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Information on EC 3.6.1.12 - dCTP diphosphatase

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EC Tree
     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.12 dCTP diphosphatase
IUBMB Comments
The mammalian enzyme also displays weak activity against dTTP and dATP, but none against dGTP. Activity is highest with analogs including 5-iodo-dCTP and 5-methyl-dCTP.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
pyrophosphohydrolase, dctpp1, dctpase, rs21-c6, ntp pyrophosphohydrolase, dctp pyrophosphatase 1, dctpase-dutpase, ntp pyrophosphatase, xtp3-transactivated protein a, all-alpha ntp pyrophosphatase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dCTP + H2O = dCMP + diphosphate
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