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Disease on EC 3.6.1.74 - mRNA 5'-phosphatase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence.
Adenocarcinoma of Lung
Upregulation of the Coatomer Protein Complex Subunit beta 2 (COPB2) Gene Targets microRNA-335-3p in NCI-H1975 Lung Adenocarcinoma Cells to Promote Cell Proliferation and Migration.
African Swine Fever
African swine fever virus NP868R capping enzyme promotes reovirus rescue during reverse genetics by promoting reovirus protein expression, virion assembly, and RNA incorporation into infectious virions.
Albinism, Oculocutaneous
A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration.
Amyotrophic Lateral Sclerosis
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Anaphylaxis
PAFAH1B2 is a HIF1a target gene and promotes metastasis in pancreatic cancer.
Anemia, Sickle Cell
A genome-editing strategy to treat ?-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
Angelman Syndrome
High-resolution mapping of the gamma-aminobutyric acid receptor subunit beta 3 and alpha 5 gene cluster on chromosome 15q11-q13, and localization of breakpoints in two Angelman syndrome patients.
Arthritis, Rheumatoid
In silico drug design of inhibitor of nuclear factor kappa B kinase subunit beta inhibitors from 2-acylamino-3-aminothienopyridines based on quantitative structure-activity relationships and molecular docking.
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
Ataxia
Broader phenotypic traits and widespread brain hypometabolism in spinocerebellar ataxia 27.
Ataxia Telangiectasia
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy.
Autoimmune Diseases
A case-control study on association of proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1) polymorphisms and their transcript levels in vitiligo from Gujarat.
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
Azoospermia
Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survival.
The expression of microRNAs and exposure to environmental contaminants related to human health: a review.
Bile Duct Neoplasms
microRNA-329 suppresses epithelial-to-mesenchymal transition and lymph node metastasis in bile duct cancer by inhibiting laminin subunit beta 3.
Bluetongue
Guanylyltransferase and RNA 5'-triphosphatase activities of the purified expressed VP4 protein of bluetongue virus.
Breast Neoplasms
COPB2 is up-regulated in breast cancer and plays a vital role in the metastasis via N-cadherin and Vimentin.
Gene expression profiling detects gene amplification and differentiates tumor types in breast cancer.
Immunohistochemical expression of subunit beta HCG in breast cancer.
PSMB5 is associated with proliferation and drug resistance in triple-negative breast cancer.
Bulbo-Spinal Atrophy, X-Linked
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Carcinogenesis
Human G3BP1 interacts with beta-F1-ATPase mRNA and inhibits its translation.
Carcinoma
Clinical Significance of Integrin Subunit Beta 4 in Head and Neck Squamous Cell Carcinoma.
Coatomer subunit beta 2 (COPB2), identified by label-free quantitative proteomics, regulates cell proliferation and apoptosis in human prostate carcinoma cells.
High G protein subunit beta 4 protein level is correlated to poor prognosis of urothelial carcinoma.
Integrin Subunit beta 8 (ITGB8) Upregulation Is an Independent Predictor of Unfavorable Survival of High-Grade Serous Ovarian Carcinoma Patients.
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
The clinical significance and potential molecular mechanism of integrin subunit beta 4 in laryngeal squamous cell carcinoma.
Carcinoma, Hepatocellular
Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability.
COPB2: A Novel Prognostic Biomarker That Affects Progression of HCC.
Carcinoma, Non-Small-Cell Lung
Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.
Carcinoma, Renal Cell
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
Carcinoma, Squamous Cell
Clinical Significance of Integrin Subunit Beta 4 in Head and Neck Squamous Cell Carcinoma.
Cardiotoxicity
Targeting ?2 subunit of Na+/K+-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca2.
Cardiovascular Diseases
The expression of microRNAs and exposure to environmental contaminants related to human health: a review.
Chagas Disease
Divalent metal requirements for catalysis and stability of the RNA triphosphatase from Trypanosoma cruzi.
Cholera
Day-night differences in neural activation in histaminergic and serotonergic areas with putative projections to the cerebrospinal fluid in a diurnal brain.
Degeneration of primary afferent terminals following brachial plexus extensive avulsion injury in rats.
Intraspinal sprouting of unmyelinated pelvic afferents after complete spinal cord injury is correlated with autonomic dysreflexia induced by visceral pain.
Plasticity of lumbosacral propriospinal neurons is associated with the development of autonomic dysreflexia after thoracic spinal cord transection.
Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice.
Classical Swine Fever
Hemoglobin Subunit Beta Interacts with the Capsid Protein and Antagonizes the Growth of Classical Swine Fever Virus.
Interaction of Structural Glycoprotein E2 of Classical Swine Fever Virus with Protein Phosphatase 1 Catalytic Subunit Beta (PPP1CB).
COVID-19
Erythropoietin-induced hemoglobin subunit beta may stimulate innate immune RNA virus pattern recognition, suppress reactive oxygen species, reduce ACE2 viral doorway opening, and neutrophil extracellular traps against COVID-19.
Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase.
NF-?B signalling as a pharmacological target in COVID-19: potential roles for IKK? inhibitors.
Dengue
Analysis of the nucleoside triphosphatase, RNA triphosphatase, and unwinding activities of the helicase domain of dengue virus NS3 protein.
Expression, purification, and characterization of the RNA 5'-triphosphatase activity of dengue virus type 2 nonstructural protein 3.
The RNA helicase, nucleotide 5'-triphosphatase, and RNA 5'-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core.
The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase.
Diabetes Mellitus, Type 2
Whole exome sequencing suggests LAMB3 as a susceptibility gene for morbid obesity.
Diabetic Neuropathies
Toll-like receptors and inflammation in metabolic neuropathy; a role in early versus late disease?
Diphtheria
A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
Encephalitis, Japanese
Ilheus virus (Flaviviridae, Flavivirus) is closely related to Japanese encephalitis virus complex.
Encephalomyelitis, Venezuelan Equine
mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research.
Epilepsy
ATP Synthase Subunit Beta Immunostaining is Reduced in the Sclerotic Hippocampus of Epilepsy Patients.
Failure to confirm association of a polymorphism in KCNMB4 gene with mesial temporal lobe epilepsy.
Proteomic differences in the hippocampus and cortex of epilepsy brain tissue.
Epilepsy, Temporal Lobe
Failure to confirm association of a polymorphism in KCNMB4 gene with mesial temporal lobe epilepsy.
Exanthema
Successful treatment of a novel type I interferonopathy due to a de novo PSMB9 gene mutation with a Janus kinase inhibitor.
Glaucoma
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
Glioma
High expression of COPB2 predicts adverse outcomes: A potential therapeutic target for glioma.
In silico analysis identified miRNA?based therapeutic agents against glioblastoma multiforme.
Heart Defects, Congenital
De novo missense variants in PPP1CB are associated with intellectual disability and congenital heart disease.
Hepatitis B
Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability.
Hepatitis B, Chronic
Association of IFNAR2 and IL10RB genes in chronic hepatitis B virus infection.
Hepatitis C
RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.
Hepatitis E
RNA 5'-triphosphatase activity of the hepatitis E virus helicase domain.
Huntington Disease
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Hypertension
CACNB2 is associated with aberrant RAS-MAPK signaling in hypertensive Dahl Salt-Sensitive rats.
Hypertension, Pulmonary
Successful treatment of a novel type I interferonopathy due to a de novo PSMB9 gene mutation with a Janus kinase inhibitor.
Infections
Analysis and identification of tyrosine phosphorylated proteins in hemocytes of Litopenaeus vannamei infected with WSSV.
Association of IFNAR2 and IL10RB genes in chronic hepatitis B virus infection.
Identification of key genes and pathways associated with different immune statuses of hepatitis B virus infection.
Plasma phosphoproteome and differential plasma phosphoproteins with opisthorchis viverrini-related cholangiocarcinoma.
Infertility, Male
Transcriptional alterations of genes related to fertility decline in male rats induced by chronic sleep restriction.
Inflammatory Bowel Diseases
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
Intellectual Disability
De novo missense variants in PPP1CB are associated with intellectual disability and congenital heart disease.
Leukemia
Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways.
Lipodystrophy
CANDLE Syndrome: a report of a novel mutation and review of the literature.
Liver Cirrhosis
Evolving Up-regulation of Biliary Fibrosis-Related Extracellular Matrix Molecules After Successful Portoenterostomy.
Lung Neoplasms
Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.
Lymphatic Metastasis
microRNA-329 suppresses epithelial-to-mesenchymal transition and lymph node metastasis in bile duct cancer by inhibiting laminin subunit beta 3.
Lymphoma
Comparative analysis of testis transcriptomes associated with male infertility in triploid cyprinid fish.
Lymphoma, B-Cell
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder.
In vitro long-term culture of isolated ovine preantral follicles: Influence of ethanol on steroid production, oocyte meiotic resumption, and metabolomic profile.
The expression of microRNAs and exposure to environmental contaminants related to human health: a review.
Lymphoma, Follicular
Proteasome Subunit Beta Type 1 P11A Polymorphism Is a New Prognostic Marker in Multiple Myeloma.
Lymphoma, T-Cell
Primary gastric T-cell lymphoma of suppressor-cytotoxic (CD8+) phenotype: discordant expression of T-cell receptor subunit beta F1, CD7, and CD3 antigens.
Malaria
A yeast-like mRNA capping apparatus in Plasmodium falciparum.
Polymorphisms of transporter associated with antigen processing type 1 (TAP1), proteasome subunit beta type 9 (PSMB9) and their common promoter in African children with different manifestations of malaria.
Megalencephaly
De novo missense variants in PPP1CB are associated with intellectual disability and congenital heart disease.
Melanoma
cDNA sequence of the human integrin beta 5 subunit.
Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells.
Immunohistological examination of the relationship between metastatic potential and expression of adhesion molecules and 'selectins' on melanoma cells.
Memory Disorders
Overexpression of Kcnmb2 in Dorsal CA1 of Offspring Mice Rescues Hippocampal Dysfunction Caused by a Methyl Donor-Rich Paternal Diet.
Microphthalmos
Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence.
Multiple Myeloma
Proteasome Subunit Beta Type 1 P11A Polymorphism Is a New Prognostic Marker in Multiple Myeloma.
Muscular Atrophy
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Mycoses
Study of the essentiality of the Aspergillus fumigatus triA gene, encoding RNA triphosphatase, using the heterokaryon rescue technique and the conditional gene expression driven by the alcA and niiA promoters.
Myoma
Gene expression changes in uterine myomas in response to ulipristal acetate treatment.
Myositis
Successful treatment of a novel type I interferonopathy due to a de novo PSMB9 gene mutation with a Janus kinase inhibitor.
Neoplasm Metastasis
CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3.
microRNA-329 suppresses epithelial-to-mesenchymal transition and lymph node metastasis in bile duct cancer by inhibiting laminin subunit beta 3.
Neoplasms
A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration.
Activation of the Unfolded Protein Response via Inhibition of Protein Disulfide Isomerase Decreases the Capacity for DNA Repair to Sensitize Glioblastoma to Radiotherapy.
Cancer-associated fibroblasts promote aggressive gastric cancer phenotypes via heat shock factor 1-mediated secretion of extracellular vesicles.
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy.
Effects of ELF magnetic fields on protein expression profile of human breast cancer cell MCF7.
Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survival.
Expression of possible targets for new proteasome inhibitors in diffuse large B-cell lymphoma.
Gene expression changes in uterine myomas in response to ulipristal acetate treatment.
Genomic and Clinicopathologic Features of Primary Myelofibrosis With Isolated 13q Deletion.
Host-Viral Interactions Revealed among Shared Transcriptomics Signatures of ARDS and Thrombosis: A Clue into COVID-19 Pathogenesis.
Identification of collaborative activities with oxidative phosphorylation in bipolar disorder.
Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53.
Identification of key miRNA-gene pairs in gastric cancer through integrated analysis of mRNA and miRNA microarray.
In silico drug design of inhibitor of nuclear factor kappa B kinase subunit beta inhibitors from 2-acylamino-3-aminothienopyridines based on quantitative structure-activity relationships and molecular docking.
Integrated analysis of whole genome exon array and array-comparative genomic hybridization in gastric and colorectal cancer cells.
MicroRNA-183-5p Inhibits Aggressiveness of Cervical Cancer Cells by Targeting Integrin Subunit Beta 1 (ITGB1).
microRNA-329 suppresses epithelial-to-mesenchymal transition and lymph node metastasis in bile duct cancer by inhibiting laminin subunit beta 3.
microRNA-371a-3p as informative biomarker for the follow-up of testicular germ cell cancer patients.
Multi-Omics Data Analyses Construct a Six Immune-Related Genes Prognostic Model for Cervical Cancer in Tumor Microenvironment.
Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization.
Protein profile changes in the human breast cancer cell line MCF-7 in response to SEL1L gene induction.
TGFB1/INHBA Homodimer/Nodal-SMAD2/3 Signaling Network: A Pivotal Molecular Target in PDAC Treatment.
The expression of microRNAs and exposure to environmental contaminants related to human health: a review.
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Transcriptional alterations of genes related to fertility decline in male rats induced by chronic sleep restriction.
Upregulation of LAMB1 via ERK/c-Jun Axis Promotes Gastric Cancer Growth and Motility.
Upregulation of the Coatomer Protein Complex Subunit beta 2 (COPB2) Gene Targets microRNA-335-3p in NCI-H1975 Lung Adenocarcinoma Cells to Promote Cell Proliferation and Migration.
Whole-transcriptomic Profile of SK-MEL-3 Melanoma Cells Treated with the Histone Deacetylase Inhibitor: Trichostatin A.
Neoplasms, Germ Cell and Embryonal
microRNA-371a-3p as informative biomarker for the follow-up of testicular germ cell cancer patients.
Neuralgia
IKBKB siRNA-Encapsulated Poly (Lactic-co-Glycolic Acid) Nanoparticles Diminish Neuropathic Pain by Inhibiting Microglial Activation.
Neuroblastoma
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Neurodegenerative Diseases
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Obesity, Morbid
Whole exome sequencing suggests LAMB3 as a susceptibility gene for morbid obesity.
Optic Atrophy, Autosomal Dominant
Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes NRF2-Independent Mitochondrial Fusion through CXCR4/PSMB5-Mediated Drp1 Degradation in Endothelial Cells.
Osteosarcoma
Transcriptional activation of CBF? by CDK11p110 is necessary to promote osteosarcoma cell proliferation.
Pancreatic Neoplasms
TGFB1/INHBA Homodimer/Nodal-SMAD2/3 Signaling Network: A Pivotal Molecular Target in PDAC Treatment.
The expression and clinical prognostic value of protein phosphatase 1 catalytic subunit beta in pancreatic cancer.
Paramyxoviridae Infections
Human parainfluenza virus type 2 L protein regions required for interaction with other viral proteins and mRNA capping.
Parkinson Disease
LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Pemphigoid, Bullous
Tyrosine phosphorylation: a critical component in the formation of hemidesmosomes.
Peste-des-Petits-Ruminants
The large protein 'L' of Peste-des-petits-ruminants virus exhibits RNA triphosphatase activity, the first enzyme in mRNA capping pathway.
Prostatic Neoplasms
Coatomer subunit beta 2 (COPB2), identified by label-free quantitative proteomics, regulates cell proliferation and apoptosis in human prostate carcinoma cells.
Psoriasis
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
Pulmonary Disease, Chronic Obstructive
Prediction and identification of immune genes related to the prognosis of patients with colon adenocarcinoma and its mechanisms.
Rabies
The Rabies Virus L Protein Catalyzes mRNA Capping with GDP Polyribonucleotidyltransferase Activity.
Transcriptional Control and mRNA Capping by the GDP Polyribonucleotidyltransferase Domain of the Rabies Virus Large Protein.
Rectal Neoplasms
Identifications of Candidate Genes Significantly Associated With Rectal Cancer by Integrated Bioinformatics Analysis.
Retinitis Pigmentosa
In Vivo Potency Testing of Subretinal rAAV5.hCNGB1 Gene Therapy in the Cngb1 Knockout Mouse Model of Retinitis Pigmentosa.
Retinoblastoma
Genomic and Clinicopathologic Features of Primary Myelofibrosis With Isolated 13q Deletion.
Rinderpest
A carboxy terminal domain of the L protein of rinderpest virus possesses RNA triphosphatase activity - The first enzyme in the viral mRNA capping pathway.
The RNA triphosphatase domain of L protein of Rinderpest virus exhibits pyrophosphatase and tripolyphosphatase activities.
Sandhoff Disease
[Recent advances in molecular genetics of GM2 gangliosidosis]
Sarcoma
Expression of F-actin-capping protein subunit beta, CAPZB, is associated with cell growth and motility in epithelioid sarcoma.
Sepsis
Early diagnosis of sepsis using serum hemoglobin subunit Beta.
Targeting Neuropilin-1 Suppresses the Stability of CD4+ CD25+ Regulatory T Cells via the NF-?B Signaling Pathway in Sepsis.
Skin Diseases
CANDLE Syndrome: a report of a novel mutation and review of the literature.
Sleep Deprivation
Transcriptional alterations of genes related to fertility decline in male rats induced by chronic sleep restriction.
Spinocerebellar Ataxias
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Squamous Cell Carcinoma of Head and Neck
Clinical Significance of Integrin Subunit Beta 4 in Head and Neck Squamous Cell Carcinoma.
The clinical significance and potential molecular mechanism of integrin subunit beta 4 in laryngeal squamous cell carcinoma.
Starvation
TaNBP1, a guanine nucleotide-binding subunit gene of wheat, is essential in the regulation of N starvation adaptation via modulating N acquisition and ROS homeostasis.
Stomatitis, Aphthous
Salivary proteome of aphthous stomatitis reveals the participation of vitamin metabolism, nutrients, and bacteria.
Tay-Sachs Disease
[Recent advances in molecular genetics of GM2 gangliosidosis]
Tay-Sachs Disease, AB Variant
[Recent advances in molecular genetics of GM2 gangliosidosis]
Thrombasthenia
A novel missense variant in the RASGRP2 gene in patients with moderate to severe bleeding disorder.
Further characterization of the thrombasthenia-related idiotype OG. Antiidiotype defines a novel epitope(s) shared by fibrinogen B beta chain, vitronectin, and von Willebrand factor and required for binding to beta 3.
Repertoire cloning of a human IgG inhibitor of alpha IIB beta 3 function. The OG idiotype.
Thrombocytopenia
A Sardinian founder mutation in glycoprotein Ib platelet subunit beta (GP1BB) that impacts thrombocytopenia.
Thyroid Neoplasms
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Triple Negative Breast Neoplasms
Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy.
Uterine Cervical Neoplasms
MicroRNA-183-5p Inhibits Aggressiveness of Cervical Cancer Cells by Targeting Integrin Subunit Beta 1 (ITGB1).
Vaccinia
A yeast-based genetic system for functional analysis of viral mRNA capping enzymes.
Biochemical analysis of the multifunctional vaccinia mRNA capping enzyme encoded by a temperature sensitive virus mutant.
Catalytic activity of vaccinia mRNA capping enzyme subunits coexpressed in Escherichia coli.
Characterization of the vaccinia virus RNA 5'-triphosphatase and nucleotide triphosphate phosphohydrolase activities. Demonstrate that both activities are carried out at the same active site.
Complete nucleotide sequence of reovirus L2 gene and deduced amino acid sequence of viral mRNA guanylyltransferase.
Domain structure of the vaccinia virus mRNA capping enzyme. Expression in Escherichia coli of a subdomain possessing the RNA 5'-triphosphatase and guanylyltransferase activities and a kinetic comparison to the full-size enzyme.
Functional domains of vaccinia virus mRNA capping enzyme. Analysis by limited tryptic digestion.
Investigating Viruses during the Transformation of Molecular Biology.
Mapping the active site of vaccinia virus RNA triphosphatase.
Mapping the triphosphatase active site of baculovirus mRNA capping enzyme LEF4 and evidence for a two-metal mechanism.
Mechanism of mRNA capping by vaccinia virus guanylyltransferase: characterization of an enzyme--guanylate intermediate.
Methyltransferase and subunit association domains of vaccinia virus mRNA capping enzyme.
Modification of the 5' end of mRNA. Association of RNA triphosphatase with the RNA guanylyltransferase-RNA (guanine-7-)methyltransferase complex from vaccinia virus.
Mutational analysis of mRNA capping enzyme identifies amino acids involved in GTP binding, enzyme-guanylate formation, and GMP transfer to RNA.
Mutational analysis of the RNA triphosphatase component of vaccinia virus mRNA capping enzyme.
Phenotypic analysis of a temperature sensitive mutant in the large subunit of the vaccinia virus mRNA capping enzyme.
RNA 5'-triphosphatase, nucleoside triphosphatase, and guanylyltransferase activities of baculovirus LEF-4 protein.
Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl-transferase.
Structure of human PIR1, an atypical dual-specificity phosphatase.
The LEF-4 subunit of baculovirus RNA polymerase has RNA 5'-triphosphatase and ATPase activities.
The NS 3 nonstructural protein of flaviviruses contains an RNA triphosphatase activity.
Vaccinia virus gene D12L encodes the small subunit of the viral mRNA capping enzyme.
Vesicular Stomatitis
5'-Phospho-RNA Acceptor Specificity of GDP Polyribonucleotidyltransferase of Vesicular Stomatitis Virus in mRNA Capping.
Histidine-mediated RNA transfer to GDP for unique mRNA capping by vesicular stomatitis virus RNA polymerase.
Negative-Strand RNA Virus L Proteins: One Machine, Many Activities.
Signature motifs of GDP polyribonucleotidyltransferase, a non-segmented negative strand RNA viral mRNA capping enzyme, domain in the L protein are required for covalent enzyme-pRNA intermediate formation.
The large protein 'L' of Peste-des-petits-ruminants virus exhibits RNA triphosphatase activity, the first enzyme in mRNA capping pathway.
Unconventional mechanism of mRNA capping by the RNA-dependent RNA polymerase of vesicular stomatitis virus.
Vesicular stomatitis virus mRNA capping machinery requires specific cis-acting signals in the RNA.
[The multifunctional RNA polymerase L protein of non-segmented negative strand RNA viruses catalyzes unique mRNA capping].
Viremia
Alternate Capping Mechanisms for Transcription of Spring Viremia of Carp Virus: Evidence for Independent mRNA Initiation.
Virus Diseases
Proteasome subunit beta type-8 from sevenband grouper negatively regulates cytokine responses by interfering NF-?B signaling upon nervous necrosis viral infection.
RNA helicase DDX5 suppresses IFN-I antiviral innate immune response by interacting with PP2A-C? to deactivate IRF3.
Vitiligo
A case-control study on association of proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1) polymorphisms and their transcript levels in vitiligo from Gujarat.
Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma.
Yellow Fever
The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase.