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Information on EC 3.4.24.69 - bontoxilysin

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.69 bontoxilysin
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UNIPROT: C5IWN7 not found.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevin (also known as neuronal vesicle-associated membrane protein, VAMP), synaptosome-associated protein of 25 kDa (SNAP25) or syntaxin. No detected action on small molecule substrates
Synonyms
botulinum toxin, botulinum toxin type a, bont-a, bont/a, onabotulinumtoxina, botulinum neurotoxin, bonta, incobotulinumtoxina, bont/b, abobotulinumtoxina, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
botulinum neurotoxin type F
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BoNT
-
-
-
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BoNT/B
-
-
-
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BoNT/C1
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-
-
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BoNT/D
-
-
-
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BoNT/E
-
-
-
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BoNT/F
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-
-
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BoNT/G
-
-
-
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Bontoxilysin C1
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Botulinum neurotoxin
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-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
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-
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CAS REGISTRY NUMBER
COMMENTARY hide
107231-12-9
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
gene bont/F; proteolytic and nonproteolytic strains, bivalent strains, including Bf and Af, gene bont/A
UniProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
C5IWN7_CLOBO
1278
0
146600
TrEMBL
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
genes bont, 6 subtypes, DNA and amino acid sequence determination and analysis. The genes from proteolytic, group I, strains form subtypes F1 through F5, while the genes from nonproteolytic, group II, strains form subtype F6, phylogenetic analysis
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Raphael, B.H.; Choudoir, M.J.; Luquez, C.; Fernandez, R.; Maslanka, S.E.
Sequence diversity of genes encoding botulinum neurotoxin type F
Appl. Environ. Microbiol.
76
4805-4812
2010
Clostridium botulinum (C5IWN7), Clostridium botulinum (D2KCK3), Clostridium botulinum (P30996), Clostridium botulinum (Q58GH1), Clostridium botulinum, Clostridium baratii (Q45851), Clostridium baratii
Manually annotated by BRENDA team