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Information on EC 3.6.1.22 - NAD+ diphosphatase

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EC Tree
     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.22 NAD+ diphosphatase
IUBMB Comments
This enzyme, described from plants, animals, and bacteria, can act on both reduced and oxidized forms of its substrate, although enzymes from different organisms have different preferences. Also acts on other dinucleotides, including NADP(H), FAD(H2), and the thionicotinamide analogues of NAD+ and NADP+.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
alkaline phosphodiesterase i, nadh pyrophosphatase, nad pyrophosphatase, nudx19, atnudx19, nad+ pyrophosphatase, nadph pyrophosphohydrolase, nudix hydrolase 19, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NAD(H) + H2O = AMP + NMN(H)
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NADH + H2O = AMP + NMNH
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