Reference on EC 3.4.24.21 - astacin
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dumermuth, E.; Sterchi, E.E.; Jiang, W.; Wolz, R.L.; Bond, J.S.; Flannery, A.V.; Beynon, R.J.
The astacin family of metalloendopeptidases
J. Biol. Chem.
266
21381-21385
1991
Astacus astacus
Wolz, R.L.
A kinetic comparison of the homologous proteases astacin and meprin A
Arch. Biochem. Biophys.
310
144-151
1994
Astacus astacus
Krauhs, E.; Dörsam, H.; Little, M.; Zwilling, R.; Ponstingl, H.
A protease from Astacus fluviatilis as an aid in protein sequencing
Anal. Biochem.
119
153-157
1982
Astacus astacus
Titani, K.; Torff, H.J.; Hormel, S.; Kumar, S.; Walsh, K.A.; Rödl, J.; Neurath, H.; Zwilling, R.
Amino acid sequence of a unique protease from the crayfish Astacus fluviatilis
Biochemistry
26
222-226
1987
Astacus astacus
Stöcker, W.; Wolz, R.L.; Zwilling, R.; Strydom, D.J.; Auld, D.S.
Astacus protease, a zinc metalloenzyme
Biochemistry
27
5026-5032
1988
Astacus astacus
-
Stöcker, W.; Ng, M.; Auld, D.S.
Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease
Biochemistry
29
10418-10425
1990
Astacus astacus
Bode, W.; Gomis-Ruth, F.X.; Huber, R.; Zwilling, R.; Stöcker, W.
Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases
Nature
358
164-167
1992
Astacus astacus
Gomis-Ruth, F.X.; Stöcker, W.; Huber, R.; Zwilling, R.; Bode, W.
Refined 1.8 A X-ray crystal structure of astacin, a zinc-endopeptidase from the crayfish Astacus astacus L. Structure determination, refinement, molecular structure and comparison with thermolysin
J. Mol. Biol.
229
945-968
1993
Astacus astacus
Stöcker, W.; Gomis-Ruth, F.X.; Bode, W.; Zwilling, R.
Implications of the three-dimensional structure of astacin for the structure and function of the astacin family of zinc-endopeptidases
Eur. J. Biochem.
214
215-231
1993
Astacus astacus
Gomis-Ruth, F.X.; Grams, F.; Yiallouros, I.; Nar, H.; Kusthardt, U.; Zwilling, R.; Bode, W.; Stöcker, W.
Crystal structures, spectroscopic features, and catalytic properties of cobalt(II), copper(II), nickel(II), and mercury(II) derivatives of the zinc endopeptidase astacin. A correlation of structure and proteolytic activity
J. Biol. Chem.
269
17111-17117
1994
Astacus astacus
Zwilling, R.; Neurath, H.
Invertebrate proteases
Methods Enzymol.
80C
633-664
1981
Astacus astacus, Carcinus maenas, Astacus leptodactylus
-
Bode, W.; Gomis-Ruth, F.X.; Stöckler, W.
Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the metzincins
FEBS Lett.
331
134-140
1993
Astacus astacus
Yiallouros, I.; Vassiliou, S.; Yiotakis, A.; Zwilling, R.; Stoecker, W.; Dive, V.
Phosphinic peptides, the first potent inhibitors of astacin, behave as extremely slow-binding inhibitors
Biochem. J.
331
375-379
1998
Astacus astacus
Reyda, S.; Jacob, E.; Zwilling, R.; Stoecker, W.
cDNA cloning, bacterial expression, in vitro renaturation and affinity purification of the zinc endopeptidase astacin
Biochem. J.
344
851-857
1999
Astacus astacus
Hung, C.H.; Huang, H.R.; Huang, C.J.; Huang, F.L.; Chang, G.D.
Purification and cloning of carp nephrosin, a secreted zinc endopeptidase of the astacin family
J. Biol. Chem.
272
13772-13778
1997
Cyprinus carpio (O42326), Cyprinus carpio
Tsai, P.L.; Chen, C.H.; Huang, C.J.; Chou, C.M.; Chang, G.D.
Purification and cloning of an endogenous protein inhibitor of carp nephrosin, an astacin metalloproteinase
J. Biol. Chem.
279
11146-11155
2004
Cyprinus carpio
Foradori, M.J.; Tillinghast, E.K.; Smith, J.S.; Townley, M.A.; Mooney, R.E.
Astacin family metallopeptidases and serine peptidase inhibitors in spider digestive fluid
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
143
257-268
2006
Argiope aurantia (P84748), Argiope aurantia
Semenova, S.A.; Rudenskaya, G.N.; Rebrikov, D.V.; Isaev, V.A.
cDNA cloning, purification and properties of Paralithodes camtschatica metalloprotease
Protein Pept. Lett.
13
571-575
2006
Paralithodes camtschaticus
Becker-Pauly, C.; Bruns, B.C.; Damm, O.; Schuette, A.; Hammouti, K.; Burmester, T.; Stoecker, W.
News from an ancient world: two novel astacin metalloproteases from the horseshoe crab
J. Mol. Biol.
385
236-248
2009
Limulus polyphemus
Guevara, T.; Yiallouros, I.; Kappelhoff, R.; Bissdorf, S.; Stoecker, W.; Gomis-Rueth, F.X.
Proenzyme structure and activation of astacin metallopeptidase
J. Biol. Chem.
285
13958-13965
2010
Astacus astacus (Q9U918), Astacus astacus
Stepek, G.; McCormack, G.; Page, A.
Collagen processing and cuticle formation is catalysed by the astacin metalloprotease DPY-31 in free-living and parasitic nematodes
Int. J. Parasitol.
40
533-542
2010
Brugia malayi, Caenorhabditis elegans, Haemonchus contortus
Tsuchiya, S.; Simmer, J.P.; Hu, J.C.; Richardson, A.S.; Yamakoshi, F.; Yamakoshi, Y.
Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp)
J. Bone Miner. Res.
26
220-228
2011
Sus scrofa
Jing, Y.; Toubarro, D.; Hao, Y.; Simoes, N.
Cloning, characterisation and heterologous expression of an astacin metalloprotease, Sc-AST, from the entomoparasitic nematode Steinernema carpocapsae
Mol. Biochem. Parasitol.
174
101-108
2010
Steinernema carpocapsae (D2KBH9), Steinernema carpocapsae
Stepek, G.; McCormack, G.; Birnie, A.J.; Page, A.P.
The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes
Parasitology
138
237-248
2011
Brugia malayi, Caenorhabditis elegans
Gomis-Rueth, F.X.; Trillo-Muyo, S.; Stoecker, W.
Functional and structural insights into astacin metallopeptidases
Biol. Chem.
393
1027-1041
2012
Caenorhabditis elegans, Cyprinus carpio, Onchocerca volvulus, Trichinella spiralis, Astacus astacus (P07584)
Baska, P.; Wisniewski, M.; Krzyzowska, M.; Dlugosz, E.; Zygner, W.; Gorski, P.; Wedrychowicz, H.
Molecular cloning and characterisation of in vitro immune response against astacin-like metalloprotease Ace-MTP-2 from Ancylostoma ceylanicum
Exp. Parasitol.
133
472-482
2013
Ancylostoma ceylanicum (Q0Z889), Ancylostoma ceylanicum
Hong, C.S.; Saint-Jeannet, J.P.
Xhe2 is a member of the astacin family of metalloproteases that promotes Xenopus hatching
Genesis
52
946-951
2014
Xenopus laevis (Q63ZG3)
Stepek, G.; McCormack, G.; Winter, A.D.; Page, A.P.
A highly conserved, inhibitable astacin metalloprotease from Teladorsagia circumcincta is required for cuticle formation and nematode development
Int. J. Parasitol.
45
345-355
2015
Teladorsagia circumcincta (A0A0C5PRQ1), Teladorsagia circumcincta, Haemonchus contortus (D5FM33), Haemonchus contortus, Caenorhabditis elegans (P98060), Caenorhabditis elegans, Haemonchus contortus ISE (D5FM33), Caenorhabditis elegans N2 (P98060), Teladorsagia circumcincta MTci5 (A0A0C5PRQ1)
Liang, Y.; Bai, D.; Yang, G.; Wei, D.; Guo, M.; Yan, S.; Wu, X.; Ning, B.
Effect of astacin on growth and color formation of juvenile red-white ornamental carp (Cyprinus carpio var. koi L)
Isr. J. Aquacult.
64
0000
2012
Cyprinus carpio
-
Chen, S.L.; Li, Z.S.; Fang, W.H.
Theoretical investigation of astacin proteolysis
J. Inorg. Biochem.
111
70-79
2012
Astacus astacus (P07584)
Morgon, A.; Belisario-Ferrari, M.; Trevisan-Silva, D.; Meissner, G.; Vuitika, L.; Marin, B.; Tashima, A.; Gremski, L.; Gremski, W.; Senff-Ribeiro, A.; Veiga, S.; Chaim, O.
Expression and immunological cross-reactivity of LALP3, a novel astacin-like metalloprotease from brown spider (Loxosceles intermedia) venom
Biochimie
128-129
8-19
2016
Loxosceles intermedia (C9D7R3), Loxosceles intermedia
Schneppenheim, J.; Scharfenberg, F.; Lucius, R.; Becker-Pauly, C.; Arnold, P.
Meprin beta and BMP-1 are differentially regulated by CaCl2
Cell Calcium
65
8-13
2017
Homo sapiens (P13497), Homo sapiens
Sarkar, I.
To compare the active sites of a series of astacin family proteases by multiple sequence alignment and homology modelling methods
Comput. Adv. Commun. Circ. Syst.: ICCACCS 2014
335
145-150
2015
Homo sapiens (P13497)
-
Chaudhuri, A.; Chakraborty, S.
Structure-activity relationship of astacin metalloproteases A comparative study using EDTA
Curr. Enzyme Inhib.
14
131-140
2018
Coturnix japonica (P42662), Homo sapiens (Q6HA08)
-
Isolani, M.E.; Batistoni, R.; Ippolito, C.; Bianucci, A.M.; Marracci, S.; Rossi, L.
Astacin gene family of metalloproteinases in planarians structural organization and tissue distribution
Gene Expr. Patterns
28
77-86
2018
Schmidtea mediterranea, Schmidtea mediterranea (A0A060Q6V2), Schmidtea mediterranea (A0A060Q6Y6), Schmidtea mediterranea (A0A060Q714), Schmidtea mediterranea (A0A060Q715), Schmidtea mediterranea (A0A060Q750), Schmidtea mediterranea (A0A060Q785), Schmidtea mediterranea (A0A060Q786), Schmidtea mediterranea (I1ZIC3)
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