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Disease on EC 3.4.24.24 - gelatinase A

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DISEASE
TITLE OF PUBLICATION
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Aberrant Crypt Foci
Anti-inflammatory and anticancer effects of p-methoxycinnamic acid, an active phenylpropanoid, against 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
Abortion, Habitual
Altered expression of genes involved in the production and degradation of endometrial extracellular matrix in patients with unexplained infertility and recurrent miscarriages.
Abortion, Spontaneous
The association of polymorphisms in promoter region of MMP2 and MMP9 with recurrent spontaneous abortion risk in Chinese population.
Abscess
Anti-MMP-9 Antibody: A Promising Therapeutic Strategy for Treatment of Inflammatory Bowel Disease Complications with Fibrosis.
Enzymatically active Peptostreptococcus magnus: association with site of infection.
The zymographic evaluation of gelatinase (MMP-2 and -9) levels in acute and chronic periapical abscesses.
Acne Vulgaris
A comparative study of MMP-1, MMP-2, and TNF-? expression in different acne vulgaris lesions.
Effects of 420-nm intense pulsed light in an acne animal model.
Hypertrophic post-acne scarring is associated with a single nucleotide polymorphism (rs243865) in the matrix metalloproteinase-2 gene.
Polymorphisms in the promoters of MMP-2 and TIMP-2 genes in patients with acne vulgaris.
Role of MMP-2(-1306 C/T) and TIMP-2(-418G/C) Polymorphism in Chinese Han Patients with Acne Vulgaris.
Acquired Immunodeficiency Syndrome
Determination of MMP-2 and -9 activities in synovial fluid of horses with osteoarthritic and arthritic joint diseases using gelatin zymography and immunocapture activity assays.
Expression levels of matrix metalloproteinase (MMP)-9 and its specific inhibitor TIMP-1, in septic and aseptic arthritis of the knee.
Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases.
Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity.
MMP2 expression is a prognostic marker for primary melanoma patients.
Modulation of MMP-2 and MMP-9 through connected pathways and growth factors is critical for extracellular matrix balance of intra-articular ligaments.
Molecular dynamics simulation study on the interaction of collagen like peptides with gelatinase-a (mmp-2).
The EGF signaling pathway influences cell migration and the secretion of metalloproteinases by myoepithelial cells in pleomorphic adenoma.
Acromegaly
Matrix metalloproteinase 2 (MMP-2) levels are increased in active acromegaly patients.
Reductions of circulating matrix metalloproteinase 2 and vascular endothelial growth factor levels after treatment with pegvisomant in subjects with acromegaly.
Acute Coronary Syndrome
Cardiometabolic risk factors and acute kidney injury based on urinary neutrophil gelatinase associated lipocalin (NGALu) in acute coronary syndrome patients.
Comparison between metalloproteinases-2 and -9 in healthy subjects, diabetics, and subjects with acute coronary syndrome.
Estimating the prevalence of elevated plasma neutrophil gelatinase associated lipocalin level in patients with acute coronary syndromes and its association with outcomes.
Expressions and clinical significance of factors related to acute coronary syndrome.
Matrix Metalloproteinase-2 predicts mortality in patients with acute coronary syndrome.
Matrix metalloproteinases in coronary artery disease.
Metalloproteinase-2 and -9 in diabetic and nondiabetic subjects during acute coronary syndromes.
Metalloproteinases-2, -9 and TIMP-1 expression in stable and unstable coronary plaques undergoing PCI.
MiR-29b mimics promotes cell apoptosis of smooth muscle cells via targeting on MMP-2.
Platelets release matrix metalloproteinase-2 in the coronary circulation of patients with acute coronary syndromes: possible role in sustained platelet activation.
Serum levels of neutrophil Gelatinase associated Lipocalin (NGAL) predicts hemodialysis after coronary angiography in high risk patients with acute coronary syndrome.
Transcription activity of MMP-2 and MMP-9 metalloproteinase genes and their tissue inhibitor (TIMP-2) in acute coronary syndrome patients.
[Changes in serum level of carboxy-terminal telopeptide of type I collagen in patients with coronary heart disease].
Acute Kidney Injury
Acute kidney injury during an ultra-distance race.
An E-selectin targeting and MMP-2-responsive dextran-curcumin polymeric prodrug for targeted therapy of acute kidney injury.
An intracellular matrix metalloproteinase-2 isoform induces tubular regulated necrosis: implications for acute kidney injury.
Bedside biomarkers in pediatric cardio renal injuries in emergency.
Can We Use Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Levels to Predict Acute Kidney Injury in Neonate and Infants Undergoing Cardiac Surgery? Not Yet….
Cardiometabolic risk factors and acute kidney injury based on urinary neutrophil gelatinase associated lipocalin (NGALu) in acute coronary syndrome patients.
Cell Cycle Biomarkers and Soluble Urokinase-Type Plasminogen Activator Receptor for the Prediction of Sepsis-Induced Acute Kidney Injury Requiring Renal Replacement Therapy: A Prospective, Exploratory Study.
Comparison of urinary TIMP-2 and IGFBP7 cut-offs to predict acute kidney injury in critically ill patients: A PRISMA-compliant systematic review and meta-analysis.
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Diagnostic value of urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 for acute kidney injury: a meta-analysis.
Diagnostic Value of Urine Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Acute Kidney Injury: A Meta-Analysis.
Early Diagnosis Of Acute Kidney Injury By Urinary Neutrophil Gelatinase Associated Lipocalin In Adult Critically Ill Patients.
Effect of pentoxifylline on preventing acute kidney injury after cardiac surgery by measuring urinary neutrophil gelatinase - associated lipocalin.
Epidemiology of acute kidney injury and the role of urinary [TIMP-2]·[IGFBP7]: a prospective cohort study in critically ill obstetric patients.
Estimation of urine neutrophil gelatinase associated lipocalin in septic patients with and without acute kidney injury.
Evaluation of NGAL Test™, a fully-automated neutrophil gelatinase-associated lipocalin (NGAL) immunoassay on Beckman Coulter AU 5822.
Evaluation of urinary tissue inhibitor of metalloproteinase-2 in acute kidney injury: a prospective observational study.
Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial.
Hepatic ischemia-reperfusion injury associates with acute kidney injury in liver transplantation: Prospective cohort study.
IL-6-mediated hepatocyte production is the primary source of plasma and urine neutrophil gelatinase-associated lipocalin during acute kidney injury.
Importance of determination of urine neutrophile gelatinase associated lipocalin in early detection of acute kidney injury.
Inhibition of matrix metalloproteinases reduces ischemia-reperfusion acute kidney injury.
Ischemia-reperfusion injury stimulates gelatinase expression and activity in kidney glomeruli.
Kinetics of the cell cycle arrest biomarkers (TIMP-2*IGFBP-7) for prediction of acute kidney injury in infants after cardiac surgery.
Kinetics of Urinary Cell Cycle Arrest Markers for Acute Kidney Injury Following Exposure to Potential Renal Insults.
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
Neutrophil Gelatinase Associated Lipocalin (NGAL) in Leptospirosis Acute Kidney Injury: A Multicenter Study in Thailand.
Neutrophil Gelatinase Associated Lipocalin as a Biomarker for Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Grafting with Cardiopulmonary Bypass.
Neutrophil gelatinase associated lipocalin as an indicator of acute kidney injury and inflammation in burned children.
Neutrophil gelatinase associated lipocalin in acute kidney injury.
Neutrophil Gelatinase Associated Lipocalin is an Independent Predictor of Poor Prognosis in Cases of Papillary Renal Cell Carcinoma.
Novel renal markers for the assessment of renal integrity in patients undergoing knee arthroplasty - a pilot study.
Plasma Neutrophil Gelatinase Associated Lipocalin (NGAL) - Early Biomarker for Acute Kidney Injury in Critically Ill Patients.
Plasma Neutrophil Gelatinase Associated Lipocalin Diagnosed Acute Kidney Injury in Patients With Systemic Inflammatory Disease And Sepsis.
Predicting Severity of Acute Kidney Injury in Term Neonates with Perinatal Asphyxia Using Urinary Neutrophil Gelatinase Associated Lipocalin.
Renal biomarkers for the prediction of cardiovascular disease.
Renal neutrophil gelatinase associated lipocalin expression in lipopolysaccharide-induced acute kidney injury in the rat.
Reno-protective effect of berberine.
Reversibility of Acute Kidney Injury in Medical ICU Patients: Predictability Performance of Urinary Tissue Inhibitor of Metalloproteinase-2 x Insulin-Like Growth Factor-Binding Protein 7 and Renal Resistive Index.
Role of matrix metalloproteinase-2 in recovery after tubular damage in acute kidney injury in mice.
Serial Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 and the Prognosis for Acute Kidney Injury over the Course of Critical Illness.
Serum and Plasma Neutrophil Gelatinase Associated Lipocalin (NGAL) Levels are Not Equivalent in Patients Admitted to Intensive Care.
Serum neutrophil gelatinase associated lipocalin (NGAL) and cystatin C as early predictors of contrast-induced acute kidney injury in patients undergoing percutaneous coronary intervention.
Serum Neutrophil Gelatinase Associated Lipocalin (NGAL) Outperforms Serum Creatinine in Detecting Sepsis-Induced Acute Kidney Injury, Experiments on Bilateral Nephrectomy and Bilateral Ureter Obstruction Mouse Models.
The effect of early renal replacement therapy guided by plasma neutrophil gelatinase associated lipocalin on outcome of acute kidney injury: A feasibility study.
The effectiveness of urinary TIMP-2 and IGFBP-7 in predicting acute kidney injury in critically ill neonates.
The use of plasma and urine neutrophil gelatinase associated lipocalin (NGAL) and Cystatin C in early diagnosis of septic acute kidney injury in critically ill patients.
Tissue inhibitor metalloproteinase-2 (TIMP-2) • IGF-binding protein-7 (IGFBP7) levels are associated with adverse outcomes in patients in the intensive care unit with acute kidney injury.
Ultra-high-performance liquid chromatography-mass spectrometry method for neutrophil gelatinase-associated lipocalin as a predictive biomarker in acute kidney injury.
Urinary Kidney Injury Molecule-1 but Not Urinary Neutrophil Gelatinase Associated Lipocalin Is Increased after Short Maximal Exercise.
Urinary Neutrophil Gelatinase Associated Lipocalin (NGAL) for Early Diagnosis of Acute Kidney Injury in Renal Transplant Recipients.
Urinary neutrophil gelatinase associated lipocalin as a biomarker in ifosfamide induced chronic renal failure.
Urinary Neutrophil Gelatinase Associated Lipocalins (NGALs) predict acute kidney injury post liver transplant.
Urinary Tissue Inhibitor of Metalloproteinase and Insulin-like Growth Factor-7 as Early Biomarkers of Delayed Graft Function After Kidney Transplantation.
Urinary Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) • Insulin-Like Growth Factor-Binding Protein 7 (IGFBP7) Predicts Adverse Outcome in Pediatric Acute Kidney Injury.
Urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 as biomarkers of patients with established acute kidney injury.
Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis.
Urine neutrophil gelatinase associated lipocalin as an early marker of acute kidney injury in hematopoietic stem cell transplantation patients.
Urine neutrophil gelatinase-associated lipocalin levels predict acute kidney injury in acute decompensated heart failure patients.
Urine/Plasma Neutrophil Gelatinase Associated Lipocalin Ratio Is a Sensitive and Specific Marker of Subclinical Acute Kidney Injury in Mice.
Value of point-of-care neutrophil gelatinase associated lipocalin in early diagnosis of acute kidney injury in patients with left ventricular systolic dysfunction after coronary angiography.
[NGAL, biomarker of acute kidney injury in 2012.]
[Urinary neutrophil gelatinase-associated lipocalin (uNGAL) and early diagnosis of paraquat poisoning patients with acute kidney injury].
Acute Lung Injury
3, 4-dihydroxybenzalacetone attenuates lipopolysaccharide-induced inflammation in acute lung injury via down-regulation of MMP-2 and MMP-9 activities through suppressing ROS-mediated MAPK and PI3K/AKT signaling pathways.
A rise of MMP-2 and MMP-9 in bronchoalveolar lavage fluid is associated with acute lung injury after cardiopulmonary bypass in a swine model.
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Dexamethasone Ameliorates H2S-Induced Acute Lung Injury by Alleviating Matrix Metalloproteinase-2 and -9 Expression.
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Involvement of lung interstitial proteoglycans in development of hydraulic- and elastase-induced edema.
Ionizing radiation enhances matrix metalloproteinase-2 production in human lung epithelial cells.
Matrix metalloproteinases and matrix metalloproteinase inhibitors in acute lung injury.
Metalloproteinase inhibition reduces lung injury and improves survival after cecal ligation and puncture in rats.
Novel 5-Hydroxy, 5-Substituted Benzenesulfonamide Pyrimidine-2,4,6-Triones Attenuate Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of the Gelatinases, MMP-2 and MMP-9.
Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury.
The endothelin axis and gelatinase activity in alveolar macrophages after brain-stem death injury: a pilot study.
[Effects of adenovirus-delivered angiopoietin-1 siRNA on expression of matrix metalloproteinases in rats with acute lung injury induced by phosgene].
[Effects of unfractionated heparin on expression of metalloproteinase-2 and -9 in acute lung injury rats].
[Expression of various matrix metalloproteinases in mice with hyperoxia induced acute lung injury.]
Adenocarcinoma
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
alpha-Mangostin, a novel dietary xanthone, suppresses TPA-mediated MMP-2 and MMP-9 expressions through the ERK signaling pathway in MCF-7 human breast adenocarcinoma cells.
Analyses of matrix metalloproteinases and their inhibitors in cyst fluid of serous ovarian tumors.
Analysis of the capillary architecture in the precursors of prostate cancer: recent findings and new concepts.
Androgen-repressed phenotype in human prostate cancer.
Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
Circulating levels of VCAM and MMP-2 may help identify patients with more aggressive prostate cancer.
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Comparative Role of Matrixins in Diagnostics of Parotid Gland Tumors.
Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
Detection of serum MMPs in tumor-bearing hamsters.
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Distinct endobronchial expression of matrix-metalloproteinases (MMP) and their endogenous inhibitors in lung cancer.
Effects of EGF and TGF-alpha on invasion and proteinase expression of uterine cervical adenocarcinoma OMC-4 cells.
Effects of sex steroids and growth factors on migration and invasion of endometrial adenocarcinoma SNG-M cells in vitro.
Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer.
Evaluation of MMP-9 and MMP-2 and their suppressor TIMP-1 and TIMP-2 in adenocarcinoma of esophagogastric junction.
Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma.
Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors.
Expression of Fhit, cell adhesion molecules and matrix metalloproteinases in atypical adenomatous hyperplasia and pulmonary adenocarcinoma.
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung.
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix.
Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Expression of Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis.
Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination.
Expressions of Matrix Metalloproteinases 2, 7, and 9 in Carcinogenesis of Pancreatic Ductal Adenocarcinoma.
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas.
High serum TIMP-1 is associated with adverse prognosis in endometrial carcinoma.
Hypoxia augments gelatinase activity in a variety of adenocarcinomas in vitro.
Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial-mesenchymal transition.
Immunocytochemical detection of the expression of members of the matrix metalloproteinase family in adenocarcinomas of the pancreas.
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Immunohistochemical analysis of type IV collagenase expression in prostatic hyperplasia and adenocarcinoma.
Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia.
Immunoreactivity of CD99 in stomach cancer.
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Increased expression of the 72-kd type IV collagenase in prostatic adenocarcinoma. Demonstration by immunohistochemistry and in situ hybridization.
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells.
Inhibitory effect of acetylsalicylic acid on metalloproteinase activity in human lung adenocarcinoma at different stages of differentiation.
Intrabronchial orthotopic propagation of human lung adenocarcinoma--characterizations of tumorigenicity, invasion and metastasis.
KAI1 is a potential target for anti-metastasis in pancreatic cancer cells.
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Location of 72-kd metalloproteinase (type IV collagenase) in untreated prostatic adenocarcinoma.
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.
Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) in preoperative serum as independent prognostic markers in patients with colorectal cancer.
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma.
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Matrix metalloproteinase-triggered denuding of engineered gold nanoparticles for selective cell uptake.
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in colonic adenomas-adenocarcinomas.
Metalloproteinases and tissue inhibitor of metalloproteinase 1 (TIMP-1) in endometrial flushings from pre- and post-menopausal women and from women with endometrial adenocarcinoma.
Metastasis-associated alterations in phospholipids and fatty acids of human prostatic adenocarcinoma cell lines.
MMP-13 In-Vivo Molecular Imaging Reveals Early Expression in Lung Adenocarcinoma.
MMP-2 activation and stepwise progression of pulmonary adenocarcinoma: analysis of MMP-2 and MMP-9 with gelatin zymography.
Modulation of monocyte matrix metalloproteinase-2 by breast adenocarcinoma cells.
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.
Nrf2-peroxiredoxin I axis in polymorphous adenocarcinoma is associated with low matrix metalloproteinase 2 level.
Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma.
Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.
Overexpression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in liver from patients with gastrointestinal adenocarcinoma and no detectable metastasis.
Papers to appear in forthcoming issues
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting ?5?1 integrin to downregulate Akt and MMP-2.
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma.
SKOV-3 cell imaging by paramagnetic particles labeled with hairpin cell-penetrating peptides.
Small adenocarcinoma of the lung: prognostic significance of central fibrosis chiefly because of its association with angiogenesis and lymphangiogenesis.
Soybean Bowman-Birk Protease Inhibitor (BBI): Identification of the Mechanisms of BBI Suppressive Effect on Growth of Two Adenocarcinoma Cell Lines: AGS and HT29.
Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection.
Tamoxifen exerts oestrogen-agonistic effects on proliferation and plasminogen activation, but not on gelatinase activity, glycogen metabolism and p53 protein expression, in cultures of oestrogen-responsive human endometrial adenocarcinoma cells.
The ?-adrenoceptor antagonist, propranolol, induces human gastric cancer cell apoptosis and cell cycle arrest via inhibiting nuclear factor ?B signaling.
The association of transforming growth factor-beta 1 with myometrial invasion of endometrial carcinomas through effects on matrix metalloproteinase.
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor 2 in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters.
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis.
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
The role of inflammation in patients with intraductal mucinous neoplasm of the pancreas and in those with pancreatic adenocarcinoma.
Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase.
[Expression and clinical significance of CD147 and MMP-2 ?in squamous cell carcinoma and adenocarcinoma of the lungs].
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
[MMP-2 expression (type IV collagenase) in gastric cancer]
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
[Prognostic value of stromal immunolabelling by MMP-2, MT1-MMP and TIMP-2 in clinically localized prostate cancer]
Adenocarcinoma of Lung
Alpha-mangostin suppresses phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 expressions via alphavbeta3 integrin/FAK/ERK and NF-kappaB signaling pathway in human lung adenocarcinoma A549 cells.
Basement membrane patterns, gelatinase A and tissue inhibitor of metalloproteinase-2 expressions, and stromal fibrosis during the development of peripheral lung adenocarcinoma.
Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9.
Computed tomographic images reflect the biologic behavior of small lung adenocarcinoma: they correlate with cell proliferation, microvascularization, cell adhesion, degradation of extracellular matrix, and K-ras mutation.
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases.
Gelatinase activity of matrix metalloproteinases during first-line chemotherapy in lung adenocarcinoma patients: an initial approach.
Granulocyte, granulocyte-macrophage, and macrophage colony-stimulating factors can stimulate the invasive capacity of human lung cancer cells.
Growth pattern correlates with the distribution of basement membrane and prognosis in lung adenocarcinoma.
HoxB7 PROMOTES GROWTH AND METASTASIS OF LUNG ADENOCARCINOMA CELLS THROUGH REGULATION OF THE TGF-?/SMAD3 SIGNALING.
Human papillomavirus up-regulates MMP-2 and MMP-9 expression and activity by inducing interleukin-8 in lung adenocarcinomas.
Inhibitory effect of acetylsalicylic acid on metalloproteinase activity in human lung adenocarcinoma at different stages of differentiation.
Intrabronchial orthotopic propagation of human lung adenocarcinoma--characterizations of tumorigenicity, invasion and metastasis.
Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung.
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
N-myc downstream regulated gene 2 overexpression reduces matrix metalloproteinase-2 and -9 activities and cell invasion of A549 lung cancer cell line in vitro.
Novel ternary vanadium-betaine-peroxido species suppresses H-ras and matrix metalloproteinase-2 expression by increasing reactive oxygen species-mediated apoptosis in cancer cells.
POU5F1 enhances the invasiveness of cancer stem-like cells in lung adenocarcinoma by upregulation of MMP-2 expression.
Resveratrol analog-3,5,4'-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression.
Silencing of LINC00461 enhances radiosensitivity of lung adenocarcinoma cells by down-regulating HOXA10 via microRNA-195.
Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells.
Suppression on metastasis by rhubarb through modulation on MMP-2 and uPA in human A549 lung adenocarcinoma: An ex vivo approach.
ZO-2 Suppresses Cell Migration Mediated by a Reduction in Matrix Metalloproteinase 2 in Claudin-18-Expressing Lung Adenocarcinoma A549 Cells.
[Anti-sense nucleic acid of CyclinD1 induces apoptosis of lung adenocarcinoma cancer cell A549.]
[Effects of Cullin1 on the Biological Characteristics of Lung Adenocarcinoma?A549 and H1395 Cells].
Adenocarcinoma, Bronchiolo-Alveolar
Basement membrane patterns, gelatinase A and tissue inhibitor of metalloproteinase-2 expressions, and stromal fibrosis during the development of peripheral lung adenocarcinoma.
Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung.
Adenocarcinoma, Follicular
Increased plasminogen activator and type IV collagenase activity in invasive follicular thyroid carcinoma cells.
Perfluorooctanoic Acid Enhances Invasion of Follicular Thyroid Carcinoma Cells Through NF-?B and Matrix Metalloproteinase-2 Activation.
Adenoma
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Analyses of matrix metalloproteinases and their inhibitors in cyst fluid of serous ovarian tumors.
Cardiac Dysfunction in Association with Increased Inflammatory Markers in Primary Aldosteronism.
CD147 expression in pituitary adenomas and its significance for clinical outcome.
Contributory role of 5-lipoxygenase and its association with angiogenesis in the promotion of inflammation-associated colonic tumorigenesis by cigarette smoking.
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer.
Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients.
Matrix metalloproteinase-2 expression correlates with cavernous sinus invasion in pituitary adenomas.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in colonic adenomas-adenocarcinomas.
Measuring gelatinase activity in colorectal cancer.
Role of matrix metalloproteinases in colorectal carcinogenesis.
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
The behavior of MMP-2, MMP-7, MMP-9 and their inhibitors TIMP-1, TIMP-2 in adenoma-colorectal cancer sequence.
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence.
[Expression of MMP-2, HIF-1alpha and VEGF in Colon Adenoma and Colon Cancer.]
[Relationship of the disturbed balance between matrix metalloproteinases and their tissue inhibitors and the invasion of malignant salivary gland tumours]
[Role of matrix metalloproteinases-9, 2 and their inhibitor-TIMP-1, 2 in invasive pituitary adenomas biological behavior]
[Study of type I and IV collagenase activity in human thyroid diseases]
Adenoma, Oxyphilic
Matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in sera and urine of patients with renal carcinoma.
Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma.
Adenoma, Pleomorphic
Comparative Role of Matrixins in Diagnostics of Parotid Gland Tumors.
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1 and TIMP-2 in the epithelium and stroma of salivary gland pleomorphic adenomas.
[The expression of matrix metalloproteinases and their tissue inhibitors in pleomorphic adenoma]
Adenoma, Villous
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in colonic adenomas-adenocarcinomas.
Adenomatous Polyps
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
Adenomyoma
[The expression of moesin, p21-activated kinase 4 (PAK 4), matrix metalloproteinases (MMP 2, MMP 9), and CD34 in the eutopic and ectopic endometrium in adenomyosis].
Adenomyosis
Differential immunohistochemical expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in cow uteri with adenomyosis during follicular phase.
Effect of matrix metalloproteinase promoter polymorphisms on endometriosis and adenomyosis risk: evidence from a meta-analysis.
Expression of Cyclooxygenase-2 and Matrix Metalloproteinase-2 in Adenomyosis and Endometrial Polyps and its Correlation With Angiogenesis.
Increased expression of p21-activated kinase 4 in adenomyosis and its regulation of matrix metalloproteinase-2 and -9 in endometrial cells.
Increased invasion activity of endometrial stromal cells and elevated expression of matrix metalloproteinase messenger RNA in the uterine tissues of mice with experimentally induced adenomyosis.
Increased matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 secretion but unaffected invasiveness of endometrial stromal cells in adenomyosis.
Matrix Metalloproteinase-2 and -9 Expression Correlated with Angiogenesis in Human Adenomyosis.
Polymorphisms in the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 and the risk of human adenomyosis.
[Expression of matrix metalloproteinase and tissue inhibitor of metalloproteinase in adenomyosis]
[Study on the association of SNPs of MMP-2 and TIMP-2 genes with the risk of endometriosis and adenomyosis]
[The expression of moesin, p21-activated kinase 4 (PAK 4), matrix metalloproteinases (MMP 2, MMP 9), and CD34 in the eutopic and ectopic endometrium in adenomyosis].
Adrenal Cortex Neoplasms
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Aggressive Periodontitis
Human neutrophil gelatinase and associated lipocalin in adult and localized juvenile periodontitis.
Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: correlation with periodontal disease activity in adult and juvenile periodontitis.
Matrix metalloproteinase-2, -9, and -12 gene polymorphisms in generalized aggressive periodontitis.
Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients.
MMP-2, MMP-9 and TIMP-2 gene polymorphisms in Chinese patients with generalized aggressive periodontitis.
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
AIDS Dementia Complex
Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia.
Airway Obstruction
Induced sputum metalloproteinases and their inhibitors in relation to exhaled nitrogen oxide and sputum nitric oxides and other inflammatory cytokines in patients with chronic obstructive pulmonary disease.
[Expressions of cyclooxygenase-2 and matrix metalloproteinase-2 and airflow obstruction in patients with chronic obstructive pulmonary disease]
Albuminuria
Absence of Gelatinase (MMP-9) or Collagenase (MMP-13) Attenuates Adriamycin-Induced Albuminuria and Glomerulosclerosis.
Aldosterone induces albuminuria via matrix metalloproteinase-dependent damage of the endothelial glycocalyx.
Aortic Aneurysms, Chronic Kidney Disease and Metalloproteinases.
Association of the cystatin C/creatinine ratio with the renally cleared hormones parathyroid hormone (PTH) and brain natriuretic peptide (BNP) in primary care patients: a cross-sectional study.
Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease.
Markers of Glomerular and Tubular Damage in the Early Stage of Kidney Disease in Type 2 Diabetic Patients.
Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study.
Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy.
Renal biomarkers for the prediction of cardiovascular disease.
Role of matrix metalloproteinase-9 in chronic kidney disease: a new biomarker of resistant albuminuria.
The association between methylation levels of targeted genes and albuminuria in patients with early diabetic kidney disease.
Urinary matrix metalloproteinase activities: biomarkers for plaque angiogenesis and nephropathy in diabetes.
Urinary matrix metalloproteinase-8 and -9 activities in type 2 diabetic subjects: A marker of incipient diabetic nephropathy?
Alveolar Bone Loss
A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats.
Atorvastatin decreases bone loss, inflammation and oxidative stress in experimental periodontitis.
Chemically-Modified Curcumin 2.24: A Novel Systemic Therapy for Natural Periodontitis in Dogs.
Effects of formaldehyde on VEGF, MMP2, and Osteonectin levels in periodontal membrane and alveolar bone in the rats.
Gelatinases and extracellular matrix metalloproteinase inducer are associated with cyclosporin-A-induced attenuation of periodontal degradation in rats.
Alzheimer Disease
Activated isoforms of MMP-2 are induced in U87 human glioma cells in response to beta-amyloid peptide.
Concentrations of Matrix Metalloproteinases and their Tissue Inhibitors in the Cerebrospinal Fluid of Patients with Alzheimer's Disease.
Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors.
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.
Investigation of Matrix Metalloproteinases, MMP-2 and MMP-9, in Plasma Reveals a Decrease of MMP-2 in Alzheimer's Disease.
Matrix Metalloproteinases Are Associated With Increased Blood-Brain Barrier Opening in Vascular Cognitive Impairment.
Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer's disease, and epilepsy.
MMP-2, -3 and -9 levels and activity are not related to Abeta load in the frontal cortex in Alzheimer's disease.
Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer's Disease.
Proteolysis of A beta peptide from Alzheimer disease brain by gelatinase A.
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Ameloblastoma
Ameloblastic neoplasia spectrum: a cross-sectional study of MMPS expression and proliferative activity.
Comparison of osteoclastogenesis and local invasiveness of ameloblastoma and keratocystic odontogenic tumor.
Discrimination of ameloblastomas from odontogenic keratocysts by cytokine levels and gelatinase species of the intracystic fluids.
Elevated hydrostatic pressure promotes ameloblastoma cell invasion through upregulation of MMP-2 and MMP-9 expression via Wnt/?-catenin signalling.
Epigenetic regulation of matrix metalloproteinase expression in ameloblastoma.
Expression and role of metalloproteinase-2 and endogenous tissue regulator in ameloblastoma.
Expression of osteonectin/secreted protein acidic and rich in cysteine and matrix metalloproteinases in ameloblastoma.
Expression of RECK and matrix metalloproteinase-2 in ameloblastoma.
Hypoxia and proangiogenic proteins in human ameloblastoma.
Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
Immunohistochemical detection of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in ameloblastomas.
Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity.
Presence of Myofibroblasts and Expression of Matrix Metalloproteinase-2 (MMP-2) in Ameloblastomas Correlate with Rupture of the Osseous Cortical.
Relative expression of ?-smooth muscle actin and matrix metalloproteinases-2 in ameloblastoma of a black African sub-population.
Suppression of local invasion of ameloblastoma by inhibition of matrix metalloproteinase-2 in vitro.
Tissue inhibitor of metalloproteinase-2 inhibits ameloblastoma growth in a new mouse xenograft disease model.
[Association of matrix metalloproteinase-2 activity with cell proliferation and growth in ameloblastoma]
Amyloidosis
Doxycycline decreases amyloidogenic light chain-induced autophagy in isolated primary cardiac myocytes.
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Amyotrophic Lateral Sclerosis
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Anaplasia
High levels of messenger RNAs for tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in primary breast carcinomas are associated with development of distant metastases.
Aneurysm
A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.
A reproducible swine model of a surgically created saccular thoracic aortic aneurysm.
Activation of Endocannabinoid System Is Associated with Persistent Inflammation in Human Aortic Aneurysm.
Aortic Aneurysms, Chronic Kidney Disease and Metalloproteinases.
Arterial wall degeneration plus hemodynamic insult cause arterial wall remodeling and nascent aneurysm formation at specific sites in dogs.
ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway.
Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats.
Chemokines induce matrix metalloproteinase-2 through activation of epidermal growth factor receptor in arterial smooth muscle cells.
Combining two potential causes of metalloproteinase secretion causes abdominal aortic aneurysms in rats: a new experimental model.
Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome.
Early Increased MT1-MMP Expression and Late MMP-2 and MMP-9 Activity during Angiotensin II Induced Aneurysm Formation.
Effects of deletion of the tissue inhibitor of matrix metalloproteinases-1 gene on the progression of murine thoracic aortic aneurysms.
Erythropoietin increases circulating endothelial progenitor cells and reduces the formation and progression of cerebral aneurysm in rats.
Expression of matrix metalloproteinases and their inhibitors in aneurysms and normal aorta.
Expression of MMP-2, MMP-9, and NGAL in Tissue and Serum of Patients with Vascular Aneurysms and Their Modulation by Statin Treatment: A Pilot Study.
Gelatinase activity and the occurrence of cerebral aneurysms.
Genes predisposing to rapid aneurysm growth.
Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis.
Heterogeneity of tensile strength and matrix metalloproteinase activity in the wall of abdominal aortic aneurysms.
Hypoxia-inducible factor 1 in clinical and experimental aortic aneurysm disease.
Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2.
In situ localization and quantification of seventy-two-kilodalton type IV collagenase in aneurysmal, occlusive, and normal aorta.
Increased matrix metalloproteinase 2 expression in vascular smooth muscle cells cultured from abdominal aortic aneurysms.
Increased PAI-1 in Females Compared to Males is Protective for Abdominal Aortic Aneurysm Formation in a Rodent Model.
Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm.
Influence of elastin-derived peptides on metalloprotease production in endothelial cells.
Inhibition of Aneurysm Progression by Direct Renin Inhibition in a Rabbit Model.
Interference of doxycycline pretreatment in a model of abdominal aortic aneurysms.
Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall.
Marimastat inhibits elastin degradation and matrix metalloproteinase 2 activity in a model of aneurysm disease.
Matrix metalloproteinase activity in thoracic aortic aneurysms associated with bicuspid and tricuspid aortic valves.
Matrix metalloproteinase and tissue inhibitor expression in atherosclerotic and nonatherosclerotic thoracic aortic aneurysms.
Matrix metalloproteinase-2: the forgotten enzyme in aneurysm pathogenesis.
Matrix metalloproteinases 2 and 9 in human atherosclerotic and non-atherosclerotic cerebral aneurysms.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm.
Matrix metalloproteinases in ascending aortic aneurysms: bicuspid versus trileaflet aortic valves.
Matrix metalloproteinases in the aneurysm wall of patients treated with low-dose doxycycline.
Matrix Metalloproteinases in Vascular Disease - A Potential Therapeutic Target?
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells.
MMP inhibition in abdominal aortic aneurysms. Rationale for a prospective randomized clinical trial.
MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms.
MR imaging of iron phagocytosis in intraluminal thrombi of abdominal aortic aneurysms in humans.
Phyto-Derived Products as Matrix Metalloproteinases Inhibitors in Cardiovascular Diseases.
Plasma matrix metalloproteinase levels do not predict tissue levels in abdominal aortic aneurysms suitable for elective repair.
Presence of Chlamydia pneumoniae in abdominal aortic aneurysms is not associated with increased activity of matrix metalloproteinases.
Recombinant Interleukin-19 Suppresses the Formation and Progression of Experimental Abdominal Aortic Aneurysms.
Role of estrogen deficiency in the formation and progression of cerebral aneurysms. Part I: experimental study of the effect of oophorectomy in rats.
Role of matrix metalloproteinases (MMPs) and MMP inhibitors on intracranial aneurysms: a review article.
Role of matrix metalloproteinases in abdominal aortic aneurysms.
Role of TIMP-1 and TIMP-2 in the progression of cerebral aneurysms.
SDF-1?/CXCR4 Pathway Mediates Hemodynamics-Induced Formation of Intracranial Aneurysm by Modulating the Phenotypic Transformation of Vascular Smooth Muscle Cells.
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Smooth muscle phenotypic modulation is an early event in aortic aneurysms.
Systemic Administration of Ribbon-type Decoy Oligodeoxynucleotide Against Nuclear Factor ?B and Ets Prevents Abdominal Aortic Aneurysm in Rat Model.
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.
The expression and localization of membrane type-1 matrix metalloproteinase in human abdominal aortic aneurysms.
The protective effect of puerarin on angiotensin II-induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways.
The role of estrogen in the formation of experimental abdominal aortic aneurysm.
The role of MMP-2 and MMP-9 polymorphisms in sporadic intracranial aneurysms.
Time-dependent and site-dependent morphological changes in rupture-prone arteries: ovariectomized rat intracranial aneurysm model.
Ubiquitous elevation of matrix metalloproteinase-2 expression in the vasculature of patients with abdominal aneurysms.
Vascular aneurysms: a perspective.
Vascular extracellular matrix remodeling in cerebral aneurysms.
Aneurysm, Dissecting
Ang II enhances noradrenaline release from sympathetic nerve endings thus contributing to the up-regulation of metalloprotease-2 in aortic dissection patients' aorta wall.
Association of MMP-2 gene haplotypes with thoracic aortic dissection in chinese han population.
Association of smooth muscle cell phenotypes with extracellular matrix disorders in thoracic aortic dissection.
Autonomic remodeling may be responsible for decreased incidence of aortic dissection in STZ-induced diabetic rats via down-regulation of matrix metalloprotease 2.
Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections.
Local upregulation of interleukin-1 beta in aortic dissecting aneurysm: correlation with matrix metalloproteinase-2, 9 expression and biomechanical decrease.
MMP-2 gene polymorphisms are associated with type A aortic dissection and aortic diameters in patients.
Plasma levels of metalloproteinases-9 and -2 in the acute and subacute phases of type A and type B aortic dissection.
Serum levels of matrix metalloproteinases -1,-2,-3 and -9 in thoracic aortic diseases and acute myocardial ischemia.
The expression and significance of IL-6, IFN-?, SM22?, and MMP-2 in rat model of aortic dissection.
The expression of the BRM and MMP2 genes in thoracic aortic aneurysm and aortic dissection.
The prominent expression of plasma matrix metalloproteinase-8 in acute thoracic aortic dissection.
Up-regulation of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase were coupled with that of type I procollagen in granulation tissue response after the onset of aortic dissection.
[Effect of bilateral superior cervical sympathetic ganglion occlusion on pathological process of aortic dissection and its mechanism].
Aneurysm, Ruptured
Activation of Extracellular signal-Related Kinase in abdominal aortic aneurysm.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm.
SDF-1?/CXCR4 Pathway Mediates Hemodynamics-Induced Formation of Intracranial Aneurysm by Modulating the Phenotypic Transformation of Vascular Smooth Muscle Cells.
Angina Pectoris
Enhanced cardiac production of matrix metalloproteinase-2 and -9 and its attenuation associated with pravastatin treatment in patients with acute myocardial infarction.
Angina, Stable
CD100 modulates cytotoxicity of CD8+ T cells in patients with acute myocardial infarction.
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Elevated circulating levels of matrix metalloproteinase-9 and -2 in patients with symptomatic coronary artery disease.
Expressions and clinical significance of factors related to acute coronary syndrome.
Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina.
Metalloproteinases-2, -9 and TIMP-1 expression in stable and unstable coronary plaques undergoing PCI.
New insights into molecular mechanisms of diffuse coronary ectasiae: a possible role for VEGF.
Angina, Unstable
CD100 modulates cytotoxicity of CD8+ T cells in patients with acute myocardial infarction.
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina.
Serum profiles of matrix metalloproteinases and their tissue inhibitor in patients with acute coronary syndromes. The effects of short-term atorvastatin administration.
Angiofibroma
Metalloproteinases in juvenile angiofibroma--a collagen rich tumor.
TGF-beta enhances MMP-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex.
Ankylosis
An extract from Myracrodruon urundeuva inhibits matrix mineralization in human osteoblasts.
Anthrax
Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.
Present-day conservative treatment retinopathy of prematurity.
Antiphospholipid Syndrome
Higher levels of plasma matrix metalloproteinase-2 are associated with a significantly increased risk of arterial thrombosis in patients with the antiphospholipid syndrome.
Aortic Aneurysm
A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.
Amelioration of salvianolic acid C on aortic structure in apolipoprotein E-deficient mice treated with angiotension II.
Angiotensin II induces an increase in MMP-2 expression in idiopathic ascending aortic aneurysm via AT1 receptor and JNK pathway.
ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway.
Characterization of serum matrix metalloproteinase 2/9 levels in patients with ascending aortic aneurysms.
Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms.
Effect of miR-21 on rat thoracic aortic aneurysm model by regulating the expressions of MMP-2 and MMP-9.
Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic aneurysms.
Enhanced invasive properties exhibited by smooth muscle cells are associated with elevated production of MMP-2 in patients with aortic aneurysms.
In situ localization and quantification of mRNA for 92-kD type IV collagenase and its inhibitor in aneurysmal, occlusive, and normal aorta.
In situ localization and quantification of seventy-two-kilodalton type IV collagenase in aneurysmal, occlusive, and normal aorta.
Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections.
Localization of matrix metalloproteinase 2 within the aneurysmal and normal aortic wall.
Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve.
MCP-1, ICAM-1 and VCAM-1 are present in early aneurysmal dilatation in experimental rats.
Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells.
MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms.
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
The protective effect of puerarin on angiotensin II-induced aortic aneurysm formation by the inhibition of NADPH oxidase activation and oxidative stress-triggered AP-1 signaling pathways.
Aortic Aneurysm, Abdominal
Activation of Extracellular signal-Related Kinase in abdominal aortic aneurysm.
Activity of matrix metalloproteinase-2 and -9 in abdominal aortic aneurysms. Relation to size and rupture.
An uncommon case of arterial aneurysms association with high plasma levels of Matrix Metalloproteinase-9 and Neutrophil Gelatinase-Associated Lipocalin.
Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice.
Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall.
Decreased tissue inhibitor of metalloproteinase-2/matrix metalloproteinase ratio in the acute phase of aortic dissection.
Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice.
Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase.
Early MT-1 MMP expression following elastase exposure is associated with increased cleaved MMP-2 activity in experimental rodent aortic aneurysms.
Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic aneurysms.
Evaluation of the levels of metalloproteinsase-2 in patients with abdominal aneurysm and abdominal hernias.
Genes predisposing to rapid aneurysm growth.
Hypoxia in Abdominal Aortic Aneurysm Supports a Role for HIF-1? and Ets-1 as Drivers of Matrix Metalloproteinase Upregulation in Human Aortic Smooth Muscle Cells.
Immunohistochemical expression of metalloproteinases MMP-2 and MMP-9 in abdominal aortic aneurysms: correlation with symptoms and aortic diameter.
Increased matrix metalloproteinase 2 expression in vascular smooth muscle cells cultured from abdominal aortic aneurysms.
Matrix metalloproteinase 2 is suppressed by trapidil, a CD40-CD40 ligand pathway inhibitor, in human abdominal aortic aneurysm wall.
Matrix metalloproteinase 2 polymorphisms in a caucasian population with abdominal aortic aneurysm.
Matrix metalloproteinase-2 gene variants and abdominal aortic aneurysm.
Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms.
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation.
Overexpression of TIMP-2 mediated by recombinant adenovirus in rat abdominal aorta inhibits extracellular matrix degradation.
Porphyromonas gingivalis promotes murine abdominal aortic aneurysms via matrix metalloproteinase-2 induction.
Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Spatial differences of matrix metalloproteinase-2 and matrix metalloproteinase-9 within abdominal aortic aneurysm wall and intraluminal thrombus.
Transgenic expression of matrix metalloproteinase-2 induces coronary artery ectasia.
[Analysis of tissue inhibitor of metalloproteinase-2 gene polymorphisms in a caucasian population with abdominal aortic aneurysms]
Aortic Aneurysm, Thoracic
A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.
Angiotensin II increases matrix metalloproteinase 2 expression in human aortic smooth muscle cells via AT1R and ERK1/2.
Angiotensin II Induces an Increase in Matrix Metalloproteinase 2 Expression in Aortic Smooth Muscle Cells of Ascending Thoracic Aortic Aneurysms Through JNK, ERK1/2, and p38 MAPK Activation.
Differential expression of MMP-2, MMP-9 and TIMP proteins in thoracic aortic aneurysm - comparison with and without bicuspid aortic valve: a meta-analysis.
Divergent Role of Matrix Metalloproteinase 2 in Pathogenesis of Thoracic Aortic Aneurysm.
Effect of miR-21 on rat thoracic aortic aneurysm model by regulating the expressions of MMP-2 and MMP-9.
Elevation of ADAM10, ADAM17, MMP-2 and MMP-9 expression with media degeneration features CaCl2-induced thoracic aortic aneurysm in a rat model.
Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.
Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.
Matrix metalloproteinase activity in thoracic aortic aneurysms associated with bicuspid and tricuspid aortic valves.
Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation.
The expression of the BRM and MMP2 genes in thoracic aortic aneurysm and aortic dissection.
Aortic Diseases
Matrix metalloproteinases in ascending aortic aneurysms: bicuspid versus trileaflet aortic valves.
Aortic Valve Stenosis
A Possible Early Biomarker for Bicuspid Aortopathy: Circulating Transforming Growth Factor ?-1 to Soluble Endoglin Ratio.
Alterations in circulating activin A, GDF-15, TGF-beta3 and MMP-2, -3, and -9 during one year of left ventricular reverse remodelling in patients operated for severe aortic stenosis.
Chemically modified tetracyclines (CMT-3 and CMT-8) enable control of the pathologic remodellation of human aortic valve stenosis via MMP-9 and VEGF inhibition.
Circulating matrix metalloproteinase patterns in association with aortic dilatation in bicuspid aortic valve patients with isolated severe aortic stenosis.
Expression and activity of matrix metalloproteinase-2 in calcific aortic stenosis.
Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis.
MMP-2/TIMP-2/TIMP-4 versus MMP-9/TIMP-3 in transition from compensatory hypertrophy and angiogenesis to decompensatory heart failure.
Appendicitis
A local imbalance between MMP and TIMP may have an implication on the severity and course of appendicitis.
Arrhythmias, Cardiac
Suppression of ?1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats.
Arteriosclerosis
Binding of 92 kDa and 72 kDa progelatinases to insoluble elastin modulates their proteolytic activation.
MMP-2 expression is associated with rapidly proliferative arteriosclerosis in the flexor tenosynovium and pain severity in carpal tunnel syndrome.
Arteriovenous Fistula
Arterial enlargement in response to high flow requires early expression of matrix metalloproteinases to degrade extracellular matrix.
Expression of Hypoxia Inducible Factor-1alpha, Macrophage Migration Inhibition Factor, Matrix Metalloproteinase-2 and ?9, and Their Inhibitors in Hemodialysis Grafts and Arteriovenous Fistulas.
Increased expression of HIF-1alpha, VEGF-A and its receptors, MMP-2, TIMP-1, and ADAMTS-1 at the venous stenosis of arteriovenous fistula in a mouse model with renal insufficiency.
Serum metalloproteinases MMP-2, MMP-9, and metalloproteinase tissue inhibitors in patients are associated with arteriovenous fistula maturation.
The rat femoral arteriovenous fistula model: increased expression of matrix metalloproteinase-2 and -9 at the venous stenosis.
Arteriovenous Malformations
Elevated Expression of Matrix Metalloproteinase-9 not Matrix Metalloproteinase-2 Contributes to Progression of Extracranial Arteriovenous Malformation.
Expression of osteopontin, matrix metalloproteinase-2 and -9 proteins in vascular instability in brain arteriovenous malformation.
Imbalance of matrix metalloproteinase-9 and matrix metalloproteinase tissue inhibitor-1 may contribute to hemorrhage in cerebellar arteriovenous malformations.
Arteritis
Elevated levels of 92-kd type IV collagenase (matrix metalloproteinase 9) in giant cell arteritis.
Elevated serum levels of matrix metalloproteinase-9 (MMP-9) in Kawasaki disease.
Gelatinase expression and proteolytic activity in giant-cell arteritis.
Metalloproteinase-2 and -9 in giant cell arteritis: involvement in vascular remodeling.
Arthralgia
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
Arthritis
A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging.
A correlation between knee cartilage degradation observed by arthroscopy and synovial proteinases activities.
A novel matrix metalloproteinase 2 (MMP2) terminal hemopexin domain mutation in a family with multicentric osteolysis with nodulosis and arthritis with cardiac defects.
Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis.
Arthritis induced immunologically with cationic amidated bovine serum albumin in the guinea pig. A morphological and biochemical study on the destruction of articular cartilage.
Assessment of the clinical significance of gelatinase activity in patients with juvenile idiopathic arthritis using quantitative protein substrate zymography.
Canine TIMP-2: purification, characterization and molecular detection.
Cathepsin B and cystatin C play an inflammatory role in gouty arthritis of the knee.
Changes in MMP-2 and -9 activity and MMP-8 reactivity after amphotericin B induced synovitis and treatment with bufexamac.
Clinical Radiological and Molecular Profile of a Patient Affected With Multicentric Osteolysis Nodulosis and Arthropathy.
Clinical significance of gelatinases in septic arthritis of native and replaced knees.
Clitoria ternatea flower petals: Effect on TNFR1 neutralization via downregulation of synovial matrix metalloproteases.
Collagen type III content of the long head of the biceps tendon as an indicator of glenohumeral arthritis.
Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking.
Effects of high molecular weight hyaluronic acid on induced arthritis of the temporomandibular joint in rats.
Elevated plasma stromelysin levels in arthritis.
Expression levels and association of gelatinases MMP-2 and MMP-9 and collagenases MMP-1 and MMP-13 with VEGF in synovial fluid of patients with arthritis.
Expression levels of matrix metalloproteinase (MMP)-9 and its specific inhibitor TIMP-1, in septic and aseptic arthritis of the knee.
Generation of glycosylated remnant epitopes from human collagen type II by gelatinase B.
Infliximab therapy does not modify MMP-2 and MMP-9 serum concentrations in chronic arthritis.
Involvement of 15-lipoxygenase in the inflammatory arthritis.
Isolation and characterization of human monoclonal antibodies specific to MMP-1A, MMP-2 and MMP-3.
Levels of Selected Matrix Metalloproteinases, Their Inhibitors in Saliva, and Oral Status in Juvenile Idiopathic Arthritis Patients vs. Healthy Controls.
Liposomes encapsulated dimethyl curcumin regulates dipeptidyl peptidase I activity, gelatinase release and cell cycle of spleen lymphocytes in-vivo to attenuate collagen induced arthritis in rats.
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Matrix metalloproteinase-2 contributes to joint destruction in group B streptococcus-induced arthritis.
Matrix metalloproteinases 2 and 9 activity in bovine synovial fluids.
Matrix metalloproteinases: role in arthritis.
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above.
Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail.
Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis.
Spectrum of common and uncommon causes of knee joint hyaline cartilage degeneration and their key imaging features.
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
The clinical significance of gelatinase B in gouty arthritis of the knee.
The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis.
The significance of altered gelatinase expression in the synovium of patient with arthritic effusions.
Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter.
Zymographic analysis of latent and activated forms of matrix metalloproteinase-2 and -9 in synovial fluid: correlation to polymorphonuclear leukocyte infiltration and in response to infection.
Arthritis, Experimental
Effect of a derivatized tetrapeptide from lactoferrin on nitric oxide mediated matrix metalloproteinase-2 production by synovial fibroblasts in collagen-induced arthritis in rats.
Penta-acetyl Geniposide Suppresses Migration, Invasion, and Inflammation of TNF-?-Stimulated Rheumatoid Arthritis Fibroblast-Like Synoviocytes Involving Wnt/?-Catenin Signaling Pathway.
Arthritis, Gouty
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
The clinical significance of gelatinase B in gouty arthritis of the knee.
Urokinase-type plasminogen activator, receptor, and inhibitor correlating with gelatinase-B (MMP-9) contribute to inflammation in gouty arthritis of the knee.
Arthritis, Infectious
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Determination of MMP-2 and -9 activities in synovial fluid of horses with osteoarthritic and arthritic joint diseases using gelatin zymography and immunocapture activity assays.
Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking.
Matrix metalloproteinase-2 contributes to joint destruction in group B streptococcus-induced arthritis.
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Prepatellar bursitis due to Brucella abortus: case report and analysis of the local immune response.
Relative expression of matrix metalloproteinase-2 and -9 in synovial fluid from healthy calves and calves with experimentally induced septic arthritis.
Arthritis, Juvenile
Assessment of the clinical significance of gelatinase activity in patients with juvenile idiopathic arthritis using quantitative protein substrate zymography.
Clinical Radiological and Molecular Profile of a Patient Affected With Multicentric Osteolysis Nodulosis and Arthropathy.
Levels of Selected Matrix Metalloproteinases, Their Inhibitors in Saliva, and Oral Status in Juvenile Idiopathic Arthritis Patients vs. Healthy Controls.
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Arthritis, Psoriatic
Gelatinase expression and activity in the synovium and skin of patients with erosive psoriatic arthritis.
MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in patients with rheumatoid arthritis and psoriatic arthritis.
Possible molecular mechanisms to account for the involvement of tryptase in the pathogenesis of psoriasis.
Arthritis, Rheumatoid
A trypsin sensitive stromelysin isolated from rheumatoid synovial fluid is an activator for matrix metalloproteinases.
Activation of progelatinase B in synovial fluids of patients with rheumatoid arthritis, with reference to stromelysin-1 and tissue inhibitor of matrix metalloproteinase-1.
Association Study of Matrix Metalloproteinases Gene Polymorphisms with Susceptibility to Rheumatoid Arthritis: A Meta-Analysis.
Autoactivation profiles of calcium-dependent matrix metalloproteinase-2 and -9 in inflammatory synovial fluid: effect of pyrophosphate and bisphosphonates.
Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis.
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Delphinidin suppresses PMA-induced MMP-9 expression by blocking the NF-?B activation through MAPK signaling pathways in MCF-7 human breast carcinoma cells.
Differential regulation of matrix metalloproteinase 2 and matrix metalloproteinase 9 by activated protein C: relevance to inflammation in rheumatoid arthritis.
Elevated circulatory MMP-2 and MMP-9 levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus.
Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2.
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in rheumatoid synovium.
Expression of matrix metalloproteinase 9 (96-kd gelatinase B) in human rheumatoid arthritis.
Generation of glycosylated remnant epitopes from human collagen type II by gelatinase B.
Hydroxamate-based peptide inhibitors of matrix metalloprotease 2.
Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis.
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Involvement of 15-lipoxygenase in the inflammatory arthritis.
Liver X Receptor (LXR) regulates rheumatoid arthritis fibroblast-like synoviocytes invasiveness, MMP-2 activation, IL-6 and CXCL10.
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption.
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
MMP-2, MMP-9, TIMP-1 and TIMP-2 levels in patients with rheumatoid arthritis and psoriatic arthritis.
MMP-2, TNF-? and NLRP1 polymorphisms in Chinese patients with ankylosing spondylitis and rheumatoid arthritis.
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis: destruction from above.
Prepatellar bursitis due to Brucella abortus: case report and analysis of the local immune response.
Regulation of interleukin-1beta-induced chemokine production and matrix metalloproteinase 2 activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts.
Remnant epitopes, autoimmunity and glycosylation.
Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritis.
Suppression of adjuvant arthritis of rats by a novel matrix metalloproteinase-inhibitor.
Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.
Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in interleukin-1beta stimulated fibroblast-like synoviocytes.
The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.
The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis.
TNF-alpha-mediated expression of membrane-type matrix metalloproteinase in rheumatoid synovial fibroblasts.
[Polymorphism of gene promotor region for MMP-2 in rheumatoid arthritis]
Asbestosis
Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case-control study.
Asthma
Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration.
Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor.
Elevated serum matrix metalloprotease (MMP-2) as a candidate biomarker for stable COPD.
Enhancement of gelatinase activity during development of subepithelial fibrosis in a murine model of asthma.
Environmental arsenic exposure and sputum metalloproteinase concentrations.
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Highly Protective Association of MMP-2-1306C/T Promoter Polymorphism With Asthma in a North Indian Population: A Pilot Study.
Increased circulating 92 kDa matrix metalloproteinase (MMP-9) activity in exacerbations of asthma.
Increased release of matrix metalloproteinase-9 in the plasma of acute severe asthmatic patients.
Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma.
Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-?1 in airway fibroblasts in asthma.
Matrix metalloproteinase-9 in lung remodeling.
Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in sputum from patients with bronchial asthma.
Matrix metalloproteinases in the pathogenesis of asthma and COPD: implications for therapy.
MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7.
Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma.
Relationship between matrix production by bronchial fibroblasts and lung function and AHR in asthma.
Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13-Suppressed Elastin in Airway Fibroblasts in Asthma.
Role of metalloproteinases MMP-2 in asthma.
Significant Association of MMP2 Promoter Genotypes to Asthma Susceptibility in Taiwan.
Soluble membrane-type 1 matrix metalloproteinase (MT1-MMP) and gelatinase A (MMP-2) in induced sputum and bronchoalveolar lavage fluid of human bronchial asthma and bronchiectasis.
Tachykinins induce gelatinase production by guinea pig alveolar macrophages: involvement of NK2 receptors.
[Effect of triggering receptor expressed on myeloid cells 2 overexpression on airway inflammation and remodeling in mice with allergic asthma].
[Effects of Fritillariae Cirrhosae Bulbus on MMP-2,MMP-9 and TIMP-1 in murine asthma model].
[Regulatory effects of inhaled steroids on expression of matrix metalloproteinase-9 and its inhibitor in asthmatic rats]
Astrocytoma
An extracellular proteasome-like structure from C6 astrocytoma cells with serine collagenase IV activity and metallo-dependent activity on alpha-casein and beta-insulin.
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases.
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.
Evaluation of invasiveness of astrocytoma using (1)H-magnetic resonance spectroscopy: correlation with expression of matrix metalloproteinase-2.
Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behaviour of brain tumour cells in vitro.
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas.
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Expression of timp-1, timp-2, 72-kda and 92-kda type-iv collagenase transcripts in human astrocytoma cell-lines - correlation with astrocytoma cell invasiveness.
Expression, association with clinicopathological features and prognostic potential of CEP55, p-Akt, FoxM1 and MMP-2 in astrocytoma.
Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility.
l-Glutamate in Middlebrook 7H9 culture medium upregulates matrix metalloproteinase-2 secretion from human astrocytoma cells.
Localization of gelatinase activities in glioma tissues by film in situ zymography.
Loss of Inhibitor of Growth (ING-4) Is Implicated in the Pathogenesis and Progression of Human Astrocytomas.
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Matrix metalloproteinase expression in childhood astrocytomas.
Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas.
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Promotion of astrocytoma cell invasion by micro RNA-22 targeting of tissue inhibitor of matrix metalloproteinase-2.
Serum proteolytic activity during the growth of C6 astrocytoma.
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
The Evaluation of AREG, MMP-2, CHI3L1, GFAP, and OPN Serum Combined Value in Astrocytic Glioma Patients' Diagnosis and Prognosis.
The importance of cell density in the interpretation of growth factor effects on collagenase IV activity release and extracellular matrix production from C6 astrocytoma cells.
The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.
Therapeutic effects of dasatinib in mouse model of multiple sclerosis.
Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma.
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
Ataxia
Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma.
Atherosclerosis
(-)-Epicatechin gallate blocks the development of atherosclerosis by regulating oxidative stress in vivo and in vitro.
A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging.
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates.
Angiotensin II induces MMP-2 in a p47phox-dependent manner.
Anti-inflammatory effects of atorvastatin: modulation by the T-786C polymorphism in the endothelial nitric oxide synthase gene.
Atherosclerosis and the protective role played by different proteins in apolipoprotein E-deficient mice.
Biomarkers and location of atherosclerosis: Matrix metalloproteinase-2 may be related to intracranial atherosclerosis.
Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis.
Chinese Yellow Wine and Red Wine Inhibit Matrix Metalloproteinase-2 and Improve Atherosclerotic Plaque in LDL Receptor Knockout Mice.
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Coexpression of cyclooxygenase-2 and matrix metalloproteinases in human aortic atherosclerotic lesions.
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Crosstalk Between Enzyme Matrix Metalloproteinases 2 and 9 and Regulatory T Cell Immunity in the Global Burden of Atherosclerosis.
Delphinidin suppresses PMA-induced MMP-9 expression by blocking the NF-?B activation through MAPK signaling pathways in MCF-7 human breast carcinoma cells.
Development of an aptamer-conjugated fluorescent nanoprobe for MMP2.
Distribution profiles of membrane Type-1 matrix metalloproteinase (MT1-MMP), matrix metalloproteinase-2 (MMP-2) and cyclooxygenase-2 (COX-2) in rabbit atherosclerosis: comparison with plaque instability analysis.
Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice.
Emodin inhibits tumor necrosis factor-?-induced migration and inflammatory responses in rat aortic smooth muscle cells.
Facial amphipathic deoxycholic acid-modified polyethyleneimine for efficient MMP-2 siRNA delivery in vascular smooth muscle cells.
Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis.
Ginkgetin ameliorates experimental atherosclerosis in rats.
Heparin inhibits the production of matrix metalloproteinase-2 and improves atherosclerosis in LDL receptor-deficient mice.
High glucose alters matrix metalloproteinase expression in two key vascular cells: potential impact on atherosclerosis in diabetes.
High glucose enhance expression of matrix metalloproteinase-2 in smooth muscle cells.
Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina.
Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation.
Immortalization of human aortic smooth muscle cells with origin-minus simian virus 40 DNA.
Impact of matrix metalloproteinases on atherosclerosis.
Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions.
Increased MMP-2 in healthy postmenopausal women.
Influence of elastin-derived peptides on metalloprotease production in endothelial cells.
Inhibitory effect of recombinant human CXCL8(3-72)K11R/G31P on atherosclerotic plaques in a mouse model of atherosclerosis.
Laminar high shear stress up-regulates type IV collagen synthesis and down-regulates MMP-2 secretion in endothelium. A quantitative analysis.
Markers of increased atherosclerotic risk in patients with chronic kidney disease: a preliminary study.
Matrix Metalloproteinase 2 and Osteoprotegrin as New Markers of Increased Atherosclerotic Risk in Egyptian Patients with Chronic Kidney Disease.
Matrix metalloproteinase-2 on activated platelets triggers endothelial PAR-1 initiating atherosclerosis.
Matrix metalloproteinases 2 and 9 in human atherosclerotic and non-atherosclerotic cerebral aneurysms.
Matrix Metalloproteinases and Subclinical Atherosclerosis in Chronic Kidney Disease: A Systematic Review.
Matrix Metalloproteinases in Vascular Disease - A Potential Therapeutic Target?
Methylation in the matrix metalloproteinase-2 gene is associated with cerebral ischemic stroke.
MMP-2 and MMP-9 are prominent matrix metalloproteinases during atherosclerosis development in the Ldlr(-/-)Apob(100/100) mouse.
Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9.
Platelet-derived growth factor-BB induces matrix metalloproteinase-2 expression and rat vascular smooth muscle cell migration via ROCK and ERK/p38 MAPK pathways.
Possible Mechanisms of Di(2-ethylhexyl) Phthalate-Induced MMP-2 and MMP-9 Expression in A7r5 Rat Vascular Smooth Muscle Cells.
Pterostilbene Inhibits Vascular Smooth Muscle Cells Migration and Matrix Metalloproteinase-2 through Modulation of MAPK Pathway.
Rapid release of matrix metalloproteinase (MMP)-2 by thrombin in the rat aorta: modulation by protein tyrosine kinase/phosphatase.
Renal Denervation Promotes Atherosclerosis in Hypertensive Apolipoprotein E-Deficient Mice Infused with Angiotensin II.
Role of oncogene 24p3 neutrophil gelatinase-associated lipocalin (NGAL) in digestive system cancers.
Rosuvastatin inhibits MMP-2 expression and limits the progression of atherosclerosis in LDLR-deficient mice.
Silencing of long non-coding RNA H19 downregulates CTCF to protect against atherosclerosis by upregulating PKD1 expression in ApoE knockout mice.
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Synthesis of a beta-tetrapeptide analog as a mother compound for the development of matrix metalloproteinase-2-imaging agents.
Tanshinone IIA downregulates the CD40 expression and decreases MMP-2 activity on atherosclerosis induced by high fatty diet in rabbit.
The effect of doxycycline on atherogenesis in apoE-knockout mice.
The expression of CD40-CD40L and activities of matrix metalloproteinases in atherosclerotic rats.
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Thrombin-thrombomodulin activation of protein C facilitates the activation of progelatinase A.
Treatment of ?-thujaplicin counteracts di(2-ethylhexyl)phthalate (DEHP)-exposed vascular smooth muscle activation, inflammation and atherosclerosis progression.
Urokinase-type plasminogen activator and metalloproteinase-2 are independently related to the carotid atherosclerosis in haemodialysis patients.
[Effects of PPAR-gamma agonist and MMP-2 on formation of atherosclerosis plaque in rabbits]
[Impacts of atovastatin and tinidazole on cardiac muscle inflammation factors of tumor necrosis factor-?, interleukin-1 and metalloproteinase-2 of experimental rabbits with atherosclerosis and periodontitis].
[The expression of matrix metalloproteinase-2,9 on atherosclerosis in experimental rats by treatment of 2,3,4',5-tetrahydroxystilbene -2-0-beta-D glucoside].
Atrial Fibrillation
Ageing related down-regulation of myocardial connexin-43 and up-regulation of MMP-2 may predict propensity to atrial fibrillation in experimental animals.
Associations Between Neutrophil Gelatinase Associated Lipocalin, Neutrophil-to-Lymphocyte Ratio, Atrial Fibrillation and Renal Dysfunction in Chronic Heart Failure.
Associations of MMP-2, BAX, and Bcl-2 mRNA and Protein Expressions with Development of Atrial Fibrillation.
Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation.
Effects of amiodarone on electrical and structural remodeling induced in a canine rapid pacing-induced persistent atrial fibrillation model.
Impact of Biomarkers of Inflammation and Extracellular Matrix Turnover on the Outcome of Atrial Fibrillation Ablation: Importance of Matrix Matalloproteinase-2 as a Predictor of Atrial Fibrillation Recurrence.
Impact of matrix metalloproteinase-2 levels on long-term outcome following pharmacological or electrical cardioversion in patients with atrial fibrillation.
MMP-2 and TIMP-2 gene polymorphisms and susceptibility to atrial fibrillation in Chinese Han patients with hypertensive heart disease.
Oral direct renin inhibitor aliskiren reduces in vivo oxidative stress and serum matrix metalloproteinase-2 levels in patients with permanent atrial fibrillation.
The role of matrix metalloproteinase-2 in the treatment of atrial fibrillation recurrence after a radiofrequency modified maze procedure.
[Clinical on molecular basis of atrial fibrosis in patients with atrial fibrillation investigation]
Autoimmune Diseases
Changes of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in the serum of patients with autoimmune diseases: association with age and disease activity.
Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease.
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
T cell gelatinases mediate basement membrane transmigration in vitro.
Autoimmune Pancreatitis
Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels.
Azoospermia
Quantitative differences in matrix metalloproteinase (MMP)-2, but not in MMP-9, tissue inhibitor of metalloproteinase (TIMP)-1 or TIMP-2, in seminal plasma of normozoospermic and azoospermic patients.
Bacteremia
Association between the presence of enterococcal virulence factors gelatinase, hemolysin, and enterococcal surface protein and mortality among patients with bacteremia due to Enterococcus faecalis.
Bacterial and host factors affecting Pseudomonas aeruginosa colonization versus bacteremia in granulocytopenic patients.
[Virulence genes and bacteriocins in Enterococcus faecalis strains isolated from different clinical samples in Maule Region, Chile].
Bacterial Infections
Matrix metalloproteinase 2 of grass carp Ctenopharyngodon idella (CiMMP2) is involved in the immune response against bacterial infection.
Regulation of MMPs and TIMPs by IL-1beta during corneal ulceration and infection.
Bicuspid Aortic Valve Disease
Differential expression of MMP-2, MMP-9 and TIMP proteins in thoracic aortic aneurysm - comparison with and without bicuspid aortic valve: a meta-analysis.
Endothelial function and plasma matrix metalloproteinase-2 levels and their association with the size and elastic properties of the ascending aorta in first-degree relatives of bicuspid aortic valve patients.
Endothelial function, carotid-femoral stiffness, and plasma matrix metalloproteinase-2 in men with bicuspid aortic valve and dilated aorta.
Enlarged Size and Impaired Elastic Properties of the Ascending Aorta are Associated with Endothelial Dysfunction and Elevated Plasma Matrix Metalloproteinase-2 Level in Patients with Bicuspid Aortic Valve.
Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves.
Matrix metalloproteinase activity in thoracic aortic aneurysms associated with bicuspid and tricuspid aortic valves.
Matrix metalloproteinase-2 and -9 levels in patients with dilated ascending aorta and bicuspid aortic valve.
Matrix Metalloproteinase-2 Isoforms Differ within the Aortic Wall of Ascending Aortic Aneurysms Associated with Bicuspid Aortic Valve.
Nonstenotic bicuspid aortic valve is associated with elevated plasma asymmetric dimethylarginine.
The Role Matrix Metalloproteinases in the Production of Aortic Aneurysm.
Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation.
Biliary Atresia
Matrilysin (MMP-7) is a major matrix metalloproteinase upregulated in biliary atresia-associated liver fibrosis.
Blast Crisis
Matrix metalloproteinase production by bone marrow mononuclear cells from normal individuals and patients with acute and chronic myeloid leukemia or myelodysplastic syndromes.
[Angiogenesis in different clinical phases of chronic myeloid leukemia].
Blister
92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen.
A case of anaphylactoid purpura with multiple blister formation: possible pathophysiological role of gelatinase (MMP-9).
Altered expression of basement membrane proteins and their integrin receptors in lichen planus: possible pathogenetic role of gelatinases A and B.
Correlation between Tissue Characterization and Dynamic Expression of Matrix Metalloproteinase-2 and Its Tissue Inhibitor in Conjunctival Filtering Bleb of Rats.
Effect of Qingguangan on the expressions of MMP-2 and MMP-9 in filtering bleb after trabeculectomy in rabbits.
Exogenous Tissue Inhibitor of Metalloproteinase-2 Affects Matrix Metalloproteinase-2 Expression in Conjunctival Filtering Blebs and Bleb Scarring in Rats.
Increased expression of matrix metalloproteinase-2, matrix metalloproteinase-9 and matrix metalloproteinase-13 in lesional skin of bullous pemphigoid.
Influence of aging, localization, glucocorticoids and isotretinoin on matrix metalloproteases 2 (MMP-2) and 9 (MMP-9) in suction blister fluids.
Interleukin 1 alpha (IL-1 alpha) in human skin in vivo: lack of correlation to markers of collagen metabolism.
Matrix metalloproteinases (MMP-1, MMP-2, MMP-3 and MMP-9, and TIMP-1, TIMP-2 and TIMP-3) and markers for vascularization in functioning and non-functioning bleb capsules of glaucoma drainage implants.
Matrix- metalloproteinase -2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis.
MMP expression in leaking filtering blebs and tears after glaucoma filtering surgery.
Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts.
Possible involvement of gelatinase A (MMP2) and gelatinase B (MMP9) in toxic epidermal necrolysis or Stevens-Johnson syndrome.
Proteolytic enzymes in blister fluids from patients with dermatitis herpetiformis.
Topical synthetic inhibitor of matrix metalloproteinases delays epidermal regeneration of human wounds.
Bone Diseases
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
Bone Diseases, Metabolic
[Relationships between circulating matrix metalloproteinase-1, -2 and metalloproteinase-1 levels and bone biochemical markers and bone mineral density in Chinese postmenopausal women]
Bone Resorption
1alpha,25-dihydroxyvitamin D3 regulates the expression of membrane-type matrix metalloproteinase-1 in normal human osteoblast-like cells.
Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells.
Aseptic loosening in uncemented total hip arthroplasty in a canine model.
Basigin-2 upregulated by receptor activator of NF-?B ligand enhances lung cancer-induced osteolytic lesions.
Biphenyl sulfonylamino methyl bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption.
Circulating sRAGE in the diagnosis of osteolytic bone metastasis.
Effects of 17beta-estradiol and progesterone on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in rat osteoblasts.
Effects of 17beta-estradiol on the expression of matrix metalloproteinase-1, -2 and tissue inhibitor of metalloproteinase-1 in human osteoblast-like cell cultures.
Effects of 17beta-estradiol on the expression of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in human osteoblastic MG-63 cell cultures.
Effects of bisphosphonate on the release of MMP-2 from cultured human osteoblasts.
Effects of tetracyclines on bone metabolism.
EGF and IL-1 alpha modulate the release of collagenase, gelatinase and TIMP-1 as well as the release of calcium by rabbit calvarial bone explants.
ETV5 as a regulator of matrix metalloproteinase 2 in human chondrosarcoma.
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis.
Expression of MMP-2, 9 and 13 in newly formed bone after sinus augmentation using inorganic bovine bone in human.
Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout mice.
Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase.
Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines.
Interleukin-1 and tumor necrosis factor-alpha induce collagenolysis and bone resorption by regulation of matrix metalloproteinase-2 in mouse calvarial bone cells.
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption.
Matrix metalloproteinase inhibition attenuates aortic calcification.
Matrix metalloproteinases and metastatic cancer.
Matrix metalloproteinases in periodontal tissue remodelling.
Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MMI270 (CGS27023A), in patients with advanced solid cancer.
Potential anti-arthritic and anti-inflammatory effects of TNF-? processing inhibitor-1 (TAPI-1): A new approach to the treatment of S. aureus arthritis.
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
Role of Chemically Modified Tetracyclines in the Management of Periodontal Diseases: A Review.
Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis.
Soluble IL-6R alpha upregulated IL-6, MMP-1 and MMP-2 secretion in bone marrow stromal cells.
Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts.
The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells.
The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts.
The virulence factor GroEL promotes gelatinase secretion from cells in the osteoblast lineage: Implication for direct crosstalk between bacteria and adult cells.
Timp-1, -2 and -3 show coexpression with gelatinases A and B during mouse tooth morphogenesis.
Wnt signaling pathway inhibitors as promising diagnostic serum markers of osteolytic bone metastasis.
Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment.
Bowen's Disease
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Brain Contusion
Brain contusions induce a strong local overexpression of MMP-9. Results of a pilot study.
Brain Diseases
HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy.
Brain Edema
2-Chloroethanol Induced Upregulation of Matrix Metalloproteinase-2 in Primary Cultured Rat Astrocytes Via MAPK Signal Pathways.
Chlorogenic acid ameliorates brain damage and edema by inhibiting matrix metalloproteinase-2 and 9 in a rat model of focal cerebral ischemia.
Effect of Propofol Post-treatment on Blood-Brain Barrier Integrity and Cerebral Edema After Transient Cerebral Ischemia in Rats.
Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases and maintaining blood-brain barrier integrity in mice.
HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats.
Matrix metalloproteinase inhibition attenuates brain edema after surgical brain injury.
MATRIX METALLOPROTEINASE INHIBITION ATTENUATES BRAIN EDEMA IN AN IN VIVO MODEL OF SURGICALLY-INDUCED BRAIN INJURY.
Matrix metalloproteinase inhibition attenuates brain edema in an in vivo model of surgically-induced brain injury.
MATRIX METALLOPROTEINASE INHIBITION ATTENUATES BRAIN EDEMA IN AN IN VIVO MODEL OF SURGICALLY-INDUCED BRAIN INJURY.
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Proteolytic cascade enzymes increase in focal cerebral ischemia in rat.
Reduced brain edema and matrix metalloproteinase (MMP) expression by pre-reperfusion infusion into ischemic territory in rat.
SIRT1 inhibition by sirtinol aggravates brain edema after experimental subarachnoid hemorrhage.
[Study on expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in brain tissue adjacent to hemorrhage after brain hemorrhage in human]
Brain Infarction
Effects of tissue plasminogen activator on cerebral microvessels of rats during focal cerebral ischemia and reperfusion.
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Brain Injuries
Carnosine Attenuates Brain Oxidative Stress and Apoptosis After Intracerebral Hemorrhage in Rats.
Delayed administration of a matrix metalloproteinase inhibitor limits progressive brain injury after hypoxia-ischemia in the neonatal rat.
Examination of Gelatinase Isoforms in Rodent Models of Acute Neurodegenerative Diseases Using Two-Dimensional Zymography.
Heterogeneity of serum gelatinases MMP-2 and MMP-9 isoforms and charge variants.
Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia.
Matrix metalloproteinase inhibitor KB-R7785 attenuates brain damage resulting from permanent focal cerebral ischemia in mice.
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Molecular pathology of pulmonary edema after injury in forensic autopsy cases.
Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage.
Proteolytic processed form of CXCL12 abolishes migration and induces apoptosis in neural stem cells in vitro.
Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window.
Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries.
Brain Injuries, Traumatic
CXCL12/CXCR4 Axis Improves Migration of Neuroblasts Along Corpus Callosum by Stimulating MMP-2 Secretion After Traumatic Brain Injury in Rats.
Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse.
Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1alpha expression.
The role of matrix metalloproteinases in infant traumatic brain injury.
Brain Ischemia
?2-Adrenergic Receptor-Mediated HIF-1? Upregulation Mediates Blood Brain Barrier Damage in Acute Cerebral Ischemia.
A non-steroidal anti-inflammatory agent provides significant protection during focal ischemic stroke with decreased expression of matrix metalloproteinases.
Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia.
Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia.
Chlorogenic acid ameliorates brain damage and edema by inhibiting matrix metalloproteinase-2 and 9 in a rat model of focal cerebral ischemia.
Crocin protects against cerebral- ischemia-induced damage in aged rats through maintaining the integrity of blood-brain barrier.
Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice.
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
Expression and activation of matrix metalloproteinase-2 and -9 in rat brain after transient focal cerebral ischemia.
Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke.
Green tea polyphenol (-)-epigallocatechin gallate reduces matrix metalloproteinase-9 activity following transient focal cerebral ischemia.
Green tea polyphenol (-)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia.
Inhibition of HIF-1? Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia.
Inhibition of matrix metalloproteinase-2 and 9 by Piroxicam confer neuroprotection in cerebral ischemia: an in silico evaluation of the hypothesis.
Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.
Matrix metalloproteinase expression after human cardioembolic stroke: temporal profile and relation to neurological impairment.
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Matrix metalloproteinases increase very early during experimental focal cerebral ischemia.
Melatonin decreases matrix metalloproteinase-9 activation and expression and attenuates reperfusion-induced hemorrhage following transient focal cerebral ischemia in rats.
Mito-Tempo prevents nicotine-induced exacerbation of ischemic brain damage.
Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia.
Reduction of hemorrhagic transformation by PJ34, a poly(ADP-ribose)polymerase inhibitor, after permanent focal cerebral ischemia in mice.
Resveratrol inhibits matrix metalloproteinases to attenuate neuronal damage in cerebral ischemia: a molecular docking study exploring possible neuroprotection.
Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.
Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation.
The significance of matrix metalloproteinase (MMP)-2 and MMP-9 in the ischemic stroke.
Up-regulation of brain cytokines and metalloproteinases 1 and 2 contributes to neurological deficit and brain damage in transient ischemic stroke.
Brain Neoplasms
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice.
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Chapter 4 - Applications of nanotechnology in molecular imaging of the brain.
Development of a gene/drug dual delivery system for brain tumor therapy: potent inhibition via RNA interference and synergistic effects.
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion.
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors.
Inhibition of MMP-2 secretion from brain tumor cells suggests chemopreventive properties of a furanocoumarin glycoside and of chalcones isolated from the twigs of Dorstenia turbinata.
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Matrix metalloproteinase 2 attenuates brain tumour growth, while promoting macrophage recruitment and vascular repair.
Matrix metalloproteinase inhibition by green tea catechins.
Possible pathophysiological role of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in metastatic brain tumor-associated intracerebral hemorrhage.
Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors.
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Targeted delivery of silver nanoparticles and alisertib: in vitro and in vivo synergistic effect against glioblastoma.
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Urinary biomarkers predict brain tumor presence and response to therapy.
Breast Diseases
Gelatinase-a/mmp-2 serum levels and neoplastic progression in breast-cancer patients.
Plasma concentration and activity of matrix metalloproteinase 2 and 9 in patients with breast disease, breast cancer and at risk of developing breast cancer.
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Breast Neoplasms
53BP1 is a novel regulator of angiogenesis in breast cancer.
72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization.
A fluorescence nanoprobe for detecting the effect of different oxygen and nutrient conditions on breast cancer cells' migration and invasion.
A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.
A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1.
A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier.
A single ets-related transcription factor, E1AF, confers invasive phenotype on human cancer cells.
A stimuli-responsive Janus peptide dendron-drug conjugate as a safe and nanoscale drug delivery vehicle for breast cancer therapy.
Acquisition of new tumor cell properties by MSC-derived exosomes.
Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells.
Activated Leukocyte Cell Adhesion Molecule (ALCAM) is associated with suppression of breast cancer cells invasion.
Activation of kinin B1 receptor increases the release of metalloproteases-2 and -9 from both estrogen-sensitive and -insensitive breast cancer cells.
Activation of matrix metalloproteinase-2 and -9 by 2- and 4-hydroxyestradiol.
Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species.
Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2.
Activator Protein-2? Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
Activity of MMP-2 and MMP-9 in sera of breast cancer patients.
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression.
An aqueous extract from toad skin prevents gelatinase activities derived from fetal serum albumin and serum-free culture medium of human breast carcinoma MDA-MB-231 cells.
An Au-Se nanoprobe for the evaluation of the invasive potential of breast cancer cells via imaging the sequential activation of uPA and MMP-2.
Analysis of the MMP-dependent and independent functions of tissue inhibitor of metalloproteinase-2 on the invasiveness of breast cancer cells.
Anti-cancer effect of metformin on the metastasis and invasion of primary breast cancer cells through mediating NF-kB activity.
Anti-cancer effects of Piper nigrum via inducing multiple molecular signaling in vivo and in vitro.
Apatinib Inhibits Stem Properties and Malignant Biological Behaviors of Breast Cancer Stem Cells by Blocking Wnt/?-catenin Signal Pathway Through Down-regulating LncRNA ROR.
Apoptotic Induction and Anti-Migratory Effects of Rhazya Stricta Fruit Extracts on a Human Breast Cancer Cell Line.
Association between Expression of Tissue Inhibitors of Metalloproteinases-1, Matrix Metalloproteinase-2, and Matrix Metalloproteinase-9 Genes and Axillary Lymph Nodes Metastasis in Patients with Breast Cancer.
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer.
Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.
Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression.
Augmented release of matrix metalloproteinase-9 by PKC activation in organotypic cultures of human breast cancer and adjacent normal breast tissue and fibroadenoma.
Biomarkers of anticancer activity of R115777 (Tipifarnib, Zarnestra) in human breast cancer models in vitro.
Blockade of Asparagine Endopeptidase Inhibits Cancer Metastasis.
Body fluid MMP-2 as a putative biomarker in metastatic breast cancer.
Bone-Seeking Matrix Metalloproteinase-2 Inhibitors Prevent Bone Metastatic Breast Cancer Growth.
Breast cancer cell invasion mediated by G?12 signaling involves expression of interleukins-6 and -8, and matrix metalloproteinase-2.
Brucine suppresses breast cancer metastasis via inhibiting epithelial mesenchymal transition and matrix metalloproteinases expressions.
C-terminal binding protein-2 promotes cell proliferation and migration in breast cancer via suppression of p16INK4A.
Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-?1.
Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.
Cell surface immunophenotype and gelatinase activity of the human breast carcinoma cell line (MCF-7/6) with functionally defective E-cadherin.
Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. Monoclonal antibody production, isolation, and localization.
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue.
Clinical role of MiRNA 29a and MiRNA 335 on breast cancer management: their relevance to MMP2 protein level.
Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.
Clinical significance of plasma MMP-2 and MMP-9 levels as biomarkers for tumor expression in breast cancer patients in Egypt.
Clinical Study of Tumor Angiogenesis and Perfusion Imaging Using Multi-slice Spiral Computed Tomography for Breast Cancer.
Clodronate treatment influences MMP-2 associated outcome in node positive breast cancer.
Cobalt chloride-induced hypoxia modulates the invasive potential and matrix metalloproteinases of primary and metastatic breast cancer cells.
Collagen induced MMP-2 activation in human breast cancer.
Common matrix metalloproteinase-2 gene variants and altered susceptibility to breast cancer and associated features in Tunisian women.
Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells.
Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94).
Correlation between bone scan findings and collagenase activities in patients with breast cancer.
Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential.
Correlation of tissue inhibitor of metalloproteinase-2 with proliferative activity and patients' survival in breast cancer.
Curcumin effect on MMPs and TIMPs genes in a breast cancer cell line.
Current evidence on the relationship between four polymorphisms in the matrix metalloproteinases (MMP) gene and breast cancer risk: a meta-analysis.
Daidzein, R-(+)equol and S-(-)equol inhibit the invasion of MDA-MB-231 breast cancer cells potentially via the down-regulation of matrix metalloproteinase-2.
Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells.
Different expression patterns of MMP-2 and MMP-9 in breast cancer.
Differential regulation of matrix metalloproteinase-2 activation in human breast cancer cell lines.
Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2.
Doxorubicin conjugated with a trastuzumab epitope and an MMP-2 sensitive peptide linker for the treatment of HER2-positive breast cancer.
Effect of bevacizumab combined with docetaxel in the treatment of HER-2-negative recurrent metastatic breast cancer.
Effect of methanolic and water extract of Leucobryum bowringii Mitt. on growth, migration and invasion of MCF 7 human breast cancer cells in vitro.
Effect of microRNA-206 on cytoskeleton remodelling by downregulating Cdc42 in MDA-MB-231 cells.
Effect of MMP-2 gene silencing on radiation-induced DNA damage in human normal dermal fibroblasts and breast cancer cells.
Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines.
Effect of Sirtuin 1 inhibition on matrix metalloproteinase 2 and Forkhead box O3a expression in breast cancer cells.
Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells.
Effects of Lidocaine and Src Inhibition on Metastasis in a Murine Model of Breast Cancer Surgery.
Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the invasive capacity of these cell lines in vitro.
Effects of specific DNMT-gene depletion on cancer cell transformation and breast cancer cell invasion; towards selective DNMT inhibitors.
Eicosanoids as mediators of linoleic acid-stimulated invasion and type IV collagenase production by a metastatic human breast cancer cell line.
Electrophoretic analysis of proteins associated with tumor cell invasion.
Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells.
Elevated expression of both MDR1 and MMP-2 genes in metastasized lymph node of invasive ductal breast cancer.
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.
Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence.
Enhancing effect of platelet-derived microvesicles on the invasive potential of breast cancer cells.
Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells.
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Epigenetic induction of tissue inhibitor of matrix metalloproteinase-3 by green tea polyphenols in breast cancer cells.
Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts.
Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-?B signaling.
Evaluation of Matrix Metalloproteinase-2 (MMP-2) Activity with Film in situ Zymography for Improved Cytological Diagnosis of Breast Tumors.
Evaluation of potential Stat3-regulated genes in human breast cancer.
Ex-FABP: a fatty acid binding lipocalin developmentally regulated in chicken endochondral bone formation and myogenesis.
Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model.
Expression and correlation of Twist and gelatinases in breast cancer.
Expression of activated gelatinase in human invasive breast carcinoma.
Expression of Alpha-Enolase (ENO1), Myc Promoter-Binding Protein-1 (MBP-1) and Matrix Metalloproteinases (MMP-2 and MMP-9) Reflect the Nature and Aggressiveness of Breast Tumors.
Expression of E-cadherin, beta-catenin, cathepsin D, gelatinases and their inhibitors in invasive ductal breast carcinomas.
Expression of gelatinases A and B, stromelysin-3 and matrilysin genes in breast carcinomas: clinico-pathological correlations.
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.
Expression of matrix metalloproteinase 2 and 9 in breast cancer and breast fibroadenoma: a randomized, double-blind study.
Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells.
Expression of metalloproteinases MMP-2 and MMP-9 in sentinel lymph node and serum of patients with metastatic and non-metastatic breast cancer.
Expression of MiR-335 and its target metalloproteinase genes: clinical significance in breast cancer.
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Expression of MMP2, MMP9 and MMP3 in breast cancer brain metastasis in a rat model.
Expression of mRNA for gelatinase A and TIMP-2 in cell cultures and tissue samples derived from breast and lung carcinomas.
Expression of neurotensin and NT1 receptor in human breast cancer: a potential role in tumor progression.
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Expression of PEA3/E1AF/ETV4, an Ets-related transcription factor, in breast tumors: positive links to MMP2, NRG1 and CGB expression.
Expression of proteinases and inhibitors in human breast cancer progression and survival.
Expression of tissue inhibitor of metalloproteinase-1 and type IV collagenase/gelatinase messenger RNAs in human breast cancer.
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast.
Extracellular heat shock protein (Hsp)70 and Hsp90? assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion.
Ezrin-Radixin-Moesin Binding Phosphoprotein 50 (EBP50) Suppresses the Metastasis of Breast Cancer and HeLa Cells by Inhibiting Matrix Metalloproteinase-2 Activity.
Fibronectin affects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines.
Formononetin Inhibits Migration and Invasion of MDA-MB-231 and 4T1 Breast Cancer Cells by Suppressing MMP-2 and MMP-9 Through PI3K/AKT Signaling Pathways.
Fucosyltransferase 8 deficiency suppresses breast cancer cell migration by interference of the FAK/integrin pathway.
Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9.
GALNT14 mediates tumor invasion and migration in breast cancer cell MCF-7.
Gelatin zymography and substrate cleavage assays of matrix metalloproteinase-2 in breast carcinoma cells overexpressing membrane type-1 matrix metalloproteinase.
Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy.
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Gelatinase concentrations and zymographic profiles in human breast cancer: matrix metalloproteinases circulating in plasma are better markers for the subclassification and early prediction of cancer: the coagulation/fibrinolysis pathways alter the release, activation and recovery of different gelatinases in serum.
Gelatinase levels in male and female breast cancer.
Gelatinase-a/mmp-2 serum levels and neoplastic progression in breast-cancer patients.
Gene Polymorphisms and Circulating Levels of MMP-2 and MMP-9: A Review of Their Role in Breast Cancer Risk.
Genetic polymorphisms in the MMP-2 and MMP-9 genes and breast cancer phenotype.
Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.
Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors.
HIF-2? as a prognostic marker for breast cancer progression and patient survival.
How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study.
Human brain endothelial cell-derived COX-2 facilitates extravasation of breast cancer cells across the blood-brain barrier.
Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation.
Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells.
Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages.
Identification of the functional role of AF1Q in the progression of breast cancer.
Immunolocalization of matrix metallo-proteinases and their tissue inhibitor in human mammary pathology.
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Implication of alpha5beta1 integrin in invasion of drug-resistant MCF-7/ADR breast carcinoma cells: a role for MMP-2 collagenase.
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
In vitro and in vivo antitumorigenic activity of a mixture of lysine, proline, ascorbic acid, and green tea extract on human breast cancer lines MDA-MB-231 and MCF-7.
Increase in tissue inhibitor of metalloproteinase-2 (TIMP-2) levels and inhibition of MMP-2 activity in a metastatic breast cancer cell line by an anti-invasive small molecule SR13179.
Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer.
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Increased invasive potential and up-regulation of MMP-2 in MDA-MB-231 breast cancer cells expressing the beta3 integrin subunit.
Indole-3-carbinol inhibits Sp1-induced matrix metalloproteinase-2 expression to attenuate migration and invasion of breast cancer cells.
Induction of matrix metalloproteinases MMP-1 and MMP-2 by co-culture of breast cancer cells and bone marrow fibroblasts.
Inhibition of breast cancer cell extracellular matrix degradative activity by chemically modified tetracyclines.
Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor.
Inhibition of Metastatic Tumor Growth and Metastasis via Targeting Metastatic Breast Cancer by Chlorotoxin-Modified Liposomes.
Inhibition of MT1-MMP proteolytic function and ERK1/2 signalling influences cell migration and invasion through changes in MMP-2 and MMP-9 levels.
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo.
Integrin alpha5beta1 controls invasion of human breast carcinoma cells by direct and indirect modulation of MMP-2 collagenase activity.
Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
Interaction between CD147 and P-glycoprotein and their regulation by ubiquitination in breast cancer cells.
Invasiveness of breast cancer cells MDA-MB-231 through extracellular matrix is increased by the estradiol metabolite 4-hydroxyestradiol.
Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis.
Irradiation of normal mouse tissue increases the invasiveness of mammary cancer cells.
Knockdown of hypoxia inducible factor-2? inhibits cell invasion via the downregulation of MMP-2 expression in breast cancer cells.
Lack of association between the matrix metalloproteinase-2 -1306C>T polymorphism and breast cancer susceptibility: a meta-analysis.
LASS2/TMSG1 inhibits growth and invasion of breast cancer cell in vitro through regulation of vacuolar ATPase activity.
Leptin utilizes Jun N-terminal kinases to stimulate the invasion of MCF-7 breast cancer cells.
Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography.
Localization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells.
Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response?
Low serum level of pro-matrix metalloproteinase 2 correlates with aggressive behavior in breast carcinoma.
Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.
Lycorine inhibits the growth and metastasis of breast cancer through the blockage of STAT3 signaling pathway.
M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer.
Mast cell tryptase promotes breast cancer migration and invasion.
Matrix metalloproteinase-2 (MMP-2) in T(1-2)N0 breast carcinoma.
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma.
Matrix metalloproteinase-2 (MMP-2) is associated with the risk for a relapse in postmenopausal patients with node-positive breast carcinoma treated with antiestrogen adjuvant therapy.
Matrix metalloproteinase-2 C(-1306)T promoter polymorphism and breast cancer risk in the Saudi population.
Matrix metalloproteinase-2 immunoreactive protein: a marker of aggressiveness in breast carcinoma.
Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review.
Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.
Matrix Metalloproteinase-2 Promoter Polymorphism Is Associated with Breast Cancer in a Mexican Population.
Matrix metalloproteinase-2: A key regulator in coagulation proteases mediated human breast cancer progression through autocrine signaling.
Matrix Metalloproteinase-9 -1562T Allele and its Combination with MMP-2 -735 C Allele are Risk Factors for Breast Cancer.
Matrix metalloproteinases and metastatic cancer.
Matrix metalloproteinases in neoplasm-induced extracellular matrix remodeling in breast carcinomas.
MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Meta-analysis on the relationship between the SNP of MMP-2-1306 C>T and susceptibility to breast cancer.
Metalloproteinases 1 and 3 as Potential Biomarkers in Breast Cancer Development.
MMP-2 -1306C>T polymorphism in breast cancer: a case-control study in a South European population.
MMP-2 and MMP-9 activity is regulated by estradiol and tamoxifen in cultured human breast cancer cells.
MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions.
MMP-2 positivity and age less than 40 years increases the risk for recurrence in premenopausal patients with node-positive breast carcinoma.
MMP-2 protein in invasive breast cancer and the impact of MMP-2/TIMP-2 phenotype on overall survival.
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
MMP-2, MMP-9, VEGF and CA 15.3 in breast cancer.
MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: correlations with prognostic factors.
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits.
MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2.
Momordica cochinchinensis Seed Extracts Suppress Migration and Invasion of Human Breast Cancer ZR-75-30 Cells Via Down-regulating MMP-2 and MMP-9.
Monensin inhibits proliferation, migration, and promotes apoptosis of breast cancer cells via downregulating UBA2.
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells.
Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7.
Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.
Neurokinin-1 receptor mediated breast cancer cell migration by increased expression of MMP-2 and MMP-14.
New Insights into the Occurrence of Matrix Metalloproteases -2 and -9 in a Cohort of Breast Cancer Patients and Proteomic Correlations.
New pathway links from cancer-progression determinants to gene expression of matrix metalloproteinases in breast cancer cells.
Novel ternary vanadium-betaine-peroxido species suppresses H-ras and matrix metalloproteinase-2 expression by increasing reactive oxygen species-mediated apoptosis in cancer cells.
NRF3 suppresses breast cancer cell metastasis and cell proliferation and is a favorable predictor of survival in breast cancer.
Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases.
Oncological Risk in Autologous Stem Cell Donation for Novel Tissue-Engineering Approaches to Postmastectomy Breast Regeneration.
Overexpression of MMP Family Members Functions as Prognostic Biomarker for Breast Cancer Patients: A Systematic Review and Meta-Analysis.
Papers to appear in forthcoming issues
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Pattern of collagen fibers and localization of matrix metalloproteinase 2 and 9 during breast cancer invasion.
Phosphocitrate inhibits calcium hydroxyapatite induced mitogenesis and upregulation of matrix metalloproteinase-1, interleukin-1beta and cyclooxygenase-2 mRNA in human breast cancer cell lines.
Photothermal/matrix metalloproteinase-2 dual-responsive gelatin nanoparticles for breast cancer treatment.
Physical exercise modulates the level of serum MMP-2 and MMP-9 in patients with breast cancer.
Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Plasma concentration and activity of matrix metalloproteinase 2 and 9 in patients with breast disease, breast cancer and at risk of developing breast cancer.
Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables.
Plasma Levels and Diagnostic Utility of M-CSF, MMP-2 and its Inhibitor TIMP-2 in the Diagnostics of Breast Cancer Patients.
Plasma levels and diagnostic utility of VEGF, MMP-2 and TIMP-2 in the diagnostics of breast cancer patients.
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Plasma matrix metalloproteinase 2 levels and breast cancer risk.
Platelet derived growth factor increases phospholipase D1 but not phospholipase D2 expression via NFkappaB signaling pathway and enhances invasion of breast cancer cells.
Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects.
Polyphenols from Artemisia annua L Inhibit Adhesion and EMT of Highly Metastatic Breast Cancer Cells MDA-MB-231.
Polysaccharide from
Potential of fluorescent metalloproteinase substrates for cancer detection.
Preoperative Serum Levels of Matrix Metalloproteinase-2 (MMP-2) and Survival of Breast Cancer among Korean Women.
Prevalence of vascular-endothelial growth factor, matrix metalloproteinases and tissue inhibitors of metalloproteinases in primary breast cancer.
Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice.
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloproteinase tissue inhibitor-2 promoters in breast cancer in Tunisia: case-control study.
Prognostic significance of stromelysin 3, gelatinase A, and urokinase expression in breast cancer.
Prognostic value of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9) and aminopeptidase N/CD13 in breast cancer patients.
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Prognostic values of ETS-1, MMP-2 and MMP-9 expression and co-expression in breast cancer patients.
Propoxur enhances MMP-2 expression and the corresponding invasion of human breast cancer cells via the ERK/Nrf2 signaling pathway.
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion.
Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells.
Quantitatively Visualizing Tumor-Related Protease Activity in Vivo Using a Ratiometric Photoacoustic Probe.
Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium.
Realgar Nanoparticles Inhibit Migration, Invasion and Metastasis in a Mouse Model of Breast Cancer by Suppressing Matrix Metalloproteinases and Angiogenesis.
Reciprocal effects of ascorbate on cancer cell growth and the expression of matrix metalloproteinases and transforming growth factor-beta.
Reduced expression of Snail decreases breast cancer cell motility by downregulating the expression and inhibiting the activity of RhoA GTPase.
Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.
Relationship between matrix metalloproteinase expression and tumor angiogenesis in human breast carcinoma.
Relationships Between Immunophenotype, Ki-67 Index, Microvascular Density, Ep-CAM/P-cadherin, and MMP-2 Expression in Early-stage Invasive Ductal Breast Cancer.
Relationships between the level of matrix metalloproteinase-2 and tumor size of breast cancer.
Requirements for estrogen receptor alpha membrane localization and function.
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
Resveratrol inhibits migration and invasion of human breast-cancer cells.
Role of DDR1 in the gelatinases secretion induced by native type IV collagen in MDA-MB-231 breast cancer cells.
Role of matrix metalloproteinase-2 in ethanol-induced invasion by breast cancer cells.
Role of PTHrp and PTHrp-engaged pathways in MCF-7 cells migration/invasion.
Role of serum matrix metalloproteinase-2 and -9 to predict breast cancer progression.
S-Allylcysteine reduces breast tumor cell adhesion and invasion.
Salinomycin suppresses TGF-?1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells.
Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways.
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Serum and tissue expression of gelatinase and Twist in breast cancer.
Serum levels of matrix metalloproteinase 2 in patients with breast cancer.
Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients.
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their tissue natural inhibitors in breast tumors.
Silencing of KIF3B Suppresses Breast Cancer Progression by Regulating EMT and Wnt/?-Catenin Signaling.
Silencing of TMSG1 enhances metastasis capacity by targeting V-ATPase in breast cancer.
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma.
SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines.
Stimulation of type IV collagenase expression by linoleic acid in a metastatic human breast cancer cell line.
Stromal expression of matrix metalloproteinase 2 in cancer-associated fibroblasts is strongly related to human epidermal growth factor receptor 2 status in invasive breast carcinoma.
Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.
Stromelysin-3 mRNA expression and malignancy: comparison with clinicopathological features and type IV collagenase mRNA expression in breast tumors.
Studies on Multifunctional Effect of All-Trans Retinoic Acid (ATRA) on Matrix Metalloproteinase-2 (MMP-2) and Its Regulatory Molecules in Human Breast Cancer Cells (MCF-7).
Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes.
Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling.
Super Magnetic Niosomal Nanocarrier as a New Approach for Treatment of Breast Cancer: A Case Study on SK-BR-3 and MDA-MB-231 Cell Lines.
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action.
Suppression of type IV collagenase in MDA-MB-435 human breast cancer cells by eicosapentaenoic acid in vitro and in vivo.
Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions.
Synthesis, characterization and in vitro study of biocompatible cinnamaldehyde functionalized magnetite nanoparticles (CPGF Nps) for hyperthermia and drug delivery applications in breast cancer.
Testin is a tumor suppressor and prognostic marker in breast cancer.
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.
The Anti-tumoral Effect of ?-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGF?1 Gene Expression in Pre-surgical Breast Cancer Patients.
The Difference of Expression of 18 Genes in Axillary Invasion and Vascular Invasion Compared to Control Samples in Breast Cancer.
The Effect of Chrysin Loaded PLGA-PEG on Metalloproteinase Gene Expression in Mouse 4T1 Tumor Model.
The Effects of Houttuynia cordata Thunb and Piper ribesioides Wall Extracts on Breast Carcinoma Cell Proliferation, Migration, Invasion and Apoptosis.
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway.
The G(12) family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion.
The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis.
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
The influence of opioids on matrix metalloproteinase-2 and -9 secretion and mRNA levels in MCF-7 breast cancer cell line.
The level of serum pro-matrix metalloproteinase-2 as a prognostic factor in patients with invasive ductal breast cancer.
The MMP-2 -735 C allele is a risk factor for susceptibility to breast cancer.
The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
The TGF-beta/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system.
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.
Tissue distribution of major matrix metalloproteinases and their transcripts in human breast carcinomas.
Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells.
TPX2 promotes migration and invasion of human breast cancer cells.
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Tumor cell specific expression of MMP-2 correlates with tumor vascularisation in breast cancer.
Tumor grade and matrix metalloproteinase 2 expression in stromal fibroblasts help to stratify the high-risk group of patients with early breast cancer identified on the basis of st gallen recommendations.
Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer.
Tumour-associated fibrinolysis: the prognostic relevance of plasminogen activators uPA and tPA in human breast cancer.
Type IV collagenase immunoreactivity in invasive breast carcinoma.
Tyrosine phosphorylation mediates ConA-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in MDA-MB-231 human breast carcinoma cells.
Unifloral ajwain honey ameliorates differential inhibition of matrix metalloproteinases 2 and 9 protein, cytotoxicity, and antioxidant potential.
Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells.
Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.
Values of MMP-2 and MMP-9 in Tumor Tissue of Basal-Like Breast Cancer Patients.
Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: potential anti-tumor effect in cancer invasion and metastasis.
Vitamin D, tamoxifen and beta-estradiol modulate breast cancer cell growth and interleukin-6 and metalloproteinase-2 production in three-dimensional co-cultures of tumor cell spheroids with endothelium.
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors.
Zymographic detection and clinical correlations of MMP-2 and MMP-9 in breast cancer sera.
[6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells.
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
[Clinical significance and relationship of expression of matrix metalloproteinase-2 mRNA with breast cancer metastasis.]
[Effect of ethyl gallate on invasion abilities and its mechanism of breast cancer MDA-MB-231 cells].
[Effect of lupeol on migration and invasion of human breast cancer MDA-MB-231 cells and its mechanism].
[Effects of Se-methylselenocysteine on Biological Behavior of and Matrix Metalloproteinase-2 Expression in Human Breast Cancer MDA-MB-231 Cells.]
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
[Expression of CD147, matrix metalloproteinases and transforming growth factor beta1 in breast cancer]
[Expression of matrix metalloproteinase (MMP-2) and extracellular matrix metalloproteinases inducer (EMMPRIN) in benign and advanced breast cancer tissue samples]
[Expression of TGF-beta1 and the mechanism of invasiveness and metastasis induced by TGF-beta1 in breast cancer]
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
[Inhibitory effect of luteolin on the angiogenesis of chick chorioallantoic membrane and invasion of breast cancer cells via downregulation of AEG-1 and MMP-2].
[Relationship between the expression of matrix metalloproteinase-13 protein and other biomarkers, prognosis in invasive breast cancer]
[Role of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factor C in lymph node metastasis of breast cancer.]
[Serum level of MMP-2 in early breast cancer and its correlation with circulating tumor cells].
[Stromal proteases in the progression of breast cancer]
[The expression of MMPs and TIMPs in human breast cancer tissues and importance of their balance in cancer invasion and metastasis]
[Zymography--method for quantitation of activity on gelatinase A (pro-MMP-2, 72 kDa) and gelatinase B (pro-MMP-9, 92 kDa) in serum of patients with breast cancer]
Bronchial Hyperreactivity
Tachykinins induce gelatinase production by guinea pig alveolar macrophages: involvement of NK2 receptors.
Bronchiectasis
Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis.
Matrix Metalloproteinases Vary with Airway Microbiota Composition and Lung Function in Non-Cystic Fibrosis Bronchiectasis.
Soluble membrane-type 1 matrix metalloproteinase (MT1-MMP) and gelatinase A (MMP-2) in induced sputum and bronchoalveolar lavage fluid of human bronchial asthma and bronchiectasis.
Bronchiolitis
Regression of Allograft Airway Fibrosis The Role of MMP-Dependent Tissue Remodeling in Obliterative Bronchiolitis after Lung Transplantation.
Bronchiolitis Obliterans
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome.
Bronchitis
Gelatinolytic and type IV collagenolytic activity in bronchiectasis.
Bronchopulmonary Dysplasia
Gelatinase activities in the airways of premature infants and development of bronchopulmonary dysplasia.
Low levels of tissue inhibitor of metalloproteinase-2 at birth may be associated with subsequent development of bronchopulmonary dysplasia in preterm infants.
MMP-2 and MMP-9 and their tissue inhibitors in the plasma of preterm and term neonates.
Bundle-Branch Block
Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.
Burkitt Lymphoma
PEG10 promotes the migration of human Burkitt's lymphoma cells by up-regulating the expression of matrix metalloproteinase-2 and -9.
Burning Mouth Syndrome
Effect of a Homemade Salivary Substitute Prepared Using Chamomile (Matricaria chamomilla L.) Flower and Flax (Linum usitatissimum L.) Seed to Relieve Primary Burning Mouth Syndrome: A Preliminary Report.
Campylobacter Infections
Colonic Expression of Genes Encoding Inflammatory Mediators and Gelatinases During Campylobacter Jejuni Infection of Conventional Infant Mice.
Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice.
Capsule Opacification
Induction of matrix metalloproteinases 2 and 9 following stress to the lens.
Carcinogenesis
A significant elevation of plasma level of matrix metalloproteinase-9 in patients with high-grade intraepithelial neoplasia and early squamous cell carcinoma of the uterine cervix.
A study on angiogenesis-related matrix metalloproteinase networks in primary hepatocellular carcinoma.
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Angiogenin contributes to bladder cancer tumorigenesis by DNMT3b-mediated MMP2 activation.
Annexin A3 Knockdown Suppresses Lung Adenocarcinoma.
Anticancer effects of tanshinone I in human non-small cell lung cancer.
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population.
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
CKAP2 Promotes Ovarian Cancer Proliferation and Tumorigenesis Through the FAK-ERK Pathway.
Cutaneous carcinomas and preinvasive neoplastic lesions. Role of MMP-2 and MMP-9 metalloproteinases in neoplastic invasion and their relationship with proliferative activity and p53 expression.
Deregulation of collagen metabolism in human stomach cancer.
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice.
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis.
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Expression of Matrix Metalloproteinase-2, but not Caspase-3, Facilitates Distinction between Benign and Malignant Thyroid Follicular Neoplasms.
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis.
Gelatinases A and B expression in human colorectal cancer in upper Egypt: a clinicopathological study.
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity.
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells.
Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis.
Matrix metalloproteinase inhibitors: do they have a place in anticancer therapy?
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
MMP-9 directed shRNAs as relevant inhibitors of matrix metalloproteinase 9 activity and signaling.
MMP2 and TLRs modulate immune responses in the tumor microenvironment.
Modulating Effect of Enicostemma littorale on the Expression Pattern of Apoptotic, Cell Proliferative, Inflammatory and Angiogenic Markers During 7, 12-Dimethylbenz (a) Anthracene Induced Hamster Buccal Pouch Carcinogenesis.
Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9.
Molecular biology of the nasal airways: how do we assess cellular and molecular responses in the nose?
Neutral endopeptidase 24.11/CD10 suppresses progressive potential in ovarian carcinoma in vitro and in vivo.
Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice.
Oncogenic roles of astrocyte elevated gene-1 (AEG-1) in osteosarcoma progression and prognosis.
Oncogenic transformation of human benign prostate hyperplasia with chronic cadmium exposure.
Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(?)anthracene-induced rat mammary carcinogenesis.
Overexpression of EMMPRIN Isoform 2 Is Associated with Head and Neck Cancer Metastasis.
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
POU5F1 enhances the invasiveness of cancer stem-like cells in lung adenocarcinoma by upregulation of MMP-2 expression.
Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-?B Pathway.
Rho Guanine Nucleotide Exchange Factor 5 Increases Lung Cancer Cell Tumorigenesis via MMP-2 and Cyclin D1 Upregulation.
Role of fibrillar Tenascin-C in metastatic pancreatic cancer.
Role of the TNF-? receptor type 1 on prostate carcinogenesis in knockout mice.
Semi-quantitative expression of tissue inhibitor of matrix metalloproteinase-2 in cancer of uterine cervix.
Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis.
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases.
The Anti-tumoral Effect of ?-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGF?1 Gene Expression in Pre-surgical Breast Cancer Patients.
The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-alpha in human keratinocytes.
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
TIMP-2 G-418C polymorphism and cancer risk: A meta-analysis.
Transcriptional expression of the genes implicated in angiogenesis and tumor invasion in cervical carcinomas.
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression.
Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence.
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
[Expression of MMP-2, HIF-1alpha and VEGF in Colon Adenoma and Colon Cancer.]
[FABP5 promotes cell growth, invasion and metastasis in cervical cancer].
[Gelatinases A and B and their endogenous regulators in the corpus uteri in squamous cell cervical carcinoma].
[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1]
[State of the liver antioxidant system and content of matrix metalloproteinase-2 of the large intestine under the effect of maleimide derivative in experimental colorectal carcinogenesis in rats].
[The matrix metalloproteinase in oral and oropharyngeol cancer - literature review].
[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus]
Carcinoid Tumor
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
GHRH antagonist inhibits focal adhesion kinase (FAK) and decreases expression of vascular endothelial growth factor (VEGF) in human lung cancer cells in vitro.
Carcinoma
72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization.
72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells.
92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma.
A comparative study of MMP-2 in vulvar neoplasms.
A matrix metalloproteinase expressed on the surface of invasive tumour cells.
A multicenter study on expressions of vascular endothelial growth factor, matrix metallopeptidase-9 and tissue inhibitor of metalloproteinase-2 in oral and maxillofacial squamous cell carcinoma.
A role for focal adhesion kinase in hyluronan-dependent MMP-2 secretion in a human small-cell lung carcinoma cell line, QG90.
Aberrant activation of Wnt/?-catenin signaling pathway contributes to the sequential progression of DMBA-induced HBP carcinomas.
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.
Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: possible regulation of pro-MMP-2 activation by TIMP-2.
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Activation of Toll-Like Receptor-9 Promotes Cellular Migration via Up-Regulating MMP-2 Expression in Oral Squamous Cell Carcinoma.
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Activity and cellular origin of gelatinases in patients with colon and rectal carcinoma differential activity of matrix metalloproteinase-9.
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
ADAM17 is associated with EMMPRIN and predicts poor prognosis in patients with uterine cervical carcinoma.
Adenovirus-mediated ING4 expression suppresses lung carcinoma cell growth via induction of cell cycle alteration and apoptosis and inhibition of tumor invasion and angiogenesis.
AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner.
ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Alteration of MMP-2 and -14 expression by imatinib in HPV-positive and -negative squamous cell carcinoma.
Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma.
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Ameloblastic neoplasia spectrum: a cross-sectional study of MMPS expression and proliferative activity.
An entropy-based statistic for genomewide association studies.
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Angiogenic factors in laryngeal carcinomas: do they have prognostic relevance?
Anti-cancer Effect of 20(S)-Ginsenoside-Rh2 on Oral Squamous Cell Carcinoma Cells via the Decrease in ROS and Downregulation of MMP-2 and VEGF.
Anti-invasive effect of MMI-166, a new selective matrix metalloproteinase inhibitor, in cervical carcinoma cell lines.
Anti-proliferative and matrix metalloproteinase-2 inhibition of Longkong (Lansium domesticum) extracts on human mouth epidermal carcinoma.
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Antimetastatic potentials of salvianolic acid A on oral squamous cell carcinoma by targeting MMP-2 and the c-Raf/MEK/ERK pathway.
Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells.
Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma.
Associations of Promoter Methylations and mRNA Expressions of MMP-2, MMP-7 and MMP-9 with Primary Fallopian Tube Carcinoma.
Augmented membrane type 1 matrix metalloproteinase (MT1-MMP):MMP-2 messenger RNA ratio in gastric carcinomas with poor prognosis.
Aurora-A modulates MMP-2 expression via AKT/NF-?B pathway in esophageal squamous cell carcinoma cells.
Autocrine factor enhancing the secretion of M(r) 95,000 gelatinase (matrix metalloproteinase 9) in serum-free medium conditioned with murine metastatic colon carcinoma cells.
BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells.
Basement membrane collagen-degrading activity from a malignant tumor is inhibited by anthracycline antibiotics.
Behavior of the basement membrane during carcinoma cell invasion in chemically induced carcinomas of the skin.
Behaviour of basement membrane antigens in gastric and colorectal cancer. Immunohistochemical study.
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity.
Calprotectin and the Initiation and Progression of Head and Neck Cancer.
Cancer-Specific Survival Stratification Derived from Tumor Expression of Tissue Inhibitor of Metalloproteinase-2 in Non-Metastatic Renal Cell Carcinoma.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
CD147 and matrix metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma.
CD40L induces matrix-metalloproteinase-9 but not tissue inhibitor of metalloproteinases-1 in cervical carcinoma cells: imbalance between NF-kappaB and STAT3 activation.
Cellular protein and mRNA expression patterns of matrix metalloproteinases-2, -3 and -9 in human breast cancer: correlation with tumour growth.
Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
Chronic stress promotes oral cancer growth and angiogenesis with increased circulating catecholamine and glucocorticoid levels in a mouse model.
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression.
Clinical significance of serum MMP-2 and MMP-7 in patients with ovarian cancer.
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma.
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Comparative analysis of the expression of metalloproteases (MMP-2, MMP-9, MMP-11 and MMP-13) and the tissue inhibitor of metalloprotease 3 (TIMP-3) between previous negative biopsies and radical prostatectomies.
Comparative expression of matrix metalloproteinases in low-grade mucoepidermoid carcinoma and typical lung cancer.
Comparative study of MMP-2 (matrix metalloproteinase 2) immune expression in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma.
Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas.
Comparisons of efficacy and safety between docetaxel + cisplatin and paclitaxel + cisplatin and their effects on serum HE4, CA125 and ROMA indicators in patients with ovarian carcinoma.
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Contribution of the PI3K/MMPs/Ln-5?2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas.
Coordinated expression of integrin subunits, matrix metalloproteinases (MMP), angiogenic genes and Ets transcription factors in advanced-stage ovarian carcinoma: a possible activation pathway?
Correction: liang, j., et Al. Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and e-cadherin. Int. J. Mol. Sci. 2012, 13, 10594-10607.
Correlation and prognostic significance of MMP-2 and TFPI-2 differential expression in pancreatic carcinoma.
Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas.
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma.
Correspondence re: C. F. M. Sier et al., Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers. Clin. Cancer Res., 6: 2333-2340, 2000.
Corrigendum: HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Critical roles of Wnt5a-Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ?Np63?-mediated epithelial-mesenchymal transition.
Curcumin Inhibits Invasiveness and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Through Reducing Matrix Metalloproteinase 2, 9 and Modulating p53-E-Cadherin Pathway.
Cutaneous carcinomas and preinvasive neoplastic lesions. Role of MMP-2 and MMP-9 metalloproteinases in neoplastic invasion and their relationship with proliferative activity and p53 expression.
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Desmoplastic basal cell carcinomas possess unique basement membrane-degrading properties.
Desmoplastic response in scirrhous gastric carcinoma: imbalance between collagen synthesis and degradation.
Detection of differentially expressed gelatinase A in metastatic and non-metastatic subpopulations of tumor cells by target RNA arbitrarily primed polymerase chain reaction (TRAP-PCR).
Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung.
Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma.
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma.
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
DJ-1 is involved in the peritoneal metastasis of gastric cancer through activation of the Akt signaling pathway.
Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression.
Downregulation of G3BPs inhibits the growth, migration and invasion of human lung carcinoma H1299 cells by suppressing the Src/FAK-associated signaling pathway.
Downregulation of miR-21 regulates MMP-2 expression and suppress migration of Laryngeal squamous cell carcinoma.
Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.
Early acquisition of gelatinolytic activity in carcinogenesis of the uterine cervix.
Effect of DAPK1 gene on proliferation, migration, and invasion of carcinoma of pancreas BxPC-3 cell line.
Effect of divalent metal ions on collagenase from Clostridium histolyticum.
Effect of epithelial growth factor on matrix metalloproteinase-2 and E-cadherin/?-catenin expression in an in situ model of tumorigenesis.
Effect on the Expression of MMP-2, MT-MMP in Laryngeal Carcinoma Hep-2 Cell Line by Antisense Glucose Transporter-1.
Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression.
Effects of basic fibroblast factor (bFGF) on MMP-2, TIMP-2, and type-I collagen levels in human lung carcinoma fibroblasts.
Effects of cigarette smoke condensate on oral squamous cell carcinoma cells.
Effects of matrix metalloproteinase inhibitor doxycycline and CD147 antagonist peptide-9 on gallbladder carcinoma cell lines.
Effects of RNA silencing of matrix metalloproteinase-2 on the growth of esophageal carcinoma cells in vivo.
Effects of RNAi-mediated matrix metalloproteinase-2 gene silencing on the invasiveness and adhesion of esophageal carcinoma cells, KYSE150.
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.
Elevation of serum levels of matrix metalloproteinase-2 and -3 as new predictors of recurrence in patients with urothelial carcinoma.
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas.
Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers.
Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2.
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-beta1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions.
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Expression and activation of proteases in co-cultures.
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis.
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma.
Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance.
Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival.
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Expression of Gelatinases (MMP-2, MMP-9) and Gelatinase Activator (MMP-14) in Actinic Keratosis and in In Situ and Invasive Squamous Cell Carcinoma.
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Expression of laminin, collagen IV, fibronectin, and type IV collagenase in gastric carcinoma. An immunohistochemical study of 87 patients.
Expression of matrix metalloprotease-2 (MMP-2) and the activator membrane type 1 (MT1-MMP) in canine mammary carcinomas.
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.
Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck.
Expression of matrix metalloproteinase 2 (MMP-2), E-cadherin and Ki-67 in metastatic and non-metastatic canine mammary carcinomas.
Expression of matrix metalloproteinase 2 (MMP-2), membrane-type 1 MMP and tissue inhibitor of metalloproteinase 2 and activation of proMMP-2 in pancreatic duct adenocarcinomas in hamsters treated with N-nitrosobis(2-oxopropyl)amine.
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Expression of matrix metalloproteinase in the fluids of renal cystic lesions.
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential.
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Expression of matrix metalloproteinase-2 in preinvasive and invasive carcinoma of the uterine cervix.
Expression of matrix metalloproteinase-2 in renal cell carcinoma.
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis.
Expression of matrix metalloproteinases (MMP-2 and MMP-9) in recurrent respiratory papillomas and laryngeal carcinoma: clinical and morphological parallels.
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Expression of matrix metalloproteinases (MMPs-2, -7, -9, and -26) and tissue inhibitors of metalloproteinases (TIMPs-1 and -2) in pleomorphic adenomas and adenoid cystic carcinomas.
Expression of Matrix Metalloproteinases and Its Inhibitor in Gastric Adenocarcinoma.
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in head and neck squamous cell carcinoma.
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Expression of membrane type 1 matrix metalloproteinase (MMP-14) in epithelial ovarian cancer: high level expression in clear cell carcinoma.
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Expression of membrane-type matrix metalloproteinase in human gastric carcinomas.
Expression of membrane-type-1-matrix metalloproteinase and metalloproteinase-2 in nonsmall cell lung carcinomas.
Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma.
Expression of metalloproteinase-2, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in transitional cell carcinoma of upper urinary tract: correlation with tumor stage and survival.
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma.
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Expression of MMP-2, -9 and -13 in cell lines and fresh biopsies of squamous cell carcinomas of the upper aerodigestive tract.
Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance.
Expression of mRNA for gelatinase A and TIMP-2 in cell cultures and tissue samples derived from breast and lung carcinomas.
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Expression of RECK and matrix metalloproteinase-2 in ameloblastoma.
Expression of RECK and MMP-2 in salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis.
Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice.
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Expression of type IV collagen and matrix metalloproteinase-2 (type IV collagenase) in relation to nodal status in laryngeal cancer.
Expression of type IV collagen, metalloproteinase-2, metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in laryngeal squamous cell carcinomas.
Expression profile of epithelial-mesenchymal transition markers in non-muscle-invasive urothelial carcinoma of the bladder: correlation with intravesical recurrence following transurethral resection.
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Fasudil inhibits proliferation and migration of Hep-2 laryngeal carcinoma cells.
Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor.
Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis.
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Galloyl cyclic-imide derivative CH1104I inhibits tumor invasion through suppressing matrix metalloproteinase activity.
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Gelatinase A (MMP-2) and its mRNA detected in both neoplastic and stromal cells of tumors with different invasive and metastatic properties.
Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy.
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Gelatinases and metalloproteinase inhibitor secreted by murine colonic carcinoma cells with differing metastatic potential.
Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography.
Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas.
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
HIF-1? contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma.
Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence.
Histopathological analysis of angiogenic factors in renal cell carcinoma.
HPV16 oncoproteins induce MMPs/RECK-TIMP-2 imbalance in primary keratinocytes: possible implications in cervical carcinogenesis.
Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
Human neutrophil peptide-1 affects matrix metalloproteinase-2, -8 and -9 secretions of oral squamous cell carcinoma cell lines in vitro.
Human recombinant interferons-beta and -gamma decrease gelatinase production and invasion by human KG-2 renal-carcinoma cells.
Human tongue carcinoma growth is inhibited by selective antigelatinolytic peptides.
Hyaluronan-CD44s signaling regulates matrix metalloproteinase-2 secretion in a human lung carcinoma cell line QG90.
Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation.
Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma.
Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease.
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways.
Immunocytochemical detection of matrix metalloproteinase expression in prostate cancer.
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Immunoexpression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in the metastasis of squamous cell carcinoma of the human tongue.
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Immunohistochemical expression of MMP-2 and MMP-8 in oral squamous cell carcinoma.
Immunohistochemical markers of prolonged survival in small cell carcinoma of the lung. An immunohistochemical study.
Immunohistochemically detected high expression of matrix metalloproteinase-2 as predictor of poor prognosis in Duke's B colon cancer.
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
In situ detection of PCR-amplified metalloproteinase cDNAs, their inhibitors and human papillomavirus transcripts in cervical carcinoma cell lines.
In situ mRNA hybridization technique for analysis of metastasis-related genes in human colon carcinoma cells.
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
In vivo and in vitro antitumor effect of a unique nutrient mixture on lung cancer cell line A-549.
In vivo and in vitro invasiveness of human lung carcinoma cell lines.
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer.
Increased cell-substratum adhesion, and decreased gelatinase secretion and cell growth, induced by E-cadherin transfection of human colon carcinoma cells.
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Increased expression of tissue inhibitor of metalloproteinase-2 in clear cell carcinoma of the ovary.
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Increased matrix metalloproteinase-2 expression and reduced tissue factor pathway inhibitor-2 expression correlate with angiogenesis and early postoperative recurrence of pancreatic carcinoma.
Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells.
Increased matrix metalloproteinases 2 and 9 and tissue inhibitor of matrix metalloproteinase 2 expression is associated with progression from vulvar intraepithelial neoplasia to invasive carcinoma.
Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.
Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer.
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Influence of lymphatic endothelial cells on proliferation and invasiveness of esophageal carcinoma cells in vitro and lymphangiogenesis in vivo.
Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells.
Infrequent stromal expression of gelatinase A and intact basement membrane in intraductal neoplasms of the pancreas.
Inhibition activity of sulfated polysaccharide of Sepiella maindroni ink on matrix metalloproteinase (MMP)-2.
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44.
Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation.
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone.
Inhibition of matrix metalloproteinase-2 modulates malignant behaviour of oral squamous cell carcinoma cells.
Inhibition of tumor-cell invasion and gelatinase production in metastatic human gastric-carcinoma cells by retinoic Acid and bestatin.
Inhibitory effects of ubenimex (bestatin) on the invasion of uterine cervical carcinoma cells and their production and activation of gelatinase A.
Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9.
Inostamycin, an inhibitor of cytidine 5'-diphosphate 1,2-diacyl-sn-glycerol (CDP-DG): inositol transferase, suppresses invasion ability by reducing productions of matrix metalloproteinase-2 and -9 and cell motility in HSC-4 tongue carcinoma cell line.
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential.
Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases.
Invasiveness and MMP expression in pancreatic carcinoma.
Investigation of vasculogenic mimicry in sebaceous carcinoma of the eyelid.
Involvement of DPPIV/CD26 in epithelial morphology and suppressed invasive ability in ovarian carcinoma cells.
Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells.
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Isolation and characterization of a high molecular weight type IV collagenase isolated from human carcinoma tissue.
Knockdown of Angiopoietin-2 Suppresses Metastasis in Human Pancreatic Carcinoma by Reduced Matrix Metalloproteinase-2.
Laminin-5 gamma2 chain and matrix metalloproteinase-2 expression in the neoplastic changes of uterine cervical squamous epithelium.
Leptin acts on neoplastic behavior and expression levels of genes related to hypoxia, angiogenesis, and invasiveness in oral squamous cell carcinoma.
Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer.
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.
Levels of neutrophil gelatinase-assosciated lipocalin in patients with head and neck squamous cell carcinoma in Indian population from Haryana state.
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption.
Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Low concentrations of the recombinant toxin protein rLj-RGD3 suppress TNF-?-induced human renal carcinoma cell invasion.
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Marked acceleration of the metastatic phenotype of a rat bladder carcinoma cell line by the expression of human gelatinase A.
Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase.
Matrix metallopeptidase 2 (MMP2) mediates MHC class I polypeptide-related sequence A (MICA) shedding in renal cell carcinoma.
Matrix metalloproteinase (MMP-2 and MMP-9) and steroid receptor expressions in feline mammary tumors.
Matrix metalloproteinase 2 and 9 in esophageal cancer.
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Matrix metalloproteinase 9 expression in primary human prostatic adenocarcinoma and benign prostatic hyperplasia.
Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients.
Matrix metalloproteinase-2 (MMP-2): A major player in the progression of systemic malignancies besides endometrial serous carcinomas.
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Matrix metalloproteinase-2 and -9 activities correlate with the disease-free survival of oral squamous cell carcinoma patients.
Matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in sera and urine of patients with renal carcinoma.
Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma.
Matrix metalloproteinase-2 and -9 involvement in canine tumors.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma.
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines.
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Matrix metalloproteinase-9 is a prognostic marker to predict survival of patients who underwent surgery due to rectal carcinoma.
Matrix metalloproteinases (MMPs) and inhibitor of metalloproteinases (TIMP) mRNA and protein expression in laryngeal squamous cell carcinoma.
Matrix metalloproteinases 2 and 9 immunoexpression in prostate carcinoma at the positive margin of radical prostatectomy specimens.
Matrix metalloproteinases and their inhibitors.
Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer.
Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.
Matrix metalloproteinases expressed in squamous cell carcinoma of the oral cavity: correlation with clinicopathologic features and neo-adjuvant chemotherapy response.
Matrix metalloproteinases in carcinoma of unknown primary.
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma.
Matrix-metalloproteinases in bronchopulmonary carcinomas.
May High MMP-2 and TIMP-2 Expressions Increase or Decrease the Aggressivity of Oral Cancer?
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion.
Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis.
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Metalloproteinases and tissue inhibitor of metalloproteinase 1 (TIMP-1) in endometrial flushings from pre- and post-menopausal women and from women with endometrial adenocarcinoma.
Metastatic dissemination of human ovarian epithelial carcinoma is promoted by alpha2beta1-integrin-mediated interaction with type I collagen.
MicroRNA-132 suppresses migration and invasion of renal carcinoma cells.
miR-29b inhibits the progression of esophageal squamous cell carcinoma by targeting MMP-2.
MMP production in human fibrosarcoma cells and their invasiveness are regulated by group IB secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2.
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
MMP-2 and DcR3 expression in esophageal cancer tissue and correlation with patient survival.
MMP-2 and MMP-9 as prognostic markers for the early detection of urinary bladder cancer.
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
MMP-2 as a putative biomarker for carcinomatosis in gastric cancer.
MMP-2 release and activation in ovarian carcinoma: the role of fibroblasts.
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
MMP-2, TIMP-1, E-cadherin, and beta-catenin expression in endometrial serous carcinoma compared with low-grade endometrial endometrioid carcinoma and proliferative endometrium.
MMP-2, TIMP-2 and CD44v6 Expression in Non-small-cell Lung Carcinomas.
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits.
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus.
Modulation of cell growth and matrix metalloproteinase-2 activation of oral squamous cell carcinoma as a function of culture condition with type I collagen.
Modulation of human renal cell carcinoma 786-0 MMP-2 and MMP-9 activity by inhibitors and inducers in vitro.
Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice.
Molecular pathways involved in crosstalk between cancer cells, osteoblasts and osteoclasts in the invasion of bone by oral squamous cell carcinoma.
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.
Neutrophil Gelatinase Associated Lipocalin is an Independent Predictor of Poor Prognosis in Cases of Papillary Renal Cell Carcinoma.
Nicotinamide N-methyltransferase Induces Cellular Invasion through Activating Matrix Metalloproteinase-2 Expression in Clear Cell Renal Cell Carcinoma Cells.
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.
O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2.
Occurrence of an active form of gelatinase in human gastric and colorectal carcinoma tissues.
Of humans and hamsters: A comparative evaluation of carcinogen activation, DNA damage, cell proliferation, apoptosis, invasion, and angiogenesis in oral cancer patients and hamster buccal pouch carcinomas.
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.
Ovarian carcinoma regulation of matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase through beta1 integrin.
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells.
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Overexpression of MMP-2 and MMP-9 in squamous cell carcinomas of immunosuppressed patients.
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
p21(WAF-1/CIP-1), a downstream regulator of functional p53 loss, in transitional cell carcinoma of urothelium.
p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.
Pancreatic Stellate Cells Activation and Matrix Metallopeptidase 2 Expression Correlate With Lymph Node Metastasis in Pancreatic Carcinoma.
Papers to appear in forthcoming issues
Paracrine communication between malignant and non-malignant prostate epithelial cells in culture alters growth rate, matrix protease secretion and in vitro invasion.
Participation of fibroblasts in MMP-2 binding and activation on the surface of oral squamous cell carcinoma cells.
PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma.
Periacinar Retraction Clefting in Nonneoplastic and Neoplastic Prostatic Glands: Artifact or Molecular Involvement.
Periostin promotes migration and invasion of renal cell carcinoma through the integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway.
Peritumoral Clefting and Expression of MMP-2 and MMP-9 in Basal Cell Carcinoma of the Skin.
Phenotypes of human esophageal squamous cell carcinoma based on matrix metalloproteinase production.
Pinosylvin reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway.
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-?B-dependent transcription.
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Prediction of metastasis in oral squamous cell carcinoma through phenotypic evaluation and gene expression of E-cadherin, ?-catenin, matrix metalloproteinase-2, and matrix metalloproteinase-9 biomarkers with clinical correlation.
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NF kappa B.
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Production of matrix metalloproteinase 2 (gelatinase/type IV collagenase) and 3 (stromelysin) by cultured oral squamous cell carcinoma.
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Prognosis of gastric carcinoma revealed by interactions between tumor cells and basement membrane.
Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion.
Prognostic molecular markers in head and neck squamous cell carcinoma in a New Zealand population: matrix metalloproteinase-2 and sialyl Lewis x antigen.
Prognostic relevance of MMP-2 (72-kD collagenase IV) in gastric cancer.
Prognostic relevance of serum levels of the angiogenic peptide bFGF in advanced carcinoma of the head and neck treated by primary radiochemotherapy.
Prognostic significance of CXCR-4 expression in oral squamous cell carcinoma.
Prognostic significance of matrix metalloproteinases 2 and 9 in bladder cancer.
Prognostic significance of matrix metalloproteinases 2 and 9 in endometrial cancer.
Prognostic significance of matrix metalloproteinases-2 activation ratio in renal cell carcinoma.
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Prognostic significance of TIMP-2, MMP-2, and MMP-9 on high-grade serous ovarian carcinoma using digital image analysis.
Prognostic stratification of stage IIIA pN2 non-small cell lung cancer by hierarchical clustering analysis of tissue microarray immunostaining data: an Alpe Adria Thoracic Oncology Multidisciplinary Group study (ATOM 014).
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Prognostic value of matrix metalloproteinases in oral squamous cell carcinoma.
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Prominent expression of metalloproteinases in early stages of ovarian tumorigenesis.
Prostate carcinoma and green tea: (-)epigallocatechin-3-gallate inhibits inflammation-triggered MMP-2 activation and invasion in murine TRAMP model.
Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate.
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Purification and characterization of a two-chain form of tissue inhibitor of metalloproteinases (TIMP) type 2 and a low molecular weight TIMP-like protein.
Quantitative Assessment of the Effects of MMP-2 Polymorphisms on Lung Carcinoma Risk.
Rap2B promotes migration and invasion of human suprarenal epithelioma.
Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues.
Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy.
Redox-regulation of gelatinases during growth of cisplatin-sensitive and resistant Guerin carcinoma.
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.
Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer.
Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts.
Regulation of the Mr 72,000 type IV collagenase by the type I insulin-like growth factor receptor.
Regulatory effect of MiR103 on proliferation, EMT and invasion of oral squamous carcinoma cell through SALL4.
Relationship between metalloprotease expression in tumour and stromal cells and aggressive behaviour in prostate carcinoma: Simultaneous high-throughput study of multiple metalloproteases and their inhibitors using tissue array analysis of radical prostatectomy samples.
Relationship between the Expression of Matrix Metalloproteinase and Clinicopathologic Features in Oral Squamous Cell Carcinoma.
Relationships Between Immunophenotype, Ki-67 Index, Microvascular Density, Ep-CAM/P-cadherin, and MMP-2 Expression in Early-stage Invasive Ductal Breast Cancer.
Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma.
Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential.
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Role of immunohistochemical overexpression of matrix metalloproteinases MMP-2 and MMP-11 in the prognosis of death by ovarian cancer.
Role of matrix metalloproteinase-9 in in vitro invasion of esophageal carcinoma cells.
Role of matrix metalloproteinase-9 in the basement membrane destruction of superficial urothelial carcinomas.
Role of matrix metalloproteinases in colorectal carcinogenesis.
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.
ROS Production and Distribution: A New Paradigm to Explain the Differential Effects of X-ray and Carbon Ion Irradiation on Cancer Stem Cell Migration and Invasion.
S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity.
S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells.
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
Secretion of gelatinases by human pancreatic cancer cell lines: lack of correlation with invasive ability.
Selective gelatinase inhibitor peptide is effective in targeting tongue carcinoma cell tumors in vivo.
Serum Level of Matrix Metalloproteinase-2 and -9 in Patients with Laryngeal Squamous Cell Carcinoma and Clinical Significance.
Serum levels of matrix metalloproteinase-2 and -9 in patients with head and neck squamous cell carcinoma.
Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients.
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Shedding of membrane type 1 matrix metalloproteinase in a human breast carcinoma cell line.
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
Significance of MMP-2 expression in prostate cancer: an immunohistochemical study.
Similarities of in situ mRNA expression between gelatinase A (MMP-2) and type I procollagen in human gastrointestinal carcinoma: comparison with granulation tissue reaction.
Skp2 Regulates the Expression of MMP-2 and MMP-9, and Enhances the Invasion Potential of Oral Squamous Cell Carcinoma.
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma.
Sodium caffeate induces endothelial cell apoptosis and inhibits VEGF expression in cancer cells.
Soluble EMMPRIN (extra-cellular matrix metalloproteinase inducer) stimulates the migration of HEp-2 human laryngeal carcinoma cells, accompanied by increased MMP-2 production in fibroblasts.
Squamous cell carcinoma growth in mice and in culture is regulated by c-Jun and its control of matrix metalloproteinase-2 and -9 expression.
Stage-specific expression analysis ofMMP-2 & MMP-9 in laryngeal carcinoma.
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Substance P accelerates the progression of human esophageal squamous cell carcinoma via MMP-2, MMP-9, VEGF-A, and VEGFR1 overexpression.
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion.
Survivin, bcl-2 and matrix metalloproteinase-2 enhance progression of clear cell- and serous-type ovarian carcinomas.
SUZ12 RNA interference inhibits the invasion of gastric carcinoma cells.
SUZ12 RNA Interference Inhibits the Invasion of Gastric Carcinoma Cells.
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Taxifolin inhibits the scar cell carcinoma growth by inducing apoptosis, cell cycle arrest and suppression of PI3K/AKT/mTOR pathway.
The aqueous extract of Prunella vulgaris suppresses cell invasion and migration in human liver cancer cells by attenuating matrix metalloproteinases.
The basement membrane and its involvement in carcinoma cell invasion.
The clinical role of phospholipase A2 isoforms in advanced-stage ovarian carcinoma.
The Effect of TGF-beta(2) on MMP-2 Production and Activity in Highly Metastatic Human Bladder Carcinoma Cell Line 5637.
The enamel matrix derivative (Emdogain) enhances human tongue carcinoma cells gelatinase production, migration and metastasis formation.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The Expression and Clinical Significance of TGF-B1 and MMP2 in Human Renal Clear Cell Carcinoma.
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor 2 in pancreatic ductal and ampullary carcinoma and their relation to angiogenesis and clinicopathological parameters.
The expression of six biomarkers in the four most common ovarian cancers: correlation with clinicopathological parameters.
The expression of STAT3, BCL-XL and MMP-2 proteins in colon adenocarcinomas and their relationship with prognostic factors.
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
The immunohistochemical characterization of MMP-2, MMP-10, TIMP-1, TIMP-2, and podoplanin in oral squamous cell carcinoma.
The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma.
The inhibitory effects of capillarisin on cell proliferation and invasion of prostate carcinoma cells.
The Mechanism of Asparagine Endopeptidase in the Progression of Malignant Tumors: A Review.
The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma.
The prognostic value of p53, Ki-67 and matrix metalloproteinases MMP-2 and MMP-9 in transitional cell carcinoma of the renal pelvis and ureter.
The prognostic value of the expression of collagenase IV, cathepsin D and metallothionein in squamous cell carcinomas of the skin determined by immunohistochemistry.
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma.
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Tissue inhibitor of metalloproteinase-2 as a multifunctional molecule of which the expression is associated with adverse prognosis of patients with urothelial bladder carcinomas.
Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma.
Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma.
Transcriptional expression of the genes implicated in angiogenesis and tumor invasion in cervical carcinomas.
Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells.
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Tumor-specific urinary matrix metalloproteinase fingerprinting: identification of high molecular weight urinary matrix metalloproteinase species.
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Type IV collagenase in squamous cell and basal cell skin carcinomas.
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma.
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.
White matter microglia produce membrane-type matrix metalloprotease, an activator of gelatinase A, in human brain tissues.
WISP-1 overexpression upregulates cell proliferation in human salivary gland carcinomas via regulating MMP-2 expression.
XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9.
Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis.
[An experimental study of matrix metalloproteinase inhibitor BB-94 inhibits the invasion and metastasis of the human salivary adenoid cystic carcinoma in vitro and in vivo]
[An immunohistochemical double labelling study on type IV collagenase and basement membrane in human colonic carcinoma]
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
[Correlation of expression of vascular endothelial growth factor and matrix matalloproteinase-2 to invasion of ovarian tumor cells in vitro]
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
[Effect of bone morphogenetic protein-2 on the expression of membrane Type 1-matrix metalloproteinase in human A549 lung carcinoma cells]
[Effect of cyclooxygenase-2 inhibitor on expression of matrix metalloproteinase-2 and invasion of tongue squamous cell carcinoma cell line Tca8113].
[Expression and clinical significance of CD147 and MMP-2 ?in squamous cell carcinoma and adenocarcinoma of the lungs].
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
[Expression of matrix metalloproteinase 2 in oral verruvous carcinoma and squamous cell carcinoma]
[Expression of matrix metalloproteinase-2 and insulin-like growth factor-1 in gastric carcinoma and their clinicopathological significance].
[Expression of matrix metalloproteinase-2 in hypopharyngeal carcinoma and its clinical significance]
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
[Expression of matrix metalloproteinase-2,9 in hypopharyngeal carcinoma and its relationship with lymphatic metastasis]
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
[Expression of nm23/NDPK, integrin, type IV collagenase and uPA in transplanted tumors with various metastatic potential in nude mice and surgical specimens]
[Expression of S100A4 in esophageal squamous cell carcinoma and its relation to tumor invasion and metastasis]
[Expressions and clinical significance of vasculogenic mimicry and related protein Mig-7 and MMP-2 in gastric carcinoma].
[Expressions and significances of CD147, OPN and MMP-2 in oral squamous cell carcinoma].
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
[Expressions of discoidin domain receptor 1 and matrix metalloproteinase 2 in salivary gland adenoid cystic carcinoma and clinical significance].
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
[Gelatinases A and B and their endogenous regulators in the corpus uteri in squamous cell cervical carcinoma].
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
[Inhibitory effect of anti-type IV collagenase intrabody on invasiveness of human pulmonary giant cell carcinoma PG cells in vitro]
[Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3]
[Interactions of ovarian carcinoma cells and human peritoneal mesothelial cells involved in matrix metalloproteinases expressions of ovarian carcinoma cells]
[Interference of HIF-1alpha by RNA reduces the expression of matrix metalloproteinase-2 in human cervical carcinoma HeLa cells]
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
[Matrix metalloproteinases (MMP)--MMP-1,-2,-9 and its endogenous activity regulators in transformed by E7 oncogene HPV16 and HPV18 cervical carcinoma cell lines].
[Matrix metalloproteinases and their tissue inhibitors in malignancies of the female genital tract]
[miR-143 inhibits proliferation and invasion of hepatocellular carcinoma cells via down-regulation of TLR2 expression].
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
[Polymorphism of metalloproteinases MMP-1 and MMP-2 in risk of laryngeal cancer].
[Postoperative prognostic factors for carcinoma of the thoracic esophagus]
[Predictive value of serum levels of basic fibroblast growth factor, vascular endothelial growth factor and matrix metalloproteinase-2 in advanced carcinomas of the head and neck]
[Relationship of local recurrence with the expression of Survivin and MMP-2 in laryngeal carcinoma and its surgical margins].
[Relationship of the disturbed balance between matrix metalloproteinases and their tissue inhibitors and the invasion of malignant salivary gland tumours]
[Role of matrix metalloproteinases (MMPs) in tumor invasion and metastasis: serial studies on MMPs and TIMPs]
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
[Role of tissue factor in the invasion of cultured human colon carcinoma cells and its correlation with matrix metalloproteinases]
[Role of type IV collagenase in tumor cell invasion and effect of laminin on invasive potential in bile duct carcinoma]
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
[Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]
[Stromal proteases in the progression of breast cancer]
[Study of type I and IV collagenase activity in human thyroid diseases]
[The effect of tissue inhibitor of metalloproteinase-2 gene (TIMP-2 gene) on gastric carcinoma cells in vitro and in vivo]
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
[The expression of MMP-2 and MMP-9 in adenoid cystic carcinoma of lacrimal gland].
[The expression of MMP-2, -9 in the uterine leiomyoma and its significance in prognosis].
[The expression of MMP-2, E-cadherin in supraglottic carcinoma and their relationship with cervical lymph nody metastasis]
[THE MODE OF CLARIFYING DIAGNOSTIC OF PROGRESSING FORMS OF OVARIAN CARCINOMA].
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
[Type IV collagenase expression in human prostate carcinoma cell lines with different metastasis potentials]
Carcinoma in Situ
Biomarker expression in normal fimbriae: Comparison of high- and low-grade serous ovarian carcinoma.
Expression profile of epithelial-mesenchymal transition markers in non-muscle-invasive urothelial carcinoma of the bladder: correlation with intravesical recurrence following transurethral resection.
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
Carcinoma, Acinar Cell
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Carcinoma, Adenoid Cystic
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Expression of matrix metalloproteinases (MMPs-2, -7, -9, and -26) and tissue inhibitors of metalloproteinases (TIMPs-1 and -2) in pleomorphic adenomas and adenoid cystic carcinomas.
Expression of RECK and MMP-2 in salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis.
[An experimental study of matrix metalloproteinase inhibitor BB-94 inhibits the invasion and metastasis of the human salivary adenoid cystic carcinoma in vitro and in vivo]
[Expressions of discoidin domain receptor 1 and matrix metalloproteinase 2 in salivary gland adenoid cystic carcinoma and clinical significance].
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
[The expression of MMP-2 and MMP-9 in adenoid cystic carcinoma of lacrimal gland].
Carcinoma, Adenosquamous
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
Carcinoma, Basal Cell
Desmoplastic basal cell carcinomas possess unique basement membrane-degrading properties.
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma.
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.
Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients.
Peritumoral Clefting and Expression of MMP-2 and MMP-9 in Basal Cell Carcinoma of the Skin.
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Carcinoma, Ductal
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Expression of cyclooxygenase-2 and its relation to histological grade, inducible nitric oxide synthase, matrix metalloproteinase-2, CD-34, Caspase-3, and CD8 in invasive ductal carcinoma of the breast.
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast.
Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast.
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis.
Seprase, a membrane-bound protease, is overexpressed by invasive ductal carcinoma cells of human breast cancers.
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Serum MMPs and TIMPs: May be predictors of breast carcinogenesis?
Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast.
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
Carcinoma, Embryonal
Increased expression of the matrix metalloproteinase 2 in differentiating Tera 2 human embryonal carcinoma cells.
Mono-(2-Ethylhexyl) Phthalate (MEHP) Promotes Invasion and Migration of Human Testicular Embryonal Carcinoma Cells.
Carcinoma, Endometrioid
A quantitative evaluation of active gelatinolytic sites in uterine endometrioid adenocarcinoma using film in situ zymography: association of stronger gelatinolysis with myometrial invasion.
CD147 (EMMPRIN) and matrix metalloproteinase-2 expression in uterine endometrioid adenocarcinoma.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma.
Matrix metalloproteinases 2 and 9, E-cadherin, and beta-catenin expression in endometriosis, low-grade endometrial carcinoma and non-neoplastic eutopic endometrium.
MMP-2, TIMP-1, E-cadherin, and beta-catenin expression in endometrial serous carcinoma compared with low-grade endometrial endometrioid carcinoma and proliferative endometrium.
Prognostic significance of matrix metalloproteinases 2 and 9 in endometrial cancer.
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Prognostic value of matrix metalloproteinase-2 (MMP-2) expression in endometrial endometrioid adenocarcinoma.
[Expression and significance of Twist1 and MMP-2 in endometrial endometrioid adenocarcinoma].
Carcinoma, Giant Cell
[Inhibitory effect of anti-type IV collagenase intrabody on invasiveness of human pulmonary giant cell carcinoma PG cells in vitro]
Carcinoma, Hepatocellular
(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
?-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways.
A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription.
Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis.
Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways.
An absolute role of the PKC-dependent NF-kappaB activation for induction of MMP-9 in hepatocellular carcinoma cells.
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Anti-Invasion and Antimetastatic Effects of Porcine Recombinant NK-lysin on SMMC-7721 Human Hepatocellular Carcinoma Cells.
Anti-invasive activity of anthocyanins isolated from Vitis coignetiae in human hepatocarcinoma cells.
Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and e-cadherin.
Apicidin-resistant HA22T hepatocellular carcinoma cells strongly activated the Wnt/?-catenin signaling pathway and MMP-2 expression via the IGF-IR/PI3K/Akt signaling pathway enhancing cell metastatic effect.
Arsenic trioxide inhibits metastatic potential of mouse hepatoma H22 cells in vitro and in vivo.
Assessment of the clinical significance of serum matrix metalloproteinases MMP-2 and MMP-9 in patients with various chronic liver diseases and hepatocellular carcinoma.
Association of E-cadherin, matrix metalloproteinases, and tissue inhibitors of metalloproteinases with the progression and metastasis of hepatocellular carcinoma.
Autocrine motility factor enhances hepatoma cell invasion across the basement membrane through activation of beta1 integrins.
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma.
Baicalein Inhibits the Invasion and Metastatic Capabilities of Hepatocellular Carcinoma Cells via Down-Regulation of the ERK Pathway.
Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model.
Caffeic acid phenethyl ester inhibits invasion and expression of matrix metalloproteinase in SK-Hep1 human hepatocellular carcinoma cells by targeting nuclear factor kappa B.
Caffeoyl pyrrolidine derivative LY52 inhibits hepatocellular carcinoma invasion via suppressing matrix metalloproteinase-2.
CD147, MMP-2, MMP-9 and MVD-CD34 are Significant Predictors of Recurrence After Liver Transplantation in Hepatocellular Carcinoma Patients.
Cellular distribution of 92-kd type IV collagenase/gelatinase B in human hepatocellular carcinoma.
Claudin-1 acts through c-Abl-protein kinase Cdelta (PKCdelta) signaling and has a causal role in the acquisition of invasive capacity in human liver cells.
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Clinical value of apoptosis and angiogenesis factors in estimating the prognosis of hepatocellular carcinoma.
Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Correction: liang, j., et Al. Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and e-cadherin. Int. J. Mol. Sci. 2012, 13, 10594-10607.
CXCL10 accelerates EMT and metastasis by MMP-2 in hepatocellular carcinoma.
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Down-regulation of osteopontin inhibits metastasis of hepatocellular carcinoma cells via a mechanism involving MMP-2 and uPA.
Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells.
Downregulation of the Notch signaling pathway inhibits hepatocellular carcinoma cell invasion by inactivation of matrix metalloproteinase-2 and -9 and vascular endothelial growth factor.
Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo.
Effect of all trans-retinoic acid on the secretion of IV collagenase.
Effect of c-myc, Ki-67, MMP-2 and VEGF expression on prognosis of hepatocellular carcinoma patients undergoing tumor resection.
Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and staging.
Elevated plasma levels of matrix metalloproteinase-9 (92-kd type IV collagenase/gelatinase B) in hepatocellular carcinoma.
Evaluation of anti-invasion effect of resveratrol and related methoxy analogues on human hepatocarcinoma cells.
Evaluation of hepatocellular carcinoma aggressiveness by a panel of extracellular matrix antigens.
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Exogenous hydrogen sulfide exerts proliferation/anti-apoptosis/angiogenesis/migration effects via amplifying the activation of NF-?B pathway in PLC/PRF/5 hepatoma cells.
Expression of Concern: CD147, MMP-2, MMP-9 and MVD-CD34 are significant predictors of recurrence after liver transplantation in hepatocellular carcinoma patients.
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Expression of matrix metalloproiteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in hepatocellular carcinoma tissue, compared with the surrounding non-tumor tissue.
Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance.
Expression of vascular endothelial growth factor and matrix metalloproteinase-2 correlates with the invasion and metastasis of hepatocellular carcinoma.
Factors of transforming growth factor beta signalling are co-regulated in human hepatocellular carcinoma.
Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma.
Functional polymorphisms in the promoters of MMP-1, MMP-2, MMP-3, MMP-9, MMP-12 and MMP-13 are not associated with hepatocellular carcinoma risk.
Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1{alpha}, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma.
Hepatocarcinoma cell lines down-regulate matrix metalloproteinase-2 expression in human hepatic myofibroblasts.
HGF, MET, and matrix-related proteases in hepatocellular carcinoma, fibrolamellar variant, cirrhotic and normal liver.
Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.
Immunocytochemical detection of MMP-3 and -10 expression in hepatocellular carcinomas.
In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis.
Increased expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 with tumor dedifferentiation in hepatocellular carcinomas.
Inhibition of MMP-2 Expression Enhances the Anti-tumor Effect of Sorafenib in Hepatocellular Carcinoma by Suppressing PI3K/AKT/mTOR Pathway.
Inhibitory effect of Daesungki-Tang on the invasiveness potential of hepatocellular carcinoma through inhibition of matrix metalloproteinase-2 and -9 activities.
Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma.
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.
Knockdown of Golgi phosphoprotein 73 blocks the trafficking of matrix metalloproteinase-2 in hepatocellular carcinoma cells and inhibits cell invasion.
Localization of messenger RNA for tissue inhibitor of metalloproteinases-1 and type IV collagenases/gelatinases in monkey hepatocellular carcinomas.
Matrix Metalloproteinase 2 Knockdown Suppresses the Proliferation of HepG2 and Huh7 Cells and Enhances the Cisplatin Effect.
Messenger RNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human hepatocellular carcinoma.
miR-100 Suppresses the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells via Targeting CXCR7.
Morin regulates the expression of NF-kappaB-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma.
No association of MMP-7, MMP-8, and MMP-21 polymorphisms with the risk of hepatocellular carcinoma in a Chinese population.
Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines.
Osteopontin promotes hepatocellular carcinoma invasion by up-regulating MMP-2 and uPA expression.
Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.
Overexpression of Tripartite Motif Conaining 55 (TRIM55) Inhibits Migration and Invasion of Hepatocellular Carcinoma (HCC) Cells via Epithelial-Mesenchymal Transition and Matrix Metalloproteinase-2 (MMP2).
Prognostic values of vascular endothelial growth factor and matrix metalloproteinase-2 in hepatocellular carcinoma after radiotherapy.
Protective effects of fermented rice vinegar sediment (Kurozu moromimatsu) in a diethylnitrosamine-induced hepatocellular carcinoma animal model.
Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma.
Serum levels of tissue inhibitor of metalloproteinases-2 and of precursor form of matrix metalloproteinase-2 in patients with liver disease.
Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways.
siRNA suppression of hTERT using activatable cell-penetrating peptides in hepatoma cells.
siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway.
Sonic Hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer.
The effects of propofol on the growth behavior of hepatoma xenografts in Balb/c mice.
The role of Twist1 in hepatocellular carcinoma angiogenesis: a clinical study.
The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection.
Therapeutic effects of tyroserleutide on lung metastasis of human hepatocellular carcinoma SK-HEP-1 and its mechanism affecting ICAM-1 and MMP-2 and -9.
Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma.
Up-regulation of TIMP-1 by genipin inhibits MMP-2 activities and suppresses the metastatic potential of human hepatocellular carcinoma.
Upregulation of IL-6 is involved in moderate hyperthermia induced proliferation and invasion of hepatocellular carcinoma cells.
[Antitumor effects of the immunoconjugate composed of lidamycin and monoclonal antibody 3G11]
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
[Effects of Biejiajian Pills on Wnt signal pathway signal molecules ?-catenin/TCF4 complex activities and downstream proteins cyclin D1 and MMP-2 in hepatocellular carcinoma cells].
[Expression and clinical impact of vascular endothelial growth factor and matrix metalloproteinase-2 in hepatocellular carcinoma]
[Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the hepatocellular carcinomas]
[HBx silencing by shRNA down-regulates MMP-2 expression in human hepatocellular carcinoma cell HepG2.2.15].
[Inhibition of adenovirus-mediated gene transfer of antisense matrix metalloproteinase-2 on hepatocellular carcinoma growth in vivo]
[Recombinant adenovirus vectors carrying antisense matrix metalloproteinase-2 inhibits hepatocellular carcinoma growth in vivo]
[Recombinant adenovirus vectors carrying antisense MMP2 inhibit invasion of HCC cells in vitro]
[Relationship between serum matrix metalloproteinase-2 and metastasis and recurrence following radical hepatic resection in hepatocellular carcinoma]
[Study on effect of arsenic trioxide on adhesion and invasion of human hepatocarcinoma cells in vitro]
[The influence of c-Myc, Ki-67, MMP-2 and VEGF expression on the prognosis of hepatocellular carcinoma patients with tumor resection.]
[The role of MMP-2 in the invasion and metastasis of hepatocellular carcinoma (HCC)]
Carcinoma, Intraductal, Noninfiltrating
Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell death.
Expression of metalloproteases and their inhibitors by tumor and stromal cells in ductal carcinoma in situ of the breast and their relationship with microinvasive events.
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Serum MMPs and TIMPs: May be predictors of breast carcinogenesis?
Study of matrix metalloproteinases and their tissue inhibitors in ductal in situ carcinomas of the breast.
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
Carcinoma, Large Cell
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Carcinoma, Lewis Lung
Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma.
Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.
Carcinoma, Lobular
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
Carcinoma, Medullary
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
[Effects of CD147 gene silencing on protein expression of ANXA2,MMP-2 and TIMP-2 by thyroid medullary carcinoma TT cells and biologic characteristics].
Carcinoma, Mucoepidermoid
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
Carcinoma, Non-Small-Cell Lung
A third-generation matrix metalloproteinase (MMP) inhibitor (ONO-4817) combined with docetaxel suppresses progression of lung micrometastasis of MMP-expressing tumor cells in nude mice.
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma.
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways.
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Capn4 promotes non-small cell lung cancer progression via upregulation of matrix metalloproteinase 2.
Clinicopathologic significance of ?-catenin and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Degradation of tenascin-C and activity of matrix metalloproteinase-2 are associated with tumor recurrence in early stage non-small cell lung cancer.
Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK-Mediated Up-Regulation of MMP-2 and MMP-9.
Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma.
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Expression of metastasis-associated molecules in non-small cell lung cancer and their prognostic significance.
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Expression of type IV collagenase correlates with the expression of vascular endothelial growth factor in primary non-small cell lung cancer.
Fibulin-3 promoter methylation alters the invasive behavior of non-small cell lung cancer cell lines via MMP-7 and MMP-2 regulation.
GOLPH3 Overexpression is Closely Correlated with Poor Prognosis in Human Non-Small Cell Lung Cancer and Mediates its Metastasis Through Upregulating MMP-2 and MMP-9.
ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB.
IL-17A/IL-17RA promotes invasion and activates MMP-2 and MMP-9 expression via p38 MAPK signaling pathway in non-small cell lung cancer.
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer.
Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer.
Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9.
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.
MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-2.
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
MMP-2, TIMP-2 and CD44v6 Expression in Non-small-cell Lung Carcinomas.
Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.
Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer.
Prognostic impact of MMP-2 and MMP-9 expression in pathologic stage IA non-small cell lung cancer.
Prognostic significance of overexpressed matrix metalloproteinase-2, mouse-double minute: 2 homolog and epidermal growth factor receptor in non-small cell lung cancer.
Prognostic value of tissue inhibitor of metalloproteinase-2 expression in patients with non-small cell lung cancer: a systematic review and meta-analysis.
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy.
Salinomycin suppresses TGF-?1-induced EMT by down-regulating MMP-2 and MMP-9 via the AMPK/SIRT1 pathway in non-small cell lung cancer.
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
The Role of Matrix Metalloproteinase 2 on the Survival of Patients with Non-Small Cell Lung Cancer: A Systematic Review with Meta-Analysis.
The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
[Effect of Src tyrosine kinase inhibition on secretion of MMP-2 and MMP-9 by non-small cell lung cancer cells].
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
[Prognostic impact of matrix metalloproteinases 2,9, and 11 in stromal cells stage I non-small cell lung cancer]
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Carcinoma, Ovarian Epithelial
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Expression of metalloproteinases MMP-2 and MMP-9 is associated to the presence of androgen receptor in epithelial ovarian tumors.
Expression of MMP-2, -7, -9, MT1-MMP and TIMP-1 and -2 has no prognostic relevance in patients with advanced epithelial ovarian cancer.
Functional role of matrix metalloproteinases in ovarian tumor cell plasticity.
Gelatinase A-immunoreactive protein in ovarian lesions- prognostic value in epithelial ovarian cancer.
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Prognostic Significance of Ets-1 and the Matrix Metalloproteinase-2 to Tissue Inhibitor of Matrix Metalloproteinase-2 Ratio in Egyptian Epithelial Ovarian Cancer Patients.
Prognostic Significance of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase 2 in Epithelial Ovarian Cancer.
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2.
The activity of medroxyprogesterone acetate, an androgenic ligand, in ovarian cancer cell invasion.
The correlation between immunohistochemical expression of MMP-2 and the prognosis of epithelial ovarian cancer.
The reinforcement of invasion in epithelial ovarian cancer cells by 17 beta-Estradiol is associated with up-regulation of Snail.
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
[Association of SNPs in the promoter of MMP-2 and TIMP-2 genes with epithelial ovarian cancer]
[Clinical significance of matrix metalloproteinase-2 expression in patients with epithelial ovarian tumor]
[Elevated expression of matrix metalloproteinase-9, and fibronectin concentration in recurrent epithelial ovarian cancer]
Carcinoma, Pancreatic Ductal
Infrequent stromal expression of gelatinase A and intact basement membrane in intraductal neoplasms of the pancreas.
Carcinoma, Papillary
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
[Study of matrix metalloproteinase-2 and -9 in thyroid papillary cancer]
Carcinoma, Renal Cell
A Chinese medicine formula Gegen Qinlian decoction suppresses expansion of human renal carcinoma with inhibition of matrix metalloproteinase-2.
Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma.
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Cancer-Specific Survival Stratification Derived from Tumor Expression of Tissue Inhibitor of Metalloproteinase-2 in Non-Metastatic Renal Cell Carcinoma.
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Corrigendum: HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression.
Epigallocatechin-3-gallate inhibits migration and invasion of human renal carcinoma cells by downregulating matrix metalloproteinase-2 and matrix metalloproteinase-9.
Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival.
Expression of matrix metalloproteinase-2 in renal cell carcinoma.
Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma.
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in renal cell carcinoma.
HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Histopathological analysis of angiogenic factors in renal cell carcinoma.
Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways.
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential.
Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases.
Low concentrations of the recombinant toxin protein rLj-RGD3 suppress TNF-?-induced human renal carcinoma cell invasion.
Matrix metallopeptidase 2 (MMP2) mediates MHC class I polypeptide-related sequence A (MICA) shedding in renal cell carcinoma.
Matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in sera and urine of patients with renal carcinoma.
Matrix metalloproteinase-2 and -9 in the sera and in the urine of human oncocytoma and renal cell carcinoma.
Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma.
MicroRNA-132 suppresses migration and invasion of renal carcinoma cells.
Modifications of the radiosensitivity of a renal cancer cell line as a consequence of stable TIMP-1 overexpression.
Modulation of human renal cell carcinoma 786-0 MMP-2 and MMP-9 activity by inhibitors and inducers in vitro.
Monomeric 55-kDa guanidinobenzoatase switches to a serine proteinase activity upon tetramerization. Tetrameric proteinase SP 220 K appears as the native form.
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
Neutrophil Gelatinase Associated Lipocalin is an Independent Predictor of Poor Prognosis in Cases of Papillary Renal Cell Carcinoma.
Nicotinamide N-methyltransferase Induces Cellular Invasion through Activating Matrix Metalloproteinase-2 Expression in Clear Cell Renal Cell Carcinoma Cells.
Osteopontin silencing by small interfering RNA induces apoptosis and suppresses invasion in human renal carcinoma Caki-1 cells.
Periostin promotes migration and invasion of renal cell carcinoma through the integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway.
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-?B-dependent transcription.
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts.
Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential.
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9.
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
Carcinoma, Small Cell
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Immunohistochemical markers of prolonged survival in small cell carcinoma of the lung. An immunohistochemical study.
Carcinoma, Squamous Cell
92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma.
A multicenter study on expressions of vascular endothelial growth factor, matrix metallopeptidase-9 and tissue inhibitor of metalloproteinase-2 in oral and maxillofacial squamous cell carcinoma.
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Activation of Wnt5a-Ror2 signaling associated with epithelial-to-mesenchymal transition of tubular epithelial cells during renal fibrosis.
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Alpha-mangostin suppresses MMP-2 and MMP-9 expression in head and neck squamous carcinoma cells.
Alteration of MMP-2 and -14 expression by imatinib in HPV-positive and -negative squamous cell carcinoma.
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9.
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Critical roles of Wnt5a-Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ?Np63?-mediated epithelial-mesenchymal transition.
Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2.
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells.
Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung.
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP.
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Expression of Gelatinases (MMP-2, MMP-9) and Gelatinase Activator (MMP-14) in Actinic Keratosis and in In Situ and Invasive Squamous Cell Carcinoma.
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Expression of MMP-2, -9 and -13 in cell lines and fresh biopsies of squamous cell carcinomas of the upper aerodigestive tract.
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Expression of type IV collagen, metalloproteinase-2, metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in laryngeal squamous cell carcinomas.
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Immunoexpression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in the metastasis of squamous cell carcinoma of the human tongue.
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer.
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Increased matrix metalloproteinases 2 and 9 and tissue inhibitor of matrix metalloproteinase 2 expression is associated with progression from vulvar intraepithelial neoplasia to invasive carcinoma.
Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Inhibitive effect of celecoxib on the adhesion and invasion of human tongue squamous carcinoma cells to extracellular matrix via down regulation of MMP-2 expression.
Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells.
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Laminin-5 gamma2 chain and matrix metalloproteinase-2 expression in the neoplastic changes of uterine cervical squamous epithelium.
Levels of neutrophil gelatinase-assosciated lipocalin in patients with head and neck squamous cell carcinoma in Indian population from Haryana state.
Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice.
Newt squamous carcinoma proves phylogenetic conservation of tumors as caricatures of tissue renewal.
Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS.
Overexpression of MMP-2 and MMP-9 in squamous cell carcinomas of immunosuppressed patients.
Polysaccharides isolated from Hedyotis diffusa inhibits the aggressive phenotypes of laryngeal squamous carcinoma cells via inhibition of Bcl-2, MMP-2, and ?PA.
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Prognostic molecular markers in head and neck squamous cell carcinoma in a New Zealand population: matrix metalloproteinase-2 and sialyl Lewis x antigen.
Prognostic stratification of stage IIIA pN2 non-small cell lung cancer by hierarchical clustering analysis of tissue microarray immunostaining data: an Alpe Adria Thoracic Oncology Multidisciplinary Group study (ATOM 014).
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
ROS Production and Distribution: A New Paradigm to Explain the Differential Effects of X-ray and Carbon Ion Irradiation on Cancer Stem Cell Migration and Invasion.
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and ?v?6 integrin.
Serum levels of matrix metalloproteinase-2 and -9 in patients with head and neck squamous cell carcinoma.
Squamous cell carcinoma growth in mice and in culture is regulated by c-Jun and its control of matrix metalloproteinase-2 and -9 expression.
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
The prognostic value of CXCR4, MMP-2 and MMP-9 in tongue squamous carcinoma.
The prognostic value of the expression of collagenase IV, cathepsin D and metallothionein in squamous cell carcinomas of the skin determined by immunohistochemistry.
The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
[Effect of cyclooxygenase-2 inhibitor on expression of matrix metalloproteinase-2 and invasion of tongue squamous cell carcinoma cell line Tca8113].
[Expression and clinical significance of CD147 and MMP-2 ?in squamous cell carcinoma and adenocarcinoma of the lungs].
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
[Expression of matrix metalloproteinase 2 in oral verruvous carcinoma and squamous cell carcinoma]
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
Carcinoma, Transitional Cell
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Expression of metalloproteinase-2, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in transitional cell carcinoma of upper urinary tract: correlation with tumor stage and survival.
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.
p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.
Papers to appear in forthcoming issues
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Role of matrix metalloproteinase-9 in the basement membrane destruction of superficial urothelial carcinomas.
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
The prognostic value of p53, Ki-67 and matrix metalloproteinases MMP-2 and MMP-9 in transitional cell carcinoma of the renal pelvis and ureter.
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
[Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]
Carcinoma, Verrucous
Immunohistochemical study of p53, Ki-67, MMP-2 and MMP-9 expression at invasive front of squamous cell and verrucous carcinoma in oral cavity.
Carcinosarcoma
Inhibition of angiogenesis by anthracyclines and titanocene dichloride.
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
Cardiac Output, Low
Latent AKI is… still AKI: the quantification of the burden of renal dysfunction.
Cardiomegaly
Aberrant gene expression of heparanase in ventricular hypertrophy induced by monocrotaline in rats.
Activation of matrix metalloproteinase dilates and decreases cardiac tensile strength.
Crosstalk between obesity and MMP-9 in cardiac remodelling -a cross-sectional study in apparent treatment-resistant hypertension.
Effect of phentolamine on myocardial extracellular matrix of cardiac remodeling in rats.
Effects of pressure overload on extracellular matrix expression in the heart of the atrial natriuretic peptide-null mouse.
Efficacy of nobiletin, a citrus flavonoid, in the treatment of the cardiovascular dysfunction of diabetes in rats.
Hydrogen sulfide mitigates transition from compensatory hypertrophy to heart failure.
Increased Circulating Tissue Inhibitor of Metalloproteinase-2 Is Associated With Resistant Hypertension.
Induction of heparanase gene expression in ventricular myocardium of rats with isoproterenol-induced cardiac hypertrophy.
Interstitial remodeling in beta1-adrenergic receptor transgenic mice.
Investigation of MMP-2 and MMP-9 activities in canine sera with dilated cardiomyopathy.
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
Metformin Inhibits Isoproterenol-induced Cardiac Hypertrophy in Mice.
MMP-2 in the left rat ventricle is increased by growth hormone.
MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Periodontitis and myocardial hypertrophy.
Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of SGK-1.
Targeted deletion of matrix metalloproteinase 2 ameliorates myocardial remodeling in mice with chronic pressure overload.
Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis.
Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.
Cardiomyopathies
A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers.
Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy.
Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation.
Biomarkers in Trypanosoma cruzi-infected and uninfected individuals with varying severity of cardiomyopathy in Santa Cruz, Bolivia.
Comparison of levels of matrix metalloproteinase-2 and -3 in patients with ischemic cardiomyopathy versus nonischemic cardiomyopathy.
Effects of benazepril on cardiac fibrosis in STZ-induced diabetic rats.
Matrix Metalloproteinases MMP-1 and MMP-9 and Their Inhibitor TIMP-1 as Markers of Dilated Cardiomyopathy in Patients of Different Age.
Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy.
Role of Matrix Metalloproteinase-2 in the Development of Cyclophosphamide-Induced Cardiomyopathy.
Selective disruption of MMP-2 gene exacerbates myocardial inflammation and dysfunction in mice with cytokine-induced cardiomyopathy.
The roles of MMP-2/TIMP-2 in extracellular matrix remodelling in the hearts of STZ-induced diabetic rats.
Cardiomyopathy, Dilated
Comparison of levels of matrix metalloproteinase-2 and -3 in patients with ischemic cardiomyopathy versus nonischemic cardiomyopathy.
Investigation of MMP-2 and MMP-9 activities in canine sera with dilated cardiomyopathy.
Matrix metalloproteinase (MMP)-9, but not MMP-2, is involved in the development and progression of C protein-induced myocarditis and subsequent dilated cardiomyopathy.
Matrix Metalloproteinases MMP-1 and MMP-9 and Their Inhibitor TIMP-1 as Markers of Dilated Cardiomyopathy in Patients of Different Age.
Plasma profiling determinants of matrix homeostasis in paediatric dilated cardiomyopathy.
Cardiomyopathy, Hypertrophic
Increased circulating matrix metalloproteinase-2 in patients with hypertrophic cardiomyopathy with systolic dysfunction.
Left atrial remodelling in hypertrophic cardiomyopathy: relation with exercise capacity and biochemical markers of tissue strain and remodelling.
Procollagen type I carboxy-terminal propeptide (PICP) and MMP-2 are potential biomarkers of myocardial fibrosis in patients with hypertrophic cardiomyopathy.
Cardiotoxicity
Acute doxorubicin-induced cardiotoxicity is associated with matrix metalloproteinase-2 alterations in rats.
Enhanced gene expression of myocardial matrix metalloproteinases 2 and 9 after acute treatment with doxorubicin in mice.
Erythropoietin Modulates Imbalance of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in Doxorubicin-induced Cardiotoxicity.
MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodeling.
Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2.
Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production.
Cardiovascular Diseases
Activation of intracellular matrix metalloproteinase-2 by reactive oxygen-nitrogen species: consequences and therapeutic strategies in the heart.
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Anti-apolipoprotein A-1 IgG predicts major cardiovascular events in patients with rheumatoid arthritis.
Association between plasma neutrophil gelatinase associated lipocalin level and obstructive sleep apnea or nocturnal intermittent hypoxia.
Association of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 With Endothelial Dysfunction, Cardiovascular Disease Risk Factors and thrombotic events in Children With End-stage Renal Disease.
Chinese Yellow Wine and Red Wine Inhibit Matrix Metalloproteinase-2 and Improve Atherosclerotic Plaque in LDL Receptor Knockout Mice.
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Determinants of circulating matrix metalloproteinase-2 and pregnancy-associated plasma protein-A in patients with chronic kidney disease.
Development of anti-matrix metalloproteinase-2 (MMP-2) nanobodies as potential therapeutic and diagnostic tools.
Effect of Angiotensin II on Matrix Metalloproteinase-2 Secretion in Human Umbilical Vein Endothelial Cells.
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs).
Elastin Degradation Is Associated With Progressive Aortic Stiffening and All-Cause Mortality in Predialysis Chronic Kidney Disease.
Elevated concentrations of serum matrix metalloproteinase-2 and -9 and their associations with circulating markers of cardiovascular diseases in chronic arsenic-exposed individuals.
Endogenous nitric oxide formation correlates negatively with circulating matrix metalloproteinase (MMP)-2 and MMP-9 levels in black subjects.
Extrinsic coagulation pathway activation and metalloproteinase-2/TIMPs system are related to oxidative stress and atherosclerosis in hemodialysis patients.
Increase in MMP-2 activity in overweight and obese women is associated with menopausal status.
Increased Matrix Metalloproteinase 2 Activity in the Human Internal Mammary Artery Is Associated with Ageing, Hypertension, Diabetes and Kidney Dysfunction.
Increased plasma activity of metalloproteinase 2 in women with metabolic syndrome.
Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?
Matrix metalloproteinase 9 polymorphisms and systemic lupus erythematosus: correlation with systemic inflammatory markers and oxidative stress.
Matrix metalloproteinase-2 (MMP-2) gene polymorphism and cardiovascular comorbidity in type 2 diabetes patients.
Matrix metalloproteinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMP-2 level and increased risk of cardiovascular disease in systemic lupus erythematosus patients.
Matrix Metalloproteinases are Involved in Cardiovascular Diseases.
Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease.
MiR-29b mimics promotes cell apoptosis of smooth muscle cells via targeting on MMP-2.
MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
OS 15-02 MATRIX METALLOPROTEINASE 2 KNOCKOUT PROTECTS FROM ANGIOTENSIN II-INDUCED VASCULAR INJURY IN PART VIA INHIBITION OF EGFR AND ERK1/2 ACTIVATION.
Periodontal Condition and Immunological Aspects of Individuals Hospitalized in the Intensive Care Unit.
The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2.
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
The role of neutrophil gelatinase associated lipocalin (NGAL) as biological constituent linking depression and cardiovascular disease.
Two MMP-2 promoter polymorphisms (-790T/G and -735C/T) in chronic heart failure.
Vascular Remodeling and Prothrombotic Markers in Subjects Affected by Familial Combined Hyperlipidemia and/or Metabolic Syndrome in Primary Prevention for Cardiovascular Disease.
Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.
Carotid Artery Diseases
Genotype association of C(-735)T polymorphism of the MMP-2 gene with the risk of carotid atherosclerosis-vulnerable plaque in the Han Chinese population.
Serum matrix metalloproteinase-2 and increased oxidative stress are associated with carotid atherosclerosis in hemodialyzed patients.
Urokinase-type plasminogen activator and metalloproteinase-2 are independently related to the carotid atherosclerosis in haemodialysis patients.
Carotid Stenosis
Elevated circulating metalloproteinase 7 predicts recurrent cardiovascular events in patients with carotid stenosis: a prospective cohort study.
Matrix metalloproteinase-2 on activated platelets triggers endothelial PAR-1 initiating atherosclerosis.
MMP and TIMP alterations in asymptomatic and symptomatic severe recurrent carotid artery stenosis.
Neutrophil Gelatinase Associated Lipocalin (NGAL) for Identification of Unstable Plaques in Patients with Asymptomatic Carotid Stenosis.
Neutrophil gelatinase associated lipocalin (NGAL) is elevated in type 2 diabetics with carotid artery stenosis and reduced under metformin treatment.
Serum values of metalloproteinase-2 and metalloproteinase-9 as related to unstable plaque and inflammatory cells in patients with greater than 70% carotid artery stenosis.
Carpal Tunnel Syndrome
MMP-2 expression is associated with rapidly proliferative arteriosclerosis in the flexor tenosynovium and pain severity in carpal tunnel syndrome.
Cataract
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Altered expression of transforming growth factor beta 1 and matrix metalloproteinase-9 results in elevated intraocular pressure in mice.
Association between MMP-2 gene polymorphism and cataract susceptibility: A protocol for systematic review and meta-analysis.
Correlation between MMP-2 gene polymorphism and cataract susceptibility.
Expression of matrix metalloproteinases of human lens epithelial cells in the cultured lens capsule bag.
Gelatinase B/matrix metalloproteinase-9 provokes cataract by cleaving lens betaB1 crystallin.
Higher aqueous levels of matrix metalloproteinases indicated visual impairment in patients with retina vein occlusion after anti-VEGF therapy.
Higher TGF-?1, TGF-?2, MMP-2 and TIMP-1 Levels in the Aqueous Humor of the Patients with Acute Primary Angle Closure.
Human aqueous humor levels of transforming growth factor-?2: Association with matrix metalloproteinases/tissue inhibitors of matrix metalloproteinases.
Immunoreactivity of ICAM-1, MMP-2, and Nesfatin-1 in lens epithelial cells of patients with diabetes mellitus with or without diabetic retinopathy.
Levels and activation of matrix metalloproteinases in aqueous humor are elevated in uveitis-related secondary glaucoma.
Matrix metalloproteinase-2 and -9 activities in the human lens epithelial cells and serum of steroid induced posterior subcapsular cataracts.
Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma.
MMP-2, MMP-3, TIMP-1, TIMP-2, and TIMP-3 protein levels in human aqueous humor: relationship with axial length.
The expression of cytokines in aqueous humor of high myopic patients with cataracts.
The relationship between gelatinase A activity in aqueous humor and glaucoma.
[Expression and significance of transforming growth factor-beta1, matrix metalloproteinase-2 and its inhibitor in lens epithelial cells of diabetic cataract]
Central Nervous System Diseases
l-Glutamate in Middlebrook 7H9 culture medium upregulates matrix metalloproteinase-2 secretion from human astrocytoma cells.
Cerebral Amyloid Angiopathy
The Interaction of Amyloid ? and the Receptor for Advanced Glycation Endproducts Induces Matrix Metalloproteinase-2 Expression in Brain Endothelial Cells.
Cerebral Hemorrhage
A gelatin in situ-overlay technique localizes brain matrix metalloproteinase activity in experimental focal cerebral ischemia.
Donor spontaneous intracerebral hemorrhage is associated with systemic activation of matrix metalloproteinase-2 and matrix metalloproteinase-9 and subsequent development of coronary vasculopathy in the heart transplant recipient.
Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice.
Effects of minocycline on apoptosis and angiogenesis-related protein expression in a rat model of intracerebral hemorrhage.
Endogenous neurogenesis after intracerebral hemorrhage.
Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage.
Ginsenoside Represses Symptomatic Intracerebral Hemorrhage after Recombinant Tissue Plasminogen Activator Therapy by Promoting Transforming Growth Factor-?1.
Induction of hyperhomocysteinemia models vascular dementia by induction of cerebral microhemorrhages and neuroinflammation.
Intralesional administration of allogeneic bone marrow stromal cells reduces functional deficits after intracerebral hemorrhage.
Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy.
Polymorphisms in the Promoters of the MMP-2 and TIMP-2 Genes Are Associated with Spontaneous Deep Intracerebral Hemorrhage in the Taiwan Population.
Simvastatin improves intracerebral hemorrhage through NF-?B-mediated apoptosis via the MyD88/TRIF signaling pathway.
Timing of serum active MMP-9 and MMP-2 levels in acute and subacute phases after spontaneous intracerebral hemorrhage.
Cerebral Infarction
Carotid thickness and atherosclerotic plaque stability, serum inflammation, serum MMP-2 and MMP-9 were associated with acute cerebral infarction.
Correlation between acute myocardial infarction complicated with cerebral infarction and expression levels of MMP-2 and MMP-9.
Neuroprotection by platelet-activating factor acetylhydrolase in a mouse model of transient cerebral ischemia.
The serum levels of MMP-9, MMP-2 and vWF in patients with low doses of urokinase peritoneal dialysis decreased uremia complicated with cerebral infarction.
White matter damage is associated with matrix metalloproteinases in vascular dementia.
Cerebrovascular Disorders
Effect of dietary ? carotene on cerebral aneurysm and subarachnoid haemorrhage in the brain apo E(-/-) mice.
Increased Levels of Soluble Cluster of Differentiation 40 Ligand, Matrix Metalloproteinase 9, and Matrix Metalloproteinase 2 Are Associated with Carotid Plaque Vulnerability in Patients with Ischemic Cerebrovascular Disease.
Cervical Intraepithelial Neoplasia
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
Comparative study of MMP-2 (matrix metalloproteinase 2) immune expression in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma.
Early acquisition of gelatinolytic activity in carcinogenesis of the uterine cervix.
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Expression of MMP-2, MMP-9, and urokinase-type plasminogen activator in cervical intraepithelial neoplasia.
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Chagas Cardiomyopathy
Biomarkers in Trypanosoma cruzi-infected and uninfected individuals with varying severity of cardiomyopathy in Santa Cruz, Bolivia.
Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy.
Chagas Disease
Differential Expression of Matrix Metalloproteinases 2, 9 and Cytokines by Neutrophils and Monocytes in the Clinical Forms of Chagas Disease.
Matrix metalloproteinases 2 and 9 are differentially expressed in patients with indeterminate and cardiac clinical forms of chagas disease.
MMP-2 and MMP-9 plasma levels are potential biomarkers for indeterminate and cardiac clinical forms progression in chronic Chagas disease.
Sialic acid removal by trans-sialidase modulates MMP-2 activity during Trypanosoma cruzi infection.
Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy.
Chediak-Higashi Syndrome
Giant granules of neutrophils in Chediak-Higashi syndrome are derived from azurophil granules but not from specific and gelatinase granules.
Cheilitis
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Cholangiocarcinoma
Ductular reaction after submassive necrosis in humans. Special emphasis on analysis of ductular hepatocytes.
Expression of epidermal growth factor receptor, apomucins, matrix metalloproteinases, and p53 in rat and human cholangiocarcinoma: appraisal of an animal model of cholangiocarcinoma.
Expression of Matrix Metalloproteinase 2 and Extracellular Matrix Metalloproteinase Inducer are Unfavorable Postoperative Prognostic Factors in Intrahepatic Cholangiocarcinoma.
Expression of matrix metalloproteinase 7 is an unfavorable postoperative prognostic factor in cholangiocarcinoma of the perihilar, hilar, and extrahepatic bile ducts.
Expression of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 and -2 in intraductal and nonintraductal growth type of cholangiocarcinoma.
Inhibitory effect of isomorellin on cholangiocarcinoma cells via suppression of NF-?B translocation, the phosphorylated p38 MAPK pathway and MMP-2 and uPA expression.
Rhinacanthin-C Extracted from Rhinacanthus nasutus (L.) Inhibits Cholangiocarcinoma Cell Migration and Invasion by Decreasing MMP-2, uPA, FAK and MAPK Pathways
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT.
Wip1 is associated with tumorigenity and metastasis through MMP-2 in human intrahepatic cholangiocarcinoma.
Cholangitis, Sclerosing
MMP-2 is a disease-modifying gene in primary sclerosing cholangitis.
Cholecystitis
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Cholera
Elevated cyclic AMP suppresses ConA-induced MT1-MMP expression in MDA-MB-231 human breast cancer cells.
Pituitary adenylate cyclase-activating polypeptide acts synergistically with relaxin in modulating ovarian cell function in rats.
Cholestasis
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.
Increased MMP-7 expression in biliary epithelium and serum underpins native liver fibrosis after successful portoenterostomy in biliary atresia.
Lobe-specific heterogeneity in asymmetric dimethylarginine and matrix metalloproteinase levels in a rat model of obstructive cholestasis.
Opioid system blockade decreases collagenase activity and improves liver injury in a rat model of cholestasis.
Cholestasis, Intrahepatic
Epigallocatechin-3-gallate ameliorates intrahepatic cholestasis of pregnancy by inhibiting matrix metalloproteinase-2 and matrix metalloproteinase-9.
Identification of Matrix Metalloproteinase-2 and 9 as Biomarker of Intrahepatic Cholestasis of Pregnancy.
Cholesteatoma
Association of Matrix Metalloproteinase-2 mRNA Expression with Subtypes of Pediatric Cholesteatoma.
Effect of CT manifestations of cholesteatoma on MMP-2, MMP-9 and IL-6 in the serum of patients.
Evaluation of significant gene expression changes in congenital and acquired cholesteatoma.
Expression of matrix-metalloproteinases and their inhibitors in human cholesteatomas.
Gelatinolytic activity of matrix metalloproteinases 2 and 9 in middle ear cholesteatoma.
Matrix metalloproteinase 2: an important genetic marker for cholesteatomas.
Matrix metalloproteinase-1 in cholesteatoma, middle ear granulations and deep meatal skin: a comparative analysis.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in cholesteatoma and deep meatal skin.
Modeling the cholesteatoma microenvironment: coculture of HaCaT keratinocytes with WS1 fibroblasts induces MMP-2 activation, invasive phenotype, and proteolysis of the extracellular matrix.
TREM-2 promotes acquired cholesteatoma-induced bone destruction by modulating TLR4 signaling pathway and osteoclasts activation.
Up-regulation of matrix metalloprotease-9 in middle ear cholesteatoma--correlations with growth factor expression in vivo?
[Expression of matrix metalloproteinasa-2,9 in cholesteatoma and middle ear cancer]
[Expression of matrix metalloproteinase-2,9 in cholesteatoma from different positions]
Choline Deficiency
Immunohistochemical determination of the extracellular matrix modulation in a rat model of choline-deprived myocardium: the effects of carnitine.
Chondroma
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Chondrosarcoma
Alendronate inhibits cell invasion and MMP-2 secretion in human chondrosarcoma cell line.
AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma.
Anti-tumor effects of a nonsteroidal anti-inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator-activated receptor gamma and suppressing matrix metalloproteinase-2 expression.
Correlation between the histological grade of chondrosarcoma and the expression of MMPs, ADAMTSs and TIMPs.
Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours.
ETV5 as a regulator of matrix metalloproteinase 2 in human chondrosarcoma.
Expression of matrix metalloproteinases 1, 2, 9 and their tissue inhibitor-1 in cartilage-forming osteal tumors.
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas.
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
HGF and c-Met interaction promotes migration in human chondrosarcoma cells.
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Production of matrix metalloproteinases and a metalloproteinase inhibitor by swarm rat chondrosarcoma.
Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells.
Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways.
Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression.
The epigenetic regulation of SOX9 by miR-145 in human chondrosarcoma.
The mir-423-5p/MMP-2 Axis Regulates the Nerve Growth Factor-Induced Promotion of Chondrosarcoma Metastasis.
Thrombin enhanced migration and MMPs expression of human chondrosarcoma cells involves PAR receptor signaling pathway.
Visfatin Promotes the Metastatic Potential of Chondrosarcoma Cells by Stimulating AP-1-Dependent MMP-2 Production in the MAPK Pathway.
WISP-1 increases MMP-2 expression and cell motility in human chondrosarcoma cells.
Chondrosarcoma, Mesenchymal
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Chordoma
Expression of hypoxia-inducible factor-1?, vascular endothelial growth factor and matrix metalloproteinase-2 in sacral chordomas.
Expression of matrix metalloproteinase (MMP)-1, MMP-2, MMP-9, cathepsin B, and urokinase plasminogen activator in non-skull base chordoma.
Chorioamnionitis
Chorioamnionitis and increased neonatal lung lavage fluid matrix metalloproteinase-9 levels: implications for antenatal origins of chronic lung disease.
Low maternal serum matrix metalloproteinase (MMP)-2 concentrations are associated with preterm labor and fetal inflammatory response.
Maternal Betamethasone and Chorioamnionitis Induce Different Collagenases during Lung Maturation in Fetal Sheep.
Premature rupture of the fetal membrane combined with subclinical chorioamnionitis negatively affects pregnancy outcomes by a mechanism associated with reduced levels of matrix metalloproteinase-2.
Protease production by microorganisms associated with reproductive tract infection.
Choriocarcinoma
Cloning of choriocarcinoma cells shows that invasion correlates with expression and activation of gelatinase A.
Expression and importance of matrix metalloproteinase 2 and 9 (MMP-2 and -9) in human trophoblast invasion.
HSPC117 is regulated by epigenetic modification and is involved in the migration of JEG-3 cells.
Low-molecular weight heparin induces in vitro trophoblast invasiveness: role of matrix metalloproteinases and tissue inhibitors.
Matrix metalloproteinases and their inhibitors in gestational trophoblastic diseases and normal placenta.
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells.
p53 Mediates Epidermal Growth Factor (EGF) Induction of MMP-2 Transcription and Trophoblast Invasion.
Reduced expression of tissue inhibitor of metalloproteinase (TIMP)-2 in gestational trophoblastic diseases.
Resistance of malignant trophoblast cells to both the anti-proliferative and anti-invasive effects of transforming growth factor-beta.
Resistin regulates human choriocarcinoma cell invasive behaviour and endothelial cell angiogenic processes.
Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.
Suppression of gelatinase production with decreased invasiveness of choriocarcinoma cells by human recombinant interferon beta.
[Analysis of the mechanism of trophoblast infiltration]
[Regulation of matrix-degrading enzymes in gynecologic cancer tissues and cells]
Choroidal Neovascularization
Matrix metalloproteinase (MMP) expression in experimental choroidal neovascularization.
MMP-2 and MMP-9 synergize in promoting choroidal neovascularization.
The non-antibiotic properties of tetracyclines: Clinical potential in ophthalmic disease.
Chromoblastomycosis
Secretion of five extracellular enzymes by strains of chromoblastomycosis agents.
Chronic Periodontitis
Activation of human matrix metalloproteinase 2 by gingival crevicular fluid and Porphyromonas gingivalis.
Activation of MMP-2 by Porphyromonas gingivalis in human periodontal ligament cells.
Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40 kDa serine protease.
Diabetes may affect the expression of matrix metalloproteinases and their inhibitors more than smoking in chronic periodontitis.
Effect of Azadirachta indica (Neem) and Aloe vera as compared to subantimicrobial dose doxycycline on matrix metalloproteinases (MMP)-2 and MMP-9: An in-vitro study.
Effects of therapy with two combinations of antibiotics on the imbalance of MMP-2÷TIMP-2 in chronic periodontitis.
Expression of matrix metalloproteinases-2, -9 and reversion-inducing cysteine-rich protein with Kazal motifs in gingiva in periodontal health and disease.
Expression of metalloproteinases and their tissue inhibitors in inflamed gingival biopsies.
Gene polymorphisms of matrix metalloproteinase-2, -9 and -12 in periodontal health and severe chronic periodontitis.
Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis.
Increased expression of extracellular matrix metalloproteinase inducer is associated with matrix metalloproteinase-1 and -2 in gingival tissues from patients with periodontitis.
Inhibitory effect of procyanidin oligomer from elm cortex on the matrix metalloproteinases and proteases of periodontopathogens.
Interaction between the Wnt/?-catenin signaling pathway and the EMMPRIN/MMP-2, 9 route in periodontitis.
Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients.
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus.
[Expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model]
Churg-Strauss Syndrome
Modulation of MMP-2 and MMP-9 in Churg-Strauss syndrome respiratory mucosa: potential monitoring parameters.
Cleft Lip
Apoptosis and MMP-2, TIMP-2 expression in cleft lip and palate.
Evaluation of the presence of MMP-2, TIMP-2, BMP2/4, and TGF?3 in the facial tissue of children with cleft lip and palate.
Coinfection
Active form of gelatinases in tear fluidin patients with corneal ulcer or ocular burn.
Helminth Coinfection Is Associated With Enhanced Plasma Levels of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Tuberculous Lymphadenitis.
Levels of Serum Markers of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis C Virus Infection According to HIV Status and Antiretroviral Use.
Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients.
Colic
Detecting early kidney damage in horses with colic by measuring matrix metalloproteinase -9 and -2, other enzymes, urinary glucose and total proteins.
Colitis
Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice.
Comparisons of gut microbiota profiles in wild-type and gelatinase B/matrix metalloproteinase-9-deficient mice in acute DSS-induced colitis.
Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.
Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation.
Genetic Deletion of Tissue Inhibitor of Metalloproteinase-1/TIMP-1 Alters Inflammation and Attenuates Fibrosis in Dextran Sodium Sulphate-induced Murine Models of Colitis.
Increased activity and expression of matrix metalloproteinase-9 in a rat model of distal colitis.
Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease.
Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis.
Matrix metalloproteinase-9 modulates intestinal injury in rats with transmural colitis.
Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis.
Pterostilbene Attenuates High-Fat Diet and Dextran Sulfate Sodium-Induced Colitis via Suppressing Inflammation and Intestinal Fibrosis in Mice.
Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis.
Selective gelatinase blockage ameliorates acute DSS colitis.
Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice.
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.
The distinct roles of MMP-2 and MMP-9 in acute DSS colitis.
The expression of iNOS and nitrotyrosine in colitis and colon cancer in humans.
Colitis, Ischemic
Increased activity and expression of gelatinases in ischemic colitis.
Colitis, Ulcerative
Accuracy of Faecal Calprotectin and Neutrophil Gelatinase B-associated Lipocalin in Evaluating Subclinical Inflammation in UlceRaTIVE Colitis-the ACERTIVE study.
Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice.
Changes in MMP-2, MMP-9, inflammation, blood coagulation and intestinal mucosal permeability in patients with active ulcerative colitis.
Effect of Etiasa on the expression of matrix metalloproteinase-2 and tumor necrosis factor-? in a rat model of ulcerative colitis.
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease.
Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases.
Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease.
Neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 complex as a surrogate serum marker of mucosal healing in ulcerative colitis.
Colonic Neoplasms
A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng.
Anti-beta4 integrin antibodies enhance migratory and invasive abilities of human colon adenocarcinoma cells and their MMP-2 expression.
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
CD155 knockdown promotes apoptosis via AKT/Bcl-2/Bax in colon cancer cells.
Characterization of a profile of the anthocyanins isolated from Vitis coignetiae Pulliat and their anti-invasive activity on HT-29 human colon cancer cells.
Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.
Construction of a recombinant eukaryotic expression vector containing DNM3 gene and its expression in colon cancer cells.
Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor.
Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.
Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions.
Differential inhibition of gelatinase activity in human colon adenocarcinoma cells by Aloe vera and Aloe arborescens extracts.
Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities.
Endocrine gland-derived vascular endothelial growth factor strengthens cell invasion ability via prokineticin receptor 2 in colon cancer cell lines.
Evaluation of the expression of metalloproteinases 2 and 9 and their tissue inhibitors in colon cancer cells treated with phytic acid.
Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer.
Extracellular vesicles carrying miR-193a derived from mesenchymal stem cells impede cell proliferation, migration and invasion of colon cancer by downregulating FAK.
FABP4 promotes invasion and metastasis of colon cancer by regulating fatty acid transport.
Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.
Heated and humidified CO2 pneumoperitoneum inhibits tumour cell proliferation, migration and invasion in colon cancer.
Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts.
Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer.
Immunohistochemically detected high expression of matrix metalloproteinase-2 as predictor of poor prognosis in Duke's B colon cancer.
In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.
Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression.
Inhibition of Experimental Colon Cancer Metastasis by the GABA-Receptor Agonist Nembutal.
Inhibitory effect of a gamma-oryzanol-rich fraction from purple rice extract on lipopolysaccharide-induced metastasis in human colon cancer cells.
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
Klotho suppresses growth and invasion of colon cancer cells through inhibition of IGF1R-mediated PI3K/AKT pathway.
Knockdown GREM1 suppresses cell growth, angiogenesis, and epithelial-mesenchymal transition in colon cancer.
M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer.
M2-like macrophages induce colon cancer cell invasion via matrix metalloproteinases.
Matrix metalloproteinase-2 cleavage of the ?1 integrin ectodomain facilitates colon cancer cell motility.
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and ?-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats.
MicroRNA-340 inhibits the proliferation and promotes the apoptosis of colon cancer cells by modulating REV3L.
MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells.
Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice.
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
p38? MAPK Mediates 17?-Estradiol Inhibition of MMP-2 and -9 Expression and Cell Migration in Human LoVo Colon Cancer Cells.
Phenethyl Isothiocyanate Inhibited Tumor Migration and Invasion via Suppressing Multiple Signal Transduction Pathways in Human Colon Cancer HT29 Cells.
Platelet aggregation-induced by caco-2 cells: regulation by matrix metalloproteinase-2 and adenosine diphosphate.
Polymorphisms in MMP-1, MMP-2, MMP-7, MMP-13 and MT2A do not contribute to breast, lung and colon cancer risk in polish population.
Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer.
Protein arginine methyltransferase 5 is implicated in the aggressiveness of human hepatocellular carcinoma and controls the invasive activity of cancer cells.
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging.
Role of endothelin a receptor in colon cancer metastasis: In vitro and in vivo evidence.
RUNX3 Inhibits the Invasion and Metastasis of Human Colon Cancer HT-29 Cells by Upregulating MMP-2/9.
Silibinin inhibits the invasion of IL-6-stimulated colon cancer cells via selective JNK/AP-1/MMP-2 modulation in vitro.
Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers.
Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase.
Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-?B, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways.
The clinical significance and biological function of tropomyosin 4 in colon cancer.
The expression of STAT3, BCL-XL and MMP-2 proteins in colon adenocarcinomas and their relationship with prognostic factors.
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
The role of gelatinases in colorectal cancer progression and metastasis.
The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology.
Transforming growth factor-beta1 modulates metalloproteinase-2 and -9, nitric oxide, RhoA and alpha-smooth muscle actin expression in colon adenocarcinoma cells.
[Effects of phosphatase of regenerating liver cell-3 gene silence by RNA interference on the expression of matrix metalloproteinases-2,-9 in human colon cancer cells]
[Expression and clinical significance of kisspeptin-1, matrix metalloproteinase-2 and vascular endothelial growth factor in tissue of colon cancer].
[Expression of MMP-2, HIF-1alpha and VEGF in Colon Adenoma and Colon Cancer.]
[State of the liver antioxidant system and content of matrix metalloproteinase-2 of the large intestine under the effect of maleimide derivative in experimental colorectal carcinogenesis in rats].
Colorectal Neoplasms
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
A prospective study of prognostic value of type IV collagenase activity in colorectal cancer tissue.
A single nucleotide polymorphism in the matrix metalloproteinase-2 promoter is associated with colorectal cancer.
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Active MMP-2 effectively identifies the presence of colorectal cancer.
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma.
Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population.
Associations between Single Nucleotide Polymorphisms of MMP2, VEGF, and HIF1A Genes and the Risk of Developing Colorectal Cancer.
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Behaviour of basement membrane antigens in gastric and colorectal cancer. Immunohistochemical study.
Carcinoembryonic antigen and matrix metalloproteinase 2 serum and peritoneal washes concentration in staging and prognosis in colorectal cancer patients.
Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer.
Changes in extracellular matrix in different stages of colorectal cancer and their effects on proliferation of cancer cells.
Characterizing human colorectal carcinomas by proteolytic profile.
Circulating gelatinases and tissue inhibitor of metalloproteinase-1 in colorectal cancer metastatic liver disease.
Clinical relevance of MMP-9, MMP-2, TIMP-1 and TIMP-2 in colorectal cancer.
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Clinicopathological assessment and quantitative estimation of the matrix metalloproteinases MMP-2 and MMP-7 and the inhibitors TIMP-1 and TIMP-2 in colorectal carcinoma tissue samples.
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer.
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Correspondence re: N-B. Liabakk et al., matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res., 56: 190-196, 1966.
Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity.
Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue.
Cyclooxygenase-2 inhibition prevents migration of colorectal cancer cells to extracellular matrix by down-regulation of matrix metalloproteinase-2 expression.
Cyclooxygenase-2/Carbonic anhydrase-IX up-regulation promotes invasive potential and hypoxia survival in colorectal cancer cells.
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors.
Evaluation of the expression of metalloproteinases 2 and 9 and their tissue inhibitors in colon cancer cells treated with phytic acid.
Expression and localization of matrix metalloproteinases and tissue inhibitors of metalloproteinases as a prognostic factor in advanced colorectal carcinomas.
Expression of COX-2, MMP-2 and VEGF in stage II and III colorectal cancer and the clinical significance.
Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa.
Expression of matrix metalloproteinases 2, 7 and 9 in patients with colorectal cancer.
Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage.
Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination.
Genetic Modification of Cell Lines to Enhance Their Metastatic Capability.
Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.
High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma.
High molecular weight coffee melanoidins are inhibitors for matrix metalloproteases.
Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer.
Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG-6 expression in a tumor type-specific manner.
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
Increased activity of matrix metalloproteinase 2 and 9 after hepatic radiofrequency ablation.
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Increased serum type IV collagen 7-S levels in patients with hepatic metastasis.
Increased Sushi repeat-containing protein X-linked 2 is associated with progression of colorectal cancer.
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.
Inhibitory Effects of Dried Longan (Euphoria longana Lam.) Seed Extract on Invasion and Matrix Metalloproteinases of Colon Cancer Cells.
Ito cell morphology, alpha-smooth muscle actin and collagen type IV expression in the liver of patients with gastric and colorectal tumors.
Key enzymes of the extracellular matrix in colorectal cancer.
Knockdown of LI-cadherin alters expression of matrix metalloproteinase-2 and -9 and galectin-3.
Knockdown of Li-cadherin increases metastatic behaviors of LoVo cells.
Laminin-5 gamma 2 chain and matrix metalloproteinase-2 may trigger colorectal carcinoma invasiveness through formation of budding tumor cells.
Letter to the editor: a meta-analysis of MMP-2 expression on the survival of patients with colorectal cancer.
Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer.
Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis.
Matrilysin is associated with progression of colorectal tumor.
Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer.
Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis.
Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients.
Matrix metalloproteinase 2 overexpression and prognosis in colorectal cancer: a meta-analysis.
Matrix metalloproteinase 2 promotes cell growth and invasion in colorectal cancer.
Matrix metalloproteinase-2 (-1306 c>t) promoter polymorphism and risk of colorectal cancer in the Saudi population.
Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) in preoperative serum as independent prognostic markers in patients with colorectal cancer.
Matrix metalloproteinase-2 and -7 expression in colorectal cancer.
Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer.
Matrix Metalloproteinase-2 and -9, Lactate, and Malate Dehydrogenase and Lipid Peroxides in Sera of Patients with Colorectal Carcinoma.
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Matrix metalloproteinase-2 cleavage of the ?1 integrin ectodomain facilitates colon cancer cell motility.
Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer.
Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
Matrix metalloproteinases in Vietnamese patients with colorectal cancer.
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Measuring gelatinase activity in colorectal cancer.
MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling.
MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4.
MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.
MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not.
MMP-2, -3 and TIMP-2, -3 polymorphisms in colorectal cancer in a Chinese Han population: A case-control study.
Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling.
Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells.
Naturally occurring glycyrrhizin triterpene exerts anticancer effects on colorectal cancer cells via induction of apoptosis and autophagy and suppression of cell migration and invasion by targeting MMP-9 and MMP-2 expression.
Netrin-1 plays a role in the effect of moderate exercise on myocardial fibrosis in rats.
Occurrence of an active form of gelatinase in human gastric and colorectal carcinoma tissues.
Plasma gelatinase activity does not reflect disease activity after operation for colorectal cancer.
Plasma levels of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 correlate with disease stage and survival in colorectal cancer patients.
Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects.
Preoperative plasma MMP-2 expression is prognostic in colorectal cancer.
Prognostic and diagnostic implications of MMP-2, MMP-9, and VEGF-? expressions in colorectal cancer.
Prognostic significance of matrix metalloproteinase expression in colorectal carcinomas.
Prognostic significance of matrix metalloproteinase-2, cathepsin D, and tenascin-C expression in colorectal carcinoma.
Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples.
Relationship between single-nucleotide polymorphism of matrix metalloproteinase-2 gene and colorectal cancer and gastric cancer susceptibility: a meta-analysis.
Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel.
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
Serum levels and tissue expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinases 2 (TIMP-2) in colorectal cancer patients.
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase.
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Stromelysin-1 promoter mutations impair gelatinase B activation in high microsatellite instability sporadic colorectal tumors.
Synergistic efficacy of Cullin1 and MMP-2 expressions in diagnosis and prognosis of colorectal cancer.
Targeted MMP-2 responsive chimeric polymersomes for therapy against colorectal cancer.
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis.
The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer.
The role of gelatinase in hepatic metastasis of colorectal cancer.
The role of gelatinases in colorectal cancer progression and metastasis.
Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer.
TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways.
Twist1/2 activates MMP2 expression via binding to its promoter in colorectal cancer.
Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence.
Upregulation of nemo-like kinase is an independent prognostic factor in colorectal cancer.
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis.
[Expression of LOX in Colorectal Cancer Tissues and Its Relationship with Progress and Prognosis].
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
[Expression of MMP-2, MMP-9 and collagen type IV and their relationship in colorectal carcinomas.]
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
[Short hairpin RNA-mediated suvivin gene silencing inhibits invasion and metastasis of human colon carcinoma cell line SW480 in vitro]
[The correlation between polymorphisms of matrix metalloproteinase-2 and -9 genes and colorectal cancer of Chinese patients]
[Type IV collagenase activities in human colorectal cancers and its role in cancer invasion and metastasis]
[Type IV collagenase activities in human colorectal carcinomas and its role in hepatic metastasis: preliminary report]
Common Cold
MicroRNA-124-3p inhibits the growth and metastasis of nasopharyngeal carcinoma cells by targeting STAT3.
Complex Regional Pain Syndromes
Local and Systemic Expression Pattern of MMP-2 and MMP-9 in Complex Regional Pain Syndrome.
Confusion
Areca nut procyanidins prevent ultraviolet light B-induced photoaging via suppression of cyclooxygenase-2 and matrix metalloproteinases in mouse skin.
Conjunctivitis, Allergic
Activation of corneal fibroblast-derived matrix metalloproteinase-2 by tryptase.
Active matrix metalloproteinases in the tear fluid of individuals with vernal keratoconjunctivitis.
Connective Tissue Diseases
Autoactivation profiles of calcium-dependent matrix metalloproteinase-2 and -9 in inflammatory synovial fluid: effect of pyrophosphate and bisphosphonates.
Zymographic analysis of latent and activated forms of matrix metalloproteinase-2 and -9 in synovial fluid: correlation to polymorphonuclear leukocyte infiltration and in response to infection.
Contracture
Effect of Tissue Inhibitors of Metalloproteinases and Matrix Metalloproteinases on Capsular Formation Around Smooth and Textured Silicone Gel Implants.
Gelatinase A activity in Dupuytren's disease.
Matrix metalloproteinases, tissue inhibitors of metalloproteinases, aminoterminal propeptide of procollagen type III, and hyaluronan in sera and tissue of patients with capsular contracture after augmentation with Trilucent breast implants.
Structural and biochemical evaluation of the elbow capsule after trauma.
Corneal Diseases
Altered type VI collagen synthesis by keratoconus keratocytes in vitro.
Corneal Injuries
Expression of matrix metalloproteinases 2 and 9 in experimental corneal injury and fungal keratitis.
Corneal Neovascularization
Controlling herpes simplex virus-induced ocular inflammatory lesions with the lipid-derived mediator resolvin E1.
Corneal angiogenic privilege: angiogenic and antiangiogenic factors in corneal avascularity, vasculogenesis, and wound healing (an American Ophthalmological Society thesis).
Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice.
Diminished corneal angiogenesis in gelatinase A-deficient mice.
Expression of matrix metalloproteinase-2 (MMP-2) and vascular endothelial growth factor (VEGF) in inflammation-associated corneal neovascularization.
Expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in inflammation-induced corneal neovascularization.
Regulation of Matrix Metalloproteinase 2 and 9 in Corneal Neovascularization.
Corneal Ulcer
Active form of gelatinases in tear fluidin patients with corneal ulcer or ocular burn.
Matrix metalloproteinases (MMP-2 and MMP-9) activity in corneal ulcer and ocular surface disorders determined by gelatin zymography.
Coronary Aneurysm
Systemic arterial expression of matrix metalloproteinases 2 and 9 in acute Kawasaki disease.
Coronary Artery Disease
A haplotype constituted of four MMP-2 promoter polymorphisms (-1575G/A, -1306C/T, -790T/G and -735C/T) is associated with coronary triple-vessel disease.
Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A Meta-Analysis.
MMP-2, MMP-9, and TIMP-4 and Response to Aspirin in Diabetic and Nondiabetic Patients with Stable Coronary Artery Disease: A Pilot Study.
Neutrophil Gelatinase Associated Lipocalin (NGAL) as a Biomarker. Does It Apply in Abdominal Aortic Aneurysms? A Review of Literature.
New insights into molecular mechanisms of diffuse coronary ectasiae: a possible role for VEGF.
Plasma matrix metalloproteinase-9 and left ventricular remodelling after acute myocardial infarction in man: a prospective cohort study.
Plasma matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-2, and CD40 ligand levels in patients with stable coronary artery disease.
Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease.
Progression of kidney disease in non-diabetic patients with coronary artery disease: predictive role of circulating matrix metalloproteinase-2, -3, and -9.
Serum levels of gelatinase associated lipocalin as indicator of the inflammatory status in coronary artery disease.
Soluble P-selectin and matrix metalloproteinase 2 levels are elevated in patients with diastolic dysfunction independent of glucose metabolism disorder or coronary artery disease.
The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction.
Urinary levels of matrix metalloproteinase 9 and 2 and tissue inhibitor of matrix metalloproteinase in patients with coronary artery disease.
Vitamin D is related to markers of vulnerable plaque in acute myocardial infarction.
[Changes in serum level of carboxy-terminal telopeptide of type I collagen in patients with coronary heart disease].
Coronary Disease
A haplotype constituted of four MMP-2 promoter polymorphisms (-1575G/A, -1306C/T, -790T/G and -735C/T) is associated with coronary triple-vessel disease.
Angiotensin II Induces an Increase in Matrix Metalloproteinase 2 Expression in Aortic Smooth Muscle Cells of Ascending Thoracic Aortic Aneurysms Through JNK, ERK1/2, and p38 MAPK Activation.
Angiotensin II Induces the Vascular Expression of VEGF and MMP-2 in vivo: Preventive Effect of Red Wine Polyphenols.
Carotid thickness and atherosclerotic plaque stability, serum inflammation, serum MMP-2 and MMP-9 were associated with acute cerebral infarction.
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Elevated circulating levels of matrix metalloproteinase-9 and -2 in patients with symptomatic coronary artery disease.
[Analysis of the gene polymorphism of matrix metalloproteinase-2 and -9 in patients with coronary heart disease]
Coronary Stenosis
Metalloproteases 2 and 9, Lp-PLA(2) and lipoprotein profile in coronary patients.
Cough
Predictors of exacerbations in chronic obstructive pulmonary disease--results from the Bergen COPD cohort study.
COVID-19
Matrix metalloproteinases are involved in the development of neurological complications in patients with Coronavirus disease 2019.
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
Crohn Disease
Elevated plasma gelatinase A (MMP-2) activity is associated with quiescent Crohn's Disease.
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease.
Expression of protease-activated receptor-1 and -2 in orofacial granulomatosis.
Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases.
Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease.
P269. Serum neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 (NGAL-MMP-9) complex as a surrogate marker for mucosal healing in patients with Crohn's disease.
Role of N-acetylcysteine and GSH redox system on total and active MMP-2 in intestinal myofibroblasts of Crohn's disease patients.
Serum Neutrophil Gelatinase B-associated Lipocalin and Matrix Metalloproteinase-9 Complex as a Surrogate Marker for Mucosal Healing in Patients with Crohn's Disease.
Cryptogenic Organizing Pneumonia
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias.
Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases.
Cryptorchidism
Plasma concentration of MMP-1 and MMP-2 in boys with cryptorchidism and its lack of correlation with INSL3 and inhibin B.
Cutis Laxa
Cutis Laxa: analysis of metalloproteinases and extracellular matrix expression by immunohistochemistry and histochemistry.
Regulation of matrix metalloproteinase (MMP) expression in cutis laxa fibroblasts: upregulation of MMP-1, MMP-3 and MMP-9 genes but not of the MMP-2 gene.
Cystadenocarcinoma
72-kilodalton type IV collagenase, type IV collagen, and Ki 67 antigen in serous tumors or the ovary: a clinicopathologic, immunohistochemical, and Serological study.
Increased serum 72 KDa metalloproteinase in serous ovarian tumors: comparison with CA 125.
Cystadenocarcinoma, Serous
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Cystadenoma
72-kilodalton type IV collagenase, type IV collagen, and Ki 67 antigen in serous tumors or the ovary: a clinicopathologic, immunohistochemical, and Serological study.
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Increased serum 72 KDa metalloproteinase in serous ovarian tumors: comparison with CA 125.
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Cystic Fibrosis
Imbalance between 95 kDa type IV collagenase and tissue inhibitor of metalloproteinases in sputum of patients with cystic fibrosis.
Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis.
Study of biological characteristics of Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis and from patients with extra-pulmonary infections.
Cysts
Adhesion molecules, chemokines and matrix metallo-proteinases response after albendazole and albendazole plus steroid therapy in swine neurocysticercosis.
Analyses of matrix metalloproteinases and their inhibitors in cyst fluid of serous ovarian tumors.
Angiogenesis in autosomal-dominant polycystic kidney disease.
Cystic vestibular schwannomas: a possible role of matrix metalloproteinase-2 in cyst development and unfavorable surgical outcome.
Difference in expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with persistent ovarian cysts.
Doxycycline use in patients with lymphangioleiomyomatosis: safety and efficacy in metalloproteinase blockade.
Entamoeba invadens: cysteine protease inhibitors block excystation and metacystic development.
Expression of adhesion molecules, chemokines and matrix metallo- proteinases (MMPs) in viable and degenerating stage of Taenia solium metacestode in swine neurocysticercosis.
Expression of matrix metalloproteinase in the fluids of renal cystic lesions.
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Identification and characterization of gelatinases/type IV collagenases in jaw cysts.
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
Immunohistochemical study of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in pulmonary lymphangioleiomyomatosis (LAM).
Increased expression of intracystic matrix metalloproteinases in brain tumors: relationship to the pathogenesis of brain tumor-associated cysts and peritumoral edema.
Increased matrix metalloproteinase-2 activity induced by TGF-beta 1 in duct cells of human salivary gland is associated with the development of cyst formation in vivo.
Involvement of Matrix Metalloproteinases and their Inhibitors in Bovine Cystic Ovarian Disease.
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.
Membrane vesicles in ovarian cancer fluids: a new potential marker.
Membrane-type-1 matrix metalloproteinase confers tumorigenicity on nonmalignant epithelial cells.
Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo.
Significance of matrix metalloproteinases in the pathophysiology of the ovary and uterus.
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Tubular gelatinase A (MMP-2) and its tissue inhibitors in polycystic kidney disease in the Han:SPRD rat.
Cytomegalovirus Infections
[Effect of cytomegalovirus infection on expression of matrix metalloproteinase-2 in human endothelial cells.]
Dementia
Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia.
Concentrations of Matrix Metalloproteinases and their Tissue Inhibitors in the Cerebrospinal Fluid of Patients with Alzheimer's Disease.
Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia.
Evaluation of Matrix Metalloproteinase-2 (MMP-2) and -9 (MMP-9) and Their Tissue Inhibitors (TIMP-1 and TIMP-2) in Plasma from Patients with Neurodegenerative Dementia.
Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases.
Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity.
Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarction.
Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.
The role of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the pathophysiology of neurodegeneration: a literature study.
Dementia, Vascular
Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.
Demyelinating Diseases
Inhibition of autoimmune encephalomyelitis by a tetracycline.
Matrix metalloproteinase upregulation in chronic inflammatory demyelinating polyneuropathy and nonsystemic vasculitic neuropathy.
Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons.
Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barré syndrome.
MMP-12, MMP-3, and TIMP-1 are markedly upregulated in chronic demyelinating theiler murine encephalomyelitis.
Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis.
Dengue
Relationship between MMP Expression and Virulence of Dengue Virus Type-2 in Infected Mosquito and Mammalian Cells.
Severity of Plasma Leakage Is Associated With High Levels of Interferon ?-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
Dental Pulp Necrosis
Decreased levels of matrix metalloproteinase-2 in root-canal exudates during root canal treatment.
Dentigerous Cyst
Correlation between radiographic area and immunolocation of MMP-2 and MMP-9 in unilocular radiographic lesions.
Presence of myofibroblasts and matrix metalloproteinase 2 in radicular cysts, dentigerous cysts, and keratocystic odontogenic tumors: a comparative immunohistochemical study.
Dermatitis
Expression of matrix metalloproteinases (MMP-2, MMP-3, and MMP-9) and fibronectin in lichen planus.
Inflammation in stasis dermatitis upregulates MMP-1, MMP-2 and MMP-13 expression.
Dermatitis, Allergic Contact
Gelatinase expression at positive patch test reactions.
Dermatitis, Atopic
Increased Expression of Gelatinase and Caspase Activities in the Skin of NC/Tnd Mice: A Model for Atopic Dermatitis.
Dermatitis, Contact
Analysis of skin patch test results and metalloproteinase-2 levels in a patient with contact dermatitis.
Collagen of chronically inflamed skin is over-modified and upregulates secretion of matrix metalloproteinase 2 and matrix-degrading enzymes by endothelial cells and fibroblasts.
Dermatitis, Phototoxic
Protective effect of chromene isolated from Sargassum horneri against UV-A-induced damage in skin dermal fibroblasts.
Dermatofibrosarcoma
Expression of MMP-2, MMP-9 and MMP-11 in dermatofibroma and dermatofibrosarcoma protuberans.
Dermatomyositis
Expression of matrix metalloproteinases in the muscle of patients with inflammatory myopathies.
Diabetes Mellitus
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Anti-apoptotic activity of human matrix Metalloproteinase-2 attenuates diabetes mellitus.
Carotid thickness and atherosclerotic plaque stability, serum inflammation, serum MMP-2 and MMP-9 were associated with acute cerebral infarction.
Changes in Activity of Matrix Metalloproteinases and Serum Concentrations of Proinsulin and C-Peptide Depending on the Compensation Stage of Type 2 Diabetes Mellitus.
Circulating matrix metalloproteinase-2 is associated with cystatin C level, posttransplant duration, and diabetes mellitus in kidney transplant recipients.
Circulating matrix metalloproteinases and their endogenous inhibitors in patients with erectile dysfunction.
Effect of Non-Surgical Periodontal Therapy on CRP, Oxidative Stress, MMP-9 and MMP-2 Levels in Patients With Type 2 Diabetes. A Randomized Controlled Study.
Effects of N-acetylcysteine on kidney tissue, matrix metalloproteinase-2, irisin and oxidative stress in a diabetes mellitus model.
Effects of pioglitazone on expressions of matrix metalloproteinases 2 and 9 in kidneys of diabetic rats.
Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy.
Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus.
Genetic factors for lone atrial fibrillation.
Immunoreactivity of ICAM-1, MMP-2, and Nesfatin-1 in lens epithelial cells of patients with diabetes mellitus with or without diabetic retinopathy.
Increased circulatory MMP-2 and MMP-9 levels and activities in patients with type 1 diabetes mellitus.
Intraocular matrix metalloproteinase 2 and 9 in patients with diabetes mellitus with and without diabetic retinopathy.
Matrix metalloproteinase 2 may be a marker of microangiopathy in children and adolescents with type 1 diabetes mellitus.
Matrix Metalloproteinase Gene Polymorphisms and New-Onset Diabetes After Kidney Transplantation in Korean Renal Transplant Subjects.
MMP-2 gene polymorphisms in type 2 diabetes mellitus diabetic retinopathy.
MMP-2 salivary activity in type 2 diabetes mellitus patients.
MMP-2 serum concentrations predict mortality in hemodialysis patients: a 5-year cohort study.
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
Periodontal Condition and Immunological Aspects of Individuals Hospitalized in the Intensive Care Unit.
Plasma levels of MMP-2, MMP-9 and TIMP-1 are not associated with arterial stiffness in subjects with type 2 diabetes mellitus.
Potential role of increased matrix metalloproteinase-2 (MMP2) transcription in impaired adipogenesis in type 2 diabetes mellitus.
Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus.
Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus.
Serum cystatin C and tubular urinary enzymes as biomarkers of renal dysfunction in type 2 diabetes mellitus.
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
The expression of two isoforms of matrix metalloproteinase-2 in aged mouse models of diabetes mellitus and chronic kidney disease.
The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus.
The Protective Role of Autophagy in Matrix Metalloproteinase-Mediated Cell Transmigration and Cell Death in High-Glucose-Treated Endothelial Cells.
The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus.
Tissue inhibitor of metalloproteinase-2 inhibits T-cell infiltration and preserves pancreatic beta-cell function in an in vitro type 1 diabetes mellitus model.
[Change of expression of matrix metalloproteinase-2 in the periodontal tissues of diabetes mellitus rats during orthodontic tooth movement]
Diabetes Mellitus, Experimental
Enhanced cardiac expression of two isoforms of matrix metalloproteinase-2 in experimental diabetes mellitus.
Renal proteinases and kidney hypertrophy in experimental diabetes.
Diabetes Mellitus, Type 1
Erratum to: Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study.
Increased circulatory MMP-2 and MMP-9 levels and activities in patients with type 1 diabetes mellitus.
Kidney injury molecule-1 and neutrophil gelatinase associated lipocalin in normoalbuminuric diabetic children.
Matrix metalloproteinase -2, -9 and arterial stiffness in children and adolescents: The role of chronic kidney disease, diabetes, and hypertension.
Matrix metalloproteinase 2 may be a marker of microangiopathy in children and adolescents with type 1 diabetes mellitus.
Matrix metalloproteinase 2 may be a marker of microangiopathy in children and adolescents with type 1 diabetes.
Matrix metalloproteinase-2 dysregulation in type 1 diabetes.
Matrix metalloproteinases in subjects with type 1 diabetes.
Peripheral blood level alterations of TIMP-1, MMP-2 and MMP-9 in patients with type 1 diabetes.
Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study.
Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus.
The skin remodeling in type 1 diabetes and insulin resistance animal models.
Tissue inhibitor of metalloproteinase-2 inhibits T-cell infiltration and preserves pancreatic beta-cell function in an in vitro type 1 diabetes mellitus model.
[Metalloproteinases MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 levels in children and adolescents with type 1 diabetes.]
Diabetes Mellitus, Type 2
Association of matrix metalloproteinase-2 gene polymorphisms with susceptibility to type 2 diabetes: A case control study.
Changes in Activity of Matrix Metalloproteinases and Serum Concentrations of Proinsulin and C-Peptide Depending on the Compensation Stage of Type 2 Diabetes Mellitus.
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Down-regulation of glomerular matrix metalloproteinase-2 gene in human NIDDM.
Effect of Non-Surgical Periodontal Therapy on CRP, Oxidative Stress, MMP-9 and MMP-2 Levels in Patients With Type 2 Diabetes. A Randomized Controlled Study.
Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus.
Matrix Metalloproteinase Gene Polymorphisms and New-Onset Diabetes After Kidney Transplantation in Korean Renal Transplant Subjects.
Matrix metalloproteinase-2 (MMP-2) gene polymorphism and cardiovascular comorbidity in type 2 diabetes patients.
MMP-2 gene polymorphisms in type 2 diabetes mellitus diabetic retinopathy.
MMP-2 salivary activity in type 2 diabetes mellitus patients.
Nuclear factor-kappaB induction by visfatin in human vascular endothelial cells: its role in MMP-2/9 production and activation.
Plasma levels of MMP-2, MMP-9 and TIMP-1 are not associated with arterial stiffness in subjects with type 2 diabetes mellitus.
Potential role of increased matrix metalloproteinase-2 (MMP2) transcription in impaired adipogenesis in type 2 diabetes mellitus.
Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus.
Serum cystatin C and tubular urinary enzymes as biomarkers of renal dysfunction in type 2 diabetes mellitus.
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus.
The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus.
Diabetes, Gestational
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors in women with glucose intolerance in pregnancy and normal controls.
Diabetic Angiopathies
High glucose enhances MMP-2 production in adventitial fibroblasts via Akt1-dependent NF-kappaB pathway.
Production of type IV collagen and 72-kDa gelatinase by human endothelial cells cultured in high glucose. Effects of a protein kinase C inhibitor, GF 109203X.
[High glucose and tea polyphenols on expression of matrix metalloproteinase-2 and extracellular matrix metalloproteinase inducer in human umbilical vein endothelial cells]
Diabetic Cardiomyopathies
Antioxidant treatment protects diabetic rats from cardiac dysfunction by preserving contractile protein targets of oxidative stress.
Diabetic Cardiomiopathy Progression is Triggered by miR122-5p and Involves Extracellular Matrix: A 5-Year Prospective Study.
Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.
Role of TSPO/VDAC1 Upregulation and Matrix Metalloproteinase-2 Localization in the Dysfunctional Myocardium of Hyperglycaemic Rats.
The role of alpha-lipoic acid supplementation in the prevention of diabetes complications: A comprehensive review of clinical trials.
[Effects of tamoxifen on CD147 glycosylation and MMPs in the diabetic rat myocardium].
Diabetic Foot
Enzymatically active Peptostreptococcus magnus: association with site of infection.
Diabetic Nephropathies
An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy.
Association of serum sestrin 2 and betatrophin with serum neutrophil gelatinase associated lipocalin levels in type 2 diabetic patients with diabetic nephropathy.
C-peptide exhibits a late induction effect on matrix metallopeptidase-9 in high glucose-stimulated rat mesangial cells.
Changes of serum advanced glycation end products (AGEs), matrix metalloprotein-2 (MMP-2), and urinary microalbuminuria (mALB) in diabetic nephropathy and their predictive value for heart failure.
Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats.
Effects of pioglitazone on expressions of matrix metalloproteinases 2 and 9 in kidneys of diabetic rats.
Elevated matrix metalloproteinase-2 and -9 in urine, but not in serum, are markers of type 1 diabetic nephropathy.
Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy.
Epigenetic Regulation of the N-Terminal Truncated Isoform of Matrix Metalloproteinase-2 (NTT-MMP-2) and Its Presence in Renal and Cardiac Diseases.
Experimental diabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice.
In Diabetic Kidney Disease Urinary Exosomes Better Represent Kidney Specific Protein Alterations Than Whole Urine.
Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kappaB-dependent pathway.
Matrix metalloproteinase-2 (MMP-2) and membrane-type 1 MMP (MT1-MMP) affect the remodeling of glomerulosclerosis in diabetic OLETF rats.
Matrix metalloproteinase-2 and mesangiolysis in diabetic nephropathy.
Matrix metalloproteinase-2 dysregulation in type 1 diabetes.
Minocycline with aspirin: an approach to attenuate diabetic nephropathy in rats.
Pioglitazone Attenuates Cardiac Fibrosis and Hypertrophy in a Rat Model of Diabetic Nephropathy.
Plasma levels of tissue inhibitor of metalloproteinase-1 in patients with type 1 diabetes mellitus associate with early diabetic neuropathy and nephropathy.
PTGER3 and MMP-2 play potential roles in diabetic nephropathy via competing endogenous RNA mechanisms.
Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy.
Renal in situ hybridization studies of extracellular matrix related molecules in type 1 diabetes mellitus.
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Utility of urinary biomarkers as a diagnostic tool for early diabetic nephropathy in patients with type 2 diabetes mellitus.
[Effects of puerarin on renal function, expressions of MMP-2 and TIMP-2 in diabetic rats]
Diabetic Neuropathies
Matrix metalloproteinase-2 is downregulated in sciatic nerve by streptozotocin induced diabetes and/or treatment with minocycline: Implications for nerve regeneration.
Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy.
Diabetic Retinopathy
Attenuation of diabetic retinopathy by enhanced inhibition of MMP-2 and MMP-9 using aspirin and minocycline in streptozotocin-diabetic rats.
Circ-ITCH restrains the expression of MMP-2, MMP-9 and TNF-? in diabetic retinopathy by inhibiting miR-22.
Functional links between gelatinase B/matrix metalloproteinase-9 and prominin-1/CD133 in diabetic retinal vasculopathy and neuropathy.
Genetic variations and plasma levels of gelatinase A (matrix metalloproteinase-2) and gelatinase B (matrix metalloproteinase-9) in proliferative diabetic retinopathy.
Immunoreactivity of ICAM-1, MMP-2, and Nesfatin-1 in lens epithelial cells of patients with diabetes mellitus with or without diabetic retinopathy.
Interrelationship between activation of matrix metalloproteinases and mitochondrial dysfunction in the development of diabetic retinopathy.
Intraocular matrix metalloproteinase 2 and 9 in patients with diabetes mellitus with and without diabetic retinopathy.
Matrix metalloproteinase-2 expression and apoptogenic activity in retinal pericytes: implications in diabetic retinopathy.
Matrix metalloproteinase-2 in the development of diabetic retinopathy and mitochondrial dysfunction.
Matrix metalloproteinases in diabetic retinopathy: potential role of MMP-9.
MMP-2 gene polymorphisms in type 2 diabetes mellitus diabetic retinopathy.
Novel Role of Mitochondrial Matrix Metalloproteinase-2 in the Development of Diabetic Retinopathy.
Oxidative stress and the development of diabetic retinopathy: contributory role of matrix metalloproteinase-2.
Production and activation of matrix metalloproteinase-2 in proliferative diabetic retinopathy.
Regulation of Matrix Metalloproteinase in the Pathogenesis of Diabetic Retinopathy.
Role of matrix metalloproteinase-2 and -9 in the development of diabetic retinopathy.
VEGF Secreted by Hypoxic Muller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy.
Distemper
Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis.
Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis.
Diverticular Diseases
Increased concentration of tissue-degrading matrix metalloproteinases and their inhibitor in complicated diverticular disease.
Diverticulitis
Comparative analysis of the expression of metalloproteases and their inhibitors in resected crohn's disease and complicated diverticular disease.
Diverticulum
Up-regulation of collagen and tissue inhibitors of matrix metalloproteinase in colonic diverticular disease.
Down Syndrome
Analysis of matrix metalloproteinase (MMP-8 and MMP-2) activity in gingival crevicular fluid from children with Down's syndrome.
Enhancement of matrix metalloproteinase (MMP)-2 activity in gingival tissue and cultured fibroblasts from Down's syndrome patients.
Dry Eye Syndromes
High Levels of 17?-Estradiol Are Associated with Increased Matrix Metalloproteinase-2 and Metalloproteinase-9 Activity in Tears of Postmenopausal Women with Dry Eye.
Duodenal Ulcer
Inappropriate Angiogenic Response as a Novel Mechanism of Duodenal Ulceration and Impaired Healing.
[Role of Allelic Genes of Matrix Metalloproteinases and Their Tissue Inhibitors in the Peptic Ulcer Disease Development].
Dupuytren Contracture
Expression of MMP-2, TIMP-2, TGF-?1, and Decorin in Dupuytren's Contracture.
Gelatinase A activity in Dupuytren's disease.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in sera and tissue of patients with Dupuytren's disease.
MMP-14 and MMP-2 are key metalloproteases in Dupuytren's disease fibroblast-mediated contraction.
Dwarfism
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Dyslipidemias
Evaluation of metalloproteinase 2 and 9 levels and their inhibitors in combined dyslipidemia.
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
The effect of obesity and tobacco smoke exposure on inflammatory mediators and matrix metalloproteinases in rat model.
Dysplastic Nevus Syndrome
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Matrix metalloproteinases MMP-1, MMP-2, and MMP-13 are overexpressed in primary nodular melanoma.
Dyspnea
Matrix metalloproteinases and tissue remodeling in hypertrophic cardiomyopathy.
Ear Neoplasms
[Expression of matrix metalloproteinasa-2,9 in cholesteatoma and middle ear cancer]
Embolic Stroke
Matrix metalloproteinase expression after human cardioembolic stroke: temporal profile and relation to neurological impairment.
Matrix metalloproteinase expression is related to hemorrhagic transformation after cardioembolic stroke.
MMP-2 concentrations in stroke according to etiology: Adjusting for enzyme degradation in stored deep-frozen serum and other methodological pitfalls.
Embolism
Cyclophosphamide promotes pulmonary metastasis on mouse lung adenocarcinoma.
Empyema
Matrix metalloproteinase levels in the differentiation of parapneumonic pleural effusions.
Encephalitis
Circulating levels of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases during Japanese encephalitis virus infection.
Increased matrix metalloproteinases in cerebrospinal fluids of patients with major depressive disorder and schizophrenia.
Matrix metalloproteinase-2 and -9 lead to fibronectin degradation in astroglia infected with Toxoplasma gondii.
Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis.
Encephalitis, Viral
Expression of MMP-2 and TIMP-1 in cerebrospinal fluid and the correlation with dynamic changes of serum PCT in neonatal purulent meningitis.
Encephalomyelitis
Distinct roles for matrix metalloproteinase-2 and alpha4 integrin in autoimmune T cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis.
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.
Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.
Magnetic brain stimulation upregulates adhesion and prevents Eae: MMP-2, ICAM-1, and VCAM-1 in the choroid plexus as a target.
Minocycline suppresses experimental autoimmune encephalomyelitis by increasing tissue inhibitors of metalloproteinases.
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
MMP-2, VCAM-1 and NCAM-1 expression in the brain of rats with experimental autoimmune encephalomyelitis as a trigger mechanism for synaptic plasticity and pathology.
On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation.
Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis.
Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2.
Encephalomyelitis, Autoimmune, Experimental
Distinct roles for matrix metalloproteinase-2 and alpha4 integrin in autoimmune T cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis.
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.
Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.
Magnetic brain stimulation upregulates adhesion and prevents Eae: MMP-2, ICAM-1, and VCAM-1 in the choroid plexus as a target.
Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis.
Minocycline suppresses experimental autoimmune encephalomyelitis by increasing tissue inhibitors of metalloproteinases.
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
MMP-2, VCAM-1 and NCAM-1 expression in the brain of rats with experimental autoimmune encephalomyelitis as a trigger mechanism for synaptic plasticity and pathology.
Pathological findings in rats with experimental allergic encephalomyelitis.
Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis.
Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2.
Endocarditis
Characterization of Enterococcus faecium isolates and first report of vanB phenotype-vanA genotype incongruence in the Middle East.
Comparison of the incidence of virulence determinants and antibiotic resistance between Enterococcus faecium strains of dairy, animal and clinical origin.
Enterocin AS-48RJ: a variant of enterocin AS-48 chromosomally encoded by Enterococcus faecium RJ16 isolated from food.
Enterococcal virulence determinants may be involved in resistance to clinical therapy.
Evaluation of Enterococcus mundtii ST4SA and Lactobacillus plantarum 423 as probiotics by using a gastro-intestinal model with infant milk formulations as substrate.
Fsr-independent production of protease(s) may explain the lack of attenuation of an Enterococcus faecalis fsr mutant versus a gelE-sprE mutant in induction of endocarditis.
Gelatinase contributes to the pathogenesis of endocarditis caused by Enterococcus faecalis.
Gelatinase is important for translocation of Enterococcus faecalis across polarized human enterocyte-like T84 cells.
Genotypic and phenotypic diversity in Enterococcus faecalis: is agar invasion a pathogenicity score?
Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons.
Incidence of virulence factors in enterococci from raw and fermented meat and biofilm forming capacity at 25°C and 37°C.
IS256 abolishes gelatinase activity and biofilm formation in a mutant of the nosocomial pathogen Enterococcus faecalis V583.
Prevalence of enterococcus species and their virulence genes in fresh water prior to and after storm events.
Safety of Lactobacillus plantarum ST8Sh and Its Bacteriocin.
Survey for virulence determinants among Enterococcus faecalis isolated from different sources.
The Enterococcus faecalis fsr two-component system controls biofilm development through production of gelatinase.
Virulence and antimicrobial resistance in clinical Enterococcus faecium.
Virulence, phenotype and genotype characteristics of endodontic Enterococcus spp.
[The study of activity of matrix metalloproteinases abd reactants of inflammation in patients with endocarditis.]
Endoleak
Correlation of Baseline Plasma and Inguinal Connective Tissue Metalloproteinases and Their Inhibitors With Late High-Pressure Endoleak After Endovascular Aneurysm Repair: Long-term Results.
Endometrial Hyperplasia
Enhanced expressions of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factors (VEGF) and increased microvascular density in the endometrial hyperplasia of women with anovulatory dysfunctional uterine bleeding.
Matrix metalloproteinases (MMPs) in the endometrium of bitches.
Matrix Metalloproteinases and Their Tissue Inhibitors in Blood Serum of Patients with Endometrial Cancer: Clinical and Morphological Correlations.
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells.
Endometrial Neoplasms
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with upgrading and myometrial invasion in endometrial carcinoma.
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Combination of strong MMP-2 and weak TIMP-2 immunostainings is a significant prognostic factor in endometrial carcinoma.
Corticotropin-releasing hormone enhances the invasiveness and migration of Ishikawa cells, possibly by increasing matrix metalloproteinase-2 and matrix metalloproteinase-9.
Detection of endometrial cancer by determination of matrix metalloproteinases in the uterine cavity.
Different pattern of zymography between human gynecologic normal and malignant tissues.
Differential expression of MMP-2, MMP-9 and PCNA in endometriosis and endometrial carcinoma.
Effects of curcumin on the role of MMP-2 in endometrial cancer cell proliferation and invasion.
Effects of hepatocyte growth factor on the expression of matrix metalloproteinases and their tissue inhibitors during the endometrial cancer invasion in a three-dimensional coculture.
ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer.
Expression of gelatinase (MMP-2 and MMP-9) and cyclooxygenase-2 (COX-2) in endometrial carcinoma.
Expression of matrix metalloproteinase-2 and survivin in endometrioid and nonendometrioid endometrial cancers and clinicopathologic significance.
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in uterine endometrial carcinoma and a correlation between expression of matrix metalloproteinase-7 and prognosis.
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
Gelatinases A and B (MMP-2 and MMP-9) in endometrial cancer-MMP-9 correlates to the grade and the stage.
IL-37b?1-45 suppresses the migration and invasion of endometrial cancer cells by targeting the Rac1/NF-?B/MMP2 signal pathway.
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage I and II endometrial cancer.
Immunohistochemical expression of hormone receptors, Ki-67, endoglin (CD105), claudins 3 and 4, MMP-2 and -9 in endometrial polyps and endometrial cancer type I.
Immunohistochemical expression of MMP-2, MMP-9 and COX-2 in Stage IA malignant polyps of the endometrium.
Inhibitory effect of ginsenoside-Rb2 on invasiveness of uterine endometrial cancer cells to the basement membrane.
Malignant cell-specific gelatinase activity in human endometrial carcinoma.
Matrix metalloproteinase-7 (MMP-7) polymorphism is a risk factor for endometrial cancer susceptibility.
Matrix Metalloproteinases and Their Tissue Inhibitors in Blood Serum of Patients with Endometrial Cancer: Clinical and Morphological Correlations.
Metalloproteinase-2, -7 and -9 and tissue inhibitor of metalloproteinase-1 and -2 expression in normal, hyperplastic and neoplastic endometrium: a clinical-pathological correlation study.
miR-124 functions as a tumor suppressor in the endometrial carcinoma cell line HEC-1B partly by suppressing STAT3.
MMP-2 expression associates with CA 125 and clinical course in endometrial carcinoma.
Overexpression of BP1, an isoform of Homeobox Gene DLX4, promotes cell proliferation, migration and predicts poor prognosis in endometrial cancer.
p21-activated kinase 4 regulation of endometrial cancer cell migration and invasion involves the ERK1/2 pathway mediated MMP-2 secretion.
Papers to appear in forthcoming issues
Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion.
Role of emmprin in endometrial cancer.
Selective gene transfer to endometrial cancer cells by a polymer against matrix metalloproteinase 2 (MMP-2).
The association of transforming growth factor-beta 1 with myometrial invasion of endometrial carcinomas through effects on matrix metalloproteinase.
The influence of vascular endothelial growth factor-A and matrix metalloproteinase-2 and -9 in angiogenesis, metastasis, and prognosis of endometrial cancer.
The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid receptors expression in endometrial cancer.
[Activity of matrix metalloproteinases -2 and -9 (MMP-2 and MMP-9) and content of their tissue inhibitors in endometrial cancer--a preliminary study]
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
[Matrix metalloproteinases and their tissue inhibitors in malignancies of the female genital tract]
[Methylation of matrix metalloproteinases-2 promoter in endometrial cancer invasion].
[Progesterone receptor's profile and the effect of the hormone and its derivatives on invasiveness and MMP2 secretion in endometrial carcinoma cell lines]
[Prognostic value of serum MMP-2 level in uterine cancer affected women]
Endometriosis
15-Epi-lipoxin A(4) inhibits the progression of endometriosis in a murine model.
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 agree with progression of ovarian endometriomas.
Association between matrix metalloproteinase-2 and matrix metalloproteinase-9 polymorphisms and endometriosis: A systematic review and meta-analysis.
Association Between MMP-2 and TIMP-2 Gene Polymorphisms and Advanced-Stage Endometriosis in Korean Women.
Association of polymorphisms of the MMP-2 and TIMP-2 genes with the risk of endometriosis in North Chinese women.
Associations between various possible promoter polymorphisms of MMPs genes and endometriosis risk: a meta-analysis.
Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling.
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity.
Change profiles in matrix metalloproteinase-2 and -9 in induced endometriosis in mice.
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Curcumin delays endometriosis development by inhibiting MMP-2 activity.
Differential expression of MMP-2, MMP-9 and PCNA in endometriosis and endometrial carcinoma.
Differential regulation of matrix metalloproteinase-3 gene expression in endometriotic lesions compared with endometrium.
Disturbed progesterone signalling in an advanced preclinical model of endometriosis.
Doxycycline reduces MMP-2 activity and inhibits invasion of 12Z epithelial endometriotic cells as well as MMP-2 and -9 activity in primary endometriotic stromal cells in vitro.
Effect of matrix metalloproteinase promoter polymorphisms on endometriosis and adenomyosis risk: evidence from a meta-analysis.
Effect of traditional Chinese medicine (Xiaochaihu Tang) on the expression of MMP-2 and MMP-9 in rats with endometriosis.
Effects of estrogen and progestin on expression of MMP-2 and TIMP-2 in a nude mouse model of endometriosis.
Effects of Yiweining recipe on expressions of metalloproteinase-2 and cyclooxygenase-2 mRNAs in ectopic endometrium of rats with endometriosis.
Endometriotic epithelial cells induce MMPs expression in endometrial stromal cells via an NFkappaB-dependent pathway.
Eutopic endometrium and peritoneal, ovarian and bowel endometriotic tissues express a different profile of matrix metalloproteinases-2, -3 and -11, and of tissue inhibitor metalloproteinases-1 and -2.
Evidence for an increased release of proteolytic activity by the eutopic endometrial tissue in women with endometriosis and for involvement of matrix metalloproteinase-9.
Expression and significance of autophagy genes LC3, Beclin1 and MMP-2 in endometriosis.
Expression and Significance of Matrix Metalloproteinase-2 and Matrix Metalloproteinas-9 in Endometriosis.
Expression of CD44s, vascular endothelial growth factor, matrix metalloproteinase-2 and Ki-67 in peritoneal, rectovaginal and ovarian endometriosis.
Expression of metalloproteinase-9 in ectopic endometrium in women with endometriosis.
Gelatinase A (MM-2), gelatinase B (MMP-9) and their inhibitors (TIMP 1, TIMP-2) in serum of women with endometriosis: Significant correlation between MMP-2, MMP-9 and their inhibitors without difference in levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in relation to the severity of endometriosis.
Gene expression of adhesion molecules and matrix metalloproteinases in endometriosis.
Genetic polymorphisms and endometriosis: contribution of genes that regulate vascular function and tissue remodeling.
Human Wharton's jelly stem cells inhibit endometriosis through apoptosis induction.
Increased Circulating MMP-2 Levels in Infertile Patients With Moderate and Severe Pelvic Endometriosis.
Investigating the association of matrix metalloproteinase-2 gene variants with endometriosis in an Iranian population.
Matrix metalloproteinase 2 is associated with changes in steroid hormones in the sera and peritoneal fluid of patients with endometriosis.
Matrix metalloproteinase messenger RNA expression in human endometriosis grafts cultured on a chicken chorioallantoic membrane.
Matrix metalloproteinase-2 (MMP-2), MMP-9, tissue inhibitor of matrix metalloproteinases (TIMP-1) and transforming growth factor-?2 (TGF-?2) expression in eutopic endometrium of women with peritoneal endometriosis.
Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium.
Matrix metalloproteinases 2 and 9, E-cadherin, and beta-catenin expression in endometriosis, low-grade endometrial carcinoma and non-neoplastic eutopic endometrium.
Matrix metalloproteinases are elevated in the urine of patients with endometriosis.
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells.
Mechanisms regulating invasiveness and growth of endometriosis lesions in rat experimental model and in humans.
mRNA expression and DNA methylation level of the MMP-2 gene in peritoneal endometriosis.
Polymorphisms in MMP-2 and MMP-9 promoter regions are associated with endometriosis.
Regulation of Matrix Metalloproteinase-2 Activity by COX-2-PGE2-pAKT Axis Promotes Angiogenesis in Endometriosis.
SMURF1-mediated ubiquitylation of SHP-1 promotes cell proliferation and invasion of endometrial stromal cells in endometriosis.
Suppression of matrix metalloproteinase-9 by prostaglandin E(2) in peritoneal macrophage is associated with severity of endometriosis.
Survivin, MMP-2, MT1-MMP, and TIMP-2: their impact on survival, implantation, and proliferation of endometriotic tissues.
The Effect of Imbalanced Progesterone Receptor-A/-B Ratio on Gelatinase Expressions in Endometriosis.
The modulating effects of Resveratrol on the expression of MMP-2 and MMP-9 in endometriosis women: a randomized exploratory trial.
TNFRp55 deficiency promotes the development of ectopic endometriotic-like lesions in mice.
Ureaplasma Urealyticum Infection Contributes to the Development of Pelvic Endometriosis Through Toll-Like Receptor 2.
Vascular endothelial growth factor and matrix metalloproteinase-2 expedite formation of endometriosis in the early stage ICR mouse model.
[Effect of progesterone on the secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 in human ectopic endometrial stromal cells]
[Effect of the combination of bushen xuguan recipe and ruanjian huayu recipe on the MMP-2 expression in endometriosis rats].
[Effects of acupuncture combined with medicine on expression of matrix metalloproteinase-2 in the rat of endometriosis]
[Expression of matrix metalloproteinase and tissue inhibitor of metalloproteinase in adenomyosis]
[Inhibitory effect on estrogen production and its influence on invasive ability of human endometrial cells of endometriosis by medicated serum of SLW]
[Molecular biological features of ectopic and eutopic endometrium in genital endometriosis].
[Study on the association of SNPs of MMP-2 and TIMP-2 genes with the risk of endometriosis and adenomyosis]
Endophthalmitis
Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis.
Endotoxemia
ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels.
Endotoxemia shifts neutrophils with TIMP-free gelatinase B/ MMP-9 from bone marrow to periphery and induces systematic upregulation of TIMP-1.
Matrix metalloproteinase activities are altered in the heart and plasma during endotoxemia.
Rat gastric gelatinase induction during endotoxemia.
Roles of MMP-2/-9 in cardiac dysfunction during early multiple organ failure in an ovine animal model.
Small interfering RNA targeting focal adhesion kinase prevents cardiac dysfunction in endotoxemia.
Enteritis
Role of matrix metalloproteinases in the pathogenesis of childhood gastroenteritis.
Ependymoma
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
Epidermal Cyst
Gelatinase B in chronic synovitis: immunolocalization with a monoclonal antibody.
Epidermolysis Bullosa Dystrophica
Inhibition of collagen degradative enzymes by retinoic acid in vitro.
Skin expression of metalloproteinases and tissue inhibitor of metalloproteinases in sibling patients with recessive dystrophic epidermolysis and intrafamilial phenotypic variation.
Epidermolysis Bullosa Simplex
Epidermolysis bullosa simplex: expression of gelatinase activity in cultured human skin fibroblasts.
Gelatinase expression in generalized epidermolysis bullosa simplex fibroblasts.
Epilepsy
Chronic Intermittent Ethanol Exposure Induces Upregulation of Matrix Metalloproteinase-9 in the Rat Medial Prefrontal Cortex and Hippocampus.
Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors.
Gelatinase Biosensor Reports Cellular Remodeling During Epileptogenesis.
Imbalance of matrix metalloproteinase-9 and matrix metalloproteinase tissue inhibitor-1 may contribute to hemorrhage in cerebellar arteriovenous malformations.
Increased Expression of Matrix Metalloproteinase-9 in Patients with Temporal Lobe Epilepsy.
Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura.
Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy.
Matrix metalloproteinases contribute to neuronal dysfunction in animal models of drug dependence, Alzheimer's disease, and epilepsy.
Recruited leukocytes and local synthesis account for increased matrix metalloproteinase-9 activity in cerebrospinal fluid of dogs with central nervous system neoplasm.
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Serum matrix metalloproteinase-2: A potential biomarker for diagnosis of epilepsy.
Epilepsy, Temporal Lobe
Gelatinase Biosensor Reports Cellular Remodeling During Epileptogenesis.
Increased Expression of Matrix Metalloproteinase-9 in Patients with Temporal Lobe Epilepsy.
Epiretinal Membrane
Interleukin-1-beta changes the expression of metalloproteinases in the vitreous humor and induces membrane formation in eyes containing preexisting retinal holes.
Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.
Vitreous TIMP-1 levels associate with neovascularization and TGF-?2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy.
Erythema
A synthetic peptide blocking TRPV1 activation inhibits UV-induced skin responses.
Protective effects of green tea extracts on photoaging and photommunosuppression.
Erythema Nodosum
Matrix metalloproteinase-2, -9, -12, and tissue inhibitor of metalloproteinase 2 gene polymorphisms and cutaneous expressions in patients with Behçet's disease.
Escherichia coli Infections
Activation of human progelatinase A/promatrix metalloproteinase 2 by Escherichia coli-derived serine proteinase.
Esophageal Achalasia
Gelatinase B/Matrix Metalloproteinase-9 as Innate Immune Effector Molecule in Achalasia.
Esophageal Neoplasms
A Novel Role of Cab45-G in Mediating Cell Migration in Cancer Cells.
Androgen receptor promotes esophageal cancer cell migration and proliferation via matrix metalloproteinase 2.
Expression of decorin in esophageal cancer in relation to the expression of three isoforms of transforming growth factor-beta (TGF-beta1, -beta2, and -beta3) and matrix metalloproteinase-2 activity.
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Matrix metalloproteinase 2 and 9 in esophageal cancer.
MiR-196a binding-site SNP regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis.
MMP-2 and DcR3 expression in esophageal cancer tissue and correlation with patient survival.
Prognostic significance of stromelysin-3 and tissue inhibitor of matrix metalloproteinase-2 in esophageal cancer.
Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
[Genetic polymorphisms in STK15 and MMP-2 associated susceptibility to esophageal cancer in Mongolian population]
Esophageal Squamous Cell Carcinoma
ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Aurora-A modulates MMP-2 expression via AKT/NF-?B pathway in esophageal squamous cell carcinoma cells.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
CD147 and matrix metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma.
Differential expression of MMP and uPA systems and prognostic relevance of their expression in esophageal squamous cell carcinoma.
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
miR-29b inhibits the progression of esophageal squamous cell carcinoma by targeting MMP-2.
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells.
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Phenotypes of human esophageal squamous cell carcinoma based on matrix metalloproteinase production.
Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus.
S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity.
Substance P accelerates the progression of human esophageal squamous cell carcinoma via MMP-2, MMP-9, VEGF-A, and VEGFR1 overexpression.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma.
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
[Expression of S100A4 in esophageal squamous cell carcinoma and its relation to tumor invasion and metastasis]
Essential Hypertension
Correlations of MMP-1 and MMP-2 gene polymorphisms with essential hypertension.
Elevated Levels of MMP-9 in Untreated Patients with Stage I Essential Hypertension.
MMP-2 and sTNF-R1 Variability in Patients with Essential Hypertension: 1-Year Follow-Up Study.
Plasma levels of active extracellular matrix metalloproteinases 2 and 9 in patients with essential hypertension before and after antihypertensive treatment.
The effect of Ca2+ channel antagonists on plasma concentrations of matrix metalloproteinase-2 and -9 in essential hypertension.
Exfoliation Syndrome
Matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2, and transforming growth factor beta 1 in the aqueous humor and serum of patients with pseudoexfoliation syndrome.
Eye Diseases
Induction of matrix metalloproteinases 2 and 9 following stress to the lens.
Eye Infections
(-)Epigallocatechin-3-gallate inhibits gelatinase activity of some bacterial isolates from ocular infection, and limits their invasion through gelatine.
Factor XIII Deficiency
Association between expression of MMP-2 and MMP-9 genes and pathogenesis of intracranial hemorrhage in severe coagulation factor XIII deficiency.
Expression and CpG island methylation pattern of MMP-2 and MMP-9 genes in patients with congenital factor XIII deficiency and intracranial hemorrhage.
Fanconi Anemia
Cytokines, inducers and inhibitors modulate MMP-2 and MMP?9 secretion by human Fanconi anemia immortalized fibroblasts.
IL-6, IL-8, MMP-2, MMP-9 are overexpressed in Fanconi anemia cells through a NF-?B/TNF-? dependent mechanism.
Fatty Liver
Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet.
Higher hepatic gene expression and serum levels of matrix metalloproteinase-2 are associated with steatohepatitis in non-alcoholic fatty liver diseases.
Sesame oil attenuates nutritional fibrosing steatohepatitis by modulating matrix metalloproteinases-2, 9 and PPAR-?.
Fetal Growth Retardation
Midregional pro-adrenomedullin and matrix metalloproteinase-2 levels in intrauterine growth restriction and small gestational age pregnancies: biochemical diagnostic difference.
Fetal Membranes, Premature Rupture
Expression of a progelatinase activator (MT1-MMP) in human fetal membranes.
Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes.
Fibroadenoma
72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization.
Augmented release of matrix metalloproteinase-9 by PKC activation in organotypic cultures of human breast cancer and adjacent normal breast tissue and fibroadenoma.
Expression of activated gelatinase in human invasive breast carcinoma.
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Expression of matrix metalloproteinase 2 and 9 in breast cancer and breast fibroadenoma: a randomized, double-blind study.
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Immunolocalization of matrix metallo-proteinases and their tissue inhibitor in human mammary pathology.
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.
Fibrocystic Breast Disease
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Fibroma
Local activity of matrix metalloproteinases in a case of botryoid sarcoma.
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues.
Fibromatosis, Aggressive
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Fibromatosis, Gingival
Alteration in expression of MMP-1 and MMP-2 but not TIMP-1 and TIMP-2 in hereditary gingival fibromatosis is mediated by TGF-beta 1 autocrine stimulation.
Effect of transforming growth factor-beta1, interleukin-6, and interferon-gamma on the expression of type I collagen, heat shock protein 47, matrix metalloproteinase (MMP)-1 and MMP-2 by fibroblasts from normal gingiva and hereditary gingival fibromatosis.
Fibrosarcoma
(-)Epigallocatechin-3-gallate directly inhibits MT1-MMP activity, leading to accumulation of nonactivated MMP-2 at the cell surface.
3,5-Dicaffeoyl-epi-quinic acid inhibits the PMA-stimulated activation and expression of MMP-9 but not MMP-2 via downregulation of MAPK pathway.
A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness.
A specific sequence of the noncollagenous domain of the alpha3(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells.
Anticancer Efficacy of Polyphenols and Their Combinations.
Antisense Deoxyoligonucleotides Inhibit Activities of Matrix Metalloproteinase-2 in Human Fibrosarcoma HT1080 Cells.
Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase.
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).
Biosynthesis and recovery of selenium nanoparticles and the effects on matrix metalloproteinase-2 expression.
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).
Carbohydrate-mediated regulation of matrix metalloproteinase-2 activation in normal human fibroblasts and fibrosarcoma cells.
CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1- MMP/MMP-2 activity--role of GPS autoproteolysis and functional cooperation between the N- and C-terminal fragments.
Cellular cholesterol regulates MT1 MMP dependent activation of MMP 2 via MEK-1 in HT1080 fibrosarcoma cells.
Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2.
Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties.
Chemoprevention by pyrimethamine.
Chemopreventive effect of M2000, a new anti-inflammatory agent.
Collagen-binding domains of gelatinase A and thrombospondin-derived peptides impede endocytic clearance of active gelatinase A and promote HT1080 fibrosarcoma cell invasion.
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.
Constituents of Aquilaria sinensis Leaves Upregulate the Expression of Matrix Metalloproteases 2 and 9.
Culture of human fibrosarcoma HT-1080 cells in presence of fibronectin activates MMP-2.
Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA.
Dieckol from Ecklonia cava Regulates Invasion of Human Fibrosarcoma Cells and Modulates MMP-2 and MMP-9 Expression via NF-?B Pathway.
Differential effects of trichostatin A on gelatinase A expression in 3T3 fibroblasts and HT-1080 fibrosarcoma cells: implications for use of TSA in cancer therapy.
Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells.
DTD, an anti-inflammatory ditriazine, inhibits angiogenesis in vitro and in vivo.
Effect of piroxicam on matrix metalloproteinase 2 and apoptosis.
Eicosapentaenoic acid reduces the invasive and metastatic activities of malignant tumor cells.
Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells.
Evaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment.
Evaluation of MMP Inhibitors Isolated from Ligustrum japonicum Fructus.
Ginsenoside 20(S)-protopanaxadiol inhibits the proliferation and invasion of human fibrosarcoma HT1080 cells.
Heat shock suppresses membrane type 1-matrix metalloproteinase production and progelatinase A activation in human fibrosarcoma HT-1080 cells and thereby inhibits cellular invasion.
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Highly activated matrix metalloproteinase-2 secreted from clones of metastatic lung nodules of nude mice injected with human fibrosarcoma HT1080.
Human fibronectin and MMP-2 collagen binding domains compete for collagen binding sites and modify cellular activation of MMP-2.
Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity.
Hydrophilic extract from Posidonia oceanica inhibits activity and expression of gelatinases and prevents HT1080 human fibrosarcoma cell line invasion.
Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells.
Identification of matrix metalloproteinase inhibitors by chemical arrays.
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline, arginine, and green tea extract on human fibrosarcoma cells HT-1080.
Inhibition of human collagenase activity by antisense oligonucleoside methylphosphonates.
Inhibition of matrix metalloproteinase activity and growth of gastric adenocarcinoma cells by an angiotensin converting enzyme inhibitor in in vitro and murine models.
Inhibition of MMP-2 and MMP-9 Activities by Limonium tetragonum Extract.
Inhibition of the expression on MMP-2, 9 and morphological changes via human fibrosarcoma cell line by 6,6'-bieckol from marine alga Ecklonia cava.
Inhibitory effect of obovatal on the migration and invasion of HT1080 cells via the inhibition of MMP-2.
Inhibitory effect of the carnosine-gallic acid synthetic peptide on MMP-2 and MMP-9 in human fibrosarcoma HT1080 cells.
Inhibitory effects of a benz[f]indole-4,9-dione analog on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
Inhibitory effects of caffeic acid phenethyl ester on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells.
Matrix metalloproteinase 2 in tumor cell-induced platelet aggregation: regulation by nitric oxide.
Matrix metalloproteinase 2 secretion in WEHI 164 fibrosarcoma cells is nitric oxide-related and modified by morphine.
Matrix metalloproteinase-2 and -9 involvement in canine tumors.
MicroRNA-29 Family Suppresses the Invasion of HT1080 Human Fibrosarcoma Cells by Regulating Matrix Metalloproteinase 2 Expression.
Modulation of type IV collagenase and plasminogen activator in a hamster fibrosarcoma by basement membrane components and lung fibroblasts.
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Mosaic structure of the secreted ECM metalloproteases and interaction of the type IV collagenases with inhibitors.
Near-infrared triple-helical peptide with quenched fluorophores for optical imaging of MMP-2 and MMP-9 proteolytic activity in vivo.
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2).
Novel processing of beta-amyloid precursor protein catalyzed by membrane type 1 matrix metalloproteinase releases a fragment lacking the inhibitor domain against gelatinase A.
Particle irradiation suppresses metastatic potential of cancer cells.
Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface.
Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
Rapid trafficking of membrane type 1-matrix metalloproteinase to the cell surface regulates progelatinase a activation.
RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata.
Regulated Expressions of MMP-2, -9 by Diterpenoids from Euphorbia formosana Hayata.
Regulation of matrix metalloproteinase-2 (gelatinase A, MMP-2), membrane-type matrix metalloproteinase-1 (MT1-MMP) and tissue inhibitor of metalloproteinases-2 (TIMP-2) expression by elastin-derived peptides in human HT-1080 fibrosarcoma cell line.
Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate.
Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells.
Repression of stromelysin metalloprotease expression in rat fibrosarcoma cells by dimethylsulfoxide.
Retinoic acid synergizes with cyclic AMP to enhance MMP-2 basal promoter activity.
Salinomycin causes migration and invasion of human fibrosarcoma cells by inducing MMP-2 expression via PI3-kinase, ERK-1/2 and p38 kinase pathways.
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells.
The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form.
The C-terminal domain of tissue inhibitor of metalloproteinases-2 is required for cell binding but not for antimetalloproteinase activity.
The inhibitory mechanism of a novel cationic glucosamine derivative against MMP-2 and MMP-9 expressions.
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries.
Type IV collagen induces matrix metalloproteinase 2 activation in HT1080 fibrosarcoma cells.
Type IV collagenase activity of a primary HSV-2-induced hamster fibrosarcoma and its in vivo metastases and in vitro clones.
Wdnm1-like, a new adipokine with a role in MMP-2 activation.
Fluorosis, Dental
[Effect of fluoride on the expression of MMP-20/TIMP-2 in ameloblast of rat incisor and the antagonistic effect of melatonin against fluorosis].
Follicular Cyst
Involvement of Matrix Metalloproteinases and their Inhibitors in Bovine Cystic Ovarian Disease.
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Matrix metalloproteinases-2 and -9 activities in bovine follicular fluid of different-sized follicles: relationship to intra-follicular inhibin and steroid concentrations.
Foot Ulcer
Expression of miR-217 and HIF-1?/VEGF pathway in patients with diabetic foot ulcer and its effect on angiogenesis of diabetic foot ulcer rats.
Increased ratio of serum matrix metalloproteinase-9 against TIMP-1 predicts poor wound healing in diabetic foot ulcers.
Frontotemporal Dementia
MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations.
Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia.
Gallbladder Neoplasms
Guggulsterone enhances antitumor activity of gemcitabine in gallbladder cancer cells through suppression of NF-?B.
Gastrinoma
[Role of matrix metalloproteinase-2 and components of the extracellular matrix--collagen type IV and laminin expression in detection of the invasive potential of pancreatic tumors]
Gastritis
Enhanced systemic matrix metalloproteinase response in Helicobacter pylori gastritis.
Gastric gelatinase B/matrix metalloproteinase-9 is rapidly increased in Helicobacter felis-induced gastritis.
Gastrointestinal Neoplasms
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Gastrointestinal Stromal Tumors
[Correlation between expressions of matrix metalloproteinase-2 & 9 and vasculogenic mimicry in gastrointestinal stromal tumors]
gelatinase a deficiency
Angiotensin Type 1 Receptor Blocker Reduces Intimal Neovascularization and Plaque Growth in Apolipoprotein E-Deficient Mice.
Clinical and radiographic findings in two brothers affected with a novel mutation in matrix metalloproteinase 2 gene.
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Deficiency in matrix metalloproteinase-2 results in long-term vascular instability and regression in the injured mouse spinal cord.
Differential Actions of the Endocytic Collagen Receptor uPARAP/Endo180 and the Collagenase MMP-2 in Bone Homeostasis.
Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice.
Emergence of a metalloproteinase / phospholipase A2 axis of systemic inflammation.
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.
Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression.
Matrix Metalloproteinase-2 (MMP-2) Gene Deletion Enhances MMP-9 Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice.
Matrix metalloproteinase-2 deficiency impairs aortic atherosclerotic calcification in ApoE-deficient mice.
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury.
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Matrix metalloproteinase-2 regulates the expression of tissue inhibitor of matrix metalloproteinase-2.
Mechanisms underlying the impairment of ischemia-induced neovascularization in matrix metalloproteinase 2-deficient mice.
MMP-2: Is too low as bad as too high in the cardiovascular system?
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Pathologies of matrix metalloproteinase-2 underactivity: a perspective on a neglected condition 1.
gelatinase b deficiency
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion.
Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice.
Genetic Diseases, Inborn
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism.
Dermal fibroblasts from pseudoxanthoma elasticum patients have raised MMP-2 degradative potential.
Geographic Atrophy
MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration.
Gestational Trophoblastic Disease
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Giant Cell Arteritis
Elevated levels of 92-kd type IV collagenase (matrix metalloproteinase 9) in giant cell arteritis.
Macrophages contain 92-kd gelatinase (MMP-9) at the site of degenerated internal elastic lamina in temporal arteritis.
Metalloproteinase-2 and -9 in giant cell arteritis: involvement in vascular remodeling.
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Giant Cell Tumor of Bone
Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone.
Giant Cell Tumors
Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent.
Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone.
Gingival Diseases
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Gingival Overgrowth
Cyclosporin A inhibits production and activity of matrix metalloproteinases by gingival fibroblasts.
Evaluation of inductive effects of different concentrations of cyclosporine A on MMP-1, MMP-2, MMP-3, TIMP-1, and TIMP-2 in fetal and adult human gingival fibroblasts.
Local Inflammation Alters MMP-2 and MMP-9 Gelatinase Expression Associated with the Severity of Nifedipine-Induced Gingival Overgrowth: a Rat Model Study.
Mechanism of azithromycin treatment on gingival overgrowth.
Molecular events associated with ciclosporin?A-induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts.
Gingivitis
Biomarkers of periodontitis in oral fluids.
Changes in MMPs and inflammatory cells in experimental gingivitis.
Levels of metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-1 in gingival crevicular fluid of patients with periodontitis, gingivitis, and healthy gingiva.
[Expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model]
Glaucoma
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Alteration of MCP-1 and MMP-9 in aqueous humor is associated with secondary glaucoma in Fuchs uveitis syndrome.
Altered transcripts expression of matrix metalloproteinases and their tissue inhibitors in tenon capsule of patients with glaucoma.
Connective tissue growth factor and tissue inhibitor of matrix metalloproteinase-2 in patients with exfoliative glaucoma.
Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase.
Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
Identification of ocular matrix metalloproteinases present within the aqueous humor and iridocorneal drainage angle tissue of normal and glaucomatous canine eyes.
Increased expression of matrix metalloproteinases in mononuclear blood cells of normal-tension glaucoma patients.
Latanoprost therapy reduces the levels of TGF beta 1 and gelatinases in the aqueous humour of patients with exfoliative glaucoma.
Levels and activation of matrix metalloproteinases in aqueous humor are elevated in uveitis-related secondary glaucoma.
Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma.
The relationship between gelatinase A activity in aqueous humor and glaucoma.
Trabodenoson on trabecular meshwork rejuvenation: a comprehensive review of clinical data.
[Expression of matrix metalloproteinases and inhibitors on the scleral tissue of lamina cribrosa in rat with experimental chronic ocular hypertension]
Glaucoma, Angle-Closure
Altered transcripts expression of matrix metalloproteinases and their tissue inhibitors in tenon capsule of patients with glaucoma.
Glaucoma, Open-Angle
Altered transcripts expression of matrix metalloproteinases and their tissue inhibitors in tenon capsule of patients with glaucoma.
Correlations of TIMP2 and TIMP3 gene polymorphisms with primary open-angle glaucoma.
Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head.
Hyaluronic acid increases MMP-2 and MMP-9 expressions in cultured trabecular meshwork cells from patients with primary open-angle glaucoma.
Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma.
Levels and activation of matrix metalloproteinases in aqueous humor are elevated in uveitis-related secondary glaucoma.
The Protective Role of the -735C/T and the -1306C/T Polymorphisms of the MMP-2 Gene in the Development of Primary Open-angle Glaucoma.
Glioblastoma
Activated isoforms of MMP-2 are induced in U87 human glioma cells in response to beta-amyloid peptide.
Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma.
Activation of TIMP-2/progelatinase A complex by stromelysin.
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Adhesive and invasive features in gliomas.
Aldehyde dehydrogenase 1A1 circumscribes high invasive glioma cells and predicts poor prognosis.
Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression.
Arsenic Trioxide Induces Apoptosis and Incapacitates Proliferation and Invasive Properties of U87MG Glioblastoma Cells through a Possible NF-?B-Mediated Mechanism.
Autocrine Production of PDGF Stimulated by the Tenascin-C-Derived Peptide TNIIIA2 Induces Hyper-Proliferation in Glioblastoma Cells.
Bacitracin Inhibits the Migration of U87-MG Glioma Cells via Interferences of the Integrin Outside-in Signaling Pathway.
Calpain 2 is required for glioblastoma cell invasion: regulation of matrix metalloproteinase 2.
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme.
Chitosan-Doxycycline hydrogel: an MMP inhibitor/sclerosing embolizing agent as a new approach to endoleak prevention and treatment after endovascular aneurysm repair.
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma.
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Downregulation of Akt and FAK phosphorylation reduces invasion of glioblastoma cells by impairment of MT1-MMP shuttling to lamellipodia and downregulates MMPs expression.
Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro.
Effect of resveratrol on matrix metalloproteinase-2 (MMP-2) and Secreted Protein Acidic and Rich in Cysteine (SPARC) on human cultured glioblastoma cells.
Effect of Ukrain on matrix metalloproteinase-2 and Secreted Protein Acidic and Rich in Cysteine (SPARC) expression in human glioblastoma cells.
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.
Elevated levels of Mr 92,000 type IV collagenase during tumor growth in vivo.
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas.
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors.
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis.
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.
Green tea polyphenol (-)-epigallocatechin 3-gallate inhibits MMP-2 secretion and MT1-MMP-driven migration in glioblastoma cells.
Human chorionic gonadotropin ? induces cell motility via ERK1/2 and MMP-2 activation in human glioblastoma U87MG cells.
IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1.
In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion.
Increased expression of gelatinase-a and timp-2 in primary human glioblastomas.
Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity.
Localization of gelatinase activities in glioma tissues by film in situ zymography.
Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.
Low-dose chemotherapy combined with an antiangiogenic drug reduces human glioma growth in vivo.
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Matrix metalloproteinase-2 and -9 in glioblastoma: a trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma.
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1?.
Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells.
Moesin Up-regulation Is Associated with Enhanced Tumor Progression Imaged Non-invasively in an Orthotopic Mouse Model of Human Glioblastoma.
Naringin inhibits the invasion and migration of human glioblastoma cell via downregulation of MMP-2 and MMP-9 expression and inactivation of p38 signaling pathway.
PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene.
PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy.
PEITC inhibits human brain glioblastoma GBM 8401 cell migration and invasion through the inhibition of uPA, Rho A, and Ras with inhibition of MMP-2, -7 and -9 gene expression.
Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells.
Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP.
Signaling pathways mediating manganese-induced toxicity in human glioblastoma cells (u87).
Silencing microRNA-221/222 cluster suppresses glioblastoma angiogenesis by suppressor of cytokine signaling-3-dependent JAK/STAT pathway.
Specificity Protein 1 Expression Contributes to Bcl-w-Induced Aggressiveness in Glioblastoma Multiforme.
Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model.
Sulindac and its metabolites inhibit invasion of glioblastoma cells via down-regulation of Akt/PKB and MMP-2.
Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma.
Targeting the MMP-14/MMP-2/integrin ?v?3 axis with multispecific N-TIMP2-based antagonists for cancer therapy.
Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation.
TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells.
Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1.
Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line.
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Vascular endothelial growth factor expression correlates with matrix metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas.
Verbascoside Inhibits Glioblastoma Cell Proliferation, Migration and Invasion While Promoting Apoptosis Through Upregulation of Protein Tyrosine Phosphatase SHP-1 and Inhibition of STAT3 Phosphorylation.
[Corrigendum] Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma.
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
Glioma
A model of BmK CT in inhibiting glioma cell migration via matrix metalloproteinase-2 from experimental and molecular dynamics simulation study
A model of BmK CT in inhibiting glioma cell migration via matrix metalloproteinase-2 from experimental and molecular dynamics simulation study.
A potential strategy for high-grade gliomas: combination treatment with lithium chloride and BmK CT.
A role of matrix metalloproteinases produced by glioma-cells.
Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells.
Activated isoforms of MMP-2 are induced in U87 human glioma cells in response to beta-amyloid peptide.
Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation.
Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo.
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Activation of NMDA receptor of glutamate influences MMP-2 activity and proliferation of glioma cells.
Adenoviral vectors expressing fusogenic membrane glycoproteins activated via matrix metalloproteinase cleavable linkers have significant antitumor potential in the gene therapy of gliomas.
Adenovirus-mediated expression of BmK CT suppresses growth and invasion of rat C6 glioma cells
Adenovirus-mediated expression of BmK CT suppresses growth and invasion of rat C6 glioma cells.
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Adhesive and invasive features in gliomas.
All-trans retinoic acid inhibits migration, invasion and proliferation, and promotes apoptosis in glioma cells in vitro.
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway.
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2.
Anti-inflammatory effects of serum isolated from animals on intermittent feeding in C6 glioma cell line.
Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells.
Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes.
Antitumor progression potential of caffeic acid phenethyl ester involving p75(NTR) in C6 glioma cells.
Association of increased phosphatidylinositol 3-kinase signaling with increased invasiveness and gelatinase activity in malignant gliomas.
Association of matrix metalloproteinase 2 plasma level with response and survival in patients treated with bevacizumab for recurrent high-grade glioma.
Baicalein reduces the invasion of glioma cells via reducing the activity of p38 signaling pathway.
Bex2 is Critical for Migration and Invasion in Malignant Glioma Cells.
BmK CT and 125I-BmK CT suppress the invasion of glioma cells in vitro via matrix metalloproteinase-2.
BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitro.
BRMS1 suppresses glioma progression by regulating invasion, migration and adhesion of glioma cells.
c-Cbl regulates glioma invasion through matrix metalloproteinase 2.
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
CCL5 of glioma-associated microglia/macrophages regulates glioma migration and invasion via calcium-dependent matrix metalloproteinase 2.
CCR7 Mediates TGF-?1-Induced Human Malignant Glioma Invasion, Migration, and Epithelial-Mesenchymal Transition by Activating MMP2/9 Through the Nuclear Factor KappaB Signaling Pathway.
CD44 expression and MMP-2 secretion by mouse glioma cells: effect of interferon and anti-CD44 antibody.
CD73 Downregulation Decreases In Vitro and In Vivo Glioblastoma Growth.
Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas.
Chapter 4 - Applications of nanotechnology in molecular imaging of the brain.
CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells.
Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis.
Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2.
Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs.
Chronic Intermittent Ethanol Exposure Induces Upregulation of Matrix Metalloproteinase-9 in the Rat Medial Prefrontal Cortex and Hippocampus.
Combination of lithium chloride and pEGFP-N1-BmK CT effectively decreases proliferation and migration of C6 glioma cells.
Construction and Evaluation of the Tumor-Targeting, Cell-Penetrating Multifunctional Molecular Probe iCREKA.
Coronarin D suppresses proliferation, invasion and migration of glioma cells via activating JNK signaling pathway.
CTHRC1 mediates multiple pathways regulating cell invasion, migration and adhesion in glioma.
Cullin1 regulates proliferation, migration and invasion of glioma cells.
Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics.
Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma.
Decrease of endogenous vascular endothelial growth factor may not affect glioma cell proliferation and invasion.
Destruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain glioma.
Dexamethasone reduced invasiveness of human malignant glioblastoma cells through a MAPK phosphatase-1 (MKP-1) dependent mechanism.
Differential expression of laminin and fibronectin and of their related metalloproteinases in human glioma cell lines: relation to invasion.
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.
Dlxin-1, a member of MAGE family, inhibits cell proliferation, invasion and tumorigenicity of glioma stem cells.
Downregulation of astrocyte elevated gene-1 expression inhibits the development of vasculogenic mimicry in gliomas.
EFEMP2 is upregulated in gliomas and promotes glioma cell proliferation and invasion.
Effect of cisplatin and BCNU on MMP-2 levels in human glioblastoma cell lines in vitro.
Effect of photodynamic therapy combined with torasemide on the expression of matrix metalloproteinase 2 and sodium-potassium-chloride cotransporter 1 in rat peritumoral edema and glioma.
Effects of thalidomide on parameters involved in angiogenesis: an in vitro study.
Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide.
Exosomes from glioma cells induce a tumor-like phenotype in mesenchymal stem cells by activating glycolysis.
Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade.
Expression and function of chondroitin 4-sulfate and chondroitin 6-sulfate in human glioma.
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas.
Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas.
Expression of 72 kDa type IV collagenase and invasion activity of human glioma cells.
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Expression pattern of osteopontin splice variants and its functions on cell apoptosis and invasion in glioma cells.
FRK controls migration and invasion of human glioma cells by regulating JNK/c-Jun signaling.
Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma.
Gelatinase A expression in human malignant gliomas.
Gelatinolytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9 in rat brain after implantation of 9L rat glioma cells.
Genistein Suppression of Matrix Metalloproteinase 2 (MMP-2) and Vascular Endothelial Growth Factor (VEGF) Expression in Mesenchymal Stem Cell Like Cells Isolated from High and Low Grade Gliomas
Girdin, an actin-binding protein, is critical for migration, adhesion, and invasion of human glioblastoma cells.
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.
Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts.
Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta.
Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C.
In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion.
In vitro expression of MMP-2 and MMP-9 in glioma cells following exposure to inflammatory mediators.
In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture.
Increased expression of MMP-2 and MMP-9 indicates poor prognosis in glioma recurrence.
Increased invasive capacity of connexin43-overexpressing malignant glioma cells.
Induction of membrane-type-1 matrix metalloproteinase by epidermal growth factor-mediated signaling in gliomas.
Inflammatory cytokine modulation of matrix metalloproteinase expression and invasiveness of glioma cells in a 3-dimensional collagen matrix.
Inhibition of cell invasion by indomethacin on glioma cell lines: in vitro study.
Inhibition of glioblastoma growth and invasion by (125)I brachytherapy in rat glioma model.
Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones.
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity.
Inhibitory effect of penta-acetyl geniposide on C6 glioma cells metastasis by inhibiting matrix metalloproteinase-2 expression involved in both the PI3K and ERK signaling pathways.
Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes.
Invasion of brain tissue by primary glioma: evidence for the involvement of urokinase-type plasminogen activator as an activator of type IV collagenase.
Ionizing Radiation Enhances Matrix Metalloproteinase-2 Secretion and Invasion of Glioma Cells through Src/Epidermal Growth Factor Receptor-Mediated p38/Akt and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways.
Ionizing radiation-inducible miR-494 promotes glioma cell invasion through EGFR stabilization by targeting p190B RhoGAP.
Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines.
Lactate promotes glioma migration by TGF-beta2 dependent regulation of matrix metalloproteinase-2.
Layilin enhances the invasive ability of malignant glioma cells via SNAI1 signaling.
Local intracerebral delivery of endogenous inhibitors by osmotic minipumps effectively suppresses glioma growth in vivo.
Localization of gelatinase activities in glioma tissues by film in situ zymography.
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model.
Marchantin C: a potential anti-invasion agent in glioma cells.
Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma.
Matrix metalloproteinase-2 activation modulates glioma cell migration.
Matrix metalloproteinase-2 and -9 expression in astrocytic tumors.
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas.
Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells.
Metformin inhibits glioma cell U251 invasion by downregulation of fibulin-3.
MicroRNA-140-5p inhibits cell proliferation and invasion by regulating VEGFA/MMP2 signaling in glioma.
Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation.
miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase.
MiR-29c inhibits glioma cell proliferation, migration, invasion and angiogenesis.
MiR-338-5p Promotes Glioma Cell Invasion by Regulating TSHZ3 and MMP2.
miR-361-5p inhibits glioma migration and invasion by targeting SND1.
MMP-2 downregulation mediates differential regulation of cell death via ErbB-2 in glioma xenografts.
MMP-2 expression and correlation with pathology and MRI of glioma.
MMP-2 siRNA inhibits radiation-enhanced invasiveness in glioma cells.
Modulation of phorbol ester-induced regulation of matrix metalloproteinases and tissue inhibitors of metalloproteinases by SB203580, a specific inhibitor of p38 mitogen-activated protein kinase.
Molecular determinants of glioma cell migration and invasion.
Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9
Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9.
N-(2-18F-fluoropropionyl)-l-glutamate as a potential oncology tracer for PET imaging of glioma.
Neurokinin-1 receptor directly mediates glioma cell migration by up-regulation of matrix metalloproteinase-2 (MMP-2) and membrane type 1-matrix metalloproteinase (MT1-MMP).
Nodal promotes growth and invasion in human gliomas.
Non-apoptotic Fas signaling regulates invasiveness of glioma cells and modulates MMP-2 activity via NFkappaB-TIMP-2 pathway.
Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro.
Novel anti IGFBP2 single chain variable fragment inhibits glioma cell migration and invasion.
Osteopontin regulates human glioma cell invasiveness and tumor growth in mice.
Overexpression of EPAC2 reduces the invasion of glioma cells via MMP-2.
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Sp1-mediated signaling pathways.
Overexpression of riboflavin transporter 2 contributes toward progression and invasion of glioma.
pEGFP-N1-mediated BmK CT expression suppresses the migration of glioma.
PEX-producing human neural stem cells inhibit tumor growth in a mouse glioma model.
Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1.
PinX1 inhibits cell proliferation, migration and invasion in glioma cells.
Protein kinase C-mediated in vitro invasion of human glioma cells through extracellular-signal-regulated kinase and ornithine decarboxylase.
Proteolipid Protein 2 Overexpression Indicates Aggressive Tumor Behavior and Adverse Prognosis in Human Gliomas.
Psychological Stress Up-Regulates CD147 Expression Through Beta-Arrestin1/ERK to Promote Proliferation and Invasiveness of Glioma Cells.
PTEN gene transfer suppresses the invasive potential of human malignant gliomas by regulating cell invasion-related molecules.
Quantitative analysis of matrix metalloproteinase-2 mRNA expression in central and peripheral regions of gliomas.
Quercetin-induced downregulation of phospholipase D1 inhibits proliferation and invasion in U87 glioma cells.
Radiosynthesis and Preliminary Biological Evaluation of 18F-Fluoropropionyl-Chlorotoxin as a Potential PET Tracer for Glioma Imaging.
Rapid activation of matrix metalloproteinase-2 by glioma cells occurs through a posttranslational MT1-MMP-dependent mechanism.
Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid.
Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP.
regulation of the invasion and metastasis of human glioma cells by polypeptide N-acetylgalactosaminyltransferase 2.
Relationship between expression of XRCC1 and tumor proliferation, migration, invasion, and angiogenesis in glioma.
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2.
Retraction: MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells.
RhoA regulates invasion of glioma cells via the c-Jun NH2-terminal kinase pathway under hypoxia.
RNAi-mediated downregulation of MMP-2 activates the extrinsic apoptotic pathway in human glioma xenograft cells.
Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with ?5?1 integrin in glioma.
Rosiglitazone reduces cell invasiveness by inducing MKP-1 in human U87MG glioma cells.
Ryk is essential for Wnt-5a-dependent invasiveness in human glioma.
S-Adenosylhomocysteine Promotes the Invasion of C6 Glioma Cells via Increased Secretion of Matrix Metalloproteinase-2 in Murine Microglial BV2 Cells.
S100B-p53 disengagement by pentamidine promotes apoptosis and inhibits cellular migration via aquaporin-4 and metalloproteinase-2 inhibition in C6 glioma cells.
Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo.
Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells.
Secretion of matrix metalloproteinase-2 (72 kD gelatinase/type IV collagenase = gelatinase A) by malignant human glioma cell lines: implications for the growth and cellular invasion of the extracellular matrix.
Serine protease inhibitor (SERPIN) B1 suppresses cell migration and invasion in glioma cells.
Sevoflurane and thiopental preconditioning attenuates the migration and activity of MMP-2 in U87MG glioma cells.
Sevoflurane inhibits migration and invasion of glioma cells via regulating miR-34a-5p/MMP-2 axis.
Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated ?-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine.
Silencing HIWI suppresses the growth, invasion and migration of glioma cells.
Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2.
Single minded 2-s (SIM2-s) gene is expressed in human GBM cells and involved in GBM invasion.
SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells.
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model.
Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma.
Suppression of cell invasion on human malignant glioma cell lines by a novel matrix-metalloproteinase inhibitor SI-27: in vitro study.
Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.
Suppression of MMP-2 attenuates TNF-? induced NF-?B activation and leads to JNK mediated cell death in glioma.
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Tailoring Particle Size of Mesoporous Silica Nanosystem To Antagonize Glioblastoma and Overcome Blood-Brain Barrier.
Targeting Gelatinases with a Near-Infrared Fluorescent Cyclic His-Try-Gly-Phe Peptide.
Targeting the cytotoxicity of fusogenic membrane glycoproteins in gliomas through protease-substrate interaction.
The combined use of EphA2/MMP-2 expression and MRI findings contributes to the determination of cerebral glioma grade.
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
The expression and activation of matrix metalloproteinase-2 in rat brain after implantation of C6 rat glioma cells.
The expression of ATF3, MMP-2 and maspin in tissue chip of glioma.
The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades.
The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
The Impact of MMP-2 and Its Specific Inhibitor TIMP-2 Expression on the WHO Grade and Prognosis of Gliomas in Chinese Population: a Meta-Analysis.
The mechanical and pharmacological regulation of glioblastoma cell migration in 3D matrices.
The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.
TNF-? mediated MEK-ERK signaling in invasion with putative network involving NF-?B and STAT-6: a new perspective in glioma.
Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1.
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Tumor cell-matrix interaction: pericellular matrix degradation and metastasis.
Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling.
Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.
Wnt-5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP-2.
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
[Expression of CD147 and MMP-2 in human gliomas and its correlations with prognosis]
[Expression of Notch1, MMP-2 and MMP-9 and their significance in glioma patients].
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
[Isoliquiritigenin can inhibit migration and invasion of human glioma stem cells by down-regulating matrix metalloproteinases].
[The anti-cancer effect of ZR30 protein via targeting extracellular signal proteins of different cell subpopulations of glioma].
Gliosarcoma
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma.
Glomerulonephritis
Angiotensin-converting enzyme inhibition but not angiotensin II receptor blockade regulates matrix metalloproteinase activity in patients with glomerulonephritis.
Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis.
Expression of MMP-9 in mesangial cells and its changes in anti-GBM glomerulonephritis in WKY rats.
Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.
Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis.
Renal expression of matrix metalloproteinases in human ANCA-associated glomerulonephritis.
Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF-beta1 in patients with distinct types of primary glomerulonephritis.
Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex-mediated glomerulonephritis.
Transforming growth factor-beta 1 stimulates glomerular mesangial cell synthesis of the 72-kd type IV collagenase.
Treatment of experimental immune complex glomerulonephritis by sodium alginate.
[Role of matrix metalloproteinases in the progression of renal lesions]
Glomerulonephritis, IGA
Differential glomerular immunoexpression of matrix metalloproteinases MMP-2 and MMP-9 in idiopathic IgA nephropathy and Schoenlein-Henoch nephritis.
Glomerulonephritis, Membranous
Changes in serum concentrations of matrix metalloproteinases, tissue inhibitors of metalloproteinases and type IV collagen in patients with various types of glomerulonephritis.
Gelatinase secretion by glomerular epithelial cells.
Matrix metalloproteinase-2, matrix metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in the peripheral blood of patients with various glomerular diseases and their implication in pathogenetic lesions: study based on an enzyme-linked assay and immunohistochemical staining.
Glomerulosclerosis, Focal Segmental
Distinct metalloproteinase excretion patterns in focal segmental glomerulosclerosis.
Glucose Intolerance
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors in women with glucose intolerance in pregnancy and normal controls.
Glucose Metabolism Disorders
Soluble P-selectin and matrix metalloproteinase 2 levels are elevated in patients with diastolic dysfunction independent of glucose metabolism disorder or coronary artery disease.
Gout
Elevated plasma stromelysin levels in arthritis.
Granuloma
A comparative study of osteopontin and MMP-2 protein expression in peripheral and central giant cell granuloma of the jaws.
Association between bacteria occurring in the apical canal system and expression of bone-resorbing mediators and matrix metalloproteinases in apical periodontitis.
Continuous recruitment, co-expression of tumour necrosis factor-alpha and matrix metalloproteinases, and apoptosis of macrophages in gout tophi.
Cryptococcus neoformans pulmonary granuloma formation is associated with matrix metalloproteinase-2 expression.
Cytokines, MMP-2, and MMP-9 levels in patients with a solitary cysticercus granuloma.
Doxycycline hyclate: A schistosomicidal agent in vitro with immunomodulatory potential on granulomatous inflammation in vivo.
Expression of metalloproteinases (MMP-1, MMP-2, and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in schistosomal portal fibrosis.
Gene-expression analysis of matrix metalloproteinases 1 and 2 and their tissue inhibitors in chronic periapical inflammatory lesions.
Interstitial collagenase (MMP-1), gelatinase (MMP-2) and stromelysin (MMP-3) released by human fibroblasts cultured on acellular sarcoid granulomas (sarcoid matrix complex, SMC).
Large-pore PDS mesh compared to small-pore PG mesh.
Matrix metalloproteinase-2 and -9 in the granulomatous fibrosis of rats infected with Angiostrongylus cantonensis.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in mice with ocular toxocariasis.
Matrix metalloproteinases and their tissue inhibitors in the lesions of cardiac and pulmonary sarcoidosis: an immunohistochemical study.
N-acetyl-cysteine decreases the matrix-degrading capacity of macrophage-derived foam cells: new target for antioxidant therapy?
Polymeric meshes induce zonal regulation of matrix metalloproteinase-2 gene expression by macrophages and fibroblasts.
Schwann cells producing matrix metalloproteinases under Mycobacterium leprae stimulation may play a role in the outcome of leprous neuropathy.
Granuloma, Giant Cell
A comparative study of osteopontin and MMP-2 protein expression in peripheral and central giant cell granuloma of the jaws.
Granulomatous Disease, Chronic
Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils.
Graves Disease
Elevated serum concentrations of metalloproteinases (MMP-2, MMP-9) and their inhibitors (TIMP-1, TIMP-2) in patients with Graves' orbitopathy.
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
[Study of type I and IV collagenase activity in human thyroid diseases]
Graves Ophthalmopathy
[Serum gelatinases (MMP-2 and MMP-9) and VCAM-1 as a guideline in a therapeutic approach in Graves' ophthalmopathy.]
Guillain-Barre Syndrome
Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons.
Matrix metalloproteinase-9 is increased and correlates with severity in Guillain-Barré syndrome.
Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barré syndrome.
Hajdu-Cheney Syndrome
A novel matrix metalloproteinase 2 (MMP2) terminal hemopexin domain mutation in a family with multicentric osteolysis with nodulosis and arthritis with cardiac defects.
A novel mutation in the matrix metallopeptidase 2 coding gene associated with intrafamilial variability of multicentric osteolysis, nodulosis, and arthropathy.
Al-Aqeel Sewairi syndrome, a new autosomal recessive disorder with multicentric osteolysis, nodulosis and arthropathy. The first genetic defect of matrix metalloproteinase 2 gene.
Bisphosphonates in multicentric osteolysis, nodulosis and arthropathy (MONA) spectrum disorder - an alternative therapeutic approach.
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Loss of MMP-2 in osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis.
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Multicentric Osteolysis, Nodulosis, and Arthropathy in two unrelated children with matrix metalloproteinase 2 variants: Genetic-skeletal correlations.
Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.
Torg-Winchester syndrome: lack of efficacy of pamidronate therapy.
Hamartoma
Expression of matrix metalloproteinases and their endogenous tissue inhibitors in skin lesions from patients with tuberous sclerosis.
Head and Neck Neoplasms
Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis.
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Dehydrocrenatidine inhibits head and neck cancer cells invasion and migration by modulating JNK1/2 and ERK1/2 pathway and decreases MMP-2 expression.
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.
Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells.
Genistein elicits pleiotropic molecular effects on head and neck cancer cells.
Granulocyte colony-stimulating factor (G-CSF)-mediated signaling regulates type IV collagenase activity in head and neck cancer cells.
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Matrix metalloproteinase-2 as a target for head and neck cancer therapy.
The role of genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes in head and neck cancer.
Head Injuries, Closed
Distinct roles for metalloproteinases during traumatic brain injury.
Heart Defects, Congenital
Matrix metalloproteinases as candidate biomarkers in adults with congenital heart disease.
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Heart Diseases
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Angiotensin II downregulates ACE2-mediated enhancement of MMP-2 activity in human cardiofibroblasts.
Cardiac sarcomeric proteins: novel intracellular targets of matrix metalloproteinase-2 in heart disease.
Endogenous osteopontin induces myocardial CCL5 and MMP-2 activation that contributes to inflammation and cardiac remodeling in a mouse model of chronic Chagas heart disease.
Epigenetic Regulation of the N-Terminal Truncated Isoform of Matrix Metalloproteinase-2 (NTT-MMP-2) and Its Presence in Renal and Cardiac Diseases.
Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches.
Matrix metalloproteinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMP-2 level and increased risk of cardiovascular disease in systemic lupus erythematosus patients.
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
MMP-2 and TIMP-2 gene polymorphisms and susceptibility to atrial fibrillation in Chinese Han patients with hypertensive heart disease.
MMP-2: Is too low as bad as too high in the cardiovascular system?
Targeted deletion of matrix metalloproteinase 2 ameliorates myocardial remodeling in mice with chronic pressure overload.
Heart Failure
Activation and modulation of 72kDa matrix metalloproteinase-2 by peroxynitrite and glutathione.
Activation of matrix metalloproteinase dilates and decreases cardiac tensile strength.
Admission plasma neutrophil gelatinase associated lipocalin (NGAL) predicts worsening renal function during hospitalization and post discharge outcome in patients with acute heart failure.
Adrenoceptor blockade alters plasma gelatinase activity in patients with heart failure and MMP-9 promoter activity in a human cell line (ECV304).
Associations Between Neutrophil Gelatinase Associated Lipocalin, Neutrophil-to-Lymphocyte Ratio, Atrial Fibrillation and Renal Dysfunction in Chronic Heart Failure.
Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation.
Biomarkers and mortality in severe Chagas cardiomyopathy.
Cardiac resynchronization therapy in patients with chronic heart failure is associated with anti-inflammatory and anti-remodeling effects.
Cardiac transgenic matrix metalloproteinase-2 expression directly induces impaired contractility.
Changes in activities of circulating MMP-2 and MMP-9 in patients suffering from heart failure in relation to gender, hypertension and treatment: a cross-sectional study.
Changes of serum advanced glycation end products (AGEs), matrix metalloprotein-2 (MMP-2), and urinary microalbuminuria (mALB) in diabetic nephropathy and their predictive value for heart failure.
Circulating matrix metalloproteinase-2 but not matrix metalloproteinase-3, matrix metalloproteinase-9, or tissue inhibitor of metalloproteinase-1 predicts outcome in patients with congestive heart failure.
Circulating matrix metalloproteinase-2 is elevated in patients with congestive heart failure.
Clinical significance of matrix metalloproteinase (MMP)-2 in patients with acute heart failure.
Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients.
Comparison between admission natriuretic peptides, NGAL and sST2 testing for the prediction of worsening renal function in patients with acutely decompensated heart failure.
Comparison of levels of matrix metalloproteinase-2 and -3 in patients with ischemic cardiomyopathy versus nonischemic cardiomyopathy.
Comparison of predictive value of NT-proBNP, sST2 and MMPs in heart failure patients with different ejection fractions.
Cycloastragenol ameliorates experimental heart damage in rats by promoting myocardial autophagy via inhibition of AKT1-RPS6KB1 signaling.
Differences in the association between behavior and neutrophil gelatinase-associated lipocalin in male and female rats after coronary artery ligation.
Down-regulation of matrix metalloproteinase-9 (MMP-9) expression in the myocardium of congestive heart failure patients.
Effect of atorvastatin on non-ischemic heart failure and matrix metalloproteinase-2 and 9 in rats.
Effect of typhaneoside on ventricular remodeling and regulation of PI3K/Akt/mTOR pathway.
Ethanol extract from Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling through down-regulating matrix metalloproteinase-2 and -9 activity and myocardial apoptosis in rats with congestive heart failure.
Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats.
Heart failure and role of circulating MMP-2 and MMP-9.
Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2.
Hydrogen sulfide mitigates transition from compensatory hypertrophy to heart failure.
Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure.
Immediate administration of atorvastatin decreased the serum MMP-2 level and improved the prognosis for acute heart failure.
Impact of metalloproteinases on left ventricular remodeling and heart failure events in patients with hypertrophic cardiomyopathy.
Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensated Heart Failure.
Influence of spironolactone on matrix metalloproteinase-2 in acute decompensated heart failure.
Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure.
Interstitial remodeling in beta1-adrenergic receptor transgenic mice.
Levosimendan use reduces matrix metalloproteinase-2 in patients with decompensated heart failure.
Long-term therapy with the acorn cardiac support device normalizes gene expression of growth factors and gelatinases in dogs with heart failure.
Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix.
Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction.
Matrix Metalloproteinase-2 Polymorphisms in Chronic Heart Failure: Relationship with Susceptibility and Long-Term Survival.
Matrix Metalloproteinase-2 predicts mortality in patients with acute coronary syndrome.
Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3.
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
Metalloproteinases 2 and 9 are increased in plasma of patients with heart failure.
Metalloproteinases-2 and -9 predict left ventricular remodeling after myocardial infarction.
MMP-2 and TIMP-2 in Patients with Heart Failure and Chronic Kidney Disease.
MMP-2/TIMP-2/TIMP-4 versus MMP-9/TIMP-3 in transition from compensatory hypertrophy and angiogenesis to decompensatory heart failure.
Neurohormonal activation is associated with increased levels of plasma matrix metalloproteinase-2 in human heart failure.
Plasma Biomarkers Reflecting Profibrotic Processes in Heart Failure With a Preserved Ejection Fraction: Data From the Prospective Comparison of ARNI With ARB on Management of Heart Failure With Preserved Ejection Fraction Study.
Plasma concentrations of matrix metalloproteinase-2, tissue inhibitor of metalloproteinase-1 and osteopontin reflect severity of heart failure in DOCA-salt hypertensive rat.
Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.
Polymorphisms of MMP-2 Gene are Associated With Systolic Heart Failure Risk in Han Chinese.
Prolargin and matrix metalloproteinase-2 in heart failure after heart transplantation and their association with haemodynamics.
Quantification of diffuse myocardial fibrosis using CMR extracellular volume fraction and serum biomarkers of collagen turnover with histologic quantification as standard of reference.
Relationship Between Myocardial Redox State and Matrix Metalloproteinase Activity in Patients on Left Ventricular Assist Device Support.
Selective disruption of MMP-2 gene exacerbates myocardial inflammation and dysfunction in mice with cytokine-induced cardiomyopathy.
Serum MMP-9 activity as a diagnosing marker for the developing heart failure of post MI patients.
Structural remodelling in heart failure: gelatinase induction.
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
Targeting MMP-2 to treat ischemic heart injury.
Temporal regulation of extracellular matrix components in transition from compensatory hypertrophy to decompensatory heart failure.
The influence of oral copper-methionine on matrix metalloproteinase-2 gene expression and activation in right-sided heart failure induced by cold temperature: A broiler chicken perspective.
TIMP-2 mutant decreases MMP-2 activity and augments pressure overload induced LV dysfunction and heart failure.
Two MMP-2 promoter polymorphisms (-790T/G and -735C/T) in chronic heart failure.
Urinary neutrophil gelatinase associated lipocalin (NGAL), a marker of tubular damage, is increased in patients with chronic heart failure.
Water-soluble alkaloids extracted from Aconiti Radix lateralis praeparata protect against chronic heart failure in rats via a calcium signaling pathway.
[Effects of angiotensin II receptor antagonism on matrix metalloproteinases and fibronectin in rats with experimental myocardial infarction]
[Effects of bone marrow mesenchymal stem cells transplantation on heart function and ventricular remodeling in rats with isoproterenol-induced congestive heart failure]
[Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion]
Heart Failure, Systolic
A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity.
N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure.
Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.
Polymorphisms of MMP-2 Gene are Associated With Systolic Heart Failure Risk in Han Chinese.
Heart Rupture
Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice.
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice.
Temporal changes in matrix metalloproteinase expression and inflammatory response associated with cardiac rupture after myocardial infarction in mice.
Toll-like receptor 7 deficiency promotes survival and reduces adverse left ventricular remodelling after myocardial infarction.
Trimetazidine suppresses oxidative stress, inhibits MMP-2 and MMP-9 expression, and prevents cardiac rupture in mice with myocardial infarction.
Twinkle overexpression prevents cardiac rupture after myocardial infarction by alleviating impaired mitochondrial biogenesis.
Heart Septal Defects, Ventricular
Circulating matrix metalloproteinase-2 and -9 enzyme activities in the children with ventricular septal defect.
HELLP Syndrome
Placental expression of proteases and their inhibitors in patients with HELLP syndrome.
Hemangioma
Activation of matrix metalloproteinase (MMP)-2 by membrane type 1-MMP and abnormal immunolocalization of the basement membrane components laminin and type IV collagen in canine spontaneous hemangiosarcomas.
Evaluation of Effect of Propranolol on Serum Vascular Endothelial Growth Factor and Tissue Inhibitor of Metalloproteinase-2 Levels in Infantile Hemangioma.
Inhibition of matrix metalloproteinases by over-expression of tissue inhibitor of metalloproteinase-2 inhibits the growth of experimental hemangiomas.
Serum cytokine profiles in infants with infantile hemangiomas on oral propranolol treatment: VEGF and bFGF, potential biomarkers predicting clinical outcomes.
[Study the effect of antisense MMP-2 by transfection of ad-aMMP-2 on vascular endothelial cells from human proferating hemangiomas in vitro]
Hemangioma, Cavernous, Central Nervous System
Expression of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) in cerebral cavernous malformations: immunohistochemical analysis of MMP-2, -9 and TIMP-2.
Hemangiosarcoma
Inhibition of endoglin exerts anti-tumor effects through the regulation of non-Smad TGF-? signaling in angiosarcoma.
Hematologic Neoplasms
Association of MMP-2 (-1306 C>T), MMP-9 (-1562 C>T) Gene Polymorphism and the Formation of the Hematological Malignancies.
Inhibitors of gelatinases (MMP-2 and MMP-9) for the management of hematological malignancies.
Is dual inhibition of metalloenzymes HDAC-8 and MMP-2 a potential pharmacological target to combat hematological malignancies?
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
[Effect of As(2)O(3) on Expressions of COX-2 and Matrix Metalloproteinases in SGC7901 and K562 Cells.]
Hematoma, Subdural, Chronic
Role of MMP-2, MMP-9 and VEGF in the development of chronic subdural hematoma.
[Role of matrix metalloproteinase in transformation of subdural effusion into chronic subdural hematoma]
Hemochromatosis
Elevated serum type IV collagen: a sensitive indicator of the presence of cirrhosis in haemochromatosis.
Evidence for altered hepatic matrix degradation in genetic haemochromatosis.
Hemorrhagic Stroke
Different expression of ubiquitin C-terminal hydrolase-L1 and ?II-spectrin in ischemic and hemorrhagic stroke: Potential biomarkers in diagnosis.
Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke.
Intranasal delivery of hypoxia-preconditioned bone marrow-derived mesenchymal stem cells enhanced regenerative effects after intracerebral hemorrhagic stroke in mice.
MMP-2/MMP-9 plasma level and brain expression in Cerebral Amyloid Angiopathy-associated hemorrhagic stroke.
Hepatic Veno-Occlusive Disease
Sinusoidal obstruction syndrome (veno-occlusive disease) in the rat is prevented by matrix metalloproteinase inhibition.
Hepatitis
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Correlation between plasma levels of matrix metalloproteinase (MMP)-9 /MMP-2 ratio and alpha-fetoproteins in chronic hepatitis carrying hepatitis B virus.
Elevated MTSS1 expression associated with metastasis and poor prognosis of residual hepatitis B-related hepatocellular carcinoma.
Expression and cDNA sequence of matrix metalloproteinase-2 (MMP-2) in a mammalian model of human disease processes: Tupaia belangeri.
Matrix metalloproteinases and their inhibitors in acute viral hepatitis.
MMP-2 gene expression at mRNA level in HBV and HCV infected patients.
Hepatitis B
Correlation between plasma levels of matrix metalloproteinase (MMP)-9 /MMP-2 ratio and alpha-fetoproteins in chronic hepatitis carrying hepatitis B virus.
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Hepatitis B, Chronic
Clinical utility of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 concentrations in the assessment of liver fibrosis due to chronic hepatitis B.
Differential expression of matrix metalloproteinases in viral and non-viral chronic liver diseases.
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Matrix metalloproteinases and their tissue inhibitors in children with chronic hepatitis B treated with lamivudine.
MMP-2 gene expression at mRNA level in HBV and HCV infected patients.
Significant differences in serum activities of matrix metalloproteinase-2 and -9 between HCV- and HBV-infected patients and carriers.
The Clinical Significance of Serum Apoptotic Cytokeratin 18 Neoepitope M30 (CK-18 M30) and Matrix Metalloproteinase 2 (MMP-2) Levels in Chronic Hepatitis B Patients with Cirrhosis.
[Effect of oxymatrine on serum matrix metalloproteinase-2 and its inhibitor in patients with chronic hepatitis B and liver cirrhosis]
Hepatitis C
Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells.
Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C.
Differential expression of matrix metalloproteinases in viral and non-viral chronic liver diseases.
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways.
Is neutrophil gelatinase associated lipocalin useful in hepatitis C virus infection?
MMP-2 gene expression at mRNA level in HBV and HCV infected patients.
Hepatitis C, Chronic
Circulating matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as serum markers of fibrosis in patients with chronic hepatitis C. Relationship to interferon response.
Clinical role of serum and tissue matrix metalloprotease-9 expression in chronic HCV patients treated with pegylated IFN-alpha2b and ribavirin.
Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C.
Diagnostic potential of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as non-invasive markers of hepatic fibrosis in patients with HCV related chronic liver disease.
Diagnostic value of serum markers of connective tissue turnover for predicting histological staging and grading in patients with chronic hepatitis C.
Effect of antiviral therapy on markers of fibrogenesis in patients with chronic hepatitis C.
Effects of interferon plus ribavirin treatment on NF-kappaB, TGF-beta1, and metalloproteinase activity in chronic hepatitis C.
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases -1 and -2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: comparison using ROC analysis.
Significance of serum matrix metalloproteinases and their inhibitors on the antifibrogenetic effect of interferon-alfa in chronic hepatitis C patients.
Hepatitis, Chronic
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Evaluation of serum matrix metalloproteinase (MMP)-9 to MMP-2 ratio as a biomarker in hepatocellular carcinoma.
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential.
Serum levels of tissue inhibitor of metalloproteinases-2 and of precursor form of matrix metalloproteinase-2 in patients with liver disease.
Usefulness of non-invasive markers for predicting liver cirrhosis in patients with chronic hepatitis B.
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
[Expression of matrix metalloproteinase-2 and its tissue inhibitor in liver tissue of patients with chronic hepatitis and cirrhosis]
Hepatopulmonary Syndrome
Correlations of MMP-2 and MMP-9 gene polymorphisms with the risk of hepatopulmonary syndrome in cirrhotic patients: A case-control study.
Herpes Zoster
Caspase-1 Inhibitor Prevents Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage in Mice.
Effects of Kaixinjieyu, a Chinese herbal medicine preparation, on neurovascular unit dysfunction in rats with vascular depression.
Sperm Cohort-Specific Zinc Signature Acquisition and Capacitation-Induced Zinc Flux Regulate Sperm-Oviduct and Sperm-Zona Pellucida Interactions.
Sperm matrix metalloproteinase-2 activity increased in pregnant couples treated with intrauterine insemination: a prospective case control study.
T cell-mediated biliary epithelial-to-mesenchymal transition in liver allograft rejection.
Hidradenitis Suppurativa
Tumour Necrosis Factor-alpha and Matrix Metalloproteinase-2 are Expressed Strongly in Hidradenitis Suppurativa.
Hirsutism
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Histiocytoma, Benign Fibrous
Expression of 72 kilodalton and 92 kilodalton type IV collagenase in malignant fibrous histiocytomas and dermatofibromas.
Expression of MMP-2, MMP-9 and MMP-11 in dermatofibroma and dermatofibrosarcoma protuberans.
Immunohistochemical study of membrane type-matrix metalloproteinases (MT-MMPs) and matrix metalloproteinase-2 (MMP-2) in dermatofibroma and malignant fibrous histiocytoma.
Histiocytoma, Malignant Fibrous
Expression of 72 kilodalton and 92 kilodalton type IV collagenase in malignant fibrous histiocytomas and dermatofibromas.
Immunohistochemical study of membrane type-matrix metalloproteinases (MT-MMPs) and matrix metalloproteinase-2 (MMP-2) in dermatofibroma and malignant fibrous histiocytoma.
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
HIV Infections
72-kDa and 92-kDa gelatinases in saliva of patients with human immunodeficiency virus infection.
An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection.
Effects of norepinephrine, HIV type 1 infection, and leukocyte interactions with endothelial cells on the expression of matrix metalloproteinases.
Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia.
HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration.
Matrix metalloproteinase levels in early HIV infection and relation to in vivo brain status.
Matrix metalloproteinase-2 on activated platelets triggers endothelial PAR-1 initiating atherosclerosis.
Modulations of 92kDa gelatinase B and its inhibitors are associated with HIV-1 infection in human macrophage cultures.
Hodgkin Disease
Diverse role of MMP-2 and MMP-9 in the clinicopathological behavior of Hodgkin's lymphoma.
Immunohistochemical expression of angiogenic cytokines in childhood Hodgkin lymphoma.
Plasma MMP-2-TIMP-2 complex levels measured during follow-up predict a risk of relapse in patients with malignant lymphoma.
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in Hodgkin's and non-Hodgkin's lymphoma.
HTLV-I Infections
Expression of metalloproteinase-2 (gelatinase A) in labial salivary glands of patients with Sjögren's syndrome with HTLV-I infection.
Human T-cell leukemia virus type I Tax transactivates the matrix metalloproteinase-9 gene: potential role in mediating adult T-cell leukemia invasiveness.
Hyaline Membrane Disease
Gelatinase activities in the airways of premature infants and development of bronchopulmonary dysplasia.
Hydatidiform Mole
Expression of matrix metalloproteinase-2 and mutant p53 is increased in hydatidiform mole as compared with normal placenta.
Overexpression of GRP78 in complete hydatidiform moles.
Reduced expression of tissue inhibitor of metalloproteinase (TIMP)-2 in gestational trophoblastic diseases.
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
[Prediction of malignant transformation of hydatidiform mole by mRNA determination of matrix metalloproteinases and tissue inhibitor of metalloproteinases]
Hydatidiform Mole, Invasive
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Hydronephrosis
Can serum Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 help in decision making for surgery in antenatally dedected hydronephrosis.
Matrix Metalloproteinase-2 Knockout and Heterozygote Mice Are Protected from Hydronephrosis and Kidney Fibrosis after Unilateral Ureteral Obstruction.
Selected Metal Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases as Potential Biomarkers for Tubulointerstitial Fibrosis in Children with Unilateral Hydronephrosis.
Hyperalgesia
Analgesic Effect of Methane Rich Saline in a Rat Model of Chronic Inflammatory Pain.
Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome.
DNMT3b SUMOylation Mediated MMP-2 Upregulation Contribute to Paclitaxel Induced Neuropathic Pain.
Effect of a Novel, Orally Active Matrix Metalloproteinase-2 and -9 Inhibitor in Spinal and Trigeminal Rat Models of Neuropathic Pain.
Functional interplay between gelatinases and hyperalgesia in endotoxin-induced localized inflammatory pain.
Growth hormone releasing hormone reverses endotoxin-induced localized inflammatory hyperalgesia without reducing the upregulated cytokines, nerve growth factor and gelatinase activity.
NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9.
Hypercholesterolemia
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells.
Hyperglycemia
Defining the Regulated Secreted Proteome of Rodent Adipocytes upon the Induction of Insulin Resistance.
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy.
Evidence of proatherogenic inflammation in polycystic ovary syndrome.
Hyperglycemia-Induced Modulation of the Physiognomy and Angiogenic Potential of Fibroblasts Mediated by Matrix Metalloproteinase-2: Implications for Venous Stenosis Formation Associated with Hemodialysis Vascular Access in Diabetic Milieu.
Hyperglycemic condition during puberty increases collagen fibers deposition in the prostatic stroma and reduces MMP-2 activity.
Inhibition of diabetic nephropathy by a GH antagonist: a molecular analysis.
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells.
Lercanidipine decreases vascular matrix metalloproteinase-2 activity and protects against vascular dysfunction in diabetic rats.
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
Role of TSPO/VDAC1 Upregulation and Matrix Metalloproteinase-2 Localization in the Dysfunctional Myocardium of Hyperglycaemic Rats.
Hyperhomocysteinemia
Homocysteine enriched diet leads to prolonged QT interval and reduced left ventricular performance in telemetric monitored mice.
Induction of oxidative stress by homocyst(e)ine impairs endothelial function.
The role of homocysteine in seminal vesicles remodeling in rat.
Hyperinsulinism
Effects of insulin and free fatty acids on matrix metalloproteinases.
In vivo effects of insulin and free fatty acids on matrix metalloproteinases in rat aorta.
Hyperlipidemias
Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition.
Hyperostosis
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Hypersensitivity
Expression of matrix metalloproteinase-9 and -2 in pediatric chronic otitis media with effusion.
Matrix metalloproteinase-2 promoter variability in psoriasis.
Hypertension
Adiponectin as an Independent Predictor of Left Ventricular Hypertrophy in Nondiabetic Patients With Hypertension.
Age- and Phenotype-Dependent Changes in Circulating MMP-2 and MMP-9 Activities in Normotensive and Hypertensive Rats.
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase.
Alterations in vascular matrix metalloproteinase due to ageing and chronic hypertension: effects of endothelin receptor blockade.
Antioxidant effect of doxycycline decreases MMP activity and blood pressure in SHR.
Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension.
Atorvastatin and sildenafil decrease vascular TGF-? levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension.
Cell-specific and endothelium-dependent regulations of matrix metalloproteinase-2 in rat aorta.
Changes in activities of circulating MMP-2 and MMP-9 in patients suffering from heart failure in relation to gender, hypertension and treatment: a cross-sectional study.
Changes of serum advanced glycation end products (AGEs), matrix metalloprotein-2 (MMP-2), and urinary microalbuminuria (mALB) in diabetic nephropathy and their predictive value for heart failure.
Common matrix metalloproteinase 2 gene haplotypes may modulate left ventricular remodelling in hypertensive patients.
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Consistent Alterations of Circulating Matrix Metalloproteinases Levels in Untreated Hypertensives and in Spontaneously Hypertensive Rats: A Relevant Pharmacological Target.
Does Arterial Hypertension Affect Plasma Levels of Matrix Metalloproteinases and Their Tissue Inhibitors in Patients with Stable Coronary Artery Disease? A Preliminary Study.
Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients.
Dynamics of Distribution of Capillaries with Matrix Metalloproteinase-2 and Its Tissue Inhibitor in Rat Brain during Development of Experimental Hypertension.
Estrogen deficiency-induced alterations of vascular MMP-2, MT1-MMP, and TIMP-2 in ovariectomized rats.
Euterpe oleracea Mart.-derived polyphenols prevent endothelial dysfunction and vascular structural changes in renovascular hypertensive rats: role of oxidative stress.
Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy.
Evidence of early involvement of matrix metalloproteinase-2 in lead-induced hypertension.
Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats.
Exogenous l-arginine reduces matrix metalloproteinase-2 and -9 activities and oxidative stress in patients with hypertension.
Expression and response to Angiotensin-converting enzyme inhibition of matrix metalloproteinases 2 and 9 in renal glomerular damage in young transgenic rats with Renin-dependent hypertension.
Expression of matrix metalloproteinases MMP-2 and MMP-9 is altered during nephrogenesis in fetuses from diabetic rats.
Expression of the recessive glomerulosclerosis gene Mpv17 regulates MMP-2 expression in fibroblasts, the kidney, and the inner ear of mice.
Genetic factors for lone atrial fibrillation.
Hypertension, augmented activity of matrix metalloproteinases-2 and -9 and angiogenic imbalance in hypertensive pregnancy are attenuated by doxycycline.
Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats.
Impact of Biomarkers of Inflammation and Extracellular Matrix Turnover on the Outcome of Atrial Fibrillation Ablation: Importance of Matrix Matalloproteinase-2 as a Predictor of Atrial Fibrillation Recurrence.
Impact of matrix metalloproteinase-2 levels on long-term outcome following pharmacological or electrical cardioversion in patients with atrial fibrillation.
Increased Circulating Tissue Inhibitor of Metalloproteinase-2 Is Associated With Resistant Hypertension.
Increased Matrix Metalloproteinase 2 Activity in the Human Internal Mammary Artery Is Associated with Ageing, Hypertension, Diabetes and Kidney Dysfunction.
Inhibition of matrix metalloproteinase-2 improves endothelial function and prevents hypertension in insulin resistant rats.
Involvement of matrix metalloproteinase-2 in medial hypertrophy of pulmonary arterioles in broiler chickens with pulmonary arterial hypertension.
Lercanidipine reduces matrix metalloproteinase-2 activity and reverses vascular dysfunction in renovascular hypertensive rats.
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Matrix metalloproteinase (MMP)-2 activation by oxidative stress decreases aortic calponin-1 levels during hypertrophic remodeling in early hypertension.
Matrix metalloproteinase (MMP)-2 decreases calponin-1 levels and contributes to arterial remodeling in early hypertension.
Matrix metalloproteinase -2, -9 and arterial stiffness in children and adolescents: The role of chronic kidney disease, diabetes, and hypertension.
Matrix Metalloproteinase 2 as a Potential Mediator of Vascular Smooth Muscle Cell Migration and Chronic Vascular Remodeling in Hypertension.
Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension.
Matrix metalloproteinase 9 polymorphisms and systemic lupus erythematosus: correlation with systemic inflammatory markers and oxidative stress.
Matrix metalloproteinase-2 -735C/T polymorphism is associated with resistant hypertension in a specialized outpatient clinic in Brazil.
Matrix Metalloproteinase-2 Activity is Associated with Divergent Regulation of Calponin-1 in Conductance and Resistance Arteries in Hypertension-induced Early Vascular Dysfunction and Remodelling.
Matrix metalloproteinase-2 and -9 in glioblastoma: a trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma.
Matrix Metalloproteinase-2 Mediates a Mechanism of Metabolic Cardioprotection Consisting of Negative Regulation of the Sterol Regulatory Element-Binding Protein-2/3-Hydroxy-3-Methylglutaryl-CoA Reductase Pathway in the Heart.
Matrix metalloproteinase-2, -9, and tissue inhibitor of metalloproteinase-1 in patients with hypertension.
Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness.
Matrix Metalloproteinases in Vascular Disease - A Potential Therapeutic Target?
Matrix metalloproteinases: discrete elevations in essential hypertension and hypertensive end-stage renal disease.
Mechanical stretch enhances the expression and activity of osteopontin and MMP-2 via the Akt1/AP-1 pathways in VSMC.
Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats.
MMP inhibition attenuates hypertensive eccentric cardiac hypertrophy and dysfunction by preserving troponin I and dystrophin.
MMP-2 and MMP-9 contribute to the angiogenic effect produced by hypoxia/15-HETE in pulmonary endothelial cells.
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
MMP-2 and sTNF-R1 Variability in Patients with Essential Hypertension: 1-Year Follow-Up Study.
MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats.
Nebivolol attenuates prooxidant and profibrotic mechanisms involving TGF-? and MMPs, and decreases vascular remodeling in renovascular hypertension.
New Insights into the Role of Matrix Metalloproteinases in Preeclampsia.
Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects.
Polymorphisms in gene MMP-2 modify the association of cadmium exposure with hypertension risk.
Pyrrolidine dithiocarbamate downregulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodeling in renovascular hypertension.
Reversal of deleterious effect of hypertension on the liver by inhibition of endoplasmic reticulum stress.
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
Role of MMP-2 and MMP-9 in resistance to drug therapy in patients with resistant hypertension.
Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension.
Suppression of ?1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats.
Synergistic effect of mitral expression of tissue inhibitor of metalloproteinase-2 with hypertension on the occurrence of mitral chordae tendinae rupture.
Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-? in renovascular hypertension-induced cardiac hypertrophy.
Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension.
TNF-? inhibition decreases MMP-2 activity, reactive oxygen species formation and improves hypertensive vascular hypertrophy independent of its effects on blood pressure.
[Metalloproteinases MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 levels in children and adolescents with type 1 diabetes.]
[The markers of inflammation reaction and dysfunction of endothelium in pregnant women with hypertension disorders of various genesis].
Hypertension, Portal
Neutrophil gelatinase associated lipocalin and Cystatin C in cirrhosis and portal hypertension: Relations to organ extraction and dysfunction.
Hypertension, Pregnancy-Induced
A stromal interaction molecule 1 variant up-regulates matrix metalloproteinase-2 expression by strengthening nucleoplasmic Ca(2+) signaling.
Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy.
Effects of Matrix Metalloproteinase (MMP)-2 Polymorphisms on Responsiveness to Antihypertensive Therapy of Women with Hypertensive Disorders of Pregnancy.
Matrix metalloproteinase-2 C-735T and its interaction with matrix metalloproteinase-7 A-181G polymorphism are associated with the risk of preeclampsia: influence on total antioxidant capacity and blood pressure.
Matrix metalloproteinase-2 is elevated in midtrimester amniotic fluid prior to the development of preeclampsia.
[Expression of trophoblast invasion related genes mRNA and protein in human placenta in preeclampsia]
Hypertension, Pulmonary
Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with pulmonary hypertension.
Effects of Dietary Copper-Methionine on Matrix Metalloproteinase-2 in the Lungs of Cold-Stressed Broilers as an Animal Model for Pulmonary Hypertension.
Gelatinase expression in pulmonary arteries during experimental pulmonary hypertension.
Gene expressions of nitric oxide synthase and matrix metalloproteinase-2 in monocrotaline-induced pulmonary hypertension in rats after bosentan treatment.
hsa-miR-106b-5p participates in the development of chronic thromboembolic pulmonary hypertension via targeting matrix metalloproteinase 2.
Immunohistochemical study of endothelin-1 and matrix metalloproteinases in plexogenic pulmonary arteriopathy.
L-arginine attenuates acute pulmonary embolism-induced increases in lung matrix metalloproteinase-2 and matrix metalloproteinase-9.
Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9.
Hypertension, Renovascular
Atorvastatin and sildenafil decrease vascular TGF-? levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension.
Comparative study on antioxidant effects and vascular matrix metalloproteinase-2 downregulation by dihydropyridines in renovascular hypertension.
Dynamics of Distribution of Capillaries with Matrix Metalloproteinase-2 and Its Tissue Inhibitor in Rat Brain during Development of Experimental Hypertension.
Quercetin decreases the activity of matrix metalloproteinase-2 and ameliorates vascular remodeling in renovascular hypertension.
Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension.
The Nuclear Factor kappaB Inhibitor Pyrrolidine Dithiocarbamate Prevents Cardiac Remodelling and Matrix Metalloproteinase-2 Up-Regulation in Renovascular Hypertension.
Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.
Hypertriglyceridemia
Management of cardiac fibrosis in diabetic rats; the role of peroxisome proliferator activated receptor gamma (PPAR-gamma) and calcium channel blockers (CCBs).
Hypertrophy, Left Ventricular
Effect of phentolamine on myocardial extracellular matrix of cardiac remodeling in rats.
Effects of crocetin on the matrix metalloproteinases in cardiac hypertrophy induced by norepinephrine in rats.
Excessive activation of matrix metalloproteinases coincides with left ventricular remodeling during transition from hypertrophy to heart failure in hypertensive rats.
Matrix metalloproteinase-2 -735C/T polymorphism is associated with resistant hypertension in a specialized outpatient clinic in Brazil.
Hypertrophy, Right Ventricular
Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats.
Inhaled PLGA Particles of Prostaglandin E1 Ameliorate Symptoms and Progression of Pulmonary Hypertension at a Reduced Dosing Frequency.
Hypoalbuminemia
Identification of matrix metalloproteinase-2 and -9 activities within the intestinal mucosa of dogs with chronic enteropathies.
Hypotension
Small interfering RNA targeting focal adhesion kinase prevents cardiac dysfunction in endotoxemia.
Hypoxia-Ischemia, Brain
Correlation of MMP-2 gene polymorphism with neonatal hypoxic-ischemic encephalopathy.
Idiopathic Interstitial Pneumonias
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias.
Idiopathic Pulmonary Fibrosis
Matrix metalloproteinase-2, -7, and -9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases.
Matrix metalloproteinase-9 in lung remodeling.
IgA Vasculitis
A case of anaphylactoid purpura with multiple blister formation: possible pathophysiological role of gelatinase (MMP-9).
Ileitis
Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice.
Immune System Diseases
Characterization of porcine MMP-2 and its association with immune traits.
Infarction, Middle Cerebral Artery
Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia.
Brain regional and cellular localization of gelatinase activity in rat that have undergone transient middle cerebral artery occlusion.
Different expression of ubiquitin C-terminal hydrolase-L1 and ?II-spectrin in ischemic and hemorrhagic stroke: Potential biomarkers in diagnosis.
Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats.
Matrix metalloproteinase-2 deletions protect against hemorrhagic transformation after 1h of cerebral ischemia and 23h of reperfusion.
Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats.
Tissue inhibitor of metalloproteinases protect blood-brain barrier disruption in focal cerebral ischemia.
Infections
A role for matrix metalloproteinase-9 in pathogenesis of urogenital Chlamydia muridarum infection in mice.
A role for the 72 kDa gelatinase (MMP-2) and its inhibitor (TIMP-2) in human parturition, premature rupture of membranes and intraamniotic infection.
Ablation of matrix metalloproteinase-9 increases severity of viral myocarditis in mice.
Activation of human progelatinase A/promatrix metalloproteinase 2 by Escherichia coli-derived serine proteinase.
Activation of MMP-9 by human lung epithelial cells in response to cystic fibrosis associated pathogen Burkholderia cenocepacia reduced wound healing in vitro.
Activity of matrix metalloproteinase 2 and 9 isoforms in sputum samples from individuals infected with M. tuberculosis.
Adenoviral vectors expressing fusogenic membrane glycoproteins activated via matrix metalloproteinase cleavable linkers have significant antitumor potential in the gene therapy of gliomas.
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Adrenal Steroids Modulate Fibroblast-Like Synoviocytes Response During B. abortus Infection.
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-?B Ligand and Tumor Necrosis Factor Alpha Secretion.
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
Chlamydia pneumoniae infection induces an unstable atherosclerotic plaque phenotype in LDL-receptor, ApoE double knockout mice.
Chlamydia pneumoniae infection of microglial cells in vitro: a model of microbial infection for neurological disease.
Chlamydia trachomatis enhances the expression of matrix metalloproteinases in an in vitro model of the human fallopian tube infection.
Circulating levels of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases during Japanese encephalitis virus infection.
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.
Collagenolytic enzymes (gelatinases) and their inhibitors in human amniochorionic membrane.
Colonic Expression of Genes Encoding Inflammatory Mediators and Gelatinases During Campylobacter Jejuni Infection of Conventional Infant Mice.
Comparative study for the presence of enterococcal virulence factors gelatinase, hemolysin and biofilm among clinical and commensal isolates of enterococcus faecalis.
Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis.
Cryptococcus neoformans pulmonary granuloma formation is associated with matrix metalloproteinase-2 expression.
Cytomegalovirus-caused release of collagenase IV from human cerebral microvascular endothelial cells.
Design, synthesis and anti-HIV-1 evaluation of hydrazide-based peptidomimetics as selective gelatinase inhibitors.
Detection of Enterococcus faecalis in subgingival biofilms of healthy, gingivitis, and chronic periodontitis subjects.
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Didanosine (ddI) associates with increased liver fibrosis in adult HIV-HCV coinfected patients.
Difference in Host Immune response to Methicillin-Resistant and Methicillin Sensitive Staphylococcus aureus (MRSA and MSSA) Endophthalmitis.
Different responses in MMPs/TIMPs expression of U937 and HepG2 cells to dengue virus infection.
Differential expression of hepatic fibrosis mediators in sick and spontaneously recovered mice with experimental biliary atresia.
Differential secretion of matrix metalloproteinase-2 and -9 after selective infection with group B streptococci in human fetal membranes.
Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2.
Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking.
Early prediction of urinary tract infection with urinary neutrophil gelatinase associated lipocalin.
Effect of adenovirus-mediated overexpression of decorin on metalloproteinases, tissue inhibitors of metalloproteinases and cytokines secretion by human gingival fibroblasts.
Effect of respiratory syncytial virus on the activity of matrix metalloproteinase in mice.
Efficiency of controlled topical delivery of silver sulfadiazine in infected burn wounds.
Efficient infection of mature skeletal muscle with herpes simplex virus vectors by using dextran sulfate as a co-receptor.
Enzymatic activity of Microsporum canis and Trichophyton mentagrophytes from breeding rabbits with and without skin lesions.
Enzymatically active Peptostreptococcus magnus: association with site of infection.
Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels.
Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection.
Expression of a progelatinase activator (MT1-MMP) in human fetal membranes.
Expression of matrix metalloproteinases in healthy and diseased human gingiva.
Expression of matrix metalloproteinases subsequent to urogenital Chlamydia muridarum infection of mice.
Functional characterization of a matrix metalloproteinase 2 gene in Litopenaeus vannamei.
GM-CSF- and TNF-{alpha}-mediated matrix metalloproteinase production by human osteoblasts and monocytes upon infection with Brucella abortus.
Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways.
High expression of protein phosphatase 4 is associated with the aggressive malignant behavior of colorectal carcinoma.
High fat diet modulates inflammatory parameters in the heart and liver during acute Trypanosoma cruzi infection.
HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes.
Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines.
Human Neutrophil Granule Exocytosis in Response to Mycobacterium smegmatis.
Identification of matrix metalloproteinase-9 in amniotic fluid and amniochorion in spontaneous labor and after experimental intrauterine infection or interleukin-1 beta infusion in pregnant rhesus monkeys.
Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
Immunohistochemical analysis of MMP-9, MMP-2 and TIMP-1, TIMP-2 expression in the central nervous system following infection with viral and bacterial meningitis.
In vivo assessment of growth and virulence gene expression during commensal and pathogenic lifestyles of luxABCDE-tagged Enterococcus faecalis strains in murine gastrointestinal and intravenous infection models.
Incidence of hemolysin, gelatinase, and aggregation substance among enterococci isolated from patients with endocarditis and other infections and from feces of hospitalized and community-based persons.
Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection.
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Increased production of matrix metalloproteinases 1 and 3 by smooth muscle cells upon infection with Chlamydia pneumoniae.
Increased production of matrix metalloproteinases in Helicobacter pylori-associated human gastritis.
Increased urinary neutrophil gelatinase associated lipocalin in urinary tract infections and leukocyturia.
Increased urinary neutrophil gelatinase associated lipocalin levels in a rat model of upper urinary tract infection.
Induction of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs correlates with outcome of acute experimental pseudomonal keratitis.
Influence of persistent canine distemper virus infection on expression of RECK, matrix-metalloproteinases and their inhibitors in a canine macrophage/monocytic tumour cell line (DH82).
Integration of transcriptomic profile of SARS-CoV-2 infected normal human bronchial epithelial cells with metabolic and protein-protein interaction networks.
Involvement of matrix metalloproteinases and their inhibitors in Staphylococcus aureus chronically infected bovine mammary glands during active involution.
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases.
Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity.
Levels of Matrix Metalloproteinase-2 and -9 in the Cerebrospinal Fluid of Dogs with Visceral Leishmaniasis.
Levels of plasma matrix metalloproteinases (MMP-2 and MMP-9) in response to INTEGRA® dermal regeneration template implantation.
Levocetirizine inhibits rhinovirus-induced up-regulation of fibrogenic and angiogenic factors in nasal polyp fibroblasts.
Lymphoid tissue collagen deposition in HIV-infected patients correlates with the imbalance between matrix metalloproteinases and their inhibitors.
Matrix metalloproteinase 2 of grass carp Ctenopharyngodon idella (CiMMP2) is involved in the immune response against bacterial infection.
Matrix metalloproteinase-2 contributes to joint destruction in group B streptococcus-induced arthritis.
Matrix Metalloproteinase-2 Mediates Intestinal Immunopathogenesis in Campylobacter Jejuni-Infected Infant Mice.
Matrix metalloproteinase-9 amplifies the immune response to Pseudomonas aeruginosa corneal infection.
Matrix metalloproteinases and their tissue inhibitors in serum and cerebrospinal fluid of children with Japanese encephalitis virus infection.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in coxsackievirus-induced myocarditis.
Matrix metalloproteinases in the cervical mucus plug in relation to gestational age, plug compartment, and preterm labor.
Matrix Metalloproteinases Vary with Airway Microbiota Composition and Lung Function in Non-Cystic Fibrosis Bronchiectasis.
Matrix metaloproteinase-2 and placentary dysfunction development in pregnancy with perinatal infections
Metalloproteinases 2 and 9 Immunoexpression in Periapical Lesions from Primary Endodontic Infection: Possible Relationship with the Histopathological Diagnosis and the Presence of Pain.
MMP cellular responses to dengue virus infection-induced vascular leakage.
MMP-2 gene expression at mRNA level in HBV and HCV infected patients.
Modified Profile of Matrix Metalloproteinase 2 and 9 Production by Human Fallopian Tube Epithelial Cells After Infection In Vitro With Neisseria gonorrhoeae.
Molecular epidemiology of the fsr locus and of gelatinase production among different subsets of Enterococcus faecalis isolates.
Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways.
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Peculiarities of changes in indices of calcium and zinc trace elements and matrix metalloproteinase-2 in pregnant women with perinatal infections.
Potential Role of Fibroblast-Like Synoviocytes in Joint Damage Induced by Brucella abortus Infection through Production and Induction of Matrix Metalloproteinases.
Proteolytic activation of corneal matrix metalloproteinase by Pseudomonas aeruginosa elastase.
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Relationship between MMP Expression and Virulence of Dengue Virus Type-2 in Infected Mosquito and Mammalian Cells.
Relative expression of matrix metalloproteinase-2 and -9 in synovial fluid from healthy calves and calves with experimentally induced septic arthritis.
Rhinovirus upregulates matrix metalloproteinase-2, matrix metalloproteinase-9, and vascular endothelial growth factor expression in nasal polyp fibroblasts.
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
Serological cytokine profiles of cardiac rejection and lung infection after heart transplantation in rats.
Serum levels of matrix metalloproteinase-2, -9, and vitamin D in patients with multiple sclerosis with or without herpesvirus-6 seropositivity.
Sialic acid removal by trans-sialidase modulates MMP-2 activity during Trypanosoma cruzi infection.
Staphylococcus aureus Biofilm Infection Compromises Wound Healing by Causing Deficiencies in Granulation Tissue Collagen.
Staphylococcus aureus increases cytokine and matrix metalloproteinase expression in nasal mucosae of patients with chronic rhinosinusitis and nasal polyps.
Strong biofilm production, antibiotic multi-resistance and high gelE expression in epidemic clones of Enterococcus faecalis from orthopaedic implant infections.
Study of biological characteristics of Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis and from patients with extra-pulmonary infections.
Synergic and antagonistic relationship between MMP-2 and MMP-9 with fibrosis and inflammation in Chagas' cardiomyopathy.
The effect of Candida albicans systemic infection on matrix metalloproteinases in breast cancer bearing BALB/c mice.
The Intraperitoneal Transcriptome of the Opportunistic Pathogen Enterococcus faecalis in Mice.
The risk of relapses in multiple sclerosis during systemic infections.
The Role of Gelatinases in Campylobacter Jejuni Infection of Gnotobiotic Mice.
The role of metalloproteases in Leishmania species infection in the New World: a systematic review.
The use of pentoxifylline as adjuvant therapy with praziquantel downregulates profibrogenic cytokines, collagen deposition and oxidative stress in experimental schistosomiasis mansoni.
Therapeutical effects of vaccine from Trypanosoma cruzi amastigote surface protein 2 by simultaneous inoculation with live parasites.
TIMP-2 expression modulates human melanoma cell adhesion and motility.
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Treponema denticola upregulates MMP-2 activation in periodontal ligament cells: interplay between epigenetics and periodontal infection.
Upregulation of extracellular matrix metalloproteinase inducer (EMMPRIN) and gelatinases in human atherosclerosis infected with Chlamydia pneumoniae: the potential role of Chlamydia pneumoniae infection in the progression of atherosclerosis.
Ureaplasma Urealyticum Infection Contributes to the Development of Pelvic Endometriosis Through Toll-Like Receptor 2.
Urinary Neutrophil Gelatinase Associated Lipocalin - A Sensitive Marker for Urinary Tract Infection in Children.
Zymographic analysis of latent and activated forms of matrix metalloproteinase-2 and -9 in synovial fluid: correlation to polymorphonuclear leukocyte infiltration and in response to infection.
[Effect of cytomegalovirus infection on expression of matrix metalloproteinase-2 in human endothelial cells.]
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
[Therapeutic effect of Haobieyangyinruanjianfang on the mouse liver fibrosis caused by schistosomiasis]
[Virulence genes and bacteriocins in Enterococcus faecalis strains isolated from different clinical samples in Maule Region, Chile].
Inferior Wall Myocardial Infarction
Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.
Infertility
Altered expression of genes involved in the production and degradation of endometrial extracellular matrix in patients with unexplained infertility and recurrent miscarriages.
Endometrial mRNA expression of matrix metalloproteinases, their tissue inhibitors and cell adhesion molecules in unexplained infertility and implantation failure patients.
Matrix metalloproteinase 2 is associated with changes in steroid hormones in the sera and peritoneal fluid of patients with endometriosis.
Infertility, Male
MMP2, MMP9 and TIMP2 polymorphisms affect sperm parameters but not fertility in Polish males.
Inflammatory Bowel Diseases
Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential?
Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases.
Fecal Neutrophil Gelatinase Associated Lipocalin (NGAL) as a biomarker for Inflammatory Bowel Disease.
Gelatinase A (MMP-2), collagenase-2 (MMP-8), and laminin-5 gamma2-chain expression in murine inflammatory bowel disease (ulcerative colitis).
Identification of Matrix Metalloproteinase-2 and -9 Activities within Intestinal Mucosa of Clinically Healthy Beagle Dogs.
Identification of matrix metalloproteinase-2 and -9 activities within the intestinal mucosa of dogs with chronic enteropathies.
Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease.
Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases.
Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis.
Selective gelatinase blockage ameliorates acute DSS colitis.
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.
Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels.
Unlocking the Gates to Inflammatory Bowel Disease: The Role of Enterococcus faecalis Gelatinase.
Inflammatory Breast Neoplasms
Membrane type-1 matrix metalloproteinase (MT1-MMP) correlates with the expression and activation of matrix metalloproteinase-2 (MMP-2) in inflammatory breast cancer.
Influenza, Human
Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice.
Influenza A virus infection modulates the expression of type IV collagenase in epithelial cells.
Role of matrix metalloproteinases and their inhibitor in the development of early pulmonary fibrosis in mice infected with influenza A/H5N1 A/goose/Krasnoozerskoye/627/05 virus.
Insulin Resistance
Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension.
Defining the Regulated Secreted Proteome of Rodent Adipocytes upon the Induction of Insulin Resistance.
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients.
Exercise ameliorates serum MMP-9 and TIMP-2 levels in patients with type 2 diabetes.
Lipocalin-2 inhibits autophagy and induces insulin resistance in H9c2 cells.
Resistance training and caloric restriction prevent systolic blood pressure rise by improving the nitric oxide effect on smooth muscle and morphological changes in the aorta of ovariectomized rats.
Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet.
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors in women with glucose intolerance in pregnancy and normal controls.
Sexually Dimorphic Diet-Induced Insulin Resistance in Obese Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)-Deficient Mice.
The skin remodeling in type 1 diabetes and insulin resistance animal models.
Intervertebral Disc Degeneration
Alterations in biochemical components of extracellular matrix in intervertebral disc herniation: role of MMP-2 and TIMP-2 in type II collagen loss.
Analysis of genetic polymorphisms associated with intervertebral disc degeneration.
Association of the polymorphism of MMP2 with the risk and severity of lumbar disc degeneration in the Chinese Han population.
Circular RNA derived from TIMP2 functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR?185?5p and matrix metalloproteinase 2.
Degenerative Cervical Myelopathy: Epidemiology, Genetics, and Pathogenesis.
Increased MMP-2 activity during intervertebral disc degeneration is correlated to MMP-14 levels.
Induction of matrix metalloproteinase-2 and -3 activity in ovine nucleus pulposus cells grown in three-dimensional agarose gel culture by interleukin-1beta: a potential pathway of disc degeneration.
MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc.
[Effect of Acupotomy Lysis at Cervical Acupoints on Expression of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinase 1 and Changes of Pulpiform Nucleus Ultrastructure in Rats with Degenerated Cervical Intervertebral Discs].
[Expression of hypoxia-inducible factor-1alpha and matrix metalloproteinase-2 in degenerative lumbar intervertebral disc]
Intervertebral Disc Displacement
Alterations in biochemical components of extracellular matrix in intervertebral disc herniation: role of MMP-2 and TIMP-2 in type II collagen loss.
Altered expression of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in cervical disc herniation patients.
Analysis of genetic polymorphisms associated with intervertebral disc degeneration.
Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients.
The impact of changes in serum levels of metalloproteinase-2 and metalloproteinase-9 on pain perception in patients with disc herniation before and after surgery.
The increased expression of matrix metalloproteinases associated with elastin degradation and fibrosis of the ligamentum flavum in patients with lumbar spinal stenosis.
Intracranial Aneurysm
Association of functional MMP-2 gene variant with intracranial aneurysms: case-control genetic association study and meta-analysis.
Correlation between MMP-2 and NF-? B expression of intracranial aneurysm.
Effect of dietary ? carotene on cerebral aneurysm and subarachnoid haemorrhage in the brain apo E(-/-) mice.
Elastase-induced intracranial aneurysms in hypertensive mice.
Gelatinase activity and the occurrence of cerebral aneurysms.
Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2.
Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats.
Matrix metalloproteinase-9 in cerebral aneurysms.
Matrix metalloproteinases 2 and 9 in human atherosclerotic and non-atherosclerotic cerebral aneurysms.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases expression in human cerebral ruptured and unruptured aneurysm.
miR-34a regulates phenotypic modulation of vascular smooth muscle cells in intracranial aneurysm by targeting CXCR3 and MMP-2.
The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients.
The role of MMP-2 and MMP-9 polymorphisms in sporadic intracranial aneurysms.
[In situ localization of mRNA gelatinases in cerebral aneurysms]
Intracranial Arteriosclerosis
Biomarkers and location of atherosclerosis: Matrix metalloproteinase-2 may be related to intracranial atherosclerosis.
Intracranial Hemorrhages
Association between expression of MMP-2 and MMP-9 genes and pathogenesis of intracranial hemorrhage in severe coagulation factor XIII deficiency.
Clinical efficacy of mouse nerve growth factor plus nimodipine in neonatal intracranial hemorrhage and its effect on plasma PAF, CNP, MMP-2, and neurological function.
Expression and CpG island methylation pattern of MMP-2 and MMP-9 genes in patients with congenital factor XIII deficiency and intracranial hemorrhage.
[Study on expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in brain tissue adjacent to hemorrhage after brain hemorrhage in human]
Ischemic Attack, Transient
Effect of Propofol Post-treatment on Blood-Brain Barrier Integrity and Cerebral Edema After Transient Cerebral Ischemia in Rats.
Ischemic Stroke
A gelatin in situ-overlay technique localizes brain matrix metalloproteinase activity in experimental focal cerebral ischemia.
Association between microRNA binding site polymorphisms in immunoinflammatory genes and recurrence risk of ischemic stroke.
Cerebral mast cells mediate blood-brain barrier disruption in acute experimental ischemic stroke through perivascular gelatinase activation.
Complexity in differentiating truncated or matured forms of MMP-2 and MMP-9 by zymography in acute ischemic stroke induced rat brain tissues.
Correlation between matrix metalloproteinase-2 polymorphisms and first and recurrent atherosclerotic ischemic stroke events: a case-control study.
Decreased plasma decorin levels following acute ischemic stroke: correlation with MMP-2 and differential expression in TOAST subtypes.
Different expression of ubiquitin C-terminal hydrolase-L1 and ?II-spectrin in ischemic and hemorrhagic stroke: Potential biomarkers in diagnosis.
Different roles of matrix metalloproteinases-2 and -9 after human ischaemic stroke.
Discovery of 7-aminophenanthridin-6-one as a new scaffold for matrix metalloproteinase inhibitors with multitarget neuroprotective activity.
Do extracellular-matrix-regulating enzymes play a role in cervical artery dissection?
Early upregulation of matrix metalloproteinases following reperfusion triggers neuroinflammatory mediators in brain ischemia in rat.
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
Effects of Mesenchymal Stem Cell Treatment on the Expression of Matrix Metalloproteinases and Angiogenesis during Ischemic Stroke Recovery.
Influence of interleukin-1 beta gene polymorphisms on the risk of myocardial infarction and ischemic stroke at young age in vivo and in vitro.
Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons.
Intraplaque MMP-8 levels are increased in asymptomatic patients with carotid plaque progression on ultrasound.
Matrix metalloproteinase-2 gene polymorphisms are associated with ischemic stroke in a Hainan population.
Methylation in the matrix metalloproteinase-2 gene is associated with cerebral ischemic stroke.
Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke.
Profiles of matrix metalloproteinases, their inhibitors, and laminin in stroke patients: influence of different therapies.
White Matter Hyperintensity Volume Correlates with Matrix Metalloproteinase-2 in Acute Ischemic Stroke.
Jaw Cysts
Identification and characterization of gelatinases/type IV collagenases in jaw cysts.
Joint Diseases
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism.
A novel mutation in the matrix metallopeptidase 2 coding gene associated with intrafamilial variability of multicentric osteolysis, nodulosis, and arthropathy.
Al-Aqeel Sewairi syndrome, a new autosomal recessive disorder with multicentric osteolysis, nodulosis and arthropathy. The first genetic defect of matrix metalloproteinase 2 gene.
Bisphosphonates in multicentric osteolysis, nodulosis and arthropathy (MONA) spectrum disorder - an alternative therapeutic approach.
Characterisation of the cell type-specificity of collagenase 3 mRNA expression in comparison with membrane type 1 matrix metalloproteinase and gelatinase A in the synovial membrane in rheumatoid arthritis.
Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children.
Degradative enzymes in osteoarthritis.
Determination of MMP-2 and -9 activities in synovial fluid of horses with osteoarthritic and arthritic joint diseases using gelatin zymography and immunocapture activity assays.
Loss of MMP-2 in osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis.
Matrix metalloproteinase, vitamin A and methylprednisolone effects on experimentally induced amyloid arthropathy.
Matrix metalloproteinase-2 and -9 are activated in joint diseases.
Matrix metalloproteinases 2 and 9 activity in bovine synovial fluids.
Matrix metalloproteinases 2 and 9 in equine synovial fluids.
Measurement of cartilage oligomeric matrix protein (COMP) in normal and diseased equine synovial fluids.
Multicentric osteolysis with nodulosis and arthropathy (MONA) with cardiac malformation, mimicking polyarticular juvenile idiopathic arthritis: case report and literature review.
Multicentric Osteolysis, Nodulosis, and Arthropathy in two unrelated children with matrix metalloproteinase 2 variants: Genetic-skeletal correlations.
Synovial fluid gelatinase concentrations and matrix metalloproteinase and cytokine expression in naturally occurring joint disease in horses.
The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis.
Torg-Winchester syndrome: lack of efficacy of pamidronate therapy.
Keloid
Efficacy and possible mechanisms of Botulinum Toxin type A on hypertrophic scarring.
Gelatinase activity in keloids and hypertrophic scars.
Ginseng as a Potential Novel Addition to the Antikeloid Weaponry.
High-mobility Group Box Protein-1, Matrix Metalloproteinases, and Vitamin D in Keloids and Hypertrophic Scars.
Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration.
Matrix metalloproteinase-2 and -9 activities in human keloids, hypertrophic and atrophic scars: a pilot study.
Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: implications for mechanisms of keloid progression.
TGF-beta1 antisense therapy modulates expression of matrix metalloproteinases in keloid-derived fibroblasts.
Tissue Inhibitor of Metalloproteinase-2 Suppresses Collagen Synthesis in Cultured Keloid Fibroblasts.
Keratitis
Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis.
Detection of virulence factors in Serratia strains isolated from contact lens-associated corneal ulcers.
Evaluation of matrix metalloproteinase concentrations in precorneal tear film from dogs with Pseudomonas aeruginosa-associated keratitis.
Immunohistochemical study of matrix metalloproteinases-2 and -9, macrophage inflammatory protein-2 and tissue inhibitors of matrix metalloproteinases-1 and -2 in normal, purulonecrotic and fungal infected equine corneas.
JAK/STAT regulation of Aspergillus fumigatus corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity.
Modulation of Corneal FAK/PI3K/Akt Signaling Expression and of Metalloproteinase-2 and Metalloproteinase-9 during the Development of Herpes Simplex Keratitis.
Testican-1 Promotes Resistance against Pseudomonas aeruginosa-Induced Keratitis through Regulation of MMP-2 Expression and Activation.
Keratitis, Herpetic
Active form of gelatinases in tear fluidin patients with corneal ulcer or ocular burn.
Modulation of Corneal FAK/PI3K/Akt Signaling Expression and of Metalloproteinase-2 and Metalloproteinase-9 during the Development of Herpes Simplex Keratitis.
Keratoacanthoma
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas.
Keratoconjunctivitis
Metalloproteinases in canine experimental traumatic keratoconjunctivitis.
Keratoconus
Altered gelatinolytic activities in an apparent unilateral keratoconus patient. A case report.
Altered type VI collagen synthesis by keratoconus keratocytes in vitro.
Characterization of a human corneal metalloproteinase inhibitor (TIMP-1).
Collagenolytic proteinases in keratoconus.
Elements of the nitric oxide pathway can degrade TIMP-1 and increase gelatinase activity.
Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in normal and keratoconus corneas.
Increased collagenase and gelatinase activities in keratoconus.
Increased gelatinolytic activity in keratoconus keratocyte cultures. A correlation to an altered matrix metalloproteinase-2/tissue inhibitor of metalloproteinase ratio.
Is the corneal degradation in keratoconus caused by matrix-metalloproteinases?
Keratoconus: Matrix metalloproteinase-2 activation and TIMP modulation.
Matrix metalloproteinase 2: involvement in keratoconus.
Over-expression of a gelatinase A activity in keratoconus.
The expression of human corneal MMP-2, MMP-9, proMMP-13 and TIMP-1 in bullous keratopathy and keratoconus.
The Relation Between Keratoconus and Plasma Levels of MMP-2, Zinc, and SOD.
Keratosis, Actinic
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Expression of Gelatinases (MMP-2, MMP-9) and Gelatinase Activator (MMP-14) in Actinic Keratosis and in In Situ and Invasive Squamous Cell Carcinoma.
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Kidney Diseases
Exploration of association of 1,25-OH2D3 with augmentation index, a composite measure of arterial stiffness.
In Diabetic Kidney Disease Urinary Exosomes Better Represent Kidney Specific Protein Alterations Than Whole Urine.
Intraoperative venous congestion and acute kidney injury in cardiac surgery: an observational cohort study.
Progression of kidney disease in non-diabetic patients with coronary artery disease: predictive role of circulating matrix metalloproteinase-2, -3, and -9.
[Role of matrix metalloproteinases in the progression of renal lesions]
Kidney Diseases, Cystic
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.
Kidney Failure, Chronic
Association of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 With Endothelial Dysfunction, Cardiovascular Disease Risk Factors and thrombotic events in Children With End-stage Renal Disease.
Effluent Tenascin-C Levels Reflect Peritoneal Deterioration in Peritoneal Dialysis: MAJOR IN PD Study.
Investigation of the Relationship Between IL-18 (-?607 C/A), IL-18 (-?137 G/C), and MMP-2 (-?1306 C/T) Gene Variations and Serum Copper and Zinc Levels in Patients Diagnosed with Chronic Renal Failure.
Matrix Metalloproteinase (MMP)-2 Genetic Variants Modify the Circulating MMP-2 Levels in End-Stage Kidney Disease.
Regulation of miR-29b and miR-30c by vitamin D receptor activators contributes to attenuate uraemia-induced cardiac fibrosis.
Serum matrix metalloproteinases MMP-2 and MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in diabetic nephropathy.
Urinary neutrophil gelatinase associated lipocalin as a biomarker in ifosfamide induced chronic renal failure.
Kidney Neoplasms
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Antitumor activity of irradiated riboflavin on human renal carcinoma cell line 786-O.
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Influence of osteopontin short hairpin RNA on the proliferation and invasion of human renal cancer cells.
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
RNA interference suppression of A100A4 reduces the growth and metastatic phenotype of human renal cancer cells via NF-kB-dependent MMP-2 and bcl-2 pathway.
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
Klatskin Tumor
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study.
Krukenberg Tumor
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Labyrinth Diseases
Expression of the recessive glomerulosclerosis gene Mpv17 regulates MMP-2 expression in fibroblasts, the kidney, and the inner ear of mice.
Laryngeal Neoplasms
A combined modality of carboplatin and photodynamic therapy suppresses epithelial-mesenchymal transition and matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in HEp-2 human laryngeal cancer cells via ROS-mediated inhibition of MEK/ERK signalling pathway.
Activity of matrix metalloproteinases-2 and -9 in advanced laryngeal cancer.
Expression of type IV collagen and matrix metalloproteinase-2 (type IV collagenase) in relation to nodal status in laryngeal cancer.
Matrix metalloproteinase 2 (MMP2) protein expression and laryngeal cancer prognosis: a meta analysis.
Matrix metalloproteinases (MMPs) and inhibitor of metalloproteinases (TIMP) mRNA and protein expression in laryngeal squamous cell carcinoma.
MMP-2 expression in 102 patients with glottic laryngeal cancer.
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
SOX2 promotes the migration and invasion of laryngeal cancer cells by induction of MMP-2 via the PI3K/Akt/mTOR pathway.
[Role of siRNA mediated matrix metalloproteinase-2 gene silencing in the inhibition of invasion and growth of laryngeal cancer cells]
[The experimental investigation of the invasion and growth of laryngeal cancer by matrix metalloproteinase-2 and matrix metalloproteinase-9 gene silence together]
Laryngitis
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
Leg Ulcer
Ectopic localization of matrix metalloproteinase-9 in chronic cutaneous wounds.
Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration.
Elevated expression of extracellular matrix metalloproteinase inducer (CD147) and membrane-type matrix metalloproteinases in venous leg ulcers.
Matrix metalloproteinases, gelatinase and collagenase, in chronic leg ulcers.
Mitogenic bovine whey extract modulates matrix metalloproteinase-2, -9, and tissue inhibitor of matrix metalloproteinase-2 levels in chronic leg ulcers.
The direct inhibition of MMP-2 and MMP-9 by an enzyme alginogel: a possible mechanism of healing support for venous leg ulcers.
The Impact of Differential Expression of Extracellular Matrix Metalloproteinase Inducer, Matrix Metalloproteinase-2, Tissue Inhibitor of Matrix Metalloproteinase-2 and PDGF-AA on the Chronicity of Venous Leg Ulcers.
The role of the urokinase-type plasminogen activator (uPA) and its receptor (CD87) in lipodermatosclerosis.
Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9.
Leiomyoma
Activity of matrix metalloproteinase-2 and -9 and contents of their tissue inhibitors in uterine leiomyoma and corresponding myometrium.
Differential effects of tumor necrosis factor-? on matrix metalloproteinase-2 expression in human myometrial and uterine leiomyoma smooth muscle cells.
Differential expression of matrix metalloproteinases and their tissue inhibitors in leiomyomata: a mechanism for gonadotrophin releasing hormone agonist-induced tumour regression.
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Expression of vascular endothelial factor-A, gelatinases (MMP-2, MMP-9) and TIMP-1 in uterine leiomyomas.
Lichong decoction reduces Matrix Metalloproteinases-2 expression but increases Tissue Inhibitors of Matrix Metalloproteinases-2 expression in a rat model of uterine leiomyoma.
Mechanism of collagen biosynthesis up-regulation in cultured leiomyoma cells.
MicroRNA 21a-5p overexpression impacts mediators of extracellular matrix formation in uterine leiomyoma.
Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells.
Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells.
[The expression of MMP-2, -9 in the uterine leiomyoma and its significance in prognosis].
Leiomyosarcoma
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
MMP-1 and MMP-2 expression in uterine leiomyosarcoma and correlation with different clinicopathologic parameters.
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Leishmaniasis
Canine cerebral leishmaniasis: Potential role of matrix metalloproteinase-2 in the development of neurological disease.
Leishmaniasis, Cutaneous
Therapeutic failure in American cutaneous leishmaniasis is associated with gelatinase activity and cytokine expression.
Leishmaniasis, Visceral
Canine cerebral leishmaniasis: Potential role of matrix metalloproteinase-2 in the development of neurological disease.
Differential alterations in the activity of matrix metalloproteinases within the nervous tissue of dogs in distinct manifestations of visceral leishmaniasis.
Expression of matrix metalloproteinase-2 and metalloproteinase-9 in the skin of dogs with visceral leishmaniasis.
Levels of Matrix Metalloproteinase-2 and -9 in the Cerebrospinal Fluid of Dogs with Visceral Leishmaniasis.
Lentivirus Infections
LncRNA-HCG18 regulates the viability, apoptosis, migration, invasion and epithelial-mesenchymal transition of papillary thyroid cancer cells via regulating the miR-106a-5p/PPP2R2A axis.
Potential suppression of the high glucose and insulin-induced retinal neovascularization by Sirtuin 3 in the human retinal endothelial cells.
Leprosy
Expression of metalloproteinases (MMP-2, MMP-9, and TACE) and TNF-alpha in the nerves of leprosy patients.
Leptospirosis
Neutrophil Gelatinase Associated Lipocalin (NGAL) in Leptospirosis Acute Kidney Injury: A Multicenter Study in Thailand.
Leukemia
A possible role of 92 kDa type IV collagenase in the extramedullary tumor formation in leukemia.
Activation of collagenase IV gene expression and enzymatic activity by the Moloney murine leukemia virus long terminal repeat.
Amsacrine suppresses matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in human leukemia cells.
Association of Matrix Metallopeptidase-2 Promoter Polymorphisms With the Risk of Childhood Leukemia.
Autocrine regulation of matrix metalloproteinase-9 gene expression and secretion by tumor necrosis factor-alpha (TNF-alpha) in NB4 leukemic cells: specific involvement of TNF receptor type 1.
Caffeine induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in human leukemia U937 cells via Ca(2+)/ROS-mediated suppression of ERK/c-fos pathway and activation of p38 MAPK/c-jun pathway.
CIL-102 induces matrix metalloproteinase-2 (MMP-2)/MMP-9 down-regulation via simultaneous suppression of genetic transcription and mRNA stability.
Effects of AG490 and S3I-201 on regulation of the JAK/STAT3 signaling pathway in relation to angiogenesis in TRAIL-resistant prostate cancer cells in vitro.
Effects of myokines on bone.
Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.
Freshly isolated osteoarthritic chondrocytes are catabolically more active than normal chondrocytes, but less responsive to catabolic stimulation with interleukin-1beta.
Gallic acid downregulates matrix metalloproteinase-2 (MMP-2) and MMP-9 in human leukemia cells with expressed Bcr/Abl.
High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis.
Is dual inhibition of metalloenzymes HDAC-8 and MMP-2 a potential pharmacological target to combat hematological malignancies?
Leukemic cells (HL-60) produce a novel extracellular matrix-degrading proteinase that is not inhibited by tissue inhibitors of matrix metalloproteinases (TIMPs).
Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins.
MMP-2 and MMP-9 expression in adult and childhood acute lymphatic leukemia (ALL).
Mutations that abrogate transactivational activity of the feline leukemia virus long terminal repeat do not affect virus replication.
No correlation between pinopode formation and LIF and MMP2 expression in endometrium during implantation window.
Overexpression of amyloid precursor protein in acute myeloid leukemia enhances extramedullary infiltration by MMP-2.
Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells.
Procyanidin oligomers from Japanese quince (Chaenomeles japonica) fruit inhibit activity of MMP-2 and MMP-9 metalloproteinases.
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells.
Simvastatin induces NF?B/p65 down-regulation and JNK1/c-Jun/ATF-2 activation, leading to matrix metalloproteinase-9 (MMP-9) but not MMP-2 down-regulation in human leukemia cells.
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
The essential roles of matrix metalloproteinase-2, membrane type 1 metalloproteinase and tissue inhibitor of metalloproteinase-2 in the invasive capacity of acute monocytic leukemia SHI-1 cells.
Tumor necrosis factor alpha and lymphotoxin stimulate human myeloblastic leukemia cell (ML-1) invasion through a reconstituted basement membrane (Matrigel) with concomitant induction of 92 kDa gelatinase secretion.
[Acetyl-11-keto-beta-boswellic acid and arsenic trioxide regulate the productions and activities of matrix metalloproteinases in human skin fibroblasts and human leukemia cell line THP-1].
[Effect of glycyrrhetinic acid on invasive capacity of leukemic cells and activity of gelatinase]
[Effect of TIMP-2, MT1-MMP and MMP-2 expression on the in vitro invasive capacity of acute monocytic leukemia SHI-1 cells.]
[Expression of gelatinase A and B in cord blood CD34+ cells and leukemic cell lines]
[Expression of nuclear factor-kappaB in bone marrow cells from patients with acute leukemia and its relationship with P21, MMP-2 and MMP-9]
[High tumorigenicity of human acute monocytic leukemic cell Line SHI-1 in nude mice and its mechanism]
[Inhibition effect of short hairpin RNA on VEGF receptor flt-1 gene expression in leukemia cell line k562]
Leukemia, B-Cell
Pleomorphic liposarcoma: Clinical observations and molecular variables.
Leukemia, Erythroblastic, Acute
[Regulation of Ruxolitinib on matrix metalloproteinase in JAK2V617F positive myeloroliferative neoplasms cells].
Leukemia, Feline
Feline leukemia virus long terminal repeat activates collagenase IV gene expression through AP-1.
Long terminal repeat regions from exogenous but not endogenous feline leukemia viruses transactivate cellular gene expression.
Mutations that abrogate transactivational activity of the feline leukemia virus long terminal repeat do not affect virus replication.
Leukemia, Lymphocytic, Chronic, B-Cell
A catalytically inactive gelatinase B/MMP-9 mutant impairs homing of chronic lymphocytic leukemia cells by altering migration regulatory pathways.
Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
Leukemia, Monocytic, Acute
The essential roles of matrix metalloproteinase-2, membrane type 1 metalloproteinase and tissue inhibitor of metalloproteinase-2 in the invasive capacity of acute monocytic leukemia SHI-1 cells.
[Acetyl-11-keto-beta-boswellic acid and arsenic trioxide regulate the productions and activities of matrix metalloproteinases in human skin fibroblasts and human leukemia cell line THP-1].
[Effect of TIMP-2, MT1-MMP and MMP-2 expression on the in vitro invasive capacity of acute monocytic leukemia SHI-1 cells.]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
A pentanoic acid derivative targeting matrix metalloproteinase-2 (MMP-2) induces apoptosis in a chronic myeloid leukemia cell line.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties.
Leukemia, Myeloid
A possible role of 92 kDa type IV collagenase in the extramedullary tumor formation in leukemia.
All-Trans Retinoic Acid Enhances Matrix Metalloproteinase 2 Expression and Secretion in Human Myeloid Leukemia THP-1 Cells.
Characteristics of 92 kDa type IV collagenase/gelatinase produced by granulocytic leukemia cells: structure, expression of cDNA in E. coli and enzymic properties.
Correlation in the expression of type IV collagenase and the invasive and chemotactic abilities of myelomonocytic cells during differentiation into macrophages.
Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells.
Leukemia, Myeloid, Acute
Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.
Expression of the active form of MMP-2 on the surface of leukemic cells accounts for their in vitro invasion.
Matrix Metalloproteinases in the Hematopoietic Microenvironment.
Overexpression of amyloid precursor protein in acute myeloid leukemia enhances extramedullary infiltration by MMP-2.
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
The Hematopoietic Microenvironment: Matrix Metalloproteinases in the Hematopoietic Microenvironment.
[Activity of matrix metalloproteinases MMP-2 and MMP-9 in bone marrow plasma of patients with acute myeloid leukemia].
[Relationship between VEGF and MMP-2, MMP-9 in 82 Patients with Acute Myeloid Leukemia.]
Leukemia, Promyelocytic, Acute
Autocrine regulation of matrix metalloproteinase-9 gene expression and secretion by tumor necrosis factor-alpha (TNF-alpha) in NB4 leukemic cells: specific involvement of TNF receptor type 1.
Leukocytosis
Neutrophil gelatinase B and chemokines in leukocytosis and stem cell mobilization.
Leukoplakia
Matrix metalloproteinase-2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: immunohistochemistry and RT-PCR analysis.
Leukoplakia, Oral
Changes in the expression of Col IV, gelatinase and TIMP-1 in oral leukoplakia.
Matrix metalloproteinase-2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: immunohistochemistry and RT-PCR analysis.
Lichen Planus
Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis.
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus.
Lichen Planus, Oral
Correlation of VEGF and MMP-2 levels in oral lichen planus: An in vivo immunohistochemical study.
Immunohistochemical and clinical significance of matrix metalloproteinase-2 and its inhibitor in oral lichen planus.
miR-125b inhibits keratinocyte proliferation and promotes keratinocyte apoptosis in oral lichen planus by targeting MMP-2 expression through PI3K/Akt/mTOR pathway.
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus.
Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus]
Lichen Sclerosus et Atrophicus
A comparative study of MMP-2 in vulvar neoplasms.
Lipodystrophy
Didanosine (ddI) associates with increased liver fibrosis in adult HIV-HCV coinfected patients.
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Liposarcoma
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
Liver Cirrhosis
Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells.
Activity of MMP-2, MMP-8 and MMP-9 in serum as a marker of progression of alcoholic liver disease in people from Lublin Region, eastern Poland.
Adenoviral delivery of dominant-negative transforming growth factor beta type II receptor up-regulates transcriptional repressor SKI-like oncogene, decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats.
Aldose reductase is involved in the development of murine diet-induced nonalcoholic steatohepatitis.
An herbal formula, CGX, exerts hepatotherapeutic effects on dimethylnitrosamine-induced chronic liver injury model in rats.
Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats.
Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice.
Circulating matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as serum markers of fibrosis in patients with chronic hepatitis C. Relationship to interferon response.
Clinical implication of vascular cell adhesion molecule-1 and very late activation antigen-4 interaction, and matrix metalloproteinase-2 production in patients with liver disease.
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Clinical utility of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 concentrations in the assessment of liver fibrosis due to chronic hepatitis B.
Combined use of aspartate aminotransferase, platelet count and matrix metalloproteinase 2 measurements to predict liver fibrosis in HIV/hepatitis C virus-coinfected patients.
Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet.
Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C.
Diagnostic potential of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as non-invasive markers of hepatic fibrosis in patients with HCV related chronic liver disease.
Disruption of tissue-type plasminogen activator gene in mice aggravated liver fibrosis.
Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers.
Dynamic change of cells expressing MMP-2 mRNA and MT1-MMP mRNA in the recovery from liver fibrosis in the rat.
Effect of antiviral therapy on markers of fibrogenesis in patients with chronic hepatitis C.
Effects of alcohol consumption on eight circulating markers of liver fibrosis.
Enhanced efficacy of curcumin with phosphatidylserine-decorated nanoparticles in the treatment of hepatic fibrosis.
Evaluation of matrix metalloproteinases and their endogenous tissue inhibitors in biliary atresia-associated liver fibrosis.
Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis.
Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis.
Fraxinus rhynchophylla ethanol extract attenuates carbon tetrachloride-induced liver fibrosis in rats via down-regulating the expressions of uPA, MMP-2, MMP-9 and TIMP-1.
Heparanase expression during normal liver development and following partial hepatectomy.
HIF-1 ? as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats.
Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/?-Catenin Reduces Liver Fibrosis in Mice.
Inhibition of liver fibrosis using vitamin A-coupled liposomes to deliver matrix metalloproteinase-2 siRNA in vitro.
Liver fibrosis improvement in chronic hepatitis C after direct acting-antivirals is accompanied by reduced profibrogenic biomarkers-a role for MMP-9/TIMP-1.
Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression.
Matrilysin (MMP-7) is a major matrix metalloproteinase upregulated in biliary atresia-associated liver fibrosis.
Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients.
Matrix Metalloproteinase-13 Promotes Recovery from Experimental Liver Cirrhosis in Rats.
Matrix metalloproteinase-2 activation in human hepatic fibrosis regulation by cell-matrix interactions.
Matrix Metalloproteinases (MMPs) Activity in Cultured Canine Bone Marrow Stromal Cells (BMSCs).
Matrix metalloproteinases and their tissue inhibitors in children with chronic hepatitis B treated with lamivudine.
MMP mediated degradation of type VI collagen is highly associated with liver fibrosis--identification and validation of a novel biochemical marker assay.
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in rats.
Naringenin loaded multifunctional nanoparticles to enhance the chemotherapeutic efficacy in hepatic fibrosis.
Neutrophil Gelatinase Associated Lipocalin (NGAL) - a biomarker of renal dysfunction in patients with liver cirrhosis: Do we have enough proof?
Noninvasive diagnosis of fibrosis in chronic liver disease.
Plasma levels of matrix metalloproteinase-2 and -9 in male and female patients with cirrhosis of different aetiologies.
PM2.5 induces liver fibrosis via triggering ROS-mediated mitophagy.
Production of pro- and anti-fibrotic agents by rat Kupffer cells; the effect of octreotide.
Resolution of liver fibrosis by isoquinoline alkaloid berberine in CCl?-intoxicated mice is mediated by suppression of oxidative stress and upregulation of MMP-2 expression.
Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases.
The anti-fibrotic effect of pirfenidone in rat liver fibrosis is mediated by downregulation of procollagen alpha1(I), TIMP-1 and MMP-2.
The Clinical Significance of Serum Apoptotic Cytokeratin 18 Neoepitope M30 (CK-18 M30) and Matrix Metalloproteinase 2 (MMP-2) Levels in Chronic Hepatitis B Patients with Cirrhosis.
The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells.
The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation.
The use of low molecular weight heparin-pluronic nanogels to impede liver fibrosis by inhibition the TGF-?/Smad signaling pathway.
Usefulness of non-invasive markers for predicting liver cirrhosis in patients with chronic hepatitis B.
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
[Dynamic evolution of MMP-2 gene expression and its enzymatic activities in experimental liver fibrosis]
[Effect of high fat on fibrosis in rat hepatic stellate cells].
[Effect of oxymatrine on serum matrix metalloproteinase-2 and its inhibitor in patients with chronic hepatitis B and liver cirrhosis]
[Effect of TGFbeta1 vaccine on the expression of MMP-2 and TIMP-2 in rats with liver fibrosis.]
[Effects of salvianolic acid B on lipid peroxidation and metalloproteinase-2 activity in fibrotic liver in rat]
[Expression of matrix metalloproteinase 2 and 9 in liver tissue of patients with schistosomiasis japonica]
[Expression of matrix metalloproteinase-2 in rats with liver fibrosis]
[Mechanism of hepatic stellate cell migration during liver fibrosis]
[Serum markers of fibrosis and endothelial dysfunction in patients with alcoholism, with varying degrees of liver fibrosis].
[The effect of herbal compound 861 on mRNA levels of MMP-2 and its activities in experimental rats liver fibrosis]
[The role of changes of MMP-2, 9 activity in the development of liver fibrosis in rats]
Liver Cirrhosis, Alcoholic
Activity of MMP-2, MMP-8 and MMP-9 in serum as a marker of progression of alcoholic liver disease in people from Lublin Region, eastern Poland.
The decrease of serum MMP-2 activity corresponds to alcoholic cirrhosis stage.
Liver Diseases
Assessment of serum matrix metalloproteinases MMP-2 and MMP-9 after human liver transplantation: increased serum MMP-9 level in acute rejection.
Assessment of the clinical significance of serum matrix metalloproteinases MMP-2 and MMP-9 in patients with various chronic liver diseases and hepatocellular carcinoma.
Circulating gelatinases and tissue inhibitor of metalloproteinase-1 in colorectal cancer metastatic liver disease.
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Clinical Benefits of Biochemical Markers of Fibrosis in Egyptian Children With Chronic Liver Diseases.
Clinical implication of vascular cell adhesion molecule-1 and very late activation antigen-4 interaction, and matrix metalloproteinase-2 production in patients with liver disease.
Clinical significance of serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic liver disease.
Clinical usefulness of serum matrix metalloproteinase-2 concentration in patients with chronic viral liver disease.
Diagnostic potential of serum matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 as non-invasive markers of hepatic fibrosis in patients with HCV related chronic liver disease.
Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver.
Expression of matrix metalloproteinase-2 and -9 and their inhibitors in peripheral blood cells of patients with chronic hepatitis C.
Higher hepatic gene expression and serum levels of matrix metalloproteinase-2 are associated with steatohepatitis in non-alcoholic fatty liver diseases.
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study.
Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression.
Plasma Levels of Matrix Metalloproteinase (MMP)-2, MMP-9 and Tumor Necrosis Factor-? in Chronic Hepatitis C Virus Patients.
Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases -1 and -2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: comparison using ROC analysis.
Relationship between matrix metalloproteinase-2 activity and cystatin C levels in patients with hepatic disease.
Serum levels of tissue inhibitor of metalloproteinases-2 and of precursor form of matrix metalloproteinase-2 in patients with liver disease.
The proMMP-2 activation rate in patients with chronic viral liver disease.
[Clinical usefulness of plasma activities of gelatinase (matrix metalloproteinase-2 and 9) in chronic liver disease]
Liver Diseases, Alcoholic
Activity of MMP-2, MMP-8 and MMP-9 in serum as a marker of progression of alcoholic liver disease in people from Lublin Region, eastern Poland.
Formation and degradation of basement membrane collagen.
[Dynamic change and expression of matrix metalloproteinase-2, -9 in alcoholic liver disease in rats]
Liver Neoplasms
Atractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo.
Contribution of Nitric Oxide and Epidermal Growth Factor Receptor in Anti-Metastatic Potential of Paclitaxel in Human Liver Cancer Cell (HebG2).
Effect of all trans-retinoic acid on the secretion of IV collagenase.
Effects of siRNA-targeting BMP-2 on the abilities of migration and invasion of human liver cancer SMMC7721 cells and its mechanism.
Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo.
Inhibitory effect of bufalin combined with Hedgehog signaling pathway inhibitors on proliferation and invasion and metastasis of liver cancer cells.
Isolation of Fibroblast-Activation Protein-Specific Cancer-Associated Fibroblasts.
MiR-129-2 weakens proliferation and promotes apoptosis of liver cancer cells by suppressing the Wnt signaling pathway.
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Plumbagin inhibits invasion and migration of liver cancer HepG2 cells by decreasing productions of matrix metalloproteinase-2 and urokinase- plasminogen activator.
Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis.
Sonic Hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer.
The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun.
Ultra-small gold nanoparticles self-assembled by gadolinium ions for enhanced photothermal/photodynamic liver cancer therapy.
[Effect of Dahuang Zhechong Pills combined with TACE on VEGF, MMP-2, TGF-?1 and immune function of patients with primary liver cancer (blood stasis and collaterals blocking type)].
Lung Diseases
Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro.
Cigarette smoke exposure inhibits extracellular MMP-2 (gelatinase A) activity in human lung fibroblasts.
Elevated expression of MMP-2 and TIMP-2 cooperatively correlates with risk of lung cancer.
Evaluation of matrix metalloproteinase-2 in lung cancer.
Exploring the Role of Matrix Metalloproteinases as Biomarkers in Sporadic Lymphangioleiomyomatosis and Tuberous Sclerosis Complex. A Pilot Study.
Hyperoxia decreases matrix metalloproteinase-9 and increases tissue inhibitor of matrix metalloproteinase-1 protein in the newborn rat lung: association with arrested alveolarization.
Implications for matrix metalloproteinases as modulators of pediatric lung disease.
Increased matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase activity and expression in heterotopically transplanted murine tracheas.
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Matrix metalloproteinase-2, -7, and -9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases.
Matrix metalloproteinase-9 in lung remodeling.
Matrix metalloproteinases in lung diseases.
[The changes and effects of metalloproteinase-2 and tissue inhibitors of metalloproteinase-1 protein and mRNA expression in the lung tissue of neonatal rats with chronic lung disease induced by hyperoxia.]
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
Lung Diseases, Interstitial
Epimorphin expression in interstitial pneumonia.
Extracellular matrix metalloproteinase inducer in interstitial pneumonias.
Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases.
Lung Injury
Augmented metalloproteinase activity and acute lung injury in copper-deficient rats.
Collagenase and gelatinase activities in bronchoalveolar lavage fluids during bleomycin-induced lung injury.
Impact of Time on Fluid Resuscitation with Hypertonic Saline (NaCl 7.5%) in Rats with LPS-Induced Acute Lung Injury.
Increased 92 kD gelatinase activity from alveolar macrophages in newborn rats.
Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells.
Ionizing radiation enhances matrix metalloproteinase-2 production in human lung epithelial cells.
LPS-induced lung injury in neonatal rats: changes in gelatinase activities and consequences on lung growth.
Matrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia.
Matrix-Metallo-Proteinases and their tissue inhibitors in radiation-induced lung injury.
Metalloproteinase inhibition reduces lung injury and improves survival after cecal ligation and puncture in rats.
Neutrophil proteinases in hydrochloric acid- and endotoxin-induced acute lung injury: evaluation of interstitial protease activity by in situ zymography.
Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock.
Retinoic aacid diminished the expression of MMP-2 in hyperoxia-exposed premature rat lung fibroblasts through regulating mitogen-activated protein kinases.
Role of MMP2 and MMP9 in TRPV4-induced lung injury.
Role of stromelysin 1 and gelatinase B in experimental acute lung injury.
Selective PDE4 inhibitors as potent anti-inflammatory drugs for the treatment of airway diseases.
TGF-betal transgenic mouse model of thoracic irradiation: modulation of MMP-2 and MMP-9 in the lung tissue.
[Expression of various matrix metalloproteinases in mice with hyperoxia induced acute lung injury.]
[Retinoic acid diminished the expression of lung tissue matrix metalloproteinase-2 and matrix metalloproteinase-9 in hyperoxia-exposed premature rats through regulating mitogen-activated protein kinases]
Lung Neoplasms
3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NF?B Signaling Pathways.
72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells.
A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion.
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
A third-generation matrix metalloproteinase (MMP) inhibitor (ONO-4817) combined with docetaxel suppresses progression of lung micrometastasis of MMP-expressing tumor cells in nude mice.
Absence of CD9 enhances adhesion-dependent morphologic differentiation, survival, and matrix metalloproteinase-2 production in small cell lung cancer cells.
Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-kappaB and AP-1.
Activating transcription factor 1 promoted migration and invasion in lung cancer cells through regulating EGFR and MMP-2.
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Angelica sinensis suppresses human lung adenocarcinoma A549 cell metastasis by regulating MMPs/TIMPs and TGF-?1.
Anti-metastatic effect of cantharidin in A549 human lung cancer cells.
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line.
Aquaporin 1 promotes the proliferation and migration of lung cancer cell in vitro.
ARHGAP15 regulates lung cancer cell proliferation and metastasis via the STAT3 pathway.
Assessment of control tissue for gene and protein expression studies: a comparison of three alternative lung sources.
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Astragaloside IV increases MMP-2 mRNA and protein expression in human lung cancer A549 cells.
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways.
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer.
Bisphenol A stimulates human lung cancer cell migration via upregulation of matrix metalloproteinases by GPER/EGFR/ERK1/2 signal pathway.
BIX02189 inhibits TGF-?1-induced lung cancer cell metastasis by directly targeting TGF-? type I receptor.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Capn4 promotes non-small cell lung cancer progression via upregulation of matrix metalloproteinase 2.
Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9.
Chemoradiation in Lung Cancer: Effect on Levels of NGAL and Vitamin D in Serum.
Circulating tumor cells from a 4-dimensional lung cancer model are resistant to cisplatin.
CK2 inhibitor CX4945 induces sequential inactivation of proteins in the signaling pathways related with cell migration and suppresses metastasis of A549 human lung cancer cells.
Clinicopathologic significance of ?-catenin and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Combined therapeutic effect and molecular mechanisms of metformin and cisplatin in human lung cancer xenografts in nude mice.
Comparative expression of matrix metalloproteinases in internal malignancies and paired cutaneous metastatic lesions.
Correlation between a single nucleotide polymorphism in the matrix metalloproteinase-2 promoter and risk of lung cancer.
Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis.
Correlation of serum metalloproteinase levels with lung cancer metastasis and response to therapy.
Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway.
Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF).
Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma.
Degradation of tenascin-C and activity of matrix metalloproteinase-2 are associated with tumor recurrence in early stage non-small cell lung cancer.
Dehydrocostus Lactone Enhances Chemotherapeutic Potential of Doxorubicin in Lung Cancer by Inducing Cell Death and Limiting Metastasis.
Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK-Mediated Up-Regulation of MMP-2 and MMP-9.
Dietary flavonoid myricetin inhibits invasion and migration of radioresistant lung cancer cells (A549-IR) by suppressing MMP-2 and MMP-9 expressions through inhibition of the FAK-ERK signaling pathway.
Differences in Plasma MMPs and TIMPs Protein Expression and Chemotherapy Response in Patients with Tobacco- or Wood-Smoke-Induced Lung Cancer.
Effect of shRNA Mediated Down-Regulation of Annexin A2 on Biological Behavior of Human Lung Adencarcinoma Cells A549.
Efficient, enzyme responsive and tumor receptor targeting gelatin nanoparticles decorated with concanavalin-A for site-specific and controlled drug delivery for cancer therapy.
EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest.
Elastin-derived peptides increase invasive capacities of lung cancer cells by post-transcriptional regulation of MMP-2 and uPA.
Elevated activities of MMP-2 in the non-tumorous lung tissues of curatively resected stage I NSCLC patients are associated with tumor recurrence and a poor survival.
Elevated expression of MMP-2 and TIMP-2 cooperatively correlates with risk of lung cancer.
Elevated level of circulating matrix metalloproteinase-9 in patients with lung cancer.
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Evaluation of matrix metalloproteinase-2 in lung cancer.
Exosomal miR-106b serves as a novel marker for lung cancer and promotes cancer metastasis via targeting PTEN.
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Expression and the potential functions of TRIM32 in lung cancer tumorigenesis.
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Expression of metastasis-associated molecules in non-small cell lung cancer and their prognostic significance.
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Expression of type IV collagenase correlates with the expression of vascular endothelial growth factor in primary non-small cell lung cancer.
Fibulin-3 promoter methylation alters the invasive behavior of non-small cell lung cancer cell lines via MMP-7 and MMP-2 regulation.
FOXH1 promotes lung cancer progression by activating the Wnt/?-catenin signaling pathway.
Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.
Gaseous nitrogen oxide promotes human lung cancer cell line A549 migration, invasion, and metastasis via iNOS-mediated MMP-2 production.
Gelatin-degrading type IV collagenase isolated from human small cell lung cancer.
Gelatinolytic activity of matrix metalloproteinase in lung cancer studied using film in situ zymography stamp method.
Genetic polymorphisms in MMP 2, 9 and 3 genes modify lung cancer risk and survival.
Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.
GOLPH3 Overexpression is Closely Correlated with Poor Prognosis in Human Non-Small Cell Lung Cancer and Mediates its Metastasis Through Upregulating MMP-2 and MMP-9.
Granulocyte, granulocyte-macrophage, and macrophage colony-stimulating factors can stimulate the invasive capacity of human lung cancer cells.
Growth factor-enhanced expression and activity of matrix metalloproteases in human non-small cell lung cancer cell lines.
High Mobility Group Box Protein 1 Serves as a Potential Prognostic Marker of Lung Cancer and Promotes Its Invasion and Metastasis by Matrix Metalloproteinase-2 in a Nuclear Factor-?B-Dependent Manner.
Human papillomavirus up-regulates MMP-2 and MMP-9 expression and activity by inducing interleukin-8 in lung adenocarcinomas.
ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB.
IDH-Inhibiting Small Molecule DTDQ Inhibits Migration and Invasion of A549 Human Non-Small-Cell Lung Cancer Cells via Sequential Inactivation Of ERK and P38 Signaling Pathways.
IL-17A/IL-17RA promotes invasion and activates MMP-2 and MMP-9 expression via p38 MAPK signaling pathway in non-small cell lung cancer.
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer.
Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells.
Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Integrin ?v?6 Promotes Lung Cancer Proliferation and Metastasis through Upregulation of IL-8-Mediated MAPK/ERK Signaling.
Intracellular expression of a single-chain antibody directed against type IV collagenase inhibits the growth of lung cancer xenografts in nude mice.
Is a single nucleotide polymorphism a risk factor for lung cancer in the matrix metalloproteinase-2 promoter?
Kaempferol Suppresses Transforming Growth Factor-?1-Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-179.
MAG-2 promotes invasion, mobility and adherence capability of lung cancer cells by MMP-2, CD44 and intracellular calcium in vitro.
Matrix metalloproteinase 2 polymorphisms and expression in lung cancer: a meta-analysis.
Matrix metalloproteinase activity in early-stage lung cancer.
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.
MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-2.
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells.
MMP-2 and MMP-13 affect vasculogenic mimicry formation in large cell lung cancer.
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9.
N-myc downstream regulated gene 2 overexpression reduces matrix metalloproteinase-2 and -9 activities and cell invasion of A549 lung cancer cell line in vitro.
Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms.
Naringenin inhibits migration of lung cancer cells via the inhibition of matrix metalloproteinases-2 and -9.
Non-steroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 expression via repression of transcription in lung cancer cells.
Nonsteroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 via suppression of the ERK/Sp1-mediated transcription.
Osthole suppresses migration and invasion of A549 human lung cancer cells through inhibition of matrix metalloproteinase-2 and matrix metallopeptidase-9 in vitro.
Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.
Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer.
Overexpression of matrix metalloproteinase-7 and -9 in NSCLC tumor and stromal cells: Correlation with a favorable clinical outcome.
Pipoxolan inhibits CL1-5 lung cancer cells migration and invasion through inhibition of MMP-9 and MMP-2.
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells.
Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects.
Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients.
Prognostic impact of MMP-2 and MMP-9 expression in pathologic stage IA non-small cell lung cancer.
Prognostic significance of overexpressed matrix metalloproteinase-2, mouse-double minute: 2 homolog and epidermal growth factor receptor in non-small cell lung cancer.
Prognostic value of tissue inhibitor of metalloproteinase-2 expression in patients with non-small cell lung cancer: a systematic review and meta-analysis.
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Quantitative Assessment of the Effects of MMP-2 Polymorphisms on Lung Carcinoma Risk.
Quercetin metabolites inhibit MMP-2 expression in A549 lung cancer cells by PPAR-? associated mechanisms.
Rap2b promotes proliferation, migration, and invasion of lung cancer cells.
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Relationship between matrix metalloproteinase 2 and lung cancer progression.
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases.
Rho Guanine Nucleotide Exchange Factor 5 Increases Lung Cancer Cell Tumorigenesis via MMP-2 and Cyclin D1 Upregulation.
Salinomycin suppresses TGF-?1-induced EMT by down-regulating MMP-2 and MMP-9 via the AMPK/SIRT1 pathway in non-small cell lung cancer.
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells.
Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma.
Steroidal Saponins from Paris polyphylla Suppress Adhesion, Migration and Invasion of Human Lung Cancer A549 Cells Via Down-Regulating MMP-2 and MMP-9.
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung adenocarcinoma epithelial cells.
Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies.
Targeting of gelatinase activity with a radiolabeled cyclic HWGF peptide.
The association of MMP-9 enzyme activity, MMP-9 C1562T polymorphism, and MMP-2 and -9 and TIMP-1, -2, -3, and -4 gene expression in lung cancer.
The Butanol Fraction of Guava (Psidium cattleianum Sabine) Leaf Extract Suppresses MMP-2 and MMP-9 Expression and Activity Through the Suppression of the ERK1/2 MAPK Signaling Pathway.
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
The relationship of metalloproteinase gene polymorphisms and lung cancer.
The Role of Matrix Metalloproteinase 2 on the Survival of Patients with Non-Small Cell Lung Cancer: A Systematic Review with Meta-Analysis.
The VEGFR2, COX-2 and MMP-2 polymorphisms are associated with clinical outcome of patients with inoperable non-small cell lung cancer.
Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway.
Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and ?-catenin signaling pathways.
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Tumor suppressive roles of eugenol in human lung cancer cells.
Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression.
Type IV collagenase/gelatinase (MMP-2) is not increased in plasma of patients with cancer.
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
[Effect of cyclooxygenase-2,and matrix metalloproteinase-2 expression on prognosis of lung cancer]
[Effect of hypoxia on infiltration and migration of lung cancer cells and expression of MMP-2 and TIMP-2.]
[Effect of Src tyrosine kinase inhibition on secretion of MMP-2 and MMP-9 by non-small cell lung cancer cells].
[Expression and pathological mechanism of MMP-9 and HIF-2? in CD133(+) lung cancer stem cells].
[Expression and significance of matrix metalloproteinases and their tissue inhibitors in the infiltration and metastasis of lung cancer.]
[Expression of bone morphogenetic proteins, matrix metalloproteinases and inhibitors of matrix metalloproteinases in lung cancers and their prognostic significance]
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
[Preliminary study of dihydroartemisin in inhibiting invasion and metastasis of hepatoma cells].
[Prognostic impact of matrix metalloproteinases 2,9, and 11 in stromal cells stage I non-small cell lung cancer]
[Promotion of MAG-1 on Metastasis of Lung Cancer Cells in vitro and Its Expression in Lung Cancer Tissue of 24 Cases.]
[Significance of caveolin-1 protein detected by quantum dots technique in human lung cancer invasiveness and metastasis.]
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
[The role of CXCR4 in lung cancer metastasis and its possible mechanism]
Lupus Erythematosus, Cutaneous
Matrix metalloproteinase-2 and -9 activity levels increase in cutaneous lupus erythematosus lesions and correlate with disease severity.
Lupus Erythematosus, Systemic
Elevated circulatory MMP-2 and MMP-9 levels and activities in patients with rheumatoid arthritis and systemic lupus erythematosus.
Elevated serum levels of MMP-2, MMP-3, and MMP-13 in Chinese patients with systemic lupus erythematosus.
Expression of the matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 in systemic lupus erythematosus patients.
Matrix metalloproteinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMP-2 level and increased risk of cardiovascular disease in systemic lupus erythematosus patients.
Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2.
Role of MMP-2 and its inhibitor TIMP-2 as biomarkers for susceptibility to systemic lupus erythematosus.
Lupus Nephritis
Glomerular expression of matrix metalloproteinases in systemic lupus erythematosus in association with activity index and renal function.
Prediction Of Renal Flare In Adult Patients With Lupus Induced Nephritis.
Relationship of cell-free urine MicroRNA with lupus nephritis in children.
Relationships between MMP-2, MMP-9, TIMP-1 and TIMP-2 levels and their pathogenesis in patients with lupus nephritis.
Significance of MMP-2 and TIMP-2 mRNA expressions on glomerular cells in the development of glomerulosclerosis.
Lyme Disease
Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis.
Host metalloproteinases in Lyme arthritis.
Lymphadenopathy
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Lymphangioleiomyomatosis
Doxycycline inhibits matrix metalloproteinase-2 secretion from TSC2-null mouse embryonic fibroblasts and lymphangioleiomyomatosis cells.
Doxycycline use in patients with lymphangioleiomyomatosis: safety and efficacy in metalloproteinase blockade.
Immunohistochemical study of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in pulmonary lymphangioleiomyomatosis (LAM).
Lymphatic Metastasis
Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Association of single nucleotide polymorphisms of ?2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma.
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinoma.
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients.
Endometrial tumor invasiveness is related to metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expressions.
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression.
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Expression of MMP-2 and TIMP-3 with incidence and prognosis of giant-cell tumor of the bone.
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology.
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases.
Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography.
Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1{alpha}, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma.
HAND2-AS1 inhibits invasion and metastasis of cervical cancer cells via microRNA-330-5p-mediated LDOC1.
High expression of osteoglycin decreases gelatinase activity of murine hepatocarcinoma Hca-F cells.
High MMP-21 expression in metastatic lymph nodes predicts unfavorable overall survival for oral squamous cell carcinoma patients with lymphatic metastasis.
HMGA2 gene silencing reduces epithelial-mesenchymal transition and lymph node metastasis in cervical cancer through inhibiting the ATR/Chk1 signaling pathway.
Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours.
Immunohistochemical distribution of type IV collagenase in normal, dysplastic and neoplastic canine mammary gland.
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Immunohistochemical levels of matrix metalloproteinase-2 and CD44 variant 6 protein in the diagnosis and lateral cervical lymph node metastasis of papillary thyroid carcinoma.
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Intratumoral macrophage counts correlate with tumor progression in colorectal cancer.
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
LABAZ1: A metastatic tumor model for renal cell carcinoma expressing the carbonic anhydrase type 9 tumor antigen.
Low expression of RECK in oral squamous cell carcinoma patients induces a shorter survival rate through an imbalance of RECK/MMPs.
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Pancreatic Stellate Cells Activation and Matrix Metallopeptidase 2 Expression Correlate With Lymph Node Metastasis in Pancreatic Carcinoma.
Papers to appear in forthcoming issues
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables.
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection.
Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in human cutaneous melanoma.
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Serum MMP-2 as a potential predictive marker for papillary thyroid carcinoma.
Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell.
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma.
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma.
Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas.
VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein.
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
[Expression of matrix metalloproteinase-2 in hypopharyngeal carcinoma and its clinical significance]
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
[Expression of matrix metalloproteinase-2,9 in hypopharyngeal carcinoma and its relationship with lymphatic metastasis]
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
[Expression of MMP-2, MMP-9, TIMP-1 and their relationship with prognosis in NSCLC.]
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
[Expressions of COX-2 and MMP-2 in nasopharyngeal carcinoma and the their relationship with lymph node metastasis]
[Expressions of vascular endothelial growth factor C and matrix metalloproteinases-2 and prognosis of non-small cell lung carcinoma.]
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
[Relationship between expression of MMP-2 and prognosis in human laryngeal squamous cell carcinoma].
[Role of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factor C in lymph node metastasis of breast cancer.]
[Study of type I and IV collagenase activity in human thyroid diseases]
[Study on expression of matrix metalloproteinases and their inhibitors in parotid gland tumors]
[The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas]
[The effects of MMPs and TIMPs on the metastasis of oral squamous cell carcinoma to neck lymph nodes]
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
[The expression of MMP-2, E-cadherin in supraglottic carcinoma and their relationship with cervical lymph nody metastasis]
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
Lymphocele
Doxycycline sclerotherapy of lymphocele after renal transplantation and its inhibition of gelatinase activity.
Lymphoma
CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway.
Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases.
Emmprin, a cell surface inducer of matrix metalloproteinases (MMPs), is expressed in T-cell lymphomas.
Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas.
Gelatinases (MMP-2 and MMP-9), TIMP-1 expression and the extent of neovascularization in aggressive non-Hodgkin's lymphomas.
Interleukin-6 regulation of matrix metalloproteinase (MMP-2 and MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) expression in malignant non-Hodgkin's lymphomas.
Lack of prognostic value of MMP-9 expression and immunohistochemically defined germinal center phenotype in patients with diffuse large B-cell lymphoma treated with modern chemotherapy with or without CD20 antibody.
Matrix metalloproteinase-9 and vascular endothelial growth factor: a possible link in adult T-cell leukaemia cell invasion.
Matrix-metalloproteinases in Hodgkin lymphoma.
Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.
The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma.
The Expression of Matrix Metalloproteinases in Eyes with Intraocular Lymphoma.
VEGF and MMP-9: biomarkers for canine lymphoma.
Lymphoma, B-Cell
Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax signaling pathways.
CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway.
circRPS28 (hsa_circ_0049055) is a novel contributor for papillary thyroid carcinoma by regulating cell growth and motility via functioning as ceRNA for miR-345-5p to regulate frizzled family receptor 8 (FZD8).
Combination Efficacy of Astragalus membranaceus and Curcuma wenyujin at Different Stages of Tumor Progression in an Imageable Orthotopic Nude Mouse Model of Metastatic Human Ovarian Cancer Expressing Red Fluorescent Protein.
Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways.
Knockdown of REG? inhibits the proliferation and migration and promotes the apoptosis of multiple myeloma cells by downregulating NF-?B signal pathway.
microRNA-613 exerts anti-angiogenic effect on nasopharyngeal carcinoma cells through inactivating the AKT signaling pathway by down-regulating FN1.
Protective effect of genistein isolated from Hydrocotyle sibthorpioides on hepatic injury and fibrosis induced by chronic alcohol in rats.
Sanguinarine inhibits growth and invasion of gastric cancer cells via regulation of the DUSP4/ERK pathway.
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Lymphoma, Follicular
Prognostic significance of p53 and matrix metalloproteinase-9 expression in follicular lymphoma.
Lymphoma, Non-Hodgkin
Association between matrix metalloproteinase 2 (MMP2) promoter polymorphisms and the susceptibility to non-Hodgkin's lymphoma in Egyptians.
Human neutrophil gelatinase: a marker for circulating blood neutrophils. Purification and quantitation by enzyme linked immunosorbent assay.
Large B-cell lymphoma of the leg--complete remission with perilesional interferon alpha.
Matrix metalloproteinase-2 promoter and tissue inhibitor of metalloproteinase-2 gene polymorphisms in non-Hodgkin's lymphoma.
Matrix Metalloproteinase-2 Single Nucleotide Polymorphism in Egyptian Non-Hodgkin Lymphoma Patients: Correlation with Clinicopathological Characteristics and Outcome.
Plasma MMP-2-TIMP-2 complex levels measured during follow-up predict a risk of relapse in patients with malignant lymphoma.
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in Hodgkin's and non-Hodgkin's lymphoma.
Role of gelatinases (MMP-2 and MMP-9), TIMP-1, vascular endothelial growth factor (VEGF), and microvessel density on the clinicopathological behavior of childhood non-Hodgkin lymphoma.
Lymphoma, T-Cell
miRNA-218 inhibits osteosarcoma cell migration and invasion by down-regulating of TIAM1, MMP2 and MMP9.
Lymphoma, T-Cell, Cutaneous
Matrix metalloproteinase-2 promoter genotype as a marker of cutaneous T-cell lymphoma early stage.
Lymphopenia
Recombinant mouse granulocyte chemotactic protein-2: production in bacteria, characterization, and systemic effects on leukocytes.
Macular Degeneration
Age-dependent variation in metalloproteinase activity of isolated human Bruch's membrane and choroid.
Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium implications for age-related macular degeneration.
Association analysis of genetic polymorphisms and expression levels of selected genes involved in extracellular matrix turnover and angiogenesis with the risk of age-related macular degeneration.
Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women.
Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration.
Matrix metalloproteinase (MMP) expression in experimental choroidal neovascularization.
Meta-analysis of the rs243865 MMP-2 polymorphism and age-related macular degeneration risk.
MMP-2 and MMP-9 synergize in promoting choroidal neovascularization.
MMP-2 Rs24386 (C-->T) gene polymorphism and the phenotype of age-related macular degeneration.
Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
Plasma levels of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9) in age-related macular degeneration.
Reduced choroidal neovascular membrane formation in matrix metalloproteinase-2-deficient mice.
Risk of macular degeneration affected by polymorphisms in Matrix metalloproteinase-2: A case-control study in Chinese Han population.
Role of MMP-2 (-1306?C/T) Polymorphism in Age-Related Macular Degeneration.
Serum levels of matrix metalloproteinase 2 and matrix metalloproteinase 9 elevated in polypoidal choroidal vasculopathy but not in age-related macular degeneration.
The Role of Matrix Metalloproteinases Polymorphisms in Age-Related Macular Degeneration.
The Role of MMP2 (-1306C>T) and TIMP2 (-418 G>C) Promoter Variants in Age-related Macular Degeneration.
[Prevention and treatment of age-related macular degeneration by extract of Fructus lycii and its constituents lutein/zeaxanthin: an in vive and in vitro experimental research].
Macular Edema
The relationship between plasma MMP-9 and TIMP-2 levels and intraocular pressure elevation in diabetic patients after intravitreal triamcinolone injection.
Malnutrition
Long-term effects of maternal undernutrition on offspring carotid artery remodeling: role of miR-29c.
Mania
Expression of matrix metalloproteinases in patients with bipolar disorder.
Marfan Syndrome
Immunohistochemistry of matrix metalloproteinases and their inhibitors in thoracic aortic aneurysms and aortic valves of patients with Marfan's syndrome.
Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.
Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.
MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.
Mastitis
Increase in milk metalloproteinase activity and vascular permeability in bovine endotoxin-induced and naturally occurring Escherichia coli mastitis.
Mastocytoma
Dog mast cell alpha-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain.
Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase.
Medulloblastoma
Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors.
Matrix metalloproteinase expression in childhood medulloblastomas/primitive neuroectodermal tumors.
MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors.
Significant differences in the matrix metalloproteinase expression profiles of spontaneous medulloblastomas/primitive neuroectodermal tumors as compared with their xenografted, established tumor cell line derived counterparts.
Melanoma
(-)-Oleocanthal exerts anti-melanoma activities and inhibits STAT3 signaling pathway.
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces matrix metalloproteinase (MMP) expression and invasion in A2058 melanoma cells.
?-Elemene inhibits the metastasis of B16F10 melanoma cells by downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9.
A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells.
A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of alpha1beta1, alpha4beta1 and alpha6beta1 integrins.
A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.
A novel matrix metalloproteinase-2 inhibitor triazolylmethyl aziridine reduces melanoma cell invasion, angiogenesis and targets ERK1/2 phosphorylation.
A novel synthetic oleanane triterpenoid suppresses adhesion, migration, and invasion of highly metastatic melanoma cells by modulating gelatinase signaling axis.
A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells.
A prognostic index in skin melanoma through the combination of matrix metalloproteinase-2, Ki67, and p53.
A specific sequence of the noncollagenous domain of the alpha3(IV) chain of type IV collagen inhibits expression and activation of matrix metalloproteinases by tumor cells.
Acetylsalicylic acid regulates MMP-2 activity and inhibits colorectal invasion of murine B16F0 melanoma cells in C57BL/6J mice: Effects of prostaglandin F(2)alpha.
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis.
Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity.
Activation of Stat3 in Human Melanoma Promotes Brain Metastasis.
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen.
Alpha-V-dependent outside-in signaling is required for the regulation of CD44 surface expression, MMP-2 secretion, and cell migration by osteopontin in human melanoma cells.
Alterations in endothelial cell proteinase and inhibitor polarized secretion following treatment with interleukin-1, phorbol ester, and human melanoma cell conditioned medium.
An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells.
Angiopoietin-like 4 promotes melanoma cell invasion and survival through aldolase A.
Anti-angiogenesis effect of essential oil from Curcuma zedoaria in vitro and in vivo.
Anti-metastatic Effects of Cationic KT2 Peptide (a Lysine/Tryptophan-rich Peptide) on Human Melanoma A375.S2 Cells.
Anti-tumor activities of chondroitinase AC and chondroitinase B: inhibition of angiogenesis, proliferation and invasion.
Anticancer Efficacy of Polyphenols and Their Combinations.
Antimetastatic potential of vernolide-A, a sesquiterpenoid from Vernonia cinerea L.
Antiproliferative and anti-invasive effects of inorganic and organic arsenic compounds on human and murine melanoma cells in vitro.
Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma.
Apoptosis induction by 4-nerolidylcatechol in melanoma cell lines.
AT1 receptors activation enhances the expression of MMP-2, MMP-13 and VEGF but not MMP-9 in B16F10 melanoma cells.
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.
Basal caspase-3 activity promotes migration, invasion, and vasculogenic mimicry formation of melanoma cells.
Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts.
Beneficial regulation of matrixmetalloproteinases and their inhibitors, fibrillar collagens and transforming growth factor-beta by Polypodium leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells.
Binding of alpha5 monoclonal antibody to cell surface alpha5beta1 integrin modulates MMP-2 and MMP-7 activity in B16F10 melanoma cells.
Black tea polyphenol (theaflavin) downregulates MMP-2 in human melanoma cell line A375 by involving multiple regulatory molecules.
BM-40 and MMP-2 expression are not coregulated in human melanoma cell lines.
Bornyl cis-4-Hydroxycinnamate Suppresses Cell Metastasis of Melanoma through FAK/PI3K/Akt/mTOR and MAPK Signaling Pathways and Inhibition of the Epithelial-to-Mesenchymal Transition.
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Cantharidin Impairs Cell Migration and Invasion of A375.S2 Human Melanoma Cells by Suppressing MMP-2 and -9 Through PI3K/NF-?B Signaling Pathways.
Casticin Inhibits A375.S2 Human Melanoma Cell Migration/Invasion through Downregulating NF-?B and Matrix Metalloproteinase-2 and -1.
CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas.
CD44-epidermal growth factor receptor interaction mediates hyaluronic acid-promoted cell motility by activating protein kinase C signaling involving Akt, Rac1, Phox, reactive oxygen species, focal adhesion kinase, and MMP-2.
Cell membrane-associated MT1-MMP-dependent activation of pro-MMP-2 in A375 melanoma cells.
Cell surface chondroitin sulfate glycosaminoglycan in melanoma: role in the activation of pro-MMP-2 (pro-gelatinase A).
Cellular adhesion pathways and metastatic potential of human melanoma.
Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis.
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
Co-regulated expression of matrix metalloproteinase-2 and transforming growth factor-beta in melanoma development and progression.
Coexpression of integrin alpha(v)beta3 and matrix metalloproteinase-2 (MMP-2) coincides with MMP-2 activation: correlation with melanoma progression.
Comparison of the prognostic value of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Control of melanoma invasiveness by anticollagenolytic agents: a reappraisal of an old concept.
Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma.
CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells.
Culture of human A375 melanoma cells in the presence of fibronectin causes expression of MMP-9 and activation of MMP-2 in culture supernatants.
Cumulative influence of matrix metalloproteinase-1 and -2 in the migration of melanoma cells within three-dimensional type I collagen lattices.
Cytochalasin D disruption of actin filaments in 3T3 cells produces an anti-apoptotic response by activating gelatinase A extracellularly and initiating intracellular survival signals.
Cytochrome P450 17 (CYP17) Is Involved in Endometrial Cancinogenesis Through Apoptosis and Invasion Pathways.
Cytokine sensitivity of metastatic human melanoma cell lines-- simultaneous inhibition of proliferation and enhancement of gelatinase activity.
Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.
Danshensu has anti-tumor activity in B16F10 melanoma by inhibiting angiogenesis and tumor cell invasion.
De-N-acetyl GM3 promotes melanoma cell migration and invasion through urokinase plasminogen activator receptor signaling-dependent MMP-2 activation.
Decreased expression levels of cell cycle regulators and matrix metalloproteinases in melanoma from RET-transgenic mice by single irradiation of non-equilibrium atmospheric pressure plasmas.
Different levels of TGFbeta, IL-10, IFNgamma and gelatinase A occur in experimental white and black metastases induced by bryostatin 1 or by phorbol ester-treated BL6T murine melanoma cells.
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Diverse matrix metalloproteinase functions regulate cancer amoeboid migration.
Diversity of melanoma plasma membrane proteinases: inhibition of collagenolytic and cytolytic activities by minocycline.
Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo.
Down-regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP-2 and inducing mesenchymal-to-epithelial transition.
Downregulation of BRCA1 in A375 melanoma cell line increases radio-sensitivity and modifies metastatic and angiogenic gene expression.
Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model.
Doxycycline influences microcirculation patterns in b16 melanoma.
Effect of curcumin on gelatinase A (MMP-2) activity in B16F10 melanoma cells.
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line.
Eicosapentaenoic acid reduces the invasive and metastatic activities of malignant tumor cells.
eIF4E Is an Adverse Prognostic Marker of Melanoma Patient Survival by Increasing Melanoma Cell Invasion.
Elastin-derived peptides upregulate matrix metalloproteinase-2-mediated melanoma cell invasion through elastin-binding protein.
Elastin-elastases and inflamm-aging.
Electrophoretic analysis of proteins associated with tumor cell invasion.
Emerging Roles of PAR-1 and PAFR in Melanoma Metastasis.
Epigallocatechingallate inhibits migration of human uveal melanoma cells via downregulation of matrix metalloproteinase-2 activity and ERK1/2 pathway.
Evaluation of EMMPRIN and MMP-2 in the prognosis of primary cutaneous malignant melanoma.
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Expression and activation of pro-gelatinase A by human melanoma cell lines with different tumorigenic potential.
Expression and distribution of MMPs and TIMPs in human uveal melanoma.
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Expression and serum levels of MMP-2 and MMP-9 during human melanoma progression.
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
Expression of Id-1 is regulated by MCAM/MUC18: A missing link in melanoma progression.
Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo.
Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.
Expression of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of MMP (TIMP)-1 in conjunctival melanomas and clinical implications.
Expression of matrix metalloproteinase-2 and -9 and membrane-type 1 matrix metalloproteinase in melanocytic tumors of dogs and canine melanoma cell lines.
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization.
Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells.
Fra-2/AP-1 regulates melanoma cell metastasis by downregulating Fam212b.
Fully human antibodies to MCAM/MUC18 inhibit tumor growth and metastasis of human melanoma.
Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma.
Gallic acid inhibits the migration and invasion of A375.S2 human melanoma cells through the inhibition of matrix metalloproteinase-2 and Ras.
Gelatinase A activity directly modulates melanoma cell adhesion and spreading.
Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells.
Gold(I) Biscarbene Complexes Derived from Vascular-Disrupting Combretastatin A-4 Address Different Targets and Show Antimetastatic Potential.
Gonadotropin-releasing hormone agonists suppress melanoma cell motility and invasiveness through the inhibition of alpha3 integrin and MMP-2 expression and activity.
Halogenated bis(methoxy-benzylidene)-4-piperidone curcuminoids with improved anticancer activity.
HDAC-inhibitor (S)-8 disrupts HDAC6-PP1 complex prompting A375 melanoma cell growth arrest and apoptosis.
Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin ?v?5-induced secretion of VEGF-A.
Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.
Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.
Human melanoma cell invasion is inhibited in vitro by swainsonine and deoxymannojirimycin with a concomitant decrease in collagenase IV expression.
Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin ?(v)?(3) interaction.
Hypoxia influences vasculogenic mimicry channel formation and tumor invasion-related protein expression in melanoma.
Hypoxia-induced senescence contributes to the regulation of microenvironment in melanomas.
Identification of activated matrix metalloproteinase-2 (MMP-2) as the main gelatinolytic enzyme in malignant melanoma by in situ zymography.
Identification of AP-2-regulated genes by macroarray profiling of gene expression in human A375P melanoma.
Identification of arachidonic acid pathways required for the invasive and metastatic activity of malignant tumor cells.
Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease.
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Immunolocalisation studies of matrix metalloproteinases-1, -2 and -3 in human melanoma.
In Vitro Methods to Study the Modulation of Migration and Invasion by Sphingosine-1-Phosphate.
In vivo and in vitro antitumor effect of ascorbic acid, lysine, proline and green tea extract on human melanoma cell line A2058.
In vivo antitumoral effect of 4-nerolidylcatechol (4-NC) in NRAS-mutant human melanoma.
Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma.
Independent expression and cellular processing of Mr 72,000 type IV collagenase and interstitial collagenase in human tumorigenic cell lines.
Induction of secreted matrix metalloproteinase-9 activity in human melanoma cells by extracellular matrix proteins and cytokines.
Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor.
Influence of cultured dermal fibroblasts on human melanoma cell proliferation, matrix metalloproteinase-2 (MMP-2) expression and invasion in vitro.
Inhibition of PKCalpha decreases the gelatinase activity and the angiogenic and metastatic ability of the highly metastatic B16 murine melanoma cells.
Inhibition of the Epigenetic Reader BRD4 Reduces SIRP?-Mediated Phagocytosis and Melanoma Invasion.
Inhibition of the STAT3 Signaling Pathway Contributes to the Anti-Melanoma Activities of Shikonin.
Inhibition of tumor growth by ?-elemene through downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9 in a murine intraocular melanoma model.
Inhibitory effect of norcantharidin on melanoma tumor growth and vasculogenic mimicry by suppressing MMP-2 expression.
Intact vitronectin induces matrix metalloproteinase-2 and tissue inhibitor of metalloproteinases-2 expression and enhanced cellular invasion by melanoma cells.
Integrin alpha5beta1 controls invasion of human breast carcinoma cells by direct and indirect modulation of MMP-2 collagenase activity.
Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases.
Invasion-associated MMP-2 and MMP-9 are up-regulated intracellularly in concert with apoptosis linked to melanoma cell detachment.
Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells.
Involvement of tumor cell integrin alpha v beta 3 in hematogenous metastasis of human melanoma cells.
Laminin increases the release of type IV collagenase from malignant cells.
Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells.
Liver metastasis formation by laminin-1 peptide (LQVQLSIR)-adhesion selected B16-F10 melanoma cells.
LKB1 loss cooperating with BRAF V600E promotes melanoma cell invasion and migration by up-regulation MMP-2 via PI3K/Akt/mTOR pathway.
LncRNA GAS5 is a critical regulator of metastasis phenotype of melanoma cells and inhibits tumor growth in vivo.
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.
Locally generated VGVAPG and VAPG elastin-derived peptides amplify melanoma invasion via the galectin-3 receptor.
Long noncoding RNA HOTAIR is associated with motility, invasion, and metastatic potential of metastatic melanoma.
Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
Loss of cell invasiveness through PKC-mediated syndecan-1 downregulation in melanoma cells under anchorage independency.
Loss of dipeptidyl peptidase IV immunostaining discriminates malignant melanomas from deep penetrating nevi.
Luteolin inhibits proliferation and induces apoptosis of human melanoma cells in vivo and in vitro by suppressing MMP-2 and MMP-9 through the PI3K/AKT pathway.
Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis.
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value.
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma?
Matrix Metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory T(H)2 Cells via an IL-12- and OX40L-Dependent Pathway.
Matrix metalloproteinase-2 is expressed in melanoma-associated spongiform scleropathy.
Matrix metalloproteinase-2 Promotes ?v?3 Integrin-Mediated Adhesion and Migration of Human Melanoma Cells by Cleaving Fibronectin.
Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression.
Matrix metalloproteinases in human melanoma.
Matrix metalloproteinases MMP-1, MMP-2, and MMP-13 are overexpressed in primary nodular melanoma.
MDA-9/Syntenin Is Essential for Factor VIIa-induced Signaling, Migration, and Metastasis in Melanoma Cells.
Mediation of NGF-stimulated extracellular matrix invasion by the human melanoma low-affinity p75 neurotrophin receptor: melanoma p75 functions independently of trkA.
Melanocytes in nevi and melanomas synthesize basement membrane and basement membrane-like material. An immunohistochemical and electron microscopic study including immunoelectron microscopy.
Melanoma Biomolecules: Independently Identified but Functionally Intertwined.
Melanoma Cell Resistance to Vemurafenib Modifies Inter-Cellular Communication Signals.
Melanoma differentiation-associated gene-7/interleukin 24 inhibits invasion and migration of human cervical cancer cells in vitro.
Melanoma invasion in reconstructed human skin is influenced by skin cells--investigation of the role of proteolytic enzymes.
Microtubule-dependent matrix metalloproteinase-2/matrix metalloproteinase-9 exocytosis: prerequisite in human melanoma cell invasion.
MMP-2 and TIMP-2 in Cutaneous Melanoma: Association With Prognostic Factors and Description in Cutaneous Metastases.
MMP-2 expression in uveal melanoma: differential activation status dictated by the cellular environment.
MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light.
MMP-9 is predominantly expressed in epithelioid and not spindle cell uveal melanoma.
MMP2 and TLRs modulate immune responses in the tumor microenvironment.
Modulation of innate immunity in the tumor microenvironment.
Modulation of MMP-2 and -9 secretion by cytokines, inducers and inhibitors in human melanoma A-2058 cells.
Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis.
Molecular cloning of seprase: a serine integral membrane protease from human melanoma.
Molecular role(s) for integrins in human melanoma invasion.
Monocyte membrane type 1-matrix metalloproteinase. Prostaglandin-dependent regulation and role in metalloproteinase-2 activation.
NADPH oxidase 1 overexpression enhances invasion via matrix metalloproteinase-2 and epithelial-mesenchymal transition in melanoma cells.
Neural cell adhesion molecule potentiates invasion and metastasis of melanoma cells through CAMP-dependent protein kinase and phosphatidylinositol 3-kinase pathways.
Neuropilin-1 expression promotes invasiveness of melanoma cells through vascular endothelial growth factor receptor-2-dependent and -independent mechanisms.
Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma.
Nonlethal Levels of Zeaxanthin Inhibit Cell Migration, Invasion, and Secretion of MMP-2 via NF-?B Pathway in Cultured Human Uveal Melanoma Cells.
Novel biomarkers in malignant melanoma.
NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo.
Nucleosome assembly protein 1-like 4, a new therapeutic target for proliferation and invasion of melanoma cells.
Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha /IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways.
Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells.
Osteopontin: it's role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression.
Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro.
Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS.
Oxytocin involves in chronic stress-evoked melanoma metastasis via ?-arrestin 2-mediated ERK signaling pathway.
Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma.
Papers to appear in forthcoming issues
Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.
PKC and PKA phosphorylation affect the subcellular localization of claudin-1 in melanoma cells.
Plasmacytoid dendritic cells support melanoma progression by promoting Th2 and regulatory immunity through OX40L and ICOSL.
Platelet-activating factor mediates MMP-2 expression and activation via phosphorylation of cAMP-response element-binding protein and contributes to melanoma metastasis.
Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by suppressing MMP?2 and MMP?9 via downregulation of NF-?B signaling pathway.
Potential MMP2-mediated availability of HLA binding, mutant ECM peptides reflects better melanoma survival rates and greater T-cell infiltrates.
Predicting Novel Antitumor Agents: 3D-Pharmacophore Mapping of ?-N-biaryl Ether Sulfonamide-Based Hydroxamates as Potentially MMP-2 Inhibitors.
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Prognostic significance of KAI1/CD82 in human melanoma and its role in cell migration and invasion through the regulation of ING4.
Prognostic significance of the expression of nuclear eukaryotic translation initiation factor 5A2 in human melanoma.
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma.
PSY-1, a Taxus chinensis var. mairei extract, inhibits cancer cell metastasis by interfering with MMPs.
Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2alpha and protease-activated receptor-1 expression during melanoma progression.
Reciprocal effects of ascorbate on cancer cell growth and the expression of matrix metalloproteinases and transforming growth factor-beta.
Recombinant interferon alpha and gamma modulate the invasive potential of human melanoma in vitro.
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.
Regulation of gene expression in melanoma: new approaches for treatment.
Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway.
Retinoid-mediated suppression of tumor invasion and matrix metalloproteinase synthesis.
RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2.
Role and regulation of the thrombin receptor (PAR-1) in human melanoma.
Role of ?-catenin signaling in the anti-invasive effect of the omega-3 fatty acid DHA in human melanoma cells.
Role of AP-2 in tumor growth and metastasis of human melanoma.
Selection of invasive and metastatic subpopulations from a heterogeneous human melanoma cell line.
Serum markers in early-stage and locally advanced melanoma.
Serum matrix metalloproteinase-2 as a prognostic marker in advanced cutaneous melanoma.
Serum matrix metalloproteinase-2 in patients with malignant melanoma.
Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells.
Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo.
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
Suppression of basement membrane type IV collagen degradation and cell invasion in human melanoma cells expressing an antisense RNA for MMP-1.
Synthesis and antimetastatic activity evaluation of cinnamic acid derivatives containing 1,2,3-triazolic portions.
Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells.
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.
Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice.
Targeting the tumor microenvironment with chemically modified tetracyclines: inhibition of laminin 5 gamma2 chain promigratory fragments and vasculogenic mimicry.
Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells.
The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion.
The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts.
The effect of ultraviolet radiation on choroidal melanocytes and melanoma cell lines: cell survival and matrix metalloproteinase production.
The expression of MMP-2 and Ki-67 in head and neck melanoma, and their correlation with clinic-pathologic indices.
The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance.
The influence of different microenvironments on melanoma invasiveness and microcirculation patterns: an animal experiment study in the mouse model.
The Interplay of MicroRNA-34a, LGR4, EMT-Associated Factors, and MMP2 in Regulating Uveal Melanoma Cells.
The involvement of Notch signaling in melanoma vasculogenic mimicry.
The Metastatic Microenvironment: Melanoma-Microglia Cross-Talk Promotes the Malignant Phenotype of Melanoma Cells.
The tumour suppressor p33ING1 does not regulate migration and angiogenesis in melanoma cells.
TIMP-2 expression modulates human melanoma cell adhesion and motility.
TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase.
TIMP-2: identification and characterization of a new member of the metalloproteinase inhibitor family.
Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis.
Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines.
Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family.
Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues.
Tissue Rebuilding During Spontaneous Regression of Melanoma in the Melanoma-bearing Libechov Minipig.
TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness.
TNF-alpha increases human melanoma cell invasion and migration in vitro: the role of proteolytic enzymes.
Transcriptional regulation of metastasis-related genes in human melanoma.
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion.
Up-regulating ribonuclease inhibitor inhibited epithelial-to-mesenchymal transition and metastasis in murine melanoma cells.
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Wild-type p53 gene transfer inhibits invasion and reduces matrix metalloproteinase-2 levels in p53-mutated human melanoma cells.
Zwint facilitates melanoma progression by promoting c-Myc expression.
[4-acetamidophenyl retinoate (4-APR) inhibits reconstituted basement membrane invasion by tumor cells and its mechanism]
[Correlation between the biological behavior and invasion potential in three mouse melanoma cell lines]
[Role of matrix metalloproteinases (MMPs) in tumor invasion and metastasis: serial studies on MMPs and TIMPs]
[The influence of different microenvironments on melanoma invasiveness and microcirculation patterns]
[The mechanisms of microenvironments influence on vasculogenic mimicry between introcular and subcutaneous melanoma]
Melanoma, Experimental
Differences in expression of metalloproteinases and plasminogen activators in murine melanocytes and B16 melanoma variants: lack of association with in vitro invasion.
Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines.
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin A chain.
Melkersson-Rosenthal Syndrome
Expression of protease-activated receptor-1 and -2 in orofacial granulomatosis.
Meningeal Carcinomatosis
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Meningioma
Correlation of clinical and biological parameters with peritumoral edema in meningioma.
Differential expression of extracellular matrix-related genes in rare variants of meningioma.
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.
Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas.
Expression of extracellular matrix-degrading proteins in classic, atypical, and anaplastic meningiomas.
Expression of matrix metalloproteinases 2 and 9 in meningiomas associated with different degrees of brain invasiveness and edema.
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Expression of MMP-2 and -9 in short-term cultures of meningioma: influence of histological subtype.
Expression of MMP-2 and MMP-9 in Benign Canine Rostrotentorial Meningiomas Is Not Correlated to the Extent of Peritumoral Edema.
Gene Expression of Matrix Metalloproteinases and their Inhibitors (TIMPs) in Meningiomas of Dogs.
Increased expression of avian erythroblastosis virus E26 oncogene homolog 1 in World Health Organization grade 1 meningiomas is associated with an elevated risk of recurrence and is correlated with the expression of its target genes matrix metalloproteinase-2 and MMP-9.
Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 expression in the biological behavior of Canine and Feline Meningioma.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 expressions correlate with the recurrence of intracranial meningiomas.
Possible role of matrix metalloproteinase in osteolytic intracranial meningiomas.
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Presence of matrix metalloproteinase-2 and tissue inhibitor matrix metalloproteinase-2 gene polymorphisms and immunohistochemical expressions in intracranial meningiomas.
The effects of exogenous growth factors on matrix metalloproteinase secretion by human brain tumour cells.
The role of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in microcystic meningiomas.
Meningitis
Association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis.
Association of matrix metalloproteinase-9 in eosinophilic meningitis of BALB/c mice caused by Angiostrongylus cantonensis.
Effects of purulent meningitis on the changes of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase inhibitor-1 (TIMP-1) in cerebrospinal fluid of neonates.
Expression of MMP-2 and TIMP-1 in cerebrospinal fluid and the correlation with dynamic changes of serum PCT in neonatal purulent meningitis.
Gelatinase activity of matrix metalloproteinases in the cerebrospinal fluid of various patient populations.
Induction of matrix metalloproteinase-9 in murine eosinophilic meningitis caused by Angiostrongylus cantonensis.
Marked increase of matrix metalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculous meningoencephalitis.
Matrix metalloprotease-9 in cerebrospinal fluid correlates with disease activity in lymphomatous meningitis.
Serum Matrix Metalloproteinase-2 Levels Indicate Blood-CSF Barrier Damage in Patients with Infectious Meningitis.
Meningitis, Aseptic
Persistent increase of matrix metalloproteinases in cerebrospinal fluid of tuberculous meningitis.
Meningitis, Bacterial
Dexamethasone regulation of matrix metalloproteinase expression in experimental pneumococcal meningitis.
Experimental pneumococcal meningitis in rabbits: the increase of matrix metalloproteinase-9 in cerebrospinal fluid correlates with leucocyte invasion.
Immunohistochemical analysis of MMP-9, MMP-2 and TIMP-1, TIMP-2 expression in the central nervous system following infection with viral and bacterial meningitis.
Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae.
Serum Matrix Metalloproteinase-2 Levels Indicate Blood-CSF Barrier Damage in Patients with Infectious Meningitis.
Meningitis, Pneumococcal
Dexamethasone regulation of matrix metalloproteinase expression in experimental pneumococcal meningitis.
Inhibition of matrix metalloproteinases-2 and -9 prevents cognitive impairment induced by pneumococcal meningitis in Wistar rats.
Meningitis, Viral
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in viral meningitis: upregulation of MMP-9 and TIMP-1 in cerebrospinal fluid.
Menorrhagia
Menstrual activity of matrix metalloproteinases is decreased in endometrium regenerating after thermal ablation.
Reduced levels of VEGF-A and MMP-2 and MMP-9 activity and increased TNF-alpha in menstrual endometrium and effluent in women with menorrhagia.
Mesothelioma
3-O-Methylfunicone, a metabolite produced by Penicillium pinophilum, modulates ERK1/2 activity, affecting cell motility of human mesothelioma cells.
Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.
ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: A comparison between mesothelioma and mesothelial cells.
Inhibition of mesothelioma cell growth in vitro by doxycycline.
Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion.
Mesothelioma, Malignant
3-D collagen-dependent cell surface expression of MT1-MMP and MMP-2 activation regardless of integrin ?1 function and matrix stiffness.
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Regulation of matrix metalloprotease activity in malignant mesothelioma cell lines by growth factors.
Metabolic Syndrome
Adiponectin predicts MMP-2 activity independently of obesity.
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
MMPs 2 and 9 are essential for coronary collateral growth and are prominently regulated by p38 MAPK.
Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.
Vitamin D supplementation has no effect on matrix metalloproteinases-2, -9, and tissue inhibitor matrix metalloproteinase-1 in subjects with metabolic syndrome: A pilot study.
Metrorrhagia
Differential elevation of matrix metalloproteinase expression in women exposed to levonorgestrel-releasing intrauterine system for a short or prolonged period of time.
Migraine Disorders
Acupuncture decreases matrix metalloproteinase-2 activity in patients with migraine.
Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura.
New implications of the proteolytic balance between matrix metalloproteinases and their tissue inhibitors in migraine with and without aura.
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Migraine with Aura
Matrix metalloproteinase (MMP)-2 gene polymorphisms affect circulating MMP-2 levels in patients with migraine with aura.
Migraine without Aura
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Mitral Valve Insufficiency
[Involvement of matrix metalloproteinases in the regulation of myocardial extracellular matrix in patients with congestive heart failure]
Mitral Valve Prolapse
Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease.
Investigation of the Matrix Metalloproteinase-2 Gene in Patients with Non-Syndromic Mitral Valve Prolapse.
Mouth Neoplasms
Antimetastatic effects of Eclipta prostrata extract on oral cancer cells.
Antimetastatic effects of Rheum palmatum L. extract on oral cancer cells.
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Assessment of MicroRNA (miR)-365 Effects on Oral Squamous Carcinoma Cell Line Phenotypes.
Caffeic Acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-activated protein kinase pathway.
Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma.
Clinical significance of MMP-2 and MMP-9 in patients with oral cancer.
Coexpression of growth differentiation factor 11 and reactive oxygen species in metastatic oral cancer and its role in inducing the epithelial to mesenchymal transition.
Combined evaluation of matrix metalloproteinases and their inhibitors has better clinical utility in oral cancer.
Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression.
Corrigendum to "Caffeic Acid Phenethyl Ester Inhibits Oral Cancer Cell Metastasis by Regulating Matrix Metalloproteinase-2 and the Mitogen-Activated Protein Kinase Pathway".
Curcumin Inhibits Invasiveness and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Through Reducing Matrix Metalloproteinase 2, 9 and Modulating p53-E-Cadherin Pathway.
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity.
Duchesnea indica extract attenuates oral cancer cells metastatic potential through the inhibition of the matrix metalloproteinase-2 activity by down-regulating the MEK/ERK pathway.
Epigallocatechin-3-gallate inhibits the invasion of human oral cancer cells and decreases the productions of matrix metalloproteinases and urokinase-plasminogen activator.
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Gallic acid inhibits migration and invasion of SCC-4 human oral cancer cells through actions of NF-?B, Ras and matrix metalloproteinase-2 and -9.
Geraniin inhibits oral cancer cell migration by suppressing matrix metalloproteinase-2 activation through the FAK/Src and ERK pathways.
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Inhibition of gelatinase activity by cyclic peptides--A support for oral cancer treatment?
Kaempferol reduces matrix metalloproteinase-2 expression by down-regulating ERK1/2 and the activator protein-1 signaling pathways in oral cancer cells.
Luteolin-7-O-Glucoside Inhibits Oral Cancer Cell Migration and Invasion by Regulating Matrix Metalloproteinase-2 Expression and Extracellular Signal-Regulated Kinase Pathway.
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Matrix metalloproteinase-13 is a target gene of high-mobility group box-containing protein 1 in modulating oral cancer cell invasion.
Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer.
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Paclitaxel induces apoptosis and reduces proliferation by targeting epidermal growth factor receptor signaling pathway in oral cavity squamous cell carcinoma.
Phenethyl isothiocyanate suppresses EGF-stimulated SAS human oral squamous carcinoma cell invasion by targeting EGF receptor signaling.
Pinostilbene Hydrate Suppresses Human Oral Cancer Cell Metastasis by Downregulation of Matrix Metalloproteinase-2 Through the Mitogen-Activated Protein Kinase Signaling Pathway.
Pinosylvin reduced migration and invasion of oral cancer carcinoma by regulating matrix metalloproteinase-2 expression and extracellular signal-regulated kinase pathway.
Pterostilbene suppresses oral cancer cell invasion by inhibiting MMP-2 expression.
Quercetin inhibits cell viability, migration and invasion by regulating miR-16/HOXA10 axis in oral cancer.
RNAi targeting urokinase-type plasminogen activator receptor inhibits metastasis and progression of oral squamous cell carcinoma in vivo.
Rubus idaeus extract suppresses migration and invasion of human oral cancer by inhibiting MMP-2 through modulation of the Erk1/2 signaling pathway.
Senescent cancer-associated fibroblasts secrete active MMP-2 that promotes keratinocyte dis-cohesion and invasion.
Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.
Moyamoya Disease
Increased expression of serum matrix metalloproteinase-9 in patients with moyamoya disease.
The GC?+?CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2 is genetic predisposing factors for prevalence of moyamoya disease.
Mucocele
Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
Mucocutaneous Lymph Node Syndrome
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
[Roles of matrix metalloproteinases, tissue inhibitor of matrix metalloproteinase and hs-CRP in Kawasaki disease]
Mucopolysaccharidoses
Spectrum of common and uncommon causes of knee joint hyaline cartilage degeneration and their key imaging features.
Mucositis
Correction: olmesartan decreased levels of IL-1? and TNF-?, down-regulated MMP-2, MMP-9, COX-2, RANK/RANKL and up-regulated SOCs-1 in an intestinal mucositis model.
Olmesartan decreased levels of IL-1? and TNF-?, down-regulated MMP-2, MMP-9, COX-2, RANK/RANKL and up-regulated SOCs-1 in an intestinal mucositis model.
Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1?, IL-10, RANK, OPG, MMP-2, TGF-? and TNF-?: follow-up over 5 years.
Multiple Myeloma
Antimyeloma effects of resveratrol through inhibition of angiogenesis.
Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma.
Cell-surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases.
Designing new generation of potent inhibitors against membrane-type matrix metalloproteinase-2: a computational effort against multiple myeloma.
Effect of wild type PTEN gene on proliferation and invasion of multiple myeloma.
Increased expression of metalloproteinase-2 and -9 (MMP-2, MMP-9), tissue inhibitor of metalloproteinase-1 and -2 (TIMP-1, TIMP-2), and EMMPRIN (CD147) in multiple myeloma.
Matrix metalloproteinases-1 and -2, and tissue inhibitor of metalloproteinase-2 production is abnormal in bone marrow stromal cells of multiple myeloma patients.
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment.
The evaluation of angiogenesis and matrix metalloproteinase-2 secretion in bone marrow of multiple myeloma patients before and after the treatment.
Multiple Sclerosis
Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis.
Anti-inflammatory nutritional intervention in patients with relapsing-remitting and primary-progressive multiple sclerosis: A pilot study.
Association of MMP-2 (?1306 C/T) Gene Polymorphism with Predisposition to Optic Neuritis and Optic Neuritis Together with Multiple Sclerosis.
Biomarkers for diagnosing and monitoring autoimmune diseases.
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Functional Promoter Polymorphisms of MMP-2 C-735T and MMP-9 C-1562T and Their Synergism with MMP-7 A-181G in Multiple Sclerosis.
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.
Gelatinases (MMP-2 and MMP-9) are preferentially expressed by Th1 vs. Th2 cells.
Heterogeneity of serum gelatinases MMP-2 and MMP-9 isoforms and charge variants.
Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis.
Interplay between Matrix Metalloproteinase-9, Matrix Metalloproteinase-2, and Interleukins in Multiple Sclerosis Patients.
Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-?s, Claudin-11, and Matrix Metalloproteinase-2.
Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis.
Matrix metalloproteinase-9 and matrix metalloproteinase-2 as biomarkers of various courses in multiple sclerosis.
Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis.
Modulation of monocytes matrix metalloproteinase-2, MT1-MMP and TIMP-2 by interferon-gamma and -beta: implications to multiple sclerosis.
Modulation of proteoglycan receptor PTP? enhances MMP-2 activity to promote recovery from multiple sclerosis.
Multiple sclerosis: Association of gelatinase B/matrix metalloproteinase-9 with risk and clinical course the disease.
Neutralizing antibodies against IFN-beta in multiple sclerosis: antagonization of IFN-beta mediated suppression of MMPs.
PECAM-1 and gelatinase B coexist in vascular cuffs of multiple sclerosis lesions.
Potential relevance of cerebrospinal fluid and serum levels and intrathecal synthesis of active matrix metalloproteinase-2 (MMP-2) as markers of disease remission in patients with multiple sclerosis.
Proinflammatory cytokines and matrix metalloproteinases in CSF of patients with VZV vasculopathy.
Serum gelatinase B/MMP-9 in primary progressive multiple sclerosis patients treated with interferon-beta-1a.
Serum levels of matrix metalloproteinase-2, -9, and vitamin D in patients with multiple sclerosis with or without herpesvirus-6 seropositivity.
Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes.
Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: relationships with different magnetic resonance imaging measures of disease activity during IFN-beta-1a treatment.
The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
Multiple Sclerosis, Chronic Progressive
Serum gelatinase B/MMP-9 in primary progressive multiple sclerosis patients treated with interferon-beta-1a.
Multiple Sclerosis, Relapsing-Remitting
Anti-inflammatory nutritional intervention in patients with relapsing-remitting and primary-progressive multiple sclerosis: A pilot study.
Influence of combined functional resistance and endurance exercise over 12?weeks on matrix metalloproteinase-2 serum concentration in persons with relapsing-remitting multiple sclerosis - a community-based randomized controlled trial.
Muscle Cramp
LL-37 as a therapeutic target for late stage prostate cancer.
Muscular Atrophy
Electrical Stimulation of Denervated Rat Skeletal Muscle Retards Capillary and Muscle Loss in Early Stages of Disuse Atrophy.
Emerging Ideas: Matrix Metalloproteinase-2 in Muscle Atrophy.
Matrix metalloproteinase-2 expression and promoter/enhancer activity in skeletal muscle atrophy.
Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy.
Role of gelatinases in disuse-induced skeletal muscle atrophy.
Muscular Diseases
Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx muscles reduces angiogenesis resulting in impaired growth of regenerated muscle fibers.
MMP-10 is required for efficient muscle regeneration in mouse models of injury and muscular dystrophy.
Muscular Dystrophies
Activation and localization of matrix metalloproteinase-2 and -9 in the skeletal muscle of the muscular dystrophy dog (CXMDJ).
Metalloproteinase expression is altered in cardiac and skeletal muscle in cancer cachexia.
The enzymatic processing of ?-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site.
Muscular Dystrophy, Duchenne
Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx muscles reduces angiogenesis resulting in impaired growth of regenerated muscle fibers.
MMP-10 is required for efficient muscle regeneration in mouse models of injury and muscular dystrophy.
Myasthenia Gravis
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Serum levels of matrix metalloproteinases: implications in clinical neurology.
Mycetoma
Active Matrix Metalloprotease-9 Is Associated with the Collagen Capsule Surrounding the Madurella mycetomatis Grain in Mycetoma.
Mycosis Fungoides
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Myelitis, Transverse
Cytokines and matrix metalloproteinases in the cerebrospinal fluid of patients with acute transverse myelitis: an outcome analysis.
Myelodysplastic Syndromes
Reduced expression of inducible gelatinase B/matrix metalloproteinase-9 in monocytes from patients with myelodysplastic syndrome: Correlation of inducible levels with the percentage of cytogenetically marked cells and with marrow cellularity.
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Myocardial Infarction
Association of matrix metalloproteinase-2 gene promoter polymorphism with myocardial infarction susceptibility in a Mexican population.
Change in matrix metalloproteinase 2, 3, and 9 levels at the time of and after acute atherothrombotic myocardial infarction.
Circulating level of gelatinase activity predicts ventricular remodeling in patients with acute myocardial infarction.
Correlation between acute myocardial infarction complicated with cerebral infarction and expression levels of MMP-2 and MMP-9.
Correlation between plasma angiopoietin-1, angiopoietin-2 and matrix metalloproteinase-2 in coronary heart disease.
Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection.
Differential regulation of matrix metalloproteinase-2 and -9 expression and activity in adult rat cardiac fibroblasts in response to interleukin-1beta.
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction.
Effect of Ginkgo biloba extract on experimental cardiac remodeling.
Effect of typhaneoside on ventricular remodeling and regulation of PI3K/Akt/mTOR pathway.
Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and -9, and their inhibitors, tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2.
EMMPRIN-Targeted Magnetic Nanoparticles for In Vivo Visualization and Regression of Acute Myocardial Infarction.
Enhanced cardiac production of matrix metalloproteinase-2 and -9 and its attenuation associated with pravastatin treatment in patients with acute myocardial infarction.
Enhanced matrix metalloproteinase activity in skeletal muscles of rats with congestive heart failure.
Enhancement of Matrix Metalloproteinase 2 and 9 Inhibitory Action of Minocycline by Aspirin: An Approach to Attenuate Outcome of Acute Myocardial Infarction in Diabetes.
Evaluation of (68)Ga-labeled peptide tracer for detection of gelatinase expression after myocardial infarction in rat.
Expressions and clinical significance of factors related to acute coronary syndrome.
Influence of interleukin-1 beta gene polymorphisms on the risk of myocardial infarction and ischemic stroke at young age in vivo and in vitro.
Intracellular Regulation of Matrix Metalloproteinase-2 Activity: New Strategies in Treatment and Protection of Heart Subjected to Oxidative Stress.
Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison With Intramyocardial Cell Delivery.
Matrix Metalloproteinase-2 Is Activated During Ischemia/Reperfusion in a Model of Myocardial Infarction.
Matrix Metalloproteinase-2 predicts mortality in patients with acute coronary syndrome.
Matrix metalloproteinases in patients with myocardial infarction and percutaneous revascularization.
MMP-2: Is too low as bad as too high in the cardiovascular system?
Noninvasive Limb Ischemic Preconditioning Protects Against Myocardial I/R Injury in Rats.
Osthole ameliorates acute myocardial infarction in rats by decreasing the expression of inflammatory-related cytokines, diminishing MMP-2 expression and activating p-ERK.
Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes.
Plasma MMP-2, MMP-9 and N-BNP in long-term survivors following complicated myocardial infarction: relation to cardiac magnetic resonance imaging measures of left ventricular structure and function.
Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.
Pravastatin suppresses the increase in matrix metalloproteinase-2 levels after acute myocardial infarction.
Predictive utility of the changes in matrix metalloproteinase-2 in the early phase for left ventricular reverse remodeling after an acute myocardial infarction.
Selective spatiotemporal induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 transcription after myocardial infarction.
Serum levels of matrix metalloproteinases 2 and 9 in patients with acute myocardial infarction.
Serum metalloproteinase 9 levels in patients with coronary artery disease: a novel marker of inflammation.
Serum MMP-9 activity as a diagnosing marker for the developing heart failure of post MI patients.
Serum profiles of matrix metalloproteinases and their tissue inhibitor in patients with acute coronary syndromes. The effects of short-term atorvastatin administration.
Sesamol Attenuates Isoproterenol-induced Acute Myocardial Infarction via Inhibition of Matrix Metalloproteinase-2 and -9 Expression in Rats.
Sustained Release of a Peptide-Based Matrix Metalloproteinase-2 Inhibitor to Attenuate Adverse Cardiac Remodeling and Improve Cardiac Function Following Myocardial Infarction.
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice.
The p66ShcA adaptor protein regulates healing after myocardial infarction.
The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction.
Trimetazidine suppresses oxidative stress, inhibits MMP-2 and MMP-9 expression, and prevents cardiac rupture in mice with myocardial infarction.
Vitamin D is related to markers of vulnerable plaque in acute myocardial infarction.
[Analysis of the gene polymorphism of matrix metalloproteinase-2 and -9 in patients with coronary heart disease]
[Correlation between serum MMP-2 and MMP-9 in patients with acute myocardial infarction before and after PCI.]
Myocardial Ischemia
Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity.
Enhancement of Matrix Metalloproteinase 2 and 9 Inhibitory Action of Minocycline by Aspirin: An Approach to Attenuate Outcome of Acute Myocardial Infarction in Diabetes.
Inhibition of CD34+ cell migration by matrix metalloproteinase-2 during acute myocardial ischemia, counteracted by ischemic preconditioning.
Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury.
Matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes.
Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.
[Correlation between serum MMP-2 and MMP-9 in patients with acute myocardial infarction before and after PCI.]
Myocardial Reperfusion Injury
Role of Metalloproteinases and Tissue Inhibitors of Metalloproteinases During Cardiopulmonary Bypass in Rats.
Myocardial Stunning
Duration of ischaemia determines matrix metalloproteinase-2 activation in the reperfused rabbit heart.
Myocarditis
Carvedilol Inhibits Matrix Metalloproteinase-2 Activation in Experimental Autoimmune Myocarditis: Possibilities of Cardioprotective Application.
Increased activities of cardiac matrix metalloproteinases matrix metalloproteinase (MMP)-2 and MMP-9 are associated with mortality during the acute phase of experimental Trypanosoma cruzi infection.
Matrix metalloproteinase (MMP)-9, but not MMP-2, is involved in the development and progression of C protein-induced myocarditis and subsequent dilated cardiomyopathy.
Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy.
[Experimental study of MMP-2 inhibitor treatment of experimental autoimmune myocarditis in Lewis rats].
Myoma
Effects of ionizing radiation and HPSE1 inhibition on the invasion of oral tongue carcinoma cells on human extracellular matrices in vitro.
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
In vivo mechanisms of uterine myoma volume reduction with ulipristal acetate treatment.
Matrix metalloproteinase activity correlates with uterine myoma volume reduction after ulipristal acetate treatment.
Myopathy, Central Core
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.
Myopia
Assessment of the association of matrix metalloproteinases with myopia, refractive error and ocular biometric measures in an Australian cohort.
Association between MMP/TIMP Levels in the Aqueous Humor and Plasma with Axial Lengths in Myopia Patients.
Cause and Effect Relationship between Changes in Scleral Matrix Metallopeptidase-2 Expression and Myopia Development in Mice.
Changes in scleral MMP-2, TIMP-2 and TGFbeta-2 mRNA expression after imposed myopic and hyperopic defocus in chickens.
Changes of TGF-?2, MMP-2, and TIMP-2 levels in the vitreous of patients with high myopia.
DNA methylation and mRNA expression of IGF-1 and MMP-2 after form-deprivation myopia in guinea pigs.
Effects of hepatocyte growth factor on MMP-2 expression in scleral fibroblasts from a guinea pig myopia model.
Effects of lumican expression on the apoptosis of scleral fibroblasts: In vivo and in vitro experiments.
Evaluation of MMP2 as a candidate gene for high myopia.
Expression and cDNA sequence of matrix metalloproteinase-2 (MMP-2) in a mammalian model of human disease processes: Tupaia belangeri.
Form-deprivation myopia induces activation of scleral matrix metalloproteinase-2 in tree shrew.
Gelatinase A and TIMP-2 expression in the fibrous sclera of myopic and recovering chick eyes.
Genipin inhibits the scleral expression of miR-29 and MMP2 and promotes COL1A1 expression in myopic eyes of guinea pigs.
Human aqueous humor levels of transforming growth factor-?2: Association with matrix metalloproteinases/tissue inhibitors of matrix metalloproteinases.
Increased latent gelatinase activity in the sclera of visually deprived chicks.
MMP-2 participates in the sclera of guinea pig with form-deprivation myopia via IGF-1/STAT3 pathway.
MMP-2, MMP-3, TIMP-1, TIMP-2, and TIMP-3 protein levels in human aqueous humor: relationship with axial length.
Oral Bovine Milk Lactoferrin Administration Suppressed Myopia Development through Matrix Metalloproteinase 2 in a Mouse Model.
Pirenzepine Inhibits Myopia in Guinea Pig Model by Regulating the Balance of MMP-2 and TIMP-2 Expression and Increased Tyrosine Hydroxylase Levels.
Reduced Scleral TIMP-2 Expression Is Associated With Myopia Development: TIMP-2 Supplementation Stabilizes Scleral Biomarkers of Myopia and Limits Myopia Development.
Regulation of Matrix Metalloproteinase-2 Secretion from Scleral Fibroblasts and Retinal Pigment Epithelial Cells by miR-29a.
Systematic investigation of the relationship between high myopia and polymorphisms of the MMP2, TIMP2 and TIMP3 genes by a DNA pooling approach.
The expression of cytokines in aqueous humor of high myopic patients with cataracts.
Up-Regulation of Matrix Metalloproteinase-2 by Scleral Monocyte-Derived Macrophages Contributes to Myopia Development.
[Dynamic changes of MMP-2 activity in the posterior sclera of chicks with form-deprivation myopia]
[Effect of pirenzepine on form deprivation myopia in chicks and its possible mechanism]
[Expressions of collagen , matrix metalloproeinases-2, and tissue inhibitor of matrix metalloproteinase-2 in the posterior sclera of newborn guinea pigs with negative lens-defocused myopia]
[Matrix metalloproteinase-2 mRNA expression in the posterior sclera of chick form-deprivation myopia]
Myositis
Matrix metalloproteinases in inflammatory myopathies: enhanced immunoreactivity near atrophic myofibers.
Myxoma
Expression of MMP-2 and MMP-9 in odontogenic myxoma in a child: report of a clinical case.
Immunohistochemical expression of matrix metalloproteinases 1, 2, and 9 in odontogenic myxoma and dental germ papilla.
The expression of apoptotic proteins and matrix metalloproteinases in odontogenic myxomas.
Nasal Polyps
Double-stranded RNA poly(I:C) enhances matrix metalloproteinase mRNA expression in human nasal polyp epithelial cells.
Eosinophil inflammation of nasal polyp tissue: relationships with matrix metalloproteinases, tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta1.
Expression of matrix metalloproteinase 2 and 9 and tissue inhibitor of metalloproteinase 1 in nonrecurrent vs recurrent nasal polyps.
Expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in recurrent chronic rhinosinusitis with nasal polyposis.
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Expression of metalloproteinases MMP-2 and MMP-9 in antrochoanal polyps.
Increased expression of matrix metalloproteinase-2 in nasal polyps.
Increased expression of matrix metalloproteinase-9 in nasal polyps.
Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs.
Matrix metalloproteinase-2 gene polymorphisms in nasal polyps.
Matrix metalloproteinases and their impact on sinusal extension in chronic rhinosinusitis with nasal polyps.
Nonasthmatic nasal polyposis patients with allergy exhibit greater epithelial MMP positivity.
Polymorphisms in chronic rhinosinusitis with nasal polyps - a systematic review.
Relationship between matrix metalloproteinases MMP-2, MMP-9, tissue inhibitor of matrix metalloproteinases-1 and IL-5, IL-8 in nasal polyps.
Rhinovirus upregulates matrix metalloproteinase-2, matrix metalloproteinase-9, and vascular endothelial growth factor expression in nasal polyp fibroblasts.
Suppression of matrix metalloproteinase production from nasal fibroblasts by fluticasone propionate in vitro.
The role of MMP-2, MMP-9, and TIMP-1 in the pathogenesis of nasal polyps: Immunohistochemical assessment at eight different levels in the epithelial, subepithelial, and deep layers of the mucosa.
Vitamin D decreases the secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 in fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyposis.
[Effects of double-stranded RNA poly(I:C) on matrix metalloproteinase mRNA expression in human nasal polyp epithelial cells]
Nasopharyngeal Carcinoma
A single nucleotide polymorphism in the matrix metalloproteinase 2 promoter is closely associated with high risk of nasopharyngeal carcinoma in Cantonese from southern China.
Clinicopathologic significance of plasma matrix metalloproteinase-2 and -9 levels in patients with undifferentiated nasopharyngeal carcinoma.
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinoma.
Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity.
Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion.
Effect of WNT5A on epithelial-mesenchymal transition and its correlation with tumor invasion and metastasis in nasopharyngeal carcinoma.
Epigallocatechin-3-gallate inhibits migration of human nasopharyngeal carcinoma cells by repressing MMP-2 expression.
Evodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression.
IL-6/NOS2 inflammatory signals regulate MMP-9 and MMP-2 activity and disease outcome in nasopharyngeal carcinoma patients.
Interleukin-6 promotes the migration and invasion of nasopharyngeal carcinoma cell lines and upregulates the expression of MMP-2 and MMP-9.
Matrix metalloproteinase 2 contributes to aggressive phenotype, epithelial-mesenchymal transition and poor outcome in nasopharyngeal carcinoma.
Morusin Suppresses Cancer Cell Invasion and MMP-2 Expression through ERK Signaling in Human Nasopharyngeal Carcinoma.
Nobiletin inhibits invasion and migration of human nasopharyngeal carcinoma cell lines by involving ERK1/2 and transcriptional inhibition of MMP-2.
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells.
Pinostilbene Hydrate Inhibits the Migration and Invasion of Human Nasopharyngeal Carcinoma Cells by Downregulating MMP-2 Expression and Suppressing Epithelial-Mesenchymal Transition Through the Mitogen-Activated Protein Kinase Signaling Pathways.
Regulation of matrix metalloproteinase-1 by Epstein-Barr virus proteins.
Rubus idaeus Inhibits Migration and Invasion of Human Nasopharyngeal Carcinoma Cells by Suppression of MMP-2 through Modulation of the ERK1/2 Pathway.
Salvianolic acid A suppresses MMP-2 expression and restrains cancer cell invasion through ERK signaling in human nasopharyngeal carcinoma.
The association between gene polymorphisms and risk of nasopharyngeal carcinoma.
Tissue inhibitor of matrix metalloproteinase-2 in nasopharyngeal carcinoma.
Use of nimotuzumab combined with cisplatin in treatment of nasopharyngeal carcinoma and its effect on expressions of VEGF and MMP-2.
Vascular endothelial growth factor165-regulated nasopharyngeal carcinoma cell lines invasion and migration involve expression and activation of matrix metalloproteinase-2.
Zoledronic acid inhibits proliferation and impairs migration and invasion through downregulating VEGF and MMPs expression in human nasopharyngeal carcinoma cells.
[Effect of macrophage migration inhibitory factor (MIF) on expression of MMP-2,MMP-9,and IL-8 in nasopharyngeal carcinoma cell strains]
[Expressions of COX-2 and MMP-2 in nasopharyngeal carcinoma and the their relationship with lymph node metastasis]
Nasopharyngeal Neoplasms
Contribution of Matrix Metalloproteinase-2 Promoter Genotypes to Nasopharyngeal Cancer Susceptibility and Metastasis in Taiwan.
Dione-thiophene conjugate inhibits proliferation and metastasis of nasopharyngeal carcinoma cells through calcium binding protein-P down-regulation.
Neoplasm Metastasis
'Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer'.
(-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis.
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
(-)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats.
(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone.
(±)Equol inhibits invasion in prostate cancer DU145 cells possibly via down-regulation of matrix metalloproteinase-9, matrix metalloproteinase-2 and urokinase-type plasminogen activator by antioxidant activity.
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione inhibits the growth and metastasis of breast carcinoma in mice.
3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NF?B Signaling Pathways.
3,5-Dicaffeoyl-epi-quinic acid inhibits the PMA-stimulated activation and expression of MMP-9 but not MMP-2 via downregulation of MAPK pathway.
?-Elemene inhibits the metastasis of B16F10 melanoma cells by downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9.
?-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells.
A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide.
A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of alpha1beta1, alpha4beta1 and alpha6beta1 integrins.
A dual-functional magnetic microsphere for ICP-MS quantification and fluorescence imaging of matrix metalloproteinase 2 in cell secretion.
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.
A matrix metalloproteinase expressed on the surface of invasive tumour cells.
A Multi-functional Vector for delivery of Genome Editing Plasmid Targeting ?-Catenin to Re-modulate Cancer Cell Properties.
A multiplicity of anti-invasive effects of farnesyl transferase inhibitor SCH66336 in human head and neck cancer.
A novel bisindole-PBD conjugate inhibits angiogenesis by regulating STAT3 and VEGF in breast cancer cells.
A novel function of syndecan-2, suppression of matrix metalloproteinase-2 activation, which causes suppression of metastasis.
A Novel Role of Cab45-G in Mediating Cell Migration in Cancer Cells.
A Novel Synthetic Compound (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile Inhibits TNF?-Induced MMP9 Expression via EGR-1 Downregulation in MDA-MB-231 Human Breast Cancer Cells.
A novel tripeptide, tyroserleutide, inhibits irradiation-induced invasiveness and metastasis of hepatocellular carcinoma in nude mice.
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice.
A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
A randomized, phase II trial of ketoconazole plus alendronate versus ketoconazole alone in patients with androgen independent prostate cancer and bone metastases.
A role for PI3K-Akt signaling in pulmonary metastatic nodule formation of the osteosarcoma cell line, LM8.
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis.
Accumulation of extracellular matrix in the liver induces high metastatic potential of hepatocellular carcinoma to the lung.
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice.
Actin cytoskeleton participation in the onset of IL-1beta induction of an invasive mesenchymal-like phenotype in epithelial MCF-7 cells.
Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways.
Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity.
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.
Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2).
Activation of Stat3 in Human Melanoma Promotes Brain Metastasis.
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma.
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
Ad.mda-7 (IL-24) selectively induces apoptosis in hepatocellular carcinoma cell lines, suppresses metastasis, and enhances the effect of doxorubicin on xenograft tumors.
Adaptation to chronic acidic extracellular pH elicits a sustained increase in lung cancer cell invasion and metastasis.
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
ALCAM/CD166: cancer-related issues.
Alpha-chaconine-reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells.
alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells.
Alpha-mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway.
Alterations in enhancer of zeste homolog 2, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression are associated with ex vivo and in vitro bone metastasis in renal cell carcinoma.
Alterations of metastasis-related genes identified using an oligonucleotide microarray of genistein-treated HCC1395 breast cancer cells.
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Aluminum naphthalocyanine conjugate as an MMP-2-activatable photoacoustic probe for in vivo tumor imaging.
Amentoflavone Inhibits Experimental Tumor Metastasis Through a Regulatory Mechanism Involving MMP-2, MMP-9, Prolyl Hydroxylase, Lysyl Oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and Cytokines in Lung Tissues of C57BL/6 Mice.
Amplification of MMP-2 and MMP-9 production by prostate cancer cell lines via activation of protease-activated receptors.
An essential role for N-cadherin and beta-catenin for progression in tongue squamous cell carcinoma and their effect on invasion and metastasis of Tca8113 tongue cancer cells.
An in vivo model for screening peptidomimetic inhibitors of gelatinase A.
An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines.
An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment.
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Analysis of matrix metalloproteinase mRNAs expressed in hepatocellular carcinoma cell lines.
Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer.
Annexin A3 Knockdown Suppresses Lung Adenocarcinoma.
Anthocyanins from Black Rice (Oryza sativa L.) Demonstrate Antimetastatic Properties by Reducing MMPs and NF-?B Expressions in Human Oral Cancer CAL 27 Cells.
Anti-cancer effect of metformin on the metastasis and invasion of primary breast cancer cells through mediating NF-kB activity.
Anti-endometriosis Mechanism of Jiawei Foshou San Based on Network Pharmacology.
Anti-inflammatory and anticancer effects of p-methoxycinnamic acid, an active phenylpropanoid, against 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
Anti-Metastatic Effects of Antrodan with and without Cisplatin on Lewis Lung Carcinomas in a Mouse Xenograft Model.
Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases.
Anticancer effects of tanshinone I in human non-small cell lung cancer.
Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line.
Anticancer Efficacy of Polyphenols and Their Combinations.
Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226.
Antimetastatic activity of novel ruthenium (III) pyridine complexes.
Antimetastatic and anti-invasive ability of phospho-ascorbyl palmitate through intracellular ascorbate enrichment and the resultant antioxidant action.
Antimetastatic effects of Eclipta prostrata extract on oral cancer cells.
Antimetastatic Potentials of Phyllanthusurinaria L on A549 and Lewis Lung Carcinoma Cells via Repression of Matrix-Degrading Proteases.
Antineoplastic activity of Newcastle disease virus strain D90 in oral squamous cell carcinoma.
Antineoplastic effect of intracellular expression of a single-chain antibody directed against type IV collagenase.
Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma.
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Antitumor effects of the molecule-downsized immunoconjugate composed of lidamycin and Fab' fragment of monoclonal antibody directed against type IV collagenase.
Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-?B and AP-1 signaling pathways in DU145 human prostate cancer cells.
Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.
Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma.
Antitumor evaluation of carboxymethyl chitosan based norcantharidin conjugates against gastric cancer as novel polymer therapeutics.
Apigenin Attenuates Insulin-Like Growth Factor-I Signaling in an Autochthonous Mouse Prostate Cancer Model.
Apoptotic Induction and Anti-Migratory Effects of Rhazya Stricta Fruit Extracts on a Human Breast Cancer Cell Line.
Aquaporin 1 promotes the proliferation and migration of lung cancer cell in vitro.
Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors.
Assay of matrix metalloproteinases types 1, 2, 3 and 9 in breast cancer.
Assessment of indirect hemagglutination and zymography procedures in evaluation of gelatinase a in patients with benign and malignant prostate hyperplasia.
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Association between Expression of Tissue Inhibitors of Metalloproteinases-1, Matrix Metalloproteinase-2, and Matrix Metalloproteinase-9 Genes and Axillary Lymph Nodes Metastasis in Patients with Breast Cancer.
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer.
Association of matrix metalloproteinase (MMP)-2 and -9 expression with extra-gastrointestinal stromal tumor metastasis.
Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.
Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.
Association of MMP-2 expression and prognosis in osteosarcoma patients.
Association of single nucleotide polymorphisms of ?2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma.
Astragaloside IV increases MMP-2 mRNA and protein expression in human lung cancer A549 cells.
Astragaloside IV inhibits cell invasion and metastasis in vulvar squamous cell carcinoma through the TGF-?1/FAK/AKT signaling pathway.
Astrocytes directly influence tumor cell invasion and metastasis in vivo.
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma.
Baicalin Suppresses Migration, Invasion and Metastasis of Breast Cancer via p38MAPK Signaling Pathway.
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Bcl-2 promotes invasion and lung metastasis by inducing matrix metalloproteinase-2.
Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-?/VEGF/Rho-GTPases: pivotal role of STAT-3.
Betulinic acid induces apoptosis and suppresses metastasis in hepatocellular carcinoma cell lines in vitro and in vivo.
Binding affinities for sulfonamide inhibitors with matrix metalloproteinase-2 using a linear response method.
Biochemical mechanisms of tumor invasion and metastases.
Biochemical mechanisms of tumor invasion and metastasis.
Biological evaluation of optically pure chiral binuclear copper(ii) complexes based on a rosin derivative as highly potential anticancer agents.
Biphenyl substituted lysine derivatives as recognition elements for the matrix metalloproteinases MMP-2 and MMP-9.
Blockade of Asparagine Endopeptidase Inhibits Cancer Metastasis.
Blockade of vascular angiogenesis by Aspergillus usamii var. shirousamii-transformed Angelicae Gigantis Radix and Zizyphus jujuba.
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK.
Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation.
Bornyl cis-4-Hydroxycinnamate Suppresses Cell Metastasis of Melanoma through FAK/PI3K/Akt/mTOR and MAPK Signaling Pathways and Inhibition of the Epithelial-to-Mesenchymal Transition.
BRD4 promotes metastatic potential in oral squamous cell carcinoma through the epigenetic regulation of the MMP2 gene.
Breast Cancer Recurrence Risk Assessment: Is Non-Invasive Monitoring an Option?
Brucine suppresses breast cancer metastasis via inhibiting epithelial mesenchymal transition and matrix metalloproteinases expressions.
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway.
C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9.
Caffeic Acid phenethyl ester inhibits oral cancer cell metastasis by regulating matrix metalloproteinase-2 and the mitogen-activated protein kinase pathway.
Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity.
Cambodian Phellinus linteus inhibits experimental metastasis of melanoma cells in mice via regulation of urokinase type plasminogen activator.
Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.
Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways.
Catalyser-21(TM), a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis.
Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity.
CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas.
Cell membrane-associated MT1-MMP dependent activation of MMP-2 in SiHa (human cervical cancer) cells.
Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics.
Changes to N-linked oligosaccharide chains of human serum immunoglobulin G and matrix metalloproteinase-2 with cancer progression.
Characterization of protease expression in human prostate-cancer cell-lines.
Chemical composition and pharmacological bio-efficacy of Parrotiopsis jacquemontiana (Decne) Rehder for anticancer activity.
Chemoinhibitory effect of mulberry anthocyanins on melanoma metastasis involved in the Ras/PI3K pathway.
Chitooligosaccharides inhibit activation and expression of matrix metalloproteinase-2 in human dermal fibroblasts.
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression.
CK2 inhibitor CX4945 induces sequential inactivation of proteins in the signaling pathways related with cell migration and suppresses metastasis of A549 human lung cancer cells.
Clinical Relevance of Increased Endothelial and Mesothelial Expression of Proangiogenic Proteases and VEGFA in the Omentum of Patients with Metastatic Ovarian High-Grade Serous Carcinoma.
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
Clinical role of MMP-2/TIMP-2 imbalance in hepatocellular carcinoma.
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Clinical significance of plasma MMP-2 and MMP-9 levels as biomarkers for tumor expression in breast cancer patients in Egypt.
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Clinicopathological and biological significance of human voltage-gated proton channel Hv1 over-expression in breast cancer.
Clinicopathological characteristics of carcinoma from unknown primary in cervical lymph nodes.
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-?B-Dependent Mechanism.
CNTF up-regulation of TIMP-2 in neuroblastoma cells.
Co-delivery of autophagy inhibitor and gemcitabine using a pH-activatable core-shell nanobomb inhibits pancreatic cancer progression and metastasis.
Coexpression of integrin alpha(v)beta3 and matrix metalloproteinase-2 (MMP-2) coincides with MMP-2 activation: correlation with melanoma progression.
Coexpression of vimentin and keratins by human melanoma tumor cells: correlation with invasive and metastatic potential.
Collagen induced MMP-2 activation in human breast cancer.
Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts.
Combination of ACY-241 and JQ1 Synergistically Suppresses Metastasis of HNSCC via Regulation of MMP-2 and MMP-9.
Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines.
Combination of nadroparin with radiotherapy results in powerful synergistic antitumor effects in lung adenocarcinoma A549 cells.
Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma.
Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas.
Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks.
Comparison of the prognostic value of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model.
Contribution of Matrix Metalloproteinase-2 Promoter Genotypes to Nasopharyngeal Cancer Susceptibility and Metastasis in Taiwan.
Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma.
Correlation between bone scan findings and collagenase activities in patients with breast cancer.
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinoma.
Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis.
Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas.
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice.
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Corrigendum to "Caffeic Acid Phenethyl Ester Inhibits Oral Cancer Cell Metastasis by Regulating Matrix Metalloproteinase-2 and the Mitogen-Activated Protein Kinase Pathway".
Corrigendum to "Eupatilin inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling" [Bioorg. Med. Chem. Lett. 28(19) (2018) 3150-3154].
Critical role for matrix metalloproteinase-9 in platelet-activating factor-induced experimental tumor metastasis.
CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells.
Curcumin effect on MMPs and TIMPs genes in a breast cancer cell line.
Curcumin loaded selenium nanoparticles synergize the anticancer potential of doxorubicin contained in self-assembled, cell receptor targeted nanoparticles.
Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2.
Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
Cutting to the Chase: How Matrix Metalloproteinase-2 Activity Controls Breast-Cancer-to-Bone Metastasis.
CXCL10 accelerates EMT and metastasis by MMP-2 in hepatocellular carcinoma.
Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells.
Cyclooxygenase-2 functions as a downstream mediator of lysophosphatidic acid to promote aggressive behavior in ovarian carcinoma cells.
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer.
Cyclophosphamide promotes pulmonary metastasis on mouse lung adenocarcinoma.
Cytokines, inducers and inhibitors modulate MMP-2 and MMP?9 secretion by human Fanconi anemia immortalized fibroblasts.
Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis.
Decreased expression of SERPINB1 correlates with tumor invasion and poor prognosis in hepatocellular carcinoma.
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Density-dependent regulation of cell-surface association of matrix metalloproteinase-2 (MMP-2) in breast-carcinoma cells.
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Des-?-carboxyl prothrombin induces matrix metalloproteinase activity in hepatocellular carcinoma cells by involving the ERK1/2 MAPK signalling pathway.
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Design, synthesis and biological evaluation of a new thieno[2,3-d]pyrimidine-based urea derivative with potential antitumor activity against tamoxifen sensitive and resistant breast cancer cell lines.
Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.
Detection of endometrial cancer by determination of matrix metalloproteinases in the uterine cavity.
Detection of type IV collagenase activity in malignant ascites.
Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters.
Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade.
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Different levels of TGFbeta, IL-10, IFNgamma and gelatinase A occur in experimental white and black metastases induced by bryostatin 1 or by phorbol ester-treated BL6T murine melanoma cells.
Different Proteins Regulated Apoptosis, Proliferation and Metastasis of Lung Adenocarcinoma After Radiotherapy at Different Time.
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Differential inductions of matrix metalloproteinase-2 and -9 in host tissues during the growth of ascitic sarcoma 180 cells in mice.
Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients.
Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP.
Distinct endobronchial expression of matrix-metalloproteinases (MMP) and their endogenous inhibitors in lung cancer.
Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases.
Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions.
Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis.
Down-regulation of osteopontin inhibits metastasis of hepatocellular carcinoma cells via a mechanism involving MMP-2 and uPA.
Downregulation of BRCA1 in A375 melanoma cell line increases radio-sensitivity and modifies metastatic and angiogenic gene expression.
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness.
Doxorubicin and Trifolium pratense L. (Red clover) extract synergistically inhibits brain and lung metastases in 4T1 tumor-bearing BALB/c mice.
DRP1 upregulation promotes pancreatic cancer growth and metastasis through increased aerobic glycolysis.
EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-?B signaling pathway.
Effect of Agmatine Sulfate on Modulation of Matrix Metalloproteinases
Effect of all trans-retinoic acid on the secretion of IV collagenase.
Effect of Fraxiparine, a type of low molecular weight heparin, on the invasion and metastasis of lung adenocarcinoma A549 cells.
Effect of isofebrifugine on the proliferation and invasion of human gastric cancer cells via MMP.
Effect of matrix metalloproteinase inhibitors on tumor growth and spontaneous metastasis.
Effect of metallothioneins on transformation of gelatinase A from human fibroblast WI-38 cells.
Effect of microRNA-206 on cytoskeleton remodelling by downregulating Cdc42 in MDA-MB-231 cells.
Effect of Sirtuin 1 inhibition on matrix metalloproteinase 2 and Forkhead box O3a expression in breast cancer cells.
Effect of troglitazone on tumor growth and pulmonary metastasis development of the mouse osteosarcoma cell line LM8.
Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression.
Effects of cigarette smoke condensate on oral squamous cell carcinoma cells.
Effects of hepatocyte growth factor/scatter factor on the invasion of colorectal cancer cells in vitro.
Effects of Lidocaine and Src Inhibition on Metastasis in a Murine Model of Breast Cancer Surgery.
Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the invasive capacity of these cell lines in vitro.
Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes.
Effects of zoledronic acid on proteinase plasma levels in patients with bone metastases.
EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest.
Elevated plasma levels of matrix metalloproteinase-9 (92-kd type IV collagenase/gelatinase B) in hepatocellular carcinoma.
Endometrial tumor invasiveness is related to metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expressions.
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence.
Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors.
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells.
Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Epigenetic regulation of multidrug-resistance and metastasis-related genes in human lung adenocarcinoma cells growing in ectopic or orthotopic organs of nude-mice.
Esophageal Cancer Development: Crucial Clues Arising from the Extracellular Matrix.
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
ETS-1 regulates vascular endothelial growth factor-induced matrix metalloproteinase-9 and matrix metalloproteinase-13 expression in human ovarian carcinoma cell SKOV-3.
Eupatilin inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling.
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Evaluation of Suppressive Effects of Tranilast on the Invasion/Metastasis Mechanism in a Murine Pancreatic Cancer Cell Line.
Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression.
Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer.
Evidence of the involvement of phosphatidylinositol 3-kinase in the migration, actin stress fiber formation, and alpha v beta 3-integrin-mediated adherence of human melanoma cells.
Exosome EpCAM promotes the metastasis of glioma by targeting the CD44 signaling molecule on the surface of glioma cells.
Exploring QSAR and pharmacophore mapping of structurally diverse selective matrix metalloproteinase-2 inhibitors.
Exploring the action of RGDV-gemcitabine on tumor metastasis, tumor growth and possible action pathway.
Exploring the Mechanism of Flaccidoxide-13-Acetate in Suppressing Cell Metastasis of Hepatocellular Carcinoma.
Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma.
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Expression and activity of MMPS and their regulators in ovarian cancer.
Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo.
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas.
Expression and serum levels of MMP-2 and MMP-9 during human melanoma progression.
Expression and significance of MMP2 and HIF-1? in hepatocellular carcinoma.
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas.
Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma.
Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors.
Expression of Alpha-Enolase (ENO1), Myc Promoter-Binding Protein-1 (MBP-1) and Matrix Metalloproteinases (MMP-2 and MMP-9) Reflect the Nature and Aggressiveness of Breast Tumors.
Expression of bcl-2 correlates with poor prognosis and modulates migration of nasopharyngeal carcinoma cells.
Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck.
Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance.
Expression of collagenase IV (basement membrane collagenase) activity in murine tumor cell hybrids that differ in metastatic potential.
Expression of CXCR4 and MMP-2 is associated with poor prognosis in patients with osteosarcoma.
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Expression of Discoidin Domain Receptor 2 (DDR2) Extracellular Domain in Pichia Pastoris and Functional Analysis in Synovial Fibroblasts and NIT3T3 Cells.
Expression of EMMPRIN in adenoid cystic carcinoma of salivary glands: correlation with tumor progression and patients' prognosis.
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa.
Expression of gelatinases A and B, stromelysin-3 and matrilysin genes in breast carcinomas: clinico-pathological correlations.
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.
Expression of laminin, collagen IV, fibronectin, and type IV collagenase in gastric carcinoma. An immunohistochemical study of 87 patients.
Expression of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of MMP (TIMP)-1 in conjunctival melanomas and clinical implications.
Expression of matrix metalloproteinase 2 (MMP-2), E-cadherin and Ki-67 in metastatic and non-metastatic canine mammary carcinomas.
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential.
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Expression of matrix metalloproteinase-2 and prostate-specific antigen in localized and metastatic prostate cancer.
Expression of matrix metalloproteinase-2 in renal cell carcinoma.
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Expression of matrix metalloproteinases 1 and 2 genes in a possible association with metastatic abilities of human pancreatic cancer cells.
Expression of Matrix Metalloproteinases and Its Inhibitor in Gastric Adenocarcinoma.
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma.
Expression of MMP-2 and TIMP-3 with incidence and prognosis of giant-cell tumor of the bone.
Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma.
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Expression of MMP-2, MMP-9, and urokinase-type plasminogen activator in cervical intraepithelial neoplasia.
Expression of MMP2, MMP9 and MMP3 in breast cancer brain metastasis in a rat model.
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.
Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells.
Expression of SHP2 and Related Markers in Non-Small Cell Lung Cancer: A Tissue Microarray Study of 80 Cases.
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology.
Expression of type IV collagen and matrix metalloproteinase-2 (type IV collagenase) in relation to nodal status in laryngeal cancer.
Expression of type IV collagenase and procollagen genes and its correlation with the tumorigenic, invasive, and metastatic abilities of oncogene-transformed human bronchial epithelial cells.
Expression of vascular endothelial growth factor and matrix metalloproteinase-2 correlates with the invasion and metastasis of hepatocellular carcinoma.
Expression of WTH3 in breast cancer tissue and the effects on the biological behavior of breast cancer cells.
Expression of Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis.
Expression patterns of seprase, a membrane serine protease, in cervical carcinoma and cervical intraepithelial neoplasm.
Expression, purification, refolding and in vitro recovery of active full length recombinant human gelatinase MMP-9 in Escherichia coli.
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
Ezrin-Radixin-Moesin Binding Phosphoprotein 50 (EBP50) Suppresses the Metastasis of Breast Cancer and HeLa Cells by Inhibiting Matrix Metalloproteinase-2 Activity.
FAK is involved in invasion and metastasis of hepatocellular carcinoma.
Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells.
First evidence that the anti-malarial drug Artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases.
Flubendazole elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Folate-decorated arginine-based poly(ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells.
Folate-targeted paclitaxel-conjugated polymeric micelles inhibits pulmonary metastatic hepatoma in experimental murine H22 metastasis models.
Full-length L1CAM and not its ?2?27 splice variant promotes metastasis through induction of gelatinase expression.
Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB.
Functional examination of novel kisspeptin phosphinic peptides.
Functional expression of CXC chemokine recepter-4 mediates the secretion of matrix metalloproteinases from mouse hepatocarcinoma cell lines with different lymphatic metastasis ability.
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer.
Fusion expression of DDR2 extracellular domain in insect cells and its purification and function characterization.
Galloyl cyclic-imide derivative CH1104I inhibits tumor invasion through suppressing matrix metalloproteinase activity.
Gamabufotalin suppressed osteosarcoma stem cells through the TGF-?/periostin/PI3K/AKT pathway.
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Gaseous nitrogen oxide promotes human lung cancer cell line A549 migration, invasion, and metastasis via iNOS-mediated MMP-2 production.
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Gelatinase and inhibitor expression in soft tissue sarcomas: lack of correlation with distant metastasis.
Gelatinase levels in male and female breast cancer.
Gelatinases A and B expression in human colorectal cancer in upper Egypt: a clinicopathological study.
Gelatinases and their inhibitors in tumor metastasis: from biological research to medical applications.
Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography.
Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1{alpha}, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma.
Generation and antitumor effects of an engineered and energized fusion protein VL-LDP-AE composed of single-domain antibody and lidamycin.
Genes controlling spread of breast cancer to lung "gang of 4".
Genetic Predisposition of Polymorphisms in HMGB1-Related Genes to Breast Cancer Prognosis in Korean Women.
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.
Genistein reinforces the inhibitory effect of Cisplatin on liver cancer recurrence and metastasis after curative hepatectomy.
Genistein treatment duration effects biomarkers of cell motility in human prostate.
Genistein-selenium combination induces growth arrest in prostate cancer cells.
GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies.
GOLPH3 Overexpression is Closely Correlated with Poor Prognosis in Human Non-Small Cell Lung Cancer and Mediates its Metastasis Through Upregulating MMP-2 and MMP-9.
Granulocyte colony-stimulating factor (G-CSF)-mediated signaling regulates type IV collagenase activity in head and neck cancer cells.
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
HAND2-AS1 inhibits invasion and metastasis of cervical cancer cells via microRNA-330-5p-mediated LDOC1.
HIF-1? contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
HIF-2? as a prognostic marker for breast cancer progression and patient survival.
High Expression of GRP78 Promotes Invasion and Metastases in Patients with Esophageal Squamous Cell Carcinoma.
High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases.
High Mobility Group Box Protein 1 Serves as a Potential Prognostic Marker of Lung Cancer and Promotes Its Invasion and Metastasis by Matrix Metalloproteinase-2 in a Nuclear Factor-?B-Dependent Manner.
High threshold of ?1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2).
High VEGF-D and Low MMP-2 Serum Levels Predict Nodal-Positive Disease in Invasive Bladder Cancer.
High-throughput functional profiling of single adherent cells via hydrogel drop-screen.
Highly activated matrix metalloproteinase-2 secreted from clones of metastatic lung nodules of nude mice injected with human fibrosarcoma HT1080.
Hispolon suppresses SK-Hep1 human hepatoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen activator through the PI3K/Akt and ERK signaling pathways.
Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer.
HMGA2 gene silencing reduces epithelial-mesenchymal transition and lymph node metastasis in cervical cancer through inhibiting the ATR/Chk1 signaling pathway.
Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer.
Human papillomavirus E6-regulated microRNA-20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2.
Hypoxia level and matrix metalloproteinases-2 and -9 activity in Lewis lung carcinoma: correlation with metastasis.
Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2.
Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells.
Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer.
Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.
Identification of Non-Zinc Binding Inhibitors of MMP-2 Through Virtual Screening and Subsequent Rescoring.
Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation.
Identification of substrate sequences for membrane type-1 matrix metalloproteinase using bacteriophage peptide display library.
IL-10 inhibition of human prostate PC-3 ML cell metastases in SCID mice: IL-10 stimulation of TIMP-1 and inhibition of MMP-2/MMP-9 expression.
IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in ovarian cancer cells.
Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways.
Immunoassays of the metalloproteinase (MMP-2) and tissue inhibitor of metalloproteinase (TIMP 1 and 2) levels in noninvasive and metastatic PC-3 clones: effects of taxol.
Immunocytochemical detection of matrix metalloproteinase expression in prostate cancer.
Immunocytochemical detection of the expression of members of the matrix metalloproteinase family in adenocarcinomas of the pancreas.
Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours.
Immunoexpression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in the metastasis of squamous cell carcinoma of the human tongue.
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage I and II endometrial cancer.
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage IB cervical cancer.
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Immunohistochemical distribution of type IV collagenase in normal, dysplastic and neoplastic canine mammary gland.
Immunohistochemical evaluation of MMP-2, MMP-9 and CD31/microvascular density in squamous cell carcinomas of the floor of the mouth.
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Immunohistochemical levels of matrix metalloproteinase-2 and CD44 variant 6 protein in the diagnosis and lateral cervical lymph node metastasis of papillary thyroid carcinoma.
Immunohistochemical predictors in squamous cell carcinoma of the tongue and floor of the mouth.
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma.
In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis.
In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
In vitro and in vivo antimetastatic effects of Terminalia catappa L. leaves on lung cancer cells.
In vitro and in vivo matrix metalloproteinase production by pancreatic cancer cells and by distant organs.
In vitro antioxidative potential of lactoferrin and black tea polyphenols and protective effects in vivo on carcinogen activation, DNA damage, proliferation, invasion, and angiogenesis during experimental oral carcinogenesis.
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
Increased E1AF expression in mouse fibrosarcoma promotes metastasis through induction of MT1-MMP expression.
Increased expression and activation of gelatinolytic matrix metalloproteinases is associated with the progression and recurrence of human cervical cancer.
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas.
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Increased serum type IV collagen 7-S levels in patients with hepatic metastasis.
Induction of an invasive phenotype in benign tumor cells with a laminin A-chain synthetic peptide.
Induction of RECK by nonsteroidal anti-inflammatory drugs in lung cancer cells.
Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.
Influence of cytokines and growth factors on matrix metalloproteinase-2 production and invasion of human renal cancer.
Influence of oleic acid on the expression, activation and activity of gelatinase A produced by oncogene-transformed human bronchial epithelial cells.
Influence of persistent canine distemper virus infection on expression of RECK, matrix-metalloproteinases and their inhibitors in a canine macrophage/monocytic tumour cell line (DH82).
Influence of the host microenvironment on the clonal selection of human colon carcinoma cells during primary tumor growth and metastasis.
Inhibiting tissue invasion and metastasis as targets for cancer therapy.
Inhibition of AIDS-Kaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: implications for an anti-angiogenic therapy.
Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells.
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins.
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor.
Inhibition of invasion and metastasis of MHCC97H cells by expression of snake venom cystatin through reduction of proteinases activity and epithelial-mesenchymal transition.
Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine.
Inhibition of matrix metalloproteinase-14 in osteosarcoma cells by clodronate.
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone.
Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid.
Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma.
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma.
Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment.
Inhibition of Tumor Growth and Metastasis by Non-Small Cell Lung Cancer Cells Transfected with Cyclin D1-Targeted siRNA.
Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells.
Inhibitory effect of a gamma-oryzanol-rich fraction from purple rice extract on lipopolysaccharide-induced metastasis in human colon cancer cells.
Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.
Inhibitory effect of chitooligosaccharides on matrix metalloproteinase-9 in human fibrosarcoma cells (HT1080).
Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo.
Inhibitory effect of green tea polyphenols on membrane-type 1 matrix metalloproteinase, MT1-MMP.
Inhibitory effect of penta-acetyl geniposide on C6 glioma cells metastasis by inhibiting matrix metalloproteinase-2 expression involved in both the PI3K and ERK signaling pathways.
Inhibitory effect of the carnosine-gallic acid synthetic peptide on MMP-2 and MMP-9 in human fibrosarcoma HT1080 cells.
Inhibitory effects of Chanling Gao on the proliferation and liver metastasis of transplanted colorectal cancer in nude mice.
Inhibitory effects of oleic and docosahexaenoic acids on lung metastasis by colon-carcinoma-26 cells are associated with reduced matrix metalloproteinase-2 and -9 activities.
Inhibitory effects of tetrandrine on epidermal growth factor-induced invasion and migration in HT29 human colorectal adenocarcinoma cells.
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells.
Integrin ?v?6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2.
Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
Interpreting gelatinase activity in tumor tissue and serum as a prognostic marker of naturally developing canine tumors.
Interstitial collagenases as markers of tumor progression.
Intrabronchial orthotopic propagation of human lung adenocarcinoma--characterizations of tumorigenicity, invasion and metastasis.
Intracellular expression of a single-chain antibody directed against type IV collagenase inhibits the growth of lung cancer xenografts in nude mice.
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Intratumoral macrophage counts correlate with tumor progression in colorectal cancer.
Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential.
Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung.
Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis.
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Involvement of MMP-2 in adriamycin resistance dependent on ERK1/2 signal pathway in human osteosarcoma MG-63 cells.
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.
Involvement of STAT5 in Oncogenesis.
Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts.
Is dual inhibition of metalloenzymes HDAC-8 and MMP-2 a potential pharmacological target to combat hematological malignancies?
JWA suppresses tumor angiogenesis via Sp1-activated MMP-2 and its prognostic significance in human gastric cancer.
Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells.
Ketoprofen in topical formulation decreases the matrix metalloproteinase-2 expression and pulmonary metastatic incidence in nude mice with osteosarcoma.
Knockdown of Angiopoietin-2 Suppresses Metastasis in Human Pancreatic Carcinoma by Reduced Matrix Metalloproteinase-2.
Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma.
Knockdown of Li-cadherin increases metastatic behaviors of LoVo cells.
Korean Byungkyul - Citrus platymamma Hort.et Tanaka flavonoids induces cell cycle arrest and apoptosis, regulating MMP protein expression in Hep3B hepatocellular carcinoma cells.
Lentiviral-mediated Smad4 RNAi promotes SMMC-7721 cell migration by regulation of MMP-2, VEGF and MAPK signaling.
Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers.
Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer.
Levels of Circulating TIMP-2 and MMP2-TIMP2 Complex Are Decreased in Squamous Cervical Carcinoma.
Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells.
Liver metastasis formation by laminin-1 peptide (LQVQLSIR)-adhesion selected B16-F10 melanoma cells.
LncRNA GAS5 is a critical regulator of metastasis phenotype of melanoma cells and inhibits tumor growth in vivo.
Long non-coding RNA SNHG15 indicates poor prognosis of non-small cell lung cancer and promotes cell proliferation and invasion.
Long Noncoding RNA Highly Up-regulated in Liver Cancer Predicts Unfavorable Outcome and Regulates Metastasis by MMPs in Triple-negative Breast Cancer.
Low expression of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) indicates a shorter survival after resection in patients with adenocarcinoma of the lung.
Luteolin inhibits the proliferation, adhesion, migration and invasion of choroidal melanoma cells in vitro.
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
MAG-2 promotes invasion, mobility and adherence capability of lung cancer cells by MMP-2, CD44 and intracellular calcium in vitro.
Magnetic Semiconductor Gd-Doping CuS Nanoparticles as Activatable Nanoprobes for Bimodal Imaging and Targeted Photothermal Therapy of Gastric Tumors.
MAGP2, a Component of Extracellular Matrix, Is Upregulated in Colorectal Cancer and Negatively Modulated by miR-200b-3p.
Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential.
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis.
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2.
Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis.
Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.
Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value.
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast.
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma?
Matrix metalloproteinase-2 and -7 expression in colorectal cancer.
Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system.
Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer.
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Matrix metalloproteinase-2 as a target for head and neck cancer therapy.
Matrix metalloproteinase-2 contributes to cancer cell migration on collagen.
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review.
Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura.
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Matrix metalloproteinases and metastatic cancer.
Matrix metalloproteinases and their inhibitors in correlation to proliferative and classical tumour markers during surgical therapy of colorectal liver metastases.
Matrix metalloproteinases as diagnostic (MMP-13) and prognostic (MMP-2, MMP-9) markers of prostate cancer.
Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression.
Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation.
Matrix metalloproteinases in Vietnamese patients with colorectal cancer.
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
MCU-dependent mitochondrial Ca(2+) inhibits NAD(+)/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells.
Mechanism of metastasis inhibition by cartilage polysaccharide in breast cancer cells.
MED28 and forkhead box M1 (FOXM1) mediate matrix metalloproteinase 2 (MMP2)-dependent cellular migration in human nonsmall cell lung cancer (NSCLC) cells.
MEK4 function, genistein treatment, and invasion of human prostate cancer cells.
Melanoma differentiation-associated gene-7 suppresses human gastric cancer cell invasion and migration.
Melatonin inhibits lung metastasis of gastric cancer in vivo.
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion.
Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis.
Messenger RNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human hepatocellular carcinoma.
Metallopeptidase, neurolysin, as a novel molecular tool for analysis of properties of cancer-producing matrix metalloproteinases-2 and -9.
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Metastasis of human colon tumor cells in vivo: correlation with the overexpression of plasminogen activators and 72 kDa gelatinase.
Metastatic Inhibitory and Radical Scavenging Efficacies of Saponins Extracted from the Brittle Star (Ophiocoma erinaceus).
Metformin Inhibited Growth, Invasion and Metastasis of Esophageal Squamous Cell Carcinoma in Vitro and in Vivo.
Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo.
Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2/-9 expression mediated by NF-?B activation.
Microenvironment-induced TIMP2 loss by cancer-secreted exosomal miR-4443 promotes liver metastasis of breast cancer.
MicroRNA-20b inhibits trophoblast cell migration and invasion by targeting MMP-2.
MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4.
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression.
MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-?B signaling.
miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.
miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression.
miR-302b suppresses cell invasion and metastasis by directly targeting AKT2 in human hepatocellular carcinoma cells.
miR-338-3p inhibits cell growth, invasion, and EMT process in neuroblastoma through targeting MMP-2.
MiR-95-5p involves in the migration and invasion of trophoblast cells by targeting low density lipoprotein receptor-related protein 6.
miRNA-218 inhibits osteosarcoma cell migration and invasion by down-regulating of TIAM1, MMP2 and MMP9.
MMI-166, a selective matrix metalloproteinase inhibitor, promotes apoptosis in human pancreatic cancer.
MMP-1 and MMP-2 expression in uterine leiomyosarcoma and correlation with different clinicopathologic parameters.
MMP-2 and MMP-9 gene polymorphisms associated with cervical cancer risk.
MMP-2 and MMP-9 in lymph-node-positive bladder cancer.
MMP-2 and TIMP-2 in Cutaneous Melanoma: Association With Prognostic Factors and Description in Cutaneous Metastases.
MMP-2 but not MMP-9 associated with COX-2 and survival in gastric cancer.
MMP-2 functions as an early response protein in ovarian cancer metastasis.
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
MMP-2 positivity and age less than 40 years increases the risk for recurrence in premenopausal patients with node-positive breast carcinoma.
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
MMP-2, TIMP-2 and CD44v6 Expression in Non-small-cell Lung Carcinomas.
MMP-9 directed shRNAs as relevant inhibitors of matrix metalloproteinase 9 activity and signaling.
MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis.
MMP-9-hemopexin domain hampers adhesion and migration of colorectal cancer cells.
MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2.
Modulation of membrane type 1 matrix metalloproteinase by LPS and gamma interferon bound to extracellular matrix in intestinal crypt cells.
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin A chain.
Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis.
Molecular docking and inhibition of matrix metalloproteinase-2 by novel difluorinatedbenzylidene curcumin analog.
Molecular dynamics simulations of metalloproteinases types 2 and 3 reveal differences in the dynamic behavior of the S1' binding pocket.
Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling.
Multidrug-resistant tumor cells with decreased malignancy: a role for integrin alphavbeta3.
Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma.
Multiple molecular modelling studies on some derivatives and analogues of glutamic acid as matrix metalloproteinase-2 inhibitors.
Multistage-responsive nanovehicle to improve tumor penetration for dual-modality imaging-guided photodynamic-immunotherapy.
N-?-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas.
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
Naringin suppresses cell metastasis and the expression of matrix metalloproteinases (MMP-2 and MMP-9) via the inhibition of ERK-P38-JNK signaling pathway in human glioblastoma.
Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells.
NEK2 serves as a prognostic biomarker for hepatocellular carcinoma.
Neural cell adhesion molecule potentiates invasion and metastasis of melanoma cells through CAMP-dependent protein kinase and phosphatidylinositol 3-kinase pathways.
New clinical scoring system for prognosis of early recurrence of colorectal liver metastases after surgical treatment.
New NSAID-Pt(IV) prodrugs to suppress metastasis and invasion of tumor cells and enhance anti-tumor effect in vitro and in vivo.
NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice.
NIK- and IKK?-binding protein promotes colon cancer metastasis by activating the classical NF-?B pathway and MMPs.
Non-steroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 expression via repression of transcription in lung cancer cells.
Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line.
NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo.
O-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood-Brain Barrier.
Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells.
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Organ heterogeneity of host-derived matrix metalloproteinase expression and its involvement in multiple-organ metastasis by lung cancer cell lines.
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis.
Osteopontin promotes hepatocellular carcinoma invasion by up-regulating MMP-2 and uPA expression.
Osteoprotegerin expression in triple-negative breast cancer cells promotes metastasis.
Overexpression of eIF4E in colorectal cancer patients is associated with liver metastasis.
Overexpression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in liver from patients with gastrointestinal adenocarcinoma and no detectable metastasis.
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Overexpression of myeloid zinc finger 1 suppresses matrix metalloproteinase-2 expression and reduces invasiveness of SiHa human cervical cancer cells.
Overexpression of protein kinase C-alpha and -beta isozymes by stromal dendritic cells in basal and squamous cell carcinoma.
Overexpression of Rab40b Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis via PI3K/AKT Signaling Pathway.
Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition.
Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src.
Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS.
Oxytocin inhibits ovarian cancer metastasis by repressing the expression of MMP-2 and VEGF.
p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription.
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2.
p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR.
Pancreatic Stellate Cells Activation and Matrix Metallopeptidase 2 Expression Correlate With Lymph Node Metastasis in Pancreatic Carcinoma.
Papers to appear in forthcoming issues
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Peroxisome proliferator-activated receptor-? inhibits pancreatic cancer cell invasion and metastasis via regulating MMP-2 expression through PTEN.
Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester.
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Pinostilbene Hydrate Suppresses Human Oral Cancer Cell Metastasis by Downregulation of Matrix Metalloproteinase-2 Through the Mitogen-Activated Protein Kinase Signaling Pathway.
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-?B-dependent transcription.
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Plasma gelatinase levels in patients with primary breast cancer in relation to axillary lymph node status, Her2/neu expression and other clinicopathological variables.
Plasma matrix metalloproteinase 2 levels and breast cancer risk.
Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases.
Platelet-activating factor mediates MMP-2 expression and activation via phosphorylation of cAMP-response element-binding protein and contributes to melanoma metastasis.
Positive and negative transcriptional elements of the human type IV collagenase gene.
Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail.
Potent anti-cancer effects of citrus peel flavonoids in human prostate xenograft tumors.
Potent tumor targeting drug release system comprising MMP-2 specific peptide fragment with self-assembling characteristics.
Pre-clinical investigation of STAT3 pathway in bladder cancer: Paving the way for clinical translation.
Predicting Novel Antitumor Agents: 3D-Pharmacophore Mapping of ?-N-biaryl Ether Sulfonamide-Based Hydroxamates as Potentially MMP-2 Inhibitors.
Prediction of metastasis in oral squamous cell carcinoma through phenotypic evaluation and gene expression of E-cadherin, ?-catenin, matrix metalloproteinase-2, and matrix metalloproteinase-9 biomarkers with clinical correlation.
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.
Preliminary evaluation of inhibition of matrix-metalloprotease MMP-2 and MMP-9 by Passiflora edulis and P foetida aqueous extracts.
Preoperative Serum Levels of Matrix Metalloproteinase-2 (MMP-2) and Survival of Breast Cancer among Korean Women.
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice.
Production and characterization of a human single-chain Fv to collagenase IV.
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Production of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human breast carcinomas.
Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients.
Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection.
Prognostic Significance of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase 2 in Epithelial Ovarian Cancer.
Prognostic significance of matrix metalloproteinases 2 and 9 in bladder cancer.
Prognostic significance of matrix metalloproteinases-2 activation ratio in renal cell carcinoma.
Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in human cutaneous melanoma.
Prognostic value of matrix metalloproteinase-2 (MMP-2) expression in endometrial endometrioid adenocarcinoma.
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma.
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Promoter hypermethylation and silencing of tissue factor pathway inhibitor-2 in oral squamous cell carcinoma.
Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas.
Proteolipid protein 2 is associated with melanoma metastasis.
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Proteolytic imbalance is reversed after therapeutic surgery in breast cancer patients.
Proteome analysis identified the PPAR? ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.
Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-?B pathway and MMP-2 production by targeting RhoB activation.
Psychological Stress Up-Regulates CD147 Expression Through Beta-Arrestin1/ERK to Promote Proliferation and Invasiveness of Glioma Cells.
PTEN and TRAIL genes loaded zein nanoparticles as potential therapy for hepatocellular carcinoma.
Purification and characterization of catalytic domains of gelatinase A with or without fibronectin insert for high-throughput inhibitor screening.
Qingyihuaji Formula Inhibits Progress of Liver Metastases From Advanced Pancreatic Cancer Xenograft by Targeting to Decrease Expression of Cyr61 and VEGF.
Quantum dots based molecular beacons for in vitro and in vivo detection of MMP-2 on tumor.
Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
Raf kinase inhibitor protein suppresses nuclear factor-?B-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression.
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Ratiometric Imaging of MMP-2 Activity Facilitates Tumor Detection Using Activatable Near-Infrared Fluorescent Semiconducting Polymer Nanoparticles.
Realgar Nanoparticles Inhibit Migration, Invasion and Metastasis in a Mouse Model of Breast Cancer by Suppressing Matrix Metalloproteinases and Angiogenesis.
Recent opportunities in matrix metalloproteinase inhibitor drug design for cancer.
Recombinant human prothrombin kringle-2 inhibits B16F10 melanoma metastasis through inhibition of neovascularization and reduction of matrix metalloproteinase expression.
Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting ?5?1 integrin to downregulate Akt and MMP-2.
Red ginseng extract reduced metastasis of colon cancer cells in vitro and in vivo.
Redox state of adipose tissue for patients with gastric cancer and its connection with the body mass index and distance from the tumor.
Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer.
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway.
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).
Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance.
Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts.
Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.
Regulation of MT1-MMP and MMP-2 by the serpin PEDF: a promising new target for metastatic cancer.
Regulation of the Mr 72,000 type IV collagenase by the type I insulin-like growth factor receptor.
Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma.
Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells.
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Relationships between the level of matrix metalloproteinase-2 and tumor size of breast cancer.
Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells.
Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation.
Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells.
Resveratrol inhibits migration and invasion of human breast-cancer cells.
Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-?B Pathway.
Retroviral delivery of TIMP-2 inhibits H-ras-induced migration and invasion in MCF10A human breast epithelial cells.
RNAi targeting urokinase-type plasminogen activator receptor inhibits metastasis and progression of oral squamous cell carcinoma in vivo.
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Role of crocin in several cancer cell lines: An updated review.
Role of extracellular matrix in breast cancer development: a brief update.
Role of GPER on proliferation, migration and invasion in ligand-independent manner in human ovarian cancer cell line SKOV3.
Role of interleukin 10 and transforming growth factor beta1 in the angiogenesis and metastasis of human prostate primary tumor lines from orthotopic implants in severe combined immunodeficiency mice.
Role of interleukin-8 in tumor growth and metastasis of human melanoma.
Role of L1 cell adhesion molecule (L1CAM) in the metastatic cascade: promotion of dissemination, colonization, and metastatic growth.
Role of matrix metalloproteinase-9 in in vitro invasion of esophageal carcinoma cells.
Role of serum matrix metalloproteinase-2 and -9 to predict breast cancer progression.
Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.
Rubus idaeus extract suppresses migration and invasion of human oral cancer by inhibiting MMP-2 through modulation of the Erk1/2 signaling pathway.
RUNX3 Inhibits the Invasion and Metastasis of Human Colon Cancer HT-29 Cells by Upregulating MMP-2/9.
Ruscogenin suppressed the hepatocellular carcinoma metastasis via PI3K/Akt/mTOR signaling pathway.
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
S-Allylcysteine reduces breast tumor cell adhesion and invasion.
S100A4 antisense oligodeoxynucleotide suppresses invasive potential of neuroblastoma cells.
S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity.
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells.
Salinomycin suppresses TGF-?1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells.
SB225002 inhibits prostate cancer invasion and attenuates the expression of BSP, OPN and MMP?2.
Sea cucumber extract TBL-12 inhibits the proliferation, migration, and invasion of human prostate cancer cells through the p38 mitogen-activated protein kinase and intrinsic caspase apoptosis pathway.
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.
Secretome protein signature of human pancreatic cancer stem-like cells.
Secretory leukocyte protease inhibitor is associated with MMP-2 and MMP-9 to promote migration and invasion in SNU638 gastric cancer cells.
Selection of invasive and metastatic subpopulations from a heterogeneous human melanoma cell line.
Selective non-zinc binding MMP-2 inhibitors: Novel benzamide Ilomastat analogs with anti-tumor metastasis.
Selective water-soluble gelatinase inhibitor prodrugs.
Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways.
Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis.
Seprase, a membrane-type serine protease, has different expression patterns in intestinal- and diffuse-type gastric cancer.
SERPINA3 Silencing Inhibits the Migration, Invasion, and Liver Metastasis of Colon Cancer Cells.
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma.
Serum levels and tissue expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinases 2 (TIMP-2) in colorectal cancer patients.
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients.
Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension.
Serum matrix metalloproteinase-2 in patients with malignant melanoma.
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Serum MMP-2 as a potential predictive marker for papillary thyroid carcinoma.
Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways.
ShRNA knock-down of CXCR7 inhibits tumour invasion and metastasis in hepatocellular carcinoma after transcatheter arterial chemoembolization.
Significance of serum type IV collagenolytic activities and gelatinase levels for detection of metastasis in murine RCT sarcoma.
Silence of ?1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells.
Silencing cAMP-response element-binding protein (CREB) identifies CYR61 as a tumor suppressor gene in melanoma.
Silencing expression of the NANOG gene and changes in migration and metastasis of urinary bladder cancer cells.
Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell.
Silencing of TMSG1 enhances metastasis capacity by targeting V-ATPase in breast cancer.
Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression.
Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Silibinin inhibits triple negative breast cancer cell motility by suppressing TGF-?2 expression.
Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways.
Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma.
Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells.
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor.
Somatostatin Octapeptide Inhibits Cell Invasion and Metastasis in Hepatocellular Carcinoma Through PEBP1.
Soybean saponin inhibits tumor cell metastasis by modulating expressions of MMP-2, MMP-9 and TIMP- 2.
SPAG5 promotes osteosarcoma metastasis via activation of FOXM1/MMP2 axis.
SPARC is associated with gastric cancer progression and poor survival of patients.
Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells.
Spermidine inhibits MMP-2 via modulation of histone acetyltransferase and histone deacetylase in HDFs.
Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors.
Stage-specific expression analysis ofMMP-2 & MMP-9 in laryngeal carcinoma.
Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells.
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
Stat3 Is Involved in Angiotensin II-Induced Expression of MMP2 in Gastric Cancer Cells.
Status of research on matrix metalloproteinases (MMPs) in India.
Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors.
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases.
Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2.
Stromal-epithelial interaction in type IV collagenase expression and activation: The role in cancer metastasis.
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Study on antitumor activities of the chrysin-chromene-spirooxindole on Lewis lung carcinoma C57BL/6 mice in vivo.
Sulforaphene Interferes with Human Breast Cancer Cell Migration and Invasion through Inhibition of Hedgehog Signaling.
Superoxide- and NO-dependent mechanisms of antitumor and antimetastatic effect of L-arginine hydrochloride and coenzyme Q10.
Suppression of gelatinase production with decreased invasiveness of choriocarcinoma cells by human recombinant interferon beta.
Suppression of lung cancer cell invasion and metastasis by connexin43 involves the secretion of follistatin-like 1 mediated via histone acetylation.
Suppression on metastasis by rhubarb through modulation on MMP-2 and uPA in human A549 lung adenocarcinoma: An ex vivo approach.
Suppressive effects of microRNA-16 on the proliferation, invasion and metastasis of hepatocellular carcinoma cells.
Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions.
Surfactin from Bacillus subtilis attenuates ambient air particulate matter-promoted human oral cancer cells metastatic potential.
Synergistic anticancer effects of timosaponin AIII and ginsenosides in MG63 human osteosarcoma cells.
Synthesis and evaluation of myxochelin analogues as antimetastatic agents.
Synthesis, structure and characterization of novel Cd(II) and Zn(II) complexes with the condensation product of 2-formylpyridine and selenosemicarbazide Antiproliferative activity of the synthesized complexes and related selenosemicarbazone complexes.
Synthesized tetrahydroisoquinoline alkaloid exerts anticancer effects at least in part by suppressing NF??B?regulated proteins in A549 human lung cancer cells.
Targeting angiogenic pathway for chemoprevention of experimental colon cancer using C-phycocyanin as cyclooxygenase-2 inhibitor.
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.
Targeting of colorectal cancer growth, metastasis, and anti-apoptosis in BALB/c nude mice via APRIL siRNA.
Targeting STAT3 affects melanoma on multiple fronts.
Targeting the MMP-14/MMP-2/integrin ?v?3 axis with multispecific N-TIMP2-based antagonists for cancer therapy.
Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions.
Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells.
TGF-?1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-?B/IL-6/MMP-2.
TGF-?1 inhibits the growth and metastasis of tongue squamous carcinoma cells through Smad4.
TGF-beta1 promotes liver metastasis of pancreatic cancer by modulating the capacity of cellular invasion.
The a3 Isoform Vacuolar Type H+-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells.
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.
The angiosuppressive effects of 20(R)- ginsenoside Rg3.
The anti-alcohol dependency drug disulfiram inhibits the viability and progression of gastric cancer cells by regulating the Wnt and NF-?B pathways.
The Anti-tumoral Effect of ?-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGF?1 Gene Expression in Pre-surgical Breast Cancer Patients.
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
The C3G/Rap1 pathway promotes secretion of MMP-2 and MMP-9 and is involved in serous ovarian cancer metastasis.
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
The combination of sorafenib and radiation preferentially inhibits breast cancer stem cells by suppressing HIF-1? expression.
The correlation between immunohistochemical expression of MMP-2 and the prognosis of epithelial ovarian cancer.
The E2 protein of human papillomavirus type 8 increases the expression of matrix metalloproteinase-9 in human keratinocytes and organotypic skin cultures.
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
The effect of PI3K inhibitor LY294002 and gemcitabine hydrochloride combined with ionizing radiation on the formation of vasculogenic mimicry of Panc-1 cells in vitro and in vivo.
The enamel matrix derivative (Emdogain) enhances human tongue carcinoma cells gelatinase production, migration and metastasis formation.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma.
The expression of ATF3, MMP-2 and maspin in tissue chip of glioma.
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
The expression of MMP-2 and TIMP-2 in patients with primary colorectal adenocarcinoma: correlation with liver metastasis.
The extracellular matrix produced by bovine corneal endothelial cells contains progelatinase A.
The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump.
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
The impact of matrix metalloproteinase 2 on prognosis and clinicopathology of breast cancer patients: a systematic meta-analysis.
The In Ovo Chick Chorioallantoic Membrane (CAM) Assay as an Efficient Xenograft Model of Hepatocellular Carcinoma.
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
The influence of vascular endothelial growth factor-A and matrix metalloproteinase-2 and -9 in angiogenesis, metastasis, and prognosis of endometrial cancer.
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
The leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through STAT3-dependent up-regulation of matrix metalloproteinase 2.
The metallo-disintegrin ADAM10 (MADM) from bovine kidney has type IV collagenase activity in vitro.
The p75(NTR) metastasis suppressor inhibits urokinase plasminogen activator, matrix metalloproteinase-2 and matrix metalloproteinase-9 in PC-3 prostate cancer cells.
The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study.
The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
The role of gelatinase in hepatic metastasis of colorectal cancer.
The role of gelatinases in colorectal cancer progression and metastasis.
The role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the development of esophageal cancer.
The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma.
The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis.
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma.
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
The role of SDF-1/CXCR4 axis in ovarian cancer metastasis.
The role of the activated form of matrix metalloproteinase-2 in urothelial cancer.
The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer.
The Target Differences of Anti-Tumorigenesis Potential of Curcumin and its Analogues Against HER-2 Positive and Triple-Negative Breast Cancer Cells.
Therapeutic and analysis model of intrahepatic metastasis reflects clinical behavior of hepatocellular carcinoma.
Therapeutic effects of tyroserleutide on lung metastasis of human hepatocellular carcinoma SK-HEP-1 and its mechanism affecting ICAM-1 and MMP-2 and -9.
Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression.
Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells.
Thymoquinone inhibits metastasis of renal cell carcinoma cell 786-O-SI3 associating with downregulation of MMP-2 and u-PA and suppression of PI3K/Src signaling.
TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis.
TIMP-2 gene rs4789936 polymorphism is associated with increased risk of breast cancer and poor prognosis in Southern Chinese women.
TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis.
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer.
TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo.
Tomatidine inhibits cell invasion through the negative modulation of gelatinase and inactivation of p38 and ERK.
TPX2 silencing mediated by joint action of microvesicles and ultrasonic radiation inhibits the migration and invasion of SKOV3 cells.
Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line.
Transcriptional Repressor Snail and Metastasis in Hepatocellular Carcinoma.
Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma.
Transcutaneous carbon dioxide induces mitochondrial apoptosis and suppresses metastasis of oral squamous cell carcinoma in vivo.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Transforming growth factor beta1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro.
Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue.
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression.
Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
Tumor-elicited polymorphonuclear cells, in contrast to "normal" circulating polymorphonuclear cells, stimulate invasive and metastatic potentials of rat mammary adenocarcinoma cells.
Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1).
Tumour-associated fibrinolysis: the prognostic relevance of plasminogen activators uPA and tPA in human breast cancer.
Type I collagen-induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells.
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.
Type IV collagenase activity of a primary HSV-2-induced hamster fibrosarcoma and its in vivo metastases and in vitro clones.
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Unconjugated Bilirubin Is a Novel Prognostic Biomarker for Nasopharyngeal Carcinoma and Inhibits Its Metastasis via Antioxidation Activity.
Up-regulation of gelatinases in the colorectal adenoma-carcinoma sequence.
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Upregulated matrix metalloproteinase-2 and downregulated tissue factor pathway inhibitor-2 are risk factors for lymph node metastasis and perineural invasion in pancreatic carcinoma.
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
Upregulation of histamine receptor H1 promotes tumor progression and contributes to poor prognosis in hepatocellular carcinoma.
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis.
Uterine cervical carcinoma: Role of matrix metalloproteinases (Review).
Vascular endothelial growth factor-C expression and invasive phenotype in ovarian carcinomas.
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Video-rate bioluminescence imaging of matrix metalloproteinase-2 secreted from a migrating cell.
Vinorelbine cationic liposomes modified with wheat germ agglutinin for inhibiting tumor metastasis in treatment of brain glioma.
Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: potential anti-tumor effect in cancer invasion and metastasis.
Visfatin Promotes the Metastatic Potential of Chondrosarcoma Cells by Stimulating AP-1-Dependent MMP-2 Production in the MAPK Pathway.
WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression.
Wip1 is associated with tumorigenity and metastasis through MMP-2 in human intrahepatic cholangiocarcinoma.
Wnt signaling pathway inhibitors as promising diagnostic serum markers of osteolytic bone metastasis.
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors.
Xiao Han, et al., GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies. Molecules, 2012, 17, 1357-1372.
XRCC1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis through suppressing MMP-2 and MMP-9.
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.
Zoledronic acid exhibits inhibitory effects on osteoblastic and osteolytic metastases of prostate cancer.
Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis.
[An experimental research on tumor metastasis treated by chicken homologous matrix metalloproteinase-2 vaccine combined with low-dose cisplatin]
[Analysis of the mechanism of trophoblast infiltration]
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
[Clinical significance and relationship of expression of matrix metalloproteinase-2 mRNA with breast cancer metastasis.]
[Clinical significance of matrix metalloproteinase-2 expression in patients with epithelial ovarian tumor]
[Collagenases and cancers]
[Construction and secretory expression of single-chain Fv fragment M97 with therapeutic potential against tumor invasion and metastasis]
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
[Correlation between expression of MMP-2, MMP-9, TIMP-2, TIMP-1 and metastasis of neuroblastoma]
[Correlation between matrix metalloproteinases-2 and tissue inhibitor of metalloproteinase-2 expression, metastatic potential and tumor angiogenesis in synovial sarcoma and its prognostic significance]
[Correlation of expression of vascular endothelial growth factor and matrix matalloproteinase-2 to invasion of ovarian tumor cells in vitro]
[Correlation of tenascin-C degradation fragment with recurrence and/or metastasis in early non-small-cell lung cancer]
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]
[Effect of cyclooxygenase-2,and matrix metalloproteinase-2 expression on prognosis of lung cancer]
[Effect of hypoxia on infiltration and migration of lung cancer cells and expression of MMP-2 and TIMP-2.]
[Effect of long noncoding RNA SPRY4-IT1 on proliferation and metastasis of medulloblastoma].
[Effect of RNAi-mediated STAT3 gene inhibition on metastasis of human pancreatic cancer cells]
[Effect of tumor-associated macrophages on invasion and metastasis of gastric cancer cells].
[Effects of dihydromyricetin on the migration and invasion of human gastric cancer MKN45 cells and its mechanism].
[Enhancement effects of hypoxia on invasion and metastasis of K562 cells]
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
[Expression and clinicopathologic significance of OPN, CD44v6 and MMP-2 in squamous cell carcinoma and adenocarcinoma of the lung].
[Expression and pathological mechanism of MMP-9 and HIF-2? in CD133(+) lung cancer stem cells].
[Expression of CD147, matrix metalloproteinases and transforming growth factor beta1 in breast cancer]
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
[Expression of matrix metalloproteinase-2 and insulin-like growth factor-1 in gastric carcinoma and their clinicopathological significance].
[Expression of matrix metalloproteinase-2 in hypopharyngeal carcinoma and its clinical significance]
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
[Expression of matrix metalloproteinase-2,9 in hypopharyngeal carcinoma and its relationship with lymphatic metastasis]
[Expression of matrix metalloproteinase-2,matrix metalloproteinase-9 and vascular endothdial growth factor in retinoblastoma and its clinical significance.]
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
[Expression of MMP-2 and E-CD in salivary mucoepidermoid carcinoma and its correlation with infiltration, metastasis and prognosis]
[Expression of MMP-2 and its clinical significance in cervical squamous carcinoma]
[Expression of MMP-2, MMP-9, TIMP-1 and their relationship with prognosis in NSCLC.]
[Expression of nm23/NDPK, integrin, type IV collagenase and uPA in transplanted tumors with various metastatic potential in nude mice and surgical specimens]
[Expression of TGF-beta1 and the mechanism of invasiveness and metastasis induced by TGF-beta1 in breast cancer]
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
[Expressions of COX-2 and MMP-2 in nasopharyngeal carcinoma and the their relationship with lymph node metastasis]
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
[Expressions of vascular endothelial growth factor C and matrix metalloproteinases-2 and prognosis of non-small cell lung carcinoma.]
[FABP5 promotes cell growth, invasion and metastasis in cervical cancer].
[Gene expressions of type IV collagenase and tissue inhibitor of metalloproteinases (TIMP) in human bladder cancers]
[Helicobacter pylori infection, the invasion and metastasis of the gastric carcinoma, and the expression of MMP-2 and TIMP-2]
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
[Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro]
[Inhibitory effect of endoplasmic reticulum-retained anti-type IV collagenase intrabody on invasion and proliferation of cancer cell]
[Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3]
[Key enzymes of degradation and angiogenesis as a factors of tumor progression in squamous cell carcinoma of the cervix].
[Matrix metalloproteinase 2 and 9 as the factor of head and neck tumor metastasis]
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
[Metastatic ability and type IV collagenase expression of oncogene-transformed human bronchial epithelial cells]
[Minocycline potentiates the antimetastatic effect of boanmycin]
[MMP-2 expression (type IV collagenase) in gastric cancer]
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
[Molecular biology studies on metalloproteinase and tissue inhibitor of metalloproteinase expression in salivary adenoid cystic carcinoma]
[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1]
[Prognostic value of serum MMP-2 level in uterine cancer affected women]
[Progress of clinical pathology and application of PET-CT on thyroid carcinoma]
[Promotion of MAG-1 on Metastasis of Lung Cancer Cells in vitro and Its Expression in Lung Cancer Tissue of 24 Cases.]
[Regulation of matrix-degrading enzymes in gynecologic cancer tissues and cells]
[Relationship between expression of MMP-2 and prognosis in human laryngeal squamous cell carcinoma].
[Relationship between serum matrix metalloproteinase-2 and metastasis and recurrence following radical hepatic resection in hepatocellular carcinoma]
[Role of matrix metalloproteinase (MMP)-2 and -9 and vascular endothelial growth factor C in lymph node metastasis of breast cancer.]
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
[Short hairpin RNA-mediated suvivin gene silencing inhibits invasion and metastasis of human colon carcinoma cell line SW480 in vitro]
[Significance of caveolin-1 protein detected by quantum dots technique in human lung cancer invasiveness and metastasis.]
[SRC kinase inhibitor PP2 inhibits invasion and metastasis of lung cancer A549 cells by upregulating connexin43 expression].
[Study of matrix metalloproteinase-2 and -9 in thyroid papillary cancer]
[Study of type I and IV collagenase activity in human thyroid diseases]
[Study on expression of matrix metalloproteinases and their inhibitors in parotid gland tumors]
[The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas]
[The effects of MMPs and TIMPs on the metastasis of oral squamous cell carcinoma to neck lymph nodes]
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
[The expression of MMP-2, E-cadherin in supraglottic carcinoma and their relationship with cervical lymph nody metastasis]
[The matrix metalloproteinase in oral and oropharyngeol cancer - literature review].
[The mechanisms of microenvironments influence on vasculogenic mimicry between introcular and subcutaneous melanoma]
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
[The Role and Mechanism of CXCR4 and Its Ligand SDF-1 in the Development of Cervical Cancer Metastasis.]
[The role of CXCR4 in lung cancer metastasis and its possible mechanism]
[The role of MMP-2 in the invasion and metastasis of hepatocellular carcinoma (HCC)]
[The serum concentration of metalloproteinase 9 and 2 in non-small cell lung cancer patients]
[Type IV collagenase activities in human colorectal cancers and its role in cancer invasion and metastasis]
[Type IV collagenase activities in human colorectal carcinomas and its role in hepatic metastasis: preliminary report]
[Type IV collagenase expression in human prostate carcinoma cell lines with different metastasis potentials]
Neoplasm Micrometastasis
A third-generation matrix metalloproteinase (MMP) inhibitor (ONO-4817) combined with docetaxel suppresses progression of lung micrometastasis of MMP-expressing tumor cells in nude mice.
Differential expression of matrix metalloproteinase-2 expression in disseminated tumor cells and micrometastasis in bone marrow of patients with nonmetastatic and metastatic prostate cancer: theoretical considerations and clinical implications-an immunocytochemical study.
Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
[Detection of micrometastases in sentinel lymph nodes of breast cancer]
Neoplasm, Residual
Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition.
The expression and activity of MMPs are increased in residual tumor tissues after the termination of immunotherapy.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Neoplasms
'Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer'.
(-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis.
(-)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats.
(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone.
1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation InVivo and In Vitro Model.
1Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers.
2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione inhibits the growth and metastasis of breast carcinoma in mice.
3,5-Dicaffeoyl-epi-quinic acid inhibits the PMA-stimulated activation and expression of MMP-9 but not MMP-2 via downregulation of MAPK pathway.
4-HPR impairs bladder cancer cell migration and invasion by interfering with the Wnt5a/JNK and Wnt5a/MMP-2 signaling pathways.
72-kilodalton type IV collagenase, type IV collagen, and Ki 67 antigen in serous tumors or the ovary: a clinicopathologic, immunohistochemical, and Serological study.
92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma.
?-Solanine inhibits human melanoma cell migration and invasion by reducing matrix metalloproteinase-2/9 activities.
?3GnT8 plays an important role in CD147 signal transduction as an upstream modulator of MMP production in tumor cells.
?3GnT8 Regulates Laryngeal Carcinoma Cell Proliferation Via Targeting MMPs/TIMPs and TGF-?1.
A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells.
A case for the use of receiver operating characteristic analysis of potential clinical efficacy biomarkers in advanced renal cell carcinoma.
A chimera of a gelatinase inhibitor peptide with streptavidin as a bifunctional tumor targeting reagent.
A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide.
A Co-Culture System of Three-Dimensional Tumor-Associated Macrophages and Three-Dimensional Cancer-Associated Fibroblasts Combined with Biomolecule Release for Cancer Cell Migration.
A Combined Approach Employing Chlorotoxin-Nanovectors and Low Dose Radiation To Reach Infiltrating Tumor Niches in Glioblastoma.
A comparative study of MMP-1, MMP-2, and TNF-? expression in different acne vulgaris lesions.
A comparison of ocular melanocyte and uveal melanoma cell invasion and the implication of alpha1beta1, alpha4beta1 and alpha6beta1 integrins.
A comparison of the biological features between prostate cancers arising in the transition and peripheral zones.
A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging.
A conjugate of camptothecin and a somatostatin analog against prostate cancer cell invasion via a possible signaling pathway involving PI3K/Akt, alphaVbeta3/alphaVbeta5 and MMP-2/-9.
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
A dual-functional magnetic microsphere for ICP-MS quantification and fluorescence imaging of matrix metalloproteinase 2 in cell secretion.
A Fluorescent Gelatin Degradation Assay to Study Melanoma Breakdown of Extracellular Matrix.
A functional polymorphism in the matrix metalloproteinase-2 gene promoter (-1306C/T) is associated with risk of development but not metastasis of gastric cardia adenocarcinoma.
A gelatin in situ-overlay technique localizes brain matrix metalloproteinase activity in experimental focal cerebral ischemia.
A hepatic invasive human colorectal xenograft model.
A high serum matrix metalloproteinase-2 level is associated with an adverse prognosis in node-positive breast carcinoma.
A High-Cholesterol Diet Increases Toll-like Receptors and Other Harmful Factors in the Rabbit Myocardium: The Beneficial Effect of Statins.
A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng.
A Mathematical Framework for Modelling the Metastatic Spread of Cancer.
A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo.
A matrix metalloproteinase expressed on the surface of invasive tumour cells.
A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Suppresses Cell Migration and Invasion in Monomorphic Malignant Human Glioma Cells by Inhibiting FAK/STAT3 Signaling.
A Multi-functional Vector for delivery of Genome Editing Plasmid Targeting ?-Catenin to Re-modulate Cancer Cell Properties.
A multicentre cohort study of serum and peritoneal biomarkers to predict anastomotic leakage after rectal cancer resection.
A multiplicity of anti-invasive effects of farnesyl transferase inhibitor SCH66336 in human head and neck cancer.
A New Histone Deacetylase Inhibitor, MHY219, Inhibits the Migration of Human Prostate Cancer Cells via HDAC1.
A Novel MMP-2 Inhibitor 3-azidowithaferin A (3-azidoWA) Abrogates Cancer Cell Invasion and Angiogenesis by Modulating Extracellular Par-4.
A Novel Role of Cab45-G in Mediating Cell Migration in Cancer Cells.
A novel strategy for designing specific gelatinase A inhibitors: potential use to control tumor progression.
A Novel Synthetic Compound (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile Inhibits TNF?-Induced MMP9 Expression via EGR-1 Downregulation in MDA-MB-231 Human Breast Cancer Cells.
A novel tripeptide, tyroserleutide, inhibits irradiation-induced invasiveness and metastasis of hepatocellular carcinoma in nude mice.
A nutrient mixture inhibits glioblastoma xenograft U-87 MG growth in male nude mice.
A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin.
A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial-mesenchymal transition via the canonical Wnt/?-catenin signaling pathway.
A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2.
A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging.
A quantitative evaluation of active gelatinolytic sites in uterine endometrioid adenocarcinoma using film in situ zymography: association of stronger gelatinolysis with myometrial invasion.
A quicker degradation rate is yielded by a novel kind of transgenic silk fibroin consisting of shortened silk fibroin heavy chains fused with matrix metalloproteinase cleavage sites.
A role for AP-1 in matrix metalloproteinase production and invadopodia formation of v-Crk-transformed cells.
A role for endothelial-derived matrix metalloproteinase-2 in breast cancer cell transmigration across the endothelial-basement membrane barrier.
A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells.
A single nucleotide polymorphism in the matrix metalloproteinase 2 promoter is closely associated with high risk of nasopharyngeal carcinoma in Cantonese from southern China.
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration.
A size-shrinkable matrix metallopeptidase-2-sensitive delivery nanosystem improves the penetration of human programmed death-ligand 1 siRNA into lung-tumor spheroids.
A Smart Photosensitizer-Cerium Oxide Nanoprobe for Highly Selective and Efficient Photodynamic Therapy.
A Study of Matrix Metalloproteinase-2 and Interleukin-18 in Preinvasive and Invasive Lesions of Cancer Cervix.
A study on angiogenesis-related matrix metalloproteinase networks in primary hepatocellular carcinoma.
A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription.
A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1? nuclear translocation and its target gene activation against neoplastic progression.
Aberrant expression of clock gene period1 and its correlations with the growth, proliferation and metastasis of buccal squamous cell carcinoma.
Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy via regulation of matrix metalloproteinase 2 expression.
Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis.
Accumulation of extracellular matrix in the liver induces high metastatic potential of hepatocellular carcinoma to the lung.
Acidic mucopolysaccharide from Holothuria Leucospilota has antitumor effect by inhibiting angiogenesis and tumor cell invasion in vivo and in vitro.
ACPI Conjugated Gold Nanorods as Nanoplatform for Dual Image Guided Activatable Photodynamic and Photothermal Combined Therapy In Vivo.
ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis.
Actinidia callosa var. callosa suppresses metastatic potential of human hepatoma cell SK-Hep1 by inhibiting matrix metalloproteinase-2 through PI3K/Akt and MAPK signaling pathways.
Activatable T1 Relaxivity Recovery Nanoconjugates for Kinetic and Sensitive Analysis of Matrix Metalloprotease 2.
Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity.
Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation.
Activated matrix metalloproteinase-2--a potential marker of prognosis for epithelial ovarian cancer.
Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells.
Activation of EDTA-resistant gelatinases in malignant human tumors.
Activation of fibroblast-derived matrix metalloproteinase-2 by colon-cancer cells in non-contact Co-cultures.
Activation of human umbilical vein endothelial cell progelatinase A by phorbol myristate acetate: a protein kinase C-dependent mechanism involving a membrane-type matrix metalloproteinase.
Activation of Large form Galanin-LI by Extracellular Processing in Small Cell Lung Carcinoma Tissue.
Activation of matrix metalloproteinase (MMP)-2 by membrane type 1-MMP and abnormal immunolocalization of the basement membrane components laminin and type IV collagen in canine spontaneous hemangiosarcomas.
Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.
Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species.
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Activation of matrix metalloproteinase-2 is correlated with invasiveness in thymic epithelial tumors.
Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent.
Activation of progelatinase A (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: a role for inflammatory cells in tumor invasion and angiogenesis.
Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2).
Activation of Snail and EMT-Like Signaling via the IKK??/NF-?B Pathway in Apicidin-Resistant HA22T Hepatocellular Carcinoma Cells.
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis.
Activation of toll-like receptor-2 by endogenous matrix metalloproteinase-2 modulates dendritic-cell-mediated inflammatory responses.
Activation of tumor cell matrix metalloproteinase-2 by neutrophil proteinases requires expression of membrane-type 1 matrix metalloproteinase.
Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma.
Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.
Activation State of Stromal Inflammatory Cells in Murine Metastatic Pancreatic Adenocarcinoma.
Activator Protein-2? Promotes Tumor Growth and Predicts Poor Prognosis in Breast Cancer.
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Active immunogene therapy of cancer with vaccine on the basis of chicken homologous matrix metalloproteinase-2.
Active matrix metalloproteinase-2 activity discriminates colonic mucosa, adenomas with and without high-grade dysplasia, and cancers.
Active MMP-2 effectively identifies the presence of colorectal cancer.
Active targeted drug delivery of MMP-2 sensitive polymeric nanoparticles.
Activities and polymorphisms of MMP-2 and MMP-9, smoking, diabetes and risk of prostate cancer.
Activity and cellular origin of gelatinases in patients with colon and rectal carcinoma differential activity of matrix metalloproteinase-9.
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Activity of matrix metalloproteinase-2 (MMP-2) in canine oronasal tumors.
Activity of matrix metalloproteinases-2 and -9 in advanced laryngeal cancer.
Activity of MMP-2 and MMP-9 in sera of breast cancer patients.
Activity of type IV collagenases (MMP-2 and MMP-9) in primary pulmonary carcinomas: a quantitative analysis.
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis, and increased tumor growth.
Adapting and Remolding: Orchestrating Tumor Microenvironment Normalization with Photodynamic Therapy by Size Transformable Nanoframeworks.
Addition of matrix metalloproteinase inhibition to conventional cytotoxic therapy reduces tumor implantation and prolongs survival in a murine model of human pancreatic cancer.
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
Adenovirus E1A represses protease gene expression and inhibits metastasis of human tumor cells.
Adenovirus-mediated ING4 expression suppresses lung carcinoma cell growth via induction of cell cycle alteration and apoptosis and inhibition of tumor invasion and angiogenesis.
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice.
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma.
Adhesive and invasive features in gliomas.
Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar.
Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression.
Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells.
Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model.
Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines.
Alkaloid and phenolic compounds of Xylopia aromatica inhibits tumor growth by down-regulating matrix metalloproteinase-2 (MMP-2) expression.
All-Trans Retinoic Acid Enhances Matrix Metalloproteinase 2 Expression and Secretion in Human Myeloid Leukemia THP-1 Cells.
alpha v beta3-dependent cross-presentation of matrix metalloproteinase-2 by melanoma cells gives rise to a new tumor antigen.
alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells.
Alteration of MMP-2 and -14 expression by imatinib in HPV-positive and -negative squamous cell carcinoma.
Alteration of the Methylation Status of Tumor-Promoting Genes Decreases Prostate Cancer Cell Invasiveness and Tumorigenesis In vitro and In vivo.
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Altered transcriptional regulation of human interstitial collagenase in cultured skin fibroblasts from older donors.
Alternagin-C binding to ?2?1 integrin controls matrix metalloprotease-9 and matrix metalloprotease-2 in breast tumor cells and endothelial cells.
Alternative pathway for the role of furin in tumor cell invasion process. Enhanced MMP-2 levels through bioactive TGFbeta.
Aluminum naphthalocyanine conjugate as an MMP-2-activatable photoacoustic probe for in vivo tumor imaging.
Ameloblastic neoplasia spectrum: a cross-sectional study of MMPS expression and proliferative activity.
Amentoflavone Inhibits Experimental Tumor Metastasis Through a Regulatory Mechanism Involving MMP-2, MMP-9, Prolyl Hydroxylase, Lysyl Oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and Cytokines in Lung Tissues of C57BL/6 Mice.
Ampelopsin suppresses TNF-?-induced migration and invasion of U2OS osteosarcoma cells.
Amplified and label-free electrochemical detection of a protease biomarker by integrating proteolysis-triggered transcription.
An animal model for colon cancer metastasis: establishment and characterization of murine cell lines with enhanced liver-metastasizing ability.
An Au-Se nanoprobe for the evaluation of the invasive potential of breast cancer cells via imaging the sequential activation of uPA and MMP-2.
An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells.
An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection.
An in vivo model for screening peptidomimetic inhibitors of gelatinase A.
An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.
An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines.
An MMP-2 Responsive Liposome Integrating Antifibrosis and Chemotherapeutic Drugs for Enhanced Drug Perfusion and Efficacy in Pancreatic Cancer.
An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment.
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Analysis of the capillary architecture in the precursors of prostate cancer: recent findings and new concepts.
Analysis of tumor-infiltrating gamma delta T cells in rectal cancer.
Andrographolide enhances the anti-metastatic effect of radiation in Ras-transformed cells via suppression of ERK-mediated MMP-2 activity.
Angiogenesis and tumor growth inhibition by a matrix metalloproteinase inhibitor targeting radiation-induced invasion.
Angiogenesis in neuroblastoma.
Angiogenesis in renal cell carcinoma: Evaluation of microvessel density, vascular endothelial growth factor and matrix metalloproteinases.
Angiogenesis in vestibular schwannomas: expression of extracellular matrix factors MMP-2, MMP-9, and TIMP-1.
Angiogenin contributes to bladder cancer tumorigenesis by DNMT3b-mediated MMP2 activation.
Angiopep-2 and activatable cell penetrating peptide dual modified nanoparticles for enhanced tumor targeting and penetrating.
Angiopoietin 2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice.
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway.
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2.
Angiotensin II-induced MMP-2 release from endothelial cells is mediated by TNF-alpha.
Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer.
Annexin A3 Knockdown Suppresses Lung Adenocarcinoma.
Annexin II promotes invasion and migration of human hepatocellular carcinoma cells in vitro via its interaction with HAb18G/CD147.
Anthocyanins from the Fruit of Vitis Coignetiae Pulliat Inhibit TNF-Augmented Cancer Proliferation, Migration, and Invasion in A549 Cells
Anti-beta4 integrin antibodies enhance migratory and invasive abilities of human colon adenocarcinoma cells and their MMP-2 expression.
Anti-cancer effect of metformin on the metastasis and invasion of primary breast cancer cells through mediating NF-kB activity.
Anti-inflammatory and anti-oxidant properties of Schisandrin C promote mitochondrial biogenesis in human dental pulp cells.
Anti-inflammatory effects of shikonin in human periodontal ligament cells.
Anti-invasion and anti-tumor growth effect of doxycycline treatment for human oral squamous-cell carcinoma--in vitro and in vivo studies.
Anti-metastatic and anti-angiogenic activities of sulfated polysaccharide of Sepiella maindroni ink
Anti-metastatic and anti-angiogenic activities of sulfated polysaccharide of Sepiella maindroni ink.
Anti-metastatic effect of deoxyelephantopin from Elephantopus scaber in A549 lung cancer cells in vitro.
Anti-Metastatic Effects of Antrodan with and without Cisplatin on Lewis Lung Carcinomas in a Mouse Xenograft Model.
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells.
Anti-proliferative effects of mesenchymal stem cells (MSCs) derived from multiple sources on ovarian cancer cell lines: an in-vitro experimental study.
Anti-tubulin agent vinorelbine inhibits metastasis of cancer cells by regulating epithelial-mesenchymal transition.
Anti-tumor effects of mfn2 in gastric cancer.
Antiangiogenic activity of selenium in cancer chemoprevention: metabolite-specific effects.
Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo.
Anticancer effect of lysine, proline, arginine, ascorbic acid and green tea extract on human renal adenocarcinoma line 786-0.
Anticancer Efficacy of Polyphenols and Their Combinations.
Anticancer mechanisms of YC-1 in human lung cancer cell line, NCI-H226.
Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice.
Antimetastatic effects of gambogic acid are mediated via the actin cytoskeleton and NF-?B pathways in SK-HEP1 cells.
Antimetastatic Potentials of Phyllanthusurinaria L on A549 and Lewis Lung Carcinoma Cells via Repression of Matrix-Degrading Proteases.
Antineoplastic effect of intracellular expression of a single-chain antibody directed against type IV collagenase.
Antisense Deoxyoligonucleotides Inhibit Activities of Matrix Metalloproteinase-2 in Human Fibrosarcoma HT1080 Cells.
Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma.
Antitumor activity of triptolide in SKOV3 cells and SKOV3/DDP in vivo and in vitro.
Antitumor and antimetastatic actions of dihydroxycoumarins (esculetin or fraxetin) through the inhibition of M2 macrophage differentiation in tumor-associated macrophages and/or G1 arrest in tumor cells.
Antitumor and antimetastatic activities of Rhizoma Paridis saponins.
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Antitumor effects of aconitine in A2780 cells via estrogen receptor ??mediated apoptosis, DNA damage and migration.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Antitumor effects of recombinant human adenovirus-p53 against human cutaneous squamous cell carcinoma in mice.
Antitumor effects of the molecule-downsized immunoconjugate composed of lidamycin and Fab' fragment of monoclonal antibody directed against type IV collagenase.
Antitumor efficacy of hypothemycin, a new Ras-signaling inhibitor.
Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells.
Antitumor evaluation of carboxymethyl chitosan based norcantharidin conjugates against gastric cancer as novel polymer therapeutics.
Antitumor progression potential of morusin suppressing STAT3 and NF?B in human hepatoma SK-Hep1 cells.
Antiulcer activity of anthocyanins from Rubus coreanus via association with regulation of the activity of matrix metalloproteinase-2.
Apigenin Attenuates Insulin-Like Growth Factor-I Signaling in an Autochthonous Mouse Prostate Cancer Model.
Areca nut alkaloids induce irreparable DNA damage and senescence in fibroblasts and may create a favourable environment for tumour progression.
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
Arsenic trioxide (As(2)O(3)) inhibits peritoneal invasion of ovarian carcinoma cells in vitro and in vivo.
Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo.
Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors.
Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells.
ASSESSMENT OF GELATINASE AND TUMOR NECROSIS FACTOR-? LEVEL IN THE VITREOUS AND SERUM OF PATIENTS WITH EALES DISEASE: Role of Inflammation-Mediated Angiogenesis in the Pathogenesis of Eales Disease.
Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography.
Assessment of indirect hemagglutination and zymography procedures in evaluation of gelatinase a in patients with benign and malignant prostate hyperplasia.
Assessment of MicroRNA (miR)-365 Effects on Oral Squamous Carcinoma Cell Line Phenotypes.
Assessment of the clinical significance of serum matrix metalloproteinases MMP-2 and MMP-9 in patients with various chronic liver diseases and hepatocellular carcinoma.
Assessment of the Inhibitory Effects of Ficin-hydrolyzed Gelatin Derived from Squid (Uroteuthis duvauceli) on Breast Cancer Cell Lines and Animal Model.
Assessment of the involvement of the macrophage migration inhibitory factor-glucocorticoid regulatory dyad in the expression of matrix metalloproteinase-2 during periodontitis.
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer.
Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma.
Association between MMP-2 expression and prostate cancer: A meta-analysis.
Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma.
Association of cavernous malformation within vestibular schwannoma: immunohistochemical analysis of matrix metalloproteinase-2 and -9.
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer.
Association of E-cadherin, matrix metalloproteinases, and tissue inhibitors of metalloproteinases with the progression and metastasis of hepatocellular carcinoma.
Association of fibrotic remodeling and cytokines/chemokines content in epicardial adipose tissue with atrial myocardial fibrosis in patients with atrial fibrillation.
Association of increased phosphatidylinositol 3-kinase signaling with increased invasiveness and gelatinase activity in malignant gliomas.
Association of matrix metalloproteinase (MMP)-2 and -9 expression with extra-gastrointestinal stromal tumor metastasis.
Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese.
Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.
Association of MMP-2 expression and prognosis in osteosarcoma patients.
Association of single nucleotide polymorphisms of ?2-adrenergic receptor gene with clinicopathological features of pancreatic carcinoma.
Association of suppression of extracellular signal-regulated kinase phosphorylation by epigallocatechin gallate with the reduction of matrix metalloproteinase activities in human fibrosarcoma HT1080 cells.
Association of type II apoptosis and 92-kDa type IV collagenase expression in human amniochorion in prematurely ruptured membranes with tumor necrosis factor receptor-1 expression.
Associations between single nucleotide polymorphisms of COX-2 and MMP-2 genes and colorectal cancer susceptibility in the Saudi population.
Astrocytes directly influence tumor cell invasion and metastasis in vivo.
Asymmetric dimethylarginine as a useful risk marker of radial artery calcification in patients with advanced kidney disease.
Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma.
Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways.
Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization.
Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression.
Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.
Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10.
Attenuation of NDEA-induced hepatocarcinogenesis by naringenin in rats.
Au-Se-Bond-Based Nanoprobe for Imaging MMP-2 in Tumor Cells under a High-Thiol Environment.
Au-siRNA@ aptamer nanocages as a high-efficiency drug and gene delivery system for targeted lung cancer therapy.
Aurora-A modulates MMP-2 expression via AKT/NF-?B pathway in esophageal squamous cell carcinoma cells.
Autocrine factor enhancing the secretion of M(r) 95,000 gelatinase (matrix metalloproteinase 9) in serum-free medium conditioned with murine metastatic colon carcinoma cells.
Autocrine factors, type IV collagenase secretion and prostatic cancer cell invasion.
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma.
Baicalein inhibits inflammatory response and promotes osteogenic activity in periodontal ligament cells challenged with lipopolysaccharides.
Baicalein inhibits pulmonary carcinogenesis-associated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo.
Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium.
Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus.
Basement membrane and the SIKVAV laminin-derived peptide promote tumor growth and metastases.
Basement membrane patterns, gelatinase A and tissue inhibitor of metalloproteinase-2 expressions, and stromal fibrosis during the development of peripheral lung adenocarcinoma.
Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth.
Bcl-2 promotes invasion and lung metastasis by inducing matrix metalloproteinase-2.
BCRP expression in VX2 rabbit liver tumours and its effects on tumour recurrence, metastasis and treatment tolerability.
Behavior of murine renal carcinoma cells grown in ectopic or orthotopic sites in syngeneic mice.
Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration.
Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-?/VEGF/Rho-GTPases: pivotal role of STAT-3.
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide.
Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9.
Beta-endorphin ameliorates synovial cell hyperfunction in the collagen-induced arthritis rat model by specific downregulation of NF-kappa B activity.
Betulin, betulinic acid and butein are inhibitors of acetaldehyde-induced activation of liver stellate cells.
Binding affinities for sulfonamide inhibitors with matrix metalloproteinase-2 using a linear response method.
Binding of alpha2 monoclonal antibody to human cervical tumor cell (SiHa) surface alpha2beta1 integrin modulates MMP-2 activity.
Binding of alpha5 monoclonal antibody to cell surface alpha5beta1 integrin modulates MMP-2 and MMP-7 activity in B16F10 melanoma cells.
Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro.
Biobehavioral influences on matrix metalloproteinase expression in ovarian carcinoma.
Bioengineered Human Serum Albumin Fusion Protein as Target/Enzyme/pH Three-Stage Propulsive Drug Vehicle for Tumor Therapy.
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer.
Biomarkers Affected by Impact Severity during Osteochondral Injury.
Biomarkers of anticancer activity of R115777 (Tipifarnib, Zarnestra) in human breast cancer models in vitro.
Biphenyl substituted lysine derivatives as recognition elements for the matrix metalloproteinases MMP-2 and MMP-9.
Bit1 knockdown contributes to growth suppression as well as the decreases of migration and invasion abilities in esophageal squamous cell carcinoma via suppressing FAK-paxillin pathway.
Black tea polyphenol (theaflavin) downregulates MMP-2 in human melanoma cell line A375 by involving multiple regulatory molecules.
Blockade of endogenous tissue kallikrein aggravates renal injury by enhancing oxidative stress and inhibiting matrix degradation.
Blockade of Rho/Rho-associated coiled coil-forming kinase signaling can prevent progression of hepatocellular carcinoma in matrix metalloproteinase-dependent manner.
Blockade of vascular angiogenesis by Aspergillus usamii var. shirousamii-transformed Angelicae Gigantis Radix and Zizyphus jujuba.
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway.
BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK.
Bone marrow angiogenesis and plasma cell angiogenic and invasive potential in patients with active multiple myeloma.
Bone marrow angiogenesis in patients with active multiple myeloma.
Bone marrow-derived mesenchymal stem cell transplantation attenuates overexpression of inflammatory mediators in rat brain after cardiopulmonary resuscitation.
Bone sialoprotein binding to matrix metalloproteinase-2 alters enzyme inhibition kinetics.
Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation.
Bone sialoprotein, matrix metalloproteinase 2, and alpha(v)beta3 integrin in osteotropic cancer cell invasion.
Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells.
BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1? proteasomal degradation.
Breast cancer cells and bone marrow mesenchymal stromal cells: a regulated modulation of the breast tumor in the context of immune response.
Breast tumor cells transendothelial migration induces endothelial cell anoikis through extracellular matrix degradation.
Brg-1 is required for maximal transcription of the human matrix metalloproteinase-2 gene.
Bruton's Tyrosine Kinase (BTK) Inhibitor (Ibrutinib)?-Suppressed Migration and Invasion of Prostate Cancer.
BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9.
Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways.
c-jun cooperates with SV40 T-antigen to sustain MMP-2 expression in immortalized cells.
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
Cadmium-induced malignant transformation of human prostate epithelial cells.
Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity.
CAGE, a cancer/testis antigen, induces c-FLIP(L) and Snail to enhance cell motility and increase resistance to an anti-cancer drug.
CAGE, a cancer/testis antigen, induces c-FLIPL and Snail to enhance cell motility and increase resistance to an anti-cancer drug
Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells.
Calpains are required for invasive and metastatic potentials of human HCC cells.
Cambodian Phellinus linteus inhibits experimental metastasis of melanoma cells in mice via regulation of urokinase type plasminogen activator.
Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts.
Cancer vaccine with mimotopes of tumor-associated carbohydrate antigens.
Cancer-Specific Survival Stratification Derived from Tumor Expression of Tissue Inhibitor of Metalloproteinase-2 in Non-Metastatic Renal Cell Carcinoma.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Canine Dilated Cardiomyopathy: Diffuse Remodeling, Focal Lesions, and the Involvement of Macrophages and New Vessel Formation.
Canine TIMP-2: purification, characterization and molecular detection.
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity.
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
Carbamoylphosphonate matrix metalloproteinase inhibitors 3: in vivo evaluation of cyclopentylcarbamoylphosphonic acid in experimental metastasis and angiogenesis.
Carbamoylphosphonates Control Tumor Cell Proliferation and Dissemination by Simultaneously Inhibiting Carbonic Anhydrase IX and Matrix Metalloproteinase-2. Toward Nontoxic Chemotherapy Targeting Tumor Microenvironment (1).
Carcinoembryonic antigen and matrix metalloproteinase 2 serum and peritoneal washes concentration in staging and prognosis in colorectal cancer patients.
Cardiac Dysfunction in Association with Increased Inflammatory Markers in Primary Aldosteronism.
Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis.
Case of primary malignant hemangiopericytoma of the heart expressing basement membrane-degradable enzymes.
Catalyser-21(TM), a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis.
Cathepsin G and alpha 1-antichymotrypsin in the local host reaction to loosening of total hip prostheses.
Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity.
CCR7 Mediates TGF-?1-Induced Human Malignant Glioma Invasion, Migration, and Epithelial-Mesenchymal Transition by Activating MMP2/9 Through the Nuclear Factor KappaB Signaling Pathway.
CD133+ cancer stem-like cells promote migration and invasion of salivary adenoid cystic carcinoma by inducing vasculogenic mimicry formation.
CD147 and matrix metalloproteinase-2 protein expression as significant prognostic factors in esophageal squamous cell carcinoma.
CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas.
CD147, MMP-2, MMP-9 and MVD-CD34 are Significant Predictors of Recurrence After Liver Transplantation in Hepatocellular Carcinoma Patients.
CD151 in cancer progression and metastasis: a complex scenario.
CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation.
CD44(+) gastric cancer cells with stemness properties are chemoradioresistant and highly invasive.
CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts.
Celastrol inhibit the proliferation, invasion and migration of human cervical HeLa cancer cells through down-regulation of MMP-2 and MMP-9.
Celecoxib inhibits cell growth and modulates the expression of matrix metalloproteinases in human osteosarcoma MG-63 cell line.
Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer.
Cell membrane-associated MT1-MMP dependent activation of MMP-2 in SiHa (human cervical cancer) cells.
Cell membrane-associated MT1-MMP-dependent activation of pro-MMP-2 in A375 melanoma cells.
Cell surface associated alpha-L: -fucose moieties modulate human breast cancer neoplastic progression.
Cell surface binding and activation of gelatinase A induced by expression of membrane-type-1-matrix metalloproteinase (MT1-MMP).
Cell type specific interleukin-6 induced responses in tumor keratinocytes and stromal fibroblasts are essential for invasive growth.
Cell-based identification of natural substrates and cleavage sites for extracellular proteases by SILAC proteomics.
Cell-matrix interactions modulate 92-kD gelatinase expression by human bronchial epithelial cells.
Cell-Permeable, MMP-2 Activatable, Nickel Ferrite and His-Tagged Fusion Protein Self-Assembled Fluorescent Nanoprobe for Tumor Magnetic-Targeting and Imaging.
Cell-surface-associated tissue transglutaminase is a target of MMP-2 proteolysis.
Cellular adhesion pathways and metastatic potential of human melanoma.
Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9.
Cellular protein and mRNA expression patterns of matrix metalloproteinases-2, -3 and -9 in human breast cancer: correlation with tumour growth.
Ceramide inhibition of MMP-2 expression and human cancer bronchial cell invasiveness involve decreased histone acetylation.
Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia.
Changes in extracellular matrix in different stages of colorectal cancer and their effects on proliferation of cancer cells.
Changes in MMP-2, MMP-9, inflammation, blood coagulation and intestinal mucosal permeability in patients with active ulcerative colitis.
Changes of histology and expression of MMP-2 and nm23-H1 in primary and metastatic gastric cancer.
Changes to N-linked oligosaccharide chains of human serum immunoglobulin G and matrix metalloproteinase-2 with cancer progression.
Characterization of a von Hippel Lindau pathway involved in extracellular matrix remodeling, cell invasion, and angiogenesis.
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase.
Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer.
Characterization of phosphoglycerate kinase-1 expression of stromal cells derived from tumor microenvironment in prostate cancer progression.
Characterization of Spontaneous and TGF-?-Induced Cell Motility of Primary Human Normal and Neoplastic Mammary Cells In Vitro Using Novel Real-Time Technology.
Chelerythrine suppresses proliferation and metastasis of human prostate cancer cells via modulating MMP/TIMP/NF-?B system.
Chemical Composition of Pterospermum heterophyllum Root and its Anti-Arthritis Effect on Adjuvant-Induced Arthritis in Rats via Modulation of Inflammatory Responses.
Chemical design of a radiolabeled gelatinase inhibitor peptide for the imaging of gelatinase activity in tumors.
Chemically modified tetracyclines (CMT-3 and CMT-8) enable control of the pathologic remodellation of human aortic valve stenosis via MMP-9 and VEGF inhibition.
Chemo-Photothermal Combination Cancer Therapy with ROS Scavenging, Extracellular Matrix Depletion, and Tumor Immune Activation by Telmisartan and Diselenide-Paclitaxel Prodrug Loaded Nanoparticles.
Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer.
Chemoradiation in Lung Cancer: Effect on Levels of NGAL and Vitamin D in Serum.
Chitosan-alginate 3D scaffolds as a mimic of the glioma tumor microenvironment.
Chlorogenic Acid Decreases Malignant Characteristics of Hepatocellular Carcinoma Cells by Inhibiting DNMT1 Expression.
Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2.
Chlorotoxin-Conjugated Multifunctional Dendrimers Labeled with Radionuclide 131I for Single Photon Emission Computed Tomography Imaging and Radiotherapy of Gliomas.
Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs.
Chromodomain Helicase/ATPase DNA-Binding Protein 1-Like Gene (CHD1L) Expression and Implications for Invasion and Metastasis of Breast Cancer.
Chromosomal, epigenetic and microRNA-mediated inactivation of LRP1B, a modulator of the extracellular environment of thyroid cancer cells.
Chronic Exposure of Renal Stem Cells to Inorganic Arsenic Induces a Cancer Phenotype.
Chronic exposure to microcystin-LR increases the risk of prostate cancer and induces malignant transformation of human prostate epithelial cells.
Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells.
Chronic liver injury promotes hepatocarcinoma cell seeding and growth, associated with infiltration by macrophages.
Chronic stress promotes gastric cancer progression and metastasis: an essential role for ADRB2.
Chronic stress promotes oral cancer growth and angiogenesis with increased circulating catecholamine and glucocorticoid levels in a mouse model.
Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma via regulation of MMP/TIMP balance as therapeutic target.
Cinnamamide, an antitumor agent with low cytotoxicity acting on matrix metalloproteinase.
CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis.
Circulating gelatinases are not prognostic of treatment response and survival in locally advanced rectal cancer patients undergoing preoperative chemoradiotherapy.
Circulating sRAGE in the diagnosis of osteolytic bone metastasis.
Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression.
Circulating tumor cells from a 4-dimensional lung cancer model are resistant to cisplatin.
Cisplatin and 4-hexylresorcinol synergise to decrease metastasis and increase survival rate in an oral mucosal melanoma xenograft model: a preliminary study.
Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer.
Clinical and prognostic features of MMP-2 and VEGF in AEG patients.
Clinical and prognostic role of matrix metalloproteinase-2, -9 and their inhibitors in breast cancer and liver diseases: A review.
Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer.
Clinical Impact of MMP and TIMP Gene Polymorphisms in Gastric Cancer.
Clinical implications of HER-2/neu overexpression and proteolytic activity imbalance in breast cancer.
Clinical manifestations of atherosclerosis in an elderly population are related to plasma neopterin, NGAL and endothelin-1, but not to Chlamydia pneumoniae serology.
Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue.
Clinical Relevance of Increased Endothelial and Mesothelial Expression of Proangiogenic Proteases and VEGFA in the Omentum of Patients with Metastatic Ovarian High-Grade Serous Carcinoma.
Clinical role of MMP-2/TIMP-2 imbalance in hepatocellular carcinoma.
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Clinical significance of matrix metalloproteinase 2 and 9 in breast cancer.
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Clinical significance of matrix metalloproteinase-2 in endometrial cancer: A systematic review and meta-analysis.
Clinical significance of MMP-2 and MMP-9 in patients with oral cancer.
Clinical significance of plasma MMP-2 and MMP-9 levels as biomarkers for tumor expression in breast cancer patients in Egypt.
Clinical significance of SCCRO (DCUN1D1) in prostate cancer and its proliferation-inhibiting effect on Lncap cells.
Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression.
Clinical significance of serum levels of matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor (TIMP-2) in gastric cancer.
Clinical significance of serum MMP-2 and MMP-7 in patients with ovarian cancer.
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Clinical study of systemic chemotherapy combined with bronchoscopic interventional cryotherapy in the treatment of lung cancer.
Clinical Study of Tumor Angiogenesis and Perfusion Imaging Using Multi-slice Spiral Computed Tomography for Breast Cancer.
Clinicohistopathological implications of MMP/VEGF expression in retinoblastoma: a combined meta-analysis and bioinformatics analysis.
Clinicopathologic and Prognostic Significance of Gelatinase A in Tunisian Colorectal Cancer: A Case-Control Study.
Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer.
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Clinicopathologic significance of plasma matrix metalloproteinase-2 and -9 levels in patients with undifferentiated nasopharyngeal carcinoma.
Clinicopathological and biological significance of human voltage-gated proton channel Hv1 over-expression in breast cancer.
Clinicopathological assessment and quantitative estimation of the matrix metalloproteinases MMP-2 and MMP-7 and the inhibitors TIMP-1 and TIMP-2 in colorectal carcinoma tissue samples.
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Clinicopathological significance of matrix metalloproteinase 2 protein expression in patients with renal cell carcinoma: A case-control study and meta-analysis.
Clinicopathological Significance of Matrix Metalloproteinase-2 Protein Expression in Renal Cell Carcinoma Patients.
Clinicopathological significance of MMP-2 and its specific inhibitor TIMP-2 in gastric cancer.
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer.
Cloning of a 72 kDa matrix metalloproteinase (gelatinase) from chicken embryo fibroblasts using gene family PCR: expression of the gelatinase increases upon malignant transformation.
Cloning of canine IL-1ra, TNFR and TIMP-2.
CMT-3, a non-antimicrobial tetracycline (TC), inhibits MT1-MMP activity: relevance to cancer.
Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis.
Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance.
Co-regulated expression of matrix metalloproteinase-2 and transforming growth factor-beta in melanoma development and progression.
CO2 Pneumoperitoneum Effects on Molecular Markers of Tumor Invasiveness in SH-SY5Y Neuroblastoma Cells.
Coaxial extrusion bioprinted shell-core hydrogel microfibers mimic glioma microenvironment and enhance the drug resistance of cancer cells.
Cobalt chloride-induced hypoxia modulates the invasive potential and matrix metalloproteinases of primary and metastatic breast cancer cells.
Coexpression of glucose transporter 1 and matrix metalloproteinase-2 in human cancers.
Collagen induced MMP-2 activation in human breast cancer.
Collagen-based co-culture for invasive study on cancer cells-fibroblasts interaction.
Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts.
Collagenase IV and clusterin-modified polycaprolactone-polyethylene glycol nanoparticles for penetrating dense tumor tissues.
Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx.
Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.
Colony-stimulating factor-1 antibody reverses chemoresistance in human mcf-7 breast cancer xenografts.
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.
Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.
Colorectal Cancer and Mitochondrial Dysfunctions of the Adjunct Adipose Tissues: A Case Study.
Colorectal cancer or colon and rectal cancer? Clinicopathological comparison between colonic and rectal carcinomas.
Combination Efficacy of Astragalus membranaceus and Curcuma wenyujin at Different Stages of Tumor Progression in an Imageable Orthotopic Nude Mouse Model of Metastatic Human Ovarian Cancer Expressing Red Fluorescent Protein.
Combination of paclitaxel- and retinoic acid-incorporated nanoparticles for the treatment of CT-26 colon carcinoma.
Combination of pembrolizumab and 125I attenuates the aggressiveness of non-small cell lung cancer.
Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells.
Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells.
Combined delivery of salinomycin and docetaxel by dual-targeting gelatinase nanoparticles effectively inhibits cervical cancer cells and cancer stem cells.
Combined evaluation of matrix metalloproteinases and their inhibitors has better clinical utility in oral cancer.
Combined therapeutic effect and molecular mechanisms of metformin and cisplatin in human lung cancer xenografts in nude mice.
Combined treatment with serine protease inhibitor aprotinin and matrix metalloproteinase inhibitor Batimastat (BB-94) does not prevent invasion of human esophageal and ovarian carcinoma cells in vivo.
Comparative analysis of matrix metalloproteinases by immunocytochemistry, immunohistochemistry and zymography in human primary brain tumours.
Comparative Analysis of P63, Maspin and Matrix Metalloproteinase 2 Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of Salivary Glands.
Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study.
Comparative analysis of the expression of metalloproteases (MMP-2, MMP-9, MMP-11 and MMP-13) and the tissue inhibitor of metalloprotease 3 (TIMP-3) between previous negative biopsies and radical prostatectomies.
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
Comparative expression of matrix metalloproteinases in internal malignancies and paired cutaneous metastatic lesions.
Comparative study of MMP-2 (matrix metalloproteinase 2) immune expression in normal uterine cervix, intraepithelial neoplasias, and squamous cells cervical carcinoma.
Comparing biocompatibility of gingival fibroblasts and bacterial strains on a different modified titanium discs.
Comparison between the gastric cancer cell line MKN-45 and the high-potential peritoneal dissemination gastric cancer cell line MKN-45P.
Comparison of fibrin glue and Vicryl sutures in conjunctival autografting for pterygium surgery.
Comparison of matrix metalloproteinase expression between primary tumors with or without liver metastasis in pancreatic and colorectal carcinomas.
Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks.
Components of the RANK/RANKL/OPG system, IL-6, IL-8, IL-16, MMP-2, and calcitonin in the sera of patients with bone tumors.
Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma.
Comprehensively enhanced delivery cascade by transformable beaded nanofibrils for pancreatic cancer therapy.
Concentration of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in the serum of patients with benign and malignant thyroid tumours treated surgically.
Concomitant inhibition of epidermal growth factor and vascular endothelial growth factor receptor tyrosine kinases reduces growth and metastasis of human salivary adenoid cystic carcinoma in an orthotopic nude mouse model.
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Conjunctival expression of matrix metalloproteinase and pro-inflammatory cytokine genes following trichiasis surgery.
Constitutive expression of a 92-kD gelatinase (type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines.
Construction and clinical significance of a predictive system for prognosis of hepatocellular carcinoma.
Construction of a sensitive protease sensor with DNA-peptide conjugates for single-molecule detection of multiple matrix metalloproteinases.
Contribution of host MMP-2 and MMP-9 to promote tumor vascularization and invasion of malignant keratinocytes.
Contribution of in vitro comparison of colorectal carcinoma cells from primary and metastatic lesions to elucidation of mechanisms of tumor progression and response to anticancer therapy.
Contribution of Matrix Metalloproteinase-2 Promoter Genotypes to Nasopharyngeal Cancer Susceptibility and Metastasis in Taiwan.
Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes.
Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94).
Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.
Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.
Coordinate action of membrane-type matrix metalloproteinase -1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion.
Coordinate enhancement of gelatinase A mRNA and activity levels in human fibroblasts in response to breast-adenocarcinoma cells.
Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma.
Cooverexpression of ERBB1 and ERBB4 receptors predicts poor clinical outcome in pN+ oral squamous cell carcinoma with extranodal spread.
Core-Shell Distinct Nanodrug Showing On-Demand Sequential Drug Release To Act on Multiple Cell Types for Synergistic Anticancer Therapy.
Correlation and prognostic significance of MMP-2 and TFPI-2 differential expression in pancreatic carcinoma.
Correlation between B7-H3 expression and matrix metalloproteinases 2 expression in pancreatic cancer.
Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma.
Correlation between MMP2 expression in lung cancer tissues and clinical parameters: a retrospective clinical analysis.
Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas.
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Correlation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase expression in ileal carcinoids, lymph nodes and liver metastasis with prognosis and survival.
Correlation of matrix metalloproteinases-2 and -9 with proinflammatory cytokines in Guillain-Barré syndrome.
Correlation of RECK with matrix metalloproteinase-2 in regulation of trophoblast invasion of early pregnancy.
Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer.
Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma.
Correlation of tumor- and stromal-derived MT1-MMP expression with progression of human ovarian tumors in SCID mice.
Correlations of serum VEGF and MMP-2 levels with CLM in CRC patients and effects of TACE on their expressions.
Correspondence re: C. F. M. Sier et al., Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers. Clin. Cancer Res., 6: 2333-2340, 2000.
Correspondence re: N-B. Liabakk et al., matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res., 56: 190-196, 1966.
Corydalis hendersonii Hemsl. protects against myocardial injury by attenuating inflammation and fibrosis via NF-?B and JAK2-STAT3 signaling pathways.
Cracking the riddle of dedifferentiated liposarcoma: is EV-MDM2 a key?
Cranial burr hole with erythropoietin administration induces reverse arteriogenesis from the enriched extracranium.
Cratoxy formosum leaf extract inhibits proliferation and migration of human breast cancer MCF-7 cells.
Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment.
CSE1L/CAS, the cellular apoptosis susceptibility protein, enhances invasion and metastasis but not proliferation of cancer cells.
Cucurbitacin B Enhances the Anticancer Effect of Imatinib Mesylate Through Inhibition of MMP-2 Expression in MCF-7 and SW480 Tumor Cell Lines.
Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity.
Curcumin ameliorates left ventricular function in rabbits with pressure overload: inhibition of the remodeling of the left ventricular collagen network associated with suppression of myocardial tumor necrosis factor-alpha and matrix metalloproteinase-2 expression.
Curcumin exerts multiple suppressive effects on human breast carcinoma cells.
Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis.
Curcumin suppresses invasiveness and vasculogenic mimicry of squamous cell carcinoma of the larynx through the inhibition of JAK-2/STAT-3 signaling pathway.
Curcumin suppresses tumor necrosis factor-?-induced matrix metalloproteinase-2 expression and activity in rat vascular smooth muscle cells via the NF-?B pathway.
Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2.
Curcumol inhibits lung adenocarcinoma growth and metastasis via inactivation of PI3K/AKT and Wnt/ß-catenin pathway.
Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics.
CXCR4 and matrix metalloproteinase-2 are involved in mesenchymal stromal cell homing and engraftment to tumors.
CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.
Cyclic AMP decreases chemotaxis, invasiveness and lung colonization of H-ras transformed mouse fibroblasts.
Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells.
Cyclooxygenase-2 expression correlates with membrane-type-1 matrix metalloproteinase expression in colorectal cancer tissue.
Cyclooxygenase-2 inhibitor prevents radiation-enhanced infiltration of F98 glioma cells in brain of Fischer rat.
Cyclooxygenase-2 is associated with malignant phenotypes in human lung cancer.
Cyclophosphamide promotes pulmonary metastasis on mouse lung adenocarcinoma.
Cysteinyl leukotriene receptor type 1 antagonist montelukast protects against injury of blood-brain barrier.
Cystic vestibular schwannomas: a possible role of matrix metalloproteinase-2 in cyst development and unfavorable surgical outcome.
Cytokine and matrix metalloproteinase expression in pigmented villonodular synovitis may mediate bone and cartilage destruction.
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Cytokine, chemokine, and matrix metalloproteinase response after sulfur mustard injury to weanling pig skin.
Cytokine-mediated regulation of human leukocyte gelatinases and role in arthritis.
Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.
Cytokines and acute phase reactants during flare-up of contact allergy to gold.
Cytokines as prognstic tool in breast carcinoma.
Cytokines regulate gelatinase A and B (matrix metalloproteinase 2 and 9) activity in cultured rat astrocytes.
Cytokines regulate matrix metalloproteinases and migration in cardiac fibroblasts.
Cytokines, inducers and inhibitors modulate MMP-2 and MMP?9 secretion by human Fanconi anemia immortalized fibroblasts.
Cytokines, matrix metalloproteases, angiogenic and growth factors in tears of normal subjects and vernal keratoconjunctivitis patients.
Cytotoxic Fusicoccane-Type Diterpenoids from Streptomyces violascens Isolated from Ailuropoda melanoleuca Feces.
Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase.
Degradation of tenascin-C and activity of matrix metalloproteinase-2 are associated with tumor recurrence in early stage non-small cell lung cancer.
Dehydroandrographolide inhibits oral cancer cell migration and invasion through NF-?B-, AP-1-, and SP-1-modulated matrix metalloproteinase-2 inhibition.
Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.
Delivering wasp venom for cancer therapy.
Delphinidin suppresses PMA-induced MMP-9 expression by blocking the NF-?B activation through MAPK signaling pathways in MCF-7 human breast carcinoma cells.
Dendropanax dentiger (Harms) Merr. root and its major constituents exert therapeutic effect on adjuvant-induced arthritis in rats.
Density-dependent regulation of cell-surface association of matrix metalloproteinase-2 (MMP-2) in breast-carcinoma cells.
Depletion of Hepatic Macrophages Aggravates Liver Lesions Induced in Rats by Thioacetamide (TAA).
Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
Deregulation of collagen metabolism in human stomach cancer.
Derlin-1 Is Overexpressed in Non-Small Cell Lung Cancer and Promotes Cancer Cell Invasion via EGFR-ERK-Mediated Up-Regulation of MMP-2 and MMP-9.
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples.
Design and Proof of Programmed 5-Aminolevulinic Acid Prodrug Nanocarriers for Targeted Photodynamic Cancer Therapy.
Design and synthesis of MMP inhibitors with appended fluorescent tags for imaging and visualization of matrix metalloproteinase enzymes.
Design of (99m) Tc-DTPA-CLP and preliminary evaluation in rats.
Design of radiolabeled gelatinase inhibitor peptide ((99m)Tc-CLP) and evaluation in rats.
Desmoplastic basal cell carcinomas possess unique basement membrane-degrading properties.
Desmoplastic response in scirrhous gastric carcinoma: imbalance between collagen synthesis and degradation.
Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.
Detection and Molecular Staging of Bladder Cancer Using Real-Time RT-PCR for Gelatinases (MMP-2, MMP-9) and TIMP-2 in Peripheral Blood.
Detection of differentially expressed gelatinase A in metastatic and non-metastatic subpopulations of tumor cells by target RNA arbitrarily primed polymerase chain reaction (TRAP-PCR).
Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy.
Detection of matrix metalloproteinases in canine mammary tumours: analysis by immunohistochemistry and zymography.
Detection of migration of locally implanted AC133+ stem cells by cellular magnetic resonance imaging with histological findings.
Detection of MMP-2 and MMP-9 Activity in Vivo with a Triple-Helical Peptide Optical Probe.
Detection of osteoarthritis in dogs by metabolic, pro-inflammatory and degenerative synovial fluid biomarkers and traditional radiographic screening: A pilot study.
Detection of serum MMPs in tumor-bearing hamsters.
Detection of type IV collagenase activity in malignant ascites.
Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters.
Determination of imbalance between MMP-2 and TIMP-2 in human neuroblastoma by reverse-transcription polymerase chain reaction and its correlation with tumor progression.
Development of a biomarker panel to predict cardiac resynchronization therapy response: Results from the SMART-AV trial.
Development of a gene/drug dual delivery system for brain tumor therapy: potent inhibition via RNA interference and synergistic effects.
Development of a Novel PET Tracer [18F]AlF-NOTA-C6 Targeting MMP2 for Tumor Imaging.
Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade.
Development of an aptamer-conjugated fluorescent nanoprobe for MMP2.
Development of anti-matrix metalloproteinase-2 (MMP-2) nanobodies as potential therapeutic and diagnostic tools.
Development of MRI/NIRF 'activatable' multimodal imaging probe based on iron oxide nanoparticles.
Development of Novel Animal Model for Studying Scoliosis Using a Noninvasive Method and Its Validation through Gene-Expression Analysis.
Development of upconversion nanoparticle-conjugated indium phosphide quantum dot for matrix metalloproteinase-2 cancer transformation sensing.
Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium.
Dexmedetomidine enhances hypoxia-induced cancer cell progression.
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1?/ TGF-?.
Diagnostic Power of Cytokine M-CSF, Metalloproteinase 2 (MMP-2) and Tissue Inhibitor-2 (TIMP-2) in Cervical Cancer Patients Based on ROC Analysis.
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Diethyldithiocarbamate prolongs survival of mice in a lipopolysaccharide-induced endotoxic shock model: evidence for multiple mechanisms.
Differences between brainstem gliomas in juvenile and adult rats.
Different expression patterns of MMP-2 and MMP-9 in breast cancer.
Different mRNA and protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 in benign and malignant prostate tissue.
Different patterns of gelatinolytic activity in pituitary macro- and microadenomas.
Different Protein Expressions between Peripheral Ameloblastoma and Oral Basal Cell Carcinoma Occurred at the Same Mandibular Molar Area.
Differential effects of trichostatin A on gelatinase A expression in 3T3 fibroblasts and HT-1080 fibrosarcoma cells: implications for use of TSA in cancer therapy.
Differential effects of tumor necrosis factor-? on matrix metalloproteinase-2 expression in human myometrial and uterine leiomyoma smooth muscle cells.
Differential expression and activity status of MMP-1, MMP-2 and MMP-9 in tumor and stromal cells of squamous cell carcinomas of the lung.
Differential expression and origin of membrane-type 1 and 2 matrix metalloproteinases (MT-MMPs) in association with MMP2 activation in injured human livers.
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis.
Differential expression of matrix metalloproteinase-2 by fibroblasts in co-cultures with keratinocytes, basal cell carcinoma and melanoma.
Differential expression of matrix metalloproteinase-2 expression in disseminated tumor cells and micrometastasis in bone marrow of patients with nonmetastatic and metastatic prostate cancer: theoretical considerations and clinical implications-an immunocytochemical study.
Differential expression of matrix metalloproteinases 2 and 9 by glial Müller cells: response to soluble and extracellular matrix-bound tumor necrosis factor-alpha.
Differential expression of matrix metalloproteinases and their inhibitors in non-small cell lung cancer.
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.
Differential inhibition of gelatinase activity in human colon adenocarcinoma cells by Aloe vera and Aloe arborescens extracts.
DIFFERENTIAL INHIBITION OF TUMOUR CELL-INDUCED PLATELET AGGREGATION BY NICOTINATE ASPIRIN PRODRUG (ST0702) AND ASPIRIN.
Differential regulation of matrix metalloproteinases in human cancer cells by exogenous factors.
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice.
Differential roles of matrix metalloproteinase-9 and -2, depending on proliferation or differentiation of retinoblastoma cells.
Diffuse malignant mesothelioma of the peritoneum: a clinicopathological study of 35 patients treated locoregionally at a single institution.
Dihomo-?-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA.
Dimethyloxalylglycine, a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3D spheroids.
Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours.
Direct cell-cell interaction enhances pro-MMP-2 production and activation in co-culture of laryngeal cancer cells and fibroblasts: involvement of EMMPRIN and MT1-MMP.
Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.
Discovery of selective hydroxamic acid inhibitors of tumor necrosis factor-alpha converting enzyme.
Disrupted Balance of MMPs/TIMPs in Gastric Carcinogenesis-Paradoxical Low MMP-2 Expression in Tumor and Stromal Compartments as a Potential Marker of Unfavorable Outcome.
Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity.
Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo.
Disseminated tumor cells in bone marrow of gastric cancer patients: correlation with tumor hypoxia and clinical relevance.
Distinct endobronchial expression of matrix-metalloproteinases (MMP) and their endogenous inhibitors in lung cancer.
Distinct Functionality of Tumor Cell-Derived Gelatinases during Formation of Liver Metastases.
Distinct patterns of matrix metalloproteinase-2 and -9 expression in normal human cell lines.
Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion.
Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression.
Diverse role of MMP-2 and MMP-9 in the clinicopathological behavior of Hodgkin's lymphoma.
Do Young Patients with Colorectal Cancer Have a Poorer Prognosis than Old Patients?
Dominant-negative transcription factor AP-2 augments SB-2 melanoma tumor growth in vivo.
Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer.
Down-Regulation of MT1-MMP expression by the alpha3 chain of type IV collagen inhibits bronchial tumor cell line invasion.
Down-regulation of tumour gelatinase/inhibitor balance and preservation of tumour endothelium by an anti-metastatic ruthenium complex.
Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: effect on in vivo mammary tumor growth and angiogenesis.
Downregulation of cancer stem cell properties via mTOR signaling pathway inhibition by rapamycin in nasopharyngeal carcinoma.
Downregulation of Dicer enhances tumor cell proliferation and invasion.
Downregulation of FOXP3 inhibits invasion and immune escape in cholangiocarcinoma.
Downregulation of G3BPs inhibits the growth, migration and invasion of human lung carcinoma H1299 cells by suppressing the Src/FAK-associated signaling pathway.
Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model.
Downregulation of microRNA-1246 inhibits tumor growth and promotes apoptosis of cervical cancer cells by targeting thrombospondin-2.
Downregulation of PART1 Inhibits Proliferation and Differentiation of Hep3B Cells by Targeting hsa-miR-3529-3p/FOXC2 Axis.
Downregulation of reversion-inducing cysteine-rich protein with Kazal motifs in malignant melanoma: inverse correlation with membrane-type 1-matrix metalloproteinase and tissue inhibitor of metalloproteinase 2.
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness.
Doxorubicin and Trifolium pratense L. (Red clover) extract synergistically inhibits brain and lung metastases in 4T1 tumor-bearing BALB/c mice.
Doxycycline influences microcirculation patterns in b16 melanoma.
Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.
Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion.
Dual targeting of integrin ?v?3 and matrix metalloproteinase-2 for optical imaging of tumors and chemotherapeutic delivery.
Dual-drug nanomedicine with hydrophilic F127-modified magnetic nanocarriers assembled in amphiphilic gelatin for enhanced penetration and drug delivery in deep tumor tissue.
Dual-Responsive Size-Shrinking Nanocluster with Hierarchical Disassembly Capability for Improved Tumor Penetration and Therapeutic Efficacy.
Dual-Sensitive PEG-Sheddable Nanodrug Hierarchically Incorporating PD-L1 Antibody and Zinc Phthalocyanine for Improved Immuno-Photodynamic Therapy.
Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy.
Dulaglutide Alleviates LPS-Induced Injury in Cardiomyocytes.
Dulcitol suppresses proliferation and migration of hepatocellular carcinoma via regulating SIRT1/p53 pathway.
Dysregulation of anti-tumor immunity by the matrix metalloproteinase-2.
E-cadherin, MMP-2, and MMP-9 as prognostic markers in penile cancer: Analysis of 125 patients.
Early acquisition of gelatinolytic activity in carcinogenesis of the uterine cervix.
Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling.
Early effects of laparotomy and laparoscopy on bacterial behavior and proinflammatory cytokines on bacterial peritonitis in rats I: Escherichia coli.
Early laminar events involving endothelial activation in horses with black walnut- induced laminitis.
Edaravone, a novel antidote against lung injury and pulmonary fibrosis induced by paraquat?
Efects of pdt with 5-aminolevulinic acid and chitosan on walker carcinosarcoma.
Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.
Effect of arginine on angiogenesis induced by human colon cancer: in vitro and in vivo studies.
Effect of AT2 blockade on cardiac hypertrophy as induced by high dietary salt in the proatrial natriuretic peptide (ANP) gene-disrupted mouse.
Effect of c-myc, Ki-67, MMP-2 and VEGF expression on prognosis of hepatocellular carcinoma patients undergoing tumor resection.
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Effect of combined cyclooxygenase-2 and matrix metalloproteinase inhibition on human sarcoma xenografts.
Effect of Conjugated Linoleic Acid Supplementation on Inflammatory Factors and Matrix Metalloproteinase Enzymes in Rectal Cancer Patients Undergoing Chemoradiotherapy.
Effect of doxycycline on proliferation, MMP production, and adhesion in LAM-related cells.
Effect of Etiasa on the expression of matrix metalloproteinase-2 and tumor necrosis factor-? in a rat model of ulcerative colitis.
Effect of hGC-MSCs from human gastric cancer tissue on cell proliferation, invasion and epithelial-mesenchymal transition in tumor tissue of gastric cancer tumor-bearing mice.
Effect of isofebrifugine on the proliferation and invasion of human gastric cancer cells via MMP.
Effect of matrix metalloproteinase inhibitors on tumor growth and spontaneous metastasis.
Effect of metallothioneins on transformation of gelatinase A from human fibroblast WI-38 cells.
Effect of Sirtuin 1 inhibition on matrix metalloproteinase 2 and Forkhead box O3a expression in breast cancer cells.
Effect of thalidomide on cardiac remodeling in chronic heart failure: results of a double-blind, placebo-controlled study.
Effect of troglitazone on tumor growth and pulmonary metastasis development of the mouse osteosarcoma cell line LM8.
Effects of 17beta-estradiol on the expression of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-2 in human osteoblastic MG-63 cell cultures.
Effects of 420-nm intense pulsed light in an acne animal model.
Effects of chondrocyte-derived extracellular matrix in a dry eye mouse model.
Effects of Coriandrum sativum on Migration and Invasion Abilities of Cancer Cells.
Effects of curcumin on the role of MMP-2 in endometrial cancer cell proliferation and invasion.
Effects of doxycycline on intestinal ischemia reperfusion injury induced by abdominal compartment syndrome in a rat model.
Effects of EGF and TGF-alpha on invasion and proteinase expression of uterine cervical adenocarcinoma OMC-4 cells.
Effects of Enzymatic Activation on the Distribution of Fluorescently Tagged MMP-2 Cleavable Peptides in Cancer Cells and Spheroids.
Effects of epidermal growth factor on invasiveness through the extracellular matrix in high- and low-metastatic clones of RCT sarcoma in vitro.
Effects of Galectin-1 on Biological Behavior in Cervical Cancer.
Effects of genistein and 2-methoxyestradiol on matrix metalloproteinases and their inhibitors secreted by Ehrlich ascites tumor cells.
Effects of matrix metalloproteinase inhibitor BB-94 on liver cancer growth and metastasis in a patient-like orthotopic model LCI-D20.
Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes.
Effects of rhaponticin on retinal oxidative stress and inflammation in diabetes through NRF2/HO-1/NF-?B signalling.
Effects of RNA silencing of matrix metalloproteinase-2 on the growth of esophageal carcinoma cells in vivo.
Effects of RNAi-mediated matrix metalloproteinase-2 gene silencing on the invasiveness and adhesion of esophageal carcinoma cells, KYSE150.
Effects of sex steroids and growth factors on invasive activity and 5'-deoxy-5-fluorouridine sensitivity in ovarian adenocarcinoma OMC-3 cells.
Effects of sex steroids and growth factors on migration and invasion of endometrial adenocarcinoma SNG-M cells in vitro.
Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation.
Effects of sulfasalazine and its metabolites on steady state messenger RNA concentrations for inflammatory cytokines, matrix metalloproteinases, and tissue inhibitors of metalloproteinase in rheumatoid synovial fibroblasts.
Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
Effects of the Tight Junction Protein CLDN6 on Cell Migration and Invasion in High-Grade Meningioma.
Effects of tumor necrosis factor-alpha and interferon-gamma on expressions of matrix metalloproteinase-2 and -9 in human bladder cancer cells.
Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with 90Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mouse Model of Refractory Pancreatic Cancer.
Efficacy of decitabine-loaded gelatinases-stimuli nanoparticles in overcoming cancer drug resistance is mediated via its enhanced demethylating activity to transcription factor AP-2 epsilon.
EGCG attenuates pro-inflammatory cytokines and chemokines production in LPS-stimulated L02 hepatocyte.
EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2.
Elevated activities of MMP-2 in the non-tumorous lung tissues of curatively resected stage I NSCLC patients are associated with tumor recurrence and a poor survival.
Elevated cell migration, invasion and tumorigenicity in human KB carcinoma cells transfected with COX-2 cDNA.
Elevated concentrations of serum matrix metalloproteinase-2 and -9 and their associations with circulating markers of cardiovascular diseases in chronic arsenic-exposed individuals.
Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and staging.
Elevated levels of angiostatin in effusions from patients with malignant disease.
Elevated levels of circulating plasma matrix metalloproteinase 9 in non-small cell lung cancer patients.
Elevated levels of Mr 92,000 type IV collagenase during tumor growth in vivo.
Elevated levels of serum and plasma metalloproteinases in patients with gastric cancer.
Elevated Serum and Cerebrospinal Fluid CD138 in Patients With Anti-N-Methyl-d-Aspartate Receptor Encephalitis.
Elevated serum levels of human matrix metalloproteinase-9 (MMP-9) during the induction of peripheral blood stem cell mobilization by granulocyte colony-stimulating factor (G-CSF).
Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells.
Emerging Roles of PAR-1 and PAFR in Melanoma Metastasis.
EMMPRIN contributes to the in vitro invasion of human salivary adenoid cystic carcinoma cells.
Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts.
EMMPRIN silencing inhibits proliferation and perineural invasion of human salivary adenoid cystic carcinoma cells in vitro and in vivo.
Emmprin, released as a microvesicle in epithelioid sarcoma, interacts with fibroblasts.
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
EMMPRIN-mediated MMP regulation in tumor and endothelial cells.
Enamel matrix derivative induces the expression of tissue inhibitor of matrix metalloproteinase-3 in human gingival fibroblasts via extracellular signal-regulated kinase.
Enantioselective Effects of o,p'-DDT on Cell Invasion and Adhesion of Breast Cancer Cells: Chirality in Cancer Development.
Endometrial tumor invasiveness is related to metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expressions.
Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice.
Endothelial derived vasoactive factors and leukocyte derived inflammatory mediators in subjects with asymptomatic atherosclerosis.
Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity.
Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training.
Engineered peptides with enzymatically cleavable domains for controlling the release of model protein drug from "soft" nanoparticles.
Enhanced cell surface expression of matrix metalloproteinases and their inhibitors, and tumor-induced host response in progression of human gastric carcinoma.
Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence.
Enhanced expression of tissue inhibitors of metalloproteinases in human colorectal tumors.
Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.
Enhanced metastatic dissemination to multiple organs by melanoma and lymphoma cells in timp-3-/- mice.
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas.
Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers.
Enhancement of membrane-type 1-matrix metalloproteinase (MT1-MMP) production and sequential activation of progelatinase A on human squamous carcinoma cells co-cultured with human dermal fibroblasts.
Enhancement of radiotherapy efficacy by docetaxel-loaded gelatinase-stimuli PEG-Pep-PCL nanoparticles in gastric cancer.
Enhancing Accumulation and Penetration of HPMA Copolymer-Doxorubicin Conjugates in 2D and 3D Prostate Cancer Cells via iRGD Conjugation with an MMP-2 Cleavable Spacer.
Enhancing cancer targeting and anticancer activity by a stimulus-sensitive multifunctional polymer-drug conjugate.
Enrichment of regulatory T cells in invasive breast tumor correlates with the upregulation of IL-17A expression and invasiveness of the tumor.
Enzymatic activation of cell-penetrating peptides in self-assembled nanostructures triggers fibre-to-micelle morphological transition.
EphA2 overexpression is associated with angiogenesis in ovarian cancer.
Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions.
Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.
Epidermal growth factor receptor-mediated regulation of matrix metalloproteinase-2 and matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Epigallocatechin-3-gallate ameliorates LPS-induced inflammation by inhibiting the phosphorylation of Akt and ERK signaling molecules in rat H9c2 cells.
Epigallocatechin-3-gallate inhibits doxorubicin-induced inflammation on human ovarian tissue.
Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats.
Epigenetic Control of the Invasion-promoting MT1-MMP/MMP-2/TIMP-2 Axis in Cancer Cells.
Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors.
Epigenetically induced changes in nuclear textural patterns and gelatinase expression in human fibrosarcoma cells.
Epithelial expression of extracellular matrix metalloproteinase inducer/CD147 and matrix metalloproteinase-2 in neoplasms and precursor lesions derived from cutaneous squamous cells: An immunohistochemical study.
Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer.
Equine sarcoid fibroblasts over-express matrix metalloproteinases and are invasive.
ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer.
Esophageal Cancer Development: Crucial Clues Arising from the Extracellular Matrix.
Estradiol and tamoxifen regulate endostatin generation via matrix metalloproteinase activity in breast cancer in vivo.
Estrogen attenuates tumour progression in hepatocellular carcinoma.
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Estrogen receptor subtype expression and regulation is altered in papillary thyroid cancer after menopause.
Estrogenic and antiestrogenic regulation of MMP-2 and MMP-13 mRNA in RUCA-I endometrial tumor cells in vitro and in vivo.
Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts.
Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-?B signaling.
Euodia pasteuriana Methanol Extract Exerts Anti-Inflammatory Effects by Targeting TAK1 in the AP-1 Signaling Pathway.
EVALUATING MMP-2 AND TGFß-RI EXPRESSION IN CIRCULATING TUMOR CELLS OF PANCREATIC CANCER PATIENTS AND THEIR CORRELATION WITH CLINICAL EVOLUTION.
Evaluation of a Sesquiterpene as Possible Drug Lead Against Gelatinases via Molecular Dynamics Simulations.
Evaluation of a triple-helical peptide with quenched FluorSophores for optical imaging of MMP-2 and MMP-9 proteolytic activity.
Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary.
Evaluation of basement membrane degradation during TNF-alpha-induced increase in epithelial permeability.
Evaluation of chemotherapy with nanosomal paclitaxel and gene therapy expressing apoptosis-inducing proteins in the management of spontaneous canine mammary neoplasm.
Evaluation of EMMPRIN and MMP-2 in the prognosis of primary cutaneous malignant melanoma.
Evaluation of hepatocellular carcinoma aggressiveness by a panel of extracellular matrix antigens.
Evaluation of HIV RNA and markers of immune activation as predictors of HIV-associated dementia.
Evaluation of invasiveness of astrocytoma using (1)H-magnetic resonance spectroscopy: correlation with expression of matrix metalloproteinase-2.
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity.
Evaluation of Matrix Metalloproteinase-2 (MMP-2) Activity with Film in situ Zymography for Improved Cytological Diagnosis of Breast Tumors.
Evaluation of matrix metalloproteinase-2 and -9 in the cerebrospinal fluid of dogs with intracranial tumors.
Evaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment.
Evaluation of MMP-2, MMP-9, TIMP-1, TIMP-2, NGAL and MMP-9/NGAL complex in urine and sera from patients with bladder cancer.
Evaluation of potential Stat3-regulated genes in human breast cancer.
Evaluation of Suppressive Effects of Tranilast on the Invasion/Metastasis Mechanism in a Murine Pancreatic Cancer Cell Line.
Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients.
Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer.
Evodiamine inhibits the migration and invasion of nasopharyngeal carcinoma cells in vitro via repressing MMP-2 expression.
Ex-FABP: a fatty acid binding lipocalin developmentally regulated in chicken endochondral bone formation and myogenesis.
Excessive inflammation portends complications: Wound cytokines and head and neck surgery outcomes.
Excretion of matrix metalloproteinases 2 and 9 in urine is associated with a high stage and grade of bladder carcinoma.
Exploring the action of RGDV-gemcitabine on tumor metastasis, tumor growth and possible action pathway.
Exploring the prevalence of skin tears and skin properties related to skin tears in elderly patients at a long-term medical facility in Japan.
Exposure of melanoma cells to dacarbazine results in enhanced tumor growth and metastasis in vivo.
Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study.
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression.
Expression and activation of proteases in co-cultures.
Expression and activity of matrix metalloproteinases-2 and -9 in serum, core needle biopsies and tissue specimens of prostate cancer patients.
Expression and activity of MMPS and their regulators in ovarian cancer.
Expression and clinical significance of HMGB1 in human liver cancer: Knockdown inhibits tumor growth and metastasis in vitro and in vivo.
Expression and distribution of MMPs and TIMPs in human uveal melanoma.
Expression and function of CXCL12/CXCR4/CXCR7 in thyroid cancer.
Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer.
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo.
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas.
Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas.
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Expression and serum levels of MMP-2 and MMP-9 during human melanoma progression.
Expression and significance of MMP2 and HIF-1? in hepatocellular carcinoma.
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma.
Expression of 72 kilodalton and 92 kilodalton type IV collagenase in malignant fibrous histiocytomas and dermatofibromas.
Expression of 72 kilodalton type IV collagenase (gelatinase A) in benign and malignant ovarian tumors.
Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma.
Expression of activated gelatinase in human invasive breast carcinoma.
Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors.
Expression of Alpha-Enolase (ENO1), Myc Promoter-Binding Protein-1 (MBP-1) and Matrix Metalloproteinases (MMP-2 and MMP-9) Reflect the Nature and Aggressiveness of Breast Tumors.
Expression of bcl-2 correlates with poor prognosis and modulates migration of nasopharyngeal carcinoma cells.
Expression of CD44 and MMP-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors.
Expression of CD44v3 splice variant is associated with the visceral metastatic phenotype of human melanoma.
Expression of collagenase IV (basement membrane collagenase) activity in murine tumor cell hybrids that differ in metastatic potential.
Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
Expression of COX-2 is increased with age in papillary thyroid cancer.
Expression of CXCR4 and MMP-2 is associated with poor prognosis in patients with osteosarcoma.
Expression of cyclooxygenase-2 in colorectal cancer and its clinical significance.
Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival.
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Expression of cytokeratin 19 and matrix metalloproteinase 2 predicts lymph node metastasis in hepatocellular carcinoma.
Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.
Expression of decorin in esophageal cancer in relation to the expression of three isoforms of transforming growth factor-beta (TGF-beta1, -beta2, and -beta3) and matrix metalloproteinase-2 activity.
Expression of Discoidin Domain Receptor 2 (DDR2) Extracellular Domain in Pichia Pastoris and Functional Analysis in Synovial Fibroblasts and NIT3T3 Cells.
Expression of E-cadherin, beta-catenin, cathepsin D, gelatinases and their inhibitors in invasive ductal breast carcinomas.
Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Expression of emmprin and matrix metalloproteinases (MMPs) in peripheral nerve sheath tumors: emmprin and membrane-type (MT)1-MMP expressions are associated with malignant potential.
Expression of EMMPRIN in adenoid cystic carcinoma of salivary glands: correlation with tumor progression and patients' prognosis.
Expression of extracellular matrix-degrading proteins in classic, atypical, and anaplastic meningiomas.
Expression of Fhit, cell adhesion molecules and matrix metalloproteinases in atypical adenomatous hyperplasia and pulmonary adenocarcinoma.
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Expression of gelatinase (MMP-2 and MMP-9) and cyclooxygenase-2 (COX-2) in endometrial carcinoma.
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Expression of gelatinase-A (MMP-2) in human colon cancer and normal colon mucosa.
Expression of gelatinase/type IV collagenase in tumor necrosis correlates with cell detachment and tumor invasion.
Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells.
Expression of genes in the canine pre-implantation uterus and embryo: implications for an active role of the embryo before and during invasion.
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Expression of hypoxia-inducible factor-1?, vascular endothelial growth factor and matrix metalloproteinase-2 in sacral chordomas.
Expression of immunoreactive matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human normal livers and primary liver tumors.
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis.
Expression of laminin, collagen IV, fibronectin, and type IV collagenase in gastric carcinoma. An immunohistochemical study of 87 patients.
Expression of latent matrix metalloproteinase 9 (MMP-9) predicts survival in advanced ovarian cancer.
Expression of LGR8 and related biomarkers in hepatocellular carcinoma: correlation with clinicopathological parameters.
Expression of matrix metalloprotease-2 (MMP-2) and the activator membrane type 1 (MT1-MMP) in canine mammary carcinomas.
Expression of matrix metalloprotease-9 in vascular pericytes in human breast cancer.
Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung.
Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck.
Expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in medullary thyroid carcinoma: prognostic implications.
Expression of matrix metalloproteinase 2 (MMP-2), E-cadherin and Ki-67 in metastatic and non-metastatic canine mammary carcinomas.
Expression of matrix metalloproteinase 2 and 9 in breast cancer and breast fibroadenoma: a randomized, double-blind study.
Expression of Matrix Metalloproteinase 2 and Extracellular Matrix Metalloproteinase Inducer are Unfavorable Postoperative Prognostic Factors in Intrahepatic Cholangiocarcinoma.
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Expression of matrix metalloproteinase 9 (MMP-9/gelatinase B) in adenocarcinomas strongly correlated with expression of immune response genes.
Expression of matrix metalloproteinase gelatinase A messenger ribonucleic acid in parathyroid carcinomas.
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Expression of matrix metalloproteinase-2 (MMP-2) and of membrane-type-1-matrix metalloproteinase (MT1-MMP) in transitional cell carcinoma of the upper urinary tract.
Expression of matrix metalloproteinase-2 (mmp-2) in cervical neoplasia - immunohistochemical and in-situ hybridization studies.
Expression of matrix metalloproteinase-2 and -9 and membrane-type 1 matrix metalloproteinase in melanocytic tumors of dogs and canine melanoma cell lines.
Expression of matrix metalloproteinase-2 and -9 and their inhibitors, tissue inhibitor of metalloproteinase-1 and -2, in primary cultures of human prostatic stromal and epithelial cells.
Expression of matrix metalloproteinase-2 and -9 during early human wound healing.
Expression of matrix metalloproteinase-2 and -9 in human ligamentum flavum cells treated with tumor necrosis factor-? and interleukin-1?.
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Expression of matrix metalloproteinase-2 and survivin in endometrioid and nonendometrioid endometrial cancers and clinicopathologic significance.
Expression of matrix metalloproteinase-2 in glial and neuronal tumor cell lines: inverse correlation with proliferation rate.
Expression of matrix metalloproteinase-2 in preinvasive and invasive carcinoma of the uterine cervix.
Expression of matrix metalloproteinase-2 in renal cell carcinoma.
Expression of matrix metalloproteinase-2 in serous borderline ovarian tumors is associated with noninvasive implant formation.
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Expression of Matrix Metalloproteinase-2, but not Caspase-3, Facilitates Distinction between Benign and Malignant Thyroid Follicular Neoplasms.
Expression of matrix metalloproteinases (MMP-2 and -9) and their inhibitors (TIMP-1 and -2) in prostate cancer tissue.
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Expression of matrix metalloproteinases (MMPs) in cultured hepatocellular carcinoma (HCC) cells and surgically resected HCC tissues.
Expression of matrix metalloproteinases (MMPs-2, -7, -9, and -26) and tissue inhibitors of metalloproteinases (TIMPs-1 and -2) in pleomorphic adenomas and adenoid cystic carcinomas.
Expression of matrix metalloproteinases 2 and 7 in tumor cells correlates with the World Health Organization classification subtype and clinical stage of thymic epithelial tumors.
Expression of matrix metalloproteinases 2 and 9 in human gastric cancer and superficial gastritis.
Expression of matrix metalloproteinases 2 and 9 in meningiomas associated with different degrees of brain invasiveness and edema.
Expression of matrix metalloproteinases 2, 7 and 9 in patients with colorectal cancer.
Expression of matrix metalloproteinases 7 and 2 in human renal cell carcinoma.
Expression of Matrix Metalloproteinases and Its Inhibitor in Gastric Adenocarcinoma.
Expression of matrix metalloproteinases and their inhibitors correlates with invasion and metastasis in squamous cell carcinoma of the head and neck.
Expression of matrix metalloproteinases and their inhibitors in human brain tumors.
Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: quantificative and morphological analyses.
Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance.
Expression of matrix metalloproteinases and their inhibitors in retinoblastoma.
Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in non-small-cell lung cancer.
Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in head and neck squamous cell carcinoma.
Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in laryngeal and pharyngeal squamous cell carcinoma: A quantitative analysis.
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in uterine endometrial carcinoma and a correlation between expression of matrix metalloproteinase-7 and prognosis.
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas.
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in reactive and neoplastic lymphoid cells.
Expression of matrix metalloproteinases in a series of 12 meningiomas.
Expression of matrix metalloproteinases in benign and malignant follicular thyroid lesions.
Expression of matrix metalloproteinases in gallbladder carcinoma and their significance in carcinogenesis.
Expression of matrix metalloproteinases in human transitional cell carcinoma of the urinary bladder.
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Expression of matrix metalloproteinases in supraglottic carcinoma and its clinical implication for estimating lymph node metastases.
Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation.
Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression.
Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1, -2, and -3 in benign and malignant tumours of the salivary gland.
Expression of matrix metalloproteinases, cytokines, and connexins in diabetic and nondiabetic human keratinocytes before and after transplantation into an ex vivo wound-healing model.
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Expression of matrix metalloproteinases, tissue inhibitors of metalloproteinase, collagens, and Ki67 antigen in pleural malignant mesothelioma: an immunohistochemical and electron microscopic study.
Expression of matrix metalloproteinases-1, -2, and -9; tissue inhibitors of matrix metalloproteinases-1 and -2; cathepsin B; urokinase plasminogen activator; and plasminogen activator inhibitor, type I in skull base chordoma.
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Expression of Matrix Metalloproteinases-2/-9 is Associated With Microvessel Density in Pancreatic Cancer.
Expression of membrane type 1 matrix metalloproteinase (MMP-14) in epithelial ovarian cancer: high level expression in clear cell carcinoma.
Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization.
Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma.
Expression of membrane-anchored matrix metalloproteinase inhibitor reversion inducing cysteine rich protein with Kazal motifs in murine cell lines.
Expression of membrane-type matrix metalloproteinase in rabbit neointimal tissue and its correlation with matrix-metalloproteinase-2 activation.
Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma.
Expression of metalloproteinase-2, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in transitional cell carcinoma of upper urinary tract: correlation with tumor stage and survival.
Expression of metalloproteinases (MMP-2 and MMP-9) in basal-cell carcinoma.
Expression of metalloproteinases and their inhibitors in adenocarcinoma of the uterine cervix.
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis.
Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysis.
Expression of metalloproteinases MMP-2 and MMP-9 in sentinel lymph node and serum of patients with metastatic and non-metastatic breast cancer.
Expression of metalloproteinases MMP-2 and MMP-9 is associated to the presence of androgen receptor in epithelial ovarian tumors.
Expression of MMP-2 and -9 in short-term cultures of meningioma: influence of histological subtype.
Expression of MMP-2 and MMP-9 in Benign Canine Rostrotentorial Meningiomas Is Not Correlated to the Extent of Peritumoral Edema.
Expression of MMP-2 and MMP-9 in retinoblastoma and their significance.
Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas.
Expression of MMP-2 and TIMP-3 with incidence and prognosis of giant-cell tumor of the bone.
Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma.
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Expression of MMP-2, MMP-9, and urokinase-type plasminogen activator in cervical intraepithelial neoplasia.
Expression of MMP-2,TIMP-2 protein and the ratio of MMP-2/TIMP-2 in gallbladder carcinoma and their significance.
Expression of MMP-7 and MT1-MMP in peritoneal dissemination of gastric cancer.
Expression of MMPs and TIMPs in human pterygia and cultured pterygium epithelial cells.
Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.
Expression of mRNA for gelatinase A and TIMP-2 in cell cultures and tissue samples derived from breast and lung carcinomas.
Expression of nm23, MMP-2, TIMP-2 in breast neoplasm in Zhengzhou Center Hospital, China.
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Expression of protease activated receptor-1 in chronic periodontitis.
Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells.
Expression of RECK and matrix metalloproteinase-2 in ameloblastoma.
Expression of RECK and MMP-2 in salivary adenoid cystic carcinoma: Correlation with tumor progression and patient prognosis.
Expression of the active form of MMP-2 on the surface of leukemic cells accounts for their in vitro invasion.
Expression of the extracellular matrix metalloproteinase inducer (EMMPRIN) and the matrix metalloproteinase-2 in bronchopulmonary and breast lesions.
Expression of the miR200 family of microRNAs in mesothelial cells suppresses the dissemination of ovarian cancer cells.
Expression of tissue inhibitor of matrix metalloproteinase-2 correlates with activation of matrix metalloproteinase-2 and predicts poor prognosis in tongue squamous cell carcinoma.
Expression of tissue inhibitor of metalloproteinase-1 and type IV collagenase/gelatinase messenger RNAs in human breast cancer.
Expression of tissue inhibitor of metalloproteinase-3 (TIMP-3) and its prognostic significance in resected non-small cell lung cancer.
Expression of tissue inhibitor of metalloproteinase-3 by transplanted VSMCs modifies heart structure and function after myocardial infarction.
Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage.
Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer.
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in renal cell carcinoma.
Expression of type IV collagen and its degrading enzymes in squamous cell carcinoma of lung.
Expression of type IV collagenase and procollagen genes and its correlation with the tumorigenic, invasive, and metastatic abilities of oncogene-transformed human bronchial epithelial cells.
Expression of type IV collagenase correlates with the expression of vascular endothelial growth factor in primary non-small cell lung cancer.
Expression of WTH3 in breast cancer tissue and the effects on the biological behavior of breast cancer cells.
Expression patterns of seprase, a membrane serine protease, in cervical carcinoma and cervical intraepithelial neoplasm.
Expression patterns of stromal MMP-2 and tumoural MMP-2 and -9 are significant prognostic factors in invasive ductal carcinoma of the breast.
Expression profile of epithelial-mesenchymal transition markers in non-muscle-invasive urothelial carcinoma of the bladder: correlation with intravesical recurrence following transurethral resection.
Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination.
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Expression, association with clinicopathological features and prognostic potential of CEP55, p-Akt, FoxM1 and MMP-2 in astrocytoma.
Expression, purification, refolding and in vitro recovery of active full length recombinant human gelatinase MMP-9 in Escherichia coli.
Expressions of CD147, MMP-2 and MMP-9 in Laryngeal Carcinoma and its Correlation with Poor Prognosis.
Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma.
Expressions of Matrix Metalloproteinases 2, 7, and 9 in Carcinogenesis of Pancreatic Ductal Adenocarcinoma.
Expressions of matrix metalloproteinases in early-stage oral squamous cell carcinoma as predictive indicators for tumor metastases and prognosis.
Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma.
Extracellular binding of indinavir to matrix metalloproteinase-2 and the alpha-7-nicotinic acetylcholine receptor: implications for use in cancer treatment.
Extracellular heat shock protein (Hsp)70 and Hsp90? assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion.
Extracellular Matrix Component Shelled Nanoparticles as Dual Enzyme-Responsive Drug Delivery Vehicles for Cancer Therapy.
Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung.
Extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 overexpression is associated with loss of hormone receptor expression and poor prognosis in endometrial cancer.
Extracellular Phosphorylation of TIMP-2 by Secreted c-Src Tyrosine Kinase Controls MMP-2 Activity.
Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas.
Extracellular roles for the molecular chaperone, hsp90.
Fabrication of In Vitro Cancer Microtissue Array on Fibroblast-Layered Nanofibrous Membrane by Inkjet Printing.
FAK signaling in neoplastic disorders: a linkage between inflammation and cancer.
Feline Injection-Site Sarcoma.
Fibroblast activation protein ? in tumor microenvironment: Recent progression and implications (Review).
Fibroblast Enhancement of Tumor Invasion in a Tumor-Host Interface Recapitulated in-vitro.
Fibroblast remodeling of adsorbed collagen type IV is altered in contact with cancer cells.
Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo.
Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells.
Fibrotic injury after experimental deep vein thrombosis is determined by the mechanism of thrombogenesis.
Fine Particulate Matter (PM2.5) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway.
Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angioprevention.
Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma.
Flubendazole elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.
Fluorogenic Disassembly of Self-Quenched Near-Infrared Nanoparticles Enables Matrix Metalloproteinase Detection.
Focal adhesion kinase activation is required for TNF-?-induced production of matrix metalloproteinase-2 and proinflammatory cytokines in cultured human periodontal ligament fibroblasts.
Focal localization of inflammatory cytokines and neurotrophins in a tongue chronic injury model.
Folate-decorated arginine-based poly(ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells.
FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness.
Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer.
Fragment-Based Discovery of 5-Arylisatin-Based Inhibitors of Matrix Metalloproteinases 2 and 13.
Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease.
Fully human anti-interleukin 8 antibody inhibits tumor growth in orthotopic bladder cancer xenografts via down-regulation of matrix metalloproteases and nuclear factor-kappaB.
Fully human antibodies to MCAM/MUC18 inhibit tumor growth and metastasis of human melanoma.
Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma.
Function of alpha3beta1-tetraspanin protein complexes in tumor cell invasion. Evidence for the role of the complexes in production of matrix metalloproteinase 2 (MMP-2).
Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase.
Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis.
Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis.
Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma.
Functional examination of novel kisspeptin phosphinic peptides.
Functional expression of the chemokine receptor XCR1 on oral epithelial cells.
Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.
Functional mimetic peptide discovery isolated by phage display interacts selectively to fibronectin domain and inhibits gelatinase.
Functional role of matrix metalloproteinases in ovarian tumor cell plasticity.
Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer.
Fusion expression of DDR2 extracellular domain in insect cells and its purification and function characterization.
Fuzheng Huayu Formula () prevents rat renal interstitial fibrosis induced by HgCl2 via antioxidative stress and down-regulation of nuclear factor-kappa B activity.
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Galectin-1-mediated tumor invasion and metastasis, up-regulated matrix metalloproteinase expression, and reorganized actin cytoskeletons.
Galloyl cyclic-imide derivative CH1104I inhibits tumor invasion through suppressing matrix metalloproteinase activity.
GALNT14 mediates tumor invasion and migration in breast cancer cell MCF-7.
Gamabufotalin suppressed osteosarcoma stem cells through the TGF-?/periostin/PI3K/AKT pathway.
Gamma Radiation-Attenuated Toxoplasma gondii Provokes Apoptosis in Ehrlich Ascites Carcinoma-Bearing Mice Generating Long-Lasting Immunity.
Gamma-irradiation induces matrix metalloproteinase II expression in a p53-dependent manner.
Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression.
Gelatin zymography and substrate cleavage assays of matrix metalloproteinase-2 in breast carcinoma cells overexpressing membrane type-1 matrix metalloproteinase.
Gelatin-degrading type IV collagenase isolated from human small cell lung cancer.
Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy.
Gelatinase A (MMP-2) and its mRNA detected in both neoplastic and stromal cells of tumors with different invasive and metastatic properties.
Gelatinase A activation is regulated by the organization of the polymerized actin cytoskeleton.
Gelatinase A and membrane-type 1 matrix metalloproteinase mRNA: expressed in adrenocortical cancers but not in adenomas.
Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy.
Gelatinase A, membrane type 1 matrix metalloproteinase, and extracellular matrix metalloproteinase inducer mRNA expression: correlation with invasive growth of breast cancer.
Gelatinase A-immunoreactive protein in ovarian lesions- prognostic value in epithelial ovarian cancer.
Gelatinase A/TIMP-2 imbalance in lymph-node-positive breast carcinomas, as measured by RT-PCR.
Gelatinase activity of matrix metalloproteinases during first-line chemotherapy in lung adenocarcinoma patients: an initial approach.
Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression.
Gelatinase concentrations and zymographic profiles in human breast cancer: matrix metalloproteinases circulating in plasma are better markers for the subclassification and early prediction of cancer: the coagulation/fibrinolysis pathways alter the release, activation and recovery of different gelatinases in serum.
Gelatinase expression in Retinoblastoma: Modulation of LHBETATAG retinal tumor development by Anecortave Acetate.
Gelatinase inhibitors: a patent review (2011-2017).
Gelatinase levels in male and female breast cancer.
Gelatinase secretion by glomerular epithelial cells.
Gelatinase-mediated migration and invasion of cancer cells.
Gelatinase-stimuli strategy enhances the tumor delivery and therapeutic efficacy of docetaxel-loaded poly(ethylene glycol)-poly(?-caprolactone) nanoparticles.
Gelatinases A and B (MMP-2 and MMP-9) in endometrial cancer-MMP-9 correlates to the grade and the stage.
Gelatinases and their inhibitors in tumor metastasis: from biological research to medical applications.
Gelatinases of murine metastatic tumor cells.
Gelatinolytic activities (matrix metalloproteinase-2 and -9) and soluble extracellular domain of Her-2/neu in pleural effusions.
Gelatinolytic activity of matrix metalloproteinase in tumor tissues correlates with the invasiveness of oral cancer.
Gelatinolytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9 in rat brain after implantation of 9L rat glioma cells.
Gene Expression of Matrix Metalloproteinases and their Inhibitors (TIMPs) in Meningiomas of Dogs.
Gene polymorphisms in odontogenic keratocysts and ameloblastomas: A systematic review.
General protease and collagenase (IV) activity in C6 astrocytoma cells, C6 spheroids and implanted C6 spheroids.
Generation and antitumor effects of an engineered and energized fusion protein VL-LDP-AE composed of single-domain antibody and lidamycin.
Generation of antitumor peptides by connection of matrix metalloproteinase-9 peptide inhibitor to an endostatin fragment.
Genes controlling spread of breast cancer to lung "gang of 4".
Genes of laminin B1 chain, alpha 1 (IV) chain of type IV collagen, and 72-kd type IV collagenase are mainly expressed by the stromal cells of lung carcinomas.
Genetic Deletion of Galectin-3 Alters the Temporal Evolution of Macrophage Infiltration and Healing Affecting the Cardiac Remodeling and Function after Myocardial Infarction in Mice.
Genetic Modification of Cell Lines to Enhance Their Metastatic Capability.
Genetic polymorphisms in the MMP-2 and MMP-9 genes and breast cancer phenotype.
Genetic Predisposition of Polymorphisms in HMGB1-Related Genes to Breast Cancer Prognosis in Korean Women.
Genetic susceptibility to progressive massive fibrosis in coal miners.
Genistein elicits pleiotropic molecular effects on head and neck cancer cells.
Genistein reinforces the inhibitory effect of Cisplatin on liver cancer recurrence and metastasis after curative hepatectomy.
Genistein-selenium combination induces growth arrest in prostate cancer cells.
GHGKHKNK Octapeptide (P-5m) Inhibits Metastasis of HCCLM3 Cell Lines via Regulation of MMP-2 Expression in in Vitro and in Vivo Studies.
GHRH antagonist inhibits focal adhesion kinase (FAK) and decreases expression of vascular endothelial growth factor (VEGF) in human lung cancer cells in vitro.
Ginseng intestinal bacterial metabolite IH901 as a new anti-metastatic agent.
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE?cadherin/EphA2/MMP9/MMP2 expression.
Glioma invasion in vitro: regulation by matrix metalloprotease-2 and protein kinase C.
Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model.
Gluten exacerbates atherosclerotic plaque formation in ApoE-/- mice with diet-induced obesity.
GM-CSF enhances tumor invasion by elevated MMP-2, -9, and -26 expression.
Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via beta-catenin signaling in ovarian cancer cells.
Granulocyte colony-stimulating factor (G-CSF)-mediated signaling regulates type IV collagenase activity in head and neck cancer cells.
Grape seed extract suppresses MDA-MB231 breast cancer cell migration and invasion.
Growth factor stimulation of matrix metalloproteinase expression and myoblast migration and invasion in vitro.
Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.
Growth pattern correlates with the distribution of basement membrane and prognosis in lung adenocarcinoma.
Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9.
Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2/ -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways.
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.
Halofuginone inhibits phosphorylation of SMAD-2 reducing angiogenesis and leukemia burden in an acute promyelocytic leukemia mouse model.
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition.
HDAC inhibitor trichostatin A suppresses esophageal squamous cell carcinoma metastasis through HADC2 reduced MMP-2/9.
Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression.
Heat shock-mediated transient increase in intracellular 3',5'-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation.
Heme oxygenase-1 expression is associated with tumor aggressiveness and outcomes in patients with bladder cancer: a correlation with smoking intensity.
Heme oxygenase-1 mediates protective effects on inflammatory, catabolic and senescence responses induced by interleukin-1? in osteoarthritic osteoblasts.
Hepatic ischemia/reperfusion injury is prevented by a novel matrix metalloproteinase inhibitor, ONO-4817.
Hepatoprotective effect of forsythiaside a against acetaminophen-induced liver injury in zebrafish: Coupling network pharmacology with biochemical pharmacology.
Herbal compound "Songyou Yin" reinforced the ability of interferon-alfa to inhibit the enhanced metastatic potential induced by palliative resection of hepatocellular carcinoma in nude mice.
Herbal extract "Songyou Yin" inhibits tumor growth and prolongs survival in nude mice bearing human hepatocellular carcinoma xenograft with high metastatic potential.
Hesperidin Prevents Nitric Oxide Deficiency-Induced Cardiovascular Remodeling in Rats via Suppressing TGF-?1 and MMPs Protein Expression.
Hierarchical virtual screening of the dual MMP-2/HDAC-6 inhibitors from natural products based on pharmacophore models and molecular docking.
HIF-1? contributes to hypoxia-induced invasion and metastasis of esophageal carcinoma via inhibiting E-cadherin and promoting MMP-2 expression.
HIF-2? as a prognostic marker for breast cancer progression and patient survival.
High expression levels of nuclear factor kappa B and gelatinases in the tumorigenesis of oral squamous cell carcinoma.
High Expression of MMP-9 in Primary Tumors and High Preoperative MPO in Serum Predict Improved Prognosis in Colorectal Cancer with Operable Liver Metastases.
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
High galectin-1 expression correlates with poor prognosis and is involved in epithelial ovarian cancer proliferation and invasion.
High Grade T1 Papillary Urothelial Bladder Cancer Shows Prominent Peritumoral Retraction Clefting.
High level of MT-MMP expression is associated with invasiveness of cervical cancer cells.
High levels of messenger RNAs for tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in primary breast carcinomas are associated with development of distant metastases.
High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma.
High levels of tissue inhibitor of metalloproteinase-1 predict poor outcome in patients with breast cancer.
High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer.
High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells.
High molecular weight hyaluronic acid down-regulates the gene expression of osteoarthritis-associated cytokines and enzymes in fibroblast-like synoviocytes from patients with early osteoarthritis.
High threshold of ?1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2).
High-grain diet feeding altered the composition and functions of the rumen bacterial community and caused the damage to the laminar tissues of goats.
High-protein diet associated with resistance training reduces cardiac TNF-? levels and up-regulates MMP-2 activity in rats.
High-throughput functional profiling of single adherent cells via hydrogel drop-screen.
High-yield clicking and dissociation of doxorubicin nanoclusters exhibiting differential cellular uptakes and imaging.
Highly expressed tumoral emmprin and stromal CD73 predict a poor prognosis for external auditory canal carcinoma.
Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer.
Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion.
Histone deacetylase inhibitor, apicidin, inhibits human ovarian cancer cell migration via class II histone deacetylase 4 silencing.
HIV protease inhibitors as new treatment options for Kaposi's sarcoma.
HIV-1 modulates the expression of gelatinase A and B in monocytic cells.
Homology cloning of rat 72 kDa type IV collagenase: cytokine and second-messenger inducibility in glomerular mesangial cells.
HOW EXPRESSIONS OF CLAUDIN-1 AND MMP-2 IN RETINOBLASTOMA CORRELATE WITH HISTOLOGICAL DIFFERENTIATION AND OPTIC NERVE INVASION.
Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.
Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.
Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts.
Human mesenchymal stem cells play a dual role on tumor cell growth in vitro and in vivo.
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity.
Humoral and cellular immunity induced by tumor cell vaccine based on the chicken xenogeneic homologous matrix metalloproteinase-2.
Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin ?(v)?(3) interaction.
Hydroxamate-based peptide inhibitors of matrix metalloprotease 2.
Hydroxysafflor yellow A suppresses angiogenesis of hepatocellular carcinoma through inhibition of p38 MAPK phosphorylation.
Hyperbaric oxygen activates discoidin domain receptor 2 via tumor necrosis factor-alpha and p38 pathway to increase vascular smooth muscle cells migration through matrix metalloproteinase 2.
Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse.
Hypoxia and proangiogenic proteins in human ameloblastoma.
Hypoxia influences vasculogenic mimicry channel formation and tumor invasion-related protein expression in melanoma.
Hypoxia level and matrix metalloproteinases-2 and -9 activity in Lewis lung carcinoma: correlation with metastasis.
Hypoxia suppresses E-cadherin and enhances matrix metalloproteinase-2 expression favoring esophageal carcinoma migration and invasion via hypoxia inducible factor-1 alpha activation.
Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma.
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Hypoxia-induced senescence contributes to the regulation of microenvironment in melanomas.
Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2.
IB05204, a dichloropyridodithienotriazine, inhibits angiogenesis in vitro and in vivo.
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors.
Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.
Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages.
Identification of matrix metalloproteinases in canine cutaneous mast cell tumors.
Identification of Non-Zinc Binding Inhibitors of MMP-2 Through Virtual Screening and Subsequent Rescoring.
Identification of novel, functional genetic variants in the human matrix metalloproteinase-2 gene: role of Sp1 in allele-specific transcriptional regulation.
Identification of patients with chronic obstructive pulmonary disease (COPD) by measurement of plasma biomarkers.
Identification of substrate sequences for membrane type-1 matrix metalloproteinase using bacteriophage peptide display library.
Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets.
IKK? Kinase Promotes Stemness, Migration, and Invasion in KRAS-Driven Lung Adenocarcinoma Cells.
IL-10 inhibits the NF-?B and ERK/MAPK-mediated production of pro-inflammatory mediators by up-regulation of SOCS-3 in Trypanosoma cruzi-infected cardiomyocytes.
IL-1?, IL-8, and Matrix Metalloproteinases-1, -2, and -10 Are Enriched upon Monocyte-Breast Cancer Cell Cocultivation in a Matrigel-Based Three-Dimensional System.
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Imbalance between serum matrix metalloproteinase-2 and its inhibitor as a predictor of recurrence of urothelial cancer.
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Imetelstat (a telomerase antagonist) exerts off?target effects on the cytoskeleton.
Immortalization of human aortic smooth muscle cells with origin-minus simian virus 40 DNA.
Immunization with a Mimotope of GD2 Ganglioside Induces CD8+ T Cells That Recognize Cell Adhesion Molecules on Tumor Cells.
Immunoassay of type IV collagenase/gelatinase (MMP-2) in human plasma.
Immunoassays of the metalloproteinase (MMP-2) and tissue inhibitor of metalloproteinase (TIMP 1 and 2) levels in noninvasive and metastatic PC-3 clones: effects of taxol.
Immunocharacterization of matrix metalloproteinase-2 and matrix metalloproteinase-9 in canine transmissible venereal tumors.
Immunocytochemical detection of matrix metalloproteinase expression in prostate cancer.
Immunocytochemical detection of the expression of members of the matrix metalloproteinase family in adenocarcinomas of the pancreas.
Immunoelectron microscopic localization of gelatinase A in human gastrointestinal and skin carcinomas: difference between cancer cells and fibroblasts.
Immunoexpression of matrix metalloproteinase-2 (MMP-2) in malignant ovarian epithelial tumours.
Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma.
Immunoexpression of Metalloproteinases 2 and 14 and TIMP-2 Inhibitor in Main Types of Primary Gastric Carcinomas and Lymph Node Metastasis.
Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
Immunogenicity moderation effect of interleukin-24 on myelogenous leukemia cells.
Immunohistochemical analysis of reactive astrocytes around glioblastoma: an immunohistochemical study of postmortem glioblastoma cases.
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage I and II endometrial cancer.
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage IB cervical cancer.
Immunohistochemical detection of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in ameloblastomas.
Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma.
Immunohistochemical detection of the 150-kDa oxygen-regulated protein in bladder cancer.
Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue.
Immunohistochemical evaluation of MMP-2 and TIMP-2 in canine mammary tumours: A survival study.
Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia.
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Immunohistochemical expression of matrix metalloproteinases in ameloblastomas and pericoronal follicles.
Immunohistochemical expression of MMP-2, MMP-9, and TIMP-2 in neuroblastoma: association with tumor progression and clinical outcome.
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Immunohistochemical Expression Profiles of Cell Adhesion Molecules, Matrix Metalloproteinases and their Tissue Inhibitors in Central and Peripheral Neoplastic Foci of Feline Mammary Carcinoma.
Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies.
Immunohistochemical studies of the expression of matrix metalloproteinase-2 and metalloproteinase-9 in human prostate cancer.
Immunohistochemical study of lung remodeling in mice exposed to cigarette smoke*.
Immunohistochemical study of membrane type-matrix metalloproteinases (MT-MMPs) and matrix metalloproteinase-2 (MMP-2) in dermatofibroma and malignant fibrous histiocytoma.
Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke.
Immunolocalization of matrix metallo-proteinases and their tissue inhibitor in human mammary pathology.
Immunolocalizations of human gelatinase (type IV collagenase, MMP-9) and TIMP (tissue inhibitor of metalloproteinases) in normal epidermis and some epidermal tumors.
Immunological characterization of cell-surface and soluble forms of membrane type 1 matrix metalloproteinase in human breast cancer cells and in fibroblasts.
Immunotherapy Using Oxygenated Water and Tumor-Derived Exosomes Potentiates Antitumor Immune Response and Attenuates Malignancy Tendency in Mice Model of Breast Cancer.
Impact and mechanism of non-steroidal anti-inflammatory drugs combined with chemotherapeutic drugs on human lung cancer-nude mouse transplanted tumors.
Impact of CD68/(CD3+CD20) ratio at the invasive front of primary tumors on distant metastasis development in breast cancer.
Impact of LIMK1, MMP2 and TNF-? variations for intracranial aneurysm in Japanese population.
Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage.
Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy.
Improving Tumor Specificity and Anticancer Activity of Dasatinib by Dual-Targeted Polymeric Micelles.
In situ injection of dual-delivery PEG based MMP-2 sensitive hydrogels for enhanced tumor penetration and chemo-immune combination therapy.
In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin.
In situ mRNA hybridization technique for analysis of metastasis-related genes in human colon carcinoma cells.
In vitro and ex vivo vanadium antitumor activity in (TGF-?)-induced EMT. Synergistic activity with carboplatin and correlation with tumor metastasis in cancer patients.
In vitro and in vivo antimetastatic effects of Terminalia catappa L. leaves on lung cancer cells.
In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3.
In vitro and in vivo investigation of matrix metalloproteinase expression in metastatic tumor models.
In vitro and in vivo matrix metalloproteinase expression after photodynamic therapy with a liposomal formulation of aminolevulinic acid and its methyl ester.
In vitro assessment of liposomal neridronate on MDA-MB-231 human breast cancer cells.
In vitro determination of basement membrane invasion predicts liver metastases in human gastrointestinal carcinoma.
In vitro effects of meloxicam on metabolism in articular chondrocytes from dogs with naturally occurring osteoarthritis.
In vitro expression of MMP-2 and MMP-9 in glioma cells following exposure to inflammatory mediators.
In vitro infection of macrophages by HIV: correlation with cellular activation, synthesis of tumour necrosis factor alpha and proteolytic activity.
In vitro inhibition of human MMP-2 collagenolytic and gelatinolytic activity by neutralizing monoclonal antibodies.
In vitro irradiation of basement membrane enhances the invasiveness of breast cancer cells.
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
In vitro modulation of the invasive and metastatic potentials of human renal cell carcinoma by interleukin-2 and/or interferon-alpha gene transfer.
In vitro modulation of tumor progression-associated properties of hormone refractory prostate carcinoma cell lines by cytokines.
In vitro ovarian cancer model based on three-dimensional agarose hydrogel.
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer.
In vivo effect of hyperbaric oxygen on wound angiogenesis and epithelialization.
In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture.
In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe.
In vivo imaging of tissue-remodeling activity involving infiltration of macrophages by a systemically administered protease-activatable probe in colon cancer tissues.
In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity.
In vivo self-assembly induced retention of gold nanoparticles for enhanced photothermal tumor treatment.
In-capillary screening of matrix metalloproteinase inhibitors by electrophoretically mediated microanalysis with fluorescence detection.
Increase in tissue inhibitor of metalloproteinase-2 (TIMP-2) levels and inhibition of MMP-2 activity in a metastatic breast cancer cell line by an anti-invasive small molecule SR13179.
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Increased expression of avian erythroblastosis virus E26 oncogene homolog 1 in World Health Organization grade 1 meningiomas is associated with an elevated risk of recurrence and is correlated with the expression of its target genes matrix metalloproteinase-2 and MMP-9.
Increased expression of gelatinase-a and timp-2 in primary human glioblastomas.
Increased expression of matrix metalloproteinase 7 and 9 and membrane type 1-matrix metalloproteinase in esophageal squamous cell carcinomas.
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Increased expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 is correlated with poor prognostic variables in patients with thymic epithelial tumors.
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Increased expression of matrix metalloproteinase-2 in the thickened intima of aged rats.
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Increased expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 with tumor dedifferentiation in hepatocellular carcinomas.
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Increased expression of seprase, a membrane-type serine protease, is associated with lymph node metastasis in human colorectal cancer.
Increased expression of the 72-kd type IV collagenase in prostatic adenocarcinoma. Demonstration by immunohistochemistry and in situ hybridization.
Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma.
Increased expression of tissue inhibitor of metalloproteinase-2 in clear cell carcinoma of the ovary.
Increased extracellular matrix remodeling is associated with tumor progression in human hepatocellular carcinomas.
Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.
Increased gelatinase-A and gelatinase-B activities in malignant vs. benign breast tumors.
Increased in situ gelatinolytic activity in renal cell tumor tissues correlates with tumor size, grade and vessel invasion.
Increased incidence of matrix metalloproteinases in urine of cancer patients.
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone.
Increased matrix metalloproteinase 2 concentration and transcript expression in advanced colorectal carcinomas.
Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma.
Increased matrix metalloproteinase-2 expression and reduced tissue factor pathway inhibitor-2 expression correlate with angiogenesis and early postoperative recurrence of pancreatic carcinoma.
Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells.
Increased matrix metalloproteinases 2 and 9 and tissue inhibitor of matrix metalloproteinase 2 expression is associated with progression from vulvar intraepithelial neoplasia to invasive carcinoma.
Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer.
Increased serum 72 KDa metalloproteinase in serous ovarian tumors: comparison with CA 125.
Increased serum type IV collagen 7-S levels in patients with hepatic metastasis.
Increased Twist and ZEB2 expression in a cutaneous metastasis of high-grade glioma.
Increased type IV collagenase in lgl-induced invasive tumors of Drosophila.
Induction and stimulation of 92-kDa gelatinase/type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor alpha.
Induction of cancer cell-specific death via MMP2 promoterdependent Bax expression.
Induction of fibroblast 92 kDa gelatinase/type IV collagenase expression by direct contact with metastatic tumor cells.
Induction of M(r) 92,000 type IV collagenase expression in a squamous cell carcinoma cell line by fibroblasts.
Induction of matrix metalloproteinase MMP-9 (92-kDa gelatinase) by retinoic acid in human neuroblastoma SKNBE cells: relevance to neuronal differentiation.
Induction of membrane-type matrix metalloproteinase-1 stimulates angiogenic activities of bovine aortic endothelial cells.
Induction of p53 without increase in p21WAF1 in betulinic acid-mediated cell death is preferential for human metastatic melanoma.
Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
Induction of vasculogenic mimicry overrides VEGF-A silencing and enriches stem-like cancer cells in melanoma.
Infiltration of blood outgrowth endothelial cells into tumor spheroids: role of matrix metalloproteinases and irradiation.
Infiltration of F98 glioma cells in Fischer rat brain is temporary stimulated by radiation.
Inflammatory biomarkers, vascular procedures of lower limbs, and wound healing.
Inflammatory cytokine modulation of matrix metalloproteinase expression and invasiveness of glioma cells in a 3-dimensional collagen matrix.
Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture.
Inflammatory cytokines and matrix metalloproteinases in the synovial fluid after intra-articular elbow fracture.
Inflammatory mechanisms contributing to pancreatic cancer development.
Influence of hydrogencalcium salts of oxidized cellulose on MMP-2, MMP-9 and TNF-? production and wound healing in non-healing wounds.
Influence of microenvironments on microcirculation patterns and tumor invasion-related protein expression in melanoma.
Influence of MMP-2 and MMP-9 promoter polymorphisms on gene expression and clinical outcome of non-small cell lung cancer.
Influence of New Synthetic Xanthones on the Proliferation and Migration Potential of Cancer Cell Lines in Vitro.
Influence of oleic acid on the expression, activation and activity of gelatinase A produced by oncogene-transformed human bronchial epithelial cells.
Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells.
Influence of the host microenvironment on the clonal selection of human colon carcinoma cells during primary tumor growth and metastasis.
Infrequent stromal expression of gelatinase A and intact basement membrane in intraductal neoplasms of the pancreas.
Inhibition activity of sulfated polysaccharide of Sepiella maindroni ink on matrix metalloproteinase (MMP)-2.
Inhibition by galloylglucose (GG6-10) of tumor invasion through extracellular matrix and gelatinase-mediated degradation of type IV collagens by metastatic tumor cells.
Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells.
Inhibition of AIDS-Kaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: implications for an anti-angiogenic therapy.
Inhibition of angiogenesis by anthracyclines and titanocene dichloride.
Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression.
Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.
Inhibition of Breast Cancer Metastasis by Presurgical Treatment with an Oral Matrix Metalloproteinase Inhibitor: A Preclinical Proof-of-Principle Study.
Inhibition of Caco-2 colon, MCF-7 and Hs578T breast, and DU 145 prostatic cancer cell proliferation by water-soluble black bean condensed tannins.
Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion.
Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells.
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins.
Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation.
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma.
Inhibition of Histone Deacetylase Attenuates Hypoxia-Induced Migration and Invasion of Cancer Cells via the Restoration of RECK Expression.
Inhibition of human glioma U251 cells growth in vitro and in vivo by hydroxyapatite nanoparticle-assisted delivery of short hairpin RNAs against SATB1.
Inhibition of human lung cancer cells by anti-p21Ras scFv mediated by the activatable cell-penetrating peptide.
Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine.
Inhibition of matrix metalloproteinase 2 maturation and HT1080 invasiveness by a synthetic furin inhibitor.
Inhibition of matrix metalloproteinase-14 in osteosarcoma cells by clodronate.
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone.
Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines.
Inhibition of mesothelioma cell growth in vitro by doxycycline.
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid.
Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma.
Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.
Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.
Inhibition of SPHK1 suppresses phorbol 12-myristate 13-acetate-induced metastatic phenotype in colorectal cancer HT-29 cells.
Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion.
Inhibition of tumor angiogenesis by Brahma Rasayana (BR).
Inhibition of tumor angiogenesis by cannabinoids.
Inhibition of tumor cell invasion by verapamil.
Inhibition of Tumor Growth and Metastasis by Non-Small Cell Lung Cancer Cells Transfected with Cyclin D1-Targeted siRNA.
Inhibition of tumor growth by ?-elemene through downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9 in a murine intraocular melanoma model.
Inhibition of tumor growth by quercetin with increase of survival and prevention of cachexia in Walker 256 tumor-bearing rats.
Inhibition of tumor-cell invasion with chlorotoxin-bound superparamagnetic nanoparticles.
Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells.
Inhibitory effect of acetylsalicylic acid on metalloproteinase activity in human lung adenocarcinoma at different stages of differentiation.
Inhibitory effect of aminoethyl-chitooligosaccharides on invasion of human fibrosarcoma cells.
Inhibitory effect of chitooligosaccharides on matrix metalloproteinase-9 in human fibrosarcoma cells (HT1080).
Inhibitory effect of Cho-Deung-San on human aortic smooth muscle cell migration induced by TNF-alpha through inhibition of matrix metalloproteinase-2 and -9 activity.
Inhibitory effect of green tea polyphenols on membrane-type 1 matrix metalloproteinase, MT1-MMP.
Inhibitory effect of isomorellin on cholangiocarcinoma cells via suppression of NF-?B translocation, the phosphorylated p38 MAPK pathway and MMP-2 and uPA expression.
Inhibitory effect of norcantharidin on melanoma tumor growth and vasculogenic mimicry by suppressing MMP-2 expression.
Inhibitory effect of siRNA-Annexin A7 on growth, migration, and invasion in BGC823 cells and gastric cancer xenograftsin nude mice.
Inhibitory effects of a nutrient mixture on human testicular cancer cell line NT 2/DT matrigel invasion and MMP activity.
Inhibitory Effects of a Reengineered Anthrax Toxin on Canine Oral Mucosal Melanomas.
Inhibitory effects of caffeic acid phenethyl ester on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
Inhibitory effects of Chanling Gao on the proliferation and liver metastasis of transplanted colorectal cancer in nude mice.
Inhibitory Effects of Dried Longan (Euphoria longana Lam.) Seed Extract on Invasion and Matrix Metalloproteinases of Colon Cancer Cells.
Inhibitory Effects of Ganoderma lucidum on Tumorigenesis and Metastasis of Human Hepatoma Cells in Cells and Animal Models.
Inhibitory effects of GL-V9 on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-2/9.
Inhibitory effects of polysaccharide extract from Spirulina platensis on corneal neovascularization.
Inhibitory effects of ubenimex (bestatin) on the invasion of uterine cervical carcinoma cells and their production and activation of gelatinase A.
Inhibitory effects on chondrosarcoma cell metastasis by Senna alata extract.
Inorganic sulfur reduces the motility and invasion of MDA-MB-231 human breast cancer cells.
Insight into the structural requirement of aryl sulphonamide based gelatinases (MMP-2 and MMP-9) inhibitors - Part I: 2D-QSAR, 3D-QSAR topomer CoMFA and Naïve Bayes studies - First report of 3D-QSAR Topomer CoMFA analysis for MMP-9 inhibitors and jointly inhibitors of gelatinases together.
Insulin like growth factor-1 selectively regulates the expression of matrix metalloproteinase-2 in malignant H-ras transformed cells.
Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes.
Integrating macrophages into organotypic co-cultures: a 3D in vitro model to study tumor-associated macrophages.
Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions.
Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
Integrin-mediated active tumor targeting and tumor microenvironment response dendrimer-gelatin nanoparticles for drug delivery and tumor treatment.
Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature.
Interaction between angiotensin II and relaxin 2 in the progress of growth and spread of prostate cancer cells.
Interaction of cocultured decidual endothelial cells and cytotrophoblasts in preeclampsia.
Interleukin 10 (IL-10) inhibition of primary human prostate cell-induced angiogenesis: IL-10 stimulation of tissue inhibitor of metalloproteinase-1 and inhibition of matrix metalloproteinase (MMP)-2/MMP-9 secretion.
Interleukin 10 blocks matrix metalloproteinase-2 and membrane type 1-matrix metalloproteinase synthesis in primary human prostate tumor lines.
Interleukin-1 and tumor necrosis factor-alpha induce collagenolysis and bone resorption by regulation of matrix metalloproteinase-2 in mouse calvarial bone cells.
Interleukin-1 beta induces differential gene expression in aortic smooth muscle cells.
Interleukin-10 induced activating transcription factor 3 transcriptional suppression of matrix metalloproteinase-2 gene expression in human prostate CPTX-1532 Cells.
Interleukin-6 expression by interactions between gynecologic cancer cells and human mesenchymal stem cells promotes epithelial-mesenchymal transition.
Interleukin-8 and Interleukin-17 for Cancer.
Interpretation of immunohistochemistry data of tumor should consider microenvironmental factors.
Interpreting gelatinase activity in tumor tissue and serum as a prognostic marker of naturally developing canine tumors.
Intracellular activation of gelatinase A (72-kDa type IV collagenase) by normal fibroblasts.
Intracellular expression of a single-chain antibody directed against type IV collagenase inhibits the growth of lung cancer xenografts in nude mice.
Intracellular localization of matrix metalloproteinases and their inhibitors in cultured tumor cell lines: flow cytometric analysis.
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Intratumoral macrophage counts correlate with tumor progression in colorectal cancer.
Invasion and metastases in gastric cancer: in vitro and in vivo models with clinical correlations.
Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung.
Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases.
Invasiveness and MMP expression in pancreatic carcinoma.
Investigating the Cellular Specificity in Tumors of a Surface-Converting Nanoparticle by Multimodal Imaging.
Investigation of a MMP-2 activity-dependent anchoring probe for nuclear imaging of cancer.
Investigation of MMP-2 and -9 in a highly invasive A431 tumor cell sub-line selected from a Boyden chamber assay.
Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma.
Investigation of vasculogenic mimicry in intracranial hemangiopericytoma.
Investigation of vasculogenic mimicry in sebaceous carcinoma of the eyelid.
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Involvement of matrix metalloproteinase activity in hormone-induced mammary tumor regression.
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Involvement of MMP-2 in adriamycin resistance dependent on ERK1/2 signal pathway in human osteosarcoma MG-63 cells.
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9.
Involvement of plasmin-mediated extracellular activation of progalanin in angiogenesis.
Involvement of STAT5 in Oncogenesis.
Ionizing radiation-inducible miR-494 promotes glioma cell invasion through EGFR stabilization by targeting p190B RhoGAP.
Irradiation of normal mouse tissue increases the invasiveness of mammary cancer cells.
Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1.
Isolation and characterization of human monoclonal antibodies specific to MMP-1A, MMP-2 and MMP-3.
Isolation and characterization of novel RECK tumor suppressor gene splice variants.
Ito cell morphology, alpha-smooth muscle actin and collagen type IV expression in the liver of patients with gastric and colorectal tumors.
JAK2/STAT3 pathway mediating inflammatory responses in heatstroke-induced rats.
JunB promotes cell invasion and angiogenesis in VHL-defective renal cell carcinoma.
JWA suppresses tumor angiogenesis via Sp1-activated MMP-2 and its prognostic significance in human gastric cancer.
KAI1 is a potential target for anti-metastasis in pancreatic cancer cells.
Ketoprofen in topical formulation decreases the matrix metalloproteinase-2 expression and pulmonary metastatic incidence in nude mice with osteosarcoma.
KI-67 AND hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma.
Kisspeptin?13 inhibits bleomycin?induced pulmonary fibrosis through GPR54 in mice.
Knockdown of PTTG1 inhibits the growth and invasion of lung adenocarcinoma cells through regulation of TGFB1/SMAD3 signaling.
Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells.
Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: characterization and expression in cultured cells.
l-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.
LABAZ1: A metastatic tumor model for renal cell carcinoma expressing the carbonic anhydrase type 9 tumor antigen.
Label-free colorimetric detection of gelatinases on nanoporous silicon photonic films.
Laminin receptors, collagenase IV and prognosis in node-negative breast cancers.
Laminin-5 gamma 2 chain and matrix metalloproteinase-2 may trigger colorectal carcinoma invasiveness through formation of budding tumor cells.
Laminin-5 gamma2 chain and matrix metalloproteinase-2 expression in the neoplastic changes of uterine cervical squamous epithelium.
Laminin-alpha1-chain sequence Leu-Gln-Val-Gln-Leu-Ser-Ile-Arg (LQVQLSIR) enhances murine melanoma cell metastases.
Largazole, a class I histone deacetylase inhibitor, enhances TNF-?-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts.
Lefty peptides, derived by MMP2 cleavage, act as a new class of gelatinase A inhibitor.
Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers.
Leptomycin B reduces matrix metalloproteinase-9 expression and suppresses cutaneous inflammation.
Levels of angiogenesis and expression of angiogenesis-related genes are prognostic for organ-specific metastasis of renal cell carcinoma.
Levels of Circulating TIMP-2 and MMP2-TIMP2 Complex Are Decreased in Squamous Cervical Carcinoma.
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.
Liarozole and 13-cis-retinoic acid anti-prostatic tumor activity.
Licochalcone A attenuates abdominal aortic aneurysm induced by angiotensin II via regulating the miR-181b/SIRT1/HO-1 signaling.
Limited processing of pro-matrix metalloprotease-2 (gelatinase A) overexpressed by transfection in PC-3 human prostate tumor cells: association with restricted cell surface localization of membrane-type matrix metalloproteinase-1.
Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer.
Lipid-soluble ginseng extract inhibits invasion and metastasis of B16F10 melanoma cells.
Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion.
Liposome-encapsulated hemoglobin enhances chemotherapy to suppress metastasis in mice.
Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.
LncRNA GAS6 antisense RNA 1 facilitates the tumorigenesis of clear cell renal cell carcinoma by regulating the AMP-activated protein kinase/mTOR signaling pathway.
Local antimicrobial, protease and cytokine defense systems in psoriatic skin.
Local cytokines induce differential expression of matrix metalloproteinases but not their tissue inhibitors in human endometrial fibroblasts.
Localization and quantification of mRNA for matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in human benign and malignant prostatic tissue.
Localization of messenger RNA for tissue inhibitor of metalloproteinases-1 and type IV collagenases/gelatinases in monkey hepatocellular carcinomas.
Localization of the 92 kd gelatinase mRNA in squamous cell and adenocarcinomas of the lung using in situ hybridization.
Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response?
Location of 72-kd metalloproteinase (type IV collagenase) in untreated prostatic adenocarcinoma.
Long Noncoding RNA HOTAIR Contributes to Progression in Hepatocellular Carcinoma by Sponging miR-217-5p.
Loss of Inhibitor of Growth (ING-4) Is Implicated in the Pathogenesis and Progression of Human Astrocytomas.
Loss of Suppressors of Cytokine Signaling 3 Promotes Aggressiveness in Hepatocellular Carcinoma.
Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism.
Low expression of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) indicates a shorter survival after resection in patients with adenocarcinoma of the lung.
Low serum level of pro-matrix metalloproteinase 2 correlates with aggressive behavior in breast carcinoma.
Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
LOX inhibition downregulates MMP-2 and MMP-9 in gastric cancer tissues and cells.
Luteolin inhibits IL-1?-induced in?ammation in rat chondrocytes and attenuates osteoarthritis progression in a rat model.
Luteolin inhibits the proliferation, adhesion, migration and invasion of choroidal melanoma cells in vitro.
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Lymphovascular invasion is associated with poor survival in gastric cancer: an application of gene-expression and tissue array techniques.
Macrophage interactions with collecting duct epithelial cells are capable of driving tubulointerstitial inflammation and fibrosis in immunoglobulin A nephropathy.
Macrophages Polarized by Expression of ToxoGRA15II Inhibit Growth of Hepatic Carcinoma.
Magnetic Semiconductor Gd-Doping CuS Nanoparticles as Activatable Nanoprobes for Bimodal Imaging and Targeted Photothermal Therapy of Gastric Tumors.
Magnolol suppresses the proliferation and invasion of cholangiocarcinoma cells via inhibiting the NF-?B signaling pathway.
Major co-localization of the extracellular-matrix degradative enzymes heparanase and gelatinase in tertiary granules of human neutrophils.
Malignancy of bladder cancer cells is enhanced by tumor-associated fibroblasts through a multifaceted cytokine-chemokine loop.
Malignant Fibrous Histiocytoma, Aggressive Fibromatosis and Benign Fibrous Tumors Express mRNA for the Metalloproteinase Inducer EMMPRIN and the Metalloproteinases MMP-2 and MT1-MMP.
Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma.
Manipulation of TAMs functions to facilitate the immune therapy effects of immune checkpoint antibodies.
Marchantin C: a potential anti-invasion agent in glioma cells.
Marked acceleration of the metastatic phenotype of a rat bladder carcinoma cell line by the expression of human gelatinase A.
Marked induction of gelatinases, especially type B, in host fibroblasts by human ovarian cancer cells in athymic mice.
Markers of immune activation and viral load in HIV-associated sensory neuropathy.
Mastic oil inhibits the metastatic phenotype of mouse lung adenocarcinoma cells.
Maternal infection with Schistosoma japonicum induces a profibrotic response in neonates.
Mathematical modeling of cancer invasion: the role of membrane-bound matrix metalloproteinases.
Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase.
Matrilysin expression in human prostate carcinoma.
Matrilysin-1 (MMP-7) and MMP-19 are expressed by Paget's cells in extramammary Paget's disease.
Matrix Metalloprotease 2-Responsive Multifunctional Liposomal Nanocarrier for Enhanced Tumor Targeting.
Matrix metalloproteinase (MMP) inhibition selectively decreases type II MMP activity in a murine model of pancreatic cancer.
Matrix metalloproteinase (MMP-2 and MMP-9) and steroid receptor expressions in feline mammary tumors.
Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes.
Matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor 2 (TIMP-2) in pancreatic cancer (PC).
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis.
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in the diagnosis of colorectal adenoma and cancer patients.
Matrix metalloproteinase 2 contributes to aggressive phenotype, epithelial-mesenchymal transition and poor outcome in nasopharyngeal carcinoma.
Matrix metalloproteinase 2 immunoreactive protein appears early in cervical epithelial dedifferentiation.
Matrix metalloproteinase 2 in tumor cell-induced platelet aggregation: regulation by nitric oxide.
Matrix metalloproteinase 2-responsive micelle for siRNA delivery.
Matrix metalloproteinase 9 expression is induced by Epstein-Barr virus latent membrane protein 1 C-terminal activation regions 1 and 2.
Matrix metalloproteinase activity in tumor, stromal tissue, and serum from cats with malignancies.
Matrix metalloproteinase and its drug targets therapy in solid and hematological malignancies: An overview.
Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis.
Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients.
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma.
Matrix metalloproteinase inhibition improves survival in an orthotopic model of human pancreatic cancer.
Matrix metalloproteinase inhibitor COL-3 in the treatment of AIDS-related Kaposi's sarcoma: a phase I AIDS malignancy consortium study.
Matrix metalloproteinase inhibitor MMI-166 inhibits lymphogenous metastasis in an orthotopically implanted model of lung cancer.
Matrix metalloproteinase production by bone marrow mononuclear cells from normal individuals and patients with acute and chronic myeloid leukemia or myelodysplastic syndromes.
Matrix metalloproteinase production by cultured human endometrial stromal cells: identification of interstitial collagenase, gelatinase-A, gelatinase-B, and stromelysin-1 and their differential regulation by interleukin-1 alpha and tumor necrosis factor-alpha.
Matrix Metalloproteinase Responsive Nanoparticles for Synergistic Treatment of Colorectal Cancer via Simultaneous Anti-Angiogenesis and Chemotherapy.
Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.
Matrix metalloproteinase-2 (-1306 c>t) promoter polymorphism and risk of colorectal cancer in the Saudi population.
Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value.
Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) and their tissue inhibitors (TIMP-1 and TIMP-2) in differential diagnosis between low malignant potential (LMP) and malignant ovarian tumours.
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast.
Matrix metalloproteinase-2 (MMP-2) expression and regulation by tumor necrosis factor alpha (TNFalpha) in the bovine corpus luteum.
Matrix metalloproteinase-2 (MMP-2) immunoreactive protein--a new prognostic marker in uveal melanoma?
Matrix metalloproteinase-2 (MMP-2) in T(1-2)N0 breast carcinoma.
Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma.
Matrix metalloproteinase-2 (MMP-2) is associated with the risk for a relapse in postmenopausal patients with node-positive breast carcinoma treated with antiestrogen adjuvant therapy.
Matrix metalloproteinase-2 (MMP-2): A major player in the progression of systemic malignancies besides endometrial serous carcinomas.
Matrix Metalloproteinase-2 -1306 C>T Gene Polymorphism is Associated with Reduced Risk of Cancer: a Meta-analysis.
Matrix metalloproteinase-2 activation modulates glioma cell migration.
Matrix metalloproteinase-2 and -7 expression in colorectal cancer.
Matrix metalloproteinase-2 and -9 activities correlate with the disease-free survival of oral squamous cell carcinoma patients.
Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system.
Matrix metalloproteinase-2 and -9 expression in astrocytic tumors.
Matrix metalloproteinase-2 and -9 involvement in canine tumors.
Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 expression in the biological behavior of Canine and Feline Meningioma.
Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines.
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in paediatric tumour cells. Effects of tumour cell proliferation modulators on gelatinolytic activity.
Matrix metalloproteinase-2 as a superior biomarker for peritoneal deterioration in peritoneal dialysis.
Matrix metalloproteinase-2 as a target for head and neck cancer therapy.
Matrix metalloproteinase-2 cleavage of the ?1 integrin ectodomain facilitates colon cancer cell motility.
Matrix Metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory T(H)2 Cells via an IL-12- and OX40L-Dependent Pathway.
Matrix metalloproteinase-2 contributes to cancer cell migration on collagen.
Matrix metalloproteinase-2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes.
Matrix metalloproteinase-2 expression correlates with cavernous sinus invasion in pituitary adenomas.
Matrix metalloproteinase-2 expression correlates with morphological and immunohistochemical epithelial characteristics in synovial sarcoma.
Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions.
Matrix metalloproteinase-2 expression in stromal tissues is a consistent prognostic factor in stage II colon cancer.
Matrix metalloproteinase-2 gene polymorphism is not associated with increased glioblastoma multiforme susceptibility: an Indian institutional experience.
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Matrix metalloproteinase-2 immunoreactive protein: a marker of aggressiveness in breast carcinoma.
Matrix metalloproteinase-2 in pancreatic juice for diagnosis of pancreatic cancer.
Matrix metalloproteinase-2 involvement in breast cancer progression: a mini-review.
Matrix metalloproteinase-2 is a consistent prognostic factor in gastric cancer.
Matrix metalloproteinase-2 is expressed in melanoma-associated spongiform scleropathy.
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model.
Matrix metalloproteinase-2 mediates ribosomal RNA transcription by cleaving nucleolar histones.
Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
Matrix metalloproteinase-2 Promotes ?v?3 Integrin-Mediated Adhesion and Migration of Human Melanoma Cells by Cleaving Fibronectin.
Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM.
Matrix metalloproteinase-2 status in stromal fibroblasts, not in tumor cells, is a significant prognostic factor in non-small-cell lung cancer.
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
Matrix metalloproteinase-2: A key regulator in coagulation proteases mediated human breast cancer progression through autocrine signaling.
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity.
Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer.
Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse.
Matrix metalloproteinase-9 expression in bladder washes from bladder cancer patients predicts pathological stage and grade.
Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment.
Matrix Metalloproteinase-9 Is a Marker of Heart Failure After Acute Myocardial Infarction.
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis.
Matrix metalloproteinase-cleavable nanocapsules for tumor-activated drug release.
Matrix metalloproteinase-initiated aggregation of melanin nanoparticles as highly efficient contrast agent for enhanced tumor accumulation and dual-modal imaging.
Matrix metalloproteinase-sensitive size-shrinkable nanoparticles for deep tumor penetration and pH triggered doxorubicin release.
Matrix metalloproteinase-triggered denuding of engineered gold nanoparticles for selective cell uptake.
Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura.
Matrix metalloproteinases 2 and 9 and their tissue inhibitors in low malignant potential ovarian tumors.
Matrix metalloproteinases 2 and 9 immunoexpression in prostate carcinoma at the positive margin of radical prostatectomy specimens.
Matrix metalloproteinases 2 and 9 in oral squamous cell carcinomas: manifestation and localization of their activity.
Matrix metalloproteinases 2 and 9 in situ mRNA expression in colorectal tumors from Iraqi patients.
Matrix metalloproteinases 2, 7, and 9 in tumors and sera of patients with breast cancer.
Matrix metalloproteinases and bladder cancer.
Matrix metalloproteinases and E-cadherin immunoreactivity in different basal cell carcinoma histological types.
Matrix metalloproteinases and metastasis.
Matrix metalloproteinases and metastatic cancer.
Matrix metalloproteinases and the thyroid.
Matrix metalloproteinases and their inhibitors in gastric cancer.
Matrix metalloproteinases and their inhibitors.
Matrix Metalloproteinases and Their Tissue Inhibitors in Blood Serum of Patients with Endometrial Cancer: Clinical and Morphological Correlations.
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas.
Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.
Matrix metalloproteinases in blood vessel development in human fetal skin and in cutaneous tumors.
Matrix metalloproteinases in cancer invasion, metastasis and angiogenesis.
Matrix metalloproteinases in carcinoma of unknown primary.
Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression.
Matrix metalloproteinases in normal menstruation.
Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation.
Matrix metalloproteinases in Vietnamese patients with colorectal cancer.
Matrix metalloproteinases may contribute compensationally to tumor invasion in T1 colorectal carcinomas.
Matrix metalloproteinases of human leiomyoma in various stages of tumor growth.
Matrix metalloproteinases play an active role in Wnt1-induced mammary tumorigenesis.
Matrix metalloproteinases, their tissue inhibitors and colorectal cancer staging.
Matrix metalloproteinases, tissue inhibitors of matrix metalloproteinases and angiogenic cytokines in peripheral blood of patients with thyroid cancer.
Matrix metalloproteinases-2 and -9 are expressed in human neuroblastoma: contribution of stromal cells to their production and correlation with metastasis.
Matrix metalloproteinases-2 and -9 in cervical cancer: different roles in tumor progression.
Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
Matrix-directed regulation of pericellular proteolysis and tumor progression.
Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study.
Matrix-metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma.
Matrix-metalloproteinases in bronchopulmonary carcinomas.
Matrix-metalloproteinases in Hodgkin lymphoma.
Matrix-metalloproteinases-2 and -9 production in bovine endometrial cell culture.
May High MMP-2 and TIMP-2 Expressions Increase or Decrease the Aggressivity of Oral Cancer?
MDM2 derived from dedifferentiated liposarcoma extracellular vesicles induces MMP2 production from preadipocytes.
Measuring gelatinase activity in colorectal cancer.
Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs.
Mediastinal Germ Cell Tumor Exhibiting a Discrepancy between Tumor Markers and Imaging: A Case Study.
MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
Melanoma antigen-encoding gene-1 expression in invasive gastric carcinoma: correlation with stage of disease.
Melanoma associated spongiform scleropathy: characterization, biochemical and immunohistochemical studies.
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules.
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Membrane type-1 matrix metalloproteinase stimulates tumour cell-induced platelet aggregation: role of receptor glycoproteins.
Membrane vesicles in ovarian cancer fluids: a new potential marker.
Membrane-associated MMP-2 in human cervical cancer.
Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
Membrane-type matrix metalloproteinase-1 expression and activation of gelatinase A as prognostic markers in advanced pediatric neuroblastoma.
Membrane-type matrix metalloproteinase-1(MT1-MTP) gene is overexpressed in highly invasive hepatocellular carcinomas.
Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion.
Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis.
Membrane-type matrix metalloproteinases.
MERS versus Standard Surgical Approaches for Porcine Vocal Fold Scarring with Adipose Stem Cell Constructs.
Mesenchymal Stem Cells Promote Tumor Progression via Inducing Stroma Remodeling on Rabbit VX2 Bladder Tumor Model.
Messenger RNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human hepatocellular carcinoma.
Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.
Meta-analysis and meta-regression analysis of biomarkers for abdominal aortic aneurysm.
Meta-analysis of association of the matrix metalloproteinase 2 (-735 C/T) polymorphism with cancer risk.
Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma.
Metallopeptidase, neurolysin, as a novel molecular tool for analysis of properties of cancer-producing matrix metalloproteinases-2 and -9.
Metalloprotease-specific poly(ethylene glycol) methyl ether-peptide-doxorubicin conjugate for targeting anticancer drug delivery based on angiogenesis.
Metalloproteinase and TIMP expression by the human breast carcinoma cell line 8701-BC.
Metalloproteinase-2 expression correlates with aggressiveness of cutaneous squamous cell carcinomas.
Metalloproteinase-2, -7 and -9 and tissue inhibitor of metalloproteinase-1 and -2 expression in normal, hyperplastic and neoplastic endometrium: a clinical-pathological correlation study.
Metalloproteinases 1 and 3 as Potential Biomarkers in Breast Cancer Development.
Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis.
Metalloproteinases and cancer invasion.
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
Metalloproteinases in juvenile angiofibroma--a collagen rich tumor.
Metalloproteinases in multiple myeloma: production of matrix metalloproteinase-9 (MMP-9), activation of proMMP-2, and induction of MMP-1 by myeloma cells.
Metalloproteinases in tumor progression: the contribution of MMP-9.
METALLOPROTEINS DURING DEVELOPMENT OF WALKER-256 CARCINOSARCOMA RESISTANT PHENOTYPE.
Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model.
Metastasis of human colon tumor cells in vivo: correlation with the overexpression of plasminogen activators and 72 kDa gelatinase.
Metastatic ability of MXT mouse mammary subpopulations correlates with clonal expression and/or membrane-association of gelatinase A.
Metastatic and non-metastatic colorectal cancer (CRC) cells induce host metalloproteinase production in vivo.
Metastatic Inhibitory and Radical Scavenging Efficacies of Saponins Extracted from the Brittle Star (Ophiocoma erinaceus).
Methanol extract of Elaeagnus glabra, a Korean medicinal plant, inhibits HT1080 tumor cell invasion.
Methylation profiling in non-small cell lung cancer: clinical implications.
Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2/-9 expression mediated by NF-?B activation.
Microenvironment effects on promoting upregulation of matrix metalloproteinases in Bcl-2-overexpressing renal cell carcinoma as a response to doxorubicin treatment inducing the production of metastasis.
Microenvironment influence on human colon adenocarcinoma phenotypes and matrix metalloproteinase-2, p53 and ?-catenin tumor expressions from identical monoclonal cell tumor in the orthotopic model in athymic nude rats.
Microenvironment-induced TIMP2 loss by cancer-secreted exosomal miR-4443 promotes liver metastasis of breast cancer.
Microenvironment-Responsive Delivery of the Cas9 RNA-Guided Endonuclease for Efficient Genome Editing.
Micronutrient synergy--a new tool in effective control of metastasis and other key mechanisms of cancer.
Micropeptide CIP2A-BP encoded by LINC00665 inhibits triple-negative breast cancer progression.
MicroRNA-141 Is Involved in Ulcerative Colitis Pathogenesis via Aiming at CXCL5.
MicroRNA-29 Family Suppresses the Invasion of HT1080 Human Fibrosarcoma Cells by Regulating Matrix Metalloproteinase 2 Expression.
MicroRNA-29a upregulates MMP2 in oral squamous cell carcinoma to promote cancer invasion and anti-apoptosis.
MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN.
MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression.
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
MicroRNA-466 (miR-466) functions as a tumor suppressor and prognostic factor in colorectal cancer (CRC).
MicroRNA-495 attenuates proliferation and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes through attenuating ?-catenin pathway.
MicroRNA-520a-3p suppresses non-small-cell lung carcinoma by inhibition of High Mobility Group Box 1 (HMGB1).
MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-?B signaling.
MicroRNA-mediated extracellular matrix remodeling in squamous cell carcinoma of the oral cavity.
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.
Mid-trimester amniotic fluid pro-inflammatory biomarkers predict the risk of spontaneous preterm delivery in twins: a retrospective cohort study.
Mifepristone alleviates cerebral ischemia-reperfusion injury in rats by stimulating PPAR ?.
Mimicking the tumor microenvironment: Fibroblasts reduce miR-29b expression and increase the motility of ovarian cancer cells in a co-culture model.
miR-135b, a key regulator of malignancy, is linked to poor prognosis in human myxoid liposarcoma.
miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.
miR-22 Suppresses Tumor Invasion and Metastasis in Colorectal Cancer by Targeting NLRP3.
miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases.
miR-29b attenuates tumorigenicity and stemness maintenance in human glioblastoma multiforme by directly targeting BCL2L2.
miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression.
miR-29b inhibits the progression of esophageal squamous cell carcinoma by targeting MMP-2.
miR-361-5p inhibits glioma migration and invasion by targeting SND1.
miR-768-3p is involved in the proliferation, invasion and migration of non-small cell lung carcinomas.
Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis.
Mitotic arrest induced in human DU145 prostate cancer cells in response to KHC-4 treatment.
MMI-166, a selective matrix metalloproteinase inhibitor, promotes apoptosis in human pancreatic cancer.
MMP inhibition blocks fibroblast-dependent skin cancer invasion, reduces vascularization and alters VEGF-A and PDGF-BB expression.
MMP-1 and MMP-2 expression in uterine leiomyosarcoma and correlation with different clinicopathologic parameters.
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
MMP-19: cellular localization of a novel metalloproteinase within normal breast tissue and mammary gland tumours.
MMP-2 activation and stepwise progression of pulmonary adenocarcinoma: analysis of MMP-2 and MMP-9 with gelatin zymography.
MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells.
MMP-2 and MMP-13 affect vasculogenic mimicry formation in large cell lung cancer.
MMP-2 and MMP-9 as prognostic markers for the early detection of urinary bladder cancer.
MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions.
MMP-2 and MMP-9 in lymph-node-positive bladder cancer.
MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.
MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancer.
MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization.
MMP-2 but not MMP-9 associated with COX-2 and survival in gastric cancer.
MMP-2 downregulation mediates differential regulation of cell death via ErbB-2 in glioma xenografts.
MMP-2 expression and correlation with pathology and MRI of glioma.
MMP-2 expression associates with CA 125 and clinical course in endometrial carcinoma.
MMP-2 expression in 102 patients with glottic laryngeal cancer.
MMP-2 expression in uveal melanoma: differential activation status dictated by the cellular environment.
MMP-2 functions as an early response protein in ovarian cancer metastasis.
MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not.
MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors.
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity.
MMP-2 positivity and age less than 40 years increases the risk for recurrence in premenopausal patients with node-positive breast carcinoma.
MMP-2 protein in invasive breast cancer and the impact of MMP-2/TIMP-2 phenotype on overall survival.
MMP-2 release and activation in ovarian carcinoma: the role of fibroblasts.
MMP-2 responsive polymeric micelles for cancer-targeted intracellular drug delivery.
MMP-2 sensitive poly(malic acid) micelles stabilized by ?-? stacking enable high drug loading capacity.
MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
MMP-2-Controlled Transforming Micelles for Heterogeneic Targeting and Programmable Cancer Therapy.
MMP-2-responsive fluorescent nanoprobes for enhanced selectivity of tumor cell uptake and imaging.
MMP-2-responsive gelatin nanoparticles for synergistic tumor therapy.
MMP-2-Sensitive HA End-Conjugated Poly(amidoamine) Dendrimers via Click Reaction To Enhance Drug Penetration into Solid Tumor.
MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells.
MMP-9 and MMP-2 gelatinases and TIMP-1 and TIMP-2 inhibitors in breast cancer: correlations with prognostic factors.
MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis.
MMP-9 secretion and MMP-2 activation distinguish invasive and metastatic sublines of a mouse mammary carcinoma system showing epithelial-mesenchymal transition traits.
MMP-responsive theranostic nanoplatform based on mesoporous silica nanoparticles for tumor imaging and targeted drug delivery.
MMP2 expression is a prognostic marker for primary melanoma patients.
MMP9 mediates MICA shedding in human osteosarcomas.
Modulation of airway remodeling-associated mediators by the antifibrotic compound, pirfenidone, and the matrix metalloproteinase inhibitor, batimastat, during acute lung injury in mice.
Modulation of cell growth and matrix metalloproteinase-2 activation of oral squamous cell carcinoma as a function of culture condition with type I collagen.
Modulation of MMP-2 and MMP-9 by cytokines, mitogens and inhibitors in lung cancer and malignant mesothelioma cell lines.
Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells.
Modulation of type IV collagenase and plasminogen activator in a hamster fibrosarcoma by basement membrane components and lung fibroblasts.
Moesin Up-regulation Is Associated with Enhanced Tumor Progression Imaged Non-invasively in an Orthotopic Mouse Model of Human Glioblastoma.
Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.
Molecular characterization and clinical implications of spindle cells in nasopharyngeal carcinoma: a novel molecule-morphology model of tumor progression proposed.
Molecular characterization and in-silico analysis of the tissue inhibitor of metalloproteinases-3 (TIMP-3) gene of canine mammary tumor.
Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development.
Molecular Decision Tree Algorithms Predict Individual Recurrence Pattern for Locally Advanced Nasopharyngeal Carcinoma.
Molecular determinants of glioma cell migration and invasion.
Molecular docking and inhibition of matrix metalloproteinase-2 by novel difluorinatedbenzylidene curcumin analog.
Molecular dynamics simulations of metalloproteinases types 2 and 3 reveal differences in the dynamic behavior of the S1' binding pocket.
Molecular mechanism about lymphogenous metastasis of hepatocarcinoma cells in mice.
Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases.
Molecular prognostic markers in recurrent and in non-recurrent epithelial ovarian cancer.
Monascus purpureus-fermented rice inhibits tumor necrosis factor-?-induced upregulation of matrix metalloproteinase 2 and 9 in human aortic smooth muscle cells.
Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin.
Monomeric 55-kDa guanidinobenzoatase switches to a serine proteinase activity upon tetramerization. Tetrameric proteinase SP 220 K appears as the native form.
Monomethyl selenium--specific inhibition of MMP-2 and VEGF expression: implications for angiogenic switch regulation.
Morusin Suppresses Cancer Cell Invasion and MMP-2 Expression through ERK Signaling in Human Nasopharyngeal Carcinoma.
Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells.
mRNA concentrations of MIF in subcutaneous abdominal adipose cells are associated with adipocyte size and insulin action.
mRNA expression of matrix metalloproteases and their inhibitors differs in subtypes of renal cell carcinomas.
MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
MT-MMP expression and localisation in human lung and breast cancers.
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts.
MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.
MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells.
Multi-Förster Resonance Energy Transfer-Based Fluorescent Probe for Spatiotemporal Matrix Metalloproteinase-2 and Caspase-3 Imaging.
Multi-layered nanogels with MMP-sheddable PEG masks: Preparation and promotion of tumor cell uptake by controlling surface characteristics.
Multi-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling.
Multi-Stimuli-Responsive Polymeric Prodrug for Enhanced Cancer Treatment.
Multifunctional role of VIP in prostate cancer progression in a xenograft model: Suppression by curcumin and COX-2 inhibitor NS-398.
Multifunctional Self-Assembling Peptide-Based Nanostructures for Targeted Intracellular Delivery: Design, Physicochemical Characterization, and Biological Assessment.
Multiparametric in situ messenger RNA hybridization analysis to detect metastasis-related genes in surgical specimens of human colon carcinomas.
Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma.
Multiparametric in situ mRNA hybridization analysis to predict disease recurrence in patients with colon carcinoma.
Multiple molecular modelling studies on some derivatives and analogues of glutamic acid as matrix metalloproteinase-2 inhibitors.
Multiplex Cytokine Analysis of Aqueous Humor in Juvenile Idiopathic Arthritis-Associated Anterior Uveitis With or Without Secondary Glaucoma.
Multistage nanoparticle delivery system for deep penetration into tumor tissue.
Multistage-responsive nanovehicle to improve tumor penetration for dual-modality imaging-guided photodynamic-immunotherapy.
Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway.
N-Acetylglucosaminyltransferase V triggers overexpression of MT1-MMP and reinforces the invasive/metastatic potential of cancer cells.
N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53.
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
Nanoparticle-mediated local depletion of tumour-associated platelets disrupts vascular barriers and augments drug accumulation in tumours.
NaoXinTong Inhibits the Advanced Atherosclerosis and Enhances the Plaque Stability in Apolipoprotein E Deficient Mice.
Natural human monocyte gelatinase and its inhibitor.
Natural products as a gold mine for selective matrix metalloproteinases inhibitors.
NDV-D90 suppresses growth of gastric cancer and cancer-related vascularization.
Near-infrared triple-helical peptide with quenched fluorophores for optical imaging of MMP-2 and MMP-9 proteolytic activity in vivo.
Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells.
NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer.
Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-? signaling pathway.
Neutralization of MMP-2 and TNFR1 Regulates the Severity of S. aureus-Induced Septic Arthritis by Differential Alteration of Local and Systemic Proinflammatory Cytokines in Mice.
Neutrophil elastase processing of gelatinase A is mediated by extracellular matrix.
Neutrophil-derived serine proteinases enhance membrane type-1 matrix metalloproteinase-dependent tumor cell invasion.
Neutrophils, a candidate biomarker and target for radiation therapy?
New clinical scoring system for prognosis of early recurrence of colorectal liver metastases after surgical treatment.
New enzyme-activated solubility-switchable contrast agent for magnetic resonance imaging: from synthesis to in vivo imaging.
New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: Outside-in signaling and relationship to tumor progression.
New Insights on Old Biomarkers Involved in Tumor Microenvironment Changes and Their Diagnostic Relevance in Non-Small Cell Lung Carcinoma.
New pathway links from cancer-progression determinants to gene expression of matrix metalloproteinases in breast cancer cells.
New radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents.
Newt squamous carcinoma proves phylogenetic conservation of tumors as caricatures of tissue renewal.
Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer model.
NIK- and IKK?-binding protein promotes colon cancer metastasis by activating the classical NF-?B pathway and MMPs.
No correlation between TIMP2 -418 G>C polymorphism and increased risk of cancer: evidence from a meta-analysis.
Nodal promotes growth and invasion in human gliomas.
Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma.
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells.
Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol.
Normal nonmetastatic human trophoblast cells share in vitro invasive properties of malignant cells.
Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic.
Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism.
Novel biomarkers in malignant melanoma.
Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: synthesis, anti-invasive and anti-angiogenic properties.
Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells.
Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model.
Novel ternary vanadium-betaine-peroxido species suppresses H-ras and matrix metalloproteinase-2 expression by increasing reactive oxygen species-mediated apoptosis in cancer cells.
Nuclear factor E2-related factor 2 knockdown enhances glucose uptake and alters glucose metabolism in AML12 hepatocytes.
Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor through Activation of MMP-2.
Nucleophosmin Mutants Promote Adhesion, Migration and Invasion of Human Leukemia THP-1 Cells through MMPs Up-regulation via Ras/ERK MAPK Signaling.
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.
Occurrence of an active form of gelatinase in human gastric and colorectal carcinoma tissues.
Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases.
Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells.
Olea europaea leaf extract and bevacizumab synergistically exhibit beneficial efficacy upon human glioblastoma cancer stem cells through reducing angiogenesis and invasion in vitro.
Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice.
Olmesartan decreases IL-1? and TNF-? levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis.
Oncogenic transformation of human benign prostate hyperplasia with chronic cadmium exposure.
Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines.
Opposite Roles of CCR2 and CX3CR1 Macrophages in Alkali-Induced Corneal Neovascularization.
Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model.
Optical imaging of MMP expression and cancer progression in an inflammation-induced colon cancer model.
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Organ heterogeneity of host-derived matrix metalloproteinase expression and its involvement in multiple-organ metastasis by lung cancer cell lines.
Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors.
Osteopontin alters endothelial and valvular interstitial cell behaviour in calcific aortic valve stenosis through HMGB1 regulation.
Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha /IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways.
Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma.
Osteopontin regulates human glioma cell invasiveness and tumor growth in mice.
Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells.
Osteopontin: it's role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression.
Outline of gelatinase inhibitors as anti-cancer agents: A patent mini-review for 2010-present.
Ovarian aging-like phenotype in the hyperandrogenism-induced murine model of polycystic ovary.
Ovarian carcinoma cells in serous effusions show altered MMP-2 and TIMP-2 mRNA levels.
Overcoming Intrinsic Doxorubicin Resistance in Melanoma by Anti-Angiogenic and Anti-Metastatic Effects of Liposomal Prednisolone Phosphate on Tumor Microenvironment.
Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells.
Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis.
Overexpression of matrix metalloproteinase 2 predicts unfavorable outcome in early-stage non-small cell lung cancer.
Overexpression of matrix metalloproteinase-1 and -9 mRNA is associated with progression of oral dysplasia to cancer.
Overexpression of matrix metalloproteinase-7 and -9 in NSCLC tumor and stromal cells: Correlation with a favorable clinical outcome.
Overexpression of matrix-metalloproteinase-9 in human breast cancer: a potential favourable indicator in node-negative patients.
Overexpression of micro ribonucleic acid-591 inhibits cell proliferation and invasion of malignant pleural mesothelioma cells.
Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma.
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
Overexpression of MMP-9 correlates with growth of small hepatocellular carcinoma.
Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.
Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Sp1-mediated signaling pathways.
Overexpression of protein kinase C-alpha and -beta isozymes by stromal dendritic cells in basal and squamous cell carcinoma.
Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS.
Oxymatrine alleviates periodontitis in rats by inhibiting inflammatory factor secretion and regulating MMPs/TIMP protein expression1.
p16 inhibits matrix metalloproteinase-2 expression via suppression of Sp1-mediated gene transcription.
p16(INK4A) Represses the paracrine tumor-promoting effects of breast stromal fibroblasts.
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
P2RX7 Purinoceptor as a Therapeutic Target-The Second Coming?
p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR.
p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells.
P53 stratification reveals the prognostic utility of matrix metalloproteinase-9 protein expression in glioblastoma.
Palmatine inhibits TRIF-dependent NF-?B pathway against inflammation induced by LPS in goat endometrial epithelial cells.
Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay.
Papillary thyroid carcinoma with different histological patterns.
Paradoxical antiproliferative effect by a murine mammary tumor-derived epithelial cell line.
Partial purification of gelatinases and effect of anti-inflammatory drugs on the tumor necrosis factor-stimulated production of active gelatinase by granulation tissue in culture.
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Pathological function of prostaglandin E2 receptors in transitional cell carcinoma of the upper urinary tract.
Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.
Pattern of collagen fibers and localization of matrix metalloproteinase 2 and 9 during breast cancer invasion.
Pattern of expression of inflammatory markers in adipose tissue of untreated hypertensive patients.
Patterns of MMP-2 and MMP-9 expression in human cancer cell lines.
PD-1 Blockade for Improving the Antitumor Efficiency of Polymer-Doxorubicin Nanoprodrug.
Pediatric adrenocortical tumors: morphological diagnostic criteria and immunohistochemical expression of matrix metalloproteinase type 2 and human leucocyte-associated antigen (HLA) class II antigens Results from the Italian Pediatric Rare Tumor (TREP) Study project.
PEG10 plays a crucial role in human lung cancer proliferation, progression, prognosis and metastasis.
pEGFP-N1-mediated BmK CT expression suppresses the migration of glioma.
PEGylated Cationic Vectors Containing a Protease-Sensitive Peptide as a miRNA Delivery System for Treating Breast Cancer.
PEGylation extends circulation half-life while preserving in vitro and in vivo activity of tissue inhibitor of metalloproteinases-1 (TIMP-1).
Peptide mediated active targeting and intelligent particle size reduction-mediated enhanced penetrating of fabricated nanoparticles for triple-negative breast cancer treatment.
Performance of a new fluorescence-labeled MMP inhibitor to image tumor MMP activity in vivo in comparison to an MMP-activatable probe.
Periodontitis and Endothelial Dysfunction: Periodontal Clinical Parameters and Levels of Salivary Markers Interleukin-1?, Tumor Necrosis Factor-?, Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinases-2 Complex, and Nitric Oxide.
Periodontitis and type 2 diabetes among women with previous gestational diabetes: epidemiological and immunological aspects in a follow-up of three years.
Peritumoral Clefting and Expression of MMP-2 and MMP-9 in Basal Cell Carcinoma of the Skin.
Peroxynitrite inactivates human-tissue inhibitor of metalloproteinase-4.
Phase I and pharmacologic study of the specific matrix metalloproteinase inhibitor BAY 12-9566 on a protracted oral daily dosing schedule in patients with solid malignancies.
Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor, MMI270 (CGS27023A), in patients with advanced solid cancer.
Phase I study of low-dose metronomic temozolomide for recurrent malignant gliomas.
Phase I study of the matrix metalloproteinase inhibitor, BAY 12-9566.
Phorbol ester tumour promoter mediated altered expression and regulation of matrix metalloproteinase-2 in a H-ras transformed cell line capable of benign tumour formation.
Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.
Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and -7 and E-cadherin.
Photodynamic effect in medulloblastoma: downregulation of matrix metalloproteinases and human telomerase reverse transcriptase expressions.
Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester.
Photodynamic Molecular Beacons triggered by MMP-2 and MMP-9: Influence of the distance between photosensitizer and quencher onto photophysical properties and enzymatic activation.
Photothermal/matrix metalloproteinase-2 dual-responsive gelatin nanoparticles for breast cancer treatment.
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Pitavastatin inhibits hepatic steatosis and fibrosis in non-alcoholic steatohepatitis model rats.
Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2.
Plasma levels and diagnostic utility of VEGF, MMP-2 and TIMP-2 in the diagnostics of breast cancer patients.
Plasma Levels of Inflammatory Biomarkers in Peripheral Arterial Disease: Results of a Cohort Study.
Plasma levels of matrix metalloproteinases 2 and 9 correlate with histological grade in breast cancer patients.
Plasma matrix metalloproteinase 9 as biomarker of prostate cancer progression in Dunning (Copenhagen) rats.
Plasma matrix metalloproteinases, cytokines and angiogenic factors in moyamoya disease.
Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells.
Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases.
Plasmatic level of neuroinflammatory markers predict the extent of diffusion-weighted image lesions in hyperacute stroke.
Plasminogen activator activities in short-term tissue cultures of benign prostatic hyperplasia and prostatic carcinoma.
Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer.
Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production.
Pleural fluid tests to identify complicated parapneumonic effusions.
Pleural fluids associated with metastatic lung tumors are rich in progelatinase B/proMMP-9.
Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter is Associated with Cervical Neoplasm Risk in Mexican Women.
Polymorphism of MMP-9 gene is not associated with the risk of urinary cancers: Evidence from an updated meta-analysis.
Polymorphisms in MMP-1, MMP-2, MMP-7, MMP-13 and MT2A do not contribute to breast, lung and colon cancer risk in polish population.
Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.
Polyphenols from Artemisia annua L Inhibit Adhesion and EMT of Highly Metastatic Breast Cancer Cells MDA-MB-231.
Porf-2 Inhibits Tumor Cell Migration Through the MMP-2/9 Signaling Pathway in Neuroblastoma and Glioma.
Positive and negative transcriptional elements of the human type IV collagenase gene.
Positive correlation between inhibitors of matrix metalloproteinase 1 and matrix metalloproteinases in malignant ovarian tumor tissues.
Possible in vivo mechanisms involved in photodynamic therapy using tetrapyrrolic macrocycles.
Possible role of matrix metalloproteinases (MMPs) in hyperostosis of intracranial meningiomas.
Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail.
Posttranscriptional stimulation of endothelial cell matrix metalloproteinases 2 and 1 by endothelioma cells.
Potent anti-cancer effects of citrus peel flavonoids in human prostate xenograft tumors.
Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis.
Potent tumor targeting drug release system comprising MMP-2 specific peptide fragment with self-assembling characteristics.
Potential MMP2-mediated availability of HLA binding, mutant ECM peptides reflects better melanoma survival rates and greater T-cell infiltrates.
Potential Role of Fibroblast-Like Synoviocytes in Joint Damage Induced by Brucella abortus Infection through Production and Induction of Matrix Metalloproteinases.
Potential role of genipin in cancer therapy.
Potential role of M2 TAMs around lymphatic vessels during lymphatic invasion in papillary thyroid carcinoma.
Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives.
Potentiation of scutellarin on human tongue carcinoma xenograft by low-intensity ultrasound.
POU5F1 enhances the invasiveness of cancer stem-like cells in lung adenocarcinoma by upregulation of MMP-2 expression.
PPAR? delivered by Ch-GNPs onto titanium surfaces inhibits implant-induced inflammation and induces bone mineralization of MC-3T3E1 osteoblast-like cells.
PPAR? regulates inflammatory reaction by inhibiting the MAPK/NF-?B pathway in C2C12 skeletal muscle cells.
PPARalpha downregulates airway inflammation induced by lipopolysaccharide in the mouse.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Predicting Novel Antitumor Agents: 3D-Pharmacophore Mapping of ?-N-biaryl Ether Sulfonamide-Based Hydroxamates as Potentially MMP-2 Inhibitors.
Prediction of healing progress of pressure ulcers by distribution analysis of protein markers on necrotic tissue: A retrospective cohort study.
Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry.
Predictive value of lymph node and tumor matrix metalloproteinase expression in the analysis of metastatic periampullary tumors.
Predictors of exacerbations in chronic obstructive pulmonary disease--results from the Bergen COPD cohort study.
Preference of Aerosolized Pirfenidone to Oral Intake: An Experimental Model of Pulmonary Fibrosis by Paraquat.
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.
Preliminary evaluation of inhibition of matrix-metalloprotease MMP-2 and MMP-9 by Passiflora edulis and P foetida aqueous extracts.
Preoperative plasma MMP-2 expression is prognostic in colorectal cancer.
Preoperative radiotherapy and extracellular matrix remodeling in rectal mucosa and tumour matrix metalloproteinases and plasminogen components.
Preoperative Serum Levels of Matrix Metalloproteinase-2 (MMP-2) and Survival of Breast Cancer among Korean Women.
Preparation and characterization of a novel chimeric protein VEGI-CTT in Escherichia coli.
Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion.
Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas.
Presence of Myofibroblasts and Expression of Matrix Metalloproteinase-2 (MMP-2) in Ameloblastomas Correlate with Rupture of the Osseous Cortical.
Prevalence of vascular-endothelial growth factor, matrix metalloproteinases and tissue inhibitors of metalloproteinases in primary breast cancer.
Primary breast myoepithelial cells exert an invasion-suppressor effect on breast cancer cells via paracrine down-regulation of MMP expression in fibroblasts and tumour cells.
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice.
Probing the S1' Site for the Identification of Non-Zinc-Binding MMP-2 Inhibitors.
Production and characterization of a human single-chain Fv to collagenase IV.
Production of bioengineered cancer tissue constructs in vitro: epithelium-mesenchyme heterotypic interactions.
Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.
Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study.
Profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases proteins in bladder urothelial carcinoma.
Progelatinase A activation during tumor cell invasion.
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Progesterone and 1,25-dihydroxyvitamin D? inhibit endometrial cancer cell growth by upregulating semaphorin 3B and semaphorin 3F.
Progestin suppresses matrix metalloproteinase production in endometrial cancer.
Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion.
Prognostic and diagnostic implications of MMP-2, MMP-9, and VEGF-? expressions in colorectal cancer.
Prognostic factors in papillary thyroid cancer: an evaluation of 601 consecutive patients.
Prognostic markers in pheochromocytoma.
Prognostic relevance of MMP-2 (72-kD collagenase IV) in gastric cancer.
Prognostic relevance of serum levels of the angiogenic peptide bFGF in advanced carcinoma of the head and neck treated by primary radiochemotherapy.
Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection.
Prognostic Significance of Ets-1 and the Matrix Metalloproteinase-2 to Tissue Inhibitor of Matrix Metalloproteinase-2 Ratio in Egyptian Epithelial Ovarian Cancer Patients.
Prognostic significance of extracellular matrix degrading enzymes-cathepsin L and matrix metalloproteases-2 [MMP-2] in human pancreatic cancer.
Prognostic Significance of Extracellular Matrix Metalloproteinase Inducer and Matrix Metalloproteinase 2 in Epithelial Ovarian Cancer.
Prognostic significance of matrix metalloproteinase-2 in gynecological cancer: a systemic review of the literature and meta-analysis.
Prognostic significance of matrix metalloproteinase-2, -8, -9, and -13 in oral tongue cancer.
Prognostic significance of matrix metalloproteinases 2 and 9 in bladder cancer.
Prognostic significance of matrix metalloproteinases 2 and 9 in endometrial cancer.
Prognostic significance of matrix metalloproteinases-2 activation ratio in renal cell carcinoma.
Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in human cutaneous melanoma.
Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients.
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Prognostic significance of the expression of nuclear eukaryotic translation initiation factor 5A2 in human melanoma.
Prognostic significance of the immunoexpression of matrix metalloproteinase MMP2 and its inhibitor TIMP2 in laryngeal cancer.
Prognostic value of matrix metalloproteinase-2 (MMP-2) expression in endometrial endometrioid adenocarcinoma.
Prognostic value of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9) and aminopeptidase N/CD13 in breast cancer patients.
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma.
Prognostic value of matrix metalloproteinases in oral squamous cell carcinoma.
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma.
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Prognostic value of the cancer oncogene Kelch-like 6 in gastric cancer.
Prognostic value of tumor progression-related gene expression in colorectal cancer patients.
Prognostic values of ETS-1, MMP-2 and MMP-9 expression and co-expression in breast cancer patients.
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Programmed drug delivery system based on optimized "size decrease and hydrophilicity/hydrophobicity transformation" for enhanced hepatocellular carcinoma therapy of doxorubicin.
Programmed packaging of mesoporous silica nanocarriers for matrix metalloprotease 2-triggered tumor targeting and release.
Progression elevated gene-3 (PEG-3) induces pleiotropic effects on tumor progression: modulation of genomic stability and invasion.
Progression of mycosis fungoides is associated with changes in angiogenesis and expression of the matrix metalloproteinases 2 and 9.
Progression of non-small cell lung cancer: diagnostic and prognostic utility of matrix metalloproteinase-2, C-reactive protein and serum amyloid A.
Progressive upregulation of metastasis-related genes in human colon cancer cells implanted into the cecum of nude mice.
Prolonged butyrate treatment inhibits the migration and invasion potential of HT1080 tumor cells.
Prominent expression of metalloproteinases in early stages of ovarian tumorigenesis.
Propionibacterium acnes stimulates pro-matrix metalloproteinase-2 expression through tumor necrosis factor-alpha in human dermal fibroblasts.
Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate.
Protease-Activable Cell-Penetrating Peptide-Protoporphyrin Conjugate for Targeted Photodynamic Therapy in Vivo.
Proteases and invasion by metastatic tumor-cells - clinical implications for prostate-cancer.
Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in rats.
Protective effects of fermented rice vinegar sediment (Kurozu moromimatsu) in a diethylnitrosamine-induced hepatocellular carcinoma animal model.
Protective effects of selective mineralocorticoid receptor antagonist against aortic aneurysm progression in a novel murine model.
Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas.
Protein Expression of MMP-2 and MT1-MMP in Actinic Keratosis, Squamous Cell Carcinoma of the Skin, and Basal Cell Carcinoma.
Protein inhibitor of activated STAT-1 is downregulated in gastric cancer tissue and involved in cell metastasis.
Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer.
Protein-bound polysaccharide PSK inhibits tumor invasiveness by down-regulation of TGF-beta1 and MMPs.
Protein-free culture of the human pancreatic cancer cell line, SUIT-2.
Proteolipid protein 2 is associated with melanoma metastasis.
Proteolysis in human breast and colorectal cancer.
Proteolysis-Responsive Rolling Circle Transcription Assay Enabling Femtomolar Sensitivity Detection of a Target Protease Biomarker.
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Proteolytic imbalance is reversed after therapeutic surgery in breast cancer patients.
Proteome profiling of U2OS cell line in response to a prenylphenol antibiotic isolated from a phytopathogenic fungus.
Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-?B pathway and MMP-2 production by targeting RhoB activation.
PSY-1, a Taxus chinensis var. mairei extract, inhibits cancer cell metastasis by interfering with MMPs.
Psychological Stress Up-Regulates CD147 Expression Through Beta-Arrestin1/ERK to Promote Proliferation and Invasiveness of Glioma Cells.
Pterostilbene Inhibits Adipocyte Conditioned-Medium-Induced Colorectal Cancer Cell Migration through Targeting FABP5-Related Signaling Pathway.
Pulsed Electromagnetic Field Modulates Tendon Cells Response in IL-1?-Conditioned Environment.
Purification and characterization of catalytic domains of gelatinase A with or without fibronectin insert for high-throughput inhibitor screening.
Purification of a gelatin-degrading type IV collagenase secreted by ras oncogene-transformed fibroblasts.
Pyridine-Containing Macrocycles Display MMP-2/9 Inhibitory Activity and Distinct Effects on Migration and Invasion of 2D and 3D Breast Cancer Models.
QSAR modelling on a series of arylsulfonamide-based hydroxamates as potent MMP-2 inhibitors.
Quantification of fibronectin as a method to assess ex vivo extracellular matrix remodeling.
Quantification of matrix metalloproteinase activity in plasma of patients enrolled in a BAY 12-9566 phase I study.
Quantitative analysis of matrix metalloproteinase-2 mRNA expression in central and peripheral regions of gliomas.
Quantitative analysis of melanocytic tissue array reveals inverse correlation between activator protein-2alpha and protease-activated receptor-1 expression during melanoma progression.
Quantitative cell dispersion analysis: new test to measure tumor cell aggressiveness.
Quantitative detection of TIMP-3 promoter hypermethylation and its prognostic significance in esophageal squamous cell carcinoma.
Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples.
Quantitative proteomics suggest a potential link between early embryonic death and trisomy 16.
Quantum dots based molecular beacons for in vitro and in vivo detection of MMP-2 on tumor.
Quercetin Suppresses the Migration and Invasion in Human Colon Cancer Caco-2 Cells Through Regulating Toll-like Receptor 4/Nuclear Factor-kappa B Pathway.
Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases.
Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition.
Radiation therapy to a primary tumor accelerates metastatic growth in mice.
Radiation-enhancement of MDA-MB-231 breast cancer cell invasion prevented by a cyclooxygenase-2 inhibitor.
Radiation-induced lipoprotein-associated phospholipase A2 increases lysophosphatidylcholine and induces endothelial cell damage.
Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide.
Raf activation by Ras and promotion of cellular metastasis require phosphorylation of prohibitin in the raft domain of the plasma membrane.
Raf kinase inhibitor protein suppresses nuclear factor-?B-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression.
Rapid activation of matrix metalloproteinase-2 by glioma cells occurs through a posttranslational MT1-MMP-dependent mechanism.
Rapid and highly efficient capture and release of cancer cells using polymeric microfibers immobilized with enzyme-cleavable peptides.
Rapid release of matrix metalloproteinase (MMP)-2 by thrombin in the rat aorta: modulation by protein tyrosine kinase/phosphatase.
Rapid trafficking of membrane type 1-matrix metalloproteinase to the cell surface regulates progelatinase a activation.
Ras pathway is required for the activation of MMP-2 secretion and for the invasion of src-transformed 3Y1.
Ras-related protein Rap2c promotes the migration and invasion of human osteosarcoma cells.
Ratiometric Imaging of MMP-2 Activity Facilitates Tumor Detection Using Activatable Near-Infrared Fluorescent Semiconducting Polymer Nanoparticles.
Realgar Nanoparticles Inhibit Migration, Invasion and Metastasis in a Mouse Model of Breast Cancer by Suppressing Matrix Metalloproteinases and Angiogenesis.
Recent advances in the regulation of matrix metalloproteinase 2 activation: from basic research to clinical implication (Review).
Recent opportunities in matrix metalloproteinase inhibitor drug design for cancer.
RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata.
RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines.
Recombinant CBD-HepII polypeptide of fibronectin inhibits alphavbeta3 signaling and hematogenous metastasis of tumor.
Recombinant expression and downstream processing of the disulfide-rich tumor-targeting peptide chlorotoxin.
Recombinant human prothrombin kringle-2 inhibits B16F10 melanoma metastasis through inhibition of neovascularization and reduction of matrix metalloproteinase expression.
Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting ?5?1 integrin to downregulate Akt and MMP-2.
Red ginseng extract reduced metastasis of colon cancer cells in vitro and in vivo.
Redox- and MMP-2-sensitive drug delivery nanoparticles based on gelatin and albumin for tumor targeted delivery of paclitaxel.
Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.
Reduction of alachlor-induced olfactory mucosal neoplasms by the matrix metalloproteinase inhibitor Ro 28-2653.
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).
Regulation of gelatinase production and invasiveness by organ-specific fibroblasts in high- and low-metastatic clones from murine RCT sarcoma.
Regulation of gelatinases expression by cytokines, endotoxin, and pharmacological agents in the human osteoarthritic knee.
Regulation of gelatinases in human airway smooth muscle cells: mechanism of progelatinase A activation.
Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid.
Regulation of kinesin expression and type IV collagenase secretion in invasive human prostate PC-3 tumor sublines.
Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons.
Regulation of matrix metalloproteinase-9 gene expression and cell migration by NF-kappaB in response to CpG-oligodeoxynucleotides in RAW 264.7 cells.
Regulation of matrix metalloproteinases - their role in tumor invasion and metastasis.
Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.
Regulation of MMP-9 (92 kDa type IV collagenase/gelatinase B) expression in stromal cells of human giant cell tumor of bone.
Regulation of MT1-MMP and MMP-2 by the serpin PEDF: a promising new target for metastatic cancer.
Regulation of the Mr 72,000 type IV collagenase by the type I insulin-like growth factor receptor.
Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma.
Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells.
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Relationship between metalloprotease expression in tumour and stromal cells and aggressive behaviour in prostate carcinoma: Simultaneous high-throughput study of multiple metalloproteases and their inhibitors using tissue array analysis of radical prostatectomy samples.
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Relationship between the expression of VEGF signal components and matrix metalloproteinases in ovarian tumors.
Relationships Between Immunophenotype, Ki-67 Index, Microvascular Density, Ep-CAM/P-cadherin, and MMP-2 Expression in Early-stage Invasive Ductal Breast Cancer.
Relationships between the level of matrix metalloproteinase-2 and tumor size of breast cancer.
Relative expression of ?-smooth muscle actin and matrix metalloproteinases-2 in ameloblastoma of a black African sub-population.
Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma.
Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential.
Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers.
Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells.
Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel.
Reliability of tumor markers, chemokines, and metastasis-related molecules in serum.
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2.
Reoxygenation using a novel CO2 therapy decreases the metastatic potential of osteosarcoma cells.
Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation.
Requirement of arsenic biomethylation for oxidative DNA damage.
Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells.
Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-?B Pathway.
Retinoic acid stimulates meningioma cell adhesion to the extracellular matrix and inhibits invasion.
Retinoic acid synergizes with cyclic AMP to enhance MMP-2 basal promoter activity.
Retraction: Hyperbaric oxygen activates discoidin domain receptor 2 via tumour necrosis factor-? and the p38 MAPK pathway to increase vascular smooth muscle cell migration through matrix metalloproteinase 2.
Reverse transcription-polymerase chain reaction phenotyping of metalloproteinases and inhibitors involved in tumor matrix invasion.
Reversible Smad-dependent signaling between tumor suppression and oncogenesis.
Reversion-inducing-cysteine-rich protein with Kazal motif is involved in intimal hyperplasia in carotid arteries: a new insight in the prevention of restenosis after vascular angioplasty.
Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo.
Risedronate inhibits human osteosarcoma cell invasion.
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion.
Role of crocin in several cancer cell lines: An updated review.
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine-Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy.
Role of extracellular matrix in breast cancer development: a brief update.
Role of fibrillar Tenascin-C in metastatic pancreatic cancer.
Role of GPER on proliferation, migration and invasion in ligand-independent manner in human ovarian cancer cell line SKOV3.
Role of immunohistochemical overexpression of matrix metalloproteinases MMP-2 and MMP-11 in the prognosis of death by ovarian cancer.
Role of interleukin 10 and transforming growth factor beta1 in the angiogenesis and metastasis of human prostate primary tumor lines from orthotopic implants in severe combined immunodeficiency mice.
Role of interleukin-8 in tumor growth and metastasis of human melanoma.
Role of L1 cell adhesion molecule (L1CAM) in the metastatic cascade: promotion of dissemination, colonization, and metastatic growth.
Role of matrix metalloproteinase-2 in ethanol-induced invasion by breast cancer cells.
Role of matrix metalloproteinase-9 in the basement membrane destruction of superficial urothelial carcinomas.
Role of matrix metalloproteinases 2 and 9 in determination of invasive potential of pancreatic tumors.
Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain.
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with ?5?1 integrin in glioma.
Role of MMP-9 and its tissue inhibitor TIMP-1 in human osteosarcoma: findings in 42 patients followed for 1-16 years.
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
Role of N-acetylcysteine and GSH redox system on total and active MMP-2 in intestinal myofibroblasts of Crohn's disease patients.
Role of phospholipase D in laminin-induced production of gelatinase A (MMP-2) in metastatic cells.
Role of PTHrp and PTHrp-engaged pathways in MCF-7 cells migration/invasion.
Role of reactive oxygen species (ROS), metalloproteinase-2 (MMP-2) and interleukin-6 (IL-6) in direct interactions between tumour cell spheroids and endothelial cell monolayer.
Role of serum matrix metalloproteinase-2 and -9 to predict breast cancer progression.
Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.
Role of the matrix metalloproteinase and tissue inhibitors of metalloproteinase families in noninvasive and invasive tumors transplanted in mice with severe combined immunodeficiency.
Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells.
Role of tumor necrosis factor-alpha in the premature rupture of membranes and preterm labor pathways.
Role of tumor-derived granulocyte-macrophage colony-stimulating factor in mice bearing a highly invasive and metastatic mammary carcinoma.
Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma.
Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.
ROR2 promotes the epithelial-mesenchymal transition by regulating MAPK/p38 signaling pathway in breast cancer.
Russian study of morphological prognostic factors characterization in BRAF-mutant cutaneous melanoma.
Ryk is essential for Wnt-5a-dependent invasiveness in human glioma.
S-adenosylmethionine, a methyl donor, up regulates tissue inhibitor of metalloproteinase-2 in colorectal cancer.
S-Allylcysteine reduces breast tumor cell adhesion and invasion.
S-nitroso-N-acetylcysteine attenuates liver fibrosis in cirrhotic rats.
S-Nitrosocaptopril prevents cancer metastasis in vivo by creating the hostile bloodstream microenvironment against circulating tumor cells.
S100A4 antisense oligodeoxynucleotide suppresses invasive potential of neuroblastoma cells.
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells.
S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells.
Salvianolic acid A suppresses MMP-2 expression and restrains cancer cell invasion through ERK signaling in human nasopharyngeal carcinoma.
Salvianolic acid B from Salvia miltiorrhiza inhibits tumor necrosis factor-alpha (TNF-alpha)-induced MMP-2 upregulation in human aortic smooth muscle cells via suppression of NAD(P)H oxidase-derived reactive oxygen species.
Salvianolic acid B protects from pulmonary microcirculation disturbance induced by lipopolysaccharide in rat.
Saponins derived from the roots of Platycodon grandiflorum inhibit HT-1080 cell invasion and MMPs activities: regulation of NF-kappaB activation via ROS signal pathway.
SB203580, a p38 mitogen-activated protein kinase inhibitor, suppresses the development of endometriosis by down-regulating proinflammatory cytokines and proteolytic factors in a mouse model.
Screening of the residual normal ovarian tissue adjacent to orthotopic epithelial ovarian carcinomas in nude mice.
SCUBE3 is an endogenous TGF-? receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer.
Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.
Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a.
Secretome protein signature of human pancreatic cancer stem-like cells.
Selected Matrix Metalloproteinases (MMP-2, MMP-7) and Their Inhibitor (TIMP-2) in Adult and Pediatric Cancer.
Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries.
Selection of peptide inhibitor to matrix metalloproteinase-2 using phage display and its effects on pancreatic cancer cell lines PANC-1 and CFPAC-1.
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis.
Selective gelatinase inhibitor peptide is effective in targeting tongue carcinoma cell tumors in vivo.
Selective gene transfer to endometrial cancer cells by a polymer against matrix metalloproteinase 2 (MMP-2).
Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment.
Selective photodynamic effects on cervical cancer cells provided by P123 Pluronic®-based nanoparticles modulating hypericin delivery.
Selective water-soluble gelatinase inhibitor prodrugs.
Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways.
SEMA4D Knockdown Attenuates ?-Catenin-Dependent Tumor Progression in Colorectal Cancer.
Semi-quantitative expression of tissue inhibitor of matrix metalloproteinase-2 in cancer of uterine cervix.
Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis.
Sensitive surface enhanced Raman scattering multiplexed detection of matrix metalloproteinase 2 and 7 cancer markers.
Seprase, a membrane-type serine protease, has different expression patterns in intestinal- and diffuse-type gastric cancer.
Sequential activation and production of matrix metalloproteinase-2 during breast cancer progression.
Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy.
Serous and mucinous ovarian tumors express different profiles of MMP-2, -7, -9, MT1-MMP, and TIMP-1 and -2.
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma.
Serum levels and tissue expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinases 2 (TIMP-2) in colorectal cancer patients.
Serum levels of matrix metalloproteinase 2 in patients with breast cancer.
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients.
Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their tissue natural inhibitors in breast tumors.
Serum Levels of MMP9 and MMP2 in Patients with Oral Squamous Cell Carcinoma.
Serum markers of matrix turnover as predictors for the evolution of colorectal cancer metastasis under chemotherapy.
Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients.
Serum matrix metalloproteinase-2 in patients with malignant melanoma.
Serum metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in lung carcinoma patients.
Serum MMPs and TIMPs: May be predictors of breast carcinogenesis?
Sesquiterpene lactone Zaluzanin D alters MMP-9 promoter methylation in differentiated THP-1 monocytic cells and down regulates inflammatory cytokines IL-1? and TNF-?.
SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells.
Severity of Plasma Leakage Is Associated With High Levels of Interferon ?-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
Sevoflurane and thiopental preconditioning attenuates the migration and activity of MMP-2 in U87MG glioma cells.
Shed membrane fragment-associated markers for endometrial and ovarian cancers.
Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer.
Shenkang VII Recipe Attenuates Unilateral Ureteral Obstruction-induced Renal Fibrosis via TGF-?/Smad, NF-?B and SHH Signaling Pathway.
Short hairpin RNA targeting autotaxin reduces human gastric carcinoma AGS cell proliferative, migratory and invasive capabilities in vitro and causes tumor regression in vivo.
Short interfering RNA directed against Slug blocks tumor growth, metastasis formation, and vascular leakage in bladder cancer.
ShRNA knock-down of CXCR7 inhibits tumour invasion and metastasis in hepatocellular carcinoma after transcatheter arterial chemoembolization.
ShRNA-mediated matrix metalloproteinase-2 gene silencing protects normal cells and sensitizes cancer cells against ionizing-radiation induced damage.
Significance of lymphatic invasion and cancer invasion-related proteins on lymph node metastasis in gastric cancer.
Significance of matrix metalloproteinases and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
Significance of MMP-2 expression in prostate cancer: an immunohistochemical study.
Significant Relation of Tissue Inhibitor of Matrix Metalloproteinase-2 and its Combination With Matrix Metalloproteinase-2 to Survival of Patients With Cancer of Uterine Cervix.
Silence of Stomatin-Like Protein 2 Represses Migration and Invasion Ability of Human Liver Cancer Cells via Inhibiting the Nuclear Factor Kappa B (NF-?B) Pathway.
Silencing cAMP-response element-binding protein (CREB) identifies CYR61 as a tumor suppressor gene in melanoma.
Silencing KRAS Overexpression in Cadmium-Transformed Prostate Epithelial Cells Mitigates Malignant Phenotype.
Silencing of calpain expression reduces the metastatic potential of human osteosarcoma cells.
Silencing of HMGA2 suppresses cellular proliferation, migration, invasion, and epithelial-mesenchymal transition in bladder cancer.
Silencing of LINC00461 enhances radiosensitivity of lung adenocarcinoma cells by down-regulating HOXA10 via microRNA-195.
Silencing of the Long Non-Coding RNA TTN-AS1 Attenuates the Malignant Progression of Osteosarcoma Cells by Regulating the miR-16-1-3p/TFAP4 Axis.
Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways.
Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway.
Silibinin inhibits the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2.
Silymarin-loaded Eudragit(®) RS100 nanoparticles improved the ability of silymarin to resolve hepatic fibrosis in bile duct ligated rats.
Similarities of in situ mRNA expression between gelatinase A (MMP-2) and type I procollagen in human gastrointestinal carcinoma: comparison with granulation tissue reaction.
Simultaneous presence of unsaturation and long alkyl chain at P'1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies.
Simvastatin Suppresses Human Breast Cancer Cell Invasion by Decreasing the Expression of Pituitary Tumor-Transforming Gene 1.
Sine oculis homeobox homolog 1 promotes ?5?1-mediated invasive migration and metastasis of cervical cancer cells.
Single-nucleotide polymorphisms and haplotypes of membrane type 1-matrix metalloproteinase in susceptibility and clinical significance of squamous cell neoplasia of uterine cervix in taiwan women.
SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells.
SKI-606 (Bosutinib) Blocks Prostate Cancer Invasion, Growth, and Metastasis In vitro and In vivo through Regulation of Genes Involved in Cancer Growth and Skeletal Metastasis.
Skin property can predict the development of skin tears among elderly patients: a prospective cohort study.
Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells.
Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers.
Smart Nanodrug with Nuclear Localization Sequences in the Presence of MMP-2 To Overcome Biobarriers and Drug Resistance.
SNS-032 prevents hypoxia-mediated glioblastoma cell invasion by inhibiting hypoxia inducible factor-1alpha expression.
Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular signal-regulated kinase/matrix metalloproteinase signaling in a mouse model of lung carcinoma.
Sodium caffeate induces endothelial cell apoptosis and inhibits VEGF expression in cancer cells.
Sodium Intake Is associated With Endothelial Damage Biomarkers and Metabolic Dysregulation.
Solanine induces mitochondria-mediated apoptosis in human pancreatic cancer cells.
Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.
Soluble form of ephrinB2 inhibits xenograft growth of squamous cell carcinoma of the head and neck.
Soluble IL-6R alpha upregulated IL-6, MMP-1 and MMP-2 secretion in bone marrow stromal cells.
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor.
Sorafenib suppresses the epithelial-mesenchymal transition of hepatocellular carcinoma cells after insufficient radiofrequency ablation.
Soybean saponin inhibits tumor cell metastasis by modulating expressions of MMP-2, MMP-9 and TIMP- 2.
SPARC is associated with gastric cancer progression and poor survival of patients.
SPARC/osteonectin induces matrix metalloproteinase 2 activation in human breast cancer cell lines.
SPARCL1 is a novel predictor of tumor recurrence and survival in hilar cholangiocarcinoma.
Spatial controlled multistage nanocarriers through hybridization of dendrimers and gelatin nanoparticles for deep penetration and therapy into tumor tissue.
Spatiotemporal expression profile of proteases and immunological, angiogenic, hormonal and apoptotic mediators in rat placenta before and during intrauterine trophoblast migration.
Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells.
Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis.
Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase.
Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of SGK-1.
Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors.
Squamous cell carcinoma growth in mice and in culture is regulated by c-Jun and its control of matrix metalloproteinase-2 and -9 expression.
Src kinase regulates metalloproteinase-9 secretion induced by type IV collagen in MCF-7 human breast cancer cells.
Stage-specific expression analysis ofMMP-2 & MMP-9 in laryngeal carcinoma.
Standardized Salvia miltiorrhiza extract suppresses hepatic stellate cell activation and attenuates steatohepatitis induced by a methionine-choline deficient diet in mice.
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.
Stat3 Is Involved in Angiotensin II-Induced Expression of MMP2 in Gastric Cancer Cells.
Status of research on matrix metalloproteinases (MMPs) in India.
Stimulation of matrix metalloproteinase-9 expression in human fibrosarcoma cells by synthetic matrix metalloproteinase inhibitors.
Stimulation of the 92-kD type IV collagenase promoter and enzyme expression in human melanoma cells.
Stimulation of type IV collagenase expression by linoleic acid in a metastatic human breast cancer cell line.
Stoichiometric expression of MMP-2/TIMP-2 in benign and malignant tumours of the salivary gland.
Stomach Cancer: Interconnection between the Redox State, Activity of MMP-2, MMP-9 and Stage of Tumor Growth.
Stress hormone-mediated invasion of ovarian cancer cells.
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.
Stromal cells as the major source for matrix metalloproteinase-2 in cutaneous melanoma.
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.
Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast.
Stromal expression of matrix metalloproteinase 2 in cancer-associated fibroblasts is strongly related to human epidermal growth factor receptor 2 status in invasive breast carcinoma.
Stromal fibroblasts adjacent to invasive thyroid tumors: expression of gelatinase A but not stromelysin 3 mRNA.
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment.
Stromal-epithelial interaction in type IV collagenase expression and activation: The role in cancer metastasis.
Stromelysin-3 mRNA expression and malignancy: comparison with clinicopathological features and type IV collagenase mRNA expression in breast tumors.
Strong significant correlation between MMP-9 and systemic symptoms in patients with localized renal cell carcinoma.
Structural characterization of the mesangial cell type IV collagenase and enhanced expression in a model of immune complex-mediated glomerulonephritis.
Studies of type IV collagenase regulation by hypoxia.
Studies on the expression of alpha(v)beta3 integrin receptors in non-malignant and malignant human cervical tumor tissues.
Study on antitumor activities of the chrysin-chromene-spirooxindole on Lewis lung carcinoma C57BL/6 mice in vivo.
Study on Medication Rules of Traditional Chinese Medicine against Antineoplastic Drug-Induced Cardiotoxicity Based on Network Pharmacology and Data Mining.
Study on the expression of p53 and MMP-2 in patients with lung cancer after interventional therapy.
Subcurative radiation significantly increases proliferation, invasion, and migration of primary GBM in vivo.
Suberoylanilide hydroxamic acid (Zolinza/vorinostat) sensitizes TRAIL-resistant breast cancer cells orthotopically implanted in BALB/c nude mice.
Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model.
Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma.
Substrate-zymography: a still worthwhile method for gelatinases analysis in biological samples.
Sulphonamide 1,4-dithia-7-azaspiro[4,4]nonane derivatives as gelatinase A inhibitors.
Superoxide- and NO-dependent mechanisms of antitumor and antimetastatic effect of L-arginine hydrochloride and coenzyme Q10.
Suppression of carbonyl reductase expression enhances malignant behaviour in uterine cervical squamous cell carcinoma: Carbonyl reductase predicts prognosis and lymph node metastasis.
Suppression of hepatocarcinoma model in vitro and in vivo by ECRG2 delivery using adenoviral vector.
Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion.
Suppression of membrane-type 1 matrix metalloproteinase (MMP)-mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product, N-Tes.
Suppression of MMP-2 attenuates TNF-? induced NF-?B activation and leads to JNK mediated cell death in glioma.
Suppression of phospho-p85?-GTP-Rac1 lipid raft interaction by bichalcone analog attenuates cancer cell invasion.
Suppression of tumor cell invasiveness and in vivo tumor growth by microRNA-874 in non-small cell lung cancer.
Suppression of tumor cell invasiveness by hydrolyzable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity.
Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions.
Supramolecular Aggregation-Induced Emission Nanodots with Programmed Tumor Microenvironment Responsiveness for Image-Guided Orthotopic Pancreatic Cancer Therapy.
Surfactin from Bacillus subtilis attenuates ambient air particulate matter-promoted human oral cancer cells metastatic potential.
Survey of risk factors contributed to lymphatic metastasis in patients with oral tongue cancer by immunohistochemistry.
SV40 T/t-common polypeptide inhibits angiogenesis and growth of HER2-overexpressing human ovarian cancer.
Synergistic and protective effect of atorvastatin and amygdalin against histopathological and biochemical alterations in Sprague-Dawley rats with experimental endometriosis.
Synergistic anticancer effects of timosaponin AIII and ginsenosides in MG63 human osteosarcoma cells.
Synergistic effects of Endostar combined with ?-elemene on malignant ascites in a mouse model.
Synergistic efficacy of Cullin1 and MMP-2 expressions in diagnosis and prognosis of colorectal cancer.
Synergistic induction of cancer cell migration regulated by G?? and phosphatidylinositol 3-kinase.
Synergistic Inhibitory Effect of Traditional Chinese Medicine Astragaloside IV and Curcumin on Tumor Growth and Angiogenesis in an Orthotopic Nude-Mouse Model of Human Hepatocellular Carcinoma.
Synthesis and anticancer activities of ageladine A and structural analogs.
Synthesis and degradation of basement membranes in benign and malignant salivary gland tumours. A study by in situ hybridization.
Synthesis and Evaluation of a Novel Hydroxamate Based Fluorescent Photoprobe for Imaging of Matrix Metalloproteinases.
Synthesis and preliminary evaluation in tumor bearing mice of new (18)f-labeled arylsulfone matrix metalloproteinase inhibitors as tracers for positron emission tomography.
Synthesis of a beta-tetrapeptide analog as a mother compound for the development of matrix metalloproteinase-2-imaging agents.
Synthesis, anticancer activity, structure-activity relationship and binding mode of interaction studies of substituted pentanoic acids.
Synthesis, Biological Evaluation, and Docking of Dihydropyrazole Sulfonamide Containing 2-hydroxyphenyl Moiety: A Series of Novel MMP-2 Inhibitors.
Synthesis, Kinetic Characterization and Metabolism of Diastereomeric 2-(1-(4-Phenoxyphenylsulfonyl)ethyl)thiiranes as Potent Gelatinase and MT1-MMP Inhibitors.
Synthesis, structure and characterization of novel Cd(II) and Zn(II) complexes with the condensation product of 2-formylpyridine and selenosemicarbazide Antiproliferative activity of the synthesized complexes and related selenosemicarbazone complexes.
Synthesized tetrahydroisoquinoline alkaloid exerts anticancer effects at least in part by suppressing NF??B?regulated proteins in A549 human lung cancer cells.
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
Systemic and alveolar inflammatory response in the dependent and nondependent lung in patients undergoing lung resection surgery: A prospective observational study.
Systemic delivery of protein nanocages bearing CTT peptides for enhanced imaging of MMP-2 expression in metastatic tumor models.
Systemic hypoxia potentiates anti-tumor effects of metformin in hepatocellular carcinoma in mice.
Systemic Th17-like cytokine pattern in gangrenous appendicitis but not in phlegmonous appendicitis.
SZ-117, a monoclonal antibody against matrix metalloproteinase-2 inhibits tumor cell-mediated angiogenesis.
Tacorin, an extract from Ananas comosus stem, stimulates wound healing by modulating the expression of tumor necrosis factor ?, transforming growth factor ? and matrix metalloproteinase 2.
Target-activated transcription for the amplified sensing of protease biomarkers.
Target-selective activation of a TNF prodrug by urokinase-type plasminogen activator (uPA) mediated proteolytic processing at the cell surface.
Targeted Delivery of Secretory Promelittin via Novel Poly(lactone-co-?-amino ester) Nanoparticles for Treatment of Breast Cancer Brain Metastases.
Targeted MMP-2 responsive chimeric polymersomes for therapy against colorectal cancer.
Targeted therapy against VEGFR and EGFR with ZD6474 enhances the therapeutic efficacy of irradiation in an orthotopic model of human non-small-cell lung cancer.
Targeting and Microenvironment-Responsive Lipid Nanocarrier for the Enhancement of Tumor Cell Recognition and Therapeutic Efficiency.
Targeting antitumor effect of rhTNF-? fusion protein mediated by matrix metalloproteinase-2.
Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies.
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA.
Targeting NF-?B mediated cell signaling pathway and inflammatory mediators by 1,2-diazole in A549 cells in vitro.
Targeting of gelatinase activity with a radiolabeled cyclic HWGF peptide.
Targeting of MMP2 activity in malignant tumors with a 68Ga-labeled gelatinase inhibitor cyclic peptide.
Targeting of tumor blood vessels: a phage-displayed tumor-homing peptide specifically binds to matrix metalloproteinase-2-processed collagen IV and blocks angiogenesis in vivo.
Targeting signaling pathways of VEGFR1 and VEGFR2 as a potential target in the treatment of breast cancer.
Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice.
Targeting the 90kDa heat shock protein improves photodynamic therapy.
Targeting the MMP-14/MMP-2/integrin ?v?3 axis with multispecific N-TIMP2-based antagonists for cancer therapy.
Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions.
Targeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer.
Targeting the tumor microenvironment with chemically modified tetracyclines: inhibition of laminin 5 gamma2 chain promigratory fragments and vasculogenic mimicry.
Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease.
Temozolomide does not influence the transcription or activity of matrix metalloproteinases 9 and 2 in glioma cell lines.
Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells.
TGF-?1 facilitates MT1-MMP-mediated proMMP-9 activation and invasion in oral squamous cell carcinoma cells.
TGF-?1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-?B/IL-6/MMP-2.
TGF-beta enhances MMP-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex.
TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system.
TGFbeta1 regulation and collagen-release-independent connective tissue re-modelling by the ruthenium complex NAMI-A in solid tumours.
Thalidomide decreases gelatinase production by malignant B lymphoid cell lines through disruption of multiple integrin-mediated signaling pathways.
Thalidomide influences growth and vasculogenic mimicry channel formation in melanoma.
The a3 Isoform Vacuolar Type H+-ATPase Promotes Distant Metastasis in the Mouse B16 Melanoma Cells.
The absence of immunoreactivity for tissue inhibitor of metalloproteinase-1 (TIMP-1), but not for TIMP-2, protein is associated with a favorable prognosis in aggressive breast carcinoma.
The activation of TLR7 regulates the expression of VEGF, TIMP1, MMP2, IL-6, and IL-15 in Hela cells.
The activity of matrix metalloproteinases (MMPS) and tissue inhibitors of metalloproteinases (TIMPs) in mammary tumors of dogs and rats.
The alpha 3 chain of type IV collagen prevents activation of human polymorphonuclear leukocytes.
The angiosuppressive effects of 20(R)- ginsenoside Rg3.
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases.
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
The behavior of matrix metalloproteinases and their inhibitors in colorectal cancer.
The behavior of MMP-2, MMP-7, MMP-9 and their inhibitors TIMP-1, TIMP-2 in adenoma-colorectal cancer sequence.
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
The C3G/Rap1 pathway promotes secretion of MMP-2 and MMP-9 and is involved in serous ovarian cancer metastasis.
The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts.
The CDK6-c-Jun-Sp1-MMP-2 axis as a biomarker and therapeutic target for triple-negative breast cancer.
The clinical relevance of stromal matrix metalloproteinase expression in ovarian cancer.
The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma.
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
The combined use of EphA2/MMP-2 expression and MRI findings contributes to the determination of cerebral glioma grade.
The complexity of molecular processes in osteoarthritis of the knee joint.
The correlation between immunohistochemical expression of MMP-2 and the prognosis of epithelial ovarian cancer.
The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis.
The curcumin derivative WZ35 activates ROS-dependent JNK to suppress hepatocellular carcinoma metastasis.
The Difference of Expression of 18 Genes in Axillary Invasion and Vascular Invasion Compared to Control Samples in Breast Cancer.
The distribution of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal cancer.
The effect of Candida albicans systemic infection on matrix metalloproteinases in breast cancer bearing BALB/c mice.
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats.
The effect of hypoxic microenvironment on matrix metalloproteinase expression in xenografts of human oral squamous cell carcinoma.
The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients.
The effect of PI3K inhibitor LY294002 and gemcitabine hydrochloride combined with ionizing radiation on the formation of vasculogenic mimicry of Panc-1 cells in vitro and in vivo.
The effect of platelets on invasiveness and protease production of human mammary tumor cells.
The effect of probiotic yoghurt consumption on oxidative stress and inflammatory factors in young females after exhaustive exercise.
The effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline-induced right ventricular failure.
The effect of tumor necrosis factor-alpha on human malignant glial cells.
The Effectiveness of Raloxifene-Loaded Liposomes and Cochleates in Breast Cancer Therapy.
The effects of CoQ10 supplement on matrix metalloproteinases, oxidative DNA damage and pro-inflammatory cytokines in testicular ischaemia/reperfusion injury in rats.
The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo.
The effects of high-dose vitamin E supplementation on biomarkers of kidney injury, inflammation, and oxidative stress in patients with diabetic nephropathy: A randomized, double-blind, placebo-controlled trial.
The effects of propofol on the growth behavior of hepatoma xenografts in Balb/c mice.
The EGF signaling pathway influences cell migration and the secretion of metalloproteinases by myoepithelial cells in pleomorphic adenoma.
The enzymatic processing of ?-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site.
The estimation of metaloproteinases and their inhibitors blood levels in patients with pancreatic tumors.
The ETS transcription factor MEF is a candidate tumor suppressor gene on the X chromosome.
The Evaluation of AREG, MMP-2, CHI3L1, GFAP, and OPN Serum Combined Value in Astrocytic Glioma Patients' Diagnosis and Prognosis.
The evolution of the matrix metalloproteinase inhibitor drug discovery program at abbott laboratories.
The expression and activity of MMPs are increased in residual tumor tissues after the termination of immunotherapy.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma.
The expression of apoptotic proteins and matrix metalloproteinases in odontogenic myxomas.
The expression of iNOS and nitrotyrosine in colitis and colon cancer in humans.
The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades.
The expression of matrix metalloproteinases in intrahepatic cholangiocarcinoma, hilar (Klatskin tumor), middle and distal extrahepatic cholangiocarcinoma, gallbladder cancer, and ampullary carcinoma: role of matrix metalloproteinases in tumor progression and prognosis.
The expression of metaloproteinases-2 and -9 is different according to the patterns of growth and invasion in squamous cell carcinoma of the penis.
The expression of MMP-2 and Ki-67 in head and neck melanoma, and their correlation with clinic-pathologic indices.
The expression of MMP-2 and TIMP-2 in patients with colorectal adenocarcinoma invaded to the submucosal and proper muscle layer.
The favorable prognostic impact of tissue inhibitor of matrix metalloproteinases-1 protein overexpression in breast cancer cells.
The flare-up reactions after systemic provocation in contact allergy to nickel and gold.
The Foxc2 transcription factor regulates tumor angiogenesis.
The G(12) family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion.
The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump.
The herbal medicine Sho-saiko-to inhibits growth and metastasis of malignant melanoma primarily developed in ret-transgenic mice.
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.
The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.
The In Ovo Chick Chorioallantoic Membrane (CAM) Assay as an Efficient Xenograft Model of Hepatocellular Carcinoma.
The in vitro and in vivo anti-metastatic efficacy of oxythiamine and the possible mechanisms of action.
The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis.
The inhibitory mechanism of a novel cationic glucosamine derivative against MMP-2 and MMP-9 expressions.
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer.
The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity.
The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model.
The laminin receptor and basement membrane dissolution: role in tumour metastasis.
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
The matrix metalloproteinase inhibitor batimastat (BB-94) retards human breast cancer solid tumor growth but not ascites formation in nude mice.
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis.
The metallo-disintegrin ADAM10 (MADM) from bovine kidney has type IV collagenase activity in vitro.
The Metastatic Microenvironment: Melanoma-Microglia Cross-Talk Promotes the Malignant Phenotype of Melanoma Cells.
The mir-423-5p/MMP-2 Axis Regulates the Nerve Growth Factor-Induced Promotion of Chondrosarcoma Metastasis.
The MMP-2 -735 C allele is a risk factor for susceptibility to breast cancer.
The MMP-2 and MMP-9 promoter polymorphisms and susceptibility to salivary gland cancer.
The molecular mechanisms of celecoxib in tumor development.
The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer.
The multifunctional role of the immunohistochemical expression of MMP-7 in invasive breast cancer.
The MyD88 inhibitor TJ-M2010-2 suppresses proliferation, migration and invasion of breast cancer cells by regulating MyD88/GSK-3? and MyD88/NF-?B signalling pathways.
The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation.
The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.
The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway.
The preventive and curative effects of melatonin against abdominal aortic aneurysm in rats.
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.
The prognostic value of CXCR4, MMP-2 and MMP-9 in tongue squamous carcinoma.
The prognostic value of metalloproteinases and angiogenic factors in ovarian carcinoma.
The prognostic value of the expression of collagenase IV, cathepsin D and metallothionein in squamous cell carcinomas of the skin determined by immunohistochemistry.
The programmed site-specific delivery of the angiostatin sunitinib and chemotherapeutic paclitaxel for highly efficient tumor treatment.
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun.
The ratio of MMP-2 to TIMP-2 in hilar cholangiocarcinoma: a semi-quantitative study.
The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 (MMP-2) processing and tumor angiogenesis.
The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer.
The relationship between endotoxemia and hepatic endocannabinoids in cirrhotic rats with portal hypertension.
The relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis.
The relationship of metalloproteinase gene polymorphisms and lung cancer.
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
The Response of Osteoblast-Like SaOS-2 Cells to Modified Titanium Surfaces.
The role of angiocidin in sarcomas.
The role of extracellular matrix metalloproteinase inducer protein in prostate cancer progression.
The role of gelatinases in colorectal cancer progression and metastasis.
The role of inflammation in patients with intraductal mucinous neoplasm of the pancreas and in those with pancreatic adenocarcinoma.
The role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the development of esophageal cancer.
The role of matrix metalloproteinases in pathogenesis of human bladder cancer.
The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis.
The role of MMP-2 and MMP-9 as prognostic markers in the early stages of tongue squamous cell carcinoma.
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma.
The role of MT2-MMP in cancer progression.
The Role of Oxidative Stress Markers in Predicting Acute Thrombotic Occlusion of Haemodialysis Vascular Access and Progressive Stenotic Dysfunction Demanding Angioplasty.
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
The role of SDF-1/CXCR4 axis in ovarian cancer metastasis.
The role of serum response factor in hepatocellular carcinoma: An association with matrix metalloproteinase.
The role of the activated form of matrix metalloproteinase-2 in urothelial cancer.
The role of the Fas/FasL signaling pathway in environmental toxicant-induced testicular cell apoptosis: An update.
The role of the IGF-I receptor in the regulation of matrix metalloproteinases, tumor invasion and metastasis.
The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer.
The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection.
The site-dependent growth characteristics of a human xenotransplanted basaloid squamous cell carcinoma.
The Target Differences of Anti-Tumorigenesis Potential of Curcumin and its Analogues Against HER-2 Positive and Triple-Negative Breast Cancer Cells.
The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis.
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alphaVbeta3 integrin in human breast cancer cells.
The upregulated ?-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.
The use of EEM fluorescence data and OPLS/UPLS-DA algorithm to discriminate between normal and cancer cell lines: a feasibility study.
Therapeutic effect of topical 5-fluorouracil in conjunctival squamous carcinoma is associated with changes in matrix metalloproteinases and tissue inhibitor of metalloproteinases expression.
Therapeutic effects of dendrosomal solanine on a metastatic breast tumor.
Therapeutic nanomedicine based on dual-intelligent functionalized gold nanoparticles for cancer imaging and therapy in vivo.
Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases.
Therapeutic targeting of oncogenic transforming growth factor-?1 signaling by antisense oligonucleotides in oral squamous cell carcinoma.
Therapeutic targeting of the endothelin a receptor in human ovarian carcinoma.
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Thrombin-thrombomodulin activation of protein C facilitates the activation of progelatinase A.
Thrombospondin-4 promotes bladder cancer cell migration and invasion via MMP2 production.
Thrombospondins, metallo proteases and thrombospondin receptors messenger RNA and protein expression in different tumour sublines of the Dunning prostate cancer model.
Tideglusib induces apoptosis in human neuroblastoma IMR32 cells, provoking sub-G0/G1 accumulation and ROS generation.
Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer.
Tight junction protein claudin-1 enhances the invasive activity of oral squamous cell carcinoma cells by promoting cleavage of laminin-5 gamma2 chain via matrix metalloproteinase (MMP)-2 and membrane-type MMP-1.
TIMP-1 expression in anaplastic large cell lymphoma is usually restricted to macrophages and only seldom observed in tumour cells.
TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.
TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis.
TIMP-2 fusion protein with human serum albumin potentiates anti-angiogenesis-mediated inhibition of tumor growth by suppressing MMP-2 expression.
TIMP-2 gene rs4789936 polymorphism is associated with increased risk of breast cancer and poor prognosis in Southern Chinese women.
Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer.
Tissue and circulating immunoreactive protein for MMP-2 and TIMP-2 in head and neck squamous cell carcinoma-tissue immunoreactivity predicts aggressive clinical course.
Tissue and serum metalloproteinase (MMP-2) expression in advanced ovarian serous cystoadenocarcinomas: clinical and prognostic implications.
Tissue and serum mRNA profile of MMPs-2/9 as a potential novel biomarker for the most individual approach in infantile hemangiomas and cancer disease.
Tissue distribution of major matrix metalloproteinases and their transcripts in human breast carcinomas.
Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer.
Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate.
Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells.
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Tissue inhibitor of metalloproteinases-1 (TIMP-1) RNA is expressed at elevated levels in malignant non-Hodgkin's lymphomas.
Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase.
Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer.
Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma.
Tissue transglutaminase regulates MMP-2 in ovarian cancer by modulating CREB activity.
TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.
TMEFF2 inhibits pancreatic cancer cells proliferation, migration, and invasion by suppressing phosphorylation of the MAPK signaling pathway.
TNF-? inhibition decreases MMP-2 activity, reactive oxygen species formation and improves hypertensive vascular hypertrophy independent of its effects on blood pressure.
Tocilizumab inhibits interleukin-6-mediated matrix metalloproteinase-2 and -9 secretions from human amnion cells in preterm premature rupture of membranes.
Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells.
Toll-like receptor 4 mediates inflammatory cytokine secretion in smooth muscle cells induced by oxidized low-density lipoprotein.
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction.
Tomatidine inhibits cell invasion through the negative modulation of gelatinase and inactivation of p38 and ERK.
Topical application of recombinant platelet-derived growth factor increases the rate of healing and the level of proteins that regulate this response.
Towards prostate cancer gene therapy: Development of a chlorotoxin-targeted nanovector for toxic (melittin) gene delivery.
TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells.
Tranexamic acid can inhibit tongue squamous cell carcinoma invasion in vitro.
Transcription repressor slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma.
Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter.
Transcriptional expression of the genes implicated in angiogenesis and tumor invasion in cervical carcinomas.
Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma.
Transcriptional Repressor Snail and Metastasis in Hepatocellular Carcinoma.
Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma.
Transcutaneous carbon dioxide induces mitochondrial apoptosis and suppresses metastasis of oral squamous cell carcinoma in vivo.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas.
Transforming growth factor beta 1 regulation of metalloproteinase production in cultured human cervical epithelial cells.
Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.
Transforming growth factor beta1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro.
Transforming growth factor-β and matrix metalloproteinase secretion in cell culture from ex-vivo pbmc after exposure to uv radiation.
Transforming growth factor-?1 suppresses the up-regulation of matrix metalloproteinase-2 by lung fibroblasts in response to tumor necrosis factor-?.
Transforming growth factor-beta1 modulates metalloproteinase-2 and -9, nitric oxide, RhoA and alpha-smooth muscle actin expression in colon adenocarcinoma cells.
Transglutaminase-2 Is Involved in All-Trans Retinoic Acid-Induced Invasion and Matrix Metalloproteinases Expression of SH-SY5Y Neuroblastoma Cells via NF-?B Pathway.
Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue.
Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and -9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells.
Treatment with granulocyte colony-stimulating factor ameliorates chronic heart failure.
Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo.
Trichostatin A-histone deacetylase inhibitor with clinical therapeutic potential-is also a selective and potent inhibitor of gelatinase A expression.
Tricolor imaging of MMPs to investigate the promoting roles of inflammation on invasion and migration of tumor cells.
Triptolide sensitizes cisplatin-resistant human epithelial ovarian cancer by inhibiting the phosphorylation of AKT.
Tumor Cell Invasion Induced by Radiation in Balb/C Mouse is Prevented by the Cox-2 Inhibitor NS-398.
Tumor cell invasion inhibited by TIMP-2.
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2.
Tumor cell specific expression of MMP-2 correlates with tumor vascularisation in breast cancer.
Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase.
Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase.
Tumor characteristics involved in the metastatic behaviour as an improvement in primary cutaneous melanoma prognostics.
Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers.
Tumor delivery efficiency and apoptosis enhancement by EVO nanoparticles on murie hepatic carcinoma cell line H22.
Tumor detection using 18F-labeled matrix metalloproteinase-2 inhibitor.
Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate.
Tumor grade and matrix metalloproteinase 2 expression in stromal fibroblasts help to stratify the high-risk group of patients with early breast cancer identified on the basis of st gallen recommendations.
Tumor marker potential of serum matrix metalloproteinases in patients with head and neck cancer.
Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Tumor microenvironment triple-responsive nanoparticles enable enhanced tumor penetration and synergetic chemo-photodynamic therapy.
Tumor necrosis factor ?, protein gene product 9.5, matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 presence in congenital intra-abdominal adhesions in children under one year of age.
Tumor necrosis factor alpha and lymphotoxin stimulate human myeloblastic leukemia cell (ML-1) invasion through a reconstituted basement membrane (Matrigel) with concomitant induction of 92 kDa gelatinase secretion.
Tumor necrosis factor stimulates gelatinase and collagenase production by granulation tissue in culture.
Tumor necrosis factor-? regulates matrix metalloproteinase-2 expression and cell migration via ERK pathway in rat glomerular mesangial cells.
Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci.
Tumor progression and expression of matrix metalloproteinase-2 (MMP-2) mRNA by human urinary bladder cancer cells.
Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors.
Tumor promoter-stimulated Mr 92,000 gelatinase secreted by normal and malignant human cells: isolation and characterization of the enzyme from HT1080 tumor cells.
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.
Tumor targeted gold nanoparticles for FRET-based tumor imaging and light responsive on-demand drug release.
Tumor targeting and microenvironment-responsive nanoparticles for gene delivery.
Tumor targeting with a selective gelatinase inhibitor.
Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle.
Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns.
Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells.
Tumor-elicited polymorphonuclear cells, in contrast to "normal" circulating polymorphonuclear cells, stimulate invasive and metastatic potentials of rat mammary adenocarcinoma cells.
Tumor-specific urinary matrix metalloproteinase fingerprinting: identification of high molecular weight urinary matrix metalloproteinase species.
Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN.
Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling.
Tumor-targeted drug delivery and sensitization by MMP2-responsive polymeric micelles.
Tumor-targeting and microenvironment-responsive smart nanoparticles for combination therapy of antiangiogenesis and apoptosis.
Tumor-Treating Fields Inhibit the Metastatic Potential of Osteosarcoma Cells.
Tumor-Triggered Disassembly of a Multiple-Agent-Therapy Probe for Efficient Cellular Internalization.
Tumor-triggered transformation of chimeric peptide for dual-stage-amplified magnetic resonance imaging and precise photodynamic therapy.
Tumoral and macrophage uPAR and MMP-9 contribute to the invasiveness of B16 murine melanoma cells.
Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
Tumorigenic potential of extracellular matrix metalloproteinase inducer.
Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1).
Tumour necrosis factor alpha up-regulates matrix metalloproteinase-2 activity in periovulatory ovine follicles: metamorphic and endocrine implications.
Tumour Necrosis Factor-alpha and Matrix Metalloproteinase-2 are Expressed Strongly in Hidradenitis Suppurativa.
Tumour-associated fibrinolysis: the prognostic relevance of plasminogen activators uPA and tPA in human breast cancer.
Tumour-targeting properties of antibodies specific to MMP-1A, MMP-2 and MMP-3.
Two-stage activated nano-truck enhanced specific aggregation and deep delivery for synergistic tumor ablation.
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Type I collagen-induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells.
Type IV collagen induces matrix metalloproteinase 2 activation in HT1080 fibrosarcoma cells.
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue.
Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Type IV collagenase activity of a primary HSV-2-induced hamster fibrosarcoma and its in vivo metastases and in vitro clones.
Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors.
Type IV collagenase/gelatinase (MMP-2) is not increased in plasma of patients with cancer.
Type IV collagenases in tumor invasion and metastasis.
Ulex europaeus I lectin induces activation of matrix-metalloproteinase-2 in endothelial cells.
Ultraviolet radiation-induced inflammation activates ?-catenin signaling in mouse skin and skin tumors.
Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metalloprotease, and laminin 5 gamma 2 correlates with the invasiveness of human glioma.
Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells.
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Upregulation of matrix metalloproteinases (MMPs) in breast cancer xenografts: a major induction of stromal MMP-13.
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line.
Urinary release of 72 and 92 kDa gelatinases, TIMPs, N-GAL and conventional prognostic factors in urothelial carcinomas.
Urinary TIMP-1 and MMP-2 levels detect the presence of pancreatic malignancies.
Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.
Usefulness of VEGF, MMP-2, MMP-3 and TIMP-2 serum level evaluation in patients with adrenal tumours.
Using caffeoyl pyrrolidine derivative LY52, a potential inhibitor of matrix metalloproteinase-2, to suppress tumor invasion and metastasis.
Uterine cervical carcinoma: Role of matrix metalloproteinases (Review).
Values of MMP-2 and MMP-9 in Tumor Tissue of Basal-Like Breast Cancer Patients.
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Vascular endothelial growth factor activating matrix metalloproteinase in ascitic fluid during peritoneal dissemination of ovarian cancer.
Vascular endothelial growth factor expression in the basal subtype of breast carcinoma.
Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation.
Vascular endothelial growth factor stimulates organ-specific host matrix metalloproteinase-9 expression and ovarian cancer invasion.
Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor.
Vasculogenic mimicry is a major feature and novel predictor of poor prognosis in patients with orbital rhabdomyosarcoma.
Vasoactive intestinal peptide ameliorates synovial cell functions of collagen-induced arthritis rats by down-regulating NF-kappaB activity.
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis.
VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein.
VEGFR-2 kinase domain inhibition as a scaffold for anti-angiogenesis: Validation of the anti-angiogenic effects of carotenoids from Spondias mombin in DMBA model of breast carcinoma in Wistar rats.
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Verbascoside Inhibits Glioblastoma Cell Proliferation, Migration and Invasion While Promoting Apoptosis Through Upregulation of Protein Tyrosine Phosphatase SHP-1 and Inhibition of STAT3 Phosphorylation.
Vernolide-A inhibits radiation-induced hypoxia-mediated tumor angiogenesis by regulating HIF-1?, MMP-2, MMP-9, and VEGF.
Versatile Functionalization of Poly(methacrylic acid) Brushes with Series of Proteolytically Cleavable Peptides for Highly Sensitive Protease Assay.
Vicenin-2: a potential radiosensitizer of non-small cell lung cancer cells.
Video-rate bioluminescence imaging of matrix metalloproteinase-2 secreted from a migrating cell.
Vinorelbine cationic liposomes modified with wheat germ agglutinin for inhibiting tumor metastasis in treatment of brain glioma.
Violacein inhibits matrix metalloproteinase mediated CXCR4 expression: potential anti-tumor effect in cancer invasion and metastasis.
Visualization of MMP-2 Activity Using Dual-Probe Nanoparticles to Detect Potential Metastatic Cancer Cells.
Vitamin D, tamoxifen and beta-estradiol modulate breast cancer cell growth and interleukin-6 and metalloproteinase-2 production in three-dimensional co-cultures of tumor cell spheroids with endothelium.
Walker 256 cancer cells secrete tissue inhibitor of metalloproteinase-free metalloproteinase-9.
Walker 256 tumor cell degradation of extracellular matrices involves a latent gelatinase activated by reactive oxygen species.
WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression.
What structure and function of avian plasminogen activator and matrix metalloproteinase-2 reveal about their counterpart mammalian enzymes, their regulation and their role in tumor invasion.
Wnt signaling pathway inhibitors as promising diagnostic serum markers of osteolytic bone metastasis.
Worse prognosis in breast cancer patients can be predicted by immunohistochemical analysis of positive MMP-2 and negative estrogen and progesterone receptors.
Wound-healing Activity of Zanthoxylum bungeanum Maxim Seed Oil on Experimentally Burned Rats.
ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo.
Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-?1 signaling pathway.
Zinc deprivation promotes progression of 1,2-dimethylhydrazine-induced colon tumors but reduces malignant invasion in mice.
Zinc supplementation attenuates ethanol- and acetaldehyde-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS) production and by influencing intracellular signaling.
Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development.
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.
Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment.
Zoledronic-acid-induced circulating level modifications of angiogenic factors, metalloproteinases and proinflammatory cytokines in metastatic breast cancer patients.
Zymographic analysis of circulating and tissue forms of colon carcinoma gelatinase A (MMP-2) and B (MMP-9) separated by mono- and two-dimensional electrophoresis.
Zymographic detection and clinical correlations of MMP-2 and MMP-9 in breast cancer sera.
[4-acetamidophenyl retinoate (4-APR) inhibits reconstituted basement membrane invasion by tumor cells and its mechanism]
[A study on the correlation between the activity of 72,000 type IV collagenase and the metastatic potential of cancer cells]
[An experimental research on tumor metastasis treated by chicken homologous matrix metalloproteinase-2 vaccine combined with low-dose cisplatin]
[Analysis of the mechanism of trophoblast infiltration]
[Anti-human collagenase type IV expression in preneoplastic lesions and early squamous cell lung carcinoma]
[Anti-sense nucleic acid of CyclinD1 induces apoptosis of lung adenocarcinoma cancer cell A549.]
[Assay of matrix metalloproteinase levels and their endogenous inhibitors in patients with laryngeal carcinoma]
[Association of JMJD3, MMP-2 and VEGF expressions with clinicopathological features of invasive ductal breast carcinoma].
[Bcl-2 associated athanogene 3 affects the epithelial-mesenchymal transition in human cervical cancer].
[CD147 increases invasiveness of U937 cells through regulation of matrix metalloproteinase activity]
[Characteristics and in vitro imaging study of matrix metalloproteinase-2 targeting activable cell-penetrating peptide]
[Clinical and prognostic significance of tumor-associated proteases in gynecologic oncology]
[Clinical significance and relationship of expression of matrix metalloproteinase-2 mRNA with breast cancer metastasis.]
[Clinical significance of matrix metalloproteinase-2 expression in patients with epithelial ovarian tumor]
[Clinicopathological significance of expressions of RECK and MMP-2 in esophageal squamous carcinoma]
[Collagenases and cancers]
[Comparative study of mRNA expression of E-cadherin and collagenase IV in early and advanced cancers]
[Constructing the tumor cell vaccine based on homologous matrix metalloproteinase-2 and exploring its effects]
[Construction and secretory expression of single-chain Fv fragment M97 with therapeutic potential against tumor invasion and metastasis]
[Correlation between expression of matrix metalloproteinase-2 and angiogenesis in esophageal carcinoma]
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
[Correlation between expression of MMP-2, MMP-9, TIMP-2, TIMP-1 and metastasis of neuroblastoma]
[Correlation between expressions of matrix metalloproteinase-2 & 9 and vasculogenic mimicry in gastrointestinal stromal tumors]
[Correlation between matrix metalloproteinases-2 and tissue inhibitor of metalloproteinase-2 expression, metastatic potential and tumor angiogenesis in synovial sarcoma and its prognostic significance]
[Correlation between MMP-2 activation and MT1-MMP mRNA expression in thymic epithelial tumors]
[Correlation between the biological behavior and invasion potential in three mouse melanoma cell lines]
[Correlation of expression of vascular endothelial growth factor and matrix matalloproteinase-2 to invasion of ovarian tumor cells in vitro]
[Correlation of MUC1 expression to adhesion of breast cancer cell line MDA-MB-231.]
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
[Detection and activity analysis of gelatinases in bone and soft tissue tumors]
[Detection of micrometastases in sentinel lymph nodes of breast cancer]
[Effect of anticancer drugs on invasive capacity of human small-cell lung cancer cells in vitro]
[Effect of As(2)O(3) on Expressions of COX-2 and Matrix Metalloproteinases in SGC7901 and K562 Cells.]
[Effect of bone morphogenetic protein-2 on the expression of membrane Type 1-matrix metalloproteinase in human A549 lung carcinoma cells]
[Effect of cyclooxygenase-2,and matrix metalloproteinase-2 expression on prognosis of lung cancer]
[Effect of decidual cell conditioned media on invasion-related gene expression of ovarian tumor cell line COC1]
[Effect of epigallocatechin-3-gallate on the invasiveness of hepatocarcinoma cells in vitro]
[Effect of human bone marrow mesenchymal stem cells on invasion of tongue squamous cell carcinoma cell line Cal-27].
[Effect of hypoxia on production and secretion of matrix metalloproteinases in tumor cells]
[Effects of c9, t11-conjugated linoleic acid on the metastasis of human gastric carcinoma cell line]
[Effects of focal adhesional kinase signaling on TNF-? induced gelatinases activity in cornea epithelium].
[Effects of MT1-MMP on the in vitro invasiveness of breast cancer cells]
[Effects of recombinant human endostatin and docetaxel on MMP and its following anti-neoplastic effect under different administration sequences]
[Elevated expression of matrix metalloproteinase-9, and fibronectin concentration in recurrent epithelial ovarian cancer]
[Establishment and characterization of a new human renal cell carcinoma cell line (KG-2) and metastatic model in nude mice]
[Experimental study on mechanism of shugan qingzhi granule for stabilizing or reducing the plaque of atherosclerosis]
[Expression and clinical impact of vascular endothelial growth factor and matrix metalloproteinase-2 in hepatocellular carcinoma]
[Expression and clinical significance of kisspeptin-1, matrix metalloproteinase-2 and vascular endothelial growth factor in tissue of colon cancer].
[Expression and clinical significance of matrix metalloproteinase in gastric stromal tumor]
[Expression and clinical significance of MMP-2, MMP-9,TIMP-1, and TIMP-2 in breast carcinoma]
[Expression and pathological mechanism of MMP-9 and HIF-2? in CD133(+) lung cancer stem cells].
[Expression and significance of matrix metalloproteinases and their tissue inhibitors in the infiltration and metastasis of lung cancer.]
[Expression and significance of tumor necrosis factor alpha, matrix metalloproteinase 2 and collagen in skin tissue of pressure ulcer of rats].
[Expression of CD147 and MMP-2 in human gliomas and its correlations with prognosis]
[Expression of CD147, matrix metalloproteinases and transforming growth factor beta1 in breast cancer]
[Expression of FOXC-2 and YB-1 in Gastric Carcinoma and Its Role in Invasion and Metastasis].
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
[Expression of matrix metalloproteinase (MMP-2) and extracellular matrix metalloproteinases inducer (EMMPRIN) in benign and advanced breast cancer tissue samples]
[Expression of matrix metalloproteinase-2 and insulin-like growth factor-1 in gastric carcinoma and their clinicopathological significance].
[Expression of matrix metalloproteinase-2, 9 and it's tissue inhibitor-1, 2 in endometrial carcinoma]
[Expression of matrix metalloproteinase-2, 9 and their inhibitor-TIMP 1,2 in human squamous cell carcinoma of uterine cervix]
[Expression of matrix metalloproteinase-2,matrix metalloproteinase-9 and vascular endothdial growth factor in retinoblastoma and its clinical significance.]
[Expression of matrix metalloproteinases 2 and 9 and their tissue inhibitors 1 and 2 in papillary thyroid cancer: an association with the clinical, morphological and ultrastructural characteristics of a tumor].
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase in ameloblastoma]
[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in colorectal neoplasm]
[Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the hepatocellular carcinomas]
[Expression of matrix metalloproteinases in lung tissue and levels of some cytokines in bronchoalveolar lavage fluid in the obstructive emphysema rat models]
[Expression of matrix metalloproteinases in metastatic lesions of cutaneous squamous cell carcinoma]
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
[Expression of membrane-type I matrix metalloproteinase and its correlation with gelatinase A activation in cancer cell lines]
[Expression of membrane-type matrix metalloproteinase (MT-MMP) and activation of MMP-2 in lung cancer]
[Expression of MMP-2 and MMP-9 in non-small-cell lung cancer and their prognostic value.]
[Expression of MMP-2, HIF-1alpha and VEGF in Colon Adenoma and Colon Cancer.]
[Expression of MMPPs and TIMP and invasiveness in pituitary adenomas]
[Expression of nm23/NDPK, integrin, type IV collagenase and uPA in transplanted tumors with various metastatic potential in nude mice and surgical specimens]
[Expression of tumor matrix markers rebuild in laryngeal cancer depends on number of smoked cigarettes].
[Expressions of CD147 and matrix metalloproteinase-2 in breast cancer and their correlations to prognosis]
[Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance]
[Expressions of inflammatory and fibrogenic factors in perinephric and subcutaneous adipose tissues of patients with adrenocorticotropic hormone-independent Cushing's syndrome].
[Expressions of MMP-2 and COX-2 mRNA in bladder transitional cell carcinoma and their correlation]
[Expressions of vascular endothelial growth factor C and matrix metalloproteinases-2 and prognosis of non-small cell lung carcinoma.]
[Extracellular matrix of intracerebral tumors with different invasion activity]
[FABP5 promotes cell growth, invasion and metastasis in cervical cancer].
[Functions of neutrophil gelatinase-associated lipocalin in the esophageal carcinoma cell line SHEEC]
[Gelatinases A and B and their endogenous regulators in the corpus uteri in squamous cell cervical carcinoma].
[High tumorigenicity of human acute monocytic leukemic cell Line SHI-1 in nude mice and its mechanism]
[Imaging of biological character of cancer using positron emission tomography(PET)]
[Immunohistochemistry of matrix metalloproteinases in different morphologic types of the lung cancer developed in the inhabitants of the Semipalatinsk Region]
[Immunoscintigraphy of anti-type IV collagenase monoclonal antibody in nude mice bearing human lung cancer xenograft]
[Impacts of atovastatin and tinidazole on cardiac muscle inflammation factors of tumor necrosis factor-?, interleukin-1 and metalloproteinase-2 of experimental rabbits with atherosclerosis and periodontitis].
[Implication of VEGF and MMPs in hepatic metastasis of human colon cancer]
[In vivo and in vitro anti-tumor effect of Sanjie Kangliu Decoction]
[Increased cell migration of nasopharyngeal carcinoma cell lines in vitro by macrophage migration inhibitory factor]
[Increased expression of gelatinases A and B, matrilysin and TIMP-1 genes in human malignant gliomas ]
[Inhibition of human gastric cancer metastasis by ocreotide in vitro and in vivo]
[Inhibition of tumor invasion by new retinoid, 5-4A, and its mechanism of the action]
[Inhibitory effect of anti-type IV collagenase intrabody on invasiveness of human pulmonary giant cell carcinoma PG cells in vitro]
[Inhibitory effect of endoplasmic reticulum-retained anti-type IV collagenase intrabody on invasion and proliferation of cancer cell]
[Inhibitory effect of recombinant anti-angiogenic peptide of tumstatin on growth and metastasis of human ovarian cancer transplanted in nude mice]
[Inhibitory effects of matrix metalloproteinase (MMP) inhibitor LY52 on expression of MMP-2 and MMP-9 and invasive ability of human ovarian carcinoma cell line SKOV3]
[Interference of HIF-1alpha by RNA reduces the expression of matrix metalloproteinase-2 in human cervical carcinoma HeLa cells]
[Interstitial collagenase, gelatinases A and B and their endogenous inhibitors in squamous cell cervical carcinomas].
[Lentivirus media miR-1246 knockdown inhibits tumor growth and promotes apoptosis of SiHa cells].
[Matricryptins derived from non fibrillar collagens, MMP-2 and SPARC are involved in the control of angiogenesis]
[Matrix metalloproteinase 2 and 9 as the factor of head and neck tumor metastasis]
[Matrix metalloproteinase-2 and angiogenesis in gastric cancer]
[Matrix metalloproteinase-2 concentrations in squamous cell carcinoma of the head and neck and its clinical significance]
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
[Matrix metalloproteinases 2 and 9, their endogenous regulators, and angiotensin-converting enzyme in cervical squamous cell carcinoma].
[Matrix metalloproteinases and their endogenous regulators in squamous cervical carcinoma (review of the own data)].
[Matrix metalloproteinases and their tissue inhibitors in malignancies of the female genital tract]
[Mechanism of EGFR Over-expression and Mutations Leading to ?Biological Characteristics Changes of Human Lung Adenocarcinoma Cells ?through CXCR4/CXCL12 Signaling Pathway].
[Metastatic ability and type IV collagenase expression of oncogene-transformed human bronchial epithelial cells]
[Minocycline potentiates the antimetastatic effect of boanmycin]
[mRNA expression analysis of metastatic markers in clear-cell renal cell carcinoma]
[New direct assay method of type IV collagenase in tissue homogenate and biochemical role of collagenase against type I, and IV collagens to the invasion of the stomach and lung cancer]
[Over-expression of Hypoxia-inducible factor 1alpha increases invasive potency of LNCaP cells in vitro]
[Postoperative prognostic factors for carcinoma of the thoracic esophagus]
[Preparation, identification and application of monoclonal antibody against matrix metalloproteinases-2].
[Prognostic value of serum MMP-2 level in uterine cancer affected women]
[Promotion of MAG-1 on Metastasis of Lung Cancer Cells in vitro and Its Expression in Lung Cancer Tissue of 24 Cases.]
[Prospects for molecular research in urological oncology: bladder cancer]
[Proteases and breast carcinoma]
[Proteases by reactive stromal cells in cancer: an attractive therapeutic target]
[Regulation of matrix-degrading enzymes in gynecologic cancer tissues and cells]
[Relationship between biochemical parameters of cerebrospinal fluid and the course of multiple sclerosis].
[Relationship between serum matrix metalloproteinase-2 and metastasis and recurrence following radical hepatic resection in hepatocellular carcinoma]
[Relationship of the disturbed balance between matrix metalloproteinases and their tissue inhibitors and the invasion of malignant salivary gland tumours]
[RNAi-mediated Silencing of CXCR4 Inhibits the Adhesion, Invasion and Tumorigenicity of Acute Monocytic Leukemic Cell Line SHI-1].
[Role of matrix metalloproteinase-2 and components of the extracellular matrix--collagen type IV and laminin expression in detection of the invasive potential of pancreatic tumors]
[Role of matrix metalloproteinases-9, 2 and their inhibitor-TIMP-1, 2 in invasive pituitary adenomas biological behavior]
[Role of organ specific fibroblasts in metastasis of human renal cell carcinoma: regulation of type IV collagenase production from human renal cell carcinoma by organ specific fibroblasts]
[Role of siRNA mediated matrix metalloproteinase-2 gene silencing in the inhibition of invasion and growth of laryngeal cancer cells]
[Role of type IV collagenase in tumor cell invasion and effect of laminin on invasive potential in bile duct carcinoma]
[Role of type IV collagene and type IV collagenase in the invasion and metastasis of salivary adenoid cystic carcinoma]
[Role of vascular endothelial growth factor overexpression in ovarian tumor invasion and mechanism]
[Roles of serine proteases and matrix metalloproteinases in tumor invasion and angiogenesis]
[Serum level of MMP-2 in early breast cancer and its correlation with circulating tumor cells].
[Significance of activated matrix metalloproteinase 2 (MMP2) in progression of bladder transitional cell carcinoma]
[Stromal proteases in the progression of breast cancer]
[Study of matrix metalloproteinase-2 and -9 in thyroid papillary cancer]
[Study on effect of arsenic trioxide on adhesion and invasion of human hepatocarcinoma cells in vitro]
[Study on expression of matrix metalloproteinases and their inhibitors in parotid gland tumors]
[Study on post-translational processing and active forms of the novel metastasis-associated protein SNC19]
[The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas]
[The correlation between polymorphisms of matrix metalloproteinase-2 and -9 genes and colorectal cancer of Chinese patients]
[The effects of MMPs and TIMPs on the metastasis of oral squamous cell carcinoma to neck lymph nodes]
[The expression and its clinical significance of MMP-2 and MMP-9 in non-small cell lung cancer.]
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
[The expression of matrix metalloproteinases and their tissue inhibitors in pleomorphic adenoma]
[The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]
[The influence of c-Myc, Ki-67, MMP-2 and VEGF expression on the prognosis of hepatocellular carcinoma patients with tumor resection.]
[The matrix metalloproteinase in oral and oropharyngeol cancer - literature review].
[The mechanism and pulmonary-protective effects of endothelin-1 receptor antagonist in chronic obstructive pulmonary diseases rat model].
[The mechanisms of microenvironments influence on vasculogenic mimicry between introcular and subcutaneous melanoma]
[THE MODE OF CLARIFYING DIAGNOSTIC OF PROGRESSING FORMS OF OVARIAN CARCINOMA].
[The relationships between angiogenesis and matrix metalloproteinase-2, -9 in mice tumor intervened by feiyanning recipe's components].
[The Role and Mechanism of CXCR4 and Its Ligand SDF-1 in the Development of Cervical Cancer Metastasis.]
[The serum concentration of metalloproteinase 9 and 2 in non-small cell lung cancer patients]
[The utility of metalloproteinases (MMPs) and their inhibitors (TIMPs) in diagnostics of gynecological malignancies].
[Type IV collagenase activities in human colorectal cancers and its role in cancer invasion and metastasis]
[VALUE OF METALPROTEINASES OF BLOOD IN PATHOGENESIS OF EPITELIAL SKIN TUMORS AND THE POSSIBILITY OF THEIR SURGICAL CORRECTION].
[Y-27632 reduces the MMP2 and MMP9 expression in endothelial cell via inhibition of ROCK signal pathway].
[Zymography--method for quantitation of activity on gelatinase A (pro-MMP-2, 72 kDa) and gelatinase B (pro-MMP-9, 92 kDa) in serum of patients with breast cancer]
Neoplasms, Germ Cell and Embryonal
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Neoplasms, Glandular and Epithelial
Transcriptional Factors for Epithelial-Mesenchymal Transition Are Associated with Mesenchymal Differentiation in Gliosarcoma.
Neoplasms, Neuroepithelial
Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation.
Neoplasms, Squamous Cell
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
Neoplastic Cells, Circulating
Circulating tumor cells and serum levels of MMP-2, MMP-9 and VEGF as markers of the metastatic process in patients with high risk of metastatic progression.
EVALUATING MMP-2 AND TGFß-RI EXPRESSION IN CIRCULATING TUMOR CELLS OF PANCREATIC CANCER PATIENTS AND THEIR CORRELATION WITH CLINICAL EVOLUTION.
[Serum level of MMP-2 in early breast cancer and its correlation with circulating tumor cells].
Nephritis
Altered expression of matrix-related molecules in the development of chronic Thy1.1 nephritis.
Differential glomerular immunoexpression of matrix metalloproteinases MMP-2 and MMP-9 in idiopathic IgA nephropathy and Schoenlein-Henoch nephritis.
Expression of MMP-9 in mesangial cells and its changes in anti-GBM glomerulonephritis in WKY rats.
Extracellular matrix deposition and cell proliferation in a model of chronic glomerulonephritis in the rat.
Gene expression of metalloproteinases and their inhibitor in renal tissue of New Zealand black/white F1 mice.
Inhibition of matrix metalloproteinases attenuates anti-Thy1.1 nephritis.
Neutrophil gelatinase associated lipocalin is instrumental in the pathogenesis of antibody-mediated nephritis.
[Role of matrix metalloproteinases in the progression of renal lesions]
Nephritis, Hereditary
Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.
Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS).
Nephrosis
Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis.
Nephrosis, Lipoid
Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF-beta1 in patients with distinct types of primary glomerulonephritis.
Nephrotic Syndrome
Association of neutrophil gelatinase associated lipocalin and cystatin-C with kidney function in children with nephrotic syndrome.
Distinct metalloproteinase excretion patterns in focal segmental glomerulosclerosis.
Specific changes in plasma concentrations of matrix metalloproteinase-2 and -9, TIMP-1 and TGF-beta1 in patients with distinct types of primary glomerulonephritis.
Urinary levels of matrix metalloproteinases and their tissue inhibitors in nephrotic children.
Urine Neutrophil Gelatinase Associated Lipocalin to Creatinine Ratio: A Novel Index for Steroid Response in Idiopathic Nephrotic Syndrome.
Nervous System Diseases
Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.
Gelatinase inhibitors: a patent review (2011-2017).
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Neuralgia
Antihyperalgesic and Anti-inflammatory Effects of Atorvastatin in Chronic Constriction Injury-Induced Neuropathic Pain in Rats.
Biomarker Analysis of Orally Dosed, Dual Active, Matrix Metalloproteinase (MMP)-2 and MMP-9 Inhibitor, AQU-118, in the Spinal Nerve Ligation (SNL) Rat Model of Neuropathic Pain.
Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain.
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain.
DNMT3b SUMOylation Mediated MMP-2 Upregulation Contribute to Paclitaxel Induced Neuropathic Pain.
Effect of a Novel, Orally Active Matrix Metalloproteinase-2 and -9 Inhibitor in Spinal and Trigeminal Rat Models of Neuropathic Pain.
Folic Acid Modulates Matrix Metalloproteinase-2 Expression, Alleviates Neuropathic Pain, and Improves Functional Recovery in Spinal Cord-Injured Rats.
Intrathecal CGS-26303 Pretreatment Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain in the Spinal Cord.
Matrix metalloprotease regulation of neuropathic pain.
N-acetyl-cysteine attenuates neuropathic pain by suppressing matrix metalloproteinases.
Paeoniflorin attenuates postoperative pain by suppressing Matrix Metalloproteinase-9/2 in mice.
Pretreatment with resveratrol ameliorate trigeminal neuralgia by suppressing matrix metalloproteinase-9/2 in trigeminal ganglion.
Procyanidins attenuate neuropathic pain by suppressing matrix metalloproteinase-9/2.
Role of Matrix Metalloproteinases and Therapeutic Benefits of Their Inhibition in Spinal Cord Injury.
Neurilemmoma
Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression.
Nuclear localization of catalytically active MMP-2 in endothelial cells and neurons.
Tumor invasion-inhibiting factor 2: primary structure and inhibitory effect on invasion in vitro and pulmonary metastasis of tumor cells.
Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation.
Neuritis
Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barré syndrome.
Neuroblastoma
Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with progression in human neuroblastoma.
Constitutively active lysophosphatidic acid receptor-1 enhances the induction of matrix metalloproteinase-2.
Determination of imbalance between MMP-2 and TIMP-2 in human neuroblastoma by reverse-transcription polymerase chain reaction and its correlation with tumor progression.
Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells.
Estrogen activates matrix metalloproteinases-2 and -9 to increase beta amyloid degradation.
Hepatocyte growth factor/c-Met signaling promotes the progression of experimental human neuroblastomas.
Immunohistochemical expression of MMP-2, MMP-9, and TIMP-2 in neuroblastoma: association with tumor progression and clinical outcome.
Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma.
KLF4 overexpression and apigenin treatment down regulated anti-apoptotic Bcl-2 proteins and matrix metalloproteinases to control growth of human malignant neuroblastoma SK-N-DZ and IMR-32 cells.
Knockdown of N-Acetylglucosaminyltransferase-II Reduces Matrix Metalloproteinase 2 Activity and Suppresses Tumorigenicity in Neuroblastoma Cell Line.
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in paediatric tumour cells. Effects of tumour cell proliferation modulators on gelatinolytic activity.
Matrix Metalloproteinase-9 and Cell Division in Neuroblastoma Cells and Bone Marrow Macrophages.
Membrane-type matrix metalloproteinase-1 expression and activation of gelatinase A as prognostic markers in advanced pediatric neuroblastoma.
miR-338-3p inhibits cell growth, invasion, and EMT process in neuroblastoma through targeting MMP-2.
Mulberry leaf extract inhibits invasive potential and downregulates hypoxia-inducible factor-1? (HIF-1?) in SK-N-BE2C neuroblastoma cells.
N-Myc and Bcl-2 coexpression induces MMP-2 secretion and activation in human neuroblastoma cells.
N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53.
Platelet activating factor inhibits the expression of matrix metalloproteinases and affects invasiveness and differentiation in a system of human neuroblastoma clones.
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
S100A4 antisense oligodeoxynucleotide suppresses invasive potential of neuroblastoma cells.
Silencing of Y-box binding protein-1 by RNA interference inhibits proliferation, invasion, and metastasis, and enhances sensitivity to cisplatin through NF-?B signaling pathway in human neuroblastoma SH-SY5Y cells.
Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma.
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment.
Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells.
The neuroprotective role of tissue inhibitor of metalloproteinase-2 in MPP+- or 6-OHDA-treated SK-N-BE(2)C and SH-SY5Y human neuroblastoma cells.
The novel anti-neuroblastoma agent PF403, inhibits proliferation and invasion in vitro and in brain xenografts.
Therapeutic Efficacy of Silibinin on Human Neuroblastoma Cells: Akt and NF-?B Expressions May Play an Important Role in Silibinin-Induced Response.
Thioredoxin alters the matrix metalloproteinase/tissue inhibitors of metalloproteinase balance and stimulates human SK-N-SH neuroblastoma cell invasion.
Thymoquinone inhibits the migration of mouse neuroblastoma (Neuro-2a) cells by down-regulating MMP-2 and MMP-9.
TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.
[Correlation between expression of MMP-2, MMP-9, TIMP-2, TIMP-1 and metastasis of neuroblastoma]
Neurocysticercosis
Association of MMP-2 and MMP-9 with clinical outcome of neurocysticercosis.
Neurodegenerative Diseases
Examination of Gelatinase Isoforms in Rodent Models of Acute Neurodegenerative Diseases Using Two-Dimensional Zymography.
Neuroectodermal Tumors
Matrix metalloproteinase expression in childhood medulloblastomas/primitive neuroectodermal tumors.
Significant differences in the matrix metalloproteinase expression profiles of spontaneous medulloblastomas/primitive neuroectodermal tumors as compared with their xenografted, established tumor cell line derived counterparts.
Neurofibroma
Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression.
Neuroinflammatory Diseases
Delayed administration of a matrix metalloproteinase inhibitor limits progressive brain injury after hypoxia-ischemia in the neonatal rat.
Examination of Gelatinase Isoforms in Rodent Models of Acute Neurodegenerative Diseases Using Two-Dimensional Zymography.
Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein.
Matrix metalloproteinases as therapeutic targets for stroke.
Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer's Disease.
New in vivo compatible matrix metalloproteinase (MMP)-2 and MMP-9 inhibitors.
On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation.
Paeoniflorin attenuates postoperative pain by suppressing Matrix Metalloproteinase-9/2 in mice.
Potential relevance of cerebrospinal fluid and serum levels and intrathecal synthesis of active matrix metalloproteinase-2 (MMP-2) as markers of disease remission in patients with multiple sclerosis.
Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation.
The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.
Neurologic Manifestations
Serum values of metalloproteinase-2 and metalloproteinase-9 as related to unstable plaque and inflammatory cells in patients with greater than 70% carotid artery stenosis.
Neuroma, Acoustic
Angiogenesis in vestibular schwannomas: expression of extracellular matrix factors MMP-2, MMP-9, and TIMP-1.
Association of cavernous malformation within vestibular schwannoma: immunohistochemical analysis of matrix metalloproteinase-2 and -9.
Cystic vestibular schwannomas: a possible role of matrix metalloproteinase-2 in cyst development and unfavorable surgical outcome.
Neuromyelitis Optica
Increased cerebrospinal fluid metalloproteinase-2 and interleukin-6 are associated with albumin quotient in neuromyelitis optica: Their possible role on blood-brain barrier disruption.
Neurosyphilis
Expression of matrix metalloproteinases and their tissue inhibitors in the serum and cerebrospinal fluid of patients with HIV-1 infection and syphilis or neurosyphilis.
Neutropenia
Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.
Nevus
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Coordinate expression of membrane type-matrix metalloproteinases-2 and 3 (MT2-MMP and MT3-MMP) and matrix metalloproteinase-2 (MMP-2) in primary and metastatic melanoma cells.
Expression of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of MMP (TIMP)-1 in conjunctival melanomas and clinical implications.
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
Loss of dipeptidyl peptidase IV immunostaining discriminates malignant melanomas from deep penetrating nevi.
MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light.
PKC and PKA phosphorylation affect the subcellular localization of claudin-1 in melanoma cells.
The 'Abtropfung phenomenon' revisited: Dermal nevus cells from congenital nevi cannot activate matrix metalloproteinase 2 (MMP-2).
Nevus, Pigmented
Active and inactive forms of matrix metalloproteinases 2 and 9 in cutaneous melanoma.
Immunohistochemical expression of matrix metalloproteinase-2 and -9 in melanocytic nevi is altered by ultraviolet B.
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions.
MMP-2, TIMP-2 and MT1-MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB-light.
Non-alcoholic Fatty Liver Disease
Animal Models of Steatosis (NAFLD) and Steatohepatitis (NASH) Exhibit Hepatic Lobe-Specific Gelatinases Activity and Oxidative Stress.
Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients.
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Peripheral Blood Leukocytes and Plasma of Children with Nonalcoholic Fatty Liver Disease.
Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study.
Pioglitazone suppresses inflammation and fibrosis in nonalcoholic fatty liver disease by down-regulating PDGF and TIMP-2: Evidence from in vitro study.
Serum biomarkers of fibrosis and extracellular matrix remodeling in patients with nonalcoholic fatty liver disease: association with liver histology.
[Study on the interaction between matrix metalloproteinases gene polymorphism and central obesity in nonalcoholic fatty liver disease].
Obesity
A functional role of gelatinase A in the development of nutritionally induced obesity in mice.
Acute eccentric resistance exercise decreases matrix metalloproteinase activity in obese elderly women.
Adiponectin predicts MMP-2 activity independently of obesity.
Adipose tissue expression of gelatinases in mouse models of obesity.
Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice.
Decreased Collagen Type I is Associated with Increased Metalloproteinase-2 Activity and Protein Expression of Leptin in the Myocardium of Obese Rats.
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Increase in MMP-2 activity in overweight and obese women is associated with menopausal status.
Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans.
Leptin-induced matrix metalloproteinase-2 secretion is suppressed by trans-10,cis-12 conjugated linoleic acid.
Lipocalin-2 inhibits autophagy and induces insulin resistance in H9c2 cells.
Matrix Metallopeptidase 2 Gene Polymorphism is Associated with Obesity in Korean Population.
Matrix metalloproteinase-2 and -9 levels in obese patients.
Matrix Metalloproteinases and Their Role in Mechanisms Underlying Effects of Quercetin on Heart Function in Aged Zucker Diabetic Fatty Rats.
MMP-2 and MMP-9 levels in plasma are altered and associated with mortality in COVID-19 patients.
Nuclear factor-kappaB induction by visfatin in human vascular endothelial cells: its role in MMP-2/9 production and activation.
Periodontitis aggravates kidney damage in obese mice by MMP2 regulation.
Which salivary components can differentiate metabolic obesity?
Obesity, Abdominal
Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study.
[Study on the interaction between matrix metalloproteinases gene polymorphism and central obesity in nonalcoholic fatty liver disease].
Obstetric Labor Complications
The expression of matrix metalloproteinases in placental tissue depends on the severity of undifferentiated connective tissue dysplasia.
Obstetric Labor, Premature
Changes in matrix metalloproteinase (MMP)-2 and MMP-9 in the fetal amnion and chorion during gestation and at term and preterm labor.
Collagenolytic enzymes (gelatinases) and their inhibitors in human amniochorionic membrane.
Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection.
Low maternal serum matrix metalloproteinase (MMP)-2 concentrations are associated with preterm labor and fetal inflammatory response.
Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia.
Matrix metalloproteinases in the cervical mucus plug in relation to gestational age, plug compartment, and preterm labor.
Matrix metalloproteinases-2 and -9 and their endogenous tissue inhibitors in tissue remodeling after sealing of the fetal membranes in a sheep model of fetoscopic surgery.
Matrix metalloproteinases-2, -3 and tissue inhibitors of metalloproteinases -1, -2 in placentas from preterm pregnancies and their association with one carbon metabolites.
Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes.
Odontogenic Cyst, Calcifying
Hypoxia and proangiogenic proteins in human ameloblastoma.
Odontogenic Cysts
Discrimination of ameloblastomas from odontogenic keratocysts by cytokine levels and gelatinase species of the intracystic fluids.
Effects of positive pressure in odontogenic keratocysts.
Interleukin-1alpha enhances type I collagen-induced activation of matrix metalloproteinase-2 in odontogenic keratocyst fibroblasts.
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Odontogenic Tumors
Comparison of osteoclastogenesis and local invasiveness of ameloblastoma and keratocystic odontogenic tumor.
Correlation between radiographic area and immunolocation of MMP-2 and MMP-9 in unilocular radiographic lesions.
Expression of RECK and matrix metalloproteinase-2 in ameloblastoma.
Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
Presence of myofibroblasts and matrix metalloproteinase 2 in radicular cysts, dentigerous cysts, and keratocystic odontogenic tumors: a comparative immunohistochemical study.
Olfactory Nerve Injuries
Peak in matrix metaloproteinases-2 levels observed during recovery from olfactory nerve injury.
Oligodendroglioma
Adhesive and invasive features in gliomas.
Correlations of polymorphisms in matrix metalloproteinase-1, -2, and -7 promoters to susceptibility to malignant gliomas.
Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.
Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.
Opportunistic Infections
Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases.
Optic Neuritis
Association of MMP-2 (?1306 C/T) Gene Polymorphism with Predisposition to Optic Neuritis and Optic Neuritis Together with Multiple Sclerosis.
MMP-2 -1575G/A polymorphism modifies the onset of optic neuritis as a first presenting symptom in MS?
Oral Submucous Fibrosis
Expression of matrix metalloproteinases (MMP-1, MMP-2 and MMP-9) and their inhibitors (TIMP-1 and TIMP-2) in oral submucous fibrosis.
Increased tissue inhibitor of metalloproteinase-1 expression and inhibition of gelatinase A activity in buccal mucosal fibroblasts by arecoline as possible mechanisms for oral submucous fibrosis.
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Osteoarthritis
Association of (-1,607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms).
Basic calcium phosphate crystals induce synthesis and secretion of 92 kDa gelatinase (gelatinase B/matrix metalloprotease 9) in human fibroblasts.
Biomarkers for identifying the early phases of osteoarthritis secondary to medial patellar luxation in dogs.
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes.
Clinical Correlation with the PA/Plasmin System in Septic Arthritis of the Knee.
Differential regulation of gelatinases by transforming growth factor beta-1 in normal equine chondrocytes.
Effects of treatment with polysulfated glycosaminoglycan on serum cartilage oligomeric matrix protein and C-reactive protein concentrations, serum matrix metalloproteinase-2 and -9 activities, and lameness in dogs with osteoarthritis.
Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2.
Evaluation of serum MMP-2 and MMP-3, synovial fluid IL-8, MCP-1, and KC concentrations as biomarkers of stifle osteoarthritis associated with naturally occurring cranial cruciate ligament rupture in dogs.
High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis.
Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis.
Matrix metalloproteinase (MMP)-2, MMP-9 and MMP-13 are activated by Activated Protein C (APC) in human osteoarthritic cartilage chondrocytes.
Matrix metalloproteinase and tissue inhibitor of metalloproteinase in serum and synovial fluid of osteoarthritic dogs.
Matrix metalloproteinase-2 in synovial lavage fluid of patients with disorders of the temporomandibular joint.
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro.
Recent findings on the role of gelatinases (matrix metalloproteinase-2 and -9) in osteoarthritis.
Regulation of 2-deoxy-D-glucose transport, lactate metabolism, and MMP-2 secretion by the hypoxia mimetic cobalt chloride in articular chondrocytes.
Regulation of gelatinases expression by cytokines, endotoxin, and pharmacological agents in the human osteoarthritic knee.
Resistance training decreases matrix metalloproteinase-2 activity in quadriceps tendon in a rat model of osteoarthritis.
Serum TGF-beta2 and TGF-beta3 are increased and positively correlated to pain, functionality, and radiographic staging in osteoarthritis.
Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor.
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.
Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice.
Sustained and distinctive patterns of gene activation in synovial fibroblasts and whole synovial tissue obtained from inflammatory synovitis.
Synovial matrix metalloproteinase-2 in different stages of sheep temporomandibular joint osteoarthrosis.
Upregulation of urokinase-type plasminogen activator and inhibitor and gelatinase expression via 3 mitogen-activated protein kinases and PI3K pathways during the early development of osteoarthritis.
Urokinase-type plasminogen activator, receptor, and inhibitor correlating with gelatinase-B (MMP-9) contribute to inflammation in gouty arthritis of the knee.
Osteoarthritis, Knee
Association of (-1,607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms).
Effect of low intensity pulsed ultrasound on expression of TIMP-2 in serum and expression of mmp-13 in articular cartilage of rabbits with knee osteoarthritis.
Preventive administration of juanbi capsules for knee osteoarthritis: effects on serum MMP-2 and MMP-9 levels and cartilage repair.
TIMP-2 SNPs rs7342880 and rs4789936 are linked to risk of knee osteoarthritis in the Chinese Han Population.
Osteochondrodysplasias
Expression of Genes Encoding Extracellular Matrix Macromolecules and Metalloproteinases in Avian Tibial Dyschondroplasia.
Osteolysis
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism.
Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy.
Characterization of Normal Murine Carpal Bone Development Prompts Re-Evaluation of Pathologic Osteolysis as the Cause of Human Carpal-Tarsal Osteolysis Disorders.
Clinical and radiographic findings in two brothers affected with a novel mutation in matrix metalloproteinase 2 gene.
Genetic susceptibility to aseptic loosening following total hip arthroplasty: a systematic review.
Histologic and biochemical differences between osteolytic and nonosteolytic membranes around femoral components of an uncemented total hip arthroplasty.
Immunolocalization of MMP 2, 9 and 13 in prednisolone induced osteoporosis in mice.
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor.
Integrin ?v?6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2.
p38 signaling in titanium particle-induced MMP-2 secretion and activation in differentiating MC3T3-E1 cells.
Polyethylene wear particles do not induce inflammation or gelatinase (MMP-2 and MMP-9) activity in fibrous tissue interfaces of loosening total hip arthroplasties.
Possible role of matrix metalloproteinase in osteolytic intracranial meningiomas.
Torg-Winchester syndrome: lack of efficacy of pamidronate therapy.
Osteolysis, Essential
Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy.
Osteoporosis
Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy.
Dynamic expression of matrix metalloproteinases 2, 9 and 13 in ovariectomy-induced osteoporosis rats.
Immunolocalization of MMP 2, 9 and 13 in prednisolone induced osteoporosis in mice.
Relationship of circulating MMP-2, MMP-1, and TIMP-1 levels with bone biochemical markers and bone mineral density in postmenopausal Chinese women.
Relationships between serum osteoprotegerin, matrix metalloproteinase-2 levels and bone metabolism in postmenopausal women.
The interaction of MMP-2/B7-H3 in human osteoporosis.
[Relationships between circulating matrix metalloproteinase-1, -2 and metalloproteinase-1 levels and bone biochemical markers and bone mineral density in Chinese postmenopausal women]
Osteoporosis, Postmenopausal
Effects of 17beta-estradiol and progesterone on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in rat osteoblasts.
Relationships between serum osteoprotegerin, matrix metalloproteinase-2 levels and bone metabolism in postmenopausal women.
[Age-related changes serum levels of MMP-1 and MMP-2 in women: their relationship with bone biochemical markers and bone mineral density]
[Effects of Migu tablet on bone mineral density, serum matrix metalloproteinase-2 level and bone metabolic markers in postmenopausal osteoporosis]
[Relationships between circulating matrix metalloproteinase-1, -2 and metalloproteinase-1 levels and bone biochemical markers and bone mineral density in Chinese postmenopausal women]
Osteosarcoma
Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines.
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
Association of MMP-2 expression and prognosis in osteosarcoma patients.
Astrocyte elevated gene-1 (AEG-1) promotes osteosarcoma cell invasion through the JNK/c-Jun/MMP-2 pathway.
B7-H3 is Overexpressed in Patients Suffering Osteosarcoma and Associated with Tumor Aggressiveness and Metastasis.
Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways.
Colchicine induces membrane-associated activation of matrix metalloproteinase-2 in osteosarcoma cells in an S100A4-independent manner.
Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4.
Compounds isolated from Ageratum houstonianum inhibit the activity of matrix metalloproteinases (MMP-2 and MMP-9): An oncoinformatics study.
Cyr61 silencing reduces vascularization and dissemination of osteosarcoma tumors.
Delivery of inhibitor of growth 4 (ING4) gene significantly inhibits proliferation and invasion and promotes apoptosis of human osteosarcoma cells.
Depletion of alphaV integrins from osteosarcoma cells by intracellular antibody expression induces bone differentiation marker genes and suppresses gelatinase (MMP-2) synthesis.
Distribution and activity levels of matrix metalloproteinase 2 and 9 in canine and feline osteosarcoma.
Disulfiram suppresses invasive ability of osteosarcoma cells via the inhibition of MMP-2 and MMP-9 expression.
Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells.
EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-?B signaling pathway.
Effect of human osteopontin on proliferation, transmigration and expression of MMP-2 and MMP-9 in osteosarcoma cells.
Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-kappaB in human osteosarcoma.
Examination of the signal transduction pathways leading to activation of gelatinolytic activity by interleukin-1alpha and Porphyromonas gingivalis in human osteosarcoma cells.
Exogenously added GPI-anchored tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) displays enhanced and novel biological activities.
Expression of CXCR4 and MMP-2 is associated with poor prognosis in patients with osteosarcoma.
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis.
Genetic polymorphisms in MMP 2, 3 and 9 genes and the susceptibility of osteosarcoma in a Chinese Han population.
Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Increased expression of membrane-type matrix metalloproteinase-1 is correlated with poor prognosis in patients with osteosarcoma.
Inhibition of human osteosarcoma cell migration and invasion by a gene silencer, pyrrole-imidazole polyamide, targeted at the human MMP9 NF-?B binding site.
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
Involvement of MMP-2 in adriamycin resistance dependent on ERK1/2 signal pathway in human osteosarcoma MG-63 cells.
Irisin reverses the IL-6 induced epithelial-mesenchymal transition in osteosarcoma cell migration and invasion through the STAT3/Snail signaling pathway.
Ketoprofen in topical formulation decreases the matrix metalloproteinase-2 expression and pulmonary metastatic incidence in nude mice with osteosarcoma.
LINC00968 functions as an oncogene in osteosarcoma by activating the PI3K/AKT/mTOR signaling.
Long non-coding RNA lncTCF7 predicts poor prognosis and promotes tumor metastasis in osteosarcoma.
Matrix metalloproteinase 2 expression and survival of patients with osteosarcoma: a meta-analysis.
Matrix metalloproteinase-2 and -9 involvement in canine tumors.
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines.
N-?-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas.
Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma.
Nobiletin inhibits human osteosarcoma cells metastasis by blocking ERK and JNK-mediated MMPs expression.
Notoginsenoside R1 counteracts mesenchymal stem cell-evoked oncogenesis and doxorubicin resistance in osteosarcoma cells by blocking IL-6 secretion-induced JAK2/STAT3 signaling.
Oncogenic roles of astrocyte elevated gene-1 (AEG-1) in osteosarcoma progression and prognosis.
Overexpression of matrix metalloproteinase (MMP)-9 correlates with metastatic potency of spontaneous and 4-hydroxyaminoquinoline 1-oxide (4-HAQO)-induced transplantable osteosarcomas in rats.
Parathyroid hormone regulation of matrix degrading enzymes in rat osteoblastic osteosarcoma 17/2.8 cells.
Pigment epithelium-derived factor upregulates collagen I and downregulates matrix metalloproteinase 2 in osteosarcoma cells, and colocalises to collagen I and heat shock protein 47 in fetal and adult bone.
Polydatin enhances the chemosensitivity of osteosarcoma cells to paclitaxel.
Polyoma virus-induced osteosarcomas in inbred strains of mice: host determinants of metastasis.
Ras activation mediates WISP-1-induced increases in cell motility and matrix metalloproteinase expression in human osteosarcoma.
Risedronate inhibits human osteosarcoma cell invasion.
Role of MMP-9 and its tissue inhibitor TIMP-1 in human osteosarcoma: findings in 42 patients followed for 1-16 years.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
RUNX2 RNA interference inhibits the invasion of osteosarcoma.
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells.
Selaginella tamariscina (Beauv.) possesses antimetastatic effects on human osteosarcoma cells by decreasing MMP-2 and MMP-9 secretions via p38 and Akt signaling pathways.
Silibinin suppresses human osteosarcoma MG-63 cell invasion by inhibiting the ERK-dependent c-Jun/AP-1 induction of MMP-2.
Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells.
Statin-induced inhibition of 3-hydroxy-3-methyl glutaryl coenzyme a reductase sensitizes human osteosarcoma cells to anticancer drugs.
Target-activated transcription for the amplified sensing of protease biomarkers.
The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells.
The study of mechanism of miR-34c-5p targeting FLOT2 to regulate proliferation, migration and invasion of osteosarcoma cells.
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Visfatin triggers the in vitro migration of osteosarcoma cells via activation of NF-?B/IL-6 signals.
Otitis Media
Activities of matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in idiopathic hemotympanum and otitis media with effusion.
Effect of CT manifestations of cholesteatoma on MMP-2, MMP-9 and IL-6 in the serum of patients.
Expression of matrix metalloproteinase-9 and -2 in pediatric chronic otitis media with effusion.
Matrix metalloproteinases 2 and 9 in otitis media with effusion.
Otitis Media with Effusion
Activities of matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in idiopathic hemotympanum and otitis media with effusion.
Expression of matrix metalloproteinase-9 and -2 in pediatric chronic otitis media with effusion.
Matrix metalloproteinases 2 and 9 in otitis media with effusion.
Ovarian Cysts
Difference in expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with persistent ovarian cysts.
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
Papers to appear in forthcoming issues
Study on matrix metalloproteinase 1 and 2 gene expression and NO in dairy cows with ovarian cysts.
Ovarian Diseases
Clinical significance of serum MMP-2 and MMP-7 in patients with ovarian cancer.
Ovarian Neoplasms
37-kDa laminin receptor precursor mediates GnRH-II-induced MMP-2 expression and invasiveness in ovarian cancer cells.
9-Hydroxycanthin-6-one isolated from stem bark of Ailanthus altissima induces ovarian cancer cell apoptosis and inhibits the activation of tumor-associated macrophages.
Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.
Altered expression of metastasis-associated and regulatory molecules in effusions from breast cancer patients: a novel model for tumor progression.
Anti-tumor and chemosensitization effects of Cryptotanshinone extracted from Salvia miltiorrhiza Bge. on ovarian cancer cells in vitro.
Auraptene Inhibits Migration and Invasion of Cervical and Ovarian Cancer Cells by Repression of Matrix Metalloproteinasas 2 and 9 Activity.
BAG3 increases the invasiveness of uterine corpus carcinoma cells by suppressing miR?29b and enhancing MMP2 expression.
Baicalein inhibits MMP-2 expression in human ovarian cancer cells by suppressing the p38 MAPK-dependent NF-?B signaling pathway.
Bisphenol A induces ovarian cancer cell proliferation and metastasis through estrogen receptor-? pathways.
Calcium influx modulates expression of matrix metalloproteinase-2 (72-kDa type IV collagenase, gelatinase A).
Catalpol suppresses proliferation and facilitates apoptosis of OVCAR-3 ovarian cancer cells through upregulating microRNA-200 and downregulating MMP-2 expression.
Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles.
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2.
Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity.
Clinical significance of serum MMP-2 and MMP-7 in patients with ovarian cancer.
Collagenase expression in ovarian cancer cell lines.
Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice.
Cyclooxygenase-2 functions as a downstream mediator of lysophosphatidic acid to promote aggressive behavior in ovarian carcinoma cells.
Diet-Derived Gallated Catechins Prevent TGF-?-Mediated Epithelial-Mesenchymal Transition, Cell Migration and Vasculogenic Mimicry in Chemosensitive ES-2 Ovarian Cancer Cells.
Dihydroartiminisin inhibits the growth and metastasis of epithelial ovarian cancer.
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
Enhanced immunoreactivity of TIMP-2 in the stromal compartment of tumor as a marker of favorable prognosis in ovarian cancer patients.
Enhanced in vitro invasiveness of ovarian cancer cells through up-regulation of VEGF and induction of MMP-2.
ETS-1 regulates vascular endothelial growth factor-induced matrix metalloproteinase-9 and matrix metalloproteinase-13 expression in human ovarian carcinoma cell SKOV-3.
Evaluation of Matrix Metalloproteinases, Cytokines and Their Potential Role in the Development of Ovarian Cancer.
Expression of latent matrix metalloproteinase 9 (MMP-9) predicts survival in advanced ovarian cancer.
Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary.
Expression of matrix metalloproteinases-2 and -9 by cells isolated from the peritoneal fluid of women with ovarian carcinoma.
Expression of various matrix proteases and Ets family transcriptional factors in ovarian cancer cell lines: correlation to invasive potential.
Fibroblasts stimulate human ovarian cancer cell invasion and expression of 72-kDa gelatinase A (MMP-2).
Fibronectin secretion from human peritoneal tissue induces Mr 92,000 type IV collagenase expression and invasion in ovarian cancer cell lines.
Functional role of matrix metalloproteinases in ovarian tumor cell plasticity.
Gelatinase A-immunoreactive protein in ovarian lesions- prognostic value in epithelial ovarian cancer.
Gonadotropins Induce Tumor Cell Migration and Invasion by Increasing Cyclooxygenases Expression and Prostaglandin E2 Production in Human Ovarian Cancer Cells.
High expression of tissue inhibitor of metalloproteinase-2 in serous ovarian carcinomas and the role of this expression in ovarian tumorigenesis.
Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer.
IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in ovarian cancer cells.
Immunoexpression of the PTEN protein and matrix metalloproteinase-2 in endometrial cysts, endometrioid and clear cell ovarian cancer.
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
Increased endostatin generation and decreased angiogenesis via MMP-9 by tamoxifen in hormone dependent ovarian cancer.
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer.
Increased matrix metalloproteinase-9 activity in human ovarian cancer cells cultured with conditioned medium from human peritoneal tissue.
Inhibition of matrix metalloproteinase-2 secretion and invasion by human ovarian cancer cell line SK-OV-3 with lysine, proline, arginine, ascorbic acid and green tea extract.
Knockdown of survivin contributes to antitumor activity in cisplatin-resistant ovarian cancer cells.
Lewis (y) Antigen Overexpression Increases the Expression of MMP-2 and MMP-9 and Invasion of Human Ovarian Cancer Cells.
Limited independent prognostic value of MMP-14 and MMP-2 expression in ovarian cancer.
LPA-induced epithelial ovarian cancer (EOC) in vitro invasion and migration are mediated by VEGF receptor-2 (VEGF-R2).
Lysophosphatidic acid down-regulates stress fibers and up-regulates pro-matrix metalloproteinase-2 activation in ovarian cancer cells.
Magnolol down-regulates HER2 gene expression, leading to inhibition of HER2-mediated metastatic potential in ovarian cancer cells.
Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase.
Matrix metalloproteinase-9 expression correlates with prognosis and involved in ovarian cancer cell invasion.
Matrix metalloproteinases 2, 7, and 9 and tissue inhibitor of metalloproteinases-1 in tumors and serum of patients with ovarian neoplasms.
Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.
MicroRNA-205 promotes cell invasion by repressing TCF21 in human ovarian cancer.
miR-17 inhibits ovarian cancer cell peritoneal metastasis by targeting ITGA5 and ITGB1.
Mixed lineage kinase 3 is required for matrix metalloproteinase expression and invasion in ovarian cancer cells.
MLK4? functions as a negative regulator of MAPK signaling and cell invasion.
MMP-2 functions as an early response protein in ovarian cancer metastasis.
MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy.
Notch1 Affects Chemo-resistance Through Regulating Epithelial-Mesenchymal Transition (EMT) in Epithelial Ovarian cancer cells.
Novel functions for 2-phenylbenzimidazole-5-sulphonic acid: Inhibition of ovarian cancer cell responses and tumour angiogenesis.
Ovarian carcinoma cell cultures are resistant to TGF-beta1-mediated growth inhibition despite expression of functional receptors.
Oxytocin inhibits ovarian cancer metastasis by repressing the expression of MMP-2 and VEGF.
p21-Activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients.
Pathological and prognostic significance of matrix metalloproteinase-2 expression in ovarian cancer: a meta-analysis.
Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.
Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma.
Prognostic significance of stromal metalloproteinase-2 in ovarian adenocarcinoma and its relation to carcinoma progression.
Prognostic value of MMP-2 for patients with ovarian epithelial carcinoma: a systematic review and meta-analysis.
Quercetin attenuates metastatic ability of human metastatic ovarian cancer cells via modulating multiple signaling molecules involved in cell survival, proliferation, migration and adhesion.
Relationship between the expression of VEGF signal components and matrix metalloproteinases in ovarian tumors.
Role of immunohistochemical overexpression of matrix metalloproteinases MMP-2 and MMP-11 in the prognosis of death by ovarian cancer.
Selective mediation of ovarian cancer SKOV3 cells death by pristine carbon quantum dots/Cu2O composite through targeting matrix metalloproteinases, angiogenic cytokines and cytoskeleton.
Shed membrane fragment-associated markers for endometrial and ovarian cancers.
Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers.
Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2.
TGFbeta1 stimulates the secretion of matrix metalloproteinase 2 (MMP2) and the invasive behavior in human ovarian cancer cells, which is suppressed by MMP inhibitor BB3103.
The anti-tumor effect and bioactive phytochemicals of Hedyotis diffusa willd on ovarian cancer cells.
The C3G/Rap1 pathway promotes secretion of MMP-2 and MMP-9 and is involved in serous ovarian cancer metastasis.
The expression of tumor-derived and stromal-derived matrix metalloproteinase 2 predicted prognosis of ovarian cancer.
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
The leukotriene B4 receptor-2 promotes invasiveness and metastasis of ovarian cancer cells through STAT3-dependent up-regulation of matrix metalloproteinase 2.
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer.
The role of p53 protein and MMP-2 tumor/stromal cells expression on progressive growth of ovarian neoplasms.
The role of SDF-1/CXCR4 axis in ovarian cancer metastasis.
The value of sequential serum measurements of gelatinases and tissue inhibitors during chemotherapy in ovarian cancer.
Tissue transglutaminase regulates MMP-2 in ovarian cancer by modulating CREB activity.
Tumor-associated macrophages promote invasion via Toll-like receptors signaling in patients with ovarian cancer.
Urinary MMP-2 and MMP-9 predict the presence of ovarian cancer in women with normal CA125 levels.
Vascular endothelial growth factor activating matrix metalloproteinase in ascitic fluid during peritoneal dissemination of ovarian cancer.
WFDC2 contributes to epithelial-mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression.
[Assessment of prognostic factors in common ovarian tumors of varying malignancy]
[Association of SNPs in the promoter of MMP-2 and TIMP-2 genes with epithelial ovarian cancer]
[Correlation of vasculogenic mimicry with clinicopathologic features and prognosis of ovarian carcinoma]
[Elevated expression of matrix metalloproteinase-9, and fibronectin concentration in recurrent epithelial ovarian cancer]
[Expression of matrix metaloproteinase and tissue inhibitors in ovarian tumors]
[Fibronectin induces matrix metalloproteinase-2 expression in ovarian cancer cells]
[Preliminary study of dihydroartemisin in inhibiting invasion and metastasis of hepatoma cells].
[Preparation, identification and application of monoclonal antibody against matrix metalloproteinases-2].
Overweight
Adipocytes contribute to the growth and progression of multiple myeloma: Unraveling obesity related differences in adipocyte signaling.
Increase in MMP-2 activity in overweight and obese women is associated with menopausal status.
Pancreatic Neoplasms
?-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells.
?2-AR-HIF-1?: a novel regulatory axis for stress-induced pancreatic tumor growth and angiogenesis.
Action of antiproteases on pancreatic cancer cells.
An MMP-2 Responsive Liposome Integrating Antifibrosis and Chemotherapeutic Drugs for Enhanced Drug Perfusion and Efficacy in Pancreatic Cancer.
Antiangiogenic effect of somatostatin receptor subtype 2 on pancreatic cancer cell line: Inhibition of vascular endothelial growth factor and matrix metalloproteinase-2 expression in vitro.
Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms.
Antitumor effect of a new selective matrix metalloproteinase inhibitor, MMI-166, on experimental pancreatic cancer.
BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK.
Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2.
Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA.
Chlorotoxin-Fc fusion inhibits release of MMP-2 from pancreatic cancer cells.
Comprehensively enhanced delivery cascade by transformable beaded nanofibrils for pancreatic cancer therapy.
Correlation between B7-H3 expression and matrix metalloproteinases 2 expression in pancreatic cancer.
Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis.
Corrigendum: The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis, Journal of Physiology and Pharmacology 2020 Oct; 71(5): 689.
Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-?B pathway.
CXCL14 expression and potential function in pancreatic cancer.
Detection of matrix metalloproteinase activity in human pancreatic cancer.
Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels.
Downregulation of miR-21 inhibits the malignant phenotype of pancreatic cancer cells by targeting VHL.
Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro.
EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2.
Epithelial MMP-2 expression correlates with worse prognosis in pancreatic cancer.
EVALUATING MMP-2 AND TGFß-RI EXPRESSION IN CIRCULATING TUMOR CELLS OF PANCREATIC CANCER PATIENTS AND THEIR CORRELATION WITH CLINICAL EVOLUTION.
Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer.
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Expression of matrix metalloproteinases 1 and 2 genes in a possible association with metastatic abilities of human pancreatic cancer cells.
Expression of Matrix Metalloproteinases-2/-9 is Associated With Microvessel Density in Pancreatic Cancer.
Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells.
Extraction of type IV collagenase/gelatinase from plasma membranes of human pancreatic cancer cells.
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE?cadherin/EphA2/MMP9/MMP2 expression.
Glucose transporter-1 gene expression is associated with pancreatic cancer invasiveness and MMP-2 activity.
GSK3? mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway.
HIF1 Contributes to Hypoxia-Induced Pancreatic Cancer Cells Invasion via Promoting QSOX1 Expression.
Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer.
Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2.
In vitro and in vivo matrix metalloproteinase production by pancreatic cancer cells and by distant organs.
Induction of pancreatic cancer cell apoptosis, invasion, migration, and enhancement of chemotherapy sensitivity of gemcitabine, 5-FU, and oxaliplatin by hnRNP A2/B1 siRNA.
Inhibition and mechanism of action of a protease inhibitor in human pancreatic cancer cells.
Interaction between cancer cells and stromal fibroblasts is required for activation of the uPAR-uPA-MMP-2 cascade in pancreatic cancer metastasis.
Investigation of juglone effects on metastasis and angiogenesis in pancreatic cancer cells.
Involvement of ephrin receptor A4 in pancreatic cancer cell motility and invasion.
KAI1 is a potential target for anti-metastasis in pancreatic cancer cells.
Matrine inhibiting pancreatic cells epithelial-mesenchymal transition and invasion through ROS/NF-?B/MMPs pathway.
Matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor 2 (TIMP-2) in pancreatic cancer (PC).
Matrix metalloproteinase inhibition suppresses MMP-2 activity and activation of PANC-1 cells in vitro.
Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.
Matrix metalloproteinase-14 is a mechanically regulated activator of secreted MMPs and invasion.
Matrix metalloproteinase-2 in pancreatic juice for diagnosis of pancreatic cancer.
Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trials.
miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases.
MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancer.
Nerve growth factor stimulates MMP-2 expression and activity and increases invasion by human pancreatic cancer cells.
NRAGE suppresses metastasis of melanoma and pancreatic cancer in vitro and in vivo.
Overexpression and biological function of MEF2D in human pancreatic cancer.
Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway.
Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer.
p202, an interferon-inducible protein, mediates multiple antitumor activities in human pancreatic cancer xenograft models.
Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay.
Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells.
Peroxisome proliferator-activated receptor-? inhibits pancreatic cancer cell invasion and metastasis via regulating MMP-2 expression through PTEN.
PHGDH is an independent prognosis marker and contributes cell proliferation, migration and invasion in human pancreatic cancer.
Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells.
Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients.
Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2.
Protease-activated receptor 2 agonist increases cell proliferation and invasion of human pancreatic cancer cells.
Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression.
Ratiometric Activatable Cell-Penetrating Peptides Label Pancreatic Cancer, Enabling Fluorescence-Guided Surgery, Which Reduces Metastases and Recurrence in Orthotopic Mouse Models.
RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis.
Reduction of in vivo tumor growth by MMI-166, a selective matrix metalloproteinase inhibitor, through inhibition of tumor angiogenesis in squamous cell carcinoma cell lines of head and neck.
Role of fibrillar Tenascin-C in metastatic pancreatic cancer.
Role of MT-MMPs and MMP-2 in pancreatic cancer progression.
SDF-1? upregulation of MMP-2 is mediated by p38 MAPK signaling in pancreatic cancer cell lines.
Selection of peptide inhibitor to matrix metalloproteinase-2 using phage display and its effects on pancreatic cancer cell lines PANC-1 and CFPAC-1.
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion.
TGF-?1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-?B/IL-6/MMP-2.
TGF-beta-induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system.
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivo.
TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis.
TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo.
Transcriptomic Analyses and Potential Therapeutic Targets of Pancreatic Cancer With Concomitant Diabetes.
Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of ?-catenin.
Two-dimensional zymography for analysis of proteolytic enzymes in human pure pancreatic juice.
Ukrain Affects Pancreas Cancer Cell Phenotype in vitro by Targeting MMP-9 and Intra-/Extracellular SPARC Expression.
Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the ?-catenin pathway.
ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts.
[Effect of hypoxia on production and secretion of matrix metalloproteinases in tumor cells]
[Effect of RNAi-mediated STAT3 gene inhibition on metastasis of human pancreatic cancer cells]
[Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro]
[The mechanism of KAI1 gene in inhibition of metastasis of primary pancreatic cancer]
Pancreatitis
Associations of MMP-2 and MMP-9 gene polymorphism with ulinastatin efficacy in patients with severe acute pancreatitis.
Editorial: Acute pancreatitis and neutrophil gelatinase MMP9: don't get me started!
Hypertonic Saline Reduces Metalloproteinase Expression In Liver During Pancreatitis.
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis.
Increased matrix metalloproteinase expression and activation following experimental acute pancreatitis.
Long-term overexpression of membrane type-1 matrix metalloproteinase and matrix metalloproteinase-2 in oleic acid-induced pancreatitis in rats.
MMP-2 and MMP-9 gene polymorphisms act as biological indicators for ulinastatin efficacy in patients with severe acute pancreatitis.
Persistent destruction of the basement membrane of the pancreatic duct contributes to progressive acinar atrophy in rats with experimentally induced pancreatitis.
Role of TGF-beta1, extracellular matrix, and matrix metalloproteinase in the healing process of the pancreas after induction of acute necrotizing pancreatitis using arginine in rats.
The influence of transforming growth factor beta 1 on the expression of genes coding for matrix metalloproteinases and tissue inhibitors of metalloproteinases during regeneration from cerulein-induced pancreatitis.
Pancreatitis, Chronic
Balance of expression of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in chronic pancreatitis.
Corrigendum: The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis, Journal of Physiology and Pharmacology 2020 Oct; 71(5): 689.
Differences in Pancreatic Immunohistochemical Staining Profiles of TGF-beta1, MMP-2, and TIMP-2 Between Autoimmune and Alcoholic Chronic Pancreatitis.
Differential Diagnosis of Autoimmune Pancreatitis From Pancreatic Cancer by Analysis of Serum Gelatinase Levels.
Immunohistochemical study of transforming growth factor-beta 1, matrix metalloproteinase-2,9, tissue inhibitors of metalloproteinase-1,2, and basement membrane components at pancreatic ducts in chronic pancreatitis.
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma.
Matrix metalloproteinase-2 in pancreatic juice for diagnosis of pancreatic cancer.
Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients.
Role of MMP-2 and MMP-9 and their natural inhibitors in liver fibrosis, chronic pancreatitis and non-specific inflammatory bowel diseases.
The assessment of serum and diagnostic peritoneal lavage concentration of matrix metalloproteinase-2, matrix metalloproteinase-9, carbohydrate antigen 19-9, and carcinoembryonic antigen in patients with pancreatic cancer and chronic pancreatitis.
[Fibrosis markers in heavy alcohol drinkers]
Papilloma
Expression of matrix metalloproteinases (MMP-2 and MMP-9) in recurrent respiratory papillomas and laryngeal carcinoma: clinical and morphological parallels.
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Immunohistochemical study on the expression of matrix metalloproteinase 2 and high-risk human papilloma virus in the malignant progression of papillomas.
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Paracrine communication between malignant and non-malignant prostate epithelial cells in culture alters growth rate, matrix protease secretion and in vitro invasion.
The expression of epidermal growth factor receptor, vascular endothelial growth factor, matrix metalloproteinase-2, and cyclooxygenase-2 in relation to human papilloma viral load and persistence of human papillomavirus after conization with negative margins.
Papilloma, Inverted
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Matrix metalloproteinase-2 and -9 expression in sinonasal inverted papilloma.
Papillomavirus Infections
Matrix metalloproteinase-2, squamous cell carcinoma antigen, and tissue polypeptide-specific antigen expression in Egyptian patients with cervical carcinoma: Relationship with prognosis.
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
Paracoccidioidomycosis
Matrix metalloproteinases with gelatinolytic activity induced by Paracoccidioides brasiliensis infection.
Paralysis
HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats.
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Paraparesis, Spastic
Selective matrix metalloproteinase inhibitor, N-biphenyl sulfonyl phenylalanine hydroxamic acid, inhibits the migration of CD4+ T lymphocytes in patients with HTLV-I-associated myelopathy.
Paraparesis, Tropical Spastic
Expression of metalloproteinase-2 (gelatinase A) in labial salivary glands of patients with Sjögren's syndrome with HTLV-I infection.
Selective matrix metalloproteinase inhibitor, N-biphenyl sulfonyl phenylalanine hydroxamic acid, inhibits the migration of CD4+ T lymphocytes in patients with HTLV-I-associated myelopathy.
Vascular cell adhesion molecule-1-mediated matrix metalloproteinase-2 induction in peripheral blood T cells is up-regulated in patients with HTLV-I-associated myelopathy.
Paraproteinemias
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Parapsoriasis
Matrix metalloproteinase-2 promoter genotype as a marker of cutaneous T-cell lymphoma early stage.
Parathyroid Neoplasms
Expression of matrix metalloproteinase gelatinase A messenger ribonucleic acid in parathyroid carcinomas.
Parkinson Disease
Expression of MMP-2, MMP-9, and MMP-1 and their endogenous counterregulators TIMP-1 and TIMP-2 in postmortem brain tissue of Parkinson's disease.
Parotitis
Decreased salivary matrix metalloproteinase-8 reflecting a defensive potential in juvenile parotitis.
Pediatric Obesity
Effect of metabolic syndrome risk factors and MMP-2 genetic variations on circulating MMP-2 levels in childhood obesity.
Pelvic Inflammatory Disease
Significant elevation and correlation of plasma neutrophil gelatinase associated lipocalin and its complex with matrix metalloproteinase-9 in patients with pelvic inflammatory disease.
Significant elevation of plasma matrix metalloproteinase-9 level and its ratio to matrix metalloproteinase-2 in patients with pelvic inflammatory disease.
Pemphigoid, Benign Mucous Membrane
Neutrophil Collagenase, Gelatinase, and Myeloperoxidase in Tears of Patients with Stevens-Johnson Syndrome and Ocular Cicatricial Pemphigoid.
Pemphigoid, Bullous
92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen.
Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid.
Increased expression of matrix metalloproteinase-2, matrix metalloproteinase-9 and matrix metalloproteinase-13 in lesional skin of bullous pemphigoid.
Penile Neoplasms
E-cadherin, MMP-2, and MMP-9 as prognostic markers in penile cancer: Analysis of 125 patients.
Peri-Implantitis
LOX-1 is involved in IL-1? production and extracellular matrix breakdown in dental peri-implantitis.
Microbiological Profile and Human Immune Response Associated with Peri-Implantitis: A Systematic Review.
Periapical Abscess
The zymographic evaluation of gelatinase (MMP-2 and -9) levels in acute and chronic periapical abscesses.
Periapical Diseases
Sonic extracts from a bacterium related to periapical disease activate gelatinase A and inactivate tissue inhibitor of metalloproteinases TIMP-1 and TIMP-2.
Periapical Granuloma
Gene-expression analysis of matrix metalloproteinases 1 and 2 and their tissue inhibitors in chronic periapical inflammatory lesions.
Metalloproteinases 2 and 9 Immunoexpression in Periapical Lesions from Primary Endodontic Infection: Possible Relationship with the Histopathological Diagnosis and the Presence of Pain.
Periapical Periodontitis
Decreased levels of matrix metalloproteinase-2 in root-canal exudates during root canal treatment.
Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases during Apical Periodontitis Development.
Immunolocalization of matrix metalloproteinases-2 and -9 during apical periodontitis development.
Resveratrol Suppresses Matrix Metalloproteinase-2 Activation Induced by Lipopolysaccharide in Mouse Osteoblasts via Interactions with AMP-Activated Protein Kinase and Suppressor of Cytokine Signaling 1.
The virulence factor GroEL promotes gelatinase secretion from cells in the osteoblast lineage: Implication for direct crosstalk between bacteria and adult cells.
Pericardial Effusion
Lesions of the pericardium and their significance in the aetiology of heart failure in broiler chickens.
Periodontal Attachment Loss
Collagenolytic enzymes in gingival crevicular fluid as diagnostic indicators of periodontitis.
Host enzymes in gingival crevicular fluid as diagnostic indicators of periodontitis.
Periodontal Diseases
Analysis of in situ protease activity in chronic adult periodontitis patients: expression of activated MMP-2 and a 40 kDa serine protease.
Circulating matrix metalloproteinase-8 (MMP-8) and MMP-9 are increased in chronic periodontal disease and decrease after non-surgical periodontal therapy.
Effects of therapy with two combinations of antibiotics on the imbalance of MMP-2÷TIMP-2 in chronic periodontitis.
Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis.
Gingival crevicular fluid gelatinase and its relationship to periodontal disease in human subjects.
Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: correlation with periodontal disease activity in adult and juvenile periodontitis.
Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients.
Local and systemic factors in periodontal disease increase matrix-degrading enzyme activities in rat gingiva: effect of micocycline therapy.
Matrix metalloproteinases in periodontal tissue remodelling.
MMP-2 activation by Actinobacillus actinomycetemcomitans supernatant in human PDL cells was corresponded with reduction of TIMP-2.
Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1?, IL-10, RANK, OPG, MMP-2, TGF-? and TNF-?: follow-up over 5 years.
Suppressive effect of ethanolic Kaempferia pandurata Roxb. extract on matrix metalloproteinase-2 expression in Porphyromonas gingivalis-treated human gingival fibroblasts in vitro.
The influence of type I diabetes mellitus on the expression and activity of gelatinases (matrix metalloproteinases-2 and -9) in induced periodontal disease.
Up-regulation of osteolytic mediators in human osteosarcoma cells stimulated with nicotine.
Periodontitis
Altered gene expression in leukocyte transendothelial migration and cell communication pathways in periodontitis-affected gingival tissues.
Analysis of matrix metalloproteinase (MMP-8 and MMP-2) activity in gingival crevicular fluid from children with Down's syndrome.
Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol.
Assessment of the involvement of the macrophage migration inhibitory factor-glucocorticoid regulatory dyad in the expression of matrix metalloproteinase-2 during periodontitis.
Association of Common Variants in MMPs with Periodontitis Risk.
Association of MMP-2-753C>T and MMP-9-1562C>T Polymorphisms with Chronic/Aggressive Periodontitis Risk: A Systematic Review and Meta-Analysis.
Azilsartan increases levels of IL-10, down-regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and up-regulates OPG in an experimental periodontitis model.
Biomarkers of periodontitis in oral fluids.
Carvedilol decrease IL-1? and TNF-?, inhibits MMP-2, MMP-9, COX-2, and RANKL expression, and up-regulates OPG in a rat model of periodontitis.
Collagenolytic fragments and active gelatinase complexes in periodontitis.
Detection of Enterococcus faecalis in subgingival biofilms of healthy, gingivitis, and chronic periodontitis subjects.
Effect of microbial siderophores on matrix metalloproteinase-2 activity.
Effect of telmisartan on levels of IL-1, TNF-?, down-regulated COX-2, MMP-2, MMP-9 and RANKL/RANK in an experimental periodontitis model.
Efficacy test of horse chestnut leaf extract (ALH-L1005) as matrix metalloproteinase inhibitors in ligature-induced periodontitis in canine model.
EVALUATION OF BONE RESORPTIVE POTENTIAL IN THE TREATMENT OF GENERALIZED PERIODONTITIS.
Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in healthy and diseased human gingiva.
Expression of matrix metalloproteinases-2, -9 and reversion-inducing cysteine-rich protein with Kazal motifs in gingiva in periodontal health and disease.
Gelatinases and extracellular matrix metalloproteinase inducer are associated with cyclosporin-A-induced attenuation of periodontal degradation in rats.
Genetic Factors and the Risk of Periodontitis Development: Findings from a Systematic Review Composed of 13 Studies of Meta-Analysis with 71,531 Participants.
Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis.
Interaction between the Wnt/?-catenin signaling pathway and the EMMPRIN/MMP-2, 9 route in periodontitis.
Levels of metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-1 in gingival crevicular fluid of patients with periodontitis, gingivitis, and healthy gingiva.
Loss of alveolar bone density in postmenopausal, osteopenic women is associated with circulating levels of gelatinases.
Matrix metalloproteinase-2 may be involved with increased bone loss associated with experimental periodontitis and smoking: a study in rats.
Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients.
Matrix metalloproteinases (MMP-2 and MMP-9) of the oral cavity: cellular origin and relationship to periodontal status.
Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients.
Matrix metalloproteinases and their inhibitors in gingival mast cells in persons with and without human immunodeficiency virus infection.
Membrane type (MT) 1-matrix metalloproteinase (MMP) and MMP-2 expression in ligature-induced periodontitis in the rat.
MMP-2 salivary activity in type 2 diabetes mellitus patients.
MMP-2, MMP-9 and TIMP-2 gene polymorphisms in Chinese patients with generalized aggressive periodontitis.
Multiple forms of gelatinases/type IV collagenases in saliva and gingival crevicular fluid of periodontitis patients.
Olmesartan decreases IL-1? and TNF-? levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis.
Parathyroid hormone administration may modulate periodontal tissue levels of interleukin-6, matrix metalloproteinase-2 and matrix metalloproteinase-9 in experimental periodontitis.
Periodontal Condition and Immunological Aspects of Individuals Hospitalized in the Intensive Care Unit.
Periodontitis aggravates kidney damage in obese mice by MMP2 regulation.
Periodontitis and Endothelial Dysfunction: Periodontal Clinical Parameters and Levels of Salivary Markers Interleukin-1?, Tumor Necrosis Factor-?, Matrix Metalloproteinase-2, Tissue Inhibitor of Metalloproteinases-2 Complex, and Nitric Oxide.
Proteinase-activated receptor-2 (PAR2) agonist causes periodontitis in rats.
Proteolytic enzymes as indicators of periodontal health in gingival crevicular fluid of patients with Sjögren's syndrome.
The role of extracellular matrix metalloproteinase inducer glycosylation in regulating matrix metalloproteinases in periodontitis.
[Expression of MMP-2 and MMP-3 in periodontal tissues of rat periodontitis model]
[Impacts of atovastatin and tinidazole on cardiac muscle inflammation factors of tumor necrosis factor-?, interleukin-1 and metalloproteinase-2 of experimental rabbits with atherosclerosis and periodontitis].
[Protective effect of baicalin on experimental periodontitis in rats and its possible mechanisms]
Peripheral Arterial Disease
Inflammatory biomarkers, vascular procedures of lower limbs, and wound healing.
Is cardiovascular disease in patients with diabetes associated with serum levels of MMP-2, LOX, and the elastin degradation products ELM and ELM-2?
Plasma levels and zymographic activities of matrix metalloproteinases 2 and 9 in type II diabetics with peripheral arterial disease.
Protease-resistant stromal cell-derived factor-1 for the treatment of experimental peripheral artery disease.
Peripheral Nerve Injuries
Role of Matrix Metalloproteinases and Therapeutic Benefits of Their Inhibition in Spinal Cord Injury.
Peritoneal Fibrosis
A case of encapsulating peritoneal sclerosis at the clinical early stage with high concentration of matrix metalloproteinase-2 in peritoneal effluent.
Abatacept as a therapeutic option in the treatment of encapsulated peritoneal sclerosis: an experimental rat model.
CAN EFFLUENT MATRIX METALLOPROTEINASE 2 AND PLASMINOGEN ACTIVATOR INHIBITOR 1 BE USED AS BIOMARKERS OF PERITONEAL MEMBRANE ALTERATIONS IN PERITONEAL DIALYSIS PATIENTS?
Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis.
Inhibitory effects of matrix metalloproteinase inhibitor ONO-4817 on morphological alterations in chlorhexidine gluconate-induced peritoneal sclerosis rats.
Peritoneal Effluent MMP-2 and PAI-1 in Encapsulating Peritoneal Sclerosis.
Pioglitazone reduces peritoneal fibrosis via inhibition of TGF-?, MMP-2, and MMP-9 in a model of encapsulating peritoneal sclerosis.
The effects of interferon alpha2b on chemically-induced peritoneal fibrosis and on peritoneal tissue MMP-2 and TIMP-2 levels in rats.
The effects of low-dose erythropoiesis-stimulating agents on peritoneal fibrosis induced by chemical peritonitis and on peritoneal tissue MMP-2 and TIMP-2 Levels in rats.
The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in Japan.
What does the dialysate level of matrix metalloproteinase 2 tell us?
Peritoneal Neoplasms
DJ-1 is involved in the peritoneal metastasis of gastric cancer through activation of the Akt signaling pathway.
Peritonitis
Alterations in proteoglycan components and histopathology of the peritoneum in uraemic and peritoneal dialysis (PD) patients.
Gelatinase B/matrix metalloproteinase-9 contributes to cellular infiltration in a murine model of zymosan peritonitis.
Gelatinase B/MMP-9 as an inflammatory marker enzyme in mouse zymosan peritonitis: comparison of phase-specific and cell-specific production by mast cells, macrophages and neutrophils.
HIGHER DIALYSATE MATRIX METALLOPROTEINASE-2 LEVELS ARE ASSOCIATED WITH PERITONEAL MEMBRANE DYSFUNCTION.
IS256 abolishes gelatinase activity and biofilm formation in a mutant of the nosocomial pathogen Enterococcus faecalis V583.
Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B.
Peritonitis increases MMP-9 activity in peritoneal effluent from CAPD patients.
Prospective evaluation of virulence factors of enterococci isolated from patients with peritonitis: impact on outcome.
Resolvin D3 multi-level proresolving actions are host protective during infection.
Role of lymphocytes in the course of murine zymosan-induced peritonitis.
The effects of low-dose erythropoiesis-stimulating agents on peritoneal fibrosis induced by chemical peritonitis and on peritoneal tissue MMP-2 and TIMP-2 Levels in rats.
The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in Japan.
Pheochromocytoma
Prognostic markers in pheochromocytoma.
Phyllodes Tumor
Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin.
Pituitary ACTH Hypersecretion
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
Pituitary Neoplasms
CD147 expression in pituitary adenomas and its significance for clinical outcome.
Different patterns of gelatinolytic activity in pituitary macro- and microadenomas.
Effect of Hypoxia on DDR1 Expression in Pituitary Adenomas.
Enhancement of pituitary adenoma cell invasion and adhesion is mediated by discoidin domain receptor-1.
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
High levels of matrix metalloproteinases regulate proliferation and hormone secretion in pituitary cells.
Matrix metalloproteinase 2 and 9 expression correlated with cavernous sinus invasion of pituitary adenomas.
Matrix metalloproteinase-2 expression correlates with cavernous sinus invasion in pituitary adenomas.
Matrix metalloproteinase-9 and -2 and tissue inhibitor of matrix metalloproteinase-2 in invasive pituitary adenomas: A systematic review and meta-analysis of case-control trials.
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Pituitary Adenomas: Possible Markers of Neuroendocrine Cells.
Molecular Network Basis of Invasive Pituitary Adenoma: A Review.
Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).
Role of MMP-2 (-1306?C/T) Polymorphism in Pituitary Adenoma.
Type IV collagenase activity and cavernous sinus invasion in human pituitary adenomas.
Up-regulation of the expressions of MiR-149-5p and MiR-99a-3p in exosome inhibits the progress of pituitary adenomas.
[Expression of MMPPs and TIMP and invasiveness in pituitary adenomas]
[Role of matrix metalloproteinases-9, 2 and their inhibitor-TIMP-1, 2 in invasive pituitary adenomas biological behavior]
Placenta Accreta
Possible Role of TGF-?1, MMP-2, E-CAD, ?-Catenin and Antioxidants in Pathogenesis of Placenta Accreta.
What is the role of matrix metalloproteinase-2 in placenta percreta?
[Involvement of matrix metalloproteinase-2, -9, and tissue inhibitors of metalloproteinase-1, 2 in occurrence of the accrete placenta]
Placenta Previa
Placenta previa may acquire invasive nature by factors associated with epithelial-mesenchymal transition and matrix metalloproteinases.
Placenta, Retained
Activity of 72-kDa and 92-kDa matrix metalloproteinases in placental tissues of cows with and without retained fetal membranes.
Plasmacytoma
Bone marrow angiogenesis and plasma cell angiogenic and invasive potential in patients with active multiple myeloma.
Bone marrow angiogenesis in patients with active multiple myeloma.
Pleural Effusion
Gelatinolytic activities (matrix metalloproteinase-2 and -9) and soluble extracellular domain of Her-2/neu in pleural effusions.
Human pleural effusions are rich in matrix metalloproteinases.
Matrix metalloproteinase levels in the differentiation of parapneumonic pleural effusions.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 type IV collagenases in serum of patients with pleural effusions.
Matrix metalloproteinases 2 and 9 increase permeability of sheep pleura in vitro.
Occurrence of matrix metalloproteinases and tissue inhibitors of metalloproteinases in tuberculous pleuritis.
Pleural injury and pleurisy-induced progelatinase B/proMMP-9 is associated with markers of neutrophil degranulation.
[Matrix metalloproteinases and their inhibitors in lung cancer with malignant pleural effusion]
Pleurisy
Occurrence of matrix metalloproteinases and tissue inhibitors of metalloproteinases in tuberculous pleuritis.
Pleural injury and pleurisy-induced progelatinase B/proMMP-9 is associated with markers of neutrophil degranulation.
Potential role of matrix metalloproteinase-2,-9 and tissue inhibitors of metalloproteinase-1,-2 in exudative pleural effusions.
Pneumoconiosis
Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case-control study.
Pneumonia
Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro.
Early and late pulmonary effects of nebulized LPS in mice: An acute lung injury model.
Elevated serum matrix metalloproteinase-2 and -9 and their correlations with severity of disease in patients with community-acquired pneumonia.
Gelatinolytic and type IV collagenolytic activity in bronchiectasis.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-? in mice.
Impact of Time on Fluid Resuscitation with Hypertonic Saline (NaCl 7.5%) in Rats with LPS-Induced Acute Lung Injury.
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
MMP-9 as a marker of inflammation in tracheal epithelial lining fluid (TELF) and in bronchoalveolar fluid (BALF) of COPD horses.
Ophiopogon japonicus inhibits radiation-induced pulmonary inflammation in mice.
Overexpression of Tumor Necrosis Factor-? in the Lungs Alters Immune Response, Matrix Remodeling, and Repair and Maintenance Pathways.
Pathogenic role of matrix metalloproteases and their inhibitors in asthma and chronic obstructive pulmonary disease and therapeutic relevance of matrix metalloproteases inhibitors.
Transforming growth factor-?1 suppresses the up-regulation of matrix metalloproteinase-2 by lung fibroblasts in response to tumor necrosis factor-?.
[The pathogenicity enzymes of clinical strains of Klebsiella pneumoniae]
Pneumonia, Bacterial
[Study on inflammatory response and alteration of biochemical components in BALF from Pneumocystis carinii pneumonia]
Pneumoperitoneum
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Pneumothorax
Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax.
Correlation of matrix metalloproteinase-2 and -9 expression with recurrences in primary spontaneous pneumothorax patients.
Polycystic Kidney Diseases
Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Tubular gelatinase A (MMP-2) and its tissue inhibitors in polycystic kidney disease in the Han:SPRD rat.
Polycystic Kidney, Autosomal Dominant
Angiogenesis in autosomal-dominant polycystic kidney disease.
Dissection of Iliac Artery in a Patient With Autosomal Dominant Polycystic Kidney Disease: A Case Report.
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm.
Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease.
Polycystic Ovary Syndrome
Elevated serum levels of matrix metalloproteinase-2 in women with polycystic ovarian syndrome.
Increased circulating levels of matrix metalloproteinase-2 and -9 in women with the polycystic ovary syndrome.
Metformin treatment alleviates polycystic ovary syndrome by decreasing the expression of MMP-2 and MMP-9 via H19/miR-29b-3p and AKT/mTOR/autophagy signaling pathways.
Oral contraceptive containing chlormadinone acetate and ethinylestradiol reduces plasma concentrations of matrix metalloproteinase-2 in women with polycystic ovary syndrome.
Significance of matrix metalloproteinases in the pathophysiology of the ovary and uterus.
Polycythemia Vera
Importance of plasma matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinase (TIMP) in development of fibrosis in agnogenic myeloid metaplasia.
Polymyositis
Expression of matrix metalloproteinases in the muscle of patients with inflammatory myopathies.
Polyneuropathies
Expression pattern of matrix metalloproteinases-2 and -9 and their tissue inhibitors in patients with chronic inflammatory demyelinating polyneuropathy.
Matrix metalloproteinase-2 is involved in myelination of dorsal root ganglia neurons.
Matrix metalloproteinases-9 and -2 in secondary vasculitic neuropathies.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Expression pattern of matrix metalloproteinases-2 and -9 and their tissue inhibitors in patients with chronic inflammatory demyelinating polyneuropathy.
Matrix metalloproteinase upregulation in chronic inflammatory demyelinating polyneuropathy and nonsystemic vasculitic neuropathy.
Porphyria Cutanea Tarda
Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts.
Porphyrias
Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts.
Pouchitis
Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis.
Pre-Eclampsia
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Altered Maternal Serum Matrix Metalloproteinases MMP-2, MMP-3, MMP-9, and MMP-13 in Severe Early- and Late-Onset Preeclampsia.
AP-2? suppresses invasion in BeWo cells by repression of matrix metalloproteinase-2 and -9 and up-regulation of E-cadherin.
Association between matrix metalloproteinase (MMP)-2 polymorphisms and MMP-2 levels in hypertensive disorders of pregnancy.
CXCR2 is decreased in preeclamptic placentas and promotes human trophoblast invasion through the Akt signaling pathway.
Dysregulated expression of matrix metalloproteinases and their inhibitors may participate in the pathogenesis of pre-eclampsia and fetal growth restriction.
Effects of Matrix Metalloproteinase (MMP)-2 Polymorphisms on Responsiveness to Antihypertensive Therapy of Women with Hypertensive Disorders of Pregnancy.
Elevated expression of KiSS-1 in placenta of preeclampsia and its effect on trophoblast.
Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy.
Gelatinase matrix metalloproteinase (MMP)-2 and MMP-9 of the umbilical cord blood in preeclampsia.
Gene expression analysis of MMPs in women with preeclampsia using cell-free fetal RNA in maternal plasma.
Increased urinary levels of podocyte glycoproteins, matrix metallopeptidases, inflammatory cytokines, and kidney injury biomarkers in women with preeclampsia.
Matrix metalloproteinase enhances big-endothelin-1 constriction in mesenteric vessels of pregnant rats with reduced uterine blood flow.
Matrix metalloproteinase multiplex screening identifies increased MMP-2 urine concentrations in women predicted to develop preeclampsia.
Matrix metalloproteinase-2 C-735T and its interaction with matrix metalloproteinase-7 A-181G polymorphism are associated with the risk of preeclampsia: influence on total antioxidant capacity and blood pressure.
Matrix metalloproteinase-2 is elevated in midtrimester amniotic fluid prior to the development of preeclampsia.
Matrix metalloproteinase-2 is elevated in the plasma of women with preeclampsia.
Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia.
Matrix metalloproteinases MMP-2 and MMP-9 as markers for the prediction of preeclampsia in the first trimester.
Matrix Metalloproteinases MMP-2 and MMP-9 Occupy a New Role in Severe Preeclampsia.
Matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinases -9 (MMP-9) are differentially expressed in different regions of normal and preeclampsia placentae.
Midregional pro-adrenomedullin and matrix metalloproteinase-2 levels in intrauterine growth restriction and small gestational age pregnancies: biochemical diagnostic difference.
MMP-2 and MMP-9 Polymorphisms and Preeclampsia Risk in Tunisian Arabs: A Case-Control Study.
MMP-2 levels are elevated in the plasma of women who subsequently develop preeclampsia.
New Insights into the Role of Matrix Metalloproteinases in Preeclampsia.
Ratio of matrix metalloproteinase-2 to -9 is a more accurate predictive biomarker in women with suspected pre-eclampsia.
Relationship between 3D Power Doppler Ultrasound and Serum MMP-2 and Ang-2 Levels in Pregnant Women with Preeclampsia.
Role of Gelatinases MMP-2 and MMP-9 in Healthy and Complicated Pregnancy and Their Future Potential as Preeclampsia Biomarkers.
The activity of collagen-degrading enzymes of Wharton's jelly in EPH gestosis (pre-eclampsia).
The effect of serum from women with preeclampsia on JAR (trophoblast-like) cell line.
The effects of preeclampsia and oxygen environment on endothelial release of matrix metalloproteinase-2.
TNF-? inhibits trophoblast integration into endothelial cellular networks.
Up-regulation of miR-517-5p inhibits ERK/MMP-2 pathway: potential role in preeclampsia.
Vascular endothelial growth factor induces endothelin-1 production via matrix metalloproteinase-2 rather than endothelin-converting enzyme-1.
[Differences between the expression of matrix metalloproteinase-2, 9 in preeclampsia and normal placental tissues]
[Effect of microRNA-106b on the invasion and proliferation of trophoblasts through targeting MMP-2].
[Expression and significance of SATB1 and wnt/?-catenin signaling molecule in the placenta of preeclampsia].
[Expression of trophoblast invasion related genes mRNA and protein in human placenta in preeclampsia]
[Homocysteine decreases the invasion in cultured human trophoblasts: relationship between homocysteine and matrix metalloproteinase-2, -9 expression]
[Inhibitory effects of soluble endoglin on invasive ability of cultured cytotrophoblasts of first trimester of pregnancy.]
[The markers of inflammation reaction and dysfunction of endothelium in pregnant women with hypertension disorders of various genesis].
Precancerous Conditions
Expression of matrix metalloproteinase-1, -2 and -3 in squamous cell carcinoma and actinic keratosis.
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Spontaneous and cytokine-evoked production of matrix metalloproteinases by bone marrow and peripheral blood pre-B cells in childhood acute lymphoblastic leukaemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA methylation-mediated silencing of microRNA-204 enhances T cell acute lymphoblastic leukemia by up-regulating MMP-2 and MMP-9 via NF-?B.
Proteolytic activity of human lymphoid tumor cells. Correlation with tumor progression.
Secretion of MMP-2 and MMP-9 induced by VEGF autocrine loop correlates with clinical features in childhood acute lymphoblastic leukemia.
The Relationship Between MMP-2 -1306C>T and MMP-9 -1562C>T Polymorphisms and the Risk and Prognosis of T-Cell Acute Lymphoblastic Leukemia in a Chinese Population: A Case-Control Study.
[Expression and clinical significance of MMP-2 and MMP-9 in B acute lymphoblastic leukemia].
[Plasma matrix metalloproteinases MMP-2 and MMP-9 and tissue inhibitors TIMP-1 and TIMP-2 in children treated for acute lymphoblastic leukemia]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
DNA methylation-mediated silencing of microRNA-204 enhances T cell acute lymphoblastic leukemia by up-regulating MMP-2 and MMP-9 via NF-?B.
The Relationship Between MMP-2 -1306C>T and MMP-9 -1562C>T Polymorphisms and the Risk and Prognosis of T-Cell Acute Lymphoblastic Leukemia in a Chinese Population: A Case-Control Study.
Pregnancy Complications
Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes.
Pregnancy, Ectopic
Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.
Immunohistochemical expression of matrix metalloproteinases 1 and 2 (MMP-1 and MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in ruptured and non-ruptured tubal ectopic pregnancies.
Pregnancy, High-Risk
Activities of matrix metalloproteinase-2 and -9 in amniotic fluid at parturition in mares with normal and high-risk pregnancy.
Pregnancy, Tubal
Co-ordinated expression of MMP-2 and its putative activator, MT1-MMP, in human placentation.
Dynamic expression of matrix metalloproteinases (MMP-2, -9 and -14) and the tissue inhibitors of MMPs (TIMP-1, -2 and -3) at the implantation site during tubal pregnancy.
Immunohistochemical expression of matrix metalloproteinases 1 and 2 (MMP-1 and MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in ruptured and non-ruptured tubal ectopic pregnancies.
Premature Birth
Genetic variation associated with preterm birth in African-American women.
Maternal infection with Schistosoma japonicum induces a profibrotic response in neonates.
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Pressure Ulcer
Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids.
[Expression and significance of tumor necrosis factor alpha, matrix metalloproteinase 2 and collagen in skin tissue of pressure ulcer of rats].
Primary Myelofibrosis
Elevated plasma levels of TIMP-1 correlate with plasma suPAR/uPA in patients with chronic myeloproliferative disorders.
Primary Ovarian Insufficiency
Association study of five functional polymorphisms in matrix metalloproteinase-2, -3, and -9 genes with risk of primary ovarian insufficiency in Korean women.
Prolactinoma
Expression of serine proteases and metalloproteinases in human pituitary adenomas and anterior pituitary lobe tissue.
Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-2: Prognostic biological markers in invasive prolactinomas.
Prostatic Diseases
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Prostatic Hyperplasia
Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Association between MMP-2 expression and prostate cancer: A meta-analysis.
CD147, MMP-1, MMP-2 and MMP-9 Protein Expression as Significant Prognostic Factors in Human Prostate Cancer.
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Immunohistochemical analysis of type IV collagenase expression in prostatic hyperplasia and adenocarcinoma.
Immunohistochemical studies of the expression of matrix metalloproteinase-2 and metalloproteinase-9 in human prostate cancer.
In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer.
Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells.
MMP-2 detective silicon nanowire biosensor using enzymatic cleavage reaction.
Plasminogen activator activities in short-term tissue cultures of benign prostatic hyperplasia and prostatic carcinoma.
Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue.
Prostatic Intraepithelial Neoplasia
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse.
Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia.
Increased expression of the 72-kd type IV collagenase in prostatic adenocarcinoma. Demonstration by immunohistochemistry and in situ hybridization.
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Prostatic Neoplasms
(±)Equol inhibits invasion in prostate cancer DU145 cells possibly via down-regulation of matrix metalloproteinase-9, matrix metalloproteinase-2 and urokinase-type plasminogen activator by antioxidant activity.
A short-hairpin RNA targeting osteopontin downregulates MMP-2 and MMP-9 expressions in prostate cancer PC-3 cells.
Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Activator protein 2alpha transcription factor expression is associated with luminal differentiation and is lost in prostate cancer.
Activities and polymorphisms of MMP-2 and MMP-9, smoking, diabetes and risk of prostate cancer.
ADAM17 targets MMP-2 and MMP-9 via EGFR-MEK-ERK pathway activation to promote prostate cancer cell invasion.
Adenovirus-mediated expression of TIMP-1 and TIMP-2 in bone inhibits osteolytic degradation by human prostate cancer.
Adipocyte-derived monocyte chemotactic protein-1 (MCP-1) promotes prostate cancer progression through the induction of MMP-2 activity.
Amplification of MMP-2 and MMP-9 production by prostate cancer cell lines via activation of protease-activated receptors.
Androgen receptor and invasion in prostate cancer.
Androgen stimulates matrix metalloproteinase-2 expression in human prostate cancer.
Assessment of indirect hemagglutination and zymography procedures in evaluation of gelatinase a in patients with benign and malignant prostate hyperplasia.
Association between MMP-2 expression and prostate cancer: A meta-analysis.
Association of Promoter Polymorphisms in MMP 2 and TIMP2 with Prostate Cancer Susceptibility in North India.
Autocrine factors, type IV collagenase secretion and prostatic cancer cell invasion.
Bee Venom Components as Therapeutic Tools against Prostate Cancer.
Blockade of the type I IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3, and suppresses MMP-2 expression.
Bruton's Tyrosine Kinase (BTK) Inhibitor (Ibrutinib)?-Suppressed Migration and Invasion of Prostate Cancer.
CD147, MMP-1, MMP-2 and MMP-9 Protein Expression as Significant Prognostic Factors in Human Prostate Cancer.
Characterization of protease expression in human prostate-cancer cell-lines.
Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer.
Circulating levels of VCAM and MMP-2 may help identify patients with more aggressive prostate cancer.
Comparative study of stromal metalloproteases expression in patients with benign hyperplasia and prostate cancer.
Concise syntheses of the abyssinones and discovery of new inhibitors of prostate cancer and MMP-2 expression.
Concomitant reduction of matrix metalloproteinase-2 secretion and intracellular reactive oxygen species following anti-sense inhibition of telomerase activity in PC-3 prostate carcinoma cells.
Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique.
Determination of gelatinase A using a modified indirect hemagglutination assay in human prostate cancer screening and assessment of its correlation with prostate-specific antigen parameters.
Different mRNA and protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 in benign and malignant prostate tissue.
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Differential expression of matrix metalloproteinase-2 expression in disseminated tumor cells and micrometastasis in bone marrow of patients with nonmetastatic and metastatic prostate cancer: theoretical considerations and clinical implications-an immunocytochemical study.
Dual androgen-response elements mediate androgen regulation of MMP-2 expression in prostate cancer cells.
E2F5 promotes prostate cancer cell migration and invasion through regulation of TFPI2, MMP-2 and MMP-9.
Effect of 17beta-estradiol on apoptosis, IGF system components and gelatinases A and B in prostate cancer cells (PC-3).
Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.
Enhancing Accumulation and Penetration of HPMA Copolymer-Doxorubicin Conjugates in 2D and 3D Prostate Cancer Cells via iRGD Conjugation with an MMP-2 Cleavable Spacer.
Estrogens promote invasion of prostate cancer cells in a paracrine manner through up-regulation of matrix metalloproteinase 2 in prostatic stromal cells.
Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression.
Expression of matrix metalloproteinase-2 and prostate-specific antigen in localized and metastatic prostate cancer.
Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells.
Expression of matrix metalloproteinases (MMP-2 and -9) and their inhibitors (TIMP-1 and -2) in prostate cancer tissue.
Filamin C, a dysregulated protein in cancer revealed by label-free quantitative proteomic analyses of human gastric cancer cells.
Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways.
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.
Genistein treatment duration effects biomarkers of cell motility in human prostate.
Genistein-selenium combination induces growth arrest in prostate cancer cells.
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity.
High matrix metalloproteinase-to-E-cadherin ratio measured by bicolor fluorescent in situ hybridization is associated with lymphangiogenesis and lymph node metastasis in prostate cancer.
High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells.
Human chorionic gonadotropin ? induces migration and invasion via activating ERK1/2 and MMP-2 in human prostate cancer DU145 cells.
IL-10 blocks collagen IV invasion by "invasion stimulating factor" activated PC-3 ML cells: upregulation of TIMP-1 expression.
Immunohistochemical studies of activated matrix metalloproteinase-2 (MMP-2a)expression in human prostate cancer.
Immunohistochemical studies of the expression of matrix metalloproteinase-2 and metalloproteinase-9 in human prostate cancer.
In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer.
Influence of genistein isoflavone on matrix metalloproteinase-2 expression in prostate cancer cells.
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor.
Inhibition of tumorigenic potential and prostate-specific antigen expression in LNCaP human prostate cancer cell line by 13-cis-retinoic acid.
Integrin ?v?6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2.
Kindlin-2 promotes invasiveness of prostate cancer cells via NF-?B-dependent upregulation of matrix metalloproteinases.
Limited processing of pro-matrix metalloprotease-2 (gelatinase A) overexpressed by transfection in PC-3 human prostate tumor cells: association with restricted cell surface localization of membrane-type matrix metalloproteinase-1.
LOX-1 activation by oxLDL triggers an epithelial mesenchymal transition and promotes tumorigenic potential in prostate cancer cells.
LOX-1 receptor: A potential link in atherosclerosis and cancer.
Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis.
MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer.
Matrix metalloproteinase and heparin-stimulated serine proteinase activities in post-prostate massage urine of men with prostate cancer.
Matrix metalloproteinase-2 and -9 in the urine of prostate cancer patients.
Matrix metalloproteinase-2 contributes to increased platelet reactivity in patients with metastatic prostate cancer: a preliminary study.
Matrix metalloproteinase-2 in blood does not indicate the progression of prostate cancer.
Matrix metalloproteinase-2 polymorphism is associated with prognosis in prostate cancer.
Matrix metalloproteinases 2 and 9 immunoexpression in prostate carcinoma at the positive margin of radical prostatectomy specimens.
MEK4 function, genistein treatment, and invasion of human prostate cancer cells.
Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.
Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry.
miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression.
MMP-2 detective silicon nanowire biosensor using enzymatic cleavage reaction.
MMP-2, MMP-9 and activin A blood levels in patients with breast cancer or prostate cancer metastatic to the bone.
Molecular mechanisms of the antimetastatic activity of nuclear clusterin in prostate cancer cells.
Neuropeptides induce Mr 92,000 type IV collagenase (matrix metalloprotease-9) activity in human prostate cancer cell lines.
Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-beta1 in human prostate cancer cell lines.
Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells.
ODAM is a predictor for biomedical recurrence and inhibits the migration and invasion of prostate cancer.
Over-expression of hypoxia-inducible factor-1alpha increases the invasive potency of LNCaP cells in vitro.
Overexpression of short TRPM8 variant ? promotes cell migration and invasion, and decreases starvation-induced apoptosis in prostate cancer LNCaP cells.
P504S expressing circulating prostate cells as a marker for prostate cancer.
PD98059-inhibited invasion of Dunning rat prostate cancer cells involves suppression of motility but not MMP-2 or uPA secretion.
Pinin promotes tumor progression via activating CREB through PI3K/AKT and ERK/MAPK pathway in prostate cancer.
Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production.
Polymorphisms in MMP-2 and TIMP-2 in Turkish patients with prostate cancer.
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways.
Prognostic significance of matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expression in prostate cancer.
Protein kinase D1 inhibits cell proliferation through matrix metalloproteinase-2 and matrix metalloproteinase-9 secretion in prostate cancer.
Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers.
Rho-Associated Protein Kinase (ROCK) Promotes Proliferation and Migration of PC-3 and DU145 Prostate Cancer Cells by Targeting LIM Kinase 1 (LIMK1) and Matrix Metalloproteinase-2 (MMP-2).
RNA-based markers in biopsy cores with atypical small acinar proliferation: Predictive effect of T2E fusion positivity and MMP-2 upregulation for a subsequent prostate cancer diagnosis.
Role of RUNX3 in suppressing metastasis and angiogenesis of human prostate cancer.
Roles of matrix metalloproteinases and their natural inhibitors in prostate cancer progression.
Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.
Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension.
Significance of MMP-2 expression in prostate cancer: an immunohistochemical study.
Silencing of a novel tumor metastasis suppressor gene LASS2/TMSG1 promotes invasion of prostate cancer cell in vitro through increase of vacuolar ATPase activity.
Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell.
Silibinin inhibits prostate cancer invasion, motility and migration by suppressing vimentin and MMP-2 expression.
SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells.
SKI-606 (Bosutinib) Blocks Prostate Cancer Invasion, Growth, and Metastasis In vitro and In vivo through Regulation of Genes Involved in Cancer Growth and Skeletal Metastasis.
SPAG9 expression is increased in human prostate cancer and promotes cell motility, invasion and angiogenesis in vitro.
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
The p75(NTR) metastasis suppressor inhibits urokinase plasminogen activator, matrix metalloproteinase-2 and matrix metalloproteinase-9 in PC-3 prostate cancer cells.
The role of the androgen receptor in prostate cancer-induced platelet aggregation and platelet-induced invasion.
Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression.
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells - A critical role of Cdk1 in mitotic entry.
Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue.
Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.
Underexpression of MMP-2 and its regulators, TIMP2, MT1-MMP and IL-8, is associated with prostate cancer.
Vasoactive intestinal peptide behaves as a pro-metastatic factor in human prostate cancer cells.
[Effects of FRZB on growth and metastasis of gastric cancer cell line SGC-7901]
[Inhibitory effect of 3-bromopyruvate on the proliferation, migration and invasive ability of prostate cancer PC-3 cells].
[Over-expression of Hypoxia-inducible factor 1alpha increases invasive potency of LNCaP cells in vitro]
[P2Y purinergic receptor activated PI-3K/Akt signaling pathway in regulation of growth and invasion of prostatic cancer]
[Prognostic value of stromal immunolabelling by MMP-2, MT1-MMP and TIMP-2 in clinically localized prostate cancer]
Prostatitis
Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.
Matrix metalloproteinases in the pathogenesis of estradiol-induced nonbacterial prostatitis in the lateral prostate lobe of the Wistar rat.
protein-glutamine gamma-glutamyltransferase deficiency
Association between expression of MMP-2 and MMP-9 genes and pathogenesis of intracranial hemorrhage in severe coagulation factor XIII deficiency.
Expression and CpG island methylation pattern of MMP-2 and MMP-9 genes in patients with congenital factor XIII deficiency and intracranial hemorrhage.
Proteinuria
Chronic humoral rejection of human kidney allografts is associated with MMP-2 accumulation in podocytes and its release in the urine.
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Circulating matrix metalloproteinase-2 is associated with cystatin C level, posttransplant duration, and diabetes mellitus in kidney transplant recipients.
Delivery of megsin siRNA plasmid reveals therapeutic potential against diabetic nephropathy by down-regulating p27kip1 level.
Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis.
Increased plasma matrix metalloproteinase-2 (MMP-2), tissue inhibitor of proteinase-1 (TIMP-1), TIMP-2, and urine MMP-2 concentrations correlate with proteinuria in renal transplant recipients.
Integrin alpha1beta1 regulates matrix metalloproteinases via P38 mitogen-activated protein kinase in mesangial cells: implications for Alport syndrome.
Loss of diacylglycerol kinase ? causes thrombotic microangiopathy by impairing endothelial VEGFA signaling.
Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice.
Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease.
The role of matrix metalloproteinases 2 in atherosclerosis of patients with chronic kidney disease in type 2 diabetes.
Treatment of experimental immune complex glomerulonephritis by sodium alginate.
Urinary Metalloproteinases-9 and -2 and Their Inhibitors TIMP-1 and TIMP-2 are Markers of Early and Long-Term Graft Function After Renal Transplantation.
[Urinalysis in patients at the early stage of acute pancreatitis].
Pruritus
Effects of combined Pulsed Dye Laser and Fractional CO2 Laser treatment of burn scars and correlation with plasma levels of collagen type I, MMP-2 and TIMP-1.
Pseudoxanthoma Elasticum
Dermal fibroblasts from pseudoxanthoma elasticum patients have raised MMP-2 degradative potential.
Elevated circulating levels of matrix metalloproteinases MMP-2 and MMP-9 in pseudoxanthoma elasticum patients.
Psoriasis
Basement membrane alterations in psoriasis are accompanied by epidermal overexpression of MMP-2 and its inhibitor TIMP-2.
Decreased levels of metalloproteinase-9 and angiogenic factors in skin lesions of patients with psoriatic arthritis after therapy with anti-TNF-alpha.
Effective Therapy with Anti-TNF-{alpha} in Patients with Psoriatic Arthritis Is Associated with Decreased Levels of Metalloproteinases and Angiogenic Cytokines in the Sera and Skin Lesions.
Genotype association of C(-735)T polymorphism in matrix metalloproteinase 2 gene with G(8002)A endothelin 1 gene with plaque psoriasis.
Local antimicrobial, protease and cytokine defense systems in psoriatic skin.
Matrix metalloproteinase-2 promoter variability in psoriasis.
The Increased Expression of Matrix Metalloproteinase-9 Messenger RNA in the Non-lesional Skin of Patients with Large Plaque Psoriasis Vulgaris.
Therapy of psoriasis with narrowband ultraviolet-B light influences plasma concentrations of MMP-2 and TIMP-2 in patients.
VEGF is likely a key factor in the link between inflammation and angiogenesis in psoriasis: results of an immunohistochemical study.
Pterygium
Expression of gelatinase (MMP-2 and MMP-9) in pterygia and pterygium fibroblasts is increased with disease progression and activation of protein kinase C.
Pterygia pathogenesis: corneal invasion by matrix metalloproteinase expressing altered limbal epithelial basal cells.
The Nuclear-Factor Kappa B Pathway is Activated in Pterygium.
[Expression of matrix metalloproteinase in human pterygia]
Puerperal Infection
Protease production by microorganisms associated with reproductive tract infection.
Pulmonary Alveolar Proteinosis
Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor.
Pulmonary Arterial Hypertension
Involvement of matrix metalloproteinase-2 in medial hypertrophy of pulmonary arterioles in broiler chickens with pulmonary arterial hypertension.
Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension.
MMP-2 and MMP-9 contribute to the angiogenic effect produced by hypoxia/15-HETE in pulmonary endothelial cells.
Pulmonary Atelectasis
Inhibition of matrix metalloproteinases in gerbil cholesteatoma: preliminary findings.
Pulmonary Disease, Chronic Obstructive
Activity of matrix metalloproteinase in airway epithelial cells of COPD patients.
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-?B pathway.
An Insight into COPD Morphopathogenesis: Chronic Inflammation, Remodeling, and Antimicrobial Defense.
Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population.
Cigarette smoke exposure inhibits extracellular MMP-2 (gelatinase A) activity in human lung fibroblasts.
Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts.
Delay of airway epithelial wound repair in COPD is associated with airflow obstruction severity.
Elevated serum matrix metalloprotease (MMP-2) as a candidate biomarker for stable COPD.
Enhanced levels of prostaglandin E2 and matrix metalloproteinase-2 correlate with the severity of airflow limitation in stable COPD.
Expression of Matrix Metalloproteinase-2, Matrix Metalloproteinase-9, Tissue Inhibitor of Metalloproteinase-1, and Changes in Alveolar Septa in Patients with Chronic Obstructive Pulmonary Disease.
Genetic polymorphisms of matrix metalloproteinases and protein levels in chronic obstructive pulmonary disease in a Mexican population.
Glucocorticosteroids Differentially Regulate MMP-9 and Neutrophil Elastase in COPD.
Identification of patients with chronic obstructive pulmonary disease (COPD) by measurement of plasma biomarkers.
Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space.
Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD.
Induced sputum metalloproteinases and their inhibitors in relation to exhaled nitrogen oxide and sputum nitric oxides and other inflammatory cytokines in patients with chronic obstructive pulmonary disease.
Levels of angiopoietins 1 and 2 in induced sputum supernatant in patients with COPD.
Matrix metalloproteinase-2 protein in lung periphery is related to COPD progression.
Matrix metalloproteinase-9 in lung remodeling.
Matrix metalloproteinases in the pathogenesis of asthma and COPD: implications for therapy.
MMP-2 (-1306 C/T) Polymorphism Affects Serum Matrix Metalloproteinase (MMP)-2 Levels and Correlates with Chronic Obstructive Pulmonary Disease Severity: A Case-Control Study of MMP-1 and -2 in a Tunisian Population.
MMP-2- and MMP-9-linked gelatinolytic activity in the sputum from patients with asthma and chronic obstructive pulmonary disease.
MMP-9 as a marker of inflammation in tracheal epithelial lining fluid (TELF) and in bronchoalveolar fluid (BALF) of COPD horses.
MMP-9 protein level does not reflect overall MMP activity in the airways of patients with COPD.
Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease.
Prothymosin ? overexpression contributes to the development of pulmonary emphysema.
Simultaneous up-regulation of matrix metalloproteinases 1, 2, 3, 7, 8, 9 and tissue inhibitors of metalloproteinases 1, 4 in serum of patients with chronic obstructive pulmonary disease.
The BRD4 inhibitor JQ1 protects against chronic obstructive pulmonary disease in mice by suppressing NF-?B activation.
The cyclooxygenase-2-prostaglandin e2 pathway maintains senescence of chronic obstructive pulmonary disease fibroblasts.
TLR9 expression is required for the development of cigarette smoke-induced emphysema in mice.
[Expressions of cyclooxygenase-2 and matrix metalloproteinase-2 and airflow obstruction in patients with chronic obstructive pulmonary disease]
[Study on effect of anemoside B4 in improving COPD rats by regulating IL-12/STAT4 and IL-4/STAT6 signaling pathways].
[The role of matrix metalloproteinases in extracellular matrix remodelling in chronic obstructive pulmonary disease rat models]
Pulmonary Edema
Hyperoxia induces interstitial (type I) and increases type IV collagenase mRNA expression and increases type I and IV collagenolytic activity in newborn rat lung.
Pulmonary Emphysema
Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema.
Pulmonary Eosinophilia
Clinical findings, bronchoalveolar lavage fluid cytology and matrix metalloproteinase-2 and -9 in canine pulmonary eosinophilia.
Pulmonary Fibrosis
Activity of matrix metalloproteinase in airway epithelial cells of COPD patients.
Artesunate modulates expression of matrix metalloproteinases and their inhibitors as well as collagen-IV to attenuate pulmonary fibrosis in rats.
C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases.
Early and late changes of MMP-2 and MMP-9 in bleomycin-induced pulmonary fibrosis.
Effect of antisense TIMP-1 cDNA on the expression of TIMP-1 and MMP-2 in lung tissue with pulmonary fibrosis induced by bleomycin.
Effects of Chinese herbal medicine Shenlong Decoction on mRNA expressions of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in lung tissue of rats with pulmonary fibrosis induced by bleomycin.
Epimorphin expression in interstitial pneumonia.
Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin.
Inhibitory effects of total ginsenoside on bleomycin-induced pulmonary fibrosis in mice.
Matrix proteases, green tea, and St. John's wort: biomedical research catches up with folk medicine.
Relaxin attenuates silica-induced pulmonary fibrosis by regulating collagen type I and MMP-2.
Role of MMP-2 in alveolar epithelial cell repair after bleomycin administration in rabbits.
The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice.
The role of collagenases in experimental pulmonary fibrosis.
Time course of matrix metalloproteases and tissue inhibitors in bleomycin-induced pulmonary fibrosis.
Unbalanced MMP/TIMP-1 expression during the development of experimental pulmonary fibrosis with acute paraquat poisoning.
[Anti-type IV collagenase single-chain antibody ameliorates bleomycin-induced experimental pulmonary fibrosis in mice]
[Changes of matrix metalloproteinases activities in pulmonary fibrosis rats]
[Effects of Fuzheng Huayu recipe on MMP-2 activity and type IV collagen expression at fibrotic lung]
[Expression of matrix metalloproteinase-2 in rat pulmonary fibrosis]
[Inhibition of pulmonary fibrosis by doxycycline: an experiment with mice]
[mRNA expression of matrix metalloproteinase-2 and membrane type matrix metalloproteinase in pulmonary fibroblasts and macrophages of rat pulmonary fibrosis model]
[Perindopril and losartan attenuate bleomycin A5-induced pulmonary fibrosis in rats]
Pulpitis
Tissue levels of matrix metalloproteinases in pulps and periapical lesions.
Pycnodysostosis
Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate.
Pyelonephritis
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Mitochondria-Associated Matrix Metalloproteinases 2 and 9 in Acute Renal Pathologies.
Predictive Accuracy of Urinary neutrophil gelatinase associated lipocalin (NGAL) for renal parenchymal involvement in Children with Acute Pyelonephritis.
Urinary Measurement of Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Helps Diagnose Acute Pyelonephritis in a Preclinical Model.
Validity of Neutrophil Gelatinase Associated Lipocaline as a Biomarker for Diagnosis of Children with Acute Pyelonephritis.
Pyometra
Matrix metalloproteinases (MMPs) in the endometrium of bitches.
Radicular Cyst
Correlation between radiographic area and immunolocation of MMP-2 and MMP-9 in unilocular radiographic lesions.
Gene-expression analysis of matrix metalloproteinases 1 and 2 and their tissue inhibitors in chronic periapical inflammatory lesions.
Laminin-5 gamma 2 chain is colocalized with gelatinase-A (MMP-2) and collagenase-3 (MMP-13) in odontogenic keratocysts.
Metalloproteinases 2 and 9 Immunoexpression in Periapical Lesions from Primary Endodontic Infection: Possible Relationship with the Histopathological Diagnosis and the Presence of Pain.
Presence of myofibroblasts and matrix metalloproteinase 2 in radicular cysts, dentigerous cysts, and keratocystic odontogenic tumors: a comparative immunohistochemical study.
Rectal Neoplasms
Activity and expression of urokinase-type plasminogen activator and matrix metalloproteinases in human colorectal cancer.
Gelatinase B expression as a prognostic factor in patients with stage II/III rectal carcinoma treated by postoperative adjuvant therapy.
High formation of superoxide anion and nitric oxide, and matrix metalloproteinases activity in vascular wall of rectal carcinoma vessels.
Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer.
Pretreatment Expression of 13 Molecular Markers as a Predictor of Tumor Responses After Neoadjuvant Chemoradiation in Rectal Cancer.
Prognostic significance of matrix metalloproteinases-1, -2, -7 and -13 and tissue inhibitors of metalloproteinases-1, -2, -3 and -4 in colorectal cancer.
The matrix metalloproteinase-7 and pro-enzyme of metalloproteinase-1 as a potential marker for patients with rectal cancer without distant metastasis.
[Matrix metalloproteinase-2 expression and its correlation with mesorectal metastasis in middle and lower rectal cancer]
Refractive Errors
Assessment of the association of matrix metalloproteinases with myopia, refractive error and ocular biometric measures in an Australian cohort.
Effect of Bilberry Extract on Development of Form-Deprivation Myopia in the Guinea Pig.
Renal Insufficiency
Adenylyl cyclase-associated protein-1/CAP1 as a biological target substrate of gelatinase B/MMP-9.
Increased expression of HIF-1alpha, VEGF-A and its receptors, MMP-2, TIMP-1, and ADAMTS-1 at the venous stenosis of arteriovenous fistula in a mouse model with renal insufficiency.
Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury.
MMP-2 and TIMP-2 in Patients with Heart Failure and Chronic Kidney Disease.
Systematic separation and purification of elastase, gelatinase (matrix metalloproteinase 9), and collagenase (matrix metalloproteinase 8) from polymorphonuclear leukocytes in dialyzers previously used by patients with renal failure.
Renal Insufficiency, Chronic
Chronic humoral rejection of human kidney allografts is associated with MMP-2 accumulation in podocytes and its release in the urine.
Circulating Matrix Metalloproteinase-2 Is an Independent Correlate of Proteinuria in Patients with Chronic Kidney Disease.
Circulating matrix metalloproteinase-2 is associated with cystatin C level, posttransplant duration, and diabetes mellitus in kidney transplant recipients.
Determinants of circulating matrix metalloproteinase-2 and pregnancy-associated plasma protein-A in patients with chronic kidney disease.
Early Postoperative Neutrophil Gelatinase Associated Lipocalin Predicts the Development of Chronic Kidney Disease Following Liver Transplantation.
Expression of matrix metalloproteinases MMP-2 and MMP-9 is altered during nephrogenesis in fetuses from diabetic rats.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Matrix metalloproteinase -2, -9 and arterial stiffness in children and adolescents: The role of chronic kidney disease, diabetes, and hypertension.
Matrix Metalloproteinase 2 and Osteoprotegrin as New Markers of Increased Atherosclerotic Risk in Egyptian Patients with Chronic Kidney Disease.
Matrix metalloproteinase-2 and -9 exacerbate arterial stiffening and angiogenesis in diabetes and chronic kidney disease.
Matrix metalloproteinases and their role in the renal epithelial mesenchymal transition.
MMP-2 and 9 in Chronic Kidney Disease.
MMP-2 and TIMP-2 in Patients with Heart Failure and Chronic Kidney Disease.
Novel indicators of fibrosis-related complications in children with chronic kidney disease.
Peripheral blood level alterations of MMP-2 and MMP-9 in patients with chronic kidney disease on conservative treatment and on hemodialysis.
Relationships between circulating matrix metalloproteinase-2 and -9 and renal function in patients with chronic kidney disease.
Serum metalloproteinases MMP-2, MMP-9 and metalloproteinase tissue inhibitors TIMP-1 and TIMP-2 in patients on hemodialysis.
The expression of two isoforms of matrix metalloproteinase-2 in aged mouse models of diabetes mellitus and chronic kidney disease.
Upregulation of matrix metalloproteinase-2 in the arterial vasculature contributes to stiffening and vasomotor dysfunction in patients with chronic kidney disease.
Reperfusion Injury
Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity.
Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB.
Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: a new intracellular target for matrix metalloproteinase-2.
Distribution and activation of matrix metalloproteinase-2 in skeletal muscle fibers.
Doxycycline Reduces Cardiac Matrix Metalloproteinase-2 Activity but Does not Ameliorate Myocardial Dysfunction During Reperfusion in Coronary Artery Bypass Patients Undergoing Cardiopulmonary Bypass.
Imbalance between tissue inhibitor of metalloproteinase-4 and matrix metalloproteinases during acute myocardial [correction of myoctardial] ischemia-reperfusion injury.
Increased matrix metalloproteinase 9 activity and mRNA expression in lung ischemia-reperfusion injury.
Inhibition of MMP-2 expression with siRNA increases baseline cardiomyocyte contractility and protects against simulated ischemic reperfusion injury.
Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury.
Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance.
Ischemia-reperfusion injury stimulates gelatinase expression and activity in kidney glomeruli.
Junctophilin-2 is a target of matrix metalloproteinase-2 in myocardial ischemia-reperfusion injury.
Matrix metalloproteinase inhibitor (ONO-4817) attenuates ischemia-reperfusion injury in rat lung.
Matrix Metalloproteinase-2 (MMP-2) Gene Deletion Enhances MMP-9 Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice.
Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix.
Matrix metalloproteinase-2 contributes to ischemia-reperfusion injury in the heart.
Matrix metalloproteinase-2: an emerging biomarker for reperfusion injury following percutaneous coronary intervention.
Myocardial MMP-2 contributes to SERCA2a proteolysis during cardiac ischemia-reperfusion injury.
N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure.
Novel intracellular N-terminal truncated matrix metalloproteinase-2 isoform in skeletal muscle ischemia-reperfusion injury.
Serum matrix metalloproteinase MMP-2 and MMP-9 in the late phase of ischemia and reperfusion injury in human orthotopic liver transplantation.
Structure and proteolytic susceptibility of the inhibitory C-terminal tail of cardiac troponin I.
Targeting MMP-2 to treat ischemic heart injury.
Up-regulation of MMP-2 and MMP-9 leads to degradation of type IV collagen during skeletal muscle reperfusion injury; protection by the MMP inhibitor, doxycycline.
Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia.
Respiratory Distress Syndrome
Higher concentrations of matrix metalloproteinases in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome.
Matrix metalloproteinases and TIMP in acute respiratory distress syndrome.
Role of gelatinases MMP-2 and MMP-9 in tissue remodeling following acute lung injury.
Respiratory Hypersensitivity
Protective effects of tiotropium alone or combined with budesonide against cadmium inhalation induced acute neutrophilic pulmonary inflammation in rats.
Respiratory Insufficiency
Implications for matrix metalloproteinases as modulators of pediatric lung disease.
Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice.
Respiratory Tract Diseases
Gelatinolytic matrix metalloproteinases-2 and -9 in tracheobronchial lavage fluid obtained from calves with concurrent infections of Pasteurella multocida and Mycoplasma bovirhinis.
Retinal Degeneration
Matrix Metalloproteinases MMP-2 and MMP-9, Their Inhibitors TIMP-1 and TIMP-2, Vascular Endothelial Growth Factor and sVEGFR-2 as Predictive Markers of Ischemic Retinopathy in Patients with Systemic Sclerosis-Case Series Report.
Retinal Detachment
A feasible tool to detect mRNA expression of matrix metalloproteinases and their tissue inhibitors in human Tenon's capsule.
Potential Role of Zinc Dyshomeostasis in Matrix Metalloproteinase-2 and -9 Activation and Photoreceptor Cell Death in Experimental Retinal Detachment.
Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.
Statins in rhegmatogenous retinal detachment are associated with low intravitreal angiopoietin-2, VEGF and MMP-2 levels, and improved visual acuity gain in vitrectomized patients.
Retinal Dystrophies
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1 in the retinal pigment epithelium and interphotoreceptor matrix: vectorial secretion and regulation.
Retinal Neoplasms
Gelatinase expression in Retinoblastoma: Modulation of LHBETATAG retinal tumor development by Anecortave Acetate.
Retinal Neovascularization
Angiopoietin/Tek interactions regulate mmp-9 expression and retinal neovascularization.
ASSESSMENT OF GELATINASE AND TUMOR NECROSIS FACTOR-? LEVEL IN THE VITREOUS AND SERUM OF PATIENTS WITH EALES DISEASE: Role of Inflammation-Mediated Angiogenesis in the Pathogenesis of Eales Disease.
Inhibitory effects of arresten on bFGF-induced proliferation, migration, and matrix metalloproteinase-2 activation in mouse retinal endothelial cells.
Interaction between iNOS and COX-2 in hypoxia-induced retinal neovascularization in mice.
Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.
Reduced retinal angiogenesis in MMP-2-deficient mice.
Retinal vascular development and pathologic retinal angiogenesis are not impaired in matrix metalloproteinase-2 deficient mice.
VEGF Secreted by Hypoxic Muller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy.
Retinal Perforations
Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGF?1 in diabetic eyes undergoing vitrectomy.
Interleukin-1-beta changes the expression of metalloproteinases in the vitreous humor and induces membrane formation in eyes containing preexisting retinal holes.
Vitreous TIMP-1 levels associate with neovascularization and TGF-?2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy.
Retinal Vein Occlusion
Association of MMP2-1306C/T and TIMP2G-418C polymorphisms in retinal vein occlusion.
Association of MMP2-1306C/T Polymorphism with Ischemic Retinal Vein Occlusion.
Retinoblastoma
Antineoplastic activity of a nutrient mixture in Y-79 malignant retinoblastoma cells.
Characterization and novel activation of 72-kDa metalloproteinase in retinal interphotoreceptor matrix and Y-79 cell culture medium.
Clinicohistopathological implications of MMP/VEGF expression in retinoblastoma: a combined meta-analysis and bioinformatics analysis.
Curcumin suppressed proliferation and migration of human retinoblastoma cells through modulating NF-?B pathway.
Differential roles of matrix metalloproteinase-9 and -2, depending on proliferation or differentiation of retinoblastoma cells.
Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation.
Expression of MMP-2 and MMP-9 in retinoblastoma and their significance.
FoxM1 affects adhesive, migratory, and invasive abilities of human retinoblastoma Y-79 cells by targeting matrix metalloproteinase 2.
Gelatinase expression in Retinoblastoma: Modulation of LHBETATAG retinal tumor development by Anecortave Acetate.
HOW EXPRESSIONS OF CLAUDIN-1 AND MMP-2 IN RETINOBLASTOMA CORRELATE WITH HISTOLOGICAL DIFFERENTIATION AND OPTIC NERVE INVASION.
Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma.
Insights on ornithine decarboxylase silencing as a potential strategy for targeting retinoblastoma.
Loss of dipeptidyl peptidase IV immunostaining discriminates malignant melanomas from deep penetrating nevi.
Suppressor of Zeste 12 homolog RNA interference inhibits retinoblastoma cell invasion.
Retinopathy of Prematurity
Pharmacologic and genetic manipulation of MMP-2 and -9 affects retinal neovascularization in rodent models of OIR.
Present-day conservative treatment retinopathy of prematurity.
Rhabdomyolysis
Mitochondria-Associated Matrix Metalloproteinases 2 and 9 in Acute Renal Pathologies.
Rhabdomyosarcoma
Coexpression of glucose transporter 1 and matrix metalloproteinase-2 in human cancers.
Fibronectin-induced COX-2 mediates MMP-2 expression and invasiveness of rhabdomyosarcoma.
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in paediatric tumour cells. Effects of tumour cell proliferation modulators on gelatinolytic activity.
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines.
Vasculogenic mimicry is a major feature and novel predictor of poor prognosis in patients with orbital rhabdomyosarcoma.
Rheumatic Diseases
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Rhinitis
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Increased expression of matrix metalloproteinase-2 in nasal polyps.
Rhinitis, Allergic
Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Chronic Rhinosinusitis With Nasal Polyps: Etiopathogenesis and Recurrence.
Nonasthmatic nasal polyposis patients with allergy exhibit greater epithelial MMP positivity.
Suppression of matrix metalloproteinase production in nasal fibroblasts by tranilast, an antiallergic agent, in vitro.
Rickets
Expression of chicken 75-kDa gelatinase B-like enzyme in perivascular chondrocytes suggests its role in vascularization of the growth plate.
Expression of matrix metalloproteinases during vascularization and ossification of normal and impaired avian growth plate.
Rosacea
Tear fluid gelatinase B activity correlates with IL-1alpha concentration and fluorescein clearance in ocular rosacea.
Salivary Gland Neoplasms
The MMP-2 and MMP-9 promoter polymorphisms and susceptibility to salivary gland cancer.
Sarcoglycanopathies
Cleavage of ?-dystroglycan occurs in sarcoglycan-deficient skeletal muscle without MMP-2 and MMP-9.
Sarcoidosis
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Matrix metalloproteinases and their tissue inhibitors in the lesions of cardiac and pulmonary sarcoidosis: an immunohistochemical study.
Metalloproteinases MMP-9, MMP-2 and their tissue inhibitors TIMP-1, TIMP-2 in peripheral transbronchial lung biopsies of patients with sarcoidosis.
Sarcoidosis, Pulmonary
Increased production of matrix metalloproteinase-2 in alveolar macrophages and regulation by interleukin-10 in patients with acute pulmonary sarcoidosis.
Sarcoma
A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas.
CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts.
Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts.
Emmprin, released as a microvesicle in epithelioid sarcoma, interacts with fibroblasts.
Enzymatic processing of collagen IV by MMP-2 (gelatinase A) affects neutrophil migration and it is modulated by extracatalytic domains.
Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines.
Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma.
Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysis.
Gelatinase and inhibitor expression in soft tissue sarcomas: lack of correlation with distant metastasis.
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors.
Local activity of matrix metalloproteinases in a case of botryoid sarcoma.
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Matrix metalloproteinase-2 and -9 involvement in canine tumors.
Papers to appear in forthcoming issues
PIK3R3, part of the regulatory domain of PI3K, is upregulated in sarcoma stem-like cells and promotes invasion, migration, and chemotherapy resistance.
Proteolytic enzymes in tumor metastasis. II. Collagenase type IV activity in subcellular fractions of cloned tumor cell populations.
Quercetin inhibits migration and invasion of SAS human oral cancer cells through inhibition of NF-?B and matrix metalloproteinase-2/-9 signaling pathways.
Regulation of gelatinase production and invasiveness by organ-specific fibroblasts in high- and low-metastatic clones from murine RCT sarcoma.
Significance of serum type IV collagenolytic activities and gelatinase levels for detection of metastasis in murine RCT sarcoma.
Synthetic emmprin peptides inhibit tumor cell-fibroblast interaction-stimulated upregulation of MMP-2 and tumor cell invasion.
SZ-117, a monoclonal antibody against matrix metalloproteinase-2 inhibits tumor cell-mediated angiogenesis.
The effect of microRNA-330 replacement on inhibition of growth and migration in renal cancer cells.
The role of angiocidin in sarcomas.
Sarcoma 180
Differential inductions of matrix metalloproteinase-2 and -9 in host tissues during the growth of ascitic sarcoma 180 cells in mice.
Sarcoma, Avian
Cloning of a 72 kDa matrix metalloproteinase (gelatinase) from chicken embryo fibroblasts using gene family PCR: expression of the gelatinase increases upon malignant transformation.
Cloning, expression, and characterization of chicken tissue inhibitor of metalloproteinase-2 (TIMP-2) in normal and transformed chicken embryo fibroblasts.
Native TIMP-free 70 kDa progelatinase (MMP-2) secreted at elevated levels by RSV transformed fibroblasts.
Resolution of TIMP-free and TIMP-complexed 70kDa progelatinase from culture medium of Rous sarcoma virus-transformed chicken embryo fibroblasts.
Sarcoma, Endometrial Stromal
Expression of metalloproteinases endometrial stromal sarcoma: immunohistochemical study using image analysis.
Papers to appear in forthcoming issues
Sarcoma, Ewing
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
Sarcoma, Kaposi
Angiogenic potential in vivo by Kaposi's sarcoma cell-free supernatants and HIV-1 tat product: inhibition of KS-like lesions by tissue inhibitor of metalloproteinase-2.
Sarcoma, Myeloid
A possible role of 92 kDa type IV collagenase in the extramedullary tumor formation in leukemia.
Sarcoma, Synovial
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
In vitro modulation of MMP-2 and MMP-9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors.
Matrix metalloproteinase-2 expression correlates with morphological and immunohistochemical epithelial characteristics in synovial sarcoma.
Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines.
[Correlation between matrix metalloproteinases-2 and tissue inhibitor of metalloproteinase-2 expression, metastatic potential and tumor angiogenesis in synovial sarcoma and its prognostic significance]
Schistosomiasis
Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
[Expression of matrix metalloproteinase 2 and 9 in liver tissue of patients with schistosomiasis japonica]
Schistosomiasis japonica
[Expression of matrix metalloproteinase 2 and 9 in liver tissue of patients with schistosomiasis japonica]
Scleroderma, Localized
[Systemic sclerosis and scleroderma circumscripta--disturbances of selected serum parameters which are responsible for vascular changes and CD34 expression in involved skin]
Scleroderma, Systemic
Gene expression of types I and III collagen, decorin, matrix metalloproteinases and tissue inhibitors of metalloproteinases in skin fibroblasts from patients with systemic sclerosis.
Increased gelatinase activity in systemic sclerosis dermal fibroblast cultures with unaltered gelatinase A mRNA expression.
Scoliosis
A Promoter Polymorphism of Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Gene Is Associated With Severity of Thoracic Adolescent Idiopathic Scoliosis.
[Association between tissue inhibitor of metalloproteinase-2 gene polymorphism and adolescent idiopathic thoracic scoliosis]
Seizures
Antidepressant treatments regulate matrix metalloproteinases-2 and -9 (MMP-2/MMP-9) and tissue inhibitors of the metalloproteinases (TIMPS 1-4) in the adult rat hippocampus.
Matrix metalloproteinase 9 regulates cell death following pilocarpine-induced seizures in the developing brain.
Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy.
Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations.
Regional and differential expression of gelatinases in rat brain after systemic kainic acid or bicuculline administration.
Seminoma
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor through Activation of MMP-2.
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]
Sepsis
Baicalein inhibits HMGB1 release and MMP-2/-9 expression in lipopolysaccharide-induced cardiac hypertrophy.
Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats.
Investigation of the effect of melatonin administration on inflammatory mediators; MMP-2, TGF-? and VEGF levels in rats with sepsis.
Matrix metalloproteinase inhibitors prevent sepsis-induced refractoriness to vasoconstrictors in the cecal ligation and puncture model in rats.
Matrix Metalloproteinase-2 and Metalloproteinase-9 Activities are Associated with Blood-Brain Barrier Dysfunction in an Animal Model of Severe Sepsis.
Matrix- metalloproteinase -2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis.
Matrix-metalloproteinases and their inhibitors are elevated in severe sepsis: prognostic value of TIMP-1 in severe sepsis.
Modulation of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in sepsis.
Plasma Neutrophil Gelatinase Associated Lipocalin Diagnosed Acute Kidney Injury in Patients With Systemic Inflammatory Disease And Sepsis.
Serum Neutrophil Gelatinase Associated Lipocalin (NGAL) Outperforms Serum Creatinine in Detecting Sepsis-Induced Acute Kidney Injury, Experiments on Bilateral Nephrectomy and Bilateral Ureter Obstruction Mouse Models.
Urinary neutrophil gelatinase associated lipocalin identifies neonates with high probability of sepsis.
Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis.
Urinary [TIMP-2]?×?[IGFBP7] and serum procalcitonin to predict and assess the risk for short-term outcomes in septic and non-septic critically ill patients.
Use of biomarkers in pediatric sepsis: literature review.
Severe Dengue
MMP cellular responses to dengue virus infection-induced vascular leakage.
Shock, Septic
Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature.
Gelatinase B deficiency protects against endotoxin shock.
Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis.
Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock.
Matrix metalloproteinases and TIMP in acute respiratory distress syndrome.
Targeting neutrophil collagenase/matrix metalloproteinase-8 and gelatinase B/matrix metalloproteinase-9 with a peptidomimetic inhibitor protects against endotoxin shock.
Sialadenitis
Extracellular matrix molecules in chronic obstructive sialadenitis: an immunocytochemical and Western blot investigation.
Silicosis
Expression and localization of TIMP-1, TIMP-2, MMP-13, MMP-2, and MMP-9 in early and advanced experimental lung silicosis.
Serum concentrations of Krebs von den Lungen-6, surfactant protein D, and matrix metalloproteinase-2 as diagnostic biomarkers in patients with asbestosis and silicosis: a case-control study.
[Relationship between genetic polymorphisms of matrix metalloproteinase-2 and -3 and susceptibility to silicosis].
[The discriminant analysis of the silicosis's induction on cytokines in phlegm and combined multi-markers].
Sinusitis
Increased expression of matrix metalloproteinase-2 in nasal polyps.
Skin Diseases
Cytokine and Chemokine Profile in Amicrobial Pustulosis of the Folds: Evidence for Autoinflammation.
Demonstration of 72-kDa and 92-kDa forms of type IV collagenase in human skin: variable expression in various blistering diseases, induction during re-epithelialization, and decrease by topical glucocorticoids.
Skin Neoplasms
Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression.
Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin via posttranslational mechanisms.
Plant derived coumestrol phytochemical targets human skin carcinoma cells by inducing mitochondrial-mediated apoptosis, cell cycle arrest, inhibition of cell migration and invasion and modulation of m-TOR/PI3K/AKT signalling pathway.
[VALUE OF METALPROTEINASES OF BLOOD IN PATHOGENESIS OF EPITELIAL SKIN TUMORS AND THE POSSIBILITY OF THEIR SURGICAL CORRECTION].
Skin Ulcer
Ectopic localization of matrix metalloproteinase-9 in chronic cutaneous wounds.
Sleep Apnea, Obstructive
Association between plasma neutrophil gelatinase associated lipocalin level and obstructive sleep apnea or nocturnal intermittent hypoxia.
Functional polymorphisms in the promoter region of MMP-2 and MMP-9 and susceptibility to obstructive sleep apnea.
Serum matrix metalloproteinase-2 as a predictor of level of hypoxemia and severity of obstructive sleep apnea.
Sleep Initiation and Maintenance Disorders
Inflammatory Biomarkers, Hematopoietic Stem Cells, and Symptoms in Breast Cancer Patients Undergoing Adjuvant Radiation Therapy.
Small Cell Lung Carcinoma
Absence of CD9 enhances adhesion-dependent morphologic differentiation, survival, and matrix metalloproteinase-2 production in small cell lung cancer cells.
Gelatin-degrading type IV collagenase isolated from human small cell lung cancer.
Smear Layer
Tetracycline at subcytotoxic levels inhibits matrix metalloproteinase-2 and -9 but does not remove the smear layer.
Smooth Muscle Tumor
Expression of matrix metalloproteinases in patients with uterine smooth muscle tumors: an immunohistochemical analysis of MMP-1 and MMP-2 protein expression in leiomyoma, uterine smooth muscle tumor of uncertain malignant potential, and leiomyosarcoma.
Soft Tissue Infections
Human Neutrophil Granule Exocytosis in Response to Mycobacterium smegmatis.
Soft Tissue Neoplasms
Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of the extremities.
Solitary Fibrous Tumors
Expression of CD44 and MMP-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors.
Spinal Cord Diseases
Immunohistochemical Profile of NF-?B/p50, NF-?B/p65, MMP-9, MMP-2 and u-PA in Experimental Cervical Spondylotic Myelopathy.
Spinal Cord Injuries
A nutrient mixture reduces the expression of matrix metalloproteinases in an animal model of spinal cord injury by modulating matrix metalloproteinase-2 and matrix metalloproteinase-9 promoter activities.
Activation of matrix metalloproteinases-9 after photothrombotic spinal cord injury model in rats.
Downregulation of Matrix Metalloproteinases 2 and 9 is Involved in the Protective Effect of Trehalose on Spinal Cord Injury.
Effects of hyperbaric oxygen on MMP-2 and MMP-9 expression and spinal cord edema after spinal cord injury.
Effects of hyperbaric oxygen on MMP-2 and MMP-9 expressions and spinal cord edema after spinal cord injury.
Fluoxetine inhibits matrix metalloprotease activation and prevents disruption of blood-spinal cord barrier after spinal cord injury.
Human umbilical cord blood stem cells upregulate matrix metalloproteinase-2 in rats after spinal cord injury.
Inhibition of MMP2/MMP9 after spinal cord trauma reduces apoptosis.
Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury.
Matrix metalloproteinases: potential therapeutic target in spinal cord injury.
Melatonin improves functional outcome via inhibition of matrix metalloproteinases-9 after photothrombotic spinal cord injury in rats.
Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier.
Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury.
Spinal Dysraphism
Urinary TIMP-2 and MMP-2 are significantly associated with poor bladder compliance in adult patients with spina bifida.
Spinal Stenosis
The increased expression of matrix metalloproteinases associated with elastin degradation and fibrosis of the ligamentum flavum in patients with lumbar spinal stenosis.
Spondylitis, Ankylosing
MMP-2 silencing reduces the osteogenic transformation of fibroblasts by inhibiting the activation of the BMP/Smad pathway in ankylosing spondylitis.
MMP-2, TNF-? and NLRP1 polymorphisms in Chinese patients with ankylosing spondylitis and rheumatoid arthritis.
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Squamous Cell Carcinoma of Head and Neck
Activation of matrix metalloproteinase-2 in head and neck squamous cell carcinoma: studies of clinical samples and in vitro cell lines co-cultured with fibroblasts.
Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.
Activation of Toll-Like Receptor-9 Promotes Cellular Migration via Up-Regulating MMP-2 Expression in Oral Squamous Cell Carcinoma.
Alpha-mangostin suppresses MMP-2 and MMP-9 expression in head and neck squamous carcinoma cells.
Analysis of expression of matrix metalloproteinases-2 and -9 in hypopharyngeal squamous cell carcinoma by in situ hybridization.
Anti-cancer Effect of 20(S)-Ginsenoside-Rh2 on Oral Squamous Cell Carcinoma Cells via the Decrease in ROS and Downregulation of MMP-2 and VEGF.
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Antimetastatic potentials of salvianolic acid A on oral squamous cell carcinoma by targeting MMP-2 and the c-Raf/MEK/ERK pathway.
Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2.
Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.
Clinical significance of expression of membrane type 1 matrix metalloproteinase and matrix metalloproteinase-2 in human head and neck squamous cell carcinoma.
Combination of ACY-241 and JQ1 Synergistically Suppresses Metastasis of HNSCC via Regulation of MMP-2 and MMP-9.
Correlation of matrix metalloproteinase-2, -9, tissue inhibitor-1 of matrix metalloproteinase and CD44 variant 6 in head and neck cancer metastasis.
Curcumin Inhibits Invasiveness and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Through Reducing Matrix Metalloproteinase 2, 9 and Modulating p53-E-Cadherin Pathway.
Cytokine regulation of gelatinase production by head and neck squamous cell carcinoma: the role of tumor necrosis factor-alpha.
Differential expression of c-jun and c-fos mRNAs in squamous cell carcinoma of the head and neck: associations with uPA, gelatinase B, and matrilysin mRNAs.
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
Down-regulation of MMP-2 expression due to inhibition of receptor tyrosine kinases by imatinib and carboplatin in HNSCC.
Downregulation of miR-21 regulates MMP-2 expression and suppress migration of Laryngeal squamous cell carcinoma.
E1AF expression is closely correlated with malignant phenotype of tongue squamous cell carcinoma through activation of MT1-MMP gene promoters.
Effects of cigarette smoke condensate on oral squamous cell carcinoma cells.
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas: implications for lymph node metastasis.
Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells.
Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2.
Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-beta1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions.
Expression and clinical significance of matrix metalloproteinase-2 and matrix metalloproteinase-9 in oral squamous cell carcinoma.
Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck.
Expression of cyclooxygenase-2, vascular endothelial growth factor and matrix metalloproteinase-2 in patients with primary laryngeal carcinoma: a tissue microarray study.
Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity.
Expression of matrix metalloproteinase 1, matrix metalloproteinase 2, and matrix metalloproteinase 9 in carcinoma of the head and neck.
Expression of matrix metalloproteinase 2 and its tissue inhibitor in oral squamous cell carcinoma.
Expression of matrix metalloproteinase-2 and -9 in oral squamous cell carcinomas with regard to the metastatic potential.
Expression of matrix metalloproteinase-2 related to lymph node metastasis of oral squamous cell carcinoma. A clinicopathologic study.
Expression of matrix metalloproteinases (MMP-2 and MMP-9) in recurrent respiratory papillomas and laryngeal carcinoma: clinical and morphological parallels.
Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo.
Fibroblasts and extracellular matrix differently modulate MMP activation by primary and metastatic head and neck cancer cells.
Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis.
Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
Human head and neck squamous cell carcinoma cells are both targets and effectors for the angiogenic cytokine, VEGF.
Human neutrophil peptide-1 affects matrix metalloproteinase-2, -8 and -9 secretions of oral squamous cell carcinoma cell lines in vitro.
Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma.
Immunohistochemical expression of MMP-2 and MMP-8 in oral squamous cell carcinoma.
Increased expression and activation of matrix metalloproteinase-2 (MMP-2) in O-1N: hamster oral squamous cell carcinoma with high potential lymph node metastasis.
Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.
Inhibition of cervical lymph node metastasis by marimastat (BB-2516) in an orthotopic oral squamous cell carcinoma implantation model.
Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44.
Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation.
Inhibition of head and neck squamous cell carcinoma growth and invasion by the calcium influx inhibitor carboxyamido-triazole.
Inhibition of matrix metalloproteinase-2 modulates malignant behaviour of oral squamous cell carcinoma cells.
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.
Leptin acts on neoplastic behavior and expression levels of genes related to hypoxia, angiogenesis, and invasiveness in oral squamous cell carcinoma.
Levels of neutrophil gelatinase-assosciated lipocalin in patients with head and neck squamous cell carcinoma in Indian population from Haryana state.
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.
Matrix metalloproteinase-2 and -9 activities correlate with the disease-free survival of oral squamous cell carcinoma patients.
Matrix metalloproteinases (MMPs) and inhibitor of metalloproteinases (TIMP) mRNA and protein expression in laryngeal squamous cell carcinoma.
Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer.
May High MMP-2 and TIMP-2 Expressions Increase or Decrease the Aggressivity of Oral Cancer?
Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma.
Metalloproteinases and their inhibitors: Influence on tumor invasiveness and metastasis formation in head and neck squamous cell carcinomas.
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus.
Modulation of cell growth and matrix metalloproteinase-2 activation of oral squamous cell carcinoma as a function of culture condition with type I collagen.
Molecular pathways involved in crosstalk between cancer cells, osteoblasts and osteoclasts in the invasion of bone by oral squamous cell carcinoma.
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Oral and IV Dosages of Doxorubicin-Methotrexate loaded- Nanoparticles Inhibit Progression of Oral Cancer by Down- Regulation of Matrix Methaloproteinase 2 Expression in Vivo.
Oral submucous fibrosis stimulates invasion and epithelial-mesenchymal transition in oral squamous cell carcinoma by activating MMP-2 and IGF-IR.
Osteoactivin Regulates Head and Neck Squamous Cell Carcinoma Invasion by Modulating Matrix Metalloproteases.
Overexpression of MMP-2 in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.
Participation of fibroblasts in MMP-2 binding and activation on the surface of oral squamous cell carcinoma cells.
Prediction of metastasis in oral squamous cell carcinoma through phenotypic evaluation and gene expression of E-cadherin, ?-catenin, matrix metalloproteinase-2, and matrix metalloproteinase-9 biomarkers with clinical correlation.
Production of matrix metalloproteinase 2 (gelatinase/type IV collagenase) and 3 (stromelysin) by cultured oral squamous cell carcinoma.
Prognostic molecular markers in head and neck squamous cell carcinoma in a New Zealand population: matrix metalloproteinase-2 and sialyl Lewis x antigen.
Prognostic significance of CXCR-4 expression in oral squamous cell carcinoma.
Prognostic value of matrix metalloproteinases in oral squamous cell carcinoma.
Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas.
Quercetin suppresses cellular migration and invasion in human head and neck squamous cell carcinoma (HNSCC).
Regulatory effect of MiR103 on proliferation, EMT and invasion of oral squamous carcinoma cell through SALL4.
Relationship between the Expression of Matrix Metalloproteinase and Clinicopathologic Features in Oral Squamous Cell Carcinoma.
Role of functional polymorphism of matrix metalloproteinase-2 (-1306 C/T and -168 G/T) and MMP-9 (-1562 C/T) promoter in oral submucous fibrosis and head and neck squamous cell carcinoma in an Indian population.
Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro.
Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.
S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells.
Serum Level of Matrix Metalloproteinase-2 and -9 in Patients with Laryngeal Squamous Cell Carcinoma and Clinical Significance.
Serum levels of matrix metalloproteinase-2 and -9 in patients with head and neck squamous cell carcinoma.
Skp2 Regulates the Expression of MMP-2 and MMP-9, and Enhances the Invasion Potential of Oral Squamous Cell Carcinoma.
Strong association of the tissue inhibitor of metalloproteinase-2 polymorphism with an increased risk of oral squamous cell carcinoma in Europeans.
The immunohistochemical characterization of MMP-2, MMP-10, TIMP-1, TIMP-2, and podoplanin in oral squamous cell carcinoma.
The role of matrix metalloproteinases in squamous cell carcinomas of the head and neck.
The upregulated ?-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition.
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.
Tissue and circulating immunoreactive protein for MMP-2 and TIMP-2 in head and neck squamous cell carcinoma-tissue immunoreactivity predicts aggressive clinical course.
Tumor-stroma interactions influence cytokine expression and matrix metalloproteinase activities in paired primary and metastatic head and neck cancer cells.
[Expression and clinical significance of matrix metalloproteinase-2 in laryngeal squamous cell carcinoma]
[Expressions and significances of CD147, OPN and MMP-2 in oral squamous cell carcinoma].
Squamous Intraepithelial Lesions of the Cervix
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
ST Elevation Myocardial Infarction
Alteplase treatment affects circulating matrix metalloproteinase concentrations in patients with ST segment elevation acute myocardial infarction.
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction.
Expressions and clinical significance of factors related to acute coronary syndrome.
Serum and Echocardiographic Markers May Synergistically Predict Adverse Cardiac Remodeling after ST-Segment Elevation Myocardial Infarction in Patients with Preserved Ejection Fraction.
Staphylococcal Infections
Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines.
Starvation
Molecular mechanisms involved in the protective effect of pituitary adenylate cyclase-activating polypeptide in an in vitro model of amyotrophic lateral sclerosis.
Status Epilepticus
Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy.
Stevens-Johnson Syndrome
Neutrophil Collagenase, Gelatinase, and Myeloperoxidase in Tears of Patients with Stevens-Johnson Syndrome and Ocular Cicatricial Pemphigoid.
Possible involvement of gelatinase A (MMP2) and gelatinase B (MMP9) in toxic epidermal necrolysis or Stevens-Johnson syndrome.
Stomach Neoplasms
A small interfering RNA targeting osteopontin as gastric cancer therapeutics.
AA-PMe, a novel asiatic acid derivative, induces apoptosis and suppresses proliferation, migration, and invasion of gastric cancer cells.
Anti-cancer activity of DHA on gastric cancer-an in vitro and in vivo study.
Anti-metastatic activity of fangchinoline in human gastric cancer AGS cells.
Anti-tumor effects of mfn2 in gastric cancer.
Arsenic trioxide inhibits invasion/migration in SGC-7901 cells by activating the reactive oxygen species-dependent cyclooxygenase-2/matrix metalloproteinase-2 pathway.
Baicalein inhibits the invasion of gastric cancer cells by suppressing the activity of the p38 signaling pathway.
Bcl-w promotes gastric cancer cell invasion by inducing matrix metalloproteinase-2 expression via phosphoinositide 3-kinase, Akt, and Sp1.
Blockade of CXCR6 reduces invasive potential of gastric cancer cells through inhibition of AKT signaling.
CDH17 alters MMP-2 expression via canonical NF-?B signalling in human gastric cancer.
Changes of histology and expression of MMP-2 and nm23-H1 in primary and metastatic gastric cancer.
Circular RNA 0000096 affects cell growth and migration in gastric cancer.
Claudin-4 expression in gastric cancer cells enhances the invasion and is associated with the increased level of matrix metalloproteinase-2 and -9 expression.
Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer.
Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer.
Clinical Significance of Matrix Metalloproteinases in Blood Plasma of Patients with Gastric Cancer.
Clinical significance of serum levels of matrix metalloproteinase 2 (MMP-2) and its tissue inhibitor (TIMP-2) in gastric cancer.
Clinical significance of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric cancer.
Clinicopathological significance of E-cadherin, VEGF, and MMPs in gastric cancer.
Clinicopathological significance of MMP-2 and its specific inhibitor TIMP-2 in gastric cancer.
Clinicopathological significance of MMP-2 and TIMP-2 genotypes in gastric cancer.
Co-evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance.
Correlations of MMP-2 and TIMP-2 gene polymorphisms with the risk and prognosis of gastric cancer.
CXCL10/CXCR3 axis promotes the invasion of gastric cancer via PI3K/AKT pathway-dependent MMPs production.
Defining the invasive phenotype of proximal gastric cancer cells.
Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity.
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1?/ TGF-?.
Downregulation of CD147 by chitooligosaccharide inhibits MMP-2 expression and suppresses the metastatic potential of human gastric cancer.
Downregulation of FKBP14 by RNA interference inhibits the proliferation, adhesion and invasion of gastric cancer cells.
Downregulation of NDRG1 promotes invasion of human gastric cancer AGS cells through MMP-2.
Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer.
Effect of a synthetic cannabinoid agonist on the proliferation and invasion of gastric cancer cells.
Effect of glutamine-enriched nutritional support on intestinal mucosal barrier function, MMP-2, MMP-9 and immune function in patients with advanced gastric cancer during perioperative chemotherapy.
Effect of hGC-MSCs from human gastric cancer tissue on cell proliferation, invasion and epithelial-mesenchymal transition in tumor tissue of gastric cancer tumor-bearing mice.
Effects of angiopoietin-1 on attachment and metastasis of human gastric cancer cell line BGC-823.
Effects of LY294002 on the invasiveness of human gastric cancer in vivo in nude mice.
Effects of Tiam 1 on Invasive Capacity of Gastric Cancer Cells in vitro and Underlying Mechanisms.
Elevated levels of serum and plasma metalloproteinases in patients with gastric cancer.
Erratum: Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP-2 and MMP-9 expression via the p38MAPK signaling pathway.
Expression and correlation of CD44v6, vascular endothelial growth factor, matrix metalloproteinase-2, and matrix metalloproteinase-9 in Krukenberg tumor.
Expression of collagenase-3 (matrix metalloproteinase-13) in human gastric cancer.
Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression.
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma.
Expression of MMP-7 and MT1-MMP in peritoneal dissemination of gastric cancer.
Expression of peroxisome proliferator-activated receptor g, E-cadherin and matrix metalloproteinases-2 in gastric carcinoma and lymph node metastases.
Expression of PI3K/AKT pathway in gastric cancer and its blockade suppresses tumor growth and metastasis.
Expression of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) as a prognostic indicator in gastric cancer.
Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma.
Expression of TRAP1 in gastric cancer tissue and its correlation with malignant biology.
Expression of Vav3 protein and its prognostic value in patients with gastric cancer.
Expression of Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis.
Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy.
Ginkgolic acid (GA) suppresses gastric cancer growth by inducing apoptosis and suppressing STAT3/JAK2 signaling regulated by ROS.
Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer.
High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer.
Immunoexpression of Metalloproteinases 2 and 14 and TIMP-2 Inhibitor in Main Types of Primary Gastric Carcinomas and Lymph Node Metastasis.
Inhibitory effect of siRNA-Annexin A7 on growth, migration, and invasion in BGC823 cells and gastric cancer xenograftsin nude mice.
Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas.
Invasion and metastases in gastric cancer: in vitro and in vivo models with clinical correlations.
JWA suppresses tumor angiogenesis via Sp1-activated MMP-2 and its prognostic significance in human gastric cancer.
Knockdown of RAGE inhibits growth and invasion of gastric cancer cells.
LOX inhibition downregulates MMP-2 and MMP-9 in gastric cancer tissues and cells.
Lymph Node Metastasis of Gastric Cancer Is Associated with the Interaction Between Poly (ADP-Ribose) Polymerase 1 and Matrix Metallopeptidase 2.
Lymph node micrometastasis and its correlation with MMP-2 expression in gastric carcinoma.
Matrix metalloproteinase 2 (MMP-2) and their tissue inhibitor 2 (TIMP-2) in gastric cancer patients.
Matrix metalloproteinase-2 is a consistent prognostic factor in gastric cancer.
Matrix metalloproteinases and their inhibitors in gastric cancer.
Melanoma differentiation-associated gene-7 suppresses human gastric cancer cell invasion and migration.
Melatonin inhibits lung metastasis of gastric cancer in vivo.
MicroRNA-133a functions as a tumor suppressor in gastric cancer.
MicroRNA-524-5p suppresses the growth and invasive abilities of gastric cancer cells.
MMP-2 as a putative biomarker for carcinomatosis in gastric cancer.
MMP-2 but not MMP-9 associated with COX-2 and survival in gastric cancer.
MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma.
mRNA Expression Analysis of E-Cadherin, VEGF, and MMPs in Gastric Cancer: a Pilot Study.
Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway.
Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms.
Omental adipocytes enhance the invasiveness of gastric cancer cells by oleic acid-induced activation of the PI3K-Akt signaling pathway.
Osteopontin promotes the progression of gastric cancer through the NF-?B pathway regulated by the MAPK and PI3K.
p21-activated protein kinase 1 induces the invasion of gastric cancer cells through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase-2.
Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways.
Polypeptide N-acetylgalactosaminyltransferase 2 regulates cellular metastasis-associated behavior in gastric cancer.
Prognostic relevance of MMP-2 (72-kD collagenase IV) in gastric cancer.
Propofol inhibits proliferation and accelerates apoptosis of human gastric cancer cells by regulation of microRNA-451 and MMP-2 expression.
Propranolol suppresses gastric cancer cell growth by regulating proliferation and apoptosis.
PTEN Gene Induces Cell Invasion and Migration via Regulating AKT/GSK-3?/?-Catenin Signaling Pathway in Human Gastric Cancer.
Reduced angiogenesis in peritoneal dissemination of gastric cancer through gelatinase inhibition.
Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer.
Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8.
Regulation of MMP-2 expression and activity by ?-1,3-N-acetylglucosaminyltransferase-8 in AGS gastric cancer cells.
Relationship between matrix metalloproteinase-2 mRNA expression and clinicopathological and urokinase-type plasminogen activator system parameters and prognosis in human gastric cancer.
Relationship between single-nucleotide polymorphism of matrix metalloproteinase-2 gene and colorectal cancer and gastric cancer susceptibility: a meta-analysis.
Secretory leukocyte protease inhibitor is associated with MMP-2 and MMP-9 to promote migration and invasion in SNU638 gastric cancer cells.
Serum levels of matrix metalloproteinase-2 and -9 and conventional tumor markers (CEA and CA 19-9) in patients with colorectal and gastric cancers.
Signaling components involved in Bcl-w-induced migration of gastric cancer cells.
Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP-2 and MMP-9 expression via the p38MAPK signaling pathway.
Similarities of in situ mRNA expression between gelatinase A (MMP-2) and type I procollagen in human gastrointestinal carcinoma: comparison with granulation tissue reaction.
SPARC is associated with gastric cancer progression and poor survival of patients.
Specificity Protein 1 Expression Contributes to Bcl-w-Induced Aggressiveness in Glioblastoma Multiforme.
Stomach Cancer: Interconnection between the Redox State, Activity of MMP-2, MMP-9 and Stage of Tumor Growth.
Study of the Relationship between MMP-2 and MMP-9 and Her2/neu Overexpression in Gastric Cancer: Clinico- Pathological Correlations.
Synergistic Beneficial Effect of Docosahexaenoic Acid (DHA) and Docetaxel on the Expression Level of Matrix Metalloproteinase-2 (MMP-2) and MicroRNA-106b in Gastric Cancer.
The anti-alcohol dependency drug disulfiram inhibits the viability and progression of gastric cancer cells by regulating the Wnt and NF-?B pathways.
The collagenase activities, interstitial collagenase and type IV collagenase, in human stomach cancer: with special reference to local spreading and lymph node metastasis.
The prognostic role of matrix metalloproteinase 2 in gastric cancer: a systematic review with meta-analysis.
The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer.
Tissue inhibitor of metalloproteinase-2 G-418C polymorphism is associated with an increased risk of gastric cancer in a Chinese population.
Tranilast (N-3,4-dimethoxycinamoyl anthranilic acid): a novel inhibitor of invasion-stimulating interaction between gastric cancer cells and orthotopic fibroblasts.
Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns.
ZBTB20 promotes cell migration and invasion of gastric cancer by inhibiting I?B? to induce NF-?B activation.
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.
[Association of functional polymorphisms in matrix metalloproteinase-2 (MMP-2) and MMP-9 genes with risk of gastric cancer in a Chinese population.]
[Comparative study of mRNA expression of E-cadherin and collagenase IV in early and advanced cancers]
[Effect of tumor-associated macrophages on invasion and metastasis of gastric cancer cells].
[Effects of dihydromyricetin on the migration and invasion of human gastric cancer MKN45 cells and its mechanism].
[Effects of FRZB on growth and metastasis of gastric cancer cell line SGC-7901]
[Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
[Inhibition of human gastric cancer metastasis by ocreotide in vitro and in vivo]
[Matrix metalloproteinase-2 and angiogenesis in gastric cancer]
[MMP-2 expression (type IV collagenase) in gastric cancer]
[The relation between integrin, type IV collagenase and extracellular matrix in invasion and metastasis of gastric carcinoma]
Stomach Ulcer
Curcumin regulates expression and activity of matrix metalloproteinases 9 and 2 during prevention and healing of indomethacin-induced gastric ulcer.
Doxycycline blocks gastric ulcer by regulating matrix metalloproteinase-2 activity and oxidative stress.
Effect of anthocyanins on expression of matrix metalloproteinase-2 in naproxen-induced gastric ulcers.
Effect of melatonin on secreted and induced matrix metalloproteinase-9 and -2 activity during prevention of indomethacin-induced gastric ulcer.
Matrix metalloproteinase-9 activity and expression is reduced by melatonin during prevention of ethanol-induced gastric ulcer in mice.
Matrix metalloproteinases 2 and 9 in indomethacin-induced rat gastric ulcer.
Melatonin promotes angiogenesis during protection and healing of indomethacin-induced gastric ulcer: role of matrix metaloproteinase-2.
Remodeling of extracellular matrix in gastric ulceration.
Spatial and temporal pattern of expression of interstitial collagenase, stromelysin/transin, gelatinase A, and TIMP-1 during experimental gastric ulcer healing.
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity.
[Role of Allelic Genes of Matrix Metalloproteinases and Their Tissue Inhibitors in the Peptic Ulcer Disease Development].
Stroke
A rapid and highly sensitive strain-effect graphene-based bio-sensor for the detection of stroke and cancer bio-markers.
Cardiac dysfunction in an animal model of neonatal asphyxia is associated with increased degradation of MLC1 by MMP-2.
Cardiac function, myocardial glutathione, and matrix metalloproteinase-2 levels in hypoxic newborn pigs reoxygenated by 21%, 50%, or 100% oxygen.
Complexity in differentiating truncated or matured forms of MMP-2 and MMP-9 by zymography in acute ischemic stroke induced rat brain tissues.
Decreased plasma decorin levels following acute ischemic stroke: correlation with MMP-2 and differential expression in TOAST subtypes.
Delayed Gelatinase Inhibition Induces Reticulon 4 Receptor Expression in the Peri-Infarct Cortex.
Different roles of matrix metalloproteinases-2 and -9 after human ischaemic stroke.
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
Engineering autoactivating forms of matrix metalloproteinase-9 and expression of the active enzyme in cultured cells and transgenic mouse brain.
Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke.
Hemorrhagic transformation after ischemic stroke in animals and humans.
Hyperthermia up-regulates matrix metalloproteinases and accelerates basement membrane degradation in experimental stroke.
Identification of novel blood biomarker panels to detect ischemic stroke in patients and their responsiveness to therapeutic intervention.
Increase in plasma matrix metalloproteinase-9 in acute stroke patients with thrombolysis failure.
Inhibition of HIF-1? Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia.
Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.
Intra-arterial bone marrow mononuclear cell transplantation correlates with GM-CSF, PDGF-BB, and MMP-2 serum levels in stroke patients: results from a clinical trial.
Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons.
Matrix metalloproteinase and cytokine profiles in monocytes over the course of stroke.
Matrix metalloproteinase-2 gene polymorphisms are associated with ischemic stroke in a Hainan population.
Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke.
Matrix metalloproteinases and their inhibitors in different acute stroke subtypes.
Matrix Metalloproteinases Are Associated With Increased Blood-Brain Barrier Opening in Vascular Cognitive Impairment.
Methylation in the matrix metalloproteinase-2 gene is associated with cerebral ischemic stroke.
MMP-2 and MMP-9 levels in peripheral blood after subarachnoid hemorrhage.
MMP-2 concentrations in stroke according to etiology: Adjusting for enzyme degradation in stored deep-frozen serum and other methodological pitfalls.
MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke.
Optical Interference-Free Surface-Enhanced Raman Scattering CO-Nanotags for Logical Multiplex Detection of Vascular Disease-Related Biomarkers.
Proteolytic cascade enzymes increase in focal cerebral ischemia in rat.
Reduced brain edema and matrix metalloproteinase (MMP) expression by pre-reperfusion infusion into ischemic territory in rat.
Reduction in levels of matrix metalloproteinases and increased expression of tissue inhibitor of metalloproteinase-2 in response to mild hypothermia therapy in experimental stroke.
Resveratrol improves delayed r-tPA treatment outcome by reducing MMPs.
Role of NADPH Oxidase-Induced Hypoxia-Induced Factor-1? Increase in Blood-Brain Barrier Disruption after 2-Hour Focal Ischemic Stroke in Rat.
Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier.
Selective water-soluble gelatinase inhibitor prodrugs.
Serum activity of matrix metalloproteinase-2 and -9 is increased in chronic post-stroke individuals: a cross-sectional exploratory study.
Single-nucleotide polymorphisms of MMP-2 gene in stroke subtypes.
Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression.
Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood-Brain Barrier Disruption after Ischemic Stroke.
True Effects or Bias? MMP-2 and MMP-9 Serum Concentrations after Acute Stroke.
Up-regulation of brain cytokines and metalloproteinases 1 and 2 contributes to neurological deficit and brain damage in transient ischemic stroke.
Variants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke.
White matter damage is associated with matrix metalloproteinases in vascular dementia.
Stroke, Lacunar
Different roles of matrix metalloproteinases-2 and -9 after human ischaemic stroke.
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Single-nucleotide polymorphisms of MMP-2 gene in stroke subtypes.
Subacute Sclerosing Panencephalitis
Response of extracellular matrix regulators in mouse lung after exposure to photons, protons and simulated solar particle event protons.
Subarachnoid Hemorrhage
MMP-2 and MMP-9 levels in peripheral blood after subarachnoid hemorrhage.
Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier.
[Role of acute alcohol poisoning and craniocerebral trauma in the mechanism of death caused by subarachnoid hemorrhage].
Subdural Effusion
[Role of matrix metalloproteinase in transformation of subdural effusion into chronic subdural hematoma]
Supranuclear Palsy, Progressive
Selective localization of gelatinase A, an enzyme degrading beta-amyloid protein, in white matter microglia and in Schwann cells.
Sweet Syndrome
Inflammatory cells, cytokines and matrix metalloproteinases in amicrobial pustulosis of the folds and other neutrophilic dermatoses.
Role of inflammatory cells, cytokines and matrix metalloproteinases in neutrophil-mediated skin diseases.
Synovitis
Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis.
Cadherin-11 involves in synovitis and increases the migratory and invasive capacity of fibroblast-like synoviocytes of osteoarthritis.
Changes in MMP-2 and -9 activity and MMP-8 reactivity after amphotericin B induced synovitis and treatment with bufexamac.
Gelatinase B in chronic synovitis: immunolocalization with a monoclonal antibody.
Quercetin: a potential natural drug for adjuvant treatment of rheumatoid arthritis.
Takayasu Arteritis
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Temporomandibular Joint Disorders
Correlation of molecular biomarker concentrations between synovial fluid and saliva of the patients with temporomandibular disorders.
Is the incidence of temporomandibular disorder increased in polycystic ovary syndrome?
MMPs in tissues retrieved during surgery from patients with TMJ disorders relate to pain more than to radiological damage score.
Tendinopathy
Additional evidence supports association of common genetic variants in MMP3 and TIMP2 with increased risk of chronic Achilles tendinopathy susceptibility.
Trigger finger, tendinosis, and intratendinous gene expression.
Tenosynovitis
Production of cytokines, vascular endothelial growth factor, matrix metalloproteinases, and tissue inhibitor of metalloproteinases 1 by tenosynovium demonstrates its potential for tendon destruction in rheumatoid arthritis.
Teratocarcinoma
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Testicular Neoplasms
Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.
Inhibitory effects of a nutrient mixture on human testicular cancer cell line NT 2/DT matrigel invasion and MMP activity.
Nuclear Localization of PTTG1 Promotes Migration and Invasion of Seminoma Tumor through Activation of MMP-2.
Thrombocytopenia
Inhaled nitric oxide inhibits the release of matrix metalloproteinase-2, but not platelet activation, during extracorporeal membrane oxygenation in adult rabbits.
Thrombocytosis
Importance of plasma matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinase (TIMP) in development of fibrosis in agnogenic myeloid metaplasia.
Thrombophlebitis
Matrix metalloproteinases in the vein wall.
Thrombosis
A novel mechanism regulating human platelet activation by MMP-2-mediated PAR1 biased signaling.
Contribution of the TNF-? (Tumor Necrosis Factor-?)-TNF-Rp55 (Tumor Necrosis Factor Receptor p55) Axis in the Resolution of Venous Thrombus.
Deep vein thrombosis resolution is modulated by monocyte CXCR2-mediated activity in a mouse model.
Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm.
Differential transcriptional activation of matrix metalloproteinase-2 and membrane type-1 matrix metalloproteinase by experimental deep venous thrombosis and thrombin.
Expression changes and roles of matrix metalloproteinases in a rat model of traumatic deep vein thrombosis.
Granulocytes in coronary thrombus evolution after myocardial infarction - time-dependent changes in expression of matrix metalloproteinases.
Higher levels of plasma matrix metalloproteinase-2 are associated with a significantly increased risk of arterial thrombosis in patients with the antiphospholipid syndrome.
Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro.
Immunohistochemical detection of MMP-2 and MMP-9 in a stasis-induced deep vein thrombosis model and its application to thrombus age estimation.
Increased expression of 72-kd type IV collagenase (MMP-2) in human aortic atherosclerotic lesions.
Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms.
Losartan and captopril treatment rescue normal thrombus formation in microfibril associated glycoprotein-1 (MAGP1) deficient mice.
Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.
Matrix metalloproteinase-2 enhances platelet deposition on collagen under flow conditions.
Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix.
MR imaging of iron phagocytosis in intraluminal thrombi of abdominal aortic aneurysms in humans.
Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice.
Overexpression of transforming growth factor-beta1 stabilizes already-formed aortic aneurysms: a first approach to induction of functional healing by endovascular gene therapy.
Plasmin inhibition increases MMP-9 activity and decreases vein wall stiffness during venous thrombosis resolution.
Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity.
Resistin Promotes Thrombosis in Rats with Deep Vein Thrombosis via Up-Regulating MMP-2, MMP-9, and PAI-1.
Spatial differences of matrix metalloproteinase-2 and matrix metalloproteinase-9 within abdominal aortic aneurysm wall and intraluminal thrombus.
The intraluminal thrombus as a source of proteolytic activity.
Up-regulation of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase were coupled with that of type I procollagen in granulation tissue response after the onset of aortic dissection.
Vein wall remodeling after deep vein thrombosis involves matrix metalloproteinases and late fibrosis in a mouse model.
Thrombotic Microangiopathies
Loss of diacylglycerol kinase ? causes thrombotic microangiopathy by impairing endothelial VEGFA signaling.
Thymoma
Activation of matrix metalloproteinase-2 is correlated with invasiveness in thymic epithelial tumors.
Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.
Cetyltrimethylammonium Bromide Suppresses the Migration and Invasion of Hepatic Mahlavu Cells by Modulating Fibroblast Growth Factor Signaling.
Expression of matrix metalloproteinases 2 and 7 in tumor cells correlates with the World Health Organization classification subtype and clinical stage of thymic epithelial tumors.
Increased expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 is correlated with poor prognostic variables in patients with thymic epithelial tumors.
[Correlation between MMP-2 activation and MT1-MMP mRNA expression in thymic epithelial tumors]
[Expression of PTEN, matrix metaloproteinases 2 and 9 in thymomas]
Thyroid Cancer, Papillary
Bone sialoprotein, matrix metalloproteinase 2, and alpha(v)beta3 integrin in osteotropic cancer cell invasion.
Clinical value of matrix metalloproteinase-2 and -9 in ultrasound-guided radiofrequency ablation treatment for papillary thyroid carcinoma.
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Correlations between papillary thyroid cancer and peripheral blood levels of matrix metalloproteinase-2, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, and tissue inhibitor of metalloproteinase-2.
Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.
Estrogen receptor subtype expression and regulation is altered in papillary thyroid cancer after menopause.
Expression and function of CXCL12/CXCR4/CXCR7 in thyroid cancer.
Expression of COX-2 is increased with age in papillary thyroid cancer.
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Expression of Receptors for Pituitary-Type Growth Hormone-Releasing Hormone (pGHRH-R) in Human Papillary Thyroid Cancer Cells: Effects of GHRH Antagonists on Matrix Metalloproteinase-2.
Immunohistochemical levels of matrix metalloproteinase-2 and CD44 variant 6 protein in the diagnosis and lateral cervical lymph node metastasis of papillary thyroid carcinoma.
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Protein expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in papillary thyroid carcinomas.
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Serum MMP-2 as a potential predictive marker for papillary thyroid carcinoma.
Single nucleotide polymorphisms in matrix metalloproteinase 2 (MMP2) enhance BRAFV600E mutation-mediated oncogenicity and invasiveness of papillary thyroid cancer cells.
The Synergistic Effects of Celecoxib and Sodium Valproate on Apoptosis and Invasiveness Behavior of Papillary Thyroid Cancer Cell Line In-vitro.
[Correlations of serous levels of matrix metalloproteinases (MMP-2 and MMP-9) to invasion and metastasis of papillary thyroid carcinoma]
[Expression of matrix metalloproteinases 2 and 9 and their tissue inhibitors 1 and 2 in papillary thyroid cancer: an association with the clinical, morphological and ultrastructural characteristics of a tumor].
Thyroid Diseases
MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma.
Thyroid Neoplasms
Clinicopathologic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma.
Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study.
Concentration of metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in the serum of patients with benign and malignant thyroid tumours treated surgically.
Distribution of the 72-kd type IV collagenase in nonneoplastic and neoplastic thyroid tissue.
Down-regulation of matrix metalloproteinase-7 inhibits metastasis of human anaplastic thyroid cancer cell line.
Enigma Plays Roles in Survival of Thyroid Carcinoma Cells through PI3K/AKT Signaling and Survivin.
Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer.
Expression and function of CXCL12/CXCR4/CXCR7 in thyroid cancer.
Expression and role of matrix metalloproteinases MMP-2 and MMP-9 in human spinal column tumors.
Expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in medullary thyroid carcinoma: prognostic implications.
Expression of matrix metalloproteinase-2 and its tissue inhibitor-2 in fetal and neoplastic thyroid tissue and their significance as diagnostic and prognostic markers in papillary carcinoma.
Ginsenoside Rg3 Inhibition of Thyroid Cancer Metastasis Is Associated with Alternation of Actin Skeleton.
Increased expression of matrix metalloproteinase-2: a diagnostic marker but not prognostic marker of papillary thyroid carcinoma.
Increased plasminogen activator and type IV collagenase activity in invasive follicular thyroid carcinoma cells.
Long non-coding RNA LIFR-AS1 regulates the proliferation, migration and invasion of human thyroid cancer cells.
Matrix metalloproteinases, tissue inhibitors of matrix metalloproteinases and angiogenic cytokines in peripheral blood of patients with thyroid cancer.
MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma.
mRNA levels of membrane-type 1 matrix metalloproteinase (MT1-MMP), MMP-2, and MMP-9 and of their inhibitors TIMP-2 and TIMP-3 in normal thyrocytes and thyroid carcinoma cell lines.
PLK1 gene suppresses cell invasion of undifferentiated thyroid carcinoma through the inhibition of CD44v6, MMP-2 and MMP-9.
Reduced tissue inhibitor of metalloproteinase-2 expression is associated with advanced medullary thyroid carcinoma.
Relationship between protein expression of VEGF-C, MMP-2 and lymph node metastasis in papillary thyroid cancer.
Shikonin Inhibits Thyroid Cancer Cell Growth and Invasiveness through Targeting Major Signaling Pathways.
Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway.
Synergistic cytotoxicity of the dipeptidyl peptidase-IV inhibitor gemigliptin with metformin in thyroid carcinoma cells.
TGF-?1 induces HMGA1 expression: The role of HMGA1 in thyroid cancer proliferation and invasion.
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
[Effect of Nifuroxazide on Proliferation, Migration, and Invasion of Thyroid Papillary Carcinoma Cells].
[Study of type I and IV collagenase activity in human thyroid diseases]
Thyroid Nodule
Ratio of metalloproteinase 2 to tissue inhibitor of metalloproteinase 2 in medullary thyroid carcinoma.
Thyrotoxicosis
Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1.
Tongue Neoplasms
Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9.
MMP-1/2 and TIMP-1/2 expression levels, and the levels of collagenous and elastic fibers correlate with disease progression in a hamster model of tongue cancer.
Prognostic significance of matrix metalloproteinase-2, -8, -9, and -13 in oral tongue cancer.
Tooth Mobility
Oxymatrine alleviates periodontitis in rats by inhibiting inflammatory factor secretion and regulating MMPs/TIMP protein expression1.
Toxocariasis
Matrix metalloproteinase-2 and matrix metalloproteinase-9 in mice with ocular toxocariasis.
Toxoplasmosis
Matrix metalloproteinase-2 and -9 lead to fibronectin degradation in astroglia infected with Toxoplasma gondii.
Up-regulation of matrix metalloproteinases-2 and -9 via an Erk1/2/NF-?B pathway in murine mast cells infected with Toxoplasma gondii.
Trauma, Nervous System
Matrix metalloproteinase-2 and -9 as promising benefactors in development, plasticity and repair of the nervous system.
Triple Negative Breast Neoplasms
Brucine suppresses breast cancer metastasis via inhibiting epithelial mesenchymal transition and matrix metalloproteinases expressions.
Docosahexaenoic acid suppresses migration of triple-negative breast cancer cell through targeting metastasis-related genes and microRNA under normoxic and hypoxic conditions.
The ras homolog gene family, member A (RhoA) pathway mediates MMP-2 and MMP-9-independent invasive behavior in a triple-negative breast cancer cell line.
Trophoblastic Neoplasms
[MMP-2/TIMP-2 expression in the trophoblasts of patients with gestational trophoblastic disease]
Tuberculosis
Activity of matrix metalloproteinase 2 and 9 isoforms in sputum samples from individuals infected with M. tuberculosis.
l-Glutamate in Middlebrook 7H9 culture medium upregulates matrix metalloproteinase-2 secretion from human astrocytoma cells.
Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNF?, NF?B, p38 and caspase 8 dependent pathways.
[Clinical significance of detecting VEGF, CD44v6, MMP-2, and MMP-9 in malignant ascites]
Tuberculosis, Meningeal
Elevated Matrix Metalloproteinase Concentrations Offer Novel Insight Into Their Role in Pediatric Tuberculous Meningitis.
Marked increase of matrix metalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculous meningoencephalitis.
Persistent increase of matrix metalloproteinases in cerebrospinal fluid of tuberculous meningitis.
Tuberous Sclerosis
TGF-beta enhances MMP-2 expression and activity through AKT in fibroblasts derived from angiofibromas in patients with tuberous sclerosis complex.
type i protein arginine methyltransferase deficiency
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma.
Uremia
Alterations in peripheral blood levels of TIMP-1, MMP-2, and MMP-9 in patients with type-2 diabetes.
Association of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 With Endothelial Dysfunction, Cardiovascular Disease Risk Factors and thrombotic events in Children With End-stage Renal Disease.
Peripheral blood level alterations of MMP-2 and MMP-9 in patients with chronic kidney disease on conservative treatment and on hemodialysis.
Plasma and Aorta Biochemistry and MMPs Activities in Female Rabbit Fed Methionine Enriched Diet and Their Offspring.
The serum levels of MMP-9, MMP-2 and vWF in patients with low doses of urokinase peritoneal dialysis decreased uremia complicated with cerebral infarction.
Ureteral Obstruction
Effect of ureteral obstruction on matrix metalloproteinase-2 in rat renal cortex.
Influence of dietary iron intake restriction on the development of hypertension in weanling prehypertensive rats.
Integrating Polydopamine Nanosphere/Aptamers Nanoplatform with DNase-I-assisted Recycling Amplification Strategy for Simultaneous Detection of MMP-9 and MMP-2 During Renal Interstitial Fibrosis.
Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy.
Matrix Metalloproteinase-2 Knockout and Heterozygote Mice Are Protected from Hydronephrosis and Kidney Fibrosis after Unilateral Ureteral Obstruction.
MMP-2 inhibition reduces renal macrophage infiltration with increased fibrosis in UUO.
Urinary Bladder Neoplasms
4-HPR impairs bladder cancer cell migration and invasion by interfering with the Wnt5a/JNK and Wnt5a/MMP-2 signaling pathways.
A novel approach to using matrix metalloproteinases for bladder cancer.
An inverse relationship between KAI1 expression, invasive ability, and MMP-2 expression and activity in bladder cancer cell lines.
Analysis of the gene expression of SPARC and its prognostic value for bladder cancer.
Association of MMP-2, RB and PAI-1 with decreased recurrence-free survival and overall survival in bladder cancer patients.
Association of single nucleotide polymorphisms in promoter of matrix metalloproteinase-2, 8 genes with bladder cancer risk in Northern India.
Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression.
Bacillus Calmette-Guérin enhances production and secretion of type IV collagenases in peripheral blood mononuclear cells.
Capsaicin attenuates cell migration via SIRT1 targeting and inhibition to enhance cortactin and ?-catenin acetylation in bladder cancer cells.
Comment to: "Detection and Molecular Staging of Bladder Cancer Using Real-Time RT-PCR for Gelatinases MMP-2, MMP-9 and TIMP-2 in Peripheral Blood"
Detection and Molecular Staging of Bladder Cancer Using Real-Time RT-PCR for Gelatinases (MMP-2, MMP-9) and TIMP-2 in Peripheral Blood.
Detection of tumor-associated antigens in culture supernatants using autoantibodies in sera from patients with bladder cancer.
Diagnostic evaluation of apoptosis inhibitory gene and tissue inhibitor matrix metalloproteinase-2 in patients with bladder cancer.
Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines.
Editorial: MMP-2 and MMP-9 in lymph-node-positive bladder cancer.
Effect of TRPV2 cation channels on the proliferation, migration and invasion of 5637 bladder cancer cells.
Effects of tumor necrosis factor-alpha and interferon-gamma on expressions of matrix metalloproteinase-2 and -9 in human bladder cancer cells.
Enhanced urinary gelatinase activities (matrix metalloproteinases 2 and 9) are associated with early-stage bladder carcinoma: a comparison with clinically used tumor markers.
Evaluation of MMP-2, MMP-9, TIMP-1, TIMP-2, NGAL and MMP-9/NGAL complex in urine and sera from patients with bladder cancer.
Excretion of matrix metalloproteinases 2 and 9 in urine is associated with a high stage and grade of bladder carcinoma.
Extra virgin olive oil phenols suppress migration and invasion of T24 human bladder cancer cells through modulation of matrix metalloproteinase-2.
Gelatin-modified gold nanoparticles for direct detection of urinary total gelatinase activity: Diagnostic value in bladder cancer.
Gelatinase isoforms in urine from bladder cancer patients.
High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer.
High VEGF-D and Low MMP-2 Serum Levels Predict Nodal-Positive Disease in Invasive Bladder Cancer.
In situ gelatinolytic activity correlates with tumor progression and prognosis in patients with bladder cancer.
Introduction of insulin-like growth factor binding protein-2 gene into human bladder cancer cells enhances their metastatic potential.
Isorhapontigenin (ISO) Inhibits Invasive Bladder Cancer Formation In Vivo and Human Bladder Cancer Invasion In Vitro by Targeting STAT1/FOXO1 Axis.
Loss of GATA3 in bladder cancer promotes cell migration and invasion.
Low Circulating Levels of ProMMP-2 Are Associated with Adverse Prognosis in Bladder Cancer.
Matrix metalloproteinase polymorphisms and bladder cancer risk.
Matrix metalloproteinase-2 immunoreactive protein as a prognostic marker in bladder cancer.
Matrix metalloproteinases (MMPs) in bladder cancer: the induction of MMP9 by epidermal growth factor and its detection in urine.
Matrix metalloproteinases and bladder cancer.
MicroRNA-106a suppresses proliferation, migration, and invasion of bladder cancer cells by modulating MAPK signaling, cell cycle regulators, and Ets-1-mediated MMP-2 expression.
MicroRNA-20b inhibits the proliferation, migration and invasion of bladder cancer EJ cells via the targeting of cell cycle regulation and Sp-1-mediated MMP-2 expression.
MiR-221-induced PUMA silencing mediates immune evasion of bladder cancer cells.
MiRNA-141 and miRNA-200b are closely related to invasive ability and considered as decision-making biomarkers for the extent of PLND during cystectomy.
MMP-2 and MMP-9 as prognostic markers for the early detection of urinary bladder cancer.
MMP-2 and MMP-9 in lymph-node-positive bladder cancer.
Noninvasive Diagnosis of Bladder Cancer by Detection of Matrix Metalloproteinases (MMP-2 and MMP-9) and Their Inhibitor (TIMP-2) in Urine.
p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.
p85? Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation.
Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and -7 and E-cadherin.
Positive Correlation between Matrix Metalloproteinases and Epithelial-to-Mesenchymal Transition and its Association with Clinical Outcome in Bladder Cancer Patients.
Profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases proteins in bladder urothelial carcinoma.
Prognostic value of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in bladder carcinoma.
Prognostic value of membrane type 1 and 2 matrix metalloproteinase expression and gelatinase A activity in bladder cancer.
Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer.
Serum tissue inhibitor of metalloproteinase-2 (TIMP-2) and matrix metalloproteinase-2 in complex with the inhibitor (MMP-2:TIMP-2) as prognostic markers in bladder cancer.
Silencing expression of the NANOG gene and changes in migration and metastasis of urinary bladder cancer cells.
Suppressions of Migration and Invasion by Cantharidin in TSGH-8301 Human Bladder Carcinoma Cells through the Inhibitions of Matrix Metalloproteinase-2/-9 Signaling.
The MMP-1, MMP-2, and MMP-9 gene polymorphisms and susceptibility to bladder cancer: a meta-analysis.
The role of matrix metalloproteinases in pathogenesis of human bladder cancer.
The value of combined use of survivin mRNA and matrix metalloproteinase 2 and 9 for bladder cancer detection in voided urine.
Tumor progression and expression of matrix metalloproteinase-2 (MMP-2) mRNA by human urinary bladder cancer cells.
Urinary gelatinase activities (matrix metalloproteinases 2 and 9) in human bladder tumors.
Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma.
[Gene expressions of type IV collagenase and tissue inhibitor of metalloproteinases (TIMP) in human bladder cancers]
[Mechanisms for effect of osthole on inhibiting the growth and invasion of bladder cancer cells].
[Prospects for molecular research in urological oncology: bladder cancer]
Urinary Incontinence
Collagen metabolism and turnover in women with stress urinary incontinence and pelvic prolapse.
Elastin metabolism in pelvic tissues: is it modulated by reproductive hormones?
Expression of matrix metalloproteinase-2 and tissue inhibitors of metalloproteinase-1 (TIMP-1, TIMP-2 and TIMP-3) in women with uterine prolapse but without urinary incontinence.
Urinary Tract Infections
Diagnostic accuracy of urine neutrophil gelatinase-associated lipocalin and urine kidney injury molecule-1 as predictors of acute pyelonephritis in young children with febrile urinary tract infection.
Early prediction of urinary tract infection with urinary neutrophil gelatinase associated lipocalin.
Increased urinary neutrophil gelatinase associated lipocalin in urinary tract infections and leukocyturia.
Increased urinary neutrophil gelatinase associated lipocalin levels in a rat model of upper urinary tract infection.
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Urinary Neutrophil Gelatinase Associated Lipocalin - A Sensitive Marker for Urinary Tract Infection in Children.
[Virulence genes and bacteriocins in Enterococcus faecalis strains isolated from different clinical samples in Maule Region, Chile].
Uterine Cervical Neoplasms
A coumarin-based fluorescence resonance energy transfer probe targeting matrix metalloproteinase-2 for the detection of cervical cancer.
A model for co-expression pattern analysis of genes implicated in angiogenesis and tumour cell invasion in cervical cancer.
A novel role of metalloproteinase in cancer-mediated immunosuppression.
A Study of Matrix Metalloproteinase-2 and Interleukin-18 in Preinvasive and Invasive Lesions of Cancer Cervix.
AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis.
Anti-Cancer Activity of As4O6 and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer.
Anti-tumor activity of staurosporine in the tumor microenvironment of cervical cancer: An in vitro study.
Bisdemethoxycurcumin Suppresses Migration and Invasion of Human Cervical Cancer HeLa Cells via Inhibition of NF-?B, MMP-2 and -9 Pathways.
Cell membrane-associated MT1-MMP-dependent activation of pro-MMP-2 in A375 melanoma cells.
Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form.
Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review.
Clinical significance of matrix metalloproteinase-2 in cancer of uterine cervix: a semiquantitative study of immunoreactivities using tissue array.
Combined delivery of salinomycin and docetaxel by dual-targeting gelatinase nanoparticles effectively inhibits cervical cancer cells and cancer stem cells.
Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma.
Culture of human cervical cancer cells, SiHa, in the presence of fibronectin activates MMP-2.
Diagnostic Power of Cytokine M-CSF, Metalloproteinase 2 (MMP-2) and Tissue Inhibitor-2 (TIMP-2) in Cervical Cancer Patients Based on ROC Analysis.
E6/E7 oncoproteins of high risk HPV-16 upregulate MT1-MMP, MMP-2 and MMP-9 and promote the migration of cervical cancer cells.
Effect of human seminal fluid on production of messenger ribonucleic acid for metalloproteinase 2 and metalloproteinase 9 in cervical epithelial carcinoma cells.
Effects of Galectin-1 on Biological Behavior in Cervical Cancer.
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma.
Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.
Expression of MAPK1 in cervical cancer and effect of MAPK1 gene silencing on epithelial-mesenchymal transition, invasion and metastasis.
Expression of matrix metalloproteinase-2 and 9 in cervical intraepithelial neoplasia and cervical carcinoma among different age groups of premenopausal and postmenopausal women.
Extracellular matrix metalloproteinase inducer (EMMPRIN) remodels the extracellular matrix through enhancing matrix metalloproteinases (MMPs) and inhibiting tissue inhibitors of MMPs expression in HPV-positive cervical cancer cells.
FOXM1 promotes tumor cell invasion and correlates with poor prognosis in early-stage cervical cancer.
Genetic polymorphisms in MMP 2, 3, 7, and 9 genes and the susceptibility and clinical outcome of cervical cancer in a Chinese Han population.
HPV16 Oncoproteins Promote Cervical Cancer Invasiveness by Upregulating Specific Matrix Metalloproteinases.
Human nonmetastatic clone 23 type 1 gene suppresses migration of cervical cancer cells and enhances the migration inhibition of fungal immunomodulatory protein from Ganoderma tsugae.
Immunohistochemical detection of matrix metalloproteinases (MMP) 1 and 2, and tissue inhibitor of metalloproteinase 2 (TIMP 2) in stage IB cervical cancer.
In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors.
Matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor (TIMP-2) are prognostic factors in cervical cancer, related to invasive disease but not to high-risk human papillomavirus (HPV) or virus persistence after treatment of CIN.
Matrix metalloproteinases-2 and -9 in cervical cancer: different roles in tumor progression.
Membrane-associated MMP-2 in human cervical cancer.
MicroRNA-106a promotes cell migration and invasion by targeting tissue inhibitor of matrix metalloproteinase 2 in cervical cancer.
MicroRNA-99b suppresses human cervical cancer cell activity by inhibiting the PI3K/AKT/mTOR signaling pathway.
MMP-2 and MMP-9 gene polymorphisms associated with cervical cancer risk.
No Association of Matrix Metalloproteinase [MMP]-2 (-735C > T) and Tissue Inhibitor of Metalloproteinase [TIMP]-2 (-418G > C) Gene Polymorphisms with Cervical Cancer Susceptibility.
Overexpression of myeloid zinc finger 1 suppresses matrix metalloproteinase-2 expression and reduces invasiveness of SiHa human cervical cancer cells.
Polymorphism in the Matrix Metalloproteinase-2 Gene Promoter is Associated with Cervical Neoplasm Risk in Mexican Women.
Praeruptorin A Inhibits Human Cervical Cancer Cell Growth and Invasion by Suppressing MMP-2 Expression and ERK1/2 Signaling.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells.
Role of serum VEGFA, TIMP2, MMP2 and MMP9 in monitoring response to adjuvant radiochemotherapy in patients with primary cervical cancer--results of a companion protocol of the randomized NOGGO-AGO phase III clinical trial.
Semi-quantitative expression of tissue inhibitor of matrix metalloproteinase-2 in cancer of uterine cervix.
Stromal cells play a role in cervical cancer progression mediated by MMP-2 protein.
TCEB3 is Regulated by Circ-0000212/miR-140-3p Axis to Promote the Progression of Cervical Cancer.
The aqueous extract of Ficus religiosa induces cell cycle arrest in human cervical cancer cell lines SiHa (HPV-16 Positive) and apoptosis in HeLa (HPV-18 positive).
The association of semaphorin 5A with lymph node metastasis and adverse prognosis in cervical cancer.
The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity.
The protective role of the -1306C>T functional polymorphism in matrix metalloproteinase-2 gene is associated with cervical cancer: implication of human papillomavirus infection.
Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
[Baicalein induces HeLa cell growth inhibition by down-regulation of matrix metalloproteinases and activating extracellular signal-regulated kinase].
[FABP5 promotes cell growth, invasion and metastasis in cervical cancer].
[The expression of matrix metalloproteinase-2 and -9 in cervical cancer and a study of their relationship]
[The Role and Mechanism of CXCR4 and Its Ligand SDF-1 in the Development of Cervical Cancer Metastasis.]
Uterine Neoplasms
Uterine cervical carcinoma: Role of matrix metalloproteinases (Review).
[Prognostic value of serum MMP-2 level in uterine cancer affected women]
Uterine Prolapse
Expression of matrix metalloproteinase-2 and tissue inhibitors of metalloproteinase-1 (TIMP-1, TIMP-2 and TIMP-3) in women with uterine prolapse but without urinary incontinence.
Gene expression and immunoreactivity of elastolytic enzymes in the uterosacral ligaments from women with uterine prolapse.
High isoprostane level in cardinal ligament-derived fibroblasts and urine sample of women with uterine prolapse.
Uveitis
Chemokines and gelatinases in the aqueous humor of patients with active uveitis.
Correlation of metalloproteinase-2 and -9 with proinflammatory cytokines interleukin-1b, interleukin-12 and the interleukin-1 receptor antagonist in patients with chronic uveitis.
Inhibition of MMP-dependent chemotaxis and amelioration of experimental autoimmune uveitis with a selective metalloproteinase-2 and -9 inhibitor.
Neutrophil accumulation correlates with type IV collagenase/gelatinase activity in endotoxin induced uveitis.
v-cath endopeptidase deficiency
Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.
Vaccinia
Expression of human recombinant 72 kDa gelatinase and tissue inhibitor of metalloproteinase-2 (TIMP-2): characterization of complex and free enzyme.
Vaginosis, Bacterial
Relationship between metalloproteinase-2 and -9 levels in plasma and vaginal secretion with preterm birth.
Varicocele
Impact of micronised purified flavonoid fraction on increased malondialdehyde and decreased metalloproteinase-2 and metalloproteinase-9 levels in varicocele: outcome of an experimentally induced varicocele.
Varicose Ulcer
Matrix metalloproteinase (MMP)-1 and MMP-2, but not COX-2 serve as additional predictors for chronic venous ulcer healing.
Matrix Metalloproteinases in Vascular Disease - A Potential Therapeutic Target?
The Impact of Differential Expression of Extracellular Matrix Metalloproteinase Inducer, Matrix Metalloproteinase-2, Tissue Inhibitor of Matrix Metalloproteinase-2 and PDGF-AA on the Chronicity of Venous Leg Ulcers.
The Impact of Valvular Oxidative Stress on the Development of Venous Stasis Ulcer Valvular Oxidative Stress and Venous Ulcers.
Varicose Veins
Comparison of extracellular matrix in skin and saphenous veins from patients with varicose veins: does the skin reflect venous matrix changes?
Effect of a Peptide Construct on Differentiated Macrophage MMP-2 and MMP-9 Levels of Varicose Patients.
Expression levels of elastin and related genes in human varicose veins.
Expression of matrix metalloproteinase-2 and -13 and tissue inhibitor of metalloproteinase-4 in varicose veins.
In vitro differences between smooth muscle cells derived from varicose veins and normal veins.
Increased TIMP/MMP ratio in varicose veins: a possible explanation for extracellular matrix accumulation.
Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation.
Matrix metalloproteinases in the vein wall.
Metalloproteinase expression in venous aneurysms.
MMP-2 Induced Vein Relaxation via Inhibition of [Ca(2+)](e)-Dependent Mechanisms of Venous Smooth Muscle Contraction. Role of RGD Peptides.
Morphologic characteristics of varicose veins: possible role of metalloproteinases.
Pathogenesis of primary varicose veins.
Role of mechanosignaling on pathology of varicose vein.
Tissue inhibitor of metalloproteinase-1 is increased in the saphenofemoral junction of patients with varices in the leg.
Vascular Calcification
Gelatinases promote calcification of vascular smooth muscle cells by up-regulating bone morphogenetic protein-2.
Involvement of matrix metalloproteinase-2 in the development of medial layer vascular calcification in uremic rats.
The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2.
The matrix metalloproteinases 2 and 9 initiate uraemic vascular calcifications.
Vascular smooth muscle cell differentiation to an osteogenic phenotype involves matrix metalloproteinase-2 modulation by homocysteine.
Vitamin D receptor activators inhibit vascular smooth muscle cell mineralization induced by phosphate and TNF-?
Vascular Diseases
Aging is associated with increased matrix metalloproteinase-2 activity in the human aorta.
Angiotensin II Induces the Vascular Expression of VEGF and MMP-2 in vivo: Preventive Effect of Red Wine Polyphenols.
Effect of erythromycin on homocysteine-induced extracellular matrix metalloproteinase-2 production in cultured rat vascular smooth muscle cells.
Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and -9, and their inhibitors, tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2.
Gelatinase-mediated migration and invasion of cancer cells.
In vitro inhibition of human MMP-2 collagenolytic and gelatinolytic activity by neutralizing monoclonal antibodies.
Inhibition of lysyl oxidase stimulates TGF-? signaling and metalloproteinases-2 and -9 expression and contributes to the disruption of ascending aorta in rats: protection by propylthiouracil.
Involvement of Matrix Metalloproteinase 9 in Vertebral Arterial Dissection With Posterior Circulation Ischemic Stroke.
Optical Interference-Free Surface-Enhanced Raman Scattering CO-Nanotags for Logical Multiplex Detection of Vascular Disease-Related Biomarkers.
Vascular Malformations
Angiogenesis in autosomal-dominant polycystic kidney disease.
Cellular markers that distinguish the phases of hemangioma during infancy and childhood.
Vascular System Injuries
Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP.
Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts.
Antagonism of platelet-derived growth factor by perivascular gene transfer attenuates adventitial cell migration after vascular injury: new tricks for old dogs?
Flow regulation of 72-kD collagenase IV (MMP-2) after experimental arterial injury.
Function of the plasminogen/plasmin and matrix metalloproteinase systems after vascular injury in mice with targeted inactivation of fibrinolytic system genes.
Hydrogen sulfide protects against vascular remodeling from endothelial damage.
Increased expression of membrane-type matrix metalloproteinase and preferential localization of matrix metalloproteinase-2 to the neointima of balloon-injured rat carotid arteries.
Matrix metalloproteinase-2 knockout prevents angiotensin II-induced vascular injury.
Montelukast inhibits matrix metalloproteinases expression in atherosclerotic rabbits.
OS 15-02 MATRIX METALLOPROTEINASE 2 KNOCKOUT PROTECTS FROM ANGIOTENSIN II-INDUCED VASCULAR INJURY IN PART VIA INHIBITION OF EGFR AND ERK1/2 ACTIVATION.
Platelets release active matrix metalloproteinase-2 in vivo in humans at a site of vascular injury: lack of inhibition by aspirin.
Role of the fibrinolytic and matrix metalloproteinase systems in arterial neointima formation after vascular injury.
Stromelysin-1 (MMP-3)-independent gelatinase expression and activation in mice.
Thrombin promotes activation of matrix metalloproteinase-2 produced by cultured vascular smooth muscle cells.
Vasculitis
Early Kidney Injury in Immunoglobulin A Vasculitis: Role of Renal Biomarkers.
Modulation of MMP-2 and MMP-9 in Churg-Strauss syndrome respiratory mucosa: potential monitoring parameters.
Neutrophil gelatinase levels in plasma and synovial fluid of patients with rheumatic diseases.
Serum MMP-2 and MMP-9 in patients with Behçet's disease: Do their higher levels correlate to vasculo-Behçet's disease associated with aneurysm formation?
Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells.
Urinary matrix metalloproteinases reflect renal damage in anti-neutrophil cytoplasm autoantibody-associated vasculitis.
Venereal Tumors, Veterinary
Immunocharacterization of matrix metalloproteinase-2 and matrix metalloproteinase-9 in canine transmissible venereal tumors.
Venous Insufficiency
Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration.
Sulodexide Improves Contraction and Decreases Matrix Metalloproteinase-2 and -9 in Veins Under Prolonged Stretch.
Venous Thrombosis
Differential transcriptional activation of matrix metalloproteinase-2 and membrane type-1 matrix metalloproteinase by experimental deep venous thrombosis and thrombin.
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Immunohistochemical detection of MMP-2 and MMP-9 in a stasis-induced deep vein thrombosis model and its application to thrombus age estimation.
Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice.
Resistin Promotes Thrombosis in Rats with Deep Vein Thrombosis via Up-Regulating MMP-2, MMP-9, and PAI-1.
Ventricular Dysfunction
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction.
Soluble TNF receptors prevent apoptosis in infiltrating cells and promote ventricular rupture and remodeling after myocardial infarction.
Ventricular Dysfunction, Left
Ethanol extract from Epimedium brevicornum attenuates left ventricular dysfunction and cardiac remodeling through down-regulating matrix metalloproteinase-2 and -9 activity and myocardial apoptosis in rats with congestive heart failure.
Euterpe oleracea Mart. (Açai) Supplementation Attenuates Acute Doxorubicin-Induced Cardiotoxicity in Rats.
Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure.
Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction.
Relationships between plasma levels of matrix metalloproteinases and neurohormonal profile in patients with heart failure.
Ventricular Fibrillation
Dynamic alterations of connexin43, matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 during ventricular fibrillation in canine.
Viremia
Silybin-vitamin E-phospholipids complex reduces liver fibrosis in patients with chronic hepatitis C treated with pegylated interferon ? and ribavirin.
Virus Diseases
Acute exacerbations of COPD are associated with significant activation of matrix metalloproteinase 9 irrespectively of airway obstruction, emphysema and infection.
In vitro infection of macrophages by HIV: correlation with cellular activation, synthesis of tumour necrosis factor alpha and proteolytic activity.
Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma.
Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.
Influenza A virus infection modulates the expression of type IV collagenase in epithelial cells.
Regulation of Matrix Metalloproteinases-2 and -9 Gene Expression in Cultured Human Fetal Membrane Cells by Influenza Virus Infection.
Severity of Plasma Leakage Is Associated With High Levels of Interferon ?-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
Vitamin A Deficiency
Neutrophil cathepsin G is specifically decreased under vitamin A deficiency.
Vitamin D Deficiency
Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease.
Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model.
Vitiligo
Altered levels of Ets-1 transcription factor and metalloproteinases in melanocytes from vitiligo patients.
In vitro migration of melanoblasts requires matrix metalloproteinase-2: implications to vitiligo therapy by photochemotherapy.
The clinical and pathological effectiveness of microneedling and topical 5-fluorouracil in vitiligo treatment: An association with matrix metalloproteinase 2 immunohistochemical expression.
Vitreoretinopathy, Proliferative
Predominance of MMP-1 and MMP-2 in epiretinal and subretinal membranes of proliferative vitreoretinopathy.
Vitreous Detachment
Intravitreal plasmin injection activates endogenous matrix metalloproteinase-2 in rabbit and human vitreous.
Vitreous Hemorrhage
The activated form of gelatinase B/matrix metalloproteinase-9 is associated with diabetic vitreous hemorrhage.
Vulvar Neoplasms
A comparative study of MMP-2 in vulvar neoplasms.
Whooping Cough
Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity.
Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways.
Role of MMP-2 in PKCdelta-mediated inhibition of Na+ dependent Ca2+ uptake in microsomes of pulmonary smooth muscle: involvement of a pertussis toxin sensitive protein.
Wilms Tumor
Renal Fibrosis mRNA Classifier: Validation in Experimental Lithium-Induced Interstitial Fibrosis in the Rat Kidney.
Suppression of tumorigenicity of rhabdoid tumor derived G401 cells by the multivalent HB-19 pseudopeptide that targets surface nucleolin.
Wiskott-Aldrich Syndrome
Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways.
Wound Infection
Matrix metalloproteinases in rectal mucosa, tumour and plasma: response after preoperative irradiation.
Methamphetamine Alters the Antimicrobial Efficacy of Phagocytic Cells during Methicillin-Resistant Staphylococcus aureus Skin Infection.