Reference on EC 3.5.5.5 - Arylacetonitrilase
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Mauger, J.; Nagasawa, T.; Yamada, H.
Occurrence of a novel nitrilase, arylacetonitrilase, in Alcaligenes faecalis JM3
Arch. Microbiol.
155
1-6
1990
Alcaligenes faecalis, Alcaligenes faecalis JM3
-
Nagasawa, T.; Mauger, J.; Yamada, H.
A novel nitrilase, arylacetonitrilase, of Alcaligenes faecalis JM3. Purification and characterization
Eur. J. Biochem.
194
765-772
1990
Alcaligenes faecalis, Alcaligenes faecalis JM3
Layh, N.; Parratt, J.; Willetts, A.
Characterization and partial purification of an enantioselective arylacetonitrilase from Pseudomonas fluorescens DSM 7155
J. Mol. Catal. B
5
467-474
1998
Pseudomonas fluorescens
-
Banerjee, A.; Kaul, P.; Banerjee, U.C.
Purification and characterization of an enantioselective arylacetonitrilase from Pseudomonas putida
Arch. Microbiol.
184
407-418
2006
Pseudomonas putida
Kiziak, C.; Conradt, D.; Stolz, A.; Mattes, R.; Klein, J.
Nitrilase from Pseudomonas fluorescens EBC191: cloning and heterologous expression of the gene and biochemical characterization of the recombinant enzyme
Microbiology
151
3639-3648
2005
Pseudomonas fluorescens, Pseudomonas fluorescens EBC191
Rustler, S.; Motejadded, H.; Altenbuchner, J.; Stolz, A.
Simultaneous expression of an arylacetonitrilase from Pseudomonas fluorescens and a (S)-oxynitrilase from Manihot esculenta in Pichia pastoris for the synthesis of (S)-mandelic acid
Appl. Microbiol. Biotechnol.
80
87-97
2008
Pseudomonas fluorescens, Pseudomonas fluorescens EBC191
Zhu, D.; Mukherjee, C.; Yang, Y.; Rios, B.E.; Gallagher, D.T.; Smith, N.N.; Biehl, E.R.; Hua, L.
A new nitrilase from Bradyrhizobium japonicum USDA 110. Gene cloning, biochemical characterization and substrate specificity
J. Biotechnol.
133
327-333
2008
Bradyrhizobium japonicum, Bradyrhizobium japonicum USDA 110
Kiziak, C.; Klein, J.; Stolz, A.
Influence of different carboxy-terminal mutations on the substrate-, reaction- and enantiospecificity of the arylacetonitrilase from Pseudomonas fluorescens EBC191
Protein Eng. Des. Sel.
20
385-396
2007
Pseudomonas fluorescens, Pseudomonas fluorescens EBC191
Banerjee, A.; Dubey, S.; Kaul, P.; Barse, B.; Piotrowski, M.; Banerjee, U.C.
enantioselective nitrilase from Pseudomonas putida: cloning, heterologous expression, and bioreactor studies
Mol. Biotechnol.
41
35-41
2008
Pseudomonas putida (B0LAW4), Pseudomonas putida MTCC 5110 (B0LAW4)
Agerbirk, N.; Warwick, S.I.; Hansen, P.R.; Olsen, C.E.
Sinapis phylogeny and evolution of glucosinolates and specific nitrile degrading enzymes
Phytochemistry
69
2937-2949
2008
Sinapis alba
Rustler, S.; Chmura, A.; Sheldon, R.A.; Stolz, A.
Characterisation of the substrate specificity of the nitrile hydrolyzing system of the acidotolerant black yeast Exophiala oligosperma R1
Stud. Mycol.
61
165-174
2008
Exophiala oligosperma, Exophiala oligosperma R1
Kiziak, C.; Stolz, A.
Identification of amino acid residues responsible for the enantioselectivity and amide formation capacity of the arylacetonitrilase from Pseudomonas fluorescens EBC191
Appl. Environ. Microbiol.
75
5592-5599
2009
Pseudomonas fluorescens (Q5EG61), Pseudomonas fluorescens
Sosedov, O.; Baum, S.; Buerger, S.; Matzer, K.; Kiziak, C.; Stolz, A.
Construction and application of variants of the Pseudomonas fluorescens EBC191 arylacetonitrilase for increased production of acids or amides
Appl. Environ. Microbiol.
76
3668-3674
2010
Pseudomonas fluorescens
Thuku, R.; Brady, D.; Benedik, M.; Sewell, B.
Microbial nitrilases: Versatile, spiral forming, industrial enzymes
J. Appl. Microbiol.
106
703-727
2009
Alcaligenes faecalis, Alcaligenes faecalis ATCC 8750
He, Y.C.; Zhang, Z.J.; Xu, J.H.; Liu, Y.Y.
Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by cetyltrimethylammonium bromide-permeabilized cells of Alcaligenes faecalis ECU0401
J. Ind. Microbiol. Biotechnol.
37
741-750
2010
Alcaligenes faecalis
Howden, A.J.; Rico, A.; Mentlak, T.; Miguet, L.; Preston, G.M.
Pseudomonas syringae pv. syringae B728a hydrolyses indole-3-acetonitrile to the plant hormone indole-3-acetic acid
Mol. Plant Pathol.
10
857-865
2009
Pseudomonas syringae pv. syringae, no activity in no activity in Pseudomonas syringae pv. tomato, Pseudomonas syringae pv. syringae B728a
Sosedov, O.; Matzer, K.; Buerger, S.; Kiziak, C.; Baum, S.; Altenbuchner, J.; Chmura, A.; van Rantwijk, F.; Stolz, A.
Synthesis of enantiomerically pure (S)-mandelic acid using anoxynitrilasenitrilase bienzymatic cascade: a nitrilase surprisingly shows nitrile hydratase activity
Adv. Synth. Catal.
351
1531 - 1538
2009
Pseudomonas fluorescens (Q5EG61), Pseudomonas fluorescens EBC191 (Q5EG61)
-
Mateo, C.; Fernandes, B.; van Rantwijk, F.; Stolz, A.; Sheldon, R.A.
Stabilisation of oxygen-labile nitrilases via co-aggregation with poly(ethyleneimine)
J. Mol. Catal. B
38
154-157
2006
Pseudomonas fluorescens (Q5EG61), Pseudomonas fluorescens EBC191 (Q5EG61)
-
Mateo, C.; Chmura, A.; Rustler, S.; van Rantwijk, F.; Stolz, A.; Sheldon, R.A.
Synthesis of enantiomerically pure (S)-mandelic acid using anoxynitrilasenitrilase bienzymatic cascade: a nitrilase surprisingly shows nitrile hydratase activity
Tetrahedron Asymmetry
17
320-323
2006
Pseudomonas fluorescens (Q5EG61), Pseudomonas fluorescens EBC191 (Q5EG61)
-
Baum, S.; Williamson, D.S.; Sewell, T.; Stolz, A.
Conversion of sterically demanding alpha,alpha-disubstituted phenylacetonitriles by the arylacetonitrilase from Pseudomonas fluorescens EBC191
Appl. Environ. Microbiol.
78
48-57
2012
Pseudomonas fluorescens, Pseudomonas fluorescens EBC191
Petrickova, A.; Vesela, A.B.; Kaplan, O.; Kubac, D.; Uhnakova, B.; Malandra, A.; Felsberg, J.; Rinagelova, A.; Weyrauch, P.; K?en, V.; Bezouska, K.; Martinkova, L.
Purification and characterization of heterologously expressed nitrilases from filamentous fungi
Appl. Microbiol. Biotechnol.
93
1553-1561
2012
Neurospora crassa, Aspergillus niger (A2R6M7), Aspergillus niger (A9QXE0), Aspergillus niger CBS 513.88 (A2R6M7), Aspergillus niger CBS 513.88 (A9QXE0), Neurospora crassa OR74A
Detzel, C.; Maas, R.; Jose, J.
Autodisplay of nitrilase from Alcaligenes faecalis in E. coli yields a whole cell biocatalyst for the synthesis of enantiomerically pure (R)-mandelic Acid
ChemCatChem
3
719-725
2011
Alcaligenes faecalis, Alcaligenes faecalis ATCC 8750
-
Liu, Z.Q.; Dong, L.Z.; Cheng, F.; Xue, Y.P.; Wang, Y.S.; Ding, J.N.; Zheng, Y.G.; Shen, Y.C.
Gene cloning, expression, and characterization of a nitrilase from Alcaligenes faecalis ZJUTB10
J. Agric. Food Chem.
59
11560-11570
2011
Alcaligenes faecalis, Alcaligenes faecalis ZJUTB10
Sosedov, O.; Stolz, A.
Improvement of the amides forming capacity of the arylacetonitrilase from Pseudomonas fluorescens EBC191 by site-directed mutagenesis
Appl. Microbiol. Biotechnol.
99
2623-2635
2015
Pseudomonas fluorescens, Pseudomonas fluorescens EBC191
Bhatia, S.; Mehta, P.; Bhatia, R.; Bhalla, T.
Purification and characterization of arylacetonitrile-specific nitrilase of Alcaligenes sp. MTCC 10675
Biotechnol. Appl. Biochem.
61
459-465
2014
Alcaligenes sp. (L7RY40), Alcaligenes sp. MTCC 10675 (L7RY40)
Sun, H.; Gao, W.; Fan, H.; Wang, H.; Wei, D.
Cloning, purification and evaluation of the enzymatic properties of a novel arylacetonitrilase from Luminiphilus syltensis NOR5-1B: a potential biocatalyst for the synthesis of mandelic acid and its derivatives
Biotechnol. Lett.
37
1655-1661
2015
Luminiphilus syltensis, Luminiphilus syltensis NOR5-1B
Petrickova, A.; Sosedov, O.; Baum, S.; Stolz, A.; Martinkova, L.
Influence of point mutations near the active site on the catalytic properties of fungal arylacetonitrilases from Aspergillus niger and Neurospora crassa
J. Mol. Catal. B
77
74-80
2012
Aspergillus niger (A2R6M7), Neurospora crassa (V5IPE4), Neurospora crassa DSM 1257 (V5IPE4), Aspergillus niger CBS 513.88 (A2R6M7)
-
Vesela, A.B.; Rucka, L.; Kaplan, O.; Pelantova, H.; Ne?vera, J.; Patek, M.; Martinkova, L.
Bringing nitrilase sequences from databases to life the search for novel substrate specificities with a focus on dinitriles
Appl. Microbiol. Biotechnol.
100
2193-2202
2016
Auricularia delicata (A0A0P1DJE3), Aspergillus luchuensis (G7X8S6), Trichoderma virens Gv29-8 (G9N4E3), Macrophomina phaseolina (K2QXC4), Macrophomina phaseolina MS6 (K2QXC4), Auricularia delicata TFB-10046 SS5 (A0A0P1DJE3), Aspergillus luchuensis IFO 4308 (G7X8S6)
Eppinger, E.; Stolz, A.
Conversion of phenylglycinonitrile by recombinant Escherichia coli cells synthesizing variants of the arylacetonitrilase from Pseudomonas fluorescens EBC191
Appl. Microbiol. Biotechnol.
103
6737-6746
2019
Pseudomonas fluorescens (Q5EG61), Pseudomonas fluorescens EBC191 (Q5EG61), Pseudomonas fluorescens EBC191
Sun, H.; Wang, H.; Gao, W.; Chen, L.; Wu, K.; Wei, D.
Directed evolution of nitrilase PpL19 from Pseudomonas psychrotolerans L19 and identification of enantiocomplementary mutants toward mandelonitrile
Biochem. Biophys. Res. Commun.
468
820-825
2015
Pseudomonas psychrotolerans, Pseudomonas psychrotolerans L19
Sun, H.; Gao, W.; Wang, H.; Wei, D.
Expression, characterization of a novel nitrilase PpL19 from Pseudomonas psychrotolerans with S-selectivity toward mandelonitrile present in active inclusion bodies
Biotechnol. Lett.
38
455-461
2016
Pseudomonas psychrotolerans, Pseudomonas psychrotolerans L19
Vesela, A.; Krenkova, A.; Martinkova, L.
Exploring the potential of fungal arylacetonitrilases in mandelic acid synthesis
Mol. Biotechnol.
57
466-474
2015
Aspergillus niger
-
Thakur, N.; Kumar, V.; Thakur, S.; Sharma, N.; Sheeta, S.; Bhalla, T.
Biotransformation of 4-hydroxyphenylacetonitrile to 4-hydroxyphenylacetic acid using whole cell arylacetonitrilase of Alcaligenes faecalis MTCC 12629
Proc. Biochem.
73
117-123
2018
Alcaligenes faecalis, Alcaligenes faecalis MTCC 12629
-
Brunner, S.; Eppinger, E.; Fischer, S.; Groening, J.; Stolz, A.
Conversion of aliphatic nitriles by the arylacetonitrilase from Pseudomonas fluorescens EBC191
World J. Microbiol. Biotechnol.
34
91
2018
Pseudomonas fluorescens (Q5EG61), Pseudomonas fluorescens EBC191 (Q5EG61), Pseudomonas fluorescens EBC191
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