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Anaphylaxis
[Changes in the guanase activity in the lungs and blood serum of guinea pigs in anaphylactic shock]
Anemia
Guanase in reticulocytes and other rat tissues.
Balkan Nephropathy
Guanase activity in endemic Balkan nephropathy.
Brain Injuries
Cypin: A novel target for traumatic brain injury.
Brain Injuries, Traumatic
Cypin: A novel target for traumatic brain injury.
Carcinoma
Clinical evaluation of serum guanase activity in liver diseases.
Carcinoma, Hepatocellular
Clinical evaluation of serum guanase activity in liver diseases.
Carcinoma, Hepatocellular
Clinical significance of serum guanase activity in various liver diseases.
Carcinoma, Hepatocellular
Estimation of guanine deaminase using guanosine as a "prosubstrate".
Diabetes Mellitus, Experimental
[Characteristics of purine and nucleotide metabolism in juvenile rats with alloxan diabetes]
Fatty Liver
Evaluation of serum guanase in hepatic diseases.
Glomerulonephritis
[Guanine deaminase and adenosine deaminase activity in chronic glomerulonephritis]
Gout
Effects of plumbous ion on guanine metabolism.
Heart Failure
Clinical and experimental studies of the determination of serum guanase activity in acute myocardial infarction.
Hepatitis
A sensitive spectrophotometric assay for guanase activity.
Hepatitis
Clinical evaluation of serum guanase activity in liver diseases.
Hepatitis
Clinical significance of serum guanase activity in various liver diseases.
Hepatitis
Clinical value of the guanase screening test in donor blood for prevention of posttransfusional non-A, non-B hepatitis.
Hepatitis
Cytochemical demonstration of guanase in human liver using yellow tetrazolium.
Hepatitis
Evaluation of serum guanase in hepatic diseases.
Hepatitis
Guanase activity in the donor serum and the incidence of posttransfusion hepatitis non-A, non-B.
Hepatitis
Prevention of posttransfusional non-A, non-B hepatitis using the screening test for guanase activity of donor blood.
Hepatitis
Relationship between guanase activity in donor blood and the incidence of posttransfusional non-A, non-B hepatitis, and a possible method for preventing posttransfusional hepatitis.
Hepatitis
Serum guanase activity in viral hepatitis and some other hepatic and extrahepatic diseases.
Hepatitis
[Activity of cobalt-activated acylase and guanase in the serum of patients with viral hepatitis]
Hepatitis
[Experiences and significance of the determination of guanase in acute hepatitis]
Hepatitis
[Guanase activity of human blood in viral hepatitis and other liver diseases]
Hepatitis
[Measurement of serum guanase activity and prevention of non-A, non-B hepatitis]
Hepatitis
[Screening of the donor's blood by measuring the serum guanase level for the prevention of posttransfusion hepatitis in cardiac surgery]
Hepatitis
[Studies on the diagnostic value of various enzymatic activties in icterogenic hepatitis of infancy. II. Sorbitol dehydrogenase, guanase and argininosuccinate lyase]
Hepatitis
[The prevention of post-transfusional hepatitis using measurement of guanase activity]
Hepatitis
[The relationship between the guanase activity of donor and incidence of posttransfusion hepatitis]
Hepatitis A
[Determination of guanine deaminase activity in infectious hepatitis]
Hepatitis C
Clinical value of the determination of serum guanase activity in patients with chronic hepatitis type C.
Hepatitis C
Estimation of guanine deaminase using guanosine as a "prosubstrate".
Hepatitis C
Serum guanase activity in hepatitis C virus infection.
Hepatitis, Chronic
Clinical evaluation of serum guanase activity in liver diseases.
Hepatitis, Chronic
Clinical significance of serum guanase activity in various liver diseases.
Hepatitis, Chronic
Clinical value of the determination of serum guanase activity in patients with chronic hepatitis type C.
Hepatitis, Chronic
Evaluation of serum guanase in hepatic diseases.
Hepatitis, Chronic
[Activity of guanase in serum and liver function tests in HBe antigen-positive chronic hepatitis]
Herpes Zoster
A novel role for snapin in dendrite patterning: interaction with cypin.
Infections
Purine pathway enzymes in a cyst forming strain of Toxoplasma gondii.
Intellectual Disability
Deficiency of a naturally occurring protein inhibitor in brain of clinically 'brain damaged' newborn human infants - A possible cause of mental retardation?
Keratosis
Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites.
Kidney Diseases
Serum guanase in kidney diseases.
Leukemia
Value of ribonuclease and guanase activity for the diagnosis of leukemias.
Liver Cirrhosis
Clinical evaluation of serum guanase activity in liver diseases.
Liver Cirrhosis
Clinical significance of serum guanase activity in various liver diseases.
Liver Cirrhosis
Evaluation of serum guanase in hepatic diseases.
Liver Cirrhosis, Alcoholic
Histochemical demonstration of guanase in human liver with guanine in bicine buffer as substrate.
Liver Cirrhosis, Biliary
Histochemical demonstration of guanase in human liver with guanine in bicine buffer as substrate.
Liver Diseases
A simple and sensitive radiochemical assay for plasma guanase.
Liver Diseases
Clinical evaluation of serum guanase activity in liver diseases.
Liver Diseases
Clinical significance of serum guanase activity in various liver diseases.
Liver Diseases
Determination of guanase activity in normal and pathological sera by high-performance liquid chromatography.
Liver Diseases
Enzymological aspects of disorders in purine metabolism.
Liver Diseases
Evaluation of the spectrophotometric assay of guanase with 2,2'-azino-di(3-ethylbenzthiazoline-6-sulphonate) (ABTS) as chromogen.
Liver Diseases
Guanase activity in the donor serum and the incidence of posttransfusion hepatitis non-A, non-B.
Liver Diseases
Serum guanase in diagnosis of liver disease.
Liver Diseases
[Activity of guanase and ornithine carbamyl transferase in blood serum of patients with liver disease]
Liver Diseases
[Clinical and laboratory-based evaluation of serum guanase activity in liver diseases]
Liver Diseases
[Clinical values of guanase activity in liver disease]
Liver Diseases
[Guanase activity of human blood in viral hepatitis and other liver diseases]
Liver Diseases
[Serum guanase in liver diseases]
Liver Diseases
[The value of the determinations of guanase and ornithine carbamyl-transferase activities in diagnosis of liver diseases]
Liver Diseases, Alcoholic
Clinical value of serum guanase in alcoholic liver disease.
Lung Neoplasms
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
Melanosis
Guanine Deaminase in Human Epidermal Keratinocytes Contributes to Skin Pigmentation.
Multiple Sclerosis
[Clinical significance of CSF guanase activity in patient with multiple sclerosis]
Multiple Sclerosis
[Determination of CSF guanase activity in multiple sclerosis: a comparative study on various parameters to monitor the disease activity]
Myocardial Infarction
Clinical and experimental studies of the determination of serum guanase activity in acute myocardial infarction.
Myocardial Infarction
Clinical evaluation of measurement of serum guanase activity as a screening test of liver damage.
Myocardial Infarction
Clinical value of the determination of serum guanase activity in acute myocardial infarction.
Myocardial Infarction
Clinical value of the determination of serum guanase activity. Studies on patients and experimental data from mongrel dogs and cultured rat hepatocytes.
Myocardial Infarction
Serum guanase activities after myocardial infarction.
Neoplasms
Analogs of iso-azepinomycin as potential transition-state analog inhibitors of guanase: synthesis, biochemical screening, and structure-activity correlations of various selectively substituted imidazo[4,5-e][1,4]diazepines.
Neoplasms
Enzymes and cancer. Preparation and some properties of guanase from rabbit liver.
Neoplasms
Markers of squamocolumnar junction cells in normal tonsils and oropharyngeal cancer with and without HPV infection.
Neoplasms
Short anogenital distance is associated with testicular germ cell tumour development.
Neoplasms
Uridine kinase, adenylate kinase, and guanase in human lung tumors.
Neoplasms, Germ Cell and Embryonal
Short anogenital distance is associated with testicular germ cell tumour development.
Neuroblastoma
A comparison of purine metabolism and nucleotide pools in normal and hypoxanthine-guanine phosphoribosyltransferase-deficient neuroblastoma cells.
Obesity
Target identification of the novel antiobesity agent tungstate in adipose tissue from obese rats.
Papillomavirus Infections
Markers of squamocolumnar junction cells in normal tonsils and oropharyngeal cancer with and without HPV infection.
Premature Ejaculation
The relationship between anogenital distance and lifelong premature ejaculation.
Prostatic Neoplasms
Assesment of anogenital distance as a marker in diagnosis of prostate cancer.
Starvation
Guanine deaminase in the developing rat brain: effect of starvation.
Stomach Neoplasms
Adenosine deaminase, 5'-nucleotidase, guanase and cytidine deaminase activities in gastric tissues from patients with gastric cancer.
Virus Diseases
Serum guanase activity in hepatitis C virus infection.
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Kimm, S.W.; Park, J.B.; Kim, H.L.
The physicochemical properties of guanine aminohydrolase purified from human liver
Korean J. Biochem.
19
39-46
1987
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus, Sus sp.
-
brenda
Kimm, S.W.; Park, J.B.; Lee, I.S.
Purification and characterization of guanine aminohydrolase from human liver
Korean J. Biochem.
17
139-148
1985
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus
-
brenda
Gupta, N.K.; Glantz, M.D.
Isolation and characterization of human liver guanine deaminase
Arch. Biochem. Biophys.
236
266-276
1985
Bos taurus, Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus, Sus sp.
brenda
Pugh, M.E.; Bieber, A.L.
Studies of rabbit brain, intestine and liver guanine aminohydrolase
Comp. Biochem. Physiol. B
77
619-627
1984
Bos taurus, Cavia porcellus, Oryctolagus cuniculus, Homo sapiens, Ovis ammon, Sus sp.
brenda
Kim, C.J.; Kimm, S.W.
Enzymatic evidence for a mitochondrial inhibitor of guanine aminohydrolase in rat liver
Korean J. Biochem.
14
77-93
1982
Clostridium sp., Homo sapiens, Mus musculus, Ophiodon elongatus, Rattus norvegicus, Rattus norvegicus Sprague Dawley
-
brenda
Kuzmits, R.; Stemberger, H.; Muller, M.M.
Guanase from human liver - purification and characterization
Adv. Exp. Med. Biol.
122B
183-188
1980
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Fogle, P.J.; Bieber, A.L.
Purification of rabbit liver guanine aminohydrolase
Prep. Biochem.
5
59-77
1975
Oryctolagus cuniculus, Homo sapiens, Ophiodon elongatus, Rattus norvegicus
brenda
Ito, S.; Maeda, T.; Iwasaki, A.; Fujikawa, H.; Okahisa, T.; Saijyou, T.; II, K.; Sano, N.; Matsuda, Y.; Endo, H.
Histochemical and biochemical studies on guanase in the human and rat kidney
Acta Histochem.
24
591-596
1991
Homo sapiens, Mus musculus, Rattus norvegicus
-
brenda
Canbolat, O.; Durak, I.; Cetin, R.; Kavutcu, M.; Demirci, S.; Oeztuerk, S.
Activities of adenosine deaminase, 5'-nucleotidase, guanase, and cytidine deaminase enzymes in cancerous and non-cancerous human breast tissues
Breast Cancer Res. Treat.
37
189-193
1996
Homo sapiens
brenda
Rajappan, V.P.; Hosmane, R.
Analogues of azepinomycin as inhibitors of guanase
Nucleosides Nucleotides
17
1141-1151
1998
Oryctolagus cuniculus, Homo sapiens
brenda
Yuan, G.; Bin, J.C.; McKay, D.J.; Snyder, F.F.
Cloning and characterization of human guanine deaminase. Purification and partial amino acid sequence of the mouse protein
J. Biol. Chem.
274
8175-8180
1999
Mus musculus, Sus sp., Homo sapiens (Q9Y2T3), Homo sapiens
brenda
Maynes, J.T.; Yuan, R.G.; Snyder, F.F.
Identification, expression and characterization of Escherichia coli guanine deaminase
J. Bacteriol.
8
4658-4660
2000
Escherichia coli, Homo sapiens (Q9Y2T3), Homo sapiens
brenda
Roberts, E.L.; Newton, R.P.
Estimation of guanine deaminase using guanosine as a "prosubstrate"
Anal. Biochem.
324
250-257
2004
Homo sapiens
brenda
Sannomiya, K.; Honda, H.; Kubo, K.; Ii, K.; Yuan, Y.; Aoyagi, E.; Muguruma, N.; Shimizu, I.; Ito, S.
A histochemical and immunohistochemical investigation of guanase and nedasin in rat and human tissues
J. Med. Invest.
53
246-254
2006
Homo sapiens, Rattus norvegicus
brenda
Kubo, K.; Honda, H.; Honda, H.; Sannomiya, K.; Aying, Y.; Mei, W.; Mi, S.; Aoyagi, E.; Simizu, I.; Ii, K.; Ito, S.
Histochemical and immunohistochemical investigation of guanase and nedasin in human tissues
J. Med. Invest.
53
264-270
2006
Homo sapiens
brenda
Fernandez, J.R.; Sweet, E.S.; Welsh, W.J.; Firestein, B.L.
Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine
Bioorg. Med. Chem.
18
6748-6755
2010
Oryctolagus cuniculus, Rattus norvegicus, Homo sapiens (Q9Y2T3), Homo sapiens
brenda
Seffernick, J.L.; Dodge, A.G.; Sadowsky, M.J.; Bumpus, J.A.; Wackett, L.P.
Bacterial ammeline metabolism via guanine deaminase
J. Bacteriol.
192
1106-1112
2010
Bradyrhizobium japonicum, Bradyrhizobium japonicum USDA 110, Escherichia coli, Homo sapiens (Q9Y2T3), Pseudomonas putida, Pseudomonas putida KT 2240
brenda
Murphy, P.M.; Bolduc, J.M.; Gallaher, J.L.; Stoddard, B.L.; Baker, D.
Alteration of enzyme specificity by computational loop remodeling and design
Proc. Natl. Acad. Sci. USA
106
9215-9220
2009
Homo sapiens (Q9Y2T3), Homo sapiens
brenda