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Information on EC 3.4.22.B35 - calpain 15 and Organism(s) Homo sapiens and UniProt Accession O75808

for references in articles please use BRENDA:EC3.4.22.B35
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B35 calpain 15
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This record set is specific for:
Homo sapiens
UNIPROT: O75808
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The taxonomic range for the selected organisms is: Homo sapiens
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
broad endopeptidase specificity
Synonyms
capn15, sol calpain, calpain 15, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
small optic lobes protein
-
-
-
-
CAS REGISTRY NUMBER
COMMENTARY hide
78990-62-2
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CAN15_HUMAN
1086
0
117314
Swiss-Prot
-
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
medicine
biomarkers proposed for stroke diagnosis include tissue leakage metalloproteins such as calpain-15, titin (isoform 3), and tropomyosin alpha-4 chain. Metalloproteins, such as selenoprotein P or glutathione peroxidase, are identified in all stroke type groups
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nahan, K.S.; Walsh, K.B.; Adeoye, O.; Landero-Figueroa, J.A.
The metal and metalloprotein profile of human plasma as biomarkers for stroke diagnosis
J. Trace Elem. Med. Biol.
42
81-91
2017
Homo sapiens (O75808)
Manually annotated by BRENDA team