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Information on EC 3.4.24.B19 - i-AAA protease and Organism(s) Arabidopsis thaliana and UniProt Accession O80983

for references in articles please use BRENDA:EC3.4.24.B19
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B19 i-AAA protease
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: O80983
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
proteolytic degradation of proteins
Synonyms
iap-1, yme1p, ftsh4, i-aaa protease, osd1 protein, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CAS REGISTRY NUMBER
COMMENTARY hide
405910-55-6
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Tim17-2 + H2O
?
show the reaction diagram
substrate is an essential component of the mitochondrial TIM17:23 translocase
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
abundance of the Tim17-2 protein, an essential component of the TIM17:23 translocase, is directly controlled by the proteolytic activity of FTSH4. Plants that are lacking functional FTSH4 protease display a significantly enhanced capacity of preprotein import through the TIM17:23-dependent pathway
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
FTSH4_ARATH
717
0
77275
Swiss-Prot
-
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Opalinska, M.; Parys, K.; Murcha, M.W.; Janska, H.
The plant i-AAA protease controls the turnover of an essential mitochondrial protein import component
J. Cell Sci.
131
jcs200733
2018
Arabidopsis thaliana (O80983), Arabidopsis thaliana Col-0 (O80983)
Manually annotated by BRENDA team