Reference on EC 3.5.1.92 - pantetheine hydrolase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dupre, S.; Chiaraluce, R.; Nardini, M.; Cannella, C.; Ricci, G.; Cavallini, D.
Continuous spectrophotometric assay of pantetheinase activity
Anal. Biochem.
142
175-181
1984
Equus caballus
Ricci, G.; Nardini, M.; Chiaraluce, R.; Dupre, S.; Cavallini, D.
Interaction of pantetheinase with sulfhydryl reagents and disulfides
Biochim. Biophys. Acta
870
82-91
1986
Sus scrofa
Pitari, G.; Maurizi, G.; Ascenzi, P.; Ricci, G.; Dupre, S.
A kinetic study on pantetheinase inhibition by disulfides
Eur. J. Biochem.
226
81-86
1994
Sus scrofa
Maras, B.; Barra, D.; Dupre, S.; Pitari, G.
Is pantetheinase the actual identity of mouse and human vanin-1 proteins?
FEBS Lett.
461
149-152
1999
Mus musculus, Sus scrofa
Pitari, G.; Malergue, F.; Martin, F.; Philippe, J.M.; Massucci, M.T.; Chabret, C.; Maras, B.; Dupre, S.; Naquet, P.; Galland, F.
Pantetheinase activity of membrane-bound vanin-1: lack of free cysteamine in tissues of vanin-1 deficient mice
FEBS Lett.
483
149-154
2000
Mus musculus
Bowles, J.; Bullejos, M.; Koopman, P.
A subtractive gene expression screen suggests a role for vanin-1 in testis development in mice
Genesis
27
124-135
2000
Mus musculus
Aurrand-Lions, M.; Galland, F.; Bazin, H.; Zakharyev, V.M.; Imhof, B.A.; Naquet, P.
Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing
Immunity
5
391-405
1996
Mus musculus
Martin, F.; Malergue, F.; Pitari, G.; Philippe, J.M.; Philips, S.; Chabret, C.; Granjeaud, S.; Mattei, M.G.; Mungall, A.J.; Naquet, P.; Galland, F.
Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes
Immunogenetics
53
296-306
2001
Mus musculus
Wittwer, C.T.; Burkhard, D.; Ririe, K.; Rasmussen, R.; Brown, J.; Wyse, B.W.; Hansen, R.G.
Purification and properties of a pantetheine-hydrolyzing enzyme from pig kidney
J. Biol. Chem.
258
9733-9738
1983
Sus scrofa
Wilson, M.J.; Jeyasuria, P.; Parker, K.L.; Koopman, P.
The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development
J. Biol. Chem.
280
5917-5923
2005
Mus musculus
Martin, F.; Penet, M.F.; Malergue, F.; Lepidi, H.; Dessein, A.; Galland, F.; de Reggi, M.; Naquet, P.; Gharib, B.
Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores
J. Clin. Invest.
113
591-597
2004
Mus musculus
Calvino, J.A.; Barcia, R.
Purification and properties of pantetheinase from pig kidney
J. Food Biochem.
26
103-118
2002
Sus scrofa
Wittwer, C.T.; Wyse, B.W.; Hansen, R.G.
Enzymic hydrolysis of pantetheine
Methods Enzymol.
122
36-43
1986
Sus scrofa
Dupre, S.; Cavallini, D.
Purification and properties of pantetheinase from horse kidney
Methods Enzymol.
62
262-267
1979
Equus caballus
Berruyer, C.; Martin, F.M.; Castellano, R.; Macone, A.; Malergue, F.; Garrido-Urbani, S.; Millet, V.; Imbert, J.; Dupre, S.; Pitari, G.; Naquet, P.; Galland, F.
Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress
Mol. Cell. Biol.
24
7214-7224
2004
Mus musculus
Johnson, K.A.; Yao, W.; Lane, N.E.; Naquet, P.; Terkeltaub, R.A.
Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank mice
Am. J. Pathol.
172
440-453
2008
Mus musculus
Roisin-Bouffay, C.; Castellano, R.; Valero, R.; Chasson, L.; Galland, F.; Naquet, P.
Mouse vanin-1 is cytoprotective for islet beta cells and regulates the development of type 1 diabetes
Diabetologia
51
1192-1201
2008
Mus musculus
Meghari, S.; Berruyer, C.; Lepidi, H.; Galland, F.; Naquet, P.; Mege, J.L.
Vanin-1 controls granuloma formation and macrophage polarization in Coxiella burnetii infection
Eur. J. Immunol.
37
24-32
2007
Mus musculus
Berruyer, C.; Pouyet, L.; Millet, V.; Martin, F.M.; LeGoffic, A.; Canonici, A.; Garcia, S.; Bagnis, C.; Naquet, P.; Galland, F.
Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity
J. Exp. Med.
203
2817-2827
2006
Mus musculus
Nitto, T.; Inoue, T.; Node, K.
Alternative spliced variants in the pantetheinase family of genes expressed in human neutrophils
Gene
426
57-64
2008
Homo sapiens (O95497), Homo sapiens (O95498), Homo sapiens (Q9NY84), Homo sapiens
Jansen, P.A.; Kamsteeg, M.; Rodijk-Olthuis, D.; van Vlijmen-Willems, I.M.; de Jongh, G.J.; Bergers, M.; Tjabringa, G.S.; Zeeuwen, P.L.; Schalkwijk, J.
Expression of the Vanin Gene Family in Normal and Inflamed Human Skin: Induction by Proinflammatory Cytokines
J. Invest. Dermatol.
129
2167-2174
2009
Homo sapiens (O95497), Homo sapiens (O95498), Homo sapiens (Q9NY84), Homo sapiens
Ruan, B.H.; Cole, D.C.; Wu, P.; Quazi, A.; Page, K.; Wright, J.F.; Huang, N.; Stock, J.R.; Nocka, K.; Aulabaugh, A.; Krykbaev, R.; Fitz, L.J.; Wolfman, N.M.; Fleming, M.L.
A fluorescent assay suitable for inhibitor screening and vanin tissue quantification
Anal. Biochem.
399
284-292
2010
Homo sapiens, Mus musculus
Kaskow, B.J.; Michael Proffit, J.; Blangero, J.; Moses, E.K.; Abraham, L.J.
Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases
Biochem. Biophys. Res. Commun.
417
653-658
2012
Homo sapiens, Mus musculus
Zhang, B.; Lo, C.; Shen, L.; Sood, R.; Jones, C.; Cusmano-Ozog, K.; Park-Snyder, S.; Wong, W.; Jeng, M.; Cowan, T.; Engleman, E.G.; Zehnder, J.L.
The role of vanin-1 and oxidative stress-related pathways in distinguishing acute and chronic pediatric ITP
Blood
117
4569-4579
2011
Homo sapiens
Hosohata, K.; Ando, H.; Fujiwara, Y.; Fujimura, A.
Vanin-1: a potential biomarker for nephrotoxicant-induced renal injury
Toxicology
290
82-88
2011
Homo sapiens, Rattus norvegicus
Jansen, P.A.; van Diepen, J.A.; Ritzen, B.; Zeeuwen, P.L.; Cacciatore, I.; Cornacchia, C.; van Vlijmen-Willems, I.M.; de Heuvel, E.; Botman, P.N.; Blaauw, R.H.; Hermkens, P.H.; Rutjes, F.P.; Schalkwijk, J.
Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease
ACS Chem. Biol.
8
530-534
2013
Rattus norvegicus (Q4KLZ0)
Boersma, Y.L.; Newman, J.; Adams, T.E.; Cowieson, N.; Krippner, G.; Bozaoglu, K.; Peat, T.S.
The structure of vanin 1: a key enzyme linking metabolic disease and inflammation
Acta Crystallogr. Sect. D
70
3320-3329
2014
Homo sapiens (O95497), Homo sapiens
Sayasith, K.; Sirois, J.; Lussier, J.G.
Expression, regulation, and promoter activation of vanin-2 (VNN2) in bovine follicles prior to ovulation
Biol. Reprod.
89
98
2013
Bos taurus (A5D9D1), Bos taurus, Bos taurus Holstein (A5D9D1)
Hosohata, K.; Ando, H.; Fujimura, A.
Early detection of renal injury using urinary vanin-1 in rats with experimental colitis
J. Appl. Toxicol.
34
184-190
2014
Rattus norvegicus (Q4KLZ0), Rattus norvegicus, Rattus norvegicus Wistar (Q4KLZ0)
Hosohata, K.; Ando, H.; Fujimura, A.
Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury
J. Pharmacol. Exp. Ther.
341
656-662
2012
Rattus norvegicus (Q4KLZ0), Rattus norvegicus Wistar (Q4KLZ0)
Wang, Y.J.; Tayo, B.O.; Bandyopadhyay, A.; Wang, H.; Feng, T.; Franceschini, N.; Tang, H.; Gao, J.; Sung, Y.J.; Sung, Y.J.; Elston, R.C.; Williams, S.M.; Cooper, R.S.; Mu, T.W.; Zhu, X.
The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function
PLoS Genet.
10
e1004641
2014
Homo sapiens (O95497)
Rommelaere, S.; Millet, V.; Rihet, P.; Atwell, S.; Helfer, E.; Chasson, L.; Beaumont, C.; Chimini, G.; Sambo, M.d.o. .R.; Viallat, A.; Penha-Goncalves, C.; Galland, F.; Naquet, P.
Serum pantetheinase/vanin levels regulate erythrocyte homeostasis and severity of malaria
Am. J. Pathol.
185
3039-3052
2015
Homo sapiens (O95497), Homo sapiens, Mus musculus (Q9Z0K8), Mus musculus, Mus musculus C57BL/6 (Q9Z0K8)
Lin, Y.; Gao, Y.; Ma, Z.; Li, Z.; Tang, C.; Qin, X.; Zhang, Z.; Wang, G.; Du, L.; Li, M.
Bioluminescent probe for detection of starvation-induced pantetheinase upregulation
Anal. Chem.
90
9545-9550
2018
Mus musculus (Q9Z0K8)
Yamashita, N.; Yashiro, M.; Ogawa, H.; Namba, H.; Nosaka, N.; Fujii, Y.; Morishima, T.; Tsukahara, H.; Yamada, M.
Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells
Biochem. Biophys. Res. Commun.
489
466-471
2017
Homo sapiens (O95497), Homo sapiens
Ferreira, D.W.; Naquet, P.; Manautou, J.E.
Influence of vanin-1 and catalytic products in liver during normal and oxidative stress conditions
Curr. Med. Chem.
22
2407-2416
2015
Mus musculus (Q9Z0K8), Mus musculus C57BL/6 (Q9Z0K8)
Bartucci, R.; Salvati, A.; Olinga, P.; Boersma, Y.L.
Vanin 1 its physiological function and role in diseases
Int. J. Mol. Sci.
20
3891
2019
Homo sapiens (O95497)
Bartucci, R.; Salvati, A.; Olinga, P.; Boersma, Y.L.
Vanin 1 its physiological function and role in diseases
Int. J. Mol. Sci.
20
E3891
2019
Rattus norvegicus, Sus scrofa (Q9BDJ5), Mus musculus (Q9Z0K8)
Kavian, N.; Mehlal, S.; Marut, W.; Servettaz, A.; Giessner, C.; Bourges, C.; Nicco, C.; Chereau, C.; Lemarechal, H.; Dutilh, M.F.; Cerles, O.; Guilpain, P.; Vuiblet, V.; Chouzenoux, S.; Galland, F.; Quere, I.; Weill, B.; Naquet, P.; Batteux, F.
Imbalance of the vanin-1 pathway in systemic sclerosis
J. Immunol.
197
3326-3335
2016
Mus musculus (Q9Z0K8), Mus musculus BALB/c (Q9Z0K8)
Giessner, C.; Millet, V.; Mostert, K.J.; Gensollen, T.; Vu Manh, T.P.; Garibal, M.; Dieme, B.; Attaf-Bouabdallah, N.; Chasson, L.; Brouilly, N.; Laprie, C.; Lesluyes, T.; Blay, J.Y.; Shintu, L.; Martin, J.C.; Strauss, E.; Galland, F.; Naquet, P.
Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity
Life Sci. Alliance
1
e201800073
2018
Mus musculus (Q9Z0K8)
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