Disease on EC 3.4.24.39 - deuterolysin
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Bardet-Biedl Syndrome
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
Breast Neoplasms
A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.
Breast Neoplasms
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Carcinogenesis
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.
Carcinogenesis
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Carcinoma
A Luminacin D Analog HL142 Inhibits Ovarian Tumor Growth and Metastasis by Reversing EMT and Attenuating the TGF? and FAK Pathways.
Carcinoma
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Carcinoma
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.
Carcinoma
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
Carcinoma, Ovarian Epithelial
Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer.
Colorectal Neoplasms
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Encephalomyelitis, Autoimmune, Experimental
Treatment of an encephalitogenic peptide from guinea pig myelin basic protein with alpha-protease and thermolysin. Isolation of fragments and determination of cleavage sites.
Furunculosis
Innate and adaptive immune responses of Arctic charr (Salvelinus alpinus, L.) during infection with Aeromonas salmonicida subsp. achromogenes and the effect of the AsaP1 toxin.
Glaucoma, Open-Angle
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
Infections
Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.
Infections
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Infections
Innate and adaptive immune responses of Arctic charr (Salvelinus alpinus, L.) during infection with Aeromonas salmonicida subsp. achromogenes and the effect of the AsaP1 toxin.
Infections
No Significant Effect of ASAP1 Gene Variants on the Susceptibility to Tuberculosis in Chinese Population.
Infections
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
Infections
Toxoid construction of AsaP1, a lethal toxic aspzincin metalloendopeptidase of Aeromonas salmonicida subsp. achromogenes, and studies of its activity and processing.
Infections
[ASAP1 knockdown reduces migration of RAW264.7 cells infected with Mycobacterium tuberculosis].
Liver Cirrhosis
Silybin-vitamin E-phospholipids complex reduces liver fibrosis in patients with chronic hepatitis C treated with pegylated interferon ? and ribavirin.
Lymphatic Metastasis
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Lymphatic Metastasis
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Neoplasm Metastasis
A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.
Neoplasm Metastasis
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Neoplasm Metastasis
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Neoplasm Metastasis
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Neoplasm Metastasis
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Neoplasm Metastasis
Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.
Neoplasm Metastasis
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
Neoplasm Metastasis
The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis.
Neoplasms
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
Neoplasms
An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide.
Neoplasms
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Neoplasms
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Neoplasms
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.
Neoplasms
Functional Expression and Characterization of Human Myristoylated-Arf1 in Nanodisc Membrane Mimetics.
Neoplasms
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Neoplasms
Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.
Neoplasms
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
Neoplasms
MiR-203 is downregulated in laryngeal squamous cell carcinoma and can suppress proliferation and induce apoptosis of tumours.
Neoplasms
Synthesis and HPLC analysis of enzymatically cleavable linker consisting of poly(ethylene glycol) and dipeptide for the development of immunoconjugate.
Neoplasms
The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis.
Ovarian Neoplasms
Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.
Retinitis Pigmentosa
A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.
Squamous Cell Carcinoma of Head and Neck
ASAP1 mediates the invasive phenotype of human laryngeal squamous cell carcinoma to affect survival prognosis.
Stomach Neoplasms
ADP ribosylation factor guanylate kinase 1 promotes the malignant phenotype of gastric cancer by regulating focal adhesion kinase activation.
Stomach Neoplasms
Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
Thyroid Cancer, Papillary
Knockout of ASAP1 induces autophagy in papillary thyroid carcinoma by inhibiting the mTOR signaling pathway.
Triple Negative Breast Neoplasms
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Tuberculosis
A Common Variant of ASAP1 Is Associated with Tuberculosis Susceptibility in the Han Chinese Population.
Tuberculosis
Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration.
Tuberculosis
ASAP1 gene polymorphisms are associated with susceptibility to tuberculosis in a Chinese Xinjiang Muslim population.
Tuberculosis
ASAP1 regulates the uptake of Mycobacterium tuberculosis H37Ra in THP1-derived macrophages by remodeling actin cytoskeleton.
Tuberculosis
Genetic variants at 18q11.2 and 8q24 identified by genome-wide association studies were not associated with pulmonary tuberculosis risk in Chinese population.
Tuberculosis
No Significant Effect of ASAP1 Gene Variants on the Susceptibility to Tuberculosis in Chinese Population.
Tuberculosis
Regulator of dendritic cell migration, ASAP1 is associated with increased susceptibility to tuberculosis.
Tuberculosis
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
Tuberculosis
[ASAP1 knockdown reduces migration of RAW264.7 cells infected with Mycobacterium tuberculosis].
Urinary Bladder Neoplasms
Detection of molecular signatures and pathways shared in inflammatory bowel disease and colorectal cancer: A bioinformatics and systems biology approach.
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