Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Acne Vulgaris
Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis.
Acute Kidney Injury
Clinical risk factors and inflammatory biomarkers of post-traumatic acute kidney injury in combat patients.
Adenocarcinoma
Medroxyprogesterone Reverses Tolerable Dose Metformin-Induced Inhibition of Invasion via Matrix Metallopeptidase-9 and Transforming Growth Factor-?1 in KLE Endometrial Cancer Cells.
Adenocarcinoma of Lung
Filamin B extensively regulates transcription and alternative splicing, and is associated with apoptosis in HeLa cells.
Adenocarcinoma of Lung
Therapeutic effect of Resveratrol in the treatment of osteoarthritis via the MALAT1/miR-9/NF-?B signaling pathway.
Adenoma
Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-ras oncogene.
Adenoma
Role of gene expression profiling in defining indeterminate thyroid nodules in addition to BRAF analysis.
Adenomatous Polyposis Coli
Chromosomal and methylation alterations in sporadic and familial adenomatous polyposis-related duodenal carcinomas.
Adenomatous Polyposis Coli
Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas.
Alzheimer Disease
Elucidation of interactions of Alzheimer amyloid beta peptides (Abeta40 and Abeta42) with insulin degrading enzyme: a molecular dynamics study.
Alzheimer Disease
Examination of the role of endopeptidase 3.4.24.15 in A beta secretion by human transfected cells.
Alzheimer Disease
Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease.
Alzheimer Disease
Human endopeptidase 24.15 (THOP1) is localized on chromosome 19p13.3 and is excluded from the linkage region for late-onset Alzheimer disease.
Alzheimer Disease
Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation.
Alzheimer Disease
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Alzheimer Disease
Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain.
Alzheimer Disease
Neprilysin impedes islet amyloid formation by inhibition of fibril formation rather than peptide degradation.
Alzheimer Disease
Octyl Gallate Markedly Promotes Anti-Amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation.
Alzheimer Disease
Platelet a disintegrin and metallopeptidase 10 expression correlates with clock drawing test scores in Alzheimer's disease.
Alzheimer Disease
Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.
Alzheimer Disease
The neuroprotector kynurenic acid increases neuronal cell survival through neprilysin induction.
Angioedema
Angiotensin-converting enzyme inhibitor-associated angioedema is characterized by a slower degradation of des-arginine(9)-bradykinin.
Angioedemas, Hereditary
Metallopeptidase activities in hereditary angioedema: effect of androgen prophylaxis on plasma aminopeptidase P.
Anthrax
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity.
Anthrax
Identification of a novel zinc metalloprotease through a global analysis of Clostridium difficile extracellular proteins.
Anthrax
The cytotoxic activity of Bacillus anthracis lethal factor is inhibited by leukotriene A4 hydrolase and metallopeptidase inhibitors.
Anthrax
The structure of Mlc titration factor A (MtfA/YeeI) reveals a prototypical zinc metallopeptidase related to anthrax lethal factor.
Aortic Aneurysm
Activities of proteases in parietal thrombus of aortic aneurysm.
Aortic Aneurysm, Thoracic
Association of a matrix metallopeptidase 1 gene polymorphism with long-term outcome of thoracic aortic aneurysm.
Arthritis
HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.
Arthritis, Experimental
HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.
Asthma
ADAM metallopeptidase domain 33 (ADAM33): identification and role in airways disease.
Asthma
Effect of montelukast on markers of airway remodeling in children with asthma.
Atherosclerosis
Transcriptomic profiling of platelet senescence and platelet extracellular vesicles.
Atrial Fibrillation
Role of matrix metalloproteinase?7 and apoptosis?associated gene expression levels in the pathogenesis of atrial fibrosis in a Beagle dog model.
Bacterial Infections
Structure of the catalytic domain of the Tannerella forsythia matrix metallopeptidase karilysin in complex with a tetrapeptidic inhibitor.
Bone Cysts
The role of lysosomes in the pathogenesis of unicameral bone cysts.
Bone Neoplasms
Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer.
Bone Resorption
2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice.
Bone Resorption
Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-?B Pathway.
Breast Neoplasms
Expression of VEGF, COX-2 and MMP-9 in breast cancer and their relationship with ultrasound findings.
Breast Neoplasms
Hydroxytyrosol Supplementation Modifies Plasma Levels of Tissue Inhibitor of Metallopeptidase 1 in Women with Breast Cancer.
Breast Neoplasms
Identification of the effects of acid-resistant Lactobacillus casei metallopeptidase gene under colon-specific promoter on the colorectal and breast cancer cell lines.
Breast Neoplasms
Matrix Metallopeptidase 3 Polymorphisms: Emerging genetic Markers in Human Breast Cancer Metastasis.
Breast Neoplasms
Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer.
Candidiasis
Improved immunodiagnosis of human candidiasis by an enzyme-linked immunosorbent assay using a Candida albicans 52-kilodalton metallopeptidase.
Carcinogenesis
ADAMTS8 Inhibits Progression of Esophageal Squamous Cell Carcinoma.
Carcinogenesis
Fra-1 regulation of Matrix Metallopeptidase-1 (MMP-1) in metastatic variants of MDA-MB-231 breast cancer cells.
Carcinogenesis
High LINC01605 expression predicts poor prognosis and promotes tumor progression via up-regulation of MMP9 in bladder cancer.
Carcinogenesis
Molecular characterization and expression of a disintegrin and metalloproteinase with thrombospondin motifs 8 in chicken.
Carcinogenesis
Transcript response of soft coral (Scleronephthya gracillimum) on exposure to polycyclic aromatic hydrocarbons.
Carcinoma
Activated macrophages are crucial during acute PM2.5 exposure-induced angiogenesis in lung cancer.
Carcinoma
CD10 Expression in Epithelial and Stromal Cells of Non-small Cell Lung Carcinoma (NSCLC): A Clinic and Pathologic Correlation.
Carcinoma
Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10.
Carcinoma
Differential expression of degradome components in cutaneous squamous cell carcinomas.
Carcinoma
Distinctive gene expression profiles by cDNA microarrays in endometrioid and serous carcinomas of the endometrium.
Carcinoma
Ets-1/Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells.
Carcinoma
Fra-1 regulation of Matrix Metallopeptidase-1 (MMP-1) in metastatic variants of MDA-MB-231 breast cancer cells.
Carcinoma
MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion.
Carcinoma
Oncocytoma-like renal tumor with transformation toward high-grade oncocytic carcinoma: a unique case with morphologic, immunohistochemical, and genomic characterization.
Carcinoma
Overexpression of golgi membrane protein 1 promotes non-small-cell carcinoma aggressiveness by regulating the matrix metallopeptidase 13.
Carcinoma
Regulation of aminopeptidase A expression in cervical carcinoma: role of tumor-stromal interaction and vascular endothelial growth factor.
Carcinoma
Silencing of nuclear factor kappa b 1 gene expression inhibits colony formation, cell migration and invasion via the downregulation of interleukin 1 beta and matrix metallopeptidase 9 in renal cell carcinoma.
Carcinoma
The role of metalloendopeptidases in oropharyngeal carcinomas assessed by tissue microarray.
Carcinoma
The Sp1-mediaded allelic regulation of MMP13 expression by an ESCC susceptibility SNP rs2252070.
Carcinoma, Hepatocellular
Expression Analysis of THOP1 in Background Liver, a Prognostic Predictive Factor in Hepatocellular Carcinoma, Extracted by Multiarray Analysis.
Carcinoma, Hepatocellular
Role of Matrix Metallopeptidase 12 in the Development of Hepatocellular Carcinoma.
Carcinoma, Lewis Lung
Activated macrophages are crucial during acute PM2.5 exposure-induced angiogenesis in lung cancer.
Carcinoma, Non-Small-Cell Lung
Expression of THOP1 and its relationship to prognosis in non-small cell lung cancer.
Carcinoma, Ovarian Epithelial
Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells.
Carcinoma, Renal Cell
Silencing of nuclear factor kappa b 1 gene expression inhibits colony formation, cell migration and invasion via the downregulation of interleukin 1 beta and matrix metallopeptidase 9 in renal cell carcinoma.
Carcinoma, Squamous Cell
Differential expression of degradome components in cutaneous squamous cell carcinomas.
Carcinoma, Squamous Cell
MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion.
Carcinoma, Squamous Cell
Regulation of aminopeptidase A expression in cervical carcinoma: role of tumor-stromal interaction and vascular endothelial growth factor.
Carcinoma, Squamous Cell
The role of metalloendopeptidases in oropharyngeal carcinomas assessed by tissue microarray.
Cardiomegaly
Decreased cardiac mitochondrial tetrahydrobiopterin in a rat model of pressure overload.
Cardiovascular Diseases
Inhibition of zinc metallopeptidases in cardiovascular disease--from unity to trinity, or duality?
Cervical Intraepithelial Neoplasia
Regulation of aminopeptidase A expression in cervical carcinoma: role of tumor-stromal interaction and vascular endothelial growth factor.
Chromoblastomycosis
1,10-Phenanthroline Inhibits the Metallopeptidase Secreted by Phialophora verrucosa and Modulates its Growth, Morphology and Differentiation.
Coinfection
Transcriptional and Pathological Host Responses to Coinfection with Virulent or Attenuated Mycoplasma gallisepticum and Low-Pathogenic Avian Influenza A Virus in Chickens.
Colitis, Ulcerative
HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.
Colonic Neoplasms
Identification of the effects of acid-resistant Lactobacillus casei metallopeptidase gene under colon-specific promoter on the colorectal and breast cancer cell lines.
Colorectal Neoplasms
An immunosensor for the determination of carcinoembryonic antigen by Surface Plasmon Resonance imaging.
Colorectal Neoplasms
Circular RNA hsa_circ_0053277 promotes the development of colorectal cancer by upregulating matrix metallopeptidase 14 via miR-2467-3p sequestration.
Colorectal Neoplasms
Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer.
Colorectal Neoplasms
Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer.
Colorectal Neoplasms
Profile of Expression of Genes Encoding Matrix Metallopeptidase 9 (MMP9), Matrix Metallopeptidase 28 (MMP28) and TIMP Metallopeptidase Inhibitor 1 (TIMP1) in Colorectal Cancer: Assessment of the Role in Diagnosis and Prognostication.
Colorectal Neoplasms
Separation-Based Enzymomics Assay for the Discovery of Altered Peptide-Metabolizing Enzymatic Activities in Biosamples.
Colorectal Neoplasms
Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog.
Coronary Artery Disease
Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association Studies.
Coronary Disease
Association between matrix metallopeptidase 1 and type 2 diabetes mellitus coexisting with coronary heart disease in a Han Chinese population.
COVID-19
Counter-regulatory 'Renin-Angiotensin' System-based Candidate Drugs to Treat COVID-19 Diseases in SARS-CoV-2-infected patients.
Cross Infection
Structural Requirements of N-alpha-Mercaptoacetyl Dipeptide (NAMdP) Inhibitors of Pseudomonas Aeruginosa Virulence Factor LasB: 3D-QSAR, Molecular Docking, and Interaction Fingerprint Studies.
Dental Caries
Association of ENAM, TUFT1, MMP13, IL1B, IL10 and IL1RN gene polymorphism and dental caries susceptibility in Chinese children.
Diabetes Mellitus
Association between matrix metallopeptidase 1 and type 2 diabetes mellitus coexisting with coronary heart disease in a Han Chinese population.
Diabetes Mellitus, Type 2
Association between matrix metallopeptidase 1 and type 2 diabetes mellitus coexisting with coronary heart disease in a Han Chinese population.
Diabetic Foot
Effect of daptomycin on local interleukin-6, matrix metalloproteinase-9, and metallopeptidase inhibitor 1 in patients with MRSA-infected diabetic foot.
Diabetic Foot
Effect of Daptomycin on Local Interleukin-6, Matrix Metalloproteinase-9, and Metallopeptidase Inhibitor 1 in Patients With MRSA-Infected Diabetic Foot.
Endometrial Neoplasms
A dual tyrosine kinase inhibitor lapatinib suppresses overexpression of matrix metallopeptidase 1 (MMP1) in endometrial cancer.
Endometrial Neoplasms
Expression and clinical significance of ARTN and MMP-9 in endometrial carcinoma.
Endometriosis
Dysregulation of the ADAM17/Notch signalling pathways in endometriosis: from oxidative stress to fibrosis.
Endometriosis
Identification of global transcriptome abnormalities and potential biomarkers in eutopic endometria of women with endometriosis: A preliminary study.
Epilepsy
Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE).
Epilepsy, Temporal Lobe
Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE).
Esophageal Squamous Cell Carcinoma
The Sp1-mediaded allelic regulation of MMP13 expression by an ESCC susceptibility SNP rs2252070.
Familial Hypophosphatemic Rickets
Mepe, the gene encoding a tumor-secreted protein in oncogenic hypophosphatemic osteomalacia, is expressed in bone.
Fatty Liver
Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions.
Foot-and-Mouth Disease
Autophagic degradation of SQSTM1 inhibits ovarian cancer motility by decreasing DICER1 and AGO2 to induce MIRLET7A-3P.
Gingivitis
Salivary Biomarkers for Dental Caries Detection and Personalized Monitoring.
Glioblastoma
Girdin, an actin-binding protein, is critical for migration, adhesion, and invasion of human glioblastoma cells.
Glioma
Calcium modulates endopeptidase 24.15 (EC 3.4.24.15) membrane association, secondary structure and substrate specificity.
Glioma
CircMMP1 promotes the progression of glioma through miR-433/HMGB3 axis in vitro and in vivo.
Glioma
Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p.
Glioma
Forkhead box protein O3a promotes glioma cell resistance to temozolomide by regulating matrix metallopeptidase and ?-catenin.
Glioma
GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways.
Glioma
Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas.
Glioma
Regulation of C6 glioma cell migration by thymol.
Glioma
Single nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a Chinese han population.
Glomerulonephritis, Membranous
[The involvement of neprilysin in the pathogenesis of glomerulopathies]
Granuloma
Purification and properties of a peptidase acting on a synthetic substrate for collagenase from monkey kidney.
Heart Diseases
Molecular mechanism of miR-181b in heart disease due to pregnancy-induced hypertension syndrome.
Heart Diseases
Prioritizing potential ACE2 inhibitors in the COVID-19 pandemic: Insights from a molecular mechanics-assisted structure-based virtual screening experiment.
Hepatitis
Type III procollagen peptide and PZ-peptidase serum levels in pre-cirrhotic liver diseases.
Hepatitis, Alcoholic
Type III procollagen peptide and PZ-peptidase serum levels in pre-cirrhotic liver diseases.
Hepatitis, Chronic
Type III procollagen peptide and PZ-peptidase serum levels in pre-cirrhotic liver diseases.
Herpes Zoster
GPI-Anchored Protein Complex, LY6K/TEX101, Is Required for Sperm Migration into the Oviduct and Male Fertility in Mice.
Hyperalgesia
Metallopeptidase inhibition potentiates bradykinin-induced hyperalgesia.
Hyperalgesia
Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice.
Hypertension
Interactions between metallopeptidase 3 polymorphism rs679620 and BMI in predicting blood pressure in African-American women with hypertension.
Hypertension
Metalloendopeptidases EC 3.4.24.15 and EC 3.4.24.16 and bradykinin B2 receptors do not play important roles in renal wrap hypertension in rabbits.
Hypertension
MMP-9 and TIMP-1 in placenta of hypertensive disorder complicating pregnancy.
Hypertension
Structure-based pharmacophore design and virtual screening for novel Angiotensin converting enzyme 2 inhibitors.
Hypertension
The angiotensin-converting enzyme gene family: genomics and pharmacology.
Hypertension
Zinc metallopeptidase inhibitors. A novel antihypertensive treatment.
Hypertension, Pregnancy-Induced
MMP-9 and TIMP-1 in placenta of hypertensive disorder complicating pregnancy.
Hypophosphatemia
Expression and inactivation of osteopontin-degrading PHEX enzyme in squamous cell carcinoma.
Hypotension
A novel stable inhibitor of endopeptidases EC 3.4.24.15 and 3.4.24.16 potentiates bradykinin-induced hypotension.
Hypotension
Hemopressin: a novel bioactive peptide derived from the alpha1-chain of hemoglobin.
Infections
Anti-sense expression of a metallopeptidase gene enhances nuclear entry of HBV-DNA.
Infections
Assessment of a molecular diagnostic platform for integrated isolation and quantification of mRNA in whole blood.
Infections
Comparison of cytokine profiles induced by nonlethal and lethal doses of influenza A virus in mice.
Infections
Global gene expression profiles for life stages of the deadly amphibian pathogen Batrachochytrium dendrobatidis.
Infections
Influenza A virus lacking the effector and C terminal domains of NS1 protein induces cytokines associated with high pathogenicity in mice.
Infections
iTRAQ-based proteomics reveals novel members involved in pathogen challenge in sea cucumber Apostichopus japonicus.
Infections
Proteins involved in extracellular matrix dynamics are associated with RSV disease severity.
Infections
Transcriptional and Pathological Host Responses to Coinfection with Virulent or Attenuated Mycoplasma gallisepticum and Low-Pathogenic Avian Influenza A Virus in Chickens.
Inflammatory Bowel Diseases
Genetic variants of membrane metallopeptidase genes in inflammatory bowel diseases.
Inflammatory Bowel Diseases
Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog.
Insulin Resistance
The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity.
Insulin Resistance
Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions.
Kidney Diseases
CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling.
Kidney Failure, Chronic
Dysregulated gene expression of extracellular matrix and adhesion molecules in saphenous vein conduits of hemodialysis patients.
Leukemia
Stromal cell-mediated transcriptional regulation of the CD13/aminopeptidase N gene in leukemic cells.
Leukemia, Myeloid, Acute
Identification of acute myeloid leukemia patients with diminished expression of CD13 myeloid transcripts by competitive reverse transcription polymerase chain reaction (RT-PCR).
Leukemia, Myeloid, Acute
Stromal-mediated down-regulation of CD13 in bone marrow cells originating from acute myeloid leukemia patients.
Liver Cirrhosis
Association of novel markers of liver disease with neonatal liver disease in premature baboons, Papio sp.
Liver Cirrhosis
Protease profiling of liver fibrosis reveals the adam metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of TGF-?
Liver Cirrhosis
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-?1/Smads and PI3K/Akt pathways.
Liver Diseases
Association of novel markers of liver disease with neonatal liver disease in premature baboons, Papio sp.
Liver Diseases
Type III procollagen peptide and PZ-peptidase serum levels in pre-cirrhotic liver diseases.
Liver Neoplasms
Identification of the fatty acid synthase interaction network via iTRAQ-based proteomics indicates the potential molecular mechanisms of liver cancer metastasis.
Lordosis
Facilitation of lordosis in rats by a metabolite of luteinizing hormone releasing hormone.
Lung Diseases
Structure-based pharmacophore design and virtual screening for novel Angiotensin converting enzyme 2 inhibitors.
Lung Neoplasms
Expression of THOP1 and its relationship to prognosis in non-small cell lung cancer.
Lung Neoplasms
Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis.
Lymphatic Metastasis
Expression of THOP1 and its relationship to prognosis in non-small cell lung cancer.
Lymphatic Metastasis
Glucose-derived AGEs promote migration and invasion of colorectal cancer by up-regulating Sp1 expression.
Lymphatic Metastasis
High-resolution melting analysis of ADAMTS9 methylation levels in gastric, colorectal, and pancreatic cancers.
Lymphoma, B-Cell
Matrix Metallopeptidase 14: A Candidate Prognostic Biomarker for Diffuse Large B-Cell Lymphoma.
Lymphoma, Large B-Cell, Diffuse
Matrix Metallopeptidase 14: A Candidate Prognostic Biomarker for Diffuse Large B-Cell Lymphoma.
Malaria
Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum.
Malaria, Cerebral
Localised release of matrix metallopeptidase 8 in fatal cerebral malaria.
Melanoma
Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth.
Melanoma
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
Melanoma
Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells.
Melanoma
Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival.
Melanoma
Genome-Wide Characterization of Circulating Tumor Cells Identifies Novel Prognostic Genomic Alterations in Systemic Melanoma Metastasis.
Melanoma
Prenyl Ammonium Salts--New Carriers for Gene Delivery: A B16-F10 Mouse Melanoma Model.
Melanoma
Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma.
Melanoma
Silencing of astrocyte elevated gene-1 inhibits proliferation and migration of melanoma cells and induces apoptosis.
Melanoma
Targeting TGF-?-Mediated SMAD Signaling Pathway via Novel Recombinant Cytotoxin II: A Potent Protein from Naja naja oxiana Venom in Melanoma.
Memory Disorders
Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.
Metabolic Syndrome
ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1.
Migraine Disorders
Association of genetic loci for migraine susceptibility in the she people of China.
Mitochondrial Diseases
Amyloid-? in mitochondrial disease: mutation in a human metallopeptidase links amyloidotic neurodegeneration with mitochondrial processing.
Nasopharyngeal Carcinoma
High-resolution melting analysis of ADAMTS9 methylation levels in gastric, colorectal, and pancreatic cancers.
Neoplasm Metastasis
ADAMTS1, a putative anti-angiogenic factor, is decreased in human prostate cancer.
Neoplasm Metastasis
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
Neoplasm Metastasis
Design of Aminopeptidase N Inhibitors as Anti-cancer Agents.
Neoplasm Metastasis
Expression and clinical significance of ARTN and MMP-9 in endometrial carcinoma.
Neoplasm Metastasis
Expression of angiogenic factors is increased in metastasised renal cell carcinomas.
Neoplasm Metastasis
Expression of THOP1 and its relationship to prognosis in non-small cell lung cancer.
Neoplasm Metastasis
Fe3O4-solamargine induces apoptosis and inhibits metastasis of pancreatic cancer cells.
Neoplasm Metastasis
Filamin B extensively regulates transcription and alternative splicing, and is associated with apoptosis in HeLa cells.
Neoplasm Metastasis
Genome-Wide Characterization of Circulating Tumor Cells Identifies Novel Prognostic Genomic Alterations in Systemic Melanoma Metastasis.
Neoplasm Metastasis
Glucose-derived AGEs promote migration and invasion of colorectal cancer by up-regulating Sp1 expression.
Neoplasm Metastasis
High expression of Collagen Triple Helix Repeat Containing 1 (CTHRC1) facilitates progression of oesophageal squamous cell carcinoma through MAPK/MEK/ERK/FRA-1 activation.
Neoplasm Metastasis
High-resolution melting analysis of ADAMTS9 methylation levels in gastric, colorectal, and pancreatic cancers.
Neoplasm Metastasis
HP1? suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2.
Neoplasm Metastasis
Hypoxia-Inducible Factor-1? (HIF-1?) Promotes Hypoxia-Induced Invasion and Metastasis in Ovarian Cancer by Targeting Matrix Metallopeptidase 13 (MMP13).
Neoplasm Metastasis
Irradiation-induced dynamic changes of gene signatures reveal gain of metastatic ability in nasopharyngeal carcinoma.
Neoplasm Metastasis
Long non-coding RNA BRAF-regulated lncRNA 1 promotes lymph node invasion, metastasis and proliferation, and predicts poor prognosis in breast cancer.
Neoplasm Metastasis
Matrix Metallopeptidase 3 Polymorphisms: Emerging genetic Markers in Human Breast Cancer Metastasis.
Neoplasm Metastasis
Overexpression of matrix metalloproteinase 10 is associated with poor survival in patients with early stage of esophageal squamous cell carcinoma.
Neoplasm Metastasis
Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis.
Neoplasm Metastasis
Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer.
Neoplasm Metastasis
The omega-3 polyunsaturated fatty acid docosahexaenoic acid inhibits proliferation and progression of non-small cell lung cancer cells through the reactive oxygen species-mediated inactivation of the PI3K /Akt pathway.
Neoplasm Metastasis
Upregulation of Tubulointerstitial nephritis antigen like 1 promotes gastric cancer growth and metastasis by regulating multiple matrix metallopeptidase expression.
Neoplasm Metastasis
[Study on association between single nucleotide polymorphisms of MMP7, MMP8, MMP9 genes and development of gastric cancer and lymph node metastasis].
Neoplasms
A combinational approach to restore cytokine balance and to inhibit virus growth may promote patient recovery in severe COVID-19 cases.
Neoplasms
ADAMTS8 Inhibits Cell Proliferation and Invasion, and Induces Apoptosis in Breast Cancer.
Neoplasms
ADAMTS8 Inhibits Progression of Esophageal Squamous Cell Carcinoma.
Neoplasms
ADAMTS8 targets ERK to suppress cell proliferation, invasion, and metastasis of hepatocellular carcinoma.
Neoplasms
Altered glutamyl-aminopeptidase activity and expression in renal neoplasms.
Neoplasms
Antitumor effects and mechanisms of CpG ODN combined with attenuated Salmonella-delivered siRNAs against PD-1.
Neoplasms
Assessment of the Immunomodulatory Properties of the Probiotic Strain Lactobacillus paracasei K5 in vitro and In Vivo.
Neoplasms
Association of the invasiveness of colon cancer with the expression of C/EBP?.
Neoplasms
Azilsartan prevented AGE-induced inflammatory response and degradation of aggrecan in human chondrocytes through inhibition of Sox4.
Neoplasms
Blind SELEX Approach Identifies RNA Aptamers That Regulate EMT and Inhibit Metastasis.
Neoplasms
Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion.
Neoplasms
Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth.
Neoplasms
Clinical relevance of serum levels of matrix metallopeptidase-2, and tissue inhibitor of metalloproteinase-1 and -2 in patients with malignant melanoma.
Neoplasms
Combined Inflammation and Metabolism Biomarker Indices of Robust and Impaired Physical Function in Older Adults.
Neoplasms
Complement factor I upregulates expression of matrix metalloproteinase-13 and -2 and promotes invasion of cutaneous squamous carcinoma cells.
Neoplasms
Design of Aminopeptidase N Inhibitors as Anti-cancer Agents.
Neoplasms
Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma.
Neoplasms
Effect of recombinant human IFN? in the treatment of chronic pulmonary complications due to sulfur mustard intoxication.
Neoplasms
Effects of C-myc gene silencing on interleukin-1?-induced rat chondrocyte cell proliferation, apoptosis and cytokine expression.
Neoplasms
Elevated synovial fluid IL-33 and IL-6 levels and cartilage degeneration in stage III osteonecrosis of the femoral head.
Neoplasms
Expression and clinical significance of ARTN and MMP-9 in endometrial carcinoma.
Neoplasms
Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets.
Neoplasms
Fe3O4-solamargine induces apoptosis and inhibits metastasis of pancreatic cancer cells.
Neoplasms
Fermented goat milk consumption improves cardiovascular health during anemia recovery.
Neoplasms
Fine particulate matter exposure promotes M2 macrophage polarization through inhibiting histone deacetylase 2 in the pathogenesis of chronic obstructive pulmonary disease.
Neoplasms
Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT.
Neoplasms
Gamma Radiation-Attenuated Toxoplasma gondii Provokes Apoptosis in Ehrlich Ascites Carcinoma-Bearing Mice Generating Long-Lasting Immunity.
Neoplasms
Gene Expression Analysis Identifies Novel Targets for Cervical Cancer Therapy.
Neoplasms
Gene expression analysis in induced sputum from welders with and without airway-related symptoms.
Neoplasms
Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival.
Neoplasms
High LINC01605 expression predicts poor prognosis and promotes tumor progression via up-regulation of MMP9 in bladder cancer.
Neoplasms
High-resolution melting analysis of ADAMTS9 methylation levels in gastric, colorectal, and pancreatic cancers.
Neoplasms
HP1? suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2.
Neoplasms
Identification of molecular phenotypic descriptors of breast capsular contracture formation using informatics analysis of the whole genome transcriptome.
Neoplasms
Identification of Prognostic Stromal-Immune Score-Based Genes in Hepatocellular Carcinoma Microenvironment.
Neoplasms
Increased airway T lymphocyte microparticles in chronic obstructive pulmonary disease induces airway epithelial injury.
Neoplasms
Insulin receptor substrate 1 regulates the cellular differentiation and the matrix metallopeptidase expression of preosteoblastic cells.
Neoplasms
Integrated analysis identifies a long non-coding RNAs-messenger RNAs signature for prediction of prognosis in hepatitis B virus-hepatocellular carcinoma patients.
Neoplasms
Interleukin-26 promotes the proliferation and activation of hepatic stellate cells to exacerbate liver fibrosis by the TGF-?1/Smad2 signaling pathway.
Neoplasms
Involvement of TIMP-1 in PECAM-1-mediated tumor dissemination.
Neoplasms
Keratinocyte autophagy enables the activation of keratinocytes and fibroblasts and facilitates wound healing.
Neoplasms
Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells.
Neoplasms
LPS?induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF??B, STAT3 or AP?1 activation.
Neoplasms
Medroxyprogesterone Reverses Tolerable Dose Metformin-Induced Inhibition of Invasion via Matrix Metallopeptidase-9 and Transforming Growth Factor-?1 in KLE Endometrial Cancer Cells.
Neoplasms
Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas.
Neoplasms
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Neoplasms
NF-?B and STAT3 cooperatively induce IL6 in starved cancer cells.
Neoplasms
Notch1a can widely mediate innate immune responses in zebrafish larvae infected with Vibrio parahaemolyticus.
Neoplasms
Overexpression of matrix metalloproteinase 10 is associated with poor survival in patients with early stage of esophageal squamous cell carcinoma.
Neoplasms
p53 is required for cisplatin-induced processing of the mitochondrial fusion protein L-Opa1 that is mediated by the mitochondrial metallopeptidase Oma1 in gynecologic cancers.
Neoplasms
Polymorphism of angiotensin I-converting enzyme gene is related to oral cancer and lymph node metastasis in male betel quid chewers.
Neoplasms
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Neoplasms
Preclinical toxicity, toxicokinetics, and antitumoral efficacy studies of DTS-201, a tumor-selective peptidic prodrug of doxorubicin.
Neoplasms
Prenyl Ammonium Salts--New Carriers for Gene Delivery: A B16-F10 Mouse Melanoma Model.
Neoplasms
Prevention of melamine-induced hepatorenal impairment by an ethanolic extract of Moringa oleifera: Changes in KIM-1, TIMP-1, oxidative stress, apoptosis, and inflammation-related genes.
Neoplasms
Production of an antigenic peptide by insulin-degrading enzyme.
Neoplasms
Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma.
Neoplasms
RASSF1A Promoter Methylation Levels Positively Correlate with Estrogen Receptor Expression in Breast Cancer Patients.
Neoplasms
Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).
Neoplasms
Shenkang VII Recipe Attenuates Unilateral Ureteral Obstruction-induced Renal Fibrosis via TGF-?/Smad, NF-?B and SHH Signaling Pathway.
Neoplasms
Six cases of perforating pilomatricoma: Anetodermic changes with expression of matrix metalloproteinases.
Neoplasms
Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis.
Neoplasms
Structural and Biochemical Characterization of a Novel Aminopeptidase from Human Intestine.
Neoplasms
Structural basis for the sheddase function of human meprin ? metalloproteinase at the plasma membrane.
Neoplasms
Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation.
Neoplasms
The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion.
Neoplasms
The effect of different species aminopeptidase N structure on the activity screening of aminopeptidase N inhibitor.
Neoplasms
The effect of vascular endothelial growth factor (VEGF) on mouse condylar articular cartilage cultured in vitro.
Neoplasms
The role of neuropeptide processing enzymes in endocrine (prostate) cancer: EC 3.4.24.15 (EP24.15).
Neoplasms
Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization.
Neoplasms
Transcriptomic analysis of adhesive capsulitis of the shoulder.
Neoplasms
Tumour necrosis factor receptor-associated factors: interacting protein with forkhead-associated domain inhibition decreases inflammatory cell infiltration and cardiac remodelling after acute myocardial infarction.
Neoplasms
Whole genome expression profiling and screening for differentially expressed cytokine genes in human bone marrow endothelial cells treated with humoral inhibitors in liver cirrhosis.
Neoplasms
[Expressions of inflammatory and fibrogenic factors in perinephric and subcutaneous adipose tissues of patients with adrenocorticotropic hormone-independent Cushing's syndrome].
Neoplasms
[Study on association between single nucleotide polymorphisms of MMP7, MMP8, MMP9 genes and development of gastric cancer and lymph node metastasis].
Nephritis, Interstitial
Upregulation of Tubulointerstitial nephritis antigen like 1 promotes gastric cancer growth and metastasis by regulating multiple matrix metallopeptidase expression.
Neurogenic Inflammation
Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patients.
Non-alcoholic Fatty Liver Disease
Oxaliplatin aggravates hepatic oxidative stress, inflammation and fibrosis in a non?alcoholic fatty liver disease mouse model.
Non-alcoholic Fatty Liver Disease
Validation of Serum Test for Advanced Liver Fibrosis in Patients with Nonalcoholic Steatohepatitis.
Obesity
The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity.
Obesity
Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions.
Osteoarthritis
Design, cyclization, and optimization of MMP13-TIMP1 interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis.
Osteoarthritis
Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice.
Osteoarthritis
Expression of exosomal microRNAs during chondrogenic differentiation of human bone mesenchymal stem cells.
Osteoarthritis
Fibroblast growth factor 18 exerts anti-osteoarthritic effects through PI3K-AKT signaling and mitochondrial fusion and fission.
Osteoarthritis
Regulatory effect of anti-gp130 functional mAb on IL-6 mediated RANKL and Wnt5a expression through JAK-STAT3 signaling pathway in FLS.
Osteoarthritis, Knee
Effect of low intensity pulsed ultrasound on expression of TIMP-2 in serum and expression of mmp-13 in articular cartilage of rabbits with knee osteoarthritis.
Osteosarcoma
Differential expression of degradome components in cutaneous squamous cell carcinomas.
Osteosarcoma
MicroRNA-29b sensitizes osteosarcoma cells to doxorubicin by targeting matrix metalloproteinase 9 (MMP-9) in osteosarcoma.
Osteosarcoma
Single nucleotide polymorphisms from candidate genes associated with nematode resistance and resilience in Corriedale and Pampinta sheep in Argentina.
Ovarian Neoplasms
Hypoxia-Inducible Factor-1? (HIF-1?) Promotes Hypoxia-Induced Invasion and Metastasis in Ovarian Cancer by Targeting Matrix Metallopeptidase 13 (MMP13).
Ovarian Neoplasms
Identification of Candidate Genes Associated with Chemotherapy Resistance in Ovarian Cancer.
Ovarian Neoplasms
MicroRNA-16 inhibits migration and invasion via regulation of the Wnt/?-catenin signaling pathway in ovarian cancer.
Pancreatitis, Chronic
Substance P and neprilysin in chronic pancreatitis.
Pre-Eclampsia
Mid-Trimester Maternal ADAM12 Levels Differ According to Fetal Gender in Pregnancies Complicated by Preeclampsia.
Pre-Eclampsia
MMP-14 aggravates onset of severe preeclampsia by mediating soluble endoglin release.
Pre-Eclampsia
[Effect of microRNA-106b on the invasion and proliferation of trophoblasts through targeting MMP-2].
Pre-Eclampsia
[Microarray analysis of differentially expressed genes in peripheral leucocytes derived from severe preeclampsia and normotensive pregnancies]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Development of [125I]RB104, a potent inhibitor of neutral endopeptidase 24.11, and its use in detecting nanogram quantities of the enzyme by "inhibitor gel electrophoresis".
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Immunohistochemical Expression of CD10 in Cutaneous Basal and Squamous Cell Carcinomas.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Immunohistochemical expression of CD10 in cutaneous basal and squamous cell carcinomas.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Increased expression of neprilysin (neutral endopeptidase 24.11) in rat and human hepatocellular carcinomas.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Stromal cell-mediated transcriptional regulation of the CD13/aminopeptidase N gene in leukemic cells.
Primary Ovarian Insufficiency
Epistasis between polymorphisms in ACVR2B and ADAMTS19 is associated with premature ovarian failure.
Primary Ovarian Insufficiency
Epistasis between polymorphisms in TSHB and ADAMTS16 is associated with premature ovarian failure.
Progeria
Dysfunction of iPSC-derived endothelial cells in human Hutchinson-Gilford progeria syndrome.
Prostatic Neoplasms
ADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumors.
Prostatic Neoplasms
ADAMTS1, a putative anti-angiogenic factor, is decreased in human prostate cancer.
Prostatic Neoplasms
Dual specificity phosphatase 6 suppresses the growth and metastasis of prostate cancer cells.
Prostatic Neoplasms
High CD10 expression in lymph node metastases from surgically treated prostate cancer independently predicts early death.
Prostatic Neoplasms
Is prostate-specific membrane antigen a multifunctional protein?
Prostatic Neoplasms
Melatonin impedes prostate cancer metastasis by suppressing MMP-13 expression.
Prostatic Neoplasms
Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression.
Prostatic Neoplasms
The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells.
Prostatic Neoplasms
The role of neuropeptide processing enzymes in endocrine (prostate) cancer: EC 3.4.24.15 (EP24.15).
Prostatic Neoplasms
What to Trust, PSA or [68Ga]Ga-PSMA-11: Learn from Experience.
Pulmonary Disease, Chronic Obstructive
Effect of recombinant human IFN? in the treatment of chronic pulmonary complications due to sulfur mustard intoxication.
Pulmonary Disease, Chronic Obstructive
Fine particulate matter exposure promotes M2 macrophage polarization through inhibiting histone deacetylase 2 in the pathogenesis of chronic obstructive pulmonary disease.
Purpura, Thrombocytopenic
How do we reduce plasma transfusion in Rhode Island?
Purpura, Thrombotic Thrombocytopenic
Successful management of pregnancy-associated thrombotic thrombocytopenic purpura by monitoring ADAMTS13 activity.
Respiratory Hypersensitivity
ADAM metallopeptidase domain 33 (ADAM33): identification and role in airways disease.
Rheumatic Diseases
Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patients.
Sarcoma
ESR1 mediated circ_0004018 suppresses angiogenesis in hepatocellular carcinoma via recruiting FUS and stabilizing TIMP2 expression.
Sarcoma
Identification of AFAP1L1 as a prognostic marker for spindle cell sarcomas.
Sarcoma
In vivo imaging of cell proliferation in meningioma using 3'-deoxy-3'-[18F]fluorothymidine PET/MRI.
Seizures
Pentylenetetrazol-induced seizures affect the levels of prolyl oligopeptidase, thimet oligopeptidase and glial proteins in rat brain regions, and attenuation by MK-801 pretreatment.
Sepsis
Systemic inflammation and protease profile of Afro-Caribbean patients with sepsis.
Severe Acute Respiratory Syndrome
ACE2 (Angiotensin-Converting Enzyme 2) in Cardiopulmonary Diseases: Ramifications for the Control of SARS-CoV-2.
Sleep Deprivation
Sleep deprivation changes thimet oligopeptidase (THOP1) expression and activity in rat brain.
Spastic Paraplegia, Hereditary
Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia.
Stomach Neoplasms
Clinical utility of measuring expression levels of KAP1, TIMP1 and STC2 in peripheral blood of patients with gastric cancer.
Stomach Neoplasms
Downregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer.
Stomach Neoplasms
High expression of ghrelin and obestatin prepropeptide in tumor tissues predicted adverse overall survival in gastric carcinoma patients.
Stomach Neoplasms
KLK6 Promotes Growth, Migration, and Invasion of Gastric Cancer Cells.
Stomach Neoplasms
Upregulation of Tubulointerstitial nephritis antigen like 1 promotes gastric cancer growth and metastasis by regulating multiple matrix metallopeptidase expression.
Tetanus
Beta-amino-thiols inhibit the zinc metallopeptidase activity of tetanus toxin light chain.
Tetanus
Metallopeptidase inhibitors of tetanus toxin: A combinatorial approach.
Thrombosis
Activities of proteases in parietal thrombus of aortic aneurysm.
Thyroid Cancer, Papillary
miR-214 regulates papillary thyroid carcinoma cell proliferation and metastasis by targeting PSMD10.
Thyroid Cancer, Papillary
Role of gene expression profiling in defining indeterminate thyroid nodules in addition to BRAF analysis.
Toxoplasmosis
Toxoplasma gondii: purification and characterization of an immunogenic metallopeptidase.
Tuberculosis
Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates.
Ureteral Obstruction
Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13-Mediated Matrix Degradation.
Urinary Bladder Neoplasms
Analytical validation of ONCURIA a multiplex bead-based immunoassay for the non-invasive bladder cancer detection.
Urinary Bladder Neoplasms
microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer.
Uterine Cervical Neoplasms
Matrix Metallopeptidase 14 Plays an Important Role in Regulating Tumorigenic Gene Expression and Invasion Ability of HeLa Cells.
Vascular System Injuries
Endothelial cells recruit macrophages and contribute to a fibrotic milieu in Bleomycin lung injury.
Wilms Tumor
Long Noncoding RNA DUXAP8 Promotes Pancreatic Carcinoma Cell Migration and Invasion Via Pathway by miR-448/WTAP/Fak Signaling Axis.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Thompson, A.; Grueninger-Leitch, F.; Huber, G.; Malherbe, P.
Expression and characterization of human beta-secretase candidates metalloendopeptidase MP78 and cathepsin D in beta APP-overexpressing cells
Mol. Brain Res.
48
206-214
1997
Homo sapiens
brenda
Knight, C.G.; Dando, P.M.; Barrett, A.J.
Thimet oligopeptidase specificity: evidence of preferential cleavage near the C-terminus and product inhibition from kinetic analysis of peptide hydrolysis
Biochem. J.
308
145-150
1995
Homo sapiens
brenda
Barrett, A.J.; Brown, M.A.; Dando, P.M.; Knight, C.G.; McKie, N.; Rawlings, N.D.; Serizawa, A.
Thimet oligopeptidase and oligopeptidase M or neurolysin
Methods Enzymol.
248
529-556
1995
Homo sapiens, Rattus norvegicus
brenda
Saric, T.; Beninga, J.; Graef, C.I.; Akopian, T.N.; Rock, K.L.; Goldberg, A.L.
Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase
J. Biol. Chem.
276
36474-36481
2001
Homo sapiens
brenda
Ray, K.; Hines, C.S.; Coll-Rodriguez, J.; Rodgers, D.W.
Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization
J. Biol. Chem.
279
20480-20489
2004
Homo sapiens
brenda
Shivakumar, B.R.; Wang, Z.; Hammond, T.G.; Harris, R.C.
EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor
Cell Biochem. Funct.
23
195-204
2005
Homo sapiens
brenda
Dubois, V.; Nieder, M.; Collot, F.; Negrouk, A.; Nguyen, T.T.; Gangwar, S.; Reitz, B.; Wattiez, R.; Dasnois, L.; Trouet, A.
Thimet oligopeptidase (EC 3.4.24.15) activates CPI-0004Na, an extracellularly tumour-activated prodrug of doxorubicin
Eur. J. Cancer
42
3049-3056
2006
Homo sapiens
brenda
Saric, T.; Graef, C.I.; Goldberg, A.L.
Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases
J. Biol. Chem.
279
46723-46732
2004
Homo sapiens, Rattus norvegicus
brenda
Lim, E.J.; Sampath, S.; Coll-Rodriguez, J.; Schmidt, J.; Ray, K.; Rodgers, D.W.
Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidase
J. Biol. Chem.
282
9722-9732
2007
Homo sapiens
brenda
Sanden, C.; Enquist, J.; Bengtson, S.H.; Herwald, H.; Leeb-Lundberg, F.L.
Kinin B2 receptor-mediated bradykinin internalization and metalloendopeptidase EP24.15-dependent intracellular bradykinin degradation
J. Pharmacol. Exp. Ther.
326
24-32
2008
Homo sapiens
brenda
Kitabgi, P.
Inactivation of neurotensin and neuromedin N by Zn metallopeptidases
Peptides
27
2515-2522
2006
Canis lupus familiaris, Homo sapiens, Mus musculus
brenda
Machado, M.F.; Marcondes, M.F.; Rioli, V.; Ferro, E.S.; Juliano, M.A.; Juliano, L.; Oliveira, V.
Catalytic properties of thimet oligopeptidase H600A mutant
Biochem. Biophys. Res. Commun.
394
429-433
2010
Homo sapiens
brenda
Russo, L.C.; Goni, C.N.; Castro, L.M.; Asega, A.F.; Camargo, A.C.; Trujillo, C.A.; Ulrich, H.; Glucksman, M.J.; Scavone, C.; Ferro, E.S.
Interaction with calmodulin is important for the secretion of thimet oligopeptidase following stimulation
FEBS J.
276
4358-4371
2009
Homo sapiens, Mus musculus
brenda
Kessler, J.H.; Khan, S.; Seifert, U.; Le Gall, S.; Chow, K.M.; Paschen, A.; Bres-Vloemans, S.A.; de Ru, A.; van Montfoort, N.; Franken, K.L.; Benckhuijsen, W.E.; Brooks, J.M.; van Hall, T.; Ray, K.; Mulder, A.; Doxiadis, I.I.; van Swieten, P.F.; Overkleeft, H.S.; Prat, A.; Tomkinson, B.; Neefjes, J.; Klo, K.l.o.e.
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
Nat. Immunol.
12
45-53
2011
Homo sapiens
brenda
Guinan, A.F.; Rochfort, K.D.; Fitzpatrick, P.A.; Walsh, T.G.; Pierotti, A.R.; Phelan, S.; Murphy, R.P.; Cummins, P.M.
Shear stress is a positive regulator of thimet oligopeptidase (EC3.4.24.15) in vascular endothelial cells: consequences for MHC1 levels
Cardiovasc. Res.
99
545-554
2013
Homo sapiens (P52888), Bos taurus (Q1JPJ8)
brenda
Simoes, P.S.; Visniauskas, B.; Perosa, S.R.; Yacubian, E.M.; Centeno, R.; Canzian, M.; Lopes-Cendes, I.; Maurer Morelli, C.V.; Carrete, H.; Cavalheiro, E.A.; Tufik, S.; Chagas, J.R.; Mazzacoratti, M.d.a..G.
Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE)
Epilepsia
55
754-762
2014
Rattus norvegicus (P24155), Homo sapiens (P52888), Homo sapiens
brenda
Ferreira, J.C.; Icimoto, M.Y.; Marcondes, M.F.; Oliveira, V.; Nascimento, O.R.; Nantes, I.L.
Recycling of the high valence States of heme proteins by cysteine residues of THIMET-oligopeptidase
PLoS ONE
8
e79102
2013
Homo sapiens (P52888)
brenda
Icimoto, M.Y.; Ferreira, J.C.; Yokomizo, C.H.; Bim, L.V.; Marem, A.; Gilio, J.M.; Oliveira, V.; Nantes, I.L.
Redox modulation of thimet oligopeptidase activity by hydrogen peroxide
FEBS Open Bio
7
1037-1050
2017
Rattus norvegicus (P24155), Homo sapiens (P52888), Homo sapiens
brenda
3.4.24.15 thimet oligopeptidase
more
top
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
