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BRENDA support

Information on EC 3.5.1.131 - 1-carboxybiuret hydrolase

for references in articles please use BRENDA:EC3.5.1.131

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IUBMB Comments

The enzyme, characterized from the bacterium Pseudomonas sp. ADP, participates in the degradation of cyanuric acid, an intermediate in the degradation of s-triazine herbicides such as atrazine [2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine]. The enzyme is a heterotetramer composed of a catalytic subunit (AtzE) and an accessory subunit (AtzG) that stabilizes the complex.

The enzyme appears in viruses and cellular organisms

Synonyms
atzeg, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1-carboxybiuret + H2O = urea-1,3-dicarboxylate + NH3
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
cyanuric acid degradation I
Highest Expressing Human Cell Lines
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