Reference on EC 3.4.23.20 - Penicillopepsin
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Emi, S.; Myers, D.V.; Iacobucci, G.A.
Purification and properties of the thermostable acid protease of Penicillium duponti
Biochemistry
15
842-848
1976
Penicillium duponti, Penicillium duponti K 1014
Hsu, I.N.; Delbaere, L.T.J.; James, M.N.G.
Penicillopepsin from Penicillium janthinellum crystal structure at 2.8 A and sequence homology with porcine pepsin
Nature
266
140-145
1977
Penicillium janthinellum
Hofmann, T.; Allen, B.; Bendiner, M.; Blum, M.; Cunningham, A.
Effect of secondary substrate binding in penicillopepsin: contributions of subsites S3 and S2 to kcat
Biochemistry
27
1140-1146
1988
Penicillium janthinellum
Dunn, B.M.; Jimenez, M.; Parten, B.F.; Valler, M.J.; Rolph, C.E.; Kay, J.
A systematic series of synthetic chromophoric substrates for aspartic proteinases
Biochem. J.
237
899-906
1986
Penicillium janthinellum
James, M.N.G.; Hsu, I.N.; Delbaere, L.T.J.
Mechanism of acid protease catalysis based on the crystal structure of penicillopepsin
Nature
267
808-813
1977
Penicillium janthinellum
Mains, G.; Hofmann, T.
The inactivation of penicillopepsin with 1,2-epoxy-3-(p-nitrophenoxy) propane, an active-site directed reagent
Can. J. Biochem.
52
1018-1023
1974
Penicillium janthinellum
Wang, T.T.; Hofmann, T.
Acyl and amino intermediates in penicillopepsin-catalysed reactions and activation by nonsubstrate peptides
Can. J. Biochem.
55
286-294
1977
Penicillium janthinellum
Hsu, I.N.; Hofman, T.; Nyburg, S.C.
The crystal structure of penicillopesin at 6 A resolution
Biochem. Biophys. Res. Commun.
72
363-368
1976
Penicillium janthinellum
Mabrouk, S.S.; Amr, A.S.; Abdel-Fattah, A.F.
A rennin-like enzyme from Penicillium expansum
Agric. Biol. Chem.
40
419-420
1976
Penicillium expansum
-
Hashimoto, H.; Iwaasa, T.; Yokotsuka, T.
Some properties of acid protease from the thermophilic fungus, Penicillium duponti K1014
Appl. Microbiol.
25
578-583
1973
Penicillium duponti, Penicillium duponti K 1014
Hashimoto, H.; Kaneko, Y.; Iwaasa, T.; Yokotsuka, T.
Production and purification of acid protease from the thermophilic fungus, Penicillium duponti K1014
Appl. Microbiol.
25
584-588
1973
Penicillium duponti, Penicillium duponti K 1014
Blum, M.; Cunningham, A.; Bendiner, M.; Hofmann, T.
Penicillopepsin, the aspartic proteinase from Penicillium janthinellum: substrate-binding effects and intermediates in transpeptidation reactions
Biochem. Soc. Trans.
13
1044-1046
1985
Penicillium janthinellum
James, M.N.G.; Sielecki, A.R.
Stereochemical analysis of peptide bond hydrolysis catalyzed by the aspartic proteinase penicillopepsin
Biochemistry
24
3701-3713
1985
Penicillium janthinellum
Hofmann, T.; Hodges, R.S.; James, M.N.G.
Effect of pH on the activities of penicillopepsin and Rhizopus pepsin and a proposal for the productive substrate binding mode in penicillopepsin
Biochemistry
23
635-643
1984
Penicillium janthinellum
James, M.N.G.; Sielecki, A.R.
Structure and refinement of penicillopepsin at 1.8 A resolution
J. Mol. Biol.
163
299-361
1983
Penicillium janthinellum
James, M.N.G.; Sielecki, A.R.; Hayakawa, K.; Gelb, M.H.
Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides
Biochemistry
31
3872-3886
1992
Penicillium janthinellum
Fraser, M.E.; Strynadka, N.C.J.; Bartlett, P.A.; Hanson, J.E.; James, M.N.G.
Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues
Biochemistry
31
5201-5214
1992
Penicillium janthinellum
Houmard, J.; Raymond, M.N.
Further characterization of the Penicillium roqueforti acid protease
Biochimie
61
979-982
1979
Penicillium roqueforti
Gripon, J.C.
Inactivation of Penicillium roqueforti acid protease by specific pepsin inhibitors
Biochimie
58
747-749
1976
Penicillium roqueforti
Fraser, M.E.; Meyer, J.H.; Bartlett, P.A.; James, M.N.
Overcoming the unfavourable entropic contribution of ligand binding with a macrocyclic inhibitor bound to penicillopepsin
Adv. Exp. Med. Biol.
436
355-359
1998
Penicillium sp.
Khan, A.R.; Parrish, J.C.; Fraser, M.E.; Smith, W.W.; Bartlett, P.A.; James, M.N.G.
Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes
Biochemistry
37
16839-16845
1998
Penicillium janthinellum (P00798)
Cao, Q.N.; Stubbs, M.; Ngo, K.Q.; Ward, M.; Cunningham, A.; Pai, E.F.; Tu, G.C.; Hofmann, T.
Penicillopepsin-JT2, a recombinant enzyme from Penicillium janthinellum and the contribution of a hydrogen bond in subsite S3 to k(cat)
Protein Sci.
9
991-1001
2000
Penicillium janthinellum, Penicillium janthinellum NRRL 905
Hofmann, T.
Penicillopepsin
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds. )
1
99-104
2004
Penicillium camemberti, Penicillium duponti, Penicillium janthinellum, Penicillium janthinellum (P78735), Penicillium janthinellum (Q9HEZ3), Penicillium roqueforti, Penicillium duponti K1014
-
Vidossich, P.; Carloni, P.
Binding of phosphinate and phosphonate inhibitors to aspartic proteases: a first-principles study
J. Phys. Chem. B
110
1437-1442
2006
Penicillium janthinellum
Smirnova, I.; Sereda, A.; Kostyleva, E.; Tsurikova, N.; Bushina, E.; Rozhkova, A.; Sinitsyn, A.
A new enzyme preparation with high penicillopepsin activity based on the producer strain Penicillium canescens
Appl. Biochem. Microbiol.
51
660-666
2015
Penicillium canescens, Penicillium canescens RN3-11-7 niaD(-)
Alhelli, A.; Manap, M.; Mohammed, A.; Mirhosseini, H.; Suliman, E.; Shad, Z.; Mohammed, N.; Hussin, A.
Response surface methodology modelling of an aqueous two-phase system for purification of protease from Penicillium candidum (PCA 1/TT031) under solid state fermentation and its biochemical characterization
Int. J. Mol. Sci.
17
1872
2016
Penicillium candidum, Penicillium candidum PCA 1/TT031
Suarez, D.; Diaz, N.
Ligand strain and entropic effects on the binding of macrocyclic and linear inhibitors molecular modeling of penicillopepsin complexes
J. Chem. Inf. Model.
57
2045-2055
2017
Penicillium janthinellum (P00798)
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