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Information on EC 3.5.2.17 - hydroxyisourate hydrolase and Organism(s) Escherichia coli and UniProt Accession P76341

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IUBMB Comments
The reaction is the first stage in the conversion of 5-hydroxyisourate into S-allantoin. This reaction will also occur spontaneously but more slowly.
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This record set is specific for:
Escherichia coli
UNIPROT: P76341
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Word Map
The taxonomic range for the selected organisms is: Escherichia coli
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
transthyretin, transthyretin-like protein, hydroxyisourate hydrolase, hiuhase, 5-hydroxyisourate hydrolase, transthyretin-related protein, hiu hydrolase, hiuase, sbttr, ectrp, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
transthyretin-related protein
-
5-hydroxyisourate hydrolase
-
-
-
-
HIUHase
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
5-hydroxyisourate amidohydrolase
The reaction is the first stage in the conversion of 5-hydroxyisourate into S-allantoin. This reaction will also occur spontaneously but more slowly.
CAS REGISTRY NUMBER
COMMENTARY hide
255885-20-2
-
pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8.2
estimated value
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
Uniprot
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
at pH 2-12
-
Manually annotated by BRENDA team
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3
below 3.0 separation into monomeric units
697901
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
66.7
melting temperature, below 66.7°C structure stable
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lundberg, E.; Olofsson, A.; Westermark, G.T.; Sauer-Eriksson, A.E.
Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein
FEBS J.
276
1999-2011
2009
Homo sapiens, Chilotilapia rhoadesii, Escherichia coli (P76341), Escherichia coli
Manually annotated by BRENDA team