ultrastructural localization and the effect of starvation and administration of amino acids.
Regulation of the pstSCAB operon in Corynebacterium glutamicum by the regulator of acetate metabolism RamB.
Role of symbiotic auxotrophy in the Rhizobium-legume symbioses.
Stomach Neoplasms
Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells in vitro.
Regulation of human peptide transporter 1 (PEPT1) in gastric cancer cells by anticancer drugs.
Stroke
Isolation of peptide transport system-6 from brain endothelial cells: therapeutic effects with antisense inhibition in Alzheimer and stroke models.
Molecular Disruption of the Power Stroke in the ATP-binding Cassette Transport Protein MsbA.
Tuberculosis
Conservation of the binding site for the arginine repressor in all bacterial lineages.
Mycobacterium tuberculosis isolate with a distinct genomic identity overexpresses a tap-like efflux pump.
Urinary Bladder Neoplasms
Expression levels of PEPT1 and ABCG2 play key roles in 5-aminolevulinic acid (ALA)-induced tumor-specific protoporphyrin IX (PpIX) accumulation in bladder cancer.
Expression of ferrochelatase has a strong correlation in protoporphyrin IX accumulation with photodynamic detection of bladder cancer.
Systemic transduction of p16INK4A antitumor peptide inhibits the growth of MBT-2 mouse bladder tumor cell line grafts.
Vaccinia
Differential processing of influenza nucleoprotein in human and mouse cells.
Vesicular Stomatitis
MHC class I heavy chain-dependent expression of discontinuous antigenic epitopes on beta 2-microglobulinb is inducible with peptide-ligand.
Virus Diseases
Induction of the rainbow trout MHC class I pathway during acute IHNV infection.