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This enzyme hydrolyses the diphosphate bond, leaving a phospho group where a diphospho group had been. It can also act on bis(adenosine) diphosphate.
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The enzyme appears in viruses and cellular organisms
diphosphoinositol polyphosphate phosphohydrolase, dipp2, dipp3, mudipp1, diphosphoinositol phosphohydrolase, diphosphoinositol phosphate phosphohydrolase, diphosphoinositol-polyphosphate phosphohydrolase, aps protein, more
diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate