Reference on EC 3.5.4.3 - guanine deaminase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Negishi, O.; Ozawa, T.; Imagawa, H.
Guanosine deaminase and guanine deaminase from tea leaves
Biosci. Biotechnol. Biochem.
58
1277-1281
1994
Camellia sinensis, Clostridium sp., Nicotiana tabacum, Rattus norvegicus
-
Kimm, S.W.; Park, J.B.; Kim, H.L.
The physicochemical properties of guanine aminohydrolase purified from human liver
Korean J. Biochem.
19
39-46
1987
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus, Sus sp.
-
Kimm, S.W.; Park, J.B.; Lee, I.S.
Purification and characterization of guanine aminohydrolase from human liver
Korean J. Biochem.
17
139-148
1985
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus
-
Gupta, N.K.; Glantz, M.D.
Isolation and characterization of human liver guanine deaminase
Arch. Biochem. Biophys.
236
266-276
1985
Bos taurus, Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus, Sus sp.
Pugh, M.E.; Bieber, A.L.
Studies of rabbit brain, intestine and liver guanine aminohydrolase
Comp. Biochem. Physiol. B
77
619-627
1984
Bos taurus, Cavia porcellus, Oryctolagus cuniculus, Homo sapiens, Ovis ammon, Sus sp.
Kim, C.J.; Kimm, S.W.
Enzymatic evidence for a mitochondrial inhibitor of guanine aminohydrolase in rat liver
Korean J. Biochem.
14
77-93
1982
Clostridium sp., Homo sapiens, Mus musculus, Ophiodon elongatus, Rattus norvegicus, Rattus norvegicus Sprague Dawley
-
Miyamoto, S.; Ogawa, H.; Shiraki, H.; Nakagawa, H.
Guanine deaminase from rat brain. Purification, characteristics, and contribution to ammoniagenesis in the brain
J. Biochem.
91
167-176
1982
Rattus norvegicus, Rattus norvegicus Wistar, Sus sp.
Kuzmits, R.; Stemberger, H.; Muller, M.M.
Guanase from human liver - purification and characterization
Adv. Exp. Med. Biol.
122B
183-188
1980
Homo sapiens, Mus musculus, Rattus norvegicus
Bergstrom, J.D.; Bieber, A.L.
Characterization of purified guanine aminohydrolase
Arch. Biochem. Biophys.
194
107-116
1979
Oryctolagus cuniculus
Glantz, M.D.; Lewis, A.S.
Guanine deaminase from rabbit liver
Methods Enzymol.
51
512-517
1978
Oryctolagus cuniculus
Rossi, C.A.; Hakim, G.; Solaini, G.
Purification and properties of pig brain guanine deaminase
Biochim. Biophys. Acta
526
235-246
1978
Oryctolagus cuniculus, Platyrrhini, Mus musculus, Ovis ammon, Rattus norvegicus, Sus sp.
Fogle, P.J.; Bieber, A.L.
Purification of rabbit liver guanine aminohydrolase
Prep. Biochem.
5
59-77
1975
Oryctolagus cuniculus, Homo sapiens, Ophiodon elongatus, Rattus norvegicus
Lewis, A.S.; Glantz, M.D.
Rabbit liver guanine deaminase. Chemical, physical, and kinetic properties
J. Biol. Chem.
249
3862-3866
1974
Oryctolagus cuniculus, Rattus norvegicus
Kumar, K.S.; Sitaramayya, A.; Krishnan, P.S.
Guanine deaminase in rat liver and mouse liver and brain
Biochem. J.
128
1079-1088
1972
Mus musculus, Rattus norvegicus
Rabinowitz, J.C.; Barker, H.A.
Purine fermentation by Clostridium cylindrosporum
J. Biol. Chem.
218
161-173
1956
Clostridium sp.
Ito, S.; Maeda, T.; Iwasaki, A.; Fujikawa, H.; Okahisa, T.; Saijyou, T.; II, K.; Sano, N.; Matsuda, Y.; Endo, H.
Histochemical and biochemical studies on guanase in the human and rat kidney
Acta Histochem.
24
591-596
1991
Homo sapiens, Mus musculus, Rattus norvegicus
-
Canbolat, O.; Durak, I.; Cetin, R.; Kavutcu, M.; Demirci, S.; Oeztuerk, S.
Activities of adenosine deaminase, 5'-nucleotidase, guanase, and cytidine deaminase enzymes in cancerous and non-cancerous human breast tissues
Breast Cancer Res. Treat.
37
189-193
1996
Homo sapiens
Rajappan, V.P.; Hosmane, R.
Analogues of azepinomycin as inhibitors of guanase
Nucleosides Nucleotides
17
1141-1151
1998
Oryctolagus cuniculus, Homo sapiens
Yuan, G.; Bin, J.C.; McKay, D.J.; Snyder, F.F.
Cloning and characterization of human guanine deaminase. Purification and partial amino acid sequence of the mouse protein
J. Biol. Chem.
274
8175-8180
1999
Mus musculus, Sus sp., Homo sapiens (Q9Y2T3), Homo sapiens
Maynes, J.T.; Yuan, R.G.; Snyder, F.F.
Identification, expression and characterization of Escherichia coli guanine deaminase
J. Bacteriol.
8
4658-4660
2000
Escherichia coli, Homo sapiens (Q9Y2T3), Homo sapiens
Liaw, S.H.; Chang, Y.J.; Lai, C.T.; Chang, H.C.; Chang, G.G.
Crystal structure of Bacillus subtilis guanine deaminase: the first domain-swapped structure in the cytidine deaminase superfamily
J. Biol. Chem.
279
35479-35485
2004
Bacillus subtilis (O34598), Bacillus subtilis
Chang Yu Ju, C.Y.; Huang Chun Hsian, H.C.; Hu Chih Yun, H.C.; Liaw Shwu Hue, L.S.
Crystallization and preliminary crystallographic analysis of Bacillus subtilis guanine deaminase
Acta Crystallogr. Sect. D
60
1152-1154
2004
Bacillus subtilis
Roberts, E.L.; Newton, R.P.
Estimation of guanine deaminase using guanosine as a "prosubstrate"
Anal. Biochem.
324
250-257
2004
Homo sapiens
Ujjinamatada, R.K.; Bhan, A.; Hosmane, R.S.
Design of inhibitors against guanase: Synthesis and biochemical evaluation of analogues of azepinomycin
Bioorg. Med. Chem. Lett.
16
5551-5554
2006
Oryctolagus cuniculus
Saint-Marc, C.; Daignan-Fornier, B.
GUD1 (YDL238c) encodes Saccharomyces cerevisiae guanine deaminase, an enzyme expressed during post-diauxic growth
Yeast
21
1359-1363
2004
Saccharomyces cerevisiae
Sannomiya, K.; Honda, H.; Kubo, K.; Ii, K.; Yuan, Y.; Aoyagi, E.; Muguruma, N.; Shimizu, I.; Ito, S.
A histochemical and immunohistochemical investigation of guanase and nedasin in rat and human tissues
J. Med. Invest.
53
246-254
2006
Homo sapiens, Rattus norvegicus
Kubo, K.; Honda, H.; Honda, H.; Sannomiya, K.; Aying, Y.; Mei, W.; Mi, S.; Aoyagi, E.; Simizu, I.; Ii, K.; Ito, S.
Histochemical and immunohistochemical investigation of guanase and nedasin in human tissues
J. Med. Invest.
53
264-270
2006
Homo sapiens
Yao, L.; Cukier, R.I.; Yan, H.
Catalytic mechanism of guanine deaminase: an ONIOM and molecular dynamics study
J. Phys. Chem. B
111
4200-4210
2007
Bacillus subtilis
Fernandez, J.R.; Welsh, W.J.; Firestein, B.L.
Structural characterization of the zinc binding domain in cytosolic PSD-95 interactor (cypin): Role of zinc binding in guanine deamination and dendrite branching
Proteins
70
873-881
2008
Rattus norvegicus
Medici, R.; Lewkowicz, E.S.; Iribarren, A.M.
Arthrobacter oxydans as a biocatalyst for purine deamination
FEMS Microbiol. Lett.
289
20-26
2008
Pseudarthrobacter oxydans
Fernandez, J.R.; Sweet, E.S.; Welsh, W.J.; Firestein, B.L.
Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine
Bioorg. Med. Chem.
18
6748-6755
2010
Oryctolagus cuniculus, Rattus norvegicus, Homo sapiens (Q9Y2T3), Homo sapiens
Seffernick, J.L.; Dodge, A.G.; Sadowsky, M.J.; Bumpus, J.A.; Wackett, L.P.
Bacterial ammeline metabolism via guanine deaminase
J. Bacteriol.
192
1106-1112
2010
Bradyrhizobium japonicum, Bradyrhizobium japonicum USDA 110, Escherichia coli, Homo sapiens (Q9Y2T3), Pseudomonas putida, Pseudomonas putida KT 2240
Kim, J.; Park, S.I.; Ahn, C.; Kim, H.; Yim, J.
Guanine deaminase functions as dihydropterin deaminase in the biosynthesis of aurodrosopterin, a minor red eye pigment of Drosophila
J. Biol. Chem.
284
23426-23435
2009
Drosophila melanogaster, Drosophila melanogaster Oregon-R
Murphy, P.M.; Bolduc, J.M.; Gallaher, J.L.; Stoddard, B.L.; Baker, D.
Alteration of enzyme specificity by computational loop remodeling and design
Proc. Natl. Acad. Sci. USA
106
9215-9220
2009
Homo sapiens (Q9Y2T3), Homo sapiens
Guzman, K.; Badia, J.; Gimenez, R.; Aguilar, J.; Baldoma, L.
Transcriptional regulation of the gene cluster encoding allantoinase and guanine deaminase in Klebsiella pneumoniae
J. Bacteriol.
193
2197-2207
2011
Klebsiella pneumoniae
Bitra, A.; Hussain, B.; Tanwar, A.S.; Anand, R.
Identification of function and mechanistic insights of guanine deaminase from Nitrosomonas europaea: role of the C-terminal loop in catalysis
Biochemistry
52
3512-3522
2013
Nitrosomonas europaea (Q82Y41), Nitrosomonas europaea
Chakraborty, S.; Shah, N.H.; Fishbein, J.C.; Hosmane, R.S.
Investigations into specificity of azepinomycin for inhibition of guanase: discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues
Bioorg. Med. Chem. Lett.
22
7214-7218
2012
Oryctolagus cuniculus
Tantravedi, S.; Chakraborty, S.; Shah, N.H.; Fishbein, J.C.; Hosmane, R.S.
Analogs of iso-azepinomycin as potential transition-state analog inhibitors of guanase: synthesis, biochemical screening, and structure-activity correlations of various selectively substituted imidazo[4,5-e][1,4]diazepines
Bioorg. Med. Chem.
21
4893-4903
2013
Oryctolagus cuniculus
Stuer-Lauridsen, B.; Nygaard, P.
Purine salvage in two halophilic archaea: characterization of salvage pathways and isolation of mutants resistant to purine analogs
J. Bacteriol.
180
457-463
1998
Halobacterium salinarum, Haloferax volcanii
Trautwein-Schult, A.; Jankowska, D.; Cordes, A.; Hoferichter, P.; Klein, C.; Matros, A.; Mock, H.P.; Baronian, K.; Bode, R.; Kunze, G.
Arxula adeninivorans recombinant guanine deaminase and its application in the production of food with low purine content
J. Mol. Microbiol. Biotechnol.
24
67-81
2014
Blastobotrys adeninivorans, Blastobotrys adeninivorans LS3
Shek, R.; Hilaire, T.; Sim, J.; French, J.B.
Structural determinants for substrate selectivity in guanine deaminase enzymes of the amidohydrolase superfamily
Biochemistry
58
3280-3292
2019
Escherichia coli (P76641), Escherichia coli, Saccharomyces cerevisiae (Q07729), Saccharomyces cerevisiae
Slater, P.G.; Cammarata, G.M.; Monahan, C.; Bowers, J.T.; Yan, O.; Lee, S.; Lowery, L.A.
Characterization of Xenopus laevis guanine deaminase reveals new insights for its expression and function in the embryonic kidney
Dev. Dyn.
248
296-305
2019
Xenopus laevis
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