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Disease on EC 3.4.24.39 - deuterolysin

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Bardet-Biedl Syndrome
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
Breast Neoplasms
A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Carcinogenesis
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Carcinoma
A Luminacin D Analog HL142 Inhibits Ovarian Tumor Growth and Metastasis by Reversing EMT and Attenuating the TGF? and FAK Pathways.
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
Carcinoma, Ovarian Epithelial
Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer.
Colorectal Neoplasms
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Encephalomyelitis, Autoimmune, Experimental
Treatment of an encephalitogenic peptide from guinea pig myelin basic protein with alpha-protease and thermolysin. Isolation of fragments and determination of cleavage sites.
Furunculosis
Innate and adaptive immune responses of Arctic charr (Salvelinus alpinus, L.) during infection with Aeromonas salmonicida subsp. achromogenes and the effect of the AsaP1 toxin.
Glaucoma, Open-Angle
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
Infections
Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Innate and adaptive immune responses of Arctic charr (Salvelinus alpinus, L.) during infection with Aeromonas salmonicida subsp. achromogenes and the effect of the AsaP1 toxin.
No Significant Effect of ASAP1 Gene Variants on the Susceptibility to Tuberculosis in Chinese Population.
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
Toxoid construction of AsaP1, a lethal toxic aspzincin metalloendopeptidase of Aeromonas salmonicida subsp. achromogenes, and studies of its activity and processing.
[ASAP1 knockdown reduces migration of RAW264.7 cells infected with Mycobacterium tuberculosis].
Liver Cirrhosis
Silybin-vitamin E-phospholipids complex reduces liver fibrosis in patients with chronic hepatitis C treated with pegylated interferon ? and ribavirin.
Lymphatic Metastasis
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Neoplasm Metastasis
A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
ASAP1, a gene at 8q24, is associated with prostate cancer metastasis.
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis.
Neoplasms
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.
Functional Expression and Characterization of Human Myristoylated-Arf1 in Nanodisc Membrane Mimetics.
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
Loss of EGFR-ASAP1 signaling in metastatic and unresectable hepatoblastoma.
MiR-203 is downregulated in laryngeal squamous cell carcinoma and can suppress proliferation and induce apoptosis of tumours.
Synthesis and HPLC analysis of enzymatically cleavable linker consisting of poly(ethylene glycol) and dipeptide for the development of immunoconjugate.
The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis.
Ovarian Neoplasms
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
Prostatic Neoplasms
ASAP1, a gene at 8q24, is associated with prostate cancer metastasis.
Retinitis Pigmentosa
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
Squamous Cell Carcinoma of Head and Neck
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Stomach Neoplasms
ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation.
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Thyroid Cancer, Papillary
Knockout of ASAP1 induces autophagy in papillary thyroid carcinoma by inhibiting the mTOR signaling pathway.
Triple Negative Breast Neoplasms
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Tuberculosis
A Common Variant of ASAP1 Is Associated with Tuberculosis Susceptibility in the Han Chinese Population.
Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.
ASAP1 gene polymorphisms are associated with susceptibility to tuberculosis in a Chinese Xinjiang Muslim population.
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Genetic variants at 18q11.2 and 8q24 identified by genome-wide association studies were not associated with pulmonary tuberculosis risk in Chinese population.
No Significant Effect of ASAP1 Gene Variants on the Susceptibility to Tuberculosis in Chinese Population.
Regulator of dendritic cell migration, ASAP1 is associated with increased susceptibility to tuberculosis.
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
[ASAP1 knockdown reduces migration of RAW264.7 cells infected with Mycobacterium tuberculosis].
Urinary Bladder Neoplasms
Detection of molecular signatures and pathways shared in inflammatory bowel disease and colorectal cancer: A bioinformatics and systems biology approach.