Information on EC 3.5.1.95 - N-malonylurea hydrolase

for references in articles please use BRENDA:EC3.5.1.95
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The expected taxonomic range for this enzyme is: Rhodococcus erythropolis

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EC NUMBER
COMMENTARY hide
3.5.1.95
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RECOMMENDED NAME
GeneOntology No.
N-malonylurea hydrolase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-oxo-3-ureidopropanoate + H2O = malonate + urea
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
uracil degradation II (oxidative)
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Pyrimidine metabolism
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SYSTEMATIC NAME
IUBMB Comments
3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming)
Forms part of the oxidative pyrimidine-degrading pathway in some microorganisms, along with EC 1.17.99.4 (uracil/thymine dehydrogenase) and EC 3.5.2.1 (barbiturase).
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CAS REGISTRY NUMBER
COMMENTARY hide
368888-22-6
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ureidomalonic acid + H2O
malonate + urea
show the reaction diagram
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ureidomalonic acid + H2O
malonate + urea
show the reaction diagram
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli
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LINKS TO OTHER DATABASES (specific for EC-Number 3.5.1.95)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)