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IUBMB Comments The enzyme, characterized from the bacterium Campylobacter jejuni , is involved in formation of a unique O -methyl phosphoramidate modification on specific sugar residues within the bacterium’s capsular polysaccharides.
Synonyms
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gamma-glutamyl-CDP-amidate hydrolase
N5-(cytidine 5'-diphosphoramidyl)-L-glutamine deacylase
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Cj1417c
Campylobacter jejuni subsp. jejuni serotype O:2
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gamma-glutamyl-CDP-amidate hydrolase
Campylobacter jejuni subsp. jejuni serotype O:2
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gamma-glutamyl-CDP-amidate hydrolase
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N5-(cytidine 5'-diphosphoramidyl)-L-glutamine + H2O = cytidine 5'-diphosphoramidate + L-glutamate
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N5-(cytidine 5'-diphosphoramidyl)-L-glutamine amidohydrolase
The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.
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N5-(cytidine 5'-diphosphoramidyl)-L-glutamine + H2O
cytidine 5'-diphosphoramidate + L-glutamate
additional information
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N5-(cytidine 5'-diphosphoramidyl)-L-glutamine + H2O
cytidine 5'-diphosphoramidate + L-glutamate
Campylobacter jejuni subsp. jejuni serotype O:2
Substrates: -
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N5-(cytidine 5'-diphosphoramidyl)-L-glutamine + H2O
cytidine 5'-diphosphoramidate + L-glutamate
Substrates: -
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additional information
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Campylobacter jejuni subsp. jejuni serotype O:2
Substrates: L-glutamine phosphate is a very poor substrate
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additional information
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Substrates: L-glutamine phosphate is a very poor substrate
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0.028
N5-(cytidine 5'-diphosphoramidyl)-L-glutamine
Campylobacter jejuni subsp. jejuni serotype O:2
pH 8.0, 25°C
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0.55
N5-(cytidine 5'-diphosphoramidyl)-L-glutamine
Campylobacter jejuni subsp. jejuni serotype O:2
pH 8.0, 25°C
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20
N5-(cytidine 5'-diphosphoramidyl)-L-glutamine
Campylobacter jejuni subsp. jejuni serotype O:2
pH 8.0, 25°C
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8
Campylobacter jejuni subsp. jejuni serotype O:2
assay at
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Campylobacter jejuni subsp. jejuni serotype O:2
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UniProt
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UniProt
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Highest Expressing Human Cell Lines
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Cell Line Links
Gene Links
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GCDPH_CAMJE
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
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23500
Swiss-Prot
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Taylor, Z.; Brown, H.; Holden, H.; Raushel, F.
Biosynthesis of nucleoside diphosphoramidates in Campylobacter jejuni
Biochemistry
56
6079-6082
2017
Campylobacter jejuni subsp. jejuni serotype O:2 (Q0P8J7), Campylobacter jejuni subsp. jejuni serotype O:2 ATCC 700819 (Q0P8J7)
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