Disease on EC 3.4.24.1 - atrolysin A
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Abortion, Missed
Maternal serum disintegrin and metalloprotease protein-12 in early pregnancy as a potential marker of adverse pregnancy outcomes.
Abortion, Spontaneous
Biological potentials for a family of disintegrin and metalloproteinase (ADAMDEC)-1 in mouse normal pregnancy.
Abortion, Spontaneous
Maternal serum disintegrin and metalloprotease protein-12 in early pregnancy as a potential marker of adverse pregnancy outcomes.
Acute Coronary Syndrome
ADAMTS4 level in patients with stable coronary artery disease and acute coronary syndromes.
Acute Kidney Injury
MicroRNA-874-3p/ADAM (A Disintegrin and Metalloprotease) 19 Mediates Macrophage Activation and Renal Fibrosis After Acute Kidney Injury.
Acute Kidney Injury
Three Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.
Acute Lung Injury
Preventing cleavage of Mer promotes efferocytosis and suppresses acute lung injury in bleomycin treated mice.
adamts13 endopeptidase deficiency
ADAMTS13 Gene Mutations Influence ADAMTS13 Conformation and Disease Age-Onset in the French Cohort of Upshaw-Schulman Syndrome.
adamts13 endopeptidase deficiency
Anti-ADAMTS13 autoantibody profiling in patients with immune-mediated thrombotic thrombocytopenic purpura.
adamts13 endopeptidase deficiency
Child-onset and adolescent-onset acquired thrombotic thrombocytopenic purpura with severe ADAMTS13 deficiency: a cohort study of the French national registry for thrombotic microangiopathy.
Adenocarcinoma
Aberrant Expression of a Disintegrin and Metalloproteinase 17/Tumor Necrosis Factor-{alpha} Converting Enzyme Increases the Malignant Potential in Human Pancreatic Ductal Adenocarcinoma.
Adenocarcinoma
Anti-invasive and anti-adhesive activities of a recombinant disintegrin, r-viridistatin 2, derived from the Prairie rattlesnake (Crotalus viridis viridis).
Adenocarcinoma
Disintegrin and metalloproteinases (ADAMs) expression in gastroesophageal reflux disease and in esophageal adenocarcinoma.
Adenocarcinoma
Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas.
Adenocarcinoma
PGF2?-F-prostanoid receptor signalling via ADAMTS1 modulates epithelial cell invasion and endothelial cell function in endometrial cancer.
Adenocarcinoma of Lung
Lentivirus-mediated disintegrin and metalloproteinase 17 RNA interference reversed the acquired resistance to gefitinib in lung adenocarcinoma cells in vitro.
Adenocarcinoma of Lung
Lysophosphatidic acid-induced ADAM12 expression mediates human adipose tissue-derived mesenchymal stem cell-stimulated tumor growth.
Adenocarcinoma of Lung
MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9).
Adenomatous Polyposis Coli
Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury.
Adenomatous Polyposis Coli
CXCL12 and ADAM23 hypermethylation are associated with advanced breast cancers.
Alzheimer Disease
A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10.
Alzheimer Disease
Comparative localization of ADAMs 10 and 15 in human cerebral cortex normal aging, Alzheimer disease and Down syndrome.
Alzheimer Disease
Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.
Alzheimer Disease
Genetic association between ADAM10 gene polymorphism and Alzheimer's disease in a Northern Han Chinese population.
Alzheimer Disease
Octyl Gallate Markedly Promotes Anti-Amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation.
Alzheimer Disease
Platelet a disintegrin and metallopeptidase 10 expression correlates with clock drawing test scores in Alzheimer's disease.
Alzheimer Disease
Sulfuretin exerts diversified functions in the processing of amyloid precursor protein.
Alzheimer Disease
Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.
Alzheimer Disease
The Role of the Anti-Amyloidogenic Secretase ADAM10 in Shedding the APP-Like Proteins.
Alzheimer Disease
Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region.
Alzheimer Disease
Variation at the ADAM10 gene locus is not associated with Creutzfeldt-Jakob disease.
Anemia, Hemolytic
Caplacizumab to treat immune-mediated thrombotic thrombocytopenic purpura.
Anemia, Hemolytic
Current management and therapeutical perspectives in thrombotic thrombocytopenic purpura.
Anemia, Hemolytic
Infection as Trigger for Congenital Thrombotic Thrombocytopenic Purpura in an Adult Patient.
Anemia, Hemolytic
Relapse Rate in Survivors of Acute Autoimmune Thrombotic Thrombocytopenic Purpura Treated with or without Rituximab.
Anemia, Hemolytic
Utilizing a PLASMIC score-based approach in the management of suspected immune thrombotic thrombocytopenic purpura: a cost minimization analysis within the Harvard TMA Research Collaborative.
Anemia, Hemolytic
What's new in the diagnosis and pathophysiology of thrombotic thrombocytopenic purpura.
Anemia, Sickle Cell
Absence of exaggerated pharmacology by recombinant ADAMTS13 in the rat and monkey.
Aneurysm, Dissecting
A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection.
Aneurysm, Dissecting
A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection.
Antiphospholipid Syndrome
Double positivity of anti-?2-glycoprotein I domain I and anti-phosphatidylserine/prothrombin antibodies enhances both thrombosis and positivity of anti-ADAMTS13 antibody.
Aortic Aneurysm, Abdominal
ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm.
Aortic Aneurysm, Abdominal
Expression of a disintegrin and metalloprotease in human abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
Role of ADAM9 and miR-126 in the development of abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
Ursolic acid prevents angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice.
Aortic Aneurysm, Abdominal
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/?-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.
Aortic Aneurysm, Thoracic
Elevation of ADAM10, ADAM17, MMP-2 and MMP-9 expression with media degeneration features CaCl2-induced thoracic aortic aneurysm in a rat model.
Aortic Aneurysm, Thoracic
The Investigation of a Disintegrin and Metalloproteinase with ThromboSpondin Motifs (ADAMTS) 1, 5 and 16 in Thoracic Aortic Aneurysms and Dissections.
Arthritis
ADAM8 substrate specificity: Influence of pH on pre-processing and proteoglycan degradation.
Arthritis
ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis.
Arthritis
ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse.
Arthritis
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.
Arthritis
Feprazone Ameliorates TNF-?-Induced Loss of Aggrecan via Inhibition of the SOX-4/ADAMTS-5 Signaling Pathway.
Arthritis
Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption.
Arthritis
Interleukin-1 Induction of Aggrecanase Gene Expression in Human Articular Chondrocytes is Mediated by Mitogen-Activated Protein Kinases.
Arthritis
Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis.
Arthritis
Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8).
Arthritis
Role of Sp1 transcription factor in Interleukin-1-induced ADAMTS-4 (aggrecanase-1) gene expression in human articular chondrocytes.
Arthritis
The interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis.
Arthritis
The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities.
Arthritis
The t(14,15) in mouse strain CBA/CaH-T(14;15)6Ca/J causes a break in the ADAMTS12 gene.
Arthritis, Rheumatoid
A Disintegrin and Metalloprotease 15 is Expressed on Rheumatoid Arthritis Synovial Tissue Endothelial Cells and may Mediate Angiogenesis.
Arthritis, Rheumatoid
A disintegrin and metalloprotease-10 is correlated with disease activity and mediates monocyte migration and adhesion in rheumatoid arthritis.
Arthritis, Rheumatoid
A disintegrin and metalloproteinase (ADAM)-10 as a predictive factor for tocilizumab effectiveness in rheumatoid arthritis.
Arthritis, Rheumatoid
A disintegrin and metallproteinase 15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis.
Arthritis, Rheumatoid
A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17.
Arthritis, Rheumatoid
ADAM15 adds to apoptosis resistance of synovial fibroblasts by modulating focal adhesion kinase signaling.
Arthritis, Rheumatoid
ADAMTS4 (aggrecanase-1) interaction with the C-terminal domain of fibronectin inhibits proteolysis of aggrecan.
Arthritis, Rheumatoid
ADAMTS5 is a biomarker for prediction of response to infliximab in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Glycosylation of a disintegrin and metalloprotease 17 affects its activity and inhibition.
Arthritis, Rheumatoid
Highly enhanced expression of the disintegrin metalloproteinase MDC15 (metargidin) in rheumatoid synovial tissue.
Arthritis, Rheumatoid
Interleukin-4 antagonizes oncostatin M and transforming growth factor beta-induced responses in articular chondrocytes.
Arthritis, Rheumatoid
Involvement of a disintegrin and a metalloproteinase 8 (ADAM8) in osteoclastogenesis and pathological bone destruction.
Arthritis, Rheumatoid
Leptin induces ADAMTS-4, ADAMTS-5, and ADAMTS-9 genes expression by mitogen-activated protein kinases and NF-?B signaling pathways in human chondrocytes.
Arthritis, Rheumatoid
Neutralization of ADAM8 ameliorates liver injury and accelerates liver repair in carbon tetrachloride-induced acute liver injury.
Arthritis, Rheumatoid
Nobiletin, a citrus polymethoxy flavonoid, suppresses gene expression and production of aggrecanases-1 and -2 in collagen-induced arthritic mice.
Arthritis, Rheumatoid
Novel functions of inactive rhomboid proteins in immunity and disease.
Asthma
A disintegrin and metalloprotease 33 (ADAM33) gene polymorphisms and the risk of asthma: A meta-analysis.
Asthma
A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population.
Asthma
A disintegrin and metalloproteinase 33 protein in patients with asthma: Relevance to airflow limitation.
Asthma
A novel peptide ADAM8 inhibitor attenuates bronchial hyperresponsiveness and Th2 cytokine mediated inflammation of murine asthmatic models.
Asthma
A Six-SNP haplotype of ADAM33 is associated with asthma in a population of Cartagena, Colombia.
Asthma
ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma.
Asthma
ADAM metallopeptidase domain 33 (ADAM33): identification and role in airways disease.
Asthma
ADAM33 gene polymorphisms associate with asthma susceptibility and severity in East China han population.
Asthma
ADAM33 gene polymorphisms identified to be associated with asthma in a Chinese Li population.
Asthma
ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice.
Asthma
ADAM33 polymorphisms are associated with asthma and a distinctive palm dermatoglyphic pattern.
Asthma
ADAM33 polymorphisms are associated with asthma susceptibility in a Japanese population.
Asthma
ADAM33 polymorphisms, smoking and asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health Study.
Asthma
ADAM33 protein expression and the mechanics of airway smooth muscle cells are highly correlated in ovalbumin-sensitized rats.
Asthma
ADAM8 substrate specificity: Influence of pH on pre-processing and proteoglycan degradation.
Asthma
Association between ADAM33 polymorphisms and adult asthma in the Japanese population.
Asthma
Association between ADAM33 polymorphisms and asthma risk: a systematic review and meta-analysis.
Asthma
Association between ADAM33 polymorphisms and susceptibility with adult and childhood asthma among Jordanians.
Asthma
Association between ADAM33 S2 and ST+4 polymorphisms and susceptibility to asthma: a meta-analysis.
Asthma
Association between polymorphisms in ADAM33, CD14, and TLR4 with asthma in the Uygur population in China.
Asthma
Association between V4 polymorphism in the ADAM33 gene and asthma risk: a meta-analysis.
Asthma
Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations.
Asthma
Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population.
Asthma
Association of ADAM33 gene polymorphisms with adult-onset asthma and its severity in an Indian adult population.
Asthma
Association of ADAM33 gene polymorphisms with asthma in Mongolian and Han groups in Inner Mongolia.
Asthma
Association of ADAM33 gene polymorphisms with asthma in the Uygur population of China.
Asthma
Association of ADAM33 gene polymorphisms with COPD in a northeastern Chinese population.
Asthma
Association of ADAM33 polymorphisms with childhood asthma in a northern Chinese population.
Asthma
Association of matrix metalloproteinase 8 genetic polymorphisms with bronchial asthma in a Japanese population.
Asthma
Diversity of asthma: evolving concepts of pathophysiology and lessons from genetics.
Asthma
Downregulation of a disintegrin and metalloproteinase 33 by IFN-gamma in human airway smooth muscle cells.
Asthma
Effect of active vitamin D3 on VEGF-induced ADAM33 expression and proliferation in human airway smooth muscle cells: implications for asthma treatment.
Asthma
Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells.
Asthma
Expression and regulation of a disintegrin and metalloproteinase (ADAM) 8 in experimental asthma.
Asthma
Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci.
Asthma
Frequency of genetic polymorphisms of ADAM33 and their association with allergic rhinitis among Jordanians.
Asthma
Genetic association of ADAM33 polymorphisms with childhood asthma in Chinese Han population: A case-control study.
Asthma
Genetic polymorphisms and asthma: findings from a case-control study in the Madeira island population.
Asthma
Genetic variants of ADAM33 are associated with asthma susceptibility in the Punjabi population of Pakistan.
Asthma
IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migration.
Asthma
Increased serum ADAM8 concentration in patients with drug-induced eosinophilic pneumonia-ADAM8 expression depends on a the allergen route of entry.
Asthma
Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy.
Asthma
Investigating the Association of ADAM33 Single Nucleotide Polymorphisms (SNPs) with Susceptibility to Allergic Asthma in Azerbaijan Population of Iran: A Case-control Study.
Asthma
Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms.
Asthma
Neutralization of ADAM8 ameliorates liver injury and accelerates liver repair in carbon tetrachloride-induced acute liver injury.
Asthma
Overexpression of soluble ADAM33 promotes a hypercontractile phenotype of the airway smooth muscle cell in rat.
Asthma
Phylogenetic and molecular evolution of the ADAM (A Disintegrin And Metalloprotease) gene family from Xenopus tropicalis, to Mus musculus, Rattus norvegicus, and Homo sapiens.
Asthma
Polymorphisms in ADAM33 are associated with allergic rhinitis due to Japanese cedar pollen.
Asthma
Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study.
Asthma
Silencing a disintegrin and metalloproteinase?33 attenuates the proliferation of vascular smooth muscle cells via PI3K/AKT pathway: Implications in the pathogenesis of airway vascular remodeling.
Asthma
Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life.
Asthma
T1 polymorphism in a disintegrin and metalloproteinase 33 (ADAM33) gene may contribute to the risk of childhood asthma in Asians.
Asthma
The ADAM33 S2 Polymorphism Is Associated with Susceptibility to Pediatric Asthma in the Chinese Han Population.
Asthma
The effects of Th2 cytokines on the expression of ADAM33 in allergen-induced chronic airway inflammation.
Asthma
The Methylation Patterns of a Disintegrin and Metalloproteinase 33 Gene (ADAM33) in Adult Asthma.
Asthma
The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations.
Asthma
The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma.
Asthma
Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities.
Asthma
Upregulation of a disintegrin and metalloproteinase-33 by VEGF in human airway smooth muscle cells: Implications for asthma.
Asthma
[Relationship between disintegrin and metalloproteinase gene polymorphism of bronchial asthma and its severity in Uygur population].
Astrocytoma
Thromboxane A(2) receptor-mediated epidermal growth factor receptor transactivation: Involvement of PKC-delta and PKC-varepsilon in the shedding of epidermal growth factor receptor ligands.
Atherosclerosis
A disintegrin and metalloproteases: Molecular scissors in angiogenesis, inflammation and atherosclerosis.
Atherosclerosis
A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection.
Atherosclerosis
ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology.
Atherosclerosis
Association Between Plasma ADAMTS-9 Levels and Severity of Coronary Artery Disease.
Atherosclerosis
Association of a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13 polymorphisms with severity of coronary stenosis in type 2 diabetes mellitus.
Atherosclerosis
Association of ADAMTS4 and ADAMTS9 levels with cardiovascular risk in patients with primary hyperparathyroidism.
Atherosclerosis
Association of serum a disintegrin and metalloproteinase with thrombospodin motif 4 levels with the presence and severity of coronary artery disease.
Atherosclerosis
Decreased IRS2 and TIMP3 expression in monocytes from offspring of type 2 diabetic patients is correlated with insulin resistance and increased intima-media thickness.
Atherosclerosis
Endothelial Cell-Derived Von Willebrand Factor, But Not Platelet-Derived, Promotes Atherosclerosis in Apolipoprotein E-Deficient Mice.
Atherosclerosis
Genetic variants rs1994016 and rs3825807 in ADAMTS7 affect its mRNA expression in atherosclerotic occlusive peripheral arterial disease.
Atherosclerosis
Mechanisms in the inhibition of neointimal hyperplasia with triflavin in a rat model of balloon angioplasty.
Atherosclerosis
Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding.
Atherosclerosis
Role of ADAMTS-1 in atherosclerosis: remodeling of carotid artery, immunohistochemistry, and proteolysis of versican.
Atherosclerosis
The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-? and requires Smads, p38 mitogen-activated protein kinase and c-Jun.
Atherosclerosis
The impact of parathyroidectomy on serum ADAMTS1, ADAMTS4 levels, insulin resistance, and subclinical cardiovascular disease in primary hyperparathyroidism.
Atherosclerosis
Upregulation of ADAMTS?7 and downregulation of COMP are associated with aortic aneurysm.
Atherosclerosis
[Association of ADAMTS-1 gene polymorphisms with ischemic stroke caused by large artery atherosclerosis].
Atypical Hemolytic Uremic Syndrome
Deficiency of complement factor H-related proteins and autoantibody-positive hemolytic uremic syndrome in an infant with combined partial deficiencies and autoantibodies to complement factor H and ADAMTS13.
Atypical Hemolytic Uremic Syndrome
Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report.
Atypical Hemolytic Uremic Syndrome
Obstetric Nephrology: AKI and Thrombotic Microangiopathies in Pregnancy.
Autoimmune Diseases
Untying the knot of thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome.
Azoospermia
ADAMTS1 and ADAMTS5 metalloproteases produced by Sertoli cells: a potential diagnostic marker in azoospermia.
Bacterial Infections
Oxidation of Met1606 in von Willebrand factor is a risk factor for thrombotic and septic complications in chronic renal failure.
Bone Resorption
Comparative analysis of gingival crevicular fluid a disintegrin and metalloproteinase 8 levels in health and periodontal disease: A clinic-biochemical study.
Bone Resorption
Peptidomimetic antagonists of alphavbeta3 inhibit bone resorption by inhibiting osteoclast bone resorptive activity, not osteoclast adhesion to bone.
Bone Resorption
Role of alpha(v)beta(3) integrin in osteoclast migration and formation of the sealing zone.
Bone Resorption
Tablysin-15 inhibits osteoclastogenesis and LPS-induced bone loss via attenuating the integrin ?v?3 pathway.
Bone Resorption
The Novel p38 Inhibitor, Pamapimod, Inhibits Osteoclastogenesis and Counteracts Estrogen-Dependent Bone Loss in Mice.
Border Disease
Increased expressions of ADAMTS-13, neuronal nitric oxide synthase, and neurofilament correlate with severity of neuropathology in Border disease virus-infected small ruminants.
Brain Injuries, Traumatic
Relative Deficiency of Plasma A Disintegrin and Metalloprotease with Thrombospondin Type 1 Repeats 13 Activity and Elevation of Human Neutrophil Peptides in Patients with Traumatic Brain Injury.
Brain Neoplasms
From putative brain tumor marker to high cognitive abilities: Emerging roles of a disintegrin and metalloprotease (ADAM) 12 in the brain.
Breast Neoplasms
A disintegrin and metalloprotease 23 hypermethylation predicts decreased disease-free survival in low-risk breast cancer patients.
Breast Neoplasms
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease.
Breast Neoplasms
ADAM28 is expressed by epithelial cells in human normal tissues And protects from C1q-induced cell death.
Breast Neoplasms
ADAMTS1-mediated targeting of TSP-1 by PPAR? suppresses migration and invasion of breast cancer cells.
Breast Neoplasms
ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma.
Breast Neoplasms
Antitumoral Potential of Lansbermin-I, a Novel Disintegrin from Porthidium lansbergii lansbergii Venom on Breast Cancer Cells.
Breast Neoplasms
Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine?disrupting chemicals.
Breast Neoplasms
Cell migration inhibition activity of a non-RGD disintegrin from Crotalus durissus collilineatus venom.
Breast Neoplasms
Contortrostatin, a dimeric disintegrin from Agkistrodon contortrix contortrix, inhibits breast cancer progression.
Breast Neoplasms
Endostatin and irradiation modifies the activity of ADAM10 and neprilysin in breast cancer cells.
Breast Neoplasms
How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study.
Breast Neoplasms
Inhibition of platelets and tumor cell adhesion by the disintegrin domain of human ADAM9 to collagen I under dynamic flow conditions.
Breast Neoplasms
Intravenous liposomal delivery of the snake venom disintegrin contortrostatin limits breast cancer progression.
Breast Neoplasms
Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.
Breast Neoplasms
Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells.
Breast Neoplasms
Src Plays a Key Role in ADAM28 Expression in v-src-Transformed Epithelial Cells and Human Carcinoma Cells.
Breast Neoplasms
Thalidomide combined with irradiation alters the activity of two proteases.
Breast Neoplasms
The anticancer properties and mechanism of action of tablysin-15, the RGD-containing disintegrin, in breast cancer cells.
Breast Neoplasms
The proteomic analysis of breast cell line exosomes reveals disease patterns and potential biomarkers.
Capsule Opacification
Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathway.
Carcinogenesis
ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration.
Carcinogenesis
ADAM-12 as a Diagnostic Marker for the Proliferation, Migration and Invasion in Patients with Small Cell Lung Cancer.
Carcinogenesis
ADAM8 expression in prostate cancer is associated with parameters of unfavorable prognosis.
Carcinogenesis
ADAM9 functions as a promoter of gastric cancer growth which is negatively and post-transcriptionally regulated by miR-126.
Carcinogenesis
Disintegrins from snake venoms and their applications in cancer research and therapy.
Carcinogenesis
Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer.
Carcinogenesis
Increased Expression of a Disintegrin and Metalloprotease-9 in Hepatocellular Carcinoma: Implications for Tumor Progression and Prognosis.
Carcinogenesis
miR-126 inhibits cell growth, invasion, and migration of osteosarcoma cells by downregulating ADAM-9.
Carcinogenesis
Molecular characterization and expression of a disintegrin and metalloproteinase with thrombospondin motifs 8 in chicken.
Carcinogenesis
Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer.
Carcinogenesis
Stroma-derived but not tumor ADAMTS1 is a main driver of tumor growth and metastasis.
Carcinogenesis
Transcript response of soft coral (Scleronephthya gracillimum) on exposure to polycyclic aromatic hydrocarbons.
Carcinogenesis
Upregulation of a disintegrin and metalloprotease 8 is associated with progression and prognosis of patients with gastric cancer.
Carcinoma
A disintegrin and metalloproteinase 17 mRNA and protein expression in esophageal squamous cell carcinoma, as well as its clinicopathological factors and prognosis.
Carcinoma
A novel snake venom disintegrin that inhibits human ovarian cancer dissemination and angiogenesis in an orthotopic nude mouse model.
Carcinoma
A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions.
Carcinoma
ADAM10 expression in gastric adenocarcinoma: Results of a curative gastrectomy cohort.
Carcinoma
ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression.
Carcinoma
ADAM28 is expressed by epithelial cells in human normal tissues And protects from C1q-induced cell death.
Carcinoma
ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type, and Acts as a Prognostic Factor in Lower-Grade Gliomas.
Carcinoma
ADAM9 is highly expressed in renal cell cancer and is associated with tumour progression.
Carcinoma
Anti-invasive and anti-adhesive activities of a recombinant disintegrin, r-viridistatin 2, derived from the Prairie rattlesnake (Crotalus viridis viridis).
Carcinoma
Differential expression of degradome components in cutaneous squamous cell carcinomas.
Carcinoma
Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor.
Carcinoma
Expression and clinical significance of ADAM17 protein in esophageal squamous cell carcinoma.
Carcinoma
Expression of "a disintegrin and metalloproteinase-33" (ADAM-33) protein in laryngeal squamous cell carcinoma.
Carcinoma
Expression of a disintegrin and metalloprotease (ADAM and ADAMTS) enzymes in human non-small-cell lung carcinomas (NSCLC).
Carcinoma
Expression of ADAM29 and FAM135B in the pathological evolution from normal esophageal epithelium to esophageal cancer: Their differences and clinical significance.
Carcinoma
Involvement of NF-kappaB-mediated maturation of ADAM-17 in the invasion of oral squamous cell carcinoma.
Carcinoma
Overexpression of A disintegrin and metalloprotease 10 promotes tumor proliferation, migration and poor prognosis in hypopharyngeal squamous cell carcinoma.
Carcinoma
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.
Carcinoma
Selective inhibition of ADAM28 suppresses lung carcinoma cell growth and metastasis.
Carcinoma
SOX4, an epithelial-mesenchymal transition inducer, transactivates ADAM28 gene expression and co-localizes with ADAM28 at the invasive front of human breast and lung carcinomas.
Carcinoma
Src Plays a Key Role in ADAM28 Expression in v-src-Transformed Epithelial Cells and Human Carcinoma Cells.
Carcinoma
The disintegrin domain of ADAM17 antagonises fibroblast?carcinoma cell interactions.
Carcinoma
The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer.
Carcinoma, Ductal
Relationship Between ADAMTS8, ADAMTS18, and ADAMTS20 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) Expressions and Tumor Molecular Classification, Clinical Pathological Parameters, and Prognosis in Breast Invasive Ductal Carcinoma.
Carcinoma, Embryonal
Role of multiple beta1 integrins in cell adhesion to the disintegrin domains of ADAMs 2 and 3.
Carcinoma, Hepatocellular
A disintegrin and metalloprotease (ADAM)10 is highly expressed in hepatocellular carcinoma and is associated with tumour progression.
Carcinoma, Hepatocellular
A Disintegrin and Metalloproteinase 9 (ADAM9) in Advanced Hepatocellular Carcinoma and Their Role as a Biomarker During Hepatocellular Carcinoma Immunotherapy.
Carcinoma, Hepatocellular
Angiotensin II and epidermal growth factor receptor cross-talk mediated by a disintegrin and metalloprotease accelerates tumor cell proliferation of hepatocellular carcinoma cell lines.
Carcinoma, Hepatocellular
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells.
Carcinoma, Hepatocellular
Increased Expression of a Disintegrin and Metalloprotease-9 in Hepatocellular Carcinoma: Implications for Tumor Progression and Prognosis.
Carcinoma, Hepatocellular
microRNA-1274a, a modulator of sorafenib induced a disintegrin and metalloproteinase 9 (ADAM9) down-regulation in hepatocellular carcinoma.
Carcinoma, Hepatocellular
miR-203 suppresses the proliferation and metastasis of hepatocellular carcinoma by targeting oncogene ADAM9 and oncogenic long non-coding RNA HULC.
Carcinoma, Hepatocellular
Overexpression of a disintegrin and metalloproteinase 21 is associated with motility, metastasis, and poor prognosis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Overexpression of ADAM9 decreases radiosensitivity of hepatocellular carcinoma cell by activating autophagy.
Carcinoma, Hepatocellular
Polymorphisms of a Disintegrin and Metalloproteinase with Thrombospondin Motifs 5 and Aflatoxin B1-Related Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Single-nucleotide polymorphisms in the coding region of a disintegrin and metalloproteinase with thrombospondin motifs 4 and hepatocellular carcinoma: A retrospective case-control study.
Carcinoma, Hepatocellular
Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9.
Carcinoma, Hepatocellular
The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice.
Carcinoma, Non-Small-Cell Lung
Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factor.
Carcinoma, Non-Small-Cell Lung
Combined RNAi targeting human Stat3 and ADAM9 as gene therapy for non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Expression of a disintegrin and metalloprotease (ADAM and ADAMTS) enzymes in human non-small-cell lung carcinomas (NSCLC).
Carcinoma, Non-Small-Cell Lung
HDGF and ADAM9 are novel molecular staging biomarkers, prognostic biomarkers and predictive biomarkers for adjuvant chemotherapy in surgically resected stage I non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
High expression of a disintegrin and metalloproteinase-9 predicts a shortened survival time in completely resected stage I non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
[Expression and clinical significance of a disintegrin and metalloprotease 8 (ADAM8) and epidermal growth factor receptor (EGFR) in non-small cell lung cancer]
Carcinoma, Renal Cell
ADAM9 is highly expressed in renal cell cancer and is associated with tumour progression.
Carcinoma, Squamous Cell
Differential expression of degradome components in cutaneous squamous cell carcinomas.
Carcinoma, Squamous Cell
Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.
Cardiomegaly
A disintegrin and metalloproteinase 12 prevents heart failure by regulating cardiac hypertrophy and fibrosis.
Cardiomegaly
Critical Role of ADAMTS2 (A Disintegrin and Metalloproteinase With Thrombospondin Motifs 2) in Cardiac Hypertrophy Induced by Pressure Overload.
Cardiomegaly
Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy.
Cardiomegaly
Upregulation of Nox4 Promotes Angiotensin II-Induced Epidermal Growth Factor Receptor Activation and Subsequent Cardiac Hypertrophy by Increasing ADAM17 Expression.
Cardiomyopathies
[Improvement and the mechanism of cardiac function by knockdown of ADAM10 in adriamycin-induced cardiomyopathy rats].
Cardiomyopathy, Dilated
Altered expression of disintegrin metalloproteinases and their inhibitor in human dilated cardiomyopathy.
Cardiomyopathy, Dilated
Inhibition of ADAM10 ameliorates doxorubicin-induced cardiac remodeling by suppressing N-cadherin cleavage.
Cardiomyopathy, Dilated
Role of blocking ADAM10 hydrolysis site on N-cadherin by single-chain antibody in ventricular remodeling.
Cardiovascular Diseases
ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease.
Cardiovascular Diseases
Clinical and prognostic significance of serum levels of von Willebrand factor and ADAMTS-13 antigens in AL amyloidosis.
Cardiovascular Diseases
Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones.
Cardiovascular Diseases
The role of ADAMTS4 and ADAMTS9 in cardiovascular disease in premature ovarian insufficiency and idiopathic hypogonadotropic hypogonadism.
Cholangiocarcinoma
Cholangiocarcinoma presenting with acquired thrombotic thrombocytopenic purpura confirmed by positive autoantibodies of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13.
Cholangiocarcinoma
Comparison of ADAM19 and CUEDC2 expressions in EHCC and their clinicopathological significances.
Cholesteatoma
Expression of disintegrin and metalloproteinase family proteins 10, 12 and 17 in cholesteatoma.
Chondroma
Overexpression of A disintegrin and metalloproteinase 28 is correlated with high histologic grade in conventional chondrosarcoma.
Chondrosarcoma
ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.
Chondrosarcoma
Correlation between the histological grade of chondrosarcoma and the expression of MMPs, ADAMTSs and TIMPs.
Chondrosarcoma
Overexpression of A disintegrin and metalloproteinase 28 is correlated with high histologic grade in conventional chondrosarcoma.
Chronic Periodontitis
Inducible expression of A Disintegrin and Metalloproteinase 8 in chronic periodontitis and gingival epithelial cells.
Chronic Periodontitis
Reduced ADAM8 levels upon non-surgical periodontal therapy in patients with chronic periodontitis.
Colitis, Ischemic
Human colonic myocytes are involved in postischemic inflammation through ADAM17-dependent TNFalpha production.
Colitis, Ulcerative
In situ evidence of involvement of Schwann cells in ulcerative colitis: autocrine and paracrine signaling by A disintegrin and metalloprotease-17-mediated tumor necrosis factor alpha production.
Colonic Neoplasms
A disintegrin and metalloproteinase 8 induced epithelial-mesenchymal transition to promote the invasion of colon cancer cells via TGF-?/Smad2/3 signalling pathway.
Colonic Neoplasms
A metalloproteinase of the disintegrin and metalloproteinases and the ThromboSpondin Motifs 6 as a novel marker for colon cancer: functional experiments.
Colonic Neoplasms
Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression.
Colonic Neoplasms
Overexpression of ADAM9 enhances growth factor-mediated recycling of E-cadherin in human colon cancer cell line HT29 cells.
Colorectal Neoplasms
A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling.
Colorectal Neoplasms
Epigenetic Regulation of a Disintegrin and Metalloproteinase (ADAM) Transcription in Colorectal Cancer Cells: Involvement of ?-Catenin, BRG1, and KDM4.
Colorectal Neoplasms
Epigenetic silencing of ADAMTS5 is associated with increased invasiveness and poor survival in patients with colorectal cancer.
Colorectal Neoplasms
Expression and Function of a Disintegrin and Metalloproteinases in Cancer-Associated Fibroblasts of Colorectal Cancer.
Colorectal Neoplasms
Expression of A disintegrin and metalloprotease 8 is associated with cell growth and poor survival in colorectal cancer.
Colorectal Neoplasms
Heterogeneity of metalloproteinase expression in colorectal cancer - relation of molecular findings to basic morphology.
Colorectal Neoplasms
MicroRNA-552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28.
Colorectal Neoplasms
Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency.
Communicable Diseases
A Disintegrin and Metalloproteinase-Control Elements in Infectious Diseases.
Cone-Rod Dystrophies
An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9.
Connective Tissue Diseases
Hypertensive emergency presenting with diffuse alveolar hemorrhaging and thrombotic microangiopathy: A case report and review of the literature.
Coronary Artery Disease
ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1.
Coronary Artery Disease
ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis.
Coronary Artery Disease
Association between plasma ADAMTS-7 levels and severity of disease in patients with stable obstructive coronary artery disease.
Coronary Artery Disease
Association of serum a disintegrin and metalloproteinase with thrombospodin motif 4 levels with the presence and severity of coronary artery disease.
Coronary Artery Disease
Protective effect of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 haplotype on coronary artery disease.
Coronary Stenosis
Association of a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13 polymorphisms with severity of coronary stenosis in type 2 diabetes mellitus.
Demyelinating Diseases
Cornel Iridoid Glycoside Ameliorated Alzheimer's Disease-Like Pathologies and Necroptosis through RIPK1/MLKL Pathway in Young and Aged SAMP8 Mice.
Diabetes Mellitus
Association between Von Willebrand factor, disintegrin and metalloproteinase with thrombospondin type 1 motif member 13, d-Dimer and cystatin C levels with retinopathy in type 1 diabetes mellitus.
Diabetes Mellitus
Association of a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13 polymorphisms with severity of coronary stenosis in type 2 diabetes mellitus.
Diabetes Mellitus, Type 1
Association between Von Willebrand factor, disintegrin and metalloproteinase with thrombospondin type 1 motif member 13, d-Dimer and cystatin C levels with retinopathy in type 1 diabetes mellitus.
Diabetes Mellitus, Type 1
Von Willebrand Factor, ADAMTS13 and D-Dimer Are Correlated with Different Levels of Nephropathy in Type 1 Diabetes Mellitus.
Diabetes Mellitus, Type 2
Association of a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13 polymorphisms with severity of coronary stenosis in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Decreased IRS2 and TIMP3 expression in monocytes from offspring of type 2 diabetic patients is correlated with insulin resistance and increased intima-media thickness.
Diabetes Mellitus, Type 2
The Metalloproteinase ADAM28 Promotes Metabolic Dysfunction in Mice.
Diabetes, Gestational
Evaluation of second trimester amniotic fluid ADAMTS4, ADAMTS5, interleukin-6 and tumor necrosis factor-? levels in patients with gestational diabetes mellitus.
Diabetic Nephropathies
Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report.
Diabetic Retinopathy
Metalloproteinases mediate diabetes-induced retinal neuropathy and vasculopathy.
Digestive System Neoplasms
Novel role of microRNA-126 in digestive system cancers: From bench to bedside.
Disseminated Intravascular Coagulation
Disseminated intravascular coagulation caused by moojenactivase, a procoagulant snake venom metalloprotease.
Disseminated Intravascular Coagulation
The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulation.
Down Syndrome
Comparative localization of ADAMs 10 and 15 in human cerebral cortex normal aging, Alzheimer disease and Down syndrome.
Down Syndrome
Maternal serum ADAM12 (A disintegrin and metalloprotease) in chromosomally abnormal pregnancy at 11-13 weeks.
Down Syndrome
Maternal serum ADAM12s as a potential marker of trisomy 21 prior to 10 weeks of gestation.
Drug Hypersensitivity Syndrome
DRESS syndrome and thrombotic thrombocytopaenic purpura: are they related?
Dupuytren Contracture
Metalloproteinase gene expression correlates with clinical outcome in Dupuytren's disease.
Encephalomyelitis
The disintegrin domain of ADAM 8 enhances protection against rat experimental autoimmune encephalomyelitis, neuritis and uveitis by a polyvalent autoantigen vaccine.
Encephalomyelitis, Autoimmune, Experimental
The disintegrin domain of ADAM 8 enhances protection against rat experimental autoimmune encephalomyelitis, neuritis and uveitis by a polyvalent autoantigen vaccine.
Encephalomyelitis, Autoimmune, Experimental
Treatment of an encephalitogenic peptide from guinea pig myelin basic protein with alpha-protease and thermolysin. Isolation of fragments and determination of cleavage sites.
Endometrial Neoplasms
Combined therapy with disintegrin and melphalan as a new strategy in inhibition of endometrial cancer cell line (Ishikawa) growth.
Endometrial Neoplasms
Long non-coding RNA (lncRNA) HOXB-AS3 promotes cell proliferation and inhibits apoptosis by regulating ADAM9 expression through targeting miR-498-5p in endometrial carcinoma.
Endometrial Neoplasms
The investigation of serum levels of ADAMTS 5 and 8 (the A disintegrin and metalloproteinase with thrombospondin motifs) in the etiology of endometrial cancer.
Endometriosis
Dysregulation of the ADAM17/Notch signalling pathways in endometriosis: from oxidative stress to fibrosis.
Endotoxemia
Improvements in endotoxemic syndromes using a disintegrin, rhodostomin, through integrin ?v?3-dependent pathway.
Endotoxemia
Snake Venom Disintegrin Inhibits the Activation of Toll-Like Receptors and Alleviates Sepsis through Integrin alphaVbeta3 Blockade.
Esophageal Neoplasms
Methylation status of ADAM12 promoter are associated with its expression levels in colorectal cancer.
Esophageal Squamous Cell Carcinoma
A disintegrin and metalloproteinase 17 mRNA and protein expression in esophageal squamous cell carcinoma, as well as its clinicopathological factors and prognosis.
Esophageal Squamous Cell Carcinoma
Expression and clinical significance of ADAM17 protein in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Expression of ADAM29 and FAM135B in the pathological evolution from normal esophageal epithelium to esophageal cancer: Their differences and clinical significance.
Eye Diseases
Metalloproteinases mediate diabetes-induced retinal neuropathy and vasculopathy.
Fibrosarcoma
Anti-invasive and anti-adhesive activities of a recombinant disintegrin, r-viridistatin 2, derived from the Prairie rattlesnake (Crotalus viridis viridis).
Gastroesophageal Reflux
Disintegrin and metalloproteinases (ADAMs) expression in gastroesophageal reflux disease and in esophageal adenocarcinoma.
Gastroesophageal Reflux
Role of E-cadherin in the Pathogenesis of Gastroesophageal Reflux Disease.
Gestational Trophoblastic Disease
Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases.
Giant Cell Tumors
The expression of ADAM12 (meltrin alpha) in human giant cell tumours of bone.
Gingivitis
Reduced ADAM8 levels upon non-surgical periodontal therapy in patients with chronic periodontitis.
Glioblastoma
A disintegrin and metalloproteinases 10 and 17 modulate the immunogenicity of glioblastoma-initiating cells.
Glioblastoma
Functional effect of contortrostatin, a snake venom disintegrin, on human glioma cell invasion in vitro.
Glioblastoma
Investigation of Vipera Anatolica Venom Disintegrin via Intracellular Uptake with Radiolabeling Study and Cell-Based Electrochemical Biosensing Assay.
Glioblastoma
Mass spectrometry guided venom profiling and bioactivity screening of the Anatolian Meadow Viper, Vipera anatolica.
Glioblastoma
Matrix-degrading proteases ADAMTS4 and ADAMTS5 (disintegrins and metalloproteinases with thrombospondin motifs 4 and 5) are expressed in human glioblastomas.
Glioblastoma
MiR-145 inhibits the epithelial-to-mesenchymal transition via targeting ADAM19 in human glioblastoma.
Glioblastoma
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.
Glioma
ADAM22, expressed in normal brain but not in high-grade gliomas, inhibits cellular proliferation via the disintegrin domain.
Glioma
Anti-invasive effect of contortrostatin, a snake venom disintegrin, and TNF-alpha on malignant glioma cells.
Glioma
Brain-enriched hyaluronan binding (BEHAB)/brevican cleavage in a glioma cell line is mediated by a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family member.
Glioma
Functional effect of contortrostatin, a snake venom disintegrin, on human glioma cell invasion in vitro.
Glioma
Malpigmentation of Common Sole (Solea solea) during Metamorphosis Is Associated with Differential Synaptic-Related Gene Expression.
Glioma
NKG2D- and T-cell receptor-dependent lysis of malignant glioma cell lines by human ?? T cells: Modulation by temozolomide and A disintegrin and metalloproteases 10 and 17 inhibitors.
Glioma
Overexpression of a disintegrin and metalloprotease 8 in human gliomas is implicated in tumor progression and prognosis.
Glioma
Potent mimicry of fibronectin-induced intracellular signaling in glioma cells by the homodimeric snake venom disintegrin contortrostatin.
Glioma
Regulatory effect of nerve growth factor in alpha9beta1 integrin-dependent progression of glioblastoma.
Glioma
Regulatory effect of nerve growth factor in {alpha}9{beta}1 integrin-dependent progression of glioblastoma.
Glioma
The role of contortrostatin, a snake venom disintegrin, in the inhibition of tumor progression and prolongation of survival in a rodent glioma model.
Glioma
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Head and Neck Neoplasms
A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.
Heart Arrest
Thrombotic Thrombocytopenic Purpura: Revisiting a Miss and an Inevitable Consequence.
Heart Diseases
Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans.
Heart Diseases
Insights into the activity, differential expression, mutual regulation, and functions of matrix metalloproteinases and a disintegrin and metalloproteinases in hypertension and cardiac disease.
Heart Diseases
Interrelation between Expression of ADAM 10 and MMP 9 and Synthesis of Peroxynitrite in Doxorubicin Induced Cardiomyopathy.
Heart Failure
Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding.
Heart Septal Defects, Ventricular
Essential role for ADAM19 in cardiovascular morphogenesis.
Hemolytic-Uremic Syndrome
Acute kidney injury in Hemiscorpius lepturus scorpion stung children: Risk factors and clinical features.
Hemolytic-Uremic Syndrome
Diagnostic relevance of ADAMTS13 activity: evaluation of 28 patients with thrombotic thrombocytopenic purpura - hemolytic uremic syndrome clinical diagnosis.
Hemolytic-Uremic Syndrome
Natural history of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.
Hemolytic-Uremic Syndrome
Obstetric Nephrology: AKI and Thrombotic Microangiopathies in Pregnancy.
Hepatitis B, Chronic
Plasma Level of ADAMTS13 or IL-12 as an Indicator of HBeAg Seroconversion in Chronic Hepatitis B Patients Undergoing m-ETV Treatment.
Hepatitis C
ADAMTS13 Levels in Young Patients With ?-Thalassemia Major: Relation to Hepatitis C Virus Infection, Liver Cirrhosis, and Iron Overload.
Hepatitis C, Chronic
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Herpes Simplex
Contortrostatin, a homodimeric disintegrin isolated from snake venom inhibits herpes simplex virus entry and cell fusion.
Herpes Zoster
GPI-Anchored Protein Complex, LY6K/TEX101, Is Required for Sperm Migration into the Oviduct and Male Fertility in Mice.
Herpes Zoster
Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) beta.
Herpes Zoster
Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male infertility.
Hodgkin Disease
Inhibitors of A Disintegrin And Metalloproteinases-10 reduce Hodgkin lymphoma cell growth in 3D microenvironments and enhance brentuximab-vedotin effect.
Huntington Disease
ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.
Hydatidiform Mole
Maternal serum disintegrin and metalloprotease protein-12 in early pregnancy as a potential marker of adverse pregnancy outcomes.
Hyperlipidemias
CD11c+ macrophages and levels of TNF-? and MMP-3 are increased in synovial and adipose tissues of osteoarthritic mice with hyperlipidemia.
Hyperlipidemias
Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study.
Hypersensitivity
ADAM8 substrate specificity: Influence of pH on pre-processing and proteoglycan degradation.
Hypersensitivity
Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy.
Hypertension
?-Lipoic acid reduces neurogenic hypertension by blunting oxidative stress-mediated increase in ADAM17.
Hypertension
Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy.
Hypertension
Insights into the activity, differential expression, mutual regulation, and functions of matrix metalloproteinases and a disintegrin and metalloproteinases in hypertension and cardiac disease.
Hypertension
Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage.
Hypertension
Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy.
Hypertension, Malignant
Thrombotic microangiopathy due to malignant hypertension complicated with late-onset bleeding after renal biopsy.
Hypertension, Portal
ADAMTS13 deficiency, despite well-compensated liver functions in patients with noncirrhotic portal hypertension.
Hypertension, Portal
Altered von Willebrand Factor and ADAMTS13 Levels in Children With Cirrhosis and Extrahepatic Portal Hypertension.
Hypoglossal Nerve Injuries
A disintegrin and metalloprotease with thrombospondin type1 motifs (ADAMTS-1) and IL-1 receptor type 1 mRNAs are simultaneously induced in nerve injured motor neurons.
Hypogonadism
The role of ADAMTS4 and ADAMTS9 in cardiovascular disease in premature ovarian insufficiency and idiopathic hypogonadotropic hypogonadism.
Immune System Diseases
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
Infarction, Middle Cerebral Artery
Crotalus atrox disintegrin reduces hemorrhagic transformation by attenuating matrix metalloproteinase-9 activity after middle cerebral artery occlusion in hyperglycemic male rats.
Infarction, Middle Cerebral Artery
Evaluation of the disintegrin, triflavin, in a rat middle cerebral artery thrombosis model.
Infections
ADAMTS13 Levels in Young Patients With ?-Thalassemia Major: Relation to Hepatitis C Virus Infection, Liver Cirrhosis, and Iron Overload.
Infections
Cronobacter sakazakii Infection in Early Postnatal Rats Impaired Contextual-Associated Learning: a Putative Role of C5a-Mediated NF-?? and ASK1 Pathways.
Infections
Dissecting the role of ADAM10 as a mediator of Staphylococcus aureus ?-toxin action.
Infections
Expression levels of A disintegrin and metalloproteases (ADAMs), and Th17-related cytokines and their association with Helicobacter pylori infection in patients with gastroduodenal diseases.
Infections
von Willebrand factor increases in experimental cerebral malaria but is not essential for late-stage pathogenesis in mice.
Inflammatory Bowel Diseases
High Expression of the "A Disintegrin And Metalloprotease" 19 (ADAM19), a Sheddase for TNF-? in the Mucosa of Patients with Inflammatory Bowel Diseases.
Inflammatory Bowel Diseases
Infliximab restores the dysfunctional matrix remodeling protein and growth factor gene expression in patients with inflammatory bowel disease.
Inflammatory Bowel Diseases
Molecular design and structural optimization of potent peptide hydroxamate inhibitors to selectively target human ADAM metallopeptidase domain 17.
Influenza, Human
ADAM10 Partially Protects Mice against Influenza Pneumonia by Suppressing Specific Myeloid Cell Population.
Insulin Resistance
TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1.
Intervertebral Disc Degeneration
Resistin Promotes Intervertebral Disc Degeneration by Up-Regulation of ADAMTS-5 Through p38 MAPK Signaling Pathway.
Intervertebral Disc Degeneration
[Electroacupuncture down-regulates expression of ADAMTS-4 of intervertebral disc in rats with lumbar intervertebral disc degeneration].
Intervertebral Disc Degeneration
[Expression of p16INK4a in nucleus pulposus and its effect on degenerated intervertebral discs].
Intestinal Volvulus
Human colonic myocytes are involved in postischemic inflammation through ADAM17-dependent TNFalpha production.
Iron Overload
ADAMTS13 Levels in Young Patients With ?-Thalassemia Major: Relation to Hepatitis C Virus Infection, Liver Cirrhosis, and Iron Overload.
Ischemic Stroke
ADAMTS-13 Activity Predicts Outcome in Acute Ischaemic Stroke Patients Undergoing Endovascular Treatment.
Ischemic Stroke
Association between ADAM17 Promoter Polymorphisms and Ischemic Stroke in a Chinese Population.
Ischemic Stroke
Congenital thrombotic thrombocytopenic purpura presenting in adulthood with recurrent cerebrovascular events.
Ischemic Stroke
The Value of ADAMTS13 in Predicting Clinical Outcomes in Patients With Acute Ischemic Stroke Receiving Thrombolysis.
Ischemic Stroke
[Association of ADAMTS-1 gene polymorphisms with ischemic stroke caused by large artery atherosclerosis].
Joint Diseases
Detection of ADAMTS-4 activity using a fluorogenic peptide-conjugated Au nanoparticle probe in human knee synovial fluid.
Joint Diseases
Fluorescence resonance energy transfer assay for high-throughput screening of ADAMTS1 inhibitors.
Joint Diseases
Nesfatin-1 suppresses interleukin-1?-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats.
Joint Diseases
Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis.
Kidney Diseases
ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury.
Kidney Failure, Chronic
Predictive value of ADAMTS-13 on concealed chronic renal failure in COPD patients.
Leukemia
Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci.
Leukemia
Integrin VLA-5 and FAK are Good Targets to Improve Treatment Response in the Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia.
Leukemia, Hairy Cell
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Liver Cirrhosis
ADAMTS13 Levels in Young Patients With ?-Thalassemia Major: Relation to Hepatitis C Virus Infection, Liver Cirrhosis, and Iron Overload.
Liver Cirrhosis
Increased ADAMTS-13 proteolytic activity in rat hepatic stellate cells upon activation in vitro and in vivo.
Liver Diseases
Hepatic expression of A disintegrin and metalloproteinase (ADAM) and ADAMs with thrombospondin motives (ADAM-TS) enzymes in patients with chronic liver diseases.
Liver Diseases
Targeting von Willebrand factor in liver diseases: A novel therapeutic strategy?
Liver Diseases
Three Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.
Liver Neoplasms
Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells.
Liver Neoplasms
MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma.
Liver Neoplasms
Transcriptome analysis of PPAR? target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion.
Lung Diseases
Association between F+1 polymorphism in a disintegrin and metalloprotease 33 (ADAM33) gene and chronic obstructive pulmonary disease susceptibility: An evidence-based meta-analysis.
Lung Diseases
Polymorphisms of the ADAM33 gene and Chronic Obstructive Pulmonary Disease Risk: a Meta-Analysis.
Lung Neoplasms
ADAM28 is a serological and histochemical marker for non-small-cell lung cancers.
Lung Neoplasms
ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT.
Lung Neoplasms
Association of ABO blood groups with von Willebrand factor, factor VIII and ADAMTS-13 in patients with lung cancer.
Lung Neoplasms
Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factor.
Lung Neoplasms
Combined RNAi targeting human Stat3 and ADAM9 as gene therapy for non-small cell lung cancer.
Lung Neoplasms
Differential expressions of matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs and their endogenous inhibitors among histologic subtypes of lung cancers.
Lung Neoplasms
Differential Expressions Of Matrix Metalloproteinases, A Disintegrin And Metalloproteinases, And A Disintegrin And Metalloproteinases With Thrombospondin Motifs And Their Endogenous Inhibitors Among Histologic Subtypes Of Lung Cancers.
Lung Neoplasms
Effect of tetramethylpyrazine combined with cisplatin on VEGF, KLF4 and ADAMTS1 in Lewis lung cancer mice.
Lung Neoplasms
HDGF and ADAM9 are novel molecular staging biomarkers, prognostic biomarkers and predictive biomarkers for adjuvant chemotherapy in surgically resected stage I non-small cell lung cancer.
Lung Neoplasms
High expression of a disintegrin and metalloproteinase-9 predicts a shortened survival time in completely resected stage I non-small cell lung cancer.
Lung Neoplasms
Lung cancer-derived galectin-1 enhances tumorigenic potentiation of tumor associated dendritic cells by expressing HB-EGF.
Lung Neoplasms
Protective effects of ADAM8 against cisplatin-mediated apoptosis in non-small-cell lung cancer.
Lung Neoplasms
RNAi-mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non-small lung cancer in vitro and in vivo.
Lung Neoplasms
Saxatilin suppresses tumor-induced angiogenesis by regulating VEGF expression in NCI-H460 human lung cancer cells.
Lung Neoplasms
The disintegrin tzabcanin inhibits adhesion and migration in melanoma and lung cancer cells.
Lung Neoplasms
The metalloproteinase ADAM-12 regulates bronchial epithelial cell proliferation and apoptosis.
Lung Neoplasms
[Expression and clinical significance of a disintegrin and metalloprotease 8 (ADAM8) and epidermal growth factor receptor (EGFR) in non-small cell lung cancer]
Lymphatic Metastasis
ADAM28 is a serological and histochemical marker for non-small-cell lung cancers.
Lymphatic Metastasis
Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factor.
Lymphoma
Evaluation of Anti-inflammatory and Regenerative Efficiency of Naringin and Naringenin in Degenerated Human Nucleus Pulposus Cells: Biological and Molecular Modeling Studies.
Lymphoma, B-Cell
Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection.
Lymphoma, B-Cell
Hydrostatic Pressure Regulates Oxidative Stress through microRNA in Human Osteoarthritic Chondrocytes.
Malaria
Effect of metalloprotease inhibitors on invasion of red blood cell by Plasmodium falciparum.
Medulloblastoma
Prognostic and clinical implication of a disintegrin and metalloprotease 8 expression in pediatric medulloblastoma.
Melanoma
A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis.
Melanoma
Angiostatic activity of obtustatin as alpha1beta1 integrin inhibitor in experimental melanoma growth.
Melanoma
Anti-invasive and anti-adhesive activities of a recombinant disintegrin, r-viridistatin 2, derived from the Prairie rattlesnake (Crotalus viridis viridis).
Melanoma
Application of topologically constrained mini-proteins as ligands, substrates, and inhibitors.
Melanoma
Biological Properties of Melanoma and Endothelial Cells after Plasmid AMEP Gene Electrotransfer Depend on Integrin Quantity on Cells.
Melanoma
Contortrostatin, a snake venom disintegrin, inhibits beta 1 integrin-mediated human metastatic melanoma cell adhesion and blocks experimental metastasis.
Melanoma
Disintegrin tablysin-15 suppresses cancer hallmarks in melanoma cells by blocking FAK/Akt/ERK and NF-?B signaling.
Melanoma
Echistatin induces decrease of pp125FAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells.
Melanoma
Effect of the disintegrin eristostatin on melanoma-natural killer cell interactions.
Melanoma
Identification of binding peptides of the ADAM15 disintegrin domain using phage display.
Melanoma
Inhibitory effect of salmosin, a Korean snake venom-derived disintegrin, on the integrin alphav-mediated proliferation of SK-Mel-2 human melanoma cells.
Melanoma
New insights on disintegrin-receptor interactions: eristostatin and melanoma cells.
Melanoma
Recombinant rubistatin (r-Rub), an MVD disintegrin, inhibits cell migration and proliferation, and is a strong apoptotic inducer of the human melanoma cell line SK-Mel-28.
Melanoma
Rhodostomin, a snake venom disintegrin, inhibits angiogenesis elicited by basic fibroblast growth factor and suppresses tumor growth by a selective alpha(v)beta(3) blockade of endothelial cells.
Melanoma
Role of multiple beta1 integrins in cell adhesion to the disintegrin domains of ADAMs 2 and 3.
Melanoma
Screening cellular proteins involved in the anti-proliferative effect of the ADAM15 disintegrin domain in murine melanoma cells.
Melanoma
The disintegrin eristostatin interferes with integrin alpha 4 beta 1 function and with experimental metastasis of human melanoma cells.
Melanoma
The disintegrin tzabcanin inhibits adhesion and migration in melanoma and lung cancer cells.
Melanoma
UV-induced EGFR signal transactivation is dependent on proligand shedding by activated metalloproteases in skin cancer cell lines.
Melanoma, Experimental
Antitumoral and antimetastatic effect of antiangiogenic plasmids in B16 melanoma: Higher efficiency of the recombinant disintegrin domain of ADAM 15.
Melanoma, Experimental
Suppressive mechanism of salmosin, a novel disintegrin in B16 melanoma cell metastasis.
Metabolic Syndrome
A Disintegrin and Metalloproteinase with Thrombospondin Motifs 18 Deficiency Leads to Visceral Adiposity and Associated Metabolic Syndrome in Mice.
Mouth Neoplasms
A disintegrin and metalloproteinase domain 17-epidermal growth factor receptor signaling contributes to oral cancer pain.
Mouth Neoplasms
Involvement of the A disintegrin and metalloproteinase 9 in oral cancer cell invasion.
Multiple Myeloma
Activation of the P2X7 receptor induces the rapid shedding of CD23 from human and murine B cells.
Multiple Sclerosis
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Muscular Dystrophies
Animal models for muscular dystrophy; mechanism of disease and potential therapy.
Muscular Dystrophy, Duchenne
Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins.
Myocardial Infarction
Effect of Acute Myocardial Infarction on a Disintegrin and Metalloprotease with Thrombospondin Motif 13 and Von Willebrand Factor and Their Relationship with Markers of Inflammation.
Myocardial Infarction
Effects of metoprolol treatment on a disintegrin metalloproteinase expression and extracellular matrix remodeling after myocardial infarction in rats.
Myocardial Infarction
Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack.
Myocardial Infarction
Molecular Imaging of VWF (von Willebrand Factor) and Platelet Adhesion in Postischemic Impaired Microvascular Reflow.
Myocardial Infarction
Myocardial infarction induces early increased remote ADAM8 expression of rat hearts after cardiac arrest.
Myocardial Infarction
Syzygium Polyanthum Reduced TNF-? and ADAM17 Protein Expression in Myocardial Infarction Rat Model.
Myocardial Infarction
The Role of ADAMTS1 and Versican in Human Myocardial Infarction: A Postmortem Study.
Myocardial Infarction
The role of von Willebrand factor and ADAMTS13 in the no-reflow phenomenon: after primary percutaneous coronary intervention.
nadph dehydrogenase deficiency
Effects of nitric oxide synthase deficiency on a disintegrin and metalloproteinase domain-containing protein 12 expression in mouse brain samples.
Nasal Polyps
A disintegrin and metalloprotease 10-containing exosomes derived from nasal polyps promote angiogenesis and vascular permeability.
Nasal Polyps
Expression of a disintegrin and metalloproteinase 8 by inflammatory cells in nasal polyps.
Neoplasm Metastasis
A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis.
Neoplasm Metastasis
Aberrant expression of disintegrin-metalloprotease proteins in the formation and progression of uterine cervical cancer.
Neoplasm Metastasis
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.
Neoplasm Metastasis
ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm.
Neoplasm Metastasis
ADAM-12 as a Diagnostic Marker for the Proliferation, Migration and Invasion in Patients with Small Cell Lung Cancer.
Neoplasm Metastasis
ADAM17-regulated CX3CL1 expression produced by bone marrow endothelial cells promotes spinal metastasis from hepatocellular carcinoma.
Neoplasm Metastasis
ADAM28 is a serological and histochemical marker for non-small-cell lung cancers.
Neoplasm Metastasis
ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis.
Neoplasm Metastasis
ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT.
Neoplasm Metastasis
ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis.
Neoplasm Metastasis
Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factor.
Neoplasm Metastasis
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Neoplasm Metastasis
Contortrostatin, a snake venom disintegrin, inhibits beta 1 integrin-mediated human metastatic melanoma cell adhesion and blocks experimental metastasis.
Neoplasm Metastasis
Control of specific growth rate to enhance the production of a novel disintegrin, saxatilin, in recombinant Pichia pastoris.
Neoplasm Metastasis
Downregulation of ADAMTS18 May Serve as a Poor Prognostic Biomarker for Cervical Cancer Patients.
Neoplasm Metastasis
Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor.
Neoplasm Metastasis
Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis.
Neoplasm Metastasis
EMMPRIN and ADAM12 in prostate cancer: preliminary results of a prospective study.
Neoplasm Metastasis
Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer.
Neoplasm Metastasis
Epigenetic regulation by Z-DNA silencer function controls cancer-associated ADAM-12 expression in breast cancer: cross-talk between MeCP2 and NF1 transcription factor family.
Neoplasm Metastasis
Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas.
Neoplasm Metastasis
Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively.
Neoplasm Metastasis
High expression of ADAMTS5 is a potent marker for lymphatic invasion and lymph node metastasis in colorectal cancer.
Neoplasm Metastasis
Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells.
Neoplasm Metastasis
Increased Expression of a Disintegrin and Metalloprotease-9 in Hepatocellular Carcinoma: Implications for Tumor Progression and Prognosis.
Neoplasm Metastasis
Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference.
Neoplasm Metastasis
Inhibition of ADAMTS1 Expression by Lentiviral CRISPR/Cas9 Gene Editing Technology.
Neoplasm Metastasis
Integrin alphavbeta3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line.
Neoplasm Metastasis
Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.
Neoplasm Metastasis
Methods for Evaluation of a Snake Venom-Derived Disintegrin in Animal Models of Human Cancer.
Neoplasm Metastasis
MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma.
Neoplasm Metastasis
miR-126 inhibits cell growth, invasion, and migration of osteosarcoma cells by downregulating ADAM-9.
Neoplasm Metastasis
Multi-organ metastasis as destination for breast cancer cells guided by biomechanical architecture.
Neoplasm Metastasis
Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer.
Neoplasm Metastasis
Overexpression of a disintegrin and metalloproteinase 21 is associated with motility, metastasis, and poor prognosis in hepatocellular carcinoma.
Neoplasm Metastasis
RNAi-mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non-small lung cancer in vitro and in vivo.
Neoplasm Metastasis
RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells.
Neoplasm Metastasis
Selective inhibition of ADAM28 suppresses lung carcinoma cell growth and metastasis.
Neoplasm Metastasis
SOX4, an epithelial-mesenchymal transition inducer, transactivates ADAM28 gene expression and co-localizes with ADAM28 at the invasive front of human breast and lung carcinomas.
Neoplasm Metastasis
Suppressive mechanism of salmosin, a novel disintegrin in B16 melanoma cell metastasis.
Neoplasm Metastasis
Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis.
Neoplasm Metastasis
Thalidomide combined with irradiation alters the activity of two proteases.
Neoplasm Metastasis
The disintegrin eristostatin interferes with integrin alpha 4 beta 1 function and with experimental metastasis of human melanoma cells.
Neoplasm Metastasis
The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone.
Neoplasm Metastasis
The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment.
Neoplasm Metastasis
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression.
Neoplasm Metastasis
Transcriptional control of PAX4-regulated miR-144/451 modulates metastasis by suppressing ADAMs expression.
Neoplasm Metastasis
Tumor invasion induced by oxidative stress is dependent on membrane ADAM 9 protein and its secreted form.
Neoplasm Metastasis
Upregulation of a Disintegrin and Metalloprotease 8 Influences Tumor Metastasis and Prognosis in Patients with Osteosarcoma.
Neoplasm Metastasis
[Expression and clinical significance of a disintegrin and metalloprotease 8 (ADAM8) and epidermal growth factor receptor (EGFR) in non-small cell lung cancer]
Neoplasms
A comparative pilot study of oral diacerein and locally treated diacerein-loaded nanoparticles in a model of osteoarthritis.
Neoplasms
A disintegrin and metalloprotease (ADAM)10 is highly expressed in hepatocellular carcinoma and is associated with tumour progression.
Neoplasms
A Disintegrin and Metalloprotease 15 is Expressed on Rheumatoid Arthritis Synovial Tissue Endothelial Cells and may Mediate Angiogenesis.
Neoplasms
A disintegrin and metalloprotease 17 promotes microglial cell survival via epidermal growth factor receptor signalling following spinal cord injury.
Neoplasms
A disintegrin and metalloprotease 23 hypermethylation predicts decreased disease-free survival in low-risk breast cancer patients.
Neoplasms
A disintegrin and metalloproteinase 9 is involved in ectodomain shedding of receptor-binding cancer antigen expressed on SiSo cells.
Neoplasms
A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling.
Neoplasms
A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [¹?F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging.
Neoplasms
A Novel TNF-? Converting Enzyme (TACE) Selective Inhibitor JTP-96193 Prevents Insulin Resistance in KK-Ay Type 2 Diabetic Mice and Diabetic Peripheral Neuropathy in Type 1 Diabetic Mice.
Neoplasms
A preliminary study: is fibulin 1 a friend or an enemy that needs to be silenced with siRNAs for mesothelioma?
Neoplasms
A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17.
Neoplasms
Aberrant expression of disintegrin-metalloprotease proteins in the formation and progression of uterine cervical cancer.
Neoplasms
Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis.
Neoplasms
ADAM 10 is over expressed in oral squamous cell carcinoma and contributes to invasive behaviour through a functional association with ?v?6 integrin.
Neoplasms
ADAM-12 as a Diagnostic Marker for the Proliferation, Migration and Invasion in Patients with Small Cell Lung Cancer.
Neoplasms
ADAM10 is overexpressed in human hepatocellular carcinoma and contributes to the proliferation, invasion and migration of HepG2 cells.
Neoplasms
ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing.
Neoplasms
ADAM12 and ADAM17 Gene Expression in Laser-capture Microdissected and Non-microdissected Breast Tumors.
Neoplasms
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Neoplasms
ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression.
Neoplasms
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis, and increased tumor growth.
Neoplasms
ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice.
Neoplasms
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease.
Neoplasms
ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction.
Neoplasms
ADAM17 but not ADAM10 mediates tumor necrosis factor-alpha and L-selectin shedding from leukocyte membranes.
Neoplasms
ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Neoplasms
Adam17, a Target of Mir-326, Promotes Emt-Induced Cells Invasion in Lung Adenocarcinoma.
Neoplasms
ADAM17-regulated CX3CL1 expression produced by bone marrow endothelial cells promotes spinal metastasis from hepatocellular carcinoma.
Neoplasms
ADAM17_i33708A>G polymorphism interacts with dietary n-6 polyunsaturated fatty acids to modulate obesity risk in the Genetics of Lipid Lowering Drugs and Diet Network study.
Neoplasms
ADAM23 in Cardiomyocyte Inhibits Cardiac Hypertrophy by Targeting FAK - AKT Signaling.
Neoplasms
ADAM28 is a serological and histochemical marker for non-small-cell lung cancers.
Neoplasms
ADAM8 expression in prostate cancer is associated with parameters of unfavorable prognosis.
Neoplasms
ADAM8 substrate specificity: Influence of pH on pre-processing and proteoglycan degradation.
Neoplasms
ADAM9 decreases in castration resistant prostate cancer and is a prognostic factor for overall survival.
Neoplasms
ADAM9 expression is a significant and independent prognostic marker of PSA relapse in prostate cancer.
Neoplasms
ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type, and Acts as a Prognostic Factor in Lower-Grade Gliomas.
Neoplasms
ADAM9 is highly expressed in renal cell cancer and is associated with tumour progression.
Neoplasms
ADAMTS-1 metalloproteinase promotes tumor development through the induction of a stromal reaction in vivo.
Neoplasms
ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse.
Neoplasms
ADAMTS13 and 15 are not regulated by the full length and N-terminal domain forms of TIMP-1, -2, -3 and -4.
Neoplasms
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-?B Pathway in Human Gastric Cancer.
Neoplasms
ADAMTS6 suppresses tumor progression via the ERK signaling pathway and serves as a prognostic marker in human breast cancer.
Neoplasms
ADAMTS8 Inhibits Cell Proliferation and Invasion, and Induces Apoptosis in Breast Cancer.
Neoplasms
ADAMTS8 targets ERK to suppress cell proliferation, invasion, and metastasis of hepatocellular carcinoma.
Neoplasms
Adipose tissue inflammation and liver fat in patients with highly active antiretroviral therapy-associated lipodystrophy.
Neoplasms
Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats.
Neoplasms
Allogenic Pure Platelet-Rich Plasma Therapy for Adhesive Capsulitis: A Bed-to-Bench Study With Propensity Score Matching Using a Corticosteroid Control Group.
Neoplasms
Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins.
Neoplasms
An Update on the Emerging Role of Visfatin in the Pathogenesis of Osteoarthritis and Pharmacological Intervention.
Neoplasms
Analysis of ADAM9 regulation and function in vestibular schwannoma primary cells.
Neoplasms
Angiostatic activity of obtustatin as alpha1beta1 integrin inhibitor in experimental melanoma growth.
Neoplasms
Angiotensin II and epidermal growth factor receptor cross-talk mediated by a disintegrin and metalloprotease accelerates tumor cell proliferation of hepatocellular carcinoma cell lines.
Neoplasms
Anti-invasive and anti-adhesive activities of a recombinant disintegrin, r-viridistatin 2, derived from the Prairie rattlesnake (Crotalus viridis viridis).
Neoplasms
Antiplatelet and anti-proliferative action of disintegrin from Echis multisquamatis snake venom.
Neoplasms
Antitumor and anti-angiogenic activity of the recombinant human disintegrin domain of A disintegrin and metalloproteinase 15.
Neoplasms
Associations between second-trimester amniotic fluid levels of ADAMTS4, ADAMTS5, IL-6, and TNF-? and spontaneous preterm delivery in singleton pregnancies.
Neoplasms
BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors.
Neoplasms
Baseline and decline of serum ADAM28 during chemotherapy of advanced non-small cell lung cancer: a probable predictive and prognostic factor.
Neoplasms
Bone morphogenetic protein-7 antagonizes tumor necrosis factor-?-induced activation of nuclear factor ?B and up-regulation of the ADAMTS, leading to decreased degradation of disc matrix macromolecules aggrecan and collagen II.
Neoplasms
Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine?disrupting chemicals.
Neoplasms
Caveolin-1-dependent activation of the metalloprotease TACE/ADAM17 by TGF-? in hepatocytes requires activation of Src and the NADPH oxidase NOX1.
Neoplasms
Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation.
Neoplasms
Cell-surface Metalloprotease ADAM12 is Internalized by a Clathrin- and Grb2-dependent Mechanism.
Neoplasms
Central and peripheral region tibial plateau chondrocytes respond differently to in vitro dynamic compression.
Neoplasms
Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme.
Neoplasms
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Neoplasms
Characterization of the Catalytic Properties of the Membrane-anchored Metalloprotease ADAM9 in Cell-based assays.
Neoplasms
Circadian Expression of TIMP3 Is Disrupted by UVB Irradiation and Recovered by Green Tea Extracts.
Neoplasms
Circulating ADAMs are associated with renal and cardiovascular outcomes in chronic kidney disease patients.
Neoplasms
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.
Neoplasms
Combined therapy with disintegrin and melphalan as a new strategy in inhibition of endometrial cancer cell line (Ishikawa) growth.
Neoplasms
Constitutive endocytosis of the chemokine, CX3CL1, prevents its degradation by cell surface metalloproteases.
Neoplasms
Contortrostatin, a homodimeric disintegrin, actively disrupts focal adhesion and cytoskeletal structure and inhibits cell motility through a novel mechanism.
Neoplasms
Contortrostatin, a snake venom disintegrin, induces alphavbeta3-mediated tyrosine phosphorylation of CAS and FAK in tumor cells.
Neoplasms
Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2.
Neoplasms
Control of specific growth rate to enhance the production of a novel disintegrin, saxatilin, in recombinant Pichia pastoris.
Neoplasms
Correlation between the histological grade of chondrosarcoma and the expression of MMPs, ADAMTSs and TIMPs.
Neoplasms
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Neoplasms
Decreased Cytoplasmic Expression of ADAMTS14 Is Correlated with Reduced Survival Rates in Oral Squamous Cell Carcinoma Patients.
Neoplasms
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.
Neoplasms
Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.
Neoplasms
Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state.
Neoplasms
Development of a novel recombinant disintegrin, contortrostatin, as an effective anti-tumor and anti-angiogenic agent.
Neoplasms
Differential regulation of tyrosine phosphorylation in tumor cells by contortrostatin, a homodimeric disintegrin, and monomeric disintegrins echistatin and flavoridin.
Neoplasms
Disintegrin tablysin-15 suppresses cancer hallmarks in melanoma cells by blocking FAK/Akt/ERK and NF-?B signaling.
Neoplasms
Disintegrins from snake venoms and their applications in cancer research and therapy.
Neoplasms
Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.
Neoplasms
DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells.
Neoplasms
Downregulation of ADAMTS18 May Serve as a Poor Prognostic Biomarker for Cervical Cancer Patients.
Neoplasms
Dynamic induction of ADAMTS1 gene in the early phase of acute myocardial infarction.
Neoplasms
Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor.
Neoplasms
Effect of tetramethylpyrazine combined with cisplatin on VEGF, KLF4 and ADAMTS1 in Lewis lung cancer mice.
Neoplasms
Effect of thrombin treatment of tumor cells on adhesion of tumor cells to platelets in vitro and tumor metastasis in vivo.
Neoplasms
Effects of ADAM10 and ADAM17 Inhibitors on Natural Killer Cell Expansion and Antibody-dependent Cellular Cytotoxicity Against Breast Cancer Cells
Neoplasms
Effects of biological drug adalimumab on tumour necrosis factor-alpha-converting enzyme activation.
Neoplasms
Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis.
Neoplasms
EMMPRIN and ADAM12 in prostate cancer: preliminary results of a prospective study.
Neoplasms
Epigenetic regulation by Z-DNA silencer function controls cancer-associated ADAM-12 expression in breast cancer: cross-talk between MeCP2 and NF1 transcription factor family.
Neoplasms
Epigenetic Regulation of a Disintegrin and Metalloproteinase (ADAM) Transcription in Colorectal Cancer Cells: Involvement of ?-Catenin, BRG1, and KDM4.
Neoplasms
Expression and Function of a Disintegrin and Metalloproteinases in Cancer-Associated Fibroblasts of Colorectal Cancer.
Neoplasms
Expression and function of tumour necrosis factor-alpha-converting enzyme in the central nervous system.
Neoplasms
Expression of a disintegrin and metalloprotease 8 and endostatin in human osteosarcoma: Implication in tumor progression and prognosis.
Neoplasms
Expression of A disintegrin and metalloprotease 8 is associated with cell growth and poor survival in colorectal cancer.
Neoplasms
Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas.
Neoplasms
Expression of the disintegrin metalloprotease, ADAM-10, in prostate cancer and its regulation by dihydrotestosterone, insulin-like growth factor I, and epidermal growth factor in the prostate cancer cell model LNCaP.
Neoplasms
Expression of tumor necrosis factor-alpha--converting enzyme and tumor necrosis factor-alpha in human myocarditis.
Neoplasms
Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma.
Neoplasms
Extracellular phosphorylation of collagen XVII by ecto-casein kinase 2 inhibits ectodomain shedding.
Neoplasms
Factor XII blockade inhibits aortic dilatation in angiotensin II-infused apolipoprotein E-deficient mice.
Neoplasms
Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and ?-catenin signaling.
Neoplasms
Full-length ADAMTS-1 and the ADAMTS-1 fragments display pro- and antimetastatic activity, respectively.
Neoplasms
Gene expression in SK-Mel-28 human melanoma cells treated with the snake venom jararhagin.
Neoplasms
Getting to the heart of the matter: osteoarthritis takes its place as part of the metabolic syndrome.
Neoplasms
Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-?B signaling pathway and activation of Akt signaling pathway.
Neoplasms
Glycosylation of a disintegrin and metalloprotease 17 affects its activity and inhibition.
Neoplasms
Glycyrrhizin inhibits osteoarthritis development through suppressing the PI3K/AKT/NF-?B signaling pathway in vivo and in vitro.
Neoplasms
Helping Eve overcome ADAM: G-quadruplexes in the ADAM-15 promoter as new molecular targets for breast cancer therapeutics.
Neoplasms
High expression of ADAMTS5 is a potent marker for lymphatic invasion and lymph node metastasis in colorectal cancer.
Neoplasms
High-density lipoprotein subfraction 3 decreases ADAMTS-1 expression induced by lipopolysaccharide and tumor necrosis factor-alpha in human endothelial cells.
Neoplasms
High-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation.
Neoplasms
Hormone-induced expression of tumor necrosis factor alpha-converting enzyme/A disintegrin and metalloprotease-17 impacts porcine cumulus cell oocyte complex expansion and meiotic maturation via ligand activation of the epidermal growth factor receptor.
Neoplasms
Human colonic myocytes are involved in postischemic inflammation through ADAM17-dependent TNFalpha production.
Neoplasms
Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells.
Neoplasms
Ibuprofen-loaded porous microspheres suppressed the progression of monosodium iodoacetate-induced osteoarthritis in a rat model.
Neoplasms
Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10).
Neoplasms
IL-21 Enhances the Degradation of Cartilage Through the JAK-STAT Signaling Pathway During Osteonecrosis of Femoral Head Cartilage.
Neoplasms
IL-21 Is Positively Associated with Intervertebral Disc Degeneration by Interaction with TNF-? Through the JAK-STAT Signaling Pathway.
Neoplasms
Impact of miR-SNP rs2910164 on miR-146a expression in osteoarthritic chondrocytes.
Neoplasms
Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding.
Neoplasms
Implication of TNF-alpha convertase (TACE/ADAM17) in inducible nitric oxide synthase expression and inflammation in an experimental model of colitis.
Neoplasms
In silico characterization of the interaction between LSKL peptide, a LAP-TGF-beta derived peptide, and ADAMTS1.
Neoplasms
In situ evidence of involvement of Schwann cells in ulcerative colitis: autocrine and paracrine signaling by A disintegrin and metalloprotease-17-mediated tumor necrosis factor alpha production.
Neoplasms
In Vitro Anti-Inflammation and Chondrogenic Differentiation Effects of Inclusion Nanocomplexes of Hyaluronic Acid-Beta Cyclodextrin and Simvastatin.
Neoplasms
In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progression.
Neoplasms
Increased Expression of a Disintegrin and Metalloprotease-9 in Hepatocellular Carcinoma: Implications for Tumor Progression and Prognosis.
Neoplasms
Increased mRNA expression of ADAMTS metalloproteinases in metastatic foci of head and neck cancer.
Neoplasms
Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions.
Neoplasms
Influence of an n-3 long-chain polyunsaturated fatty acid-enriched diet on experimentally induced synovitis in horses.
Neoplasms
Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference.
Neoplasms
Inhibition of ?v?3 integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC).
Neoplasms
Inhibition of ADAMTS1 Expression by Lentiviral CRISPR/Cas9 Gene Editing Technology.
Neoplasms
Inhibition of angiogenesis and tumor progression by hydrodynamic cotransfection of angiostatin K1-3, endostatin, and saxatilin genes.
Neoplasms
Inhibition of lung tumor colonization and cell migration with the disintegrin crotatroxin 2 isolated from the venom of Crotalus atrox.
Neoplasms
Inhibition of platelets and tumor cell adhesion by the disintegrin domain of human ADAM9 to collagen I under dynamic flow conditions.
Neoplasms
Inhibition of the tumor necrosis factor-alpha-converting enzyme by its pro domain.
Neoplasms
Inhibitory effect of the salmosin gene transferred by cationic liposomes on the progression of B16BL6 tumors.
Neoplasms
Inhibitory effects of MLDG-containing heterodimeric disintegrins reveal distinct structural requirements for interaction of the integrin alpha 9beta 1 with VCAM-1, tenascin-C, and osteopontin.
Neoplasms
Inhibitory effects of salmosin, a disintegrin, on posterior capsular opacification in vitro and in vivo.
Neoplasms
iNOS promotes CD24+CD133+ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway.
Neoplasms
Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.
Neoplasms
Integrin alphavbeta3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line.
Neoplasms
Interactions between tumour cells and stromal cells and proteolytic modification of the extracellular matrix by metalloproteinases in cancer.
Neoplasms
Interferon-gamma down-regulates expression of tumor necrosis factor-alpha converting enzyme/a disintegrin and metalloproteinase 17 in activated hepatic stellate cells of rats.
Neoplasms
Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes.
Neoplasms
Involvement of NF-kappaB-mediated maturation of ADAM-17 in the invasion of oral squamous cell carcinoma.
Neoplasms
Joint Entropy-Assisted Graphene Oxide-Based Multiplexing Biosensing Platform for Simultaneous Detection of Multiple Proteases.
Neoplasms
Knockout of ADAM10 enhances sorafenib antitumor activity of hepatocellular carcinoma in vitro and in vivo.
Neoplasms
Leucurogin, a new recombinant disintegrin cloned from Bothrops leucurus (white-tailed-jararaca) with potent activity upon platelet aggregation and tumor growth.
Neoplasms
Ligand-dependent activation of the epidermal growth factor receptor by secondary bile acids in polarizing colon cancer cells.
Neoplasms
Low levels of ADAM23 expression in epithelial ovarian cancer are associated with poor survival.
Neoplasms
Matrix metalloproteinases and TACE play a role in the pathogenesis of endometriosis.
Neoplasms
Melatonin-triggered post-transcriptional and post-translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma.
Neoplasms
Membrane-anchored CD40 is processed by the tumor necrosis factor-alpha-converting enzyme. Implications for CD40 signaling.
Neoplasms
Metalloprotease-disintegrin ADAM 12 binds to the SH3 domain of Src and activates Src tyrosine kinase in C2C12 cells.
Neoplasms
Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30.
Neoplasms
Methods for Evaluation of a Snake Venom-Derived Disintegrin in Animal Models of Human Cancer.
Neoplasms
MicroRNA-21-5p are involved in apoptosis and invasion of fibroblast-like synoviocytes through PTEN/PI3K/AKT signal.
Neoplasms
miR-126 inhibits cell growth, invasion, and migration of osteosarcoma cells by downregulating ADAM-9.
Neoplasms
Modeling of enzyme-substrate complexes for the metalloproteases MMP-3, ADAM-9 and ADAM-10.
Neoplasms
Modulation of the microenvironment and adhesion of cancer cells by ADAMs (a disintegrin and metalloproteinase).
Neoplasms
Molecular insights into the multilayered regulation of ADAM17: The role of the extracellular region.
Neoplasms
Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer.
Neoplasms
Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells.
Neoplasms
Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Neoplasms
Neutralization of ADAM8 ameliorates liver injury and accelerates liver repair in carbon tetrachloride-induced acute liver injury.
Neoplasms
Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer.
Neoplasms
Opposite Roles of CCR2 and CX3CR1 Macrophages in Alkali-Induced Corneal Neovascularization.
Neoplasms
Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer.
Neoplasms
Overexpression of a disintegrin and metalloprotease 8 in human gliomas is implicated in tumor progression and prognosis.
Neoplasms
Overexpression of A disintegrin and metalloproteinase 28 is correlated with high histologic grade in conventional chondrosarcoma.
Neoplasms
Overexpression of ADAM9 in non-small cell lung cancer correlates with brain metastasis.
Neoplasms
Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers.
Neoplasms
Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain.
Neoplasms
Phylogenetic and molecular evolution of the ADAM (A Disintegrin And Metalloprotease) gene family from Xenopus tropicalis, to Mus musculus, Rattus norvegicus, and Homo sapiens.
Neoplasms
Plasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors.
Neoplasms
Polymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cells.
Neoplasms
Potent mimicry of fibronectin-induced intracellular signaling in glioma cells by the homodimeric snake venom disintegrin contortrostatin.
Neoplasms
Pro-tumor necrosis factor-alpha processing activity is tightly controlled by a component that does not affect notch processing.
Neoplasms
Processing of tumor necrosis factor by the membrane-bound TNF-alpha-converting enzyme, but not its truncated soluble form.
Neoplasms
Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis.
Neoplasms
Prognostic Values for the mRNA Expression of the ADAMTS Family of Genes in Gastric Cancer.
Neoplasms
Proinflammatory cytokines regulate tissue inhibitors of metalloproteinases and disintegrin metalloproteinase in cardiac cells.
Neoplasms
Protein processing mechanisms: from angiotensin-converting enzyme to Alzheimer's disease.
Neoplasms
Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis.
Neoplasms
Rebamipide reduces amyloid-? 1-42 (A?42) production and ameliorates A?43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.
Neoplasms
Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells.
Neoplasms
Recombinant disintegrin domain of human ADAM9 inhibits migration and invasion of DU145 prostate tumor cells.
Neoplasms
Regulation of the inflammatory cycle by a controllable release hydrogel for eliminating postoperative inflammation after discectomy.
Neoplasms
Regulatory effect of nerve growth factor in alpha9beta1 integrin-dependent progression of glioblastoma.
Neoplasms
Regulatory effect of nerve growth factor in {alpha}9{beta}1 integrin-dependent progression of glioblastoma.
Neoplasms
Relationship Between ADAMTS8, ADAMTS18, and ADAMTS20 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) Expressions and Tumor Molecular Classification, Clinical Pathological Parameters, and Prognosis in Breast Invasive Ductal Carcinoma.
Neoplasms
Relationships between early inflammatory response to bleomycin and sensitivity to lung fibrosis: a role for dipeptidyl-peptidase I and tissue inhibitor of metalloproteinase-3?
Neoplasms
Relative efficacies of omega-3 polyunsaturated fatty acids in reducing expression of key proteins in a model system for studying osteoarthritis.
Neoplasms
RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction.
Neoplasms
Rhodocetin antagonizes stromal tumor invasion in vitro and other alpha2beta1 integrin-mediated cell functions.
Neoplasms
Rhodostomin, a snake venom disintegrin, inhibits angiogenesis elicited by basic fibroblast growth factor and suppresses tumor growth by a selective alpha(v)beta(3) blockade of endothelial cells.
Neoplasms
RNAi-mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non-small lung cancer in vitro and in vivo.
Neoplasms
RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells.
Neoplasms
Role of TIMPs (tissue inhibitors of metalloproteinases) in pericellular proteolysis: the specificity is in the detail.
Neoplasms
Saxatilin inhibits TNF-alpha-induced proliferation by suppressing AP-1-dependent IL-8 expression in the ovarian cancer cell line MDAH 2774.
Neoplasms
Saxatilin, a snake venom disintegrin, suppresses TNF-alpha-induced ovarian cancer cell invasion.
Neoplasms
Scutellarin Attenuates the IL-1?-Induced Inflammation in Mouse Chondrocytes and Prevents Osteoarthritic Progression.
Neoplasms
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).
Neoplasms
Selective inhibition of ADAM28 suppresses lung carcinoma cell growth and metastasis.
Neoplasms
Shedding of collagen XVII ectodomain depends on plasma membrane microenvironment.
Neoplasms
Shedding of endogenous MHC class I-related chain molecules A and B (MICA and MICB) from different human tumor entities: Heterogeneous involvement of the a disintegrin and metalloproteases 10 and 17 (ADAM10 and ADAM17).
Neoplasms
Short hairpin RNA-mediated gene silencing of ADAM17 inhibits the growth of breast cancer MCF?7 cells in vitro and in vivo and its mechanism of action.
Neoplasms
SRC fine-tunes ADAM10 shedding activity to promote pituitary adenoma cell progression.
Neoplasms
Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer.
Neoplasms
Structural characterization of the ectodomain of a disintegrin and metalloproteinase-22 (ADAM22), a neural adhesion receptor instead of metalloproteinase: insights on ADAM function.
Neoplasms
Substrate specificity and inducibility of TACE (tumour necrosis factor alpha-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activity.
Neoplasms
Suppressive mechanism of salmosin, a novel disintegrin in B16 melanoma cell metastasis.
Neoplasms
Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis.
Neoplasms
Syzygium Polyanthum Reduced TNF-? and ADAM17 Protein Expression in Myocardial Infarction Rat Model.
Neoplasms
TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.
Neoplasms
TACE/ADAM-17 enzymatic activity is increased in response to cellular stimulation.
Neoplasms
Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency.
Neoplasms
Targeting of extracellular proteases required for the progression of pancreatic cancer.
Neoplasms
Targeting the heparin-binding epidermal growth factor-like growth factor in ovarian cancer therapy.
Neoplasms
Temporal and spatial patterns of ovarian gene transcription following an ovulatory dose of gonadotropin in the rat.
Neoplasms
The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM.
Neoplasms
The Blockade of TACE-Dependent EGF Receptor Activation by Losartan-Erlotinib Combination Attenuates Renal Fibrosis Formation in 5/6-Nephrectomized Rats Under Vitamin D Deficiency.
Neoplasms
The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-?-Induced Epithelial to Mesenchymal Transition.
Neoplasms
The disintegrin and metalloprotease Meltrin from Drosophila forms oligomers via its protein binding domain and is regulated by the homeobox protein VND during embryonic development.
Neoplasms
The disintegrin domain of ADAM17 antagonises fibroblast?carcinoma cell interactions.
Neoplasms
The disintegrin tzabcanin inhibits adhesion and migration in melanoma and lung cancer cells.
Neoplasms
The disintegrin-metalloproteinases ADAM 10, 12 and 17 are upregulated in invading peripheral tumor cells of basal cell carcinomas.
Neoplasms
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein.
Neoplasms
The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activation.
Neoplasms
The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer.
Neoplasms
The expression of ADAM23 and its correlation with promoter methylation in non-small-cell lung carcinoma.
Neoplasms
The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone.
Neoplasms
The Importance of the Knee Joint Meniscal Fibrocartilages as Stabilizing Weight Bearing Structures Providing Global Protection to Human Knee-Joint Tissues.
Neoplasms
The role of contortrostatin, a snake venom disintegrin, in the inhibition of tumor progression and prolongation of survival in a rodent glioma model.
Neoplasms
The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment.
Neoplasms
The role of novel cytokines in inflammation: Defining peripheral artery disease among patients with coronary artery disease.
Neoplasms
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression.
Neoplasms
The t(14,15) in mouse strain CBA/CaH-T(14;15)6Ca/J causes a break in the ADAMTS12 gene.
Neoplasms
The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress.
Neoplasms
Three Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.
Neoplasms
Tobacco smoke-induced lung cell proliferation mediated by tumor necrosis factor alpha-converting enzyme and amphiregulin.
Neoplasms
Transcriptional control of PAX4-regulated miR-144/451 modulates metastasis by suppressing ADAMs expression.
Neoplasms
Transforming growth factor-beta1-mediated activation of NF-kappaB contributes to enhanced ADAM-12 expression in mammary carcinoma cells.
Neoplasms
Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility.
Neoplasms
Tumor invasion induced by oxidative stress is dependent on membrane ADAM 9 protein and its secreted form.
Neoplasms
Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function.
Neoplasms
Tumor necrosis factor-? induces ADAMTS-4 expression in human osteoarthritis chondrocytes.
Neoplasms
Tumor necrosis factor-alpha converting enzyme is processed by proprotein-convertases to its mature form which is degraded upon phorbol ester stimulation.
Neoplasms
Tumor necrosis factor-alpha converting enzyme: Implications for ocular inflammatory diseases.
Neoplasms
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Neoplasms
Up-regulated expression of ADAM17 in gastrointestinal stromal tumors: coexpression with EGFR and EGFR ligands.
Neoplasms
Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices.
Neoplasms
Upregulated expression of ADAM12 is associated with progression of oral squamous cell carcinoma.
Neoplasms
Upregulation of a Disintegrin and Metalloprotease 8 Influences Tumor Metastasis and Prognosis in Patients with Osteosarcoma.
Neoplasms
Upregulation of a disintegrin and metalloprotease 8 is associated with progression and prognosis of patients with gastric cancer.
Neoplasms
Upregulation of ADAM12 contributes to accelerated cell proliferation and cell adhesion-mediated drug resistance (CAM-DR) in Non-Hodgkin's Lymphoma.
Neoplasms
Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities.
Neoplasms
When spider and snake get along: Fusion of a snake disintegrin with a spider phospholipase D to explore their synergistic effects on a tumor cell.
Neoplasms
[Expression and clinical significance of a disintegrin and metalloprotease 8 (ADAM8) and epidermal growth factor receptor (EGFR) in non-small cell lung cancer]
Neoplasms
[Inhibition of proliferation, adhesion and invasion ability of human lung carcinoma cell A549 by tumor necrosis factor-alpha converting enzyme (TACE)]
Nephrosis
Effects of Shenkangling intervention on the MAPK pathway in rats with doxorubicin-induced nephropathy.
Neuritis
The disintegrin domain of ADAM 8 enhances protection against rat experimental autoimmune encephalomyelitis, neuritis and uveitis by a polyvalent autoantigen vaccine.
Neuroblastoma
Activin receptor signaling regulates prostatic epithelial cell adhesion and viability.
Neuroblastoma
PI3-K- and PKC-dependent up-regulation of APP processing enzymes by retinoic acid.
Neurodegenerative Diseases
Activation of Kinin B1R Upregulates ADAM17 and Results in ACE2 Shedding in Neurons.
Neurodegenerative Diseases
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases.
Neurodegenerative Diseases
Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice.
Neuroinflammatory Diseases
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases.
Neuroinflammatory Diseases
Metalloprotease Adam10 suppresses epilepsy through repression of hippocampal neuroinflammation.
Neuroma, Acoustic
Analysis of ADAM9 regulation and function in vestibular schwannoma primary cells.
Odontogenic Cysts
HIF-1? is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1? and NOTCH1 Signaling Pathways.
Oligodendroglioma
Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity.
Osteoarthritis
ADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'.
Osteoarthritis
ADAMTS4 (aggrecanase-1) interaction with the C-terminal domain of fibronectin inhibits proteolysis of aggrecan.
Osteoarthritis
Aggravation of ADAMTS and Matrix Metalloproteinase Production and Role of ERK1/2 Pathway in the Interaction of Osteoarthritic Subchondral Bone Osteoblasts and Articular Cartilage Chondrocytes -- Possible Pathogenic Role in Osteoarthritis.
Osteoarthritis
An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2.
Osteoarthritis
Association of ADAM12-S protein with radiographic features of knee osteoarthritis and bone and cartilage markers.
Osteoarthritis
CD11c+ macrophages and levels of TNF-? and MMP-3 are increased in synovial and adipose tissues of osteoarthritic mice with hyperlipidemia.
Osteoarthritis
Changes in immunolocalisation of beta-dystroglycan and specific degradative enzymes in the osteoarthritic synovium.
Osteoarthritis
Detection of ADAMTS-4 activity using a fluorogenic peptide-conjugated Au nanoparticle probe in human knee synovial fluid.
Osteoarthritis
Development of human neutralizing antibody to ADAMTS4 (aggrecanase-1) and ADAMTS5 (aggrecanase-2).
Osteoarthritis
Diagnostic utility of fluorogenic peptide-conjugated Au nanoparticle probe corroborated by rabbit model of mild cartilage injury and panel of osteoarthritic patients.
Osteoarthritis
Effect of inhibiting MMP13 and ADAMTS5 by intra-articular injection of small interfering RNA in a surgically induced osteoarthritis model of mice.
Osteoarthritis
Effect of osteopontin on TIMP-1 and TIMP-2 mRNA in chondrocytes of human knee osteoarthritis in vitro.
Osteoarthritis
Emodin ameliorates cartilage degradation in osteoarthritis by inhibiting NF-?B and Wnt/?-catenin signaling in-vitro and in-vivo.
Osteoarthritis
Evaluating the Effects of Platelet-Rich Plasma and Amniotic Viscous Fluid on Inflammatory Markers in a Human Coculture Model for Osteoarthritis.
Osteoarthritis
Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage.
Osteoarthritis
Getting to the heart of the matter: osteoarthritis takes its place as part of the metabolic syndrome.
Osteoarthritis
Guava leaf extract suppresses osteoarthritis progression in a rat anterior cruciate ligament transection model.
Osteoarthritis
Healthy and Osteoarthritic Synovial Fibroblasts Produce a Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, 5, 7, and 12: Induction by IL-1? and Fibronectin and Contribution to Cartilage Damage.
Osteoarthritis
Highly enhanced expression of the disintegrin metalloproteinase MDC15 (metargidin) in rheumatoid synovial tissue.
Osteoarthritis
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling.
Osteoarthritis
Intra-articular injection of hyaluronan prevents cartilage erosion, periarticular fibrosis and mechanical allodynia and normalizes stance time in murine knee osteoarthritis.
Osteoarthritis
Leptin induces ADAMTS-4, ADAMTS-5, and ADAMTS-9 genes expression by mitogen-activated protein kinases and NF-?B signaling pathways in human chondrocytes.
Osteoarthritis
Long non-coding RNA HOTAIR promotes expression of ADAMTS-5 in human osteoarthritic articular chondrocytes.
Osteoarthritis
Low-density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4: Functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
Osteoarthritis
Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1.
Osteoarthritis
MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1?-Induced Catabolism in Human Articular Chondrocytes.
Osteoarthritis
Nesfatin-1 suppresses interleukin-1?-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats.
Osteoarthritis
Nobiletin, a citrus polymethoxy flavonoid, suppresses gene expression and production of aggrecanases-1 and -2 in collagen-induced arthritic mice.
Osteoarthritis
Osteoblasts Regulate the Expression of ADAMTS and MMPs in Chondrocytes through ERK Signaling Pathway.
Osteoarthritis
Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding.
Osteoarthritis
Quercetin prevent proteoglycan destruction by inhibits matrix metalloproteinase-9, matrix metalloproteinase-13, a disintegrin and metalloproteinase with thrombospondin motifs-5 expressions on osteoarthritis model rats.
Osteoarthritis
Salicin inhibits AGE-induced degradation of type II collagen and aggrecan in human SW1353 chondrocytes: therapeutic potential in osteoarthritis.
Osteoarthritis
SOX9 is a regulator of ADAMTSs-induced cartilage degeneration at the early stage of human osteoarthritis.
Osteoarthritis
Structural modeling of osteoarthritis ADAMTS4 complex with its cognate inhibitory protein TIMP3 and rational derivation of cyclic peptide inhibitors from the complex interface to target ADAMTS4.
Osteoarthritis
Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis.
Osteoarthritis
The alteration of A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) in the knee joints of osteoarthritis mice.
Osteoarthritis
The IL-1?/AP-1/miR-30a/ADAMTS-5 axis regulates cartilage matrix degradation in human osteoarthritis.
Osteoarthritis
The interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis.
Osteoarthritis
The role of increased synovial fluid A disintegrin and metalloproteinase with thrombospondin motifs4 and serglycin levels in osteoarthritis.
Osteoarthritis
Tumor necrosis factor-? induces ADAMTS-4 expression in human osteoarthritis chondrocytes.
Osteoarthritis
VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts.
Osteoarthritis
[Research progress of a disintegrin and metalloproteinase with thrombospondin motif 4 and 5 in osteoarthritis].
Osteoarthritis, Knee
Increased serum ADAMTS-4 in knee osteoarthritis: a potential indicator for the diagnosis of osteoarthritis in early stages.
Osteoarthritis, Knee
Quantitation OF ARGS aggrecan fragments in synovial fluid, serum and urine from osteoarthritis patients.
Osteoarthritis, Knee
Relationship between ADAMTS14/rs4747096 gene polymorphism and knee osteoarthritis in Chinese population.
Osteoarthritis, Knee
The utility of synovial fluid levels of ADAMTS9 and ADAMTS4 in predicting treatment responses to intraarticular steroid injections in patients with knee osteoarthritis
Osteopetrosis
Multi-trait GWAS using imputed high-density genotypes from whole-genome sequencing identifies genes associated with body traits in Nile tilapia.
Osteophyte
An Update on the Emerging Role of Visfatin in the Pathogenesis of Osteoarthritis and Pharmacological Intervention.
Osteoporosis
Inhibition of osteoporosis by the ?v?3 integrin antagonist of rhodostomin variants.
Osteosarcoma
Differential expression of degradome components in cutaneous squamous cell carcinomas.
Osteosarcoma
Disintegrin targeting of an ?v?3 integrin-over-expressing high-metastatic human osteosarcoma with Echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro.
Osteosarcoma
Expression of a disintegrin and metalloprotease 8 and endostatin in human osteosarcoma: Implication in tumor progression and prognosis.
Osteosarcoma
Function of the cysteine-rich domain of the haemorrhagic metalloproteinase atrolysin A: targeting adhesion proteins collagen I and von Willebrand factor.
Osteosarcoma
IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway.
Osteosarcoma
Synergistic suppression of a disintegrin acurhagin-C in combination with AZD4547 and reparixin on terminating development for human osteosarcoma MG-63 cell.
Osteosarcoma
The disintegrin echistatin in combination with doxorubicin targets high-metastatic human osteosarcoma overexpressing ???3 integrin in chick embryo and nude mouse models.
Osteosarcoma
Upregulation of a Disintegrin and Metalloprotease 8 Influences Tumor Metastasis and Prognosis in Patients with Osteosarcoma.
Ovarian Neoplasms
A novel snake venom disintegrin that inhibits human ovarian cancer dissemination and angiogenesis in an orthotopic nude mouse model.
Ovarian Neoplasms
Aberrant expression of ADAM9 in ovarian cancer and its clinical significance.
Ovarian Neoplasms
Control of specific growth rate to enhance the production of a novel disintegrin, saxatilin, in recombinant Pichia pastoris.
Ovarian Neoplasms
Integrin alphavbeta3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line.
Ovarian Neoplasms
Lysophosphatidic acid induces tumor necrosis factor-alpha to regulate a pro-inflammatory cytokine network in ovarian cancer.
Ovarian Neoplasms
Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Ovarian Neoplasms
Saxatilin, a snake venom disintegrin, suppresses TNF-alpha-induced ovarian cancer cell invasion.
Ovarian Neoplasms
Targeting the heparin-binding epidermal growth factor-like growth factor in ovarian cancer therapy.
Ovarian Neoplasms
The role of CDCP1 (CUB domain-containing protein 1) and ADAM12 (a disintegrin and metalloproteinase 12) in ovarian cancer.
Pancreatic Neoplasms
ADAM9 Mediates Triple-Negative Breast Cancer Progression via AKT/NF-?B Pathway.
Pancreatic Neoplasms
Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression.
Pancreatic Neoplasms
Bone Marrow Mesenchymal Stem Cell-Derived Exosomal MicroRNA-126-3p Inhibits Pancreatic Cancer Development by Targeting ADAM9.
Pancreatic Neoplasms
Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and ?-catenin signaling.
Pancreatic Neoplasms
Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: role of circ_0000977/miR-153 axis.
Pancreatic Neoplasms
Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Pancreatic Neoplasms
Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.
Pancreatic Neoplasms
Recombinant disintegrin (r-Cam-dis) from Crotalus adamanteus inhibits adhesion of human pancreatic cancer cell lines to laminin-1 and vitronectin.
Paramyxoviridae Infections
Human parainfluenza virus type 2 (HPIV2) induced host ADAM8 expression in human salivary adenocarcinoma cell line (HSY) during cell fusion.
Periodontal Diseases
Comparative analysis of gingival crevicular fluid a disintegrin and metalloproteinase 8 levels in health and periodontal disease: A clinic-biochemical study.
Periodontal Diseases
Elevated Levels of A Disintegrin and Metalloproteinase 8 in Gingival Crevicular Fluid of Patients With Periodontal Diseases.
Periodontitis
Periodontitis Deteriorates Cognitive Function and Impairs Neurons and Glia in a Mouse Model of Alzheimer's Disease.
Peripheral Arterial Disease
Modulation of miR29a improves impaired post-ischemic angiogenesis in hyperglycemia.
Peripheral Nerve Injuries
Inhibition of neuropathic pain by a potent disintegrin--triflavin.
Pituitary Neoplasms
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Pneumonia
ADAM-family metalloproteinases in lung inflammation: potential therapeutic targets.
Pneumonia
Angiotensin-(1-7)/Mas Signaling Inhibits Lipopolysaccharide-Induced ADAM17 Shedding Activity and Apoptosis in Alveolar Epithelial Cells.
Pneumonia
Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space.
Pneumonia
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Polycystic Kidney Diseases
A Disintegrin and Metalloenzyme (ADAM) 17 Activation Is Regulated by ?5?1 Integrin in Kidney Mesangial Cells.
Polycystic Kidney Diseases
ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.
Polycystic Kidney Diseases
The epidermal growth factor receptor pathway in chronic kidney diseases.
Polycystic Kidney, Autosomal Dominant
The epidermal growth factor receptor pathway in chronic kidney diseases.
Polycystic Kidney, Autosomal Recessive
ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.
Polycythemia Vera
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Pre-Eclampsia
ADAMTS 1, 4, 12, and 13 levels in maternal blood, cord blood, and placenta in preeclampsia.
Pre-Eclampsia
First-trimester maternal serum a disintegrin and metalloprotease 12 (ADAM12) and adverse pregnancy outcome.
Pre-Eclampsia
Limitations of ADAMTS-13 Activity Level in Diagnosing Thrombotic Thrombocytopenic Purpura in Pregnancy.
Pre-Eclampsia
The value of early second trimester PAPP-A and ADAM12 in screening for pre-eclampsia.
Pregnancy, Ectopic
A disintegrin and metalloprotease protein-12 as a novel marker for the diagnosis of ectopic pregnancy.
Pregnancy, Ectopic
Maternal serum disintegrin and metalloprotease protein-12 in early pregnancy as a potential marker of adverse pregnancy outcomes.
Premature Birth
Associations between second-trimester amniotic fluid levels of ADAMTS4, ADAMTS5, IL-6, and TNF-? and spontaneous preterm delivery in singleton pregnancies.
Prion Diseases
Apparent Reduction of ADAM10 in Scrapie-Infected Cultured Cells and in the Brains of Scrapie-Infected Rodents.
Prostatic Neoplasms
ADAM15 supports prostate cancer metastasis by modulating tumor cell-endothelial cell interaction.
Prostatic Neoplasms
ADAM9 expression is a significant and independent prognostic marker of PSA relapse in prostate cancer.
Prostatic Neoplasms
CD82 Suppresses ADAM17-Dependent E-Cadherin Cleavage and Cell Migration in Prostate Cancer.
Prostatic Neoplasms
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Prostatic Neoplasms
Combined Dynamic Alterations in Urinary VEGF Levels and Tissue ADAM9 Expression as Markers for Lethal Phenotypic Progression of Prostate Cancer.
Prostatic Neoplasms
Expression of the disintegrin metalloprotease, ADAM-10, in prostate cancer and its regulation by dihydrotestosterone, insulin-like growth factor I, and epidermal growth factor in the prostate cancer cell model LNCaP.
Prostatic Neoplasms
Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.
Prostatic Neoplasms
Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer.
Prostatic Neoplasms
Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers.
Prostatic Neoplasms
Phorbol ester-induced shedding of the prostate cancer marker transmembrane protein with epidermal growth factor and two follistatin motifs 2 is mediated by the disintegrin and metalloproteinase-17.
Prostatic Neoplasms
Preclinical evaluation of a 64Cu-labeled disintegrin for PET imaging of prostate cancer.
Prostatic Neoplasms
The disintegrin contortrostatin in combination with docetaxel is a potent inhibitor of prostate cancer in vitro and in vivo.
Prostatic Neoplasms
The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression.
Psoriasis
ADAM33 as a Psoriasis Susceptibility Gene in the Han Population of Northeastern China.
Psoriasis
Autoantigens ADAMTSL5 and LL37 are significantly upregulated in active Psoriasis and localized with keratinocytes, dendritic cells and other leukocytes.
Pulmonary Disease, Chronic Obstructive
A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD.
Pulmonary Disease, Chronic Obstructive
A disintegrin and metalloprotease 33 and chronic obstructive pulmonary disease pathophysiology.
Pulmonary Disease, Chronic Obstructive
A disintegrin and metalloprotease 33 polymorphism association with COPD in long-term tobacco smokers of the ethnic Kashmiri population of India.
Pulmonary Disease, Chronic Obstructive
A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice.
Pulmonary Disease, Chronic Obstructive
A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
ADAM17 Deficiency Protects against Pulmonary Emphysema.
Pulmonary Disease, Chronic Obstructive
ADAM33 gene polymorphisms in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Association between F+1 polymorphism in a disintegrin and metalloprotease 33 (ADAM33) gene and chronic obstructive pulmonary disease susceptibility: An evidence-based meta-analysis.
Pulmonary Disease, Chronic Obstructive
Association of a disintegrin and metalloprotease 33 (ADAM33) gene polymorphisms with the risk of COPD: an updated meta-analysis of 2,644 cases and 4,804 controls.
Pulmonary Disease, Chronic Obstructive
Association of a disintegrin and metalloproteinase 33 (ADAM33) gene polymorphisms with chronic obstructive pulmonary disease in the Chinese population: a meta-analysis.
Pulmonary Disease, Chronic Obstructive
DNA sequence variations of metalloproteinases: their role in asthma and COPD.
Pulmonary Disease, Chronic Obstructive
Genetic Variants in IL6R and ADAM19 are Associated with COPD Severity in a Mexican Mestizo Population.
Pulmonary Disease, Chronic Obstructive
Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications.
Pulmonary Disease, Chronic Obstructive
Polymorphisms in a disintegrin and metalloprotease 33 gene and the risk of chronic obstructive pulmonary disease: A meta-analysis.
Pulmonary Disease, Chronic Obstructive
Predictive value of ADAMTS-13 on concealed chronic renal failure in COPD patients.
Pulmonary Disease, Chronic Obstructive
Role of aberrant metalloproteinase activity in the pro-inflammatory phenotype of bronchial epithelium in COPD.
Pulmonary Disease, Chronic Obstructive
Serological investigation of the collagen degradation profile of patients with chronic obstructive pulmonary disease or idiopathic pulmonary fibrosis.
Pulmonary Disease, Chronic Obstructive
The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma.
Pulmonary Disease, Chronic Obstructive
[Association of the MMP3, MMP9, ADAM33 and TIMP3 genes polymorphic markers with development and progression of chronic obstructive pulmonary disease].
Pulmonary Eosinophilia
Increased serum ADAM8 concentration in patients with drug-induced eosinophilic pneumonia-ADAM8 expression depends on a the allergen route of entry.
Purpura
Congenital thrombotic thrombocytopenic purpura presenting in adulthood with recurrent cerebrovascular events.
Purpura
Effectiveness of Caplacizumab Nanobody in Acquired Thrombotic Thrombocytopenic Purpura Refractory to Conventional Treatment.
Purpura
Emerging roles of adjunct therapies in acquired thrombotic thrombocytopenia purpura.
Purpura
Limitations of ADAMTS-13 Activity Level in Diagnosing Thrombotic Thrombocytopenic Purpura in Pregnancy.
Purpura, Thrombocytopenic, Idiopathic
A successfully treated case of an acute presentation of congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) with decreased ADAMTS13 during late stage of pregnancy.
Purpura, Thrombotic Thrombocytopenic
A human monoclonal antibody against the distal carboxyl terminus of ADAMTS-13 modulates its susceptibility to an inhibitor in thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
A multicenter laboratory assessment of a new automated chemiluminescent assay for ADAMTS13 activity.
Purpura, Thrombotic Thrombocytopenic
A new mouse model mimicking thrombotic thrombocytopenic purpura: correction of symptoms by recombinant human ADAMTS13.
Purpura, Thrombotic Thrombocytopenic
Absence of exaggerated pharmacology by recombinant ADAMTS13 in the rat and monkey.
Purpura, Thrombotic Thrombocytopenic
ADAMTS-13 antigen and activity levels in thrombocytopenic disorders including thrombotic thrombocytopenic purpura in Kuwait.
Purpura, Thrombotic Thrombocytopenic
ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies.
Purpura, Thrombotic Thrombocytopenic
ADAMTS13 related markers and von Willebrand factor in plasma from patients with thrombotic microangiopathy (TMA).
Purpura, Thrombotic Thrombocytopenic
ADAMTS13 Secretion and Residual Activity among Patients with Congenital Thrombotic Thrombocytopenic Purpura with and without Renal Impairment.
Purpura, Thrombotic Thrombocytopenic
Aggressive Disease and Rare Sequelae in a Unique Case of Atypical Hemolytic Uremic Syndrome Secondary to Adult Onset Still's Disease.
Purpura, Thrombotic Thrombocytopenic
Anti-ADAMTS13 Autoantibodies against Cryptic Epitopes in Immune-Mediated Thrombotic Thrombocytopenic Purpura.
Purpura, Thrombotic Thrombocytopenic
Anti-ADAMTS13 autoantibody profiling in patients with immune-mediated thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Atypical hemolytic uremic syndrome: a syndrome in need of clarity.
Purpura, Thrombotic Thrombocytopenic
Bethesda Assay for Detecting Inhibitory Anti-ADAMTS13 Antibodies in Immune-Mediated Thrombotic Thrombocytopenic Purpura.
Purpura, Thrombotic Thrombocytopenic
Bortezomib in the treatment of refractory thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Caplacizumab to treat immune-mediated thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
CD4+ T cells from patients with acquired thrombotic thrombocytopenic purpura recognize CUB2 domain-derived peptides.
Purpura, Thrombotic Thrombocytopenic
Chest pain with increased troponin level; not always a cardiology issue.
Purpura, Thrombotic Thrombocytopenic
Child-onset and adolescent-onset acquired thrombotic thrombocytopenic purpura with severe ADAMTS13 deficiency: a cohort study of the French national registry for thrombotic microangiopathy.
Purpura, Thrombotic Thrombocytopenic
Cholangiocarcinoma presenting with acquired thrombotic thrombocytopenic purpura confirmed by positive autoantibodies of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13.
Purpura, Thrombotic Thrombocytopenic
Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies.
Purpura, Thrombotic Thrombocytopenic
Clinical features and outcomes in patients with thrombotic microangiopathy not associated with severe ADAMTS13 deficiency.
Purpura, Thrombotic Thrombocytopenic
Comparison of Rituximab originator (MabThera) to biosimilar (Truxima) in patients with immune-mediated thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Congenital Thrombotic Thrombocytopenic Purpura Associated With Moyamoya Syndrome in a 3-Year-Old Girl: A Case Report.
Purpura, Thrombotic Thrombocytopenic
Congenital thrombotic thrombocytopenic purpura caused by new compound heterozygous mutations of the ADAMTS13 gene.
Purpura, Thrombotic Thrombocytopenic
Correction of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes.
Purpura, Thrombotic Thrombocytopenic
Correction to: Transfusion of Platelets Loaded With Recombinant ADAMTS13 (A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13) Is Efficacious for Inhibiting Arterial Thrombosis Associated With Thrombotic Thrombocytopenic Purpura.
Purpura, Thrombotic Thrombocytopenic
Cost-effectiveness of thrombotic thrombocytopenic purpura diagnosis: a retrospective analysis in the University Hospital Center of Lyon (France).
Purpura, Thrombotic Thrombocytopenic
COVID-19 as a Potential Trigger for Immune Thrombotic Thrombocytopenic Purpura and Reason for an Unusual Treatment: A Case Report.
Purpura, Thrombotic Thrombocytopenic
Current management and therapeutical perspectives in thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Decreased ADAMTS13 activity in plasma from patients with thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Determination of anti-ADAMTS-13 autoantibody titers in ELISA: Influence of ADAMTS-13 presentation and autoantibody detection.
Purpura, Thrombotic Thrombocytopenic
Diagnosis and follow-up of thrombotic thrombocytopenic purpura with an automated chemiluminescent ADAMTS13 activity immunoassay.
Purpura, Thrombotic Thrombocytopenic
Diagnostic relevance of ADAMTS13 activity: evaluation of 28 patients with thrombotic thrombocytopenic purpura - hemolytic uremic syndrome clinical diagnosis.
Purpura, Thrombotic Thrombocytopenic
Double positivity of anti-?2-glycoprotein I domain I and anti-phosphatidylserine/prothrombin antibodies enhances both thrombosis and positivity of anti-ADAMTS13 antibody.
Purpura, Thrombotic Thrombocytopenic
Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Effect of rituximab on B cell phenotype and serum B cell-activating factor levels in patients with thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy.
Purpura, Thrombotic Thrombocytopenic
Evaluation of a New, Rapid, Fully Automated Assay for the Measurement of ADAMTS13 Activity.
Purpura, Thrombotic Thrombocytopenic
Exome Sequencing Identifies Abnormalities in Glycosylation and ANKRD36C in Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura.
Purpura, Thrombotic Thrombocytopenic
Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Genetic and Functional Characterization of ADAMTS13 Variants in a Patient Cohort with Upshaw-Schulman Syndrome Investigated in Germany.
Purpura, Thrombotic Thrombocytopenic
High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.
Purpura, Thrombotic Thrombocytopenic
Identification of a crucial tryptophan residue in ADAMTS13 required for its secretion and enzymatic activity.
Purpura, Thrombotic Thrombocytopenic
Imbalance of von Willebrand factor and ADAMTS13 axis is rather a biomarker of strong inflammation and endothelial damage than a cause of thrombotic process in critically ill COVID-19 patients.
Purpura, Thrombotic Thrombocytopenic
Incidence of obstetrical thrombotic thrombocytopenic purpura in a retrospective study within thrombocytopenic pregnant women. A difficult diagnosis and a treatable disease.
Purpura, Thrombotic Thrombocytopenic
Infection as Trigger for Congenital Thrombotic Thrombocytopenic Purpura in an Adult Patient.
Purpura, Thrombotic Thrombocytopenic
Inherited thrombotic thrombocytopenic purpura in children.
Purpura, Thrombotic Thrombocytopenic
Inherited Thrombotic Thrombocytopenic Purpura Revealed by Recurrent Strokes in a Male Adult: Case Report and Literature Review.
Purpura, Thrombotic Thrombocytopenic
Insights into ADAMTS13 structure: impact on thrombotic thrombocytopenic purpura diagnosis and management.
Purpura, Thrombotic Thrombocytopenic
N-Acetylcysteine for Relapsing Thrombotic Thrombocytopenic Purpura: More Evidence of a Promising Drug.
Purpura, Thrombotic Thrombocytopenic
Natural history of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.
Purpura, Thrombotic Thrombocytopenic
Novel Heterozygous Mutations of Congenital Thrombotic Thrombocytopenic Purpura: A Rare Case Report.
Purpura, Thrombotic Thrombocytopenic
Novel therapeutic approaches for thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
Obstetric Nephrology: AKI and Thrombotic Microangiopathies in Pregnancy.
Purpura, Thrombotic Thrombocytopenic
Plasma Levels of Big Endothelin-1 Are Associated with Renal Insufficiency and In-Hospital Mortality of Immune Thrombotic Thrombocytopenic Purpura.
Purpura, Thrombotic Thrombocytopenic
Plasmin Cleaves Von Willebrand Factor at K1491-R1492 in the A1-A2 Linker Region in a Shear- and Glycan-Dependent Manner In Vitro.
Purpura, Thrombotic Thrombocytopenic
Reduced ADAMTS13 activity in delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.
Purpura, Thrombotic Thrombocytopenic
Relapse Rate in Survivors of Acute Autoimmune Thrombotic Thrombocytopenic Purpura Treated with or without Rituximab.
Purpura, Thrombotic Thrombocytopenic
Remission of Severe, Relapsed, and Refractory TTP after Multiple Cycles of Bortezomib.
Purpura, Thrombotic Thrombocytopenic
Rituximab was effective on refractory thrombotic thrombocytopenic purpura but induced a flare of hemophagocytic syndrome in a patient with systemic lupus erythematosus.
Purpura, Thrombotic Thrombocytopenic
Rituximab-refractory thrombotic thrombocytopenic purpura responsive to intravenous but not subcutaneous bortezomib.
Purpura, Thrombotic Thrombocytopenic
Successful management of three patients with autoimmune thrombotic thrombocytopenic purpura with paradigm-changing therapy: Caplacizumab, steroids, plasma exchange, rituximab, and intravenous immunoglobulins (CASPERI).
Purpura, Thrombotic Thrombocytopenic
The ADAMTS13(1239-1253) peptide is a dominant HLA-DR1-restricted CD4+ T-cell epitope.
Purpura, Thrombotic Thrombocytopenic
The clinical utility of ADAMTS13 activity, antigen and autoantibody assays in thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
The course of ADAMTS-13 activity and inhibitor titre in the treatment of thrombotic thrombocytopenic purpura with plasma exchange and vincristine.
Purpura, Thrombotic Thrombocytopenic
The D173G mutation in ADAMTS-13 causes a severe form of congenital thrombotic thrombocytopenic purpura. A clinical, biochemical andin silico study.
Purpura, Thrombotic Thrombocytopenic
The HLA Variant rs6903608 Is Associated with Disease Onset and Relapse of Immune-Mediated Thrombotic Thrombocytopenic Purpura in Caucasians.
Purpura, Thrombotic Thrombocytopenic
The role of ADAMTS13 in the pathogenesis of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome.
Purpura, Thrombotic Thrombocytopenic
The utility of ADAMTS13 in differentiating TTP from other acute thrombotic microangiopathies: results from the UK TTP Registry.
Purpura, Thrombotic Thrombocytopenic
Thrombotic microangiopathies assessment: mind the complement.
Purpura, Thrombotic Thrombocytopenic
Thrombotic thrombocytopenic purpura during pregnancy versus imitator of preeclampsia.
Purpura, Thrombotic Thrombocytopenic
Thrombotic Thrombocytopenic Purpura Masquerading as Acute Ischemic Stroke.
Purpura, Thrombotic Thrombocytopenic
Thrombotic thrombocytopenic purpura related to severe ADAMTS13 deficiency in children.
Purpura, Thrombotic Thrombocytopenic
Thrombotic Thrombocytopenic Purpura: Beyond Empiricism and Plasma Exchange.
Purpura, Thrombotic Thrombocytopenic
Transfusion of Platelets Loaded With Recombinant ADAMTS13 (A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13) Is Efficacious for Inhibiting Arterial Thrombosis Associated With Thrombotic Thrombocytopenic Purpura.
Purpura, Thrombotic Thrombocytopenic
Unresponsive Thrombotic Thrombocytopenic Purpura (TTP): Challenges and Solutions.
Purpura, Thrombotic Thrombocytopenic
Untying the knot of thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome.
Purpura, Thrombotic Thrombocytopenic
Upshaw-Schulman Syndrome With c.2728C>T Mutation in ADAMTS13 Gene.
Purpura, Thrombotic Thrombocytopenic
Von Willebrand factor, ADAMTS-13, and thrombotic thrombocytopenic purpura.
Purpura, Thrombotic Thrombocytopenic
VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP.
Purpura, Thrombotic Thrombocytopenic
What's new in the diagnosis and pathophysiology of thrombotic thrombocytopenic purpura.
receptor protein-tyrosine kinase deficiency
Loss of Fgfr1 in chondrocytes inhibits osteoarthritis by promoting autophagic activity in temporomandibular joint.
Renal Insufficiency
Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy.
Renal Insufficiency
What's new in the diagnosis and pathophysiology of thrombotic thrombocytopenic purpura.
Renal Insufficiency, Chronic
A Disintegrin and Metalloenzyme (ADAM) 17 Activation Is Regulated by ?5?1 Integrin in Kidney Mesangial Cells.
Renal Insufficiency, Chronic
Circulating ADAMs are associated with renal and cardiovascular outcomes in chronic kidney disease patients.
Renal Insufficiency, Chronic
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Renal Insufficiency, Chronic
The epidermal growth factor receptor pathway in chronic kidney diseases.
Reoviridae Infections
A functional role for ADAM10 in human immunodeficiency virus type-1 replication.
Reperfusion Injury
Trimucrin, an Arg-Gly-Asp containing disintegrin, attenuates myocardial ischemia-reperfusion injury in murine by inhibiting platelet function.
Respiratory Hypersensitivity
ADAM metallopeptidase domain 33 (ADAM33): identification and role in airways disease.
Retinal Neovascularization
Characterization of the Catalytic Properties of the Membrane-anchored Metalloprotease ADAM9 in Cell-based assays.
Rhabdomyosarcoma, Embryonal
A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.
Rhinitis
Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population.
Rhinitis, Allergic
ADAM33 polymorphisms and susceptibility to allergic rhinitis: a meta-analysis.
Rhinitis, Allergic
Association between ADAM33 S2 and V4 polymorphisms and susceptibility to allergic rhinitis: A meta-analysis.
Rhinitis, Allergic
Increased expression of a disintegrin and metalloprotease 8 in allergic rhinitis.
Sarcoidosis, Pulmonary
A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis.
Sarcoidosis, Pulmonary
Serum concentrations of A disintegrin and metalloproteinase 9 (ADAM9) mRNA as a promising novel marker for the detection of pulmonary sarcoidosis.
Sarcoma
The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model.
Sarcoma
The effect of microRNA-330 replacement on inhibition of growth and migration in renal cancer cells.
Sepsis
MicroRNA-147b regulates vascular endothelial barrier function by targeting ADAM15 expression.
Sepsis
miR-23b Negatively Regulates Sepsis-Induced Inflammatory Responses by Targeting ADAM10 in Human THP-1 Monocytes.
Sepsis
Preserved Expression of mRNA Coding von Willebrand Factor-Cleaving Protease ADAMTS13 by Selenite and Activated Protein C.
Sepsis
Snake Venom Disintegrin Inhibits the Activation of Toll-Like Receptors and Alleviates Sepsis through Integrin alphaVbeta3 Blockade.
Sepsis
The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulation.
Sepsis
Three Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.
Severe Acute Respiratory Syndrome
ACE2 (Angiotensin-Converting Enzyme 2) in Cardiopulmonary Diseases: Ramifications for the Control of SARS-CoV-2.
Shock, Septic
Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome.
Shock, Septic
The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulation.
Skin Diseases
A disintegrin and metalloprotease (ADAM) 33 protein in patients with pulmonary sarcoidosis.
Spinal Cord Injuries
Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke.
Squamous Cell Carcinoma of Head and Neck
ADAM17-mediated CD44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC.
Squamous Cell Carcinoma of Head and Neck
Expression of "a disintegrin and metalloproteinase-33" (ADAM-33) protein in laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Involvement of NF-kappaB-mediated maturation of ADAM-17 in the invasion of oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Overexpression of A disintegrin and metalloprotease 10 promotes tumor proliferation, migration and poor prognosis in hypopharyngeal squamous cell carcinoma.
Stomach Neoplasms
A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer.
Stomach Neoplasms
Downregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer.
Stomach Neoplasms
Identified a disintegrin and metalloproteinase with thrombospondin motifs 6 serve as a novel gastric cancer prognostic biomarker by bioinformatics analysis.
Stomach Neoplasms
Prognostic Significance of ADAM17 for Gastric Cancer Survival: A Meta-Analysis.
Stomach Neoplasms
The effect of disintegrin-metalloproteinase ADAM9 in gastric cancer progression.
Stomach Neoplasms
Upregulated Expression of ADAM17 Is a Prognostic Marker for Patients With Gastric Cancer.
Stomach Neoplasms
Upregulation of a disintegrin and metalloprotease 8 is associated with progression and prognosis of patients with gastric cancer.
Stroke
ADAMTS13 maintains cerebrovascular integrity to ameliorate Alzheimer-like pathology.
Stroke
Recombinant ADAMTS13 reduces tissue plasminogen activator-induced hemorrhage after stroke in mice.
Thrombocytopenia
A Difficult Diagnosis Case of Prolonged Thrombocytopenia With Sepsis and Disseminated Intravascular Coagulation.
Thrombocytopenia
Caplacizumab to treat immune-mediated thrombotic thrombocytopenic purpura.
Thrombocytopenia
Congenital thrombotic thrombocytopenic purpura presenting in adulthood with recurrent cerebrovascular events.
Thrombocytopenia
Current management and therapeutical perspectives in thrombotic thrombocytopenic purpura.
Thrombocytopenia
Emerging roles of adjunct therapies in acquired thrombotic thrombocytopenia purpura.
Thrombocytopenia
From Discovery of Snake Venom Disintegrins to A Safer Therapeutic Antithrombotic Agent.
Thrombocytopenia
Incidence of obstetrical thrombotic thrombocytopenic purpura in a retrospective study within thrombocytopenic pregnant women. A difficult diagnosis and a treatable disease.
Thrombocytopenia
Infection as Trigger for Congenital Thrombotic Thrombocytopenic Purpura in an Adult Patient.
Thrombocytopenia
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Thrombocytopenia
Limitations of ADAMTS-13 Activity Level in Diagnosing Thrombotic Thrombocytopenic Purpura in Pregnancy.
Thrombocytopenia
Relapse Rate in Survivors of Acute Autoimmune Thrombotic Thrombocytopenic Purpura Treated with or without Rituximab.
Thrombocytopenia
Secondary thrombotic microangiopathy with severely reduced ADAMTS13 activity in a patient with Capnocytophaga canimorsus sepsis: a case report.
Thrombocytopenia
Three Hypothetical Inflammation Pathobiology Phenotypes and Pediatric Sepsis-Induced Multiple Organ Failure Outcome.
Thrombocytopenia
What's new in the diagnosis and pathophysiology of thrombotic thrombocytopenic purpura.
Thrombosis
ADAMTS13 ameliorates inflammatory responses in experimental autoimmune encephalomyelitis.
Thrombosis
ADAMTS13 Retards Progression of Diabetic Nephropathy by Inhibiting Intrarenal Thrombosis in Mice.
Thrombosis
Assessment of the Diagnostic Value of Plasma Levels, Activities, and Their Ratios of von Willebrand Factor and ADAMTS13 in Patients with Cerebral Infarction.
Thrombosis
Balance between von Willebrand factor and ADAMTS13 following major partial hepatectomy.
Thrombosis
Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor string formation under flow in a free-thiol-dependent manner.
Thrombosis
cDNA cloning of a snake venom metalloproteinase from the eastern diamondback rattlesnake (Crotalus adamanteus), and the expression of its disintegrin domain with anti-platelet effects.
Thrombosis
Coagulopathy and Thrombosis as a Result of Severe COVID-19 Infection: A Microvascular Focus.
Thrombosis
Congenital ADAMTS-13 deficiency presenting as life-threatening thrombosis during pregnancy.
Thrombosis
Correction to: Transfusion of Platelets Loaded With Recombinant ADAMTS13 (A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13) Is Efficacious for Inhibiting Arterial Thrombosis Associated With Thrombotic Thrombocytopenic Purpura.
Thrombosis
Effect of recombinant ADAMTS13 on microthrombosis and brain injury after experimental subarachnoid hemorrhage.
Thrombosis
Evaluation of the disintegrin, triflavin, in a rat middle cerebral artery thrombosis model.
Thrombosis
Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease.
Thrombosis
Formation and Resolution of Pial Microvascular Thrombosis in a Mouse Model of Thrombotic Thrombocytopenic Purpura.
Thrombosis
Genetic ablation of Adamts13 gene dramatically accelerates the formation of early atherosclerosis in a murine model.
Thrombosis
Increased dipeptidyl peptidase-4 accelerates chronic stress-related thrombosis in a mouse carotid artery model.
Thrombosis
Plasma von Willebrand Factor and a Disintegrin and Metalloproteinase with Eight Thrombospondin-type 1 Motif Levels in Hemodialysis Patients: Relation to Vascular Access Thrombosis.
Thrombosis
Selectivity of the collagen-binding integrin inhibitors, TC-I-15 and obtustatin.
Thrombosis
Synergistic effect of aurintricarboxylic acid and triflavin in a photochemically induced thrombosis model in rats.
Thrombosis
Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice.
Thrombosis
Transfusion of Platelets Loaded With Recombinant ADAMTS13 (A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13) Is Efficacious for Inhibiting Arterial Thrombosis Associated With Thrombotic Thrombocytopenic Purpura.
Thrombosis
Vascular thrombus imaging in vivo via near-infrared fluorescent nanodiamond particles bioengineered with the disintegrin bitistatin (Part II).
Thrombosis
[Stable expression and characterization of the von Willebrand factor cleaving protease]
Thrombotic Microangiopathies
A Case of Recurrent Thrombotic Microangiopathy Caused by Hypertensive Urgency.
Thrombotic Microangiopathies
A human monoclonal antibody against the distal carboxyl terminus of ADAMTS-13 modulates its susceptibility to an inhibitor in thrombotic thrombocytopenic purpura.
Thrombotic Microangiopathies
A new mouse model mimicking thrombotic thrombocytopenic purpura: correction of symptoms by recombinant human ADAMTS13.
Thrombotic Microangiopathies
ADAMTS13 related markers and von Willebrand factor in plasma from patients with thrombotic microangiopathy (TMA).
Thrombotic Microangiopathies
Attending rounds: microangiopathic hemolytic anemia with renal insufficiency.
Thrombotic Microangiopathies
Autoimmune thrombotic microangiopathy: advances in pathogenesis, diagnosis, and management.
Thrombotic Microangiopathies
Chest pain with increased troponin level; not always a cardiology issue.
Thrombotic Microangiopathies
Child-onset and adolescent-onset acquired thrombotic thrombocytopenic purpura with severe ADAMTS13 deficiency: a cohort study of the French national registry for thrombotic microangiopathy.
Thrombotic Microangiopathies
Clinical features and outcomes in patients with thrombotic microangiopathy not associated with severe ADAMTS13 deficiency.
Thrombotic Microangiopathies
Comparison of Rituximab originator (MabThera) to biosimilar (Truxima) in patients with immune-mediated thrombotic thrombocytopenic purpura.
Thrombotic Microangiopathies
Congenital thrombotic thrombocytopenic purpura caused by new compound heterozygous mutations of the ADAMTS13 gene.
Thrombotic Microangiopathies
Current management and therapeutical perspectives in thrombotic thrombocytopenic purpura.
Thrombotic Microangiopathies
Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report.
Thrombotic Microangiopathies
Diagnosis and follow-up of thrombotic thrombocytopenic purpura with an automated chemiluminescent ADAMTS13 activity immunoassay.
Thrombotic Microangiopathies
Donor Age Affects Liver Regeneration during Early Period in the Graft Liver and Late Period in the Remnant Liver after Living Donor Liver Transplantation.
Thrombotic Microangiopathies
Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy.
Thrombotic Microangiopathies
Evaluation of a New, Rapid, Fully Automated Assay for the Measurement of ADAMTS13 Activity.
Thrombotic Microangiopathies
Influenza-associated thrombotic microangiopathy with unbalanced von Willebrand factor and a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 levels in a heterozygous protein S-deficient boy.
Thrombotic Microangiopathies
Inherited Thrombotic Thrombocytopenic Purpura Revealed by Recurrent Strokes in a Male Adult: Case Report and Literature Review.
Thrombotic Microangiopathies
Intensive plasma exchange increases a disintegrin and metalloprotease with thrombospondin motifs-13 activity and reverses organ dysfunction in children with thrombocytopenia-associated multiple organ failure.
Thrombotic Microangiopathies
Intensive plasma exchange increases ADAMTS-13 activity and reverses organ dysfunction in children with thrombocytopenia-associated multiple organ failure.
Thrombotic Microangiopathies
Natural history of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.
Thrombotic Microangiopathies
Novel therapeutic approaches for thrombotic thrombocytopenic purpura.
Thrombotic Microangiopathies
Obstetric Nephrology: AKI and Thrombotic Microangiopathies in Pregnancy.
Thrombotic Microangiopathies
Pathophysiology of Pediatric Multiple Organ Dysfunction Syndrome.
Thrombotic Microangiopathies
Performance of Diagnostic Scores in Thrombotic Microangiopathy Patients in the Intensive Care Unit: A Monocentric Study.
Thrombotic Microangiopathies
Preserved Expression of mRNA Coding von Willebrand Factor-Cleaving Protease ADAMTS13 by Selenite and Activated Protein C.
Thrombotic Microangiopathies
The D173G mutation in ADAMTS-13 causes a severe form of congenital thrombotic thrombocytopenic purpura. A clinical, biochemical andin silico study.
Thrombotic Microangiopathies
The HLA Variant rs6903608 Is Associated with Disease Onset and Relapse of Immune-Mediated Thrombotic Thrombocytopenic Purpura in Caucasians.
Thrombotic Microangiopathies
The utility of ADAMTS13 in differentiating TTP from other acute thrombotic microangiopathies: results from the UK TTP Registry.
Thrombotic Microangiopathies
Thrombotic microangiopathy due to malignant hypertension complicated with late-onset bleeding after renal biopsy.
Thrombotic Microangiopathies
Unresponsive Thrombotic Thrombocytopenic Purpura (TTP): Challenges and Solutions.
Triple Negative Breast Neoplasms
miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells.
Triple Negative Breast Neoplasms
N-glycosylation regulates ADAM8 processing and activation.
Tuberculosis
Serum concentrations of A disintegrin and metalloproteinase 9 (ADAM9) mRNA as a promising novel marker for the detection of pulmonary sarcoidosis.
Tuberculosis, Spinal
Correlation analysis of ADAMTS-4, VCAM-1, and TAK1 expression in cartilage tissue from spine tuberculosis.
Ureteral Obstruction
Expression and significance of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-1 in an animal model of renal interstitial fibrosis induced by unilateral ureteral obstruction.
Urinary Bladder Neoplasms
Expression and Clinical Significance of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and a Disintegrin and Metalloproteinase with Thrombospondin Type 1 Motif 1 (ADAMTS1) in Post-Kidney-Transplant Bladder Tumors.
Urinary Bladder Neoplasms
The microRNA miR-3174 Suppresses the Expression of ADAM15 and Inhibits the Proliferation of Patient-Derived Bladder Cancer Cells.
Urogenital Neoplasms
Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.
Uveitis
The disintegrin domain of ADAM 8 enhances protection against rat experimental autoimmune encephalomyelitis, neuritis and uveitis by a polyvalent autoantigen vaccine.
Vascular Diseases
A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection.
Vascular Diseases
ADAMTS-5 Decreases in Aortas and Plasma From Aortic Dissection Patients and Alleviates Angiotensin II-Induced Smooth Muscle-Cell Apoptosis.
Vascular Diseases
Adamts18 modulates the development of the aortic arch and common carotid artery.
Vascular Diseases
Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.
Vascular Diseases
High-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation.
Vascular Diseases
The Antiatherogenic Effect of Fish Oil in Male Mice Is Associated with a Diminished Release of Endothelial ADAM17 and ADAM10 Substrates.
Vascular System Injuries
Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease.
Vasculitis
Hypertensive emergency presenting with diffuse alveolar hemorrhaging and thrombotic microangiopathy: A case report and review of the literature.
Virus Diseases
A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection.
Virus Diseases
ADAM10 Partially Protects Mice against Influenza Pneumonia by Suppressing Specific Myeloid Cell Population.
Virus Diseases
Interferon induced thrombotic microangiopathy (TMA): Analysis and concise review.
Vitamin B 12 Deficiency
Atypical hemolytic uremic syndrome and complement blockade: established and emerging uses of complement inhibition.
von Willebrand Disease, Type 1
An amino acid polymorphism in von Willebrand factor correlates with increased susceptibility to proteolysis by ADAMTS13.
von Willebrand Diseases
An amino acid polymorphism in von Willebrand factor correlates with increased susceptibility to proteolysis by ADAMTS13.
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