Disease on EC 3.5.1.11 - penicillin amidase
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Aspartylglucosaminuria
Regional distribution of glycoasparagine storage material in the brain in aspartylglycosaminuria.
Bacterial Infections
Crystal structure of penicillin G acylase from the Bro1 mutant strain of Providencia rettgeri.
Brain Diseases
Syntheses, in vitro urease inhibitory activities of urea and thiourea derivatives of tryptamine, their molecular docking and cytotoxic studies.
Burkitt Lymphoma
The effect of Yarrowia lipolytical-asparaginase on apoptosis induction and inhibition of growth in Burkitt's lymphoma Raji and acute lymphoblastic leukemia MOLT-4 cells.
Canavan Disease
Brain N-acetylaspartate as a molecular water pump and its role in the etiology of Canavan disease: a mechanistic explanation.
Canavan Disease
Purification, characterization, and localization of aspartoacylase from bovine brain.
Carcinoma
Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis.
Dehydration
Improved X-ray diffraction from Bacillus megaterium penicillin G acylase crystals through long cryosoaking dehydration.
Glioma
Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH.
Glioma
Synthesis and characterization of diazomethylarachidonyl ketone: an irreversible inhibitor of N-arachidonylethanolamine amidohydrolase.
Hepatic Encephalopathy
Syntheses, in vitro urease inhibitory activities of urea and thiourea derivatives of tryptamine, their molecular docking and cytotoxic studies.
Infections
Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors.
Kidney Calculi
Syntheses, in vitro urease inhibitory activities of urea and thiourea derivatives of tryptamine, their molecular docking and cytotoxic studies.
Lymphoma, Non-Hodgkin
The effect of Yarrowia lipolytical-asparaginase on apoptosis induction and inhibition of growth in Burkitt's lymphoma Raji and acute lymphoblastic leukemia MOLT-4 cells.
Neoplasms
Assay and purification of omega-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the alpha-keto acid analogues of glutamine and asparagine.
Neoplasms
Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.
Neoplasms
Purification, characterization, and anticancer and antioxidant activities of L-glutaminase from Aspergillus versicolor Faesay4.
Neuroblastoma
Purification and characterization of a nicotinamide deamidase released into the growth medium of neuroblastoma in vitro.
Paratuberculosis
Directed Evolution of a Quorum-Quenching Lactonase from Mycobacterium avium subsp. paratuberculosis K-10 in the Amidohydrolase Superfamily.
Peptic Ulcer
Syntheses, in vitro urease inhibitory activities of urea and thiourea derivatives of tryptamine, their molecular docking and cytotoxic studies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Construction of expression systems for Escherichia coli asparaginase II and two-step purification of the recombinant enzyme from periplasmic extracts.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interaction of alpha 2-macroglobulin with L-asparaginase.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Marine microbial L-asparaginase: Biochemistry, molecular approaches and applications in tumor therapy and in food industry.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Optimization of culture conditions and bench-scale production of anticancer enzyme L-asparaginase by submerged fermentation from Aspergillus terreus CCT 7693.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Poly (lactic-co-glycolic acid) nanospheres allow for high l-asparaginase encapsulation yield and activity.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The effect of Yarrowia lipolytical-asparaginase on apoptosis induction and inhibition of growth in Burkitt's lymphoma Raji and acute lymphoblastic leukemia MOLT-4 cells.
Tuberculosis
Purification, characterization, and genetic analysis of Mycobacterium tuberculosis urease, a potentially critical determinant of host-pathogen interaction.
Tuberculosis
Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA).
Whooping Cough
Endogenous cannabinoid anandamide directly inhibits voltage-dependent Ca(2+) fluxes in rabbit T-tubule membranes.
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