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Information on EC 3.5.2.9 - 5-oxoprolinase (ATP-hydrolysing) and Organism(s) Bos taurus and UniProt Accession Q75WB5

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Bos taurus
UNIPROT: Q75WB5 not found.
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The taxonomic range for the selected organisms is: Bos taurus
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
5-oxoprolinase, 5-opase, oplah, 5-oxo-l-prolinase, opase, oxoprolinase, fgoxp1, fgoxp2, atp-dependent 5-oxoprolinase, prokaryotic 5-oxoprolinase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5-OPase
-
-
-
-
5-oxo-L-prolinase
-
-
-
-
5-oxoprolinase
-
-
-
-
L-pyroglutamate hydrolase
-
-
-
-
oxoprolinase
-
-
-
-
pyroglutamase
-
-
-
-
pyroglutamase (ATP-hydrolysing)
-
-
-
-
pyroglutamate hydrolase
-
-
-
-
pyroglutamic hydrolase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
carboxylic acid amide hydrolysis
-
-
-
-
PATHWAY SOURCE
PATHWAYS
-
-, -
SYSTEMATIC NAME
IUBMB Comments
5-oxo-L-proline amidohydrolase (ATP-hydrolysing)
-
CAS REGISTRY NUMBER
COMMENTARY hide
9075-46-1
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
5-oxo-L-proline + H2O + ATP
L-glutamate + ADP + phosphate
show the reaction diagram
-
-
-
?
5-oxo-L-proline + H2O + ATP
L-glutamate + ADP + phosphate
show the reaction diagram
-
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
5-oxo-L-proline + H2O + ATP
L-glutamate + ADP + phosphate
show the reaction diagram
-
-
-
-
?
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00195
cytosolic fraction of kidney
0.625
after purification by Sepharyl S-300, Blue Sepharose and Phenyl Sepharose column chromatography
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
Uniprot
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
-
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
OPLA_BOVIN
1288
0
137450
Swiss-Prot
other Location (Reliability: 3)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
150000
SDS-PAGE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Sepharyl S-300 gel filtration, Blue Sepharose and Phenyl Sepharose column chromatography
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Van Der Werf, P.; Griffith, O.W.; Meister, A.
5-Oxo-L-prolinase (L-pyroglutamate hydrolase) purification and catalytic properties
J. Biol. Chem.
250
6686-6692
1975
Bos taurus, Canis lupus familiaris, Felis catus, Mus musculus, Oryctolagus cuniculus, Ovis aries, Rattus norvegicus, Rattus norvegicus Sprague-Dawley, Sus scrofa
Manually annotated by BRENDA team
Watanabe, T.; Abe, K.; Ishikawa, H.; Iijima, Y.
Bovine 5-oxo-L-prolinase: simple assay method, purification, cDNA cloning, and detection of mRNA in the coronary artery
Biol. Pharm. Bull.
27
288-294
2004
Bos taurus (Q75WB5), Bos taurus
Manually annotated by BRENDA team