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Disease on EC 3.4.22.B30 - calpain 10

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acne Vulgaris
Calpain 10 gene single-nucleotide 44 polymorphism may have an influence on clinical and metabolic features in patients with polycystic ovary syndrome.
Atherosclerosis
Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study.
Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.
Replication of calpain-10 genetic association with carotid intima-media thickness.
SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study.
Carcinoma
Identification of a protective haplogenotype within CAPN10 gene influencing colorectal cancer susceptibility.
Oncogene GAEC1 regulates CAPN10 expression which predicts survival in esophageal squamous cell carcinoma.
Cardiovascular Diseases
Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels.
The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population.
Cataract
Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization.
Role of calpains in diabetes mellitus-induced cataractogenesis: a mini review.
Cerebral Small Vessel Diseases
The SNP43 (G/A) polymorphism in CAPN10 gene confers an increased risk of cognitive impairment in cerebral small vessel disease.
Colorectal Neoplasms
Calpain-10 SNP43 and SNP19 polymorphisms and colorectal cancer: a matched case-control study.
Identification of a protective haplogenotype within CAPN10 gene influencing colorectal cancer susceptibility.
Coronary Artery Disease
Association between type 2 diabetes mellitus, biochemical factors and UCSNP-43 polymorphisms of CALPIN-10 gene in patients with atherosclerosis of coronary artery disease in Southern Iran population.
Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study.
Cystic Fibrosis
Calpain 10 and development of diabetes mellitus in cystic fibrosis.
Diabetes Mellitus
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.
A case-control study on the association of common variants of CAPN10 gene and the risk of type 2 diabetes in an Iranian population.
A novel 111/121 diplotype in the Calpain-10 gene is associated with type 2 diabetes.
Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decreased risk of diabetic retinopathy in type 2 diabetes.
Analysis of the structure of calpain-10 and its interaction with the protease inhibitor SNJ-1715.
Association of calpain 10 gene polymorphisms with type 2 diabetes mellitus in Southern Indians.
Association of calpain-10 gene polymorphism and posttransplant diabetes mellitus in kidney transplant patients medicated with tacrolimus.
Association of calpain-10 rs2975760 polymorphism with type 2 diabetes mellitus: a meta-analysis.
Association of IRS1, CAPN10, and PPARG gene polymorphisms with type 2 diabetes mellitus in the high-risk population of Hyderabad, India.
Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population.
Calpain 10 and development of diabetes mellitus in cystic fibrosis.
Calpain 10 SNP-44 gene polymorphism affects susceptibility to type 2 diabetes mellitus and diabetic-related conditions.
Calpain-10 and Adiponectin Gene Polymorphisms in Korean Type 2 Diabetes Patients.
Calpain-10 gene polymorphism in type 2 diabetes mellitus patients in the Gaza Strip.
Calpain-10 gene polymorphisms and risk of type 2 diabetes mellitus in Mexican mestizos.
Calpain-10 gene polymorphisms and type 2 diabetes in West Africans: the Africa America Diabetes Mellitus (AADM) Study.
Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B.
CAPN10 alleles modify laryngeal cancer risk in the Spanish population.
CAPN10 SNP43 G>A gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 9353 participants.
Capn10, a candidate gene responsible for type 2 diabetes mellitus in the OLETF rat.
Characterization and expression of calpain 10. A novel ubiquitous calpain with nuclear localization.
Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal women.
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Haplotype association of calpain 10 gene variants with type 2 diabetes mellitus in an Irish sample.
Homozygous combination of calpain 10 gene haplotypes is associated with type 2 diabetes mellitus in a Polish population.
Investigation of glucocorticoid receptor and calpain-10 gene polymorphisms in Turkish patients with type 2 diabetes mellitus
Polymorphism in the Calpain 10 gene influences glucose metabolism in human fat cells.
Role of Calpain-10 in the Development of Diabetes Mellitus and Its Complications.
Single Nucleotide Polymorphisms Associated with Metformin and Sulphonylureas' Glycaemic Response among South African Adults with Type 2 Diabetes Mellitus.
Single nucleotide polymorphisms in CAPN10 gene of Chinese people and its correlation with type 2 diabetes mellitus in Han people of northern China.
Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
The effect of calpain-10 gene polymorphism on the development of type 2 diabetes mellitus in a Turkish population.
The reduction of Calpain-10 expression is associated with risk polymorphisms in obese children.
Type 2 diabetes candidate gene CAPN10: first, but not last.
Variants of calpain-10 gene and its association with type 2 diabetes mellitus in a Chinese population.
Variation in the calpain-10 gene is not associated with gestational diabetes mellitus.
Variations in the calpain-10 gene are associated with the risk of type 2 diabetes and hypertension in northern Han Chinese population.
[Association analysis of SNP-63 and indel-19 variant in the calpain-10 gene with polycystic ovary syndrome in women of reproductive age].
[Association between calpain-10 gene polymorphism and risk of type 2 diabetes mellitus: a meta analysis]
[Association of the calpain-10 gene polymorphism with glucose metabolism disorder in pregnant women]
[Single nucleotide polymorphisms in CAPN10 gene of Chinese population and its correlation with type 2 diabetes mellitus in Han people of northern China]
[SNP-19 genotypic variants of CAPN10 gene and its relation to diabetes mellitus type 2 in a population of Ciudad Juarez, Mexico].
[The impact of calpain-10 gene combined-SNP variation on type 2 diabetes mellitus and its related metabolic traits]
[The UCSNP44 variation of calpain 10 gene on NIDDM1 locus and its impact on plasma glucose levels in type 2 diabetic patients]
Diabetes Mellitus, Type 2
A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.
A case-control study on the association of common variants of CAPN10 gene and the risk of type 2 diabetes in an Iranian population.
A genetic variant of the CAPN10 gene in Mexican subjects with dyslipidemia is associated with increased HDL-cholesterol concentrations after the consumption of a soy protein and soluble fiber dietary portfolio.
A novel 111/121 diplotype in the Calpain-10 gene is associated with type 2 diabetes.
A pharmacogenetic association between a variation in calpain 10 (CAPN10) gene and the response to metformin treatment in patients with type 2 diabetes.
A Replication Study of the IRS1, CAPN10, TCF7L2, and PPARG Gene Polymorphisms Associated with Type 2 Diabetes in Two Different Populations of Mexico.
Absence of association of type 2 diabetes with CAPN10 and PC-1 polymorphisms in Oji-Cree.
Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decreased risk of diabetic retinopathy in type 2 diabetes.
Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies.
Assessing optimal neural network architecture for identifying disease-associated multi-marker genotypes using a permutation test, and application to calpain 10 polymorphisms associated with diabetes.
Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies.
Association of calpain 10 gene polymorphisms with type 2 diabetes mellitus in Southern Indians.
Association of calpain-10 polymorphisms with type 2 diabetes in the Tunisian population.
Association of calpain-10 rs2975760 polymorphism with type 2 diabetes mellitus: a meta-analysis.
Association of IRS1, CAPN10, and PPARG gene polymorphisms with type 2 diabetes mellitus in the high-risk population of Hyderabad, India.
Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses.
Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population.
Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study.
Association of the SNP-19 genotype 22 in the calpain-10 gene with elevated body mass index and hemoglobin A1c levels in Japanese.
Association of two synonymous splicing-associated CpG single nucleotide polymorphisms in calpain 10 and solute carrier family 2 member 2 with type 2 diabetes.
Calpain 10 and genetics of type 2 diabetes.
Calpain 10 and type 2 diabetes: are we getting closer to an explanation?
Calpain 10 as a predictive gene for type 2 diabetes: evidence from a novel screening system using white blood cells of Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
Calpain 10 gene polymorphisms are related, not to type 2 diabetes, but to increased serum cholesterol in Japanese.
Calpain 10 Homology Modeling with CYGAK and Increased Lipophilicity Leads to Greater Potency and Efficacy in Cells.
Calpain 10 SNP-44 gene polymorphism affects susceptibility to type 2 diabetes mellitus and diabetic-related conditions.
Calpain Activity in Leukocytes Is Associated with Diabetes Biochemical Markers.
Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in adipocytes.
Calpain inhibition and insulin action in cultured human muscle cells.
Calpain inhibition impairs glycogen syntheses in HepG2 hepatoma cells without altering insulin signaling.
Calpain-10 (NIDDM1) as a Susceptibility Gene for Common Type 2 Diabetes.
Calpain-10 and Adiponectin Gene Polymorphisms in Korean Type 2 Diabetes Patients.
Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes.
Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes.
Calpain-10 gene polymorphism in type 2 diabetes mellitus patients in the Gaza Strip.
Calpain-10 gene polymorphism is associated with reduced beta(3)-adrenoceptor function in human fat cells.
Calpain-10 gene polymorphisms and risk of type 2 diabetes mellitus in Mexican mestizos.
Calpain-10 gene polymorphisms and type 2 diabetes in West Africans: the Africa America Diabetes Mellitus (AADM) Study.
Calpain-10 gene polymorphisms in type 2 diabetes and its micro- and macrovascular complications.
Calpain-10 haplotype combination and association with gestational diabetes mellitus.
Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome.
Calpain-10 is a component of the obesity-related quantitative trait locus Adip1.
Calpain-10 is a component of the obesity-related quantitative trait locus, Adip1.
Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B.
Calpain-10: from genome search to function.
Calpain: a death protein that mediates progression of liver injury.
Calpains and human disease.
Calpains play a role in insulin secretion and action.
CAPN10 alleles modify laryngeal cancer risk in the Spanish population.
CAPN10 mRNA splicing and decay is not affected by a SNP associated with susceptibility to type 2 diabetes.
CAPN10 SNP43 G>A gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 9353 participants.
Capn10, a candidate gene responsible for type 2 diabetes mellitus in the OLETF rat.
Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: examples from studies of the calpain-10 gene.
Challenges in studies of the genetic basis of Type 2 diabetes.
Characterization of endogenous and recombinant human calpain-10.
Characterization of GLUT4 and calpain expression in healthy human skeletal muscle during fasting and refeeding.
Chronic high glucose downregulates mitochondrial calpain 10 and contributes to renal cell death and diabetes-induced renal injury.
Co-existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population.
Combining sperm typing and linkage disequilibrium analyses reveals differences in selective pressures or recombination rates across human populations.
Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal women.
Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study.
Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes.
Ethnic differences in CAPN10 SNP-19 in type 2 diabetes: a North-West Indian case control study and evidence from meta-analysis.
Evidence that an isoform of calpain-10 is a regulator of exocytosis in pancreatic beta-cells.
Functional significance of the UCSNP-43 polymorphism in the CAPN10 gene for proinsulin processing and insulin secretion in nondiabetic Germans.
Genetic and nongenetic regulation of CAPN10 mRNA expression in skeletal muscle.
Genetic determinants of type 2 diabetes mellitus.
Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population.
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese.
Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus.
GLUT4 expression in 3T3-L1 adipocytes is repressed by proteasome inhibition, but not by inhibition of calpains.
GSTT1, Calpain 10 SNP 19 and indices of glycaemia in type 2 diabetes.
Haplotype association of calpain 10 gene variants with type 2 diabetes mellitus in an Irish sample.
Haplotype combination of Calpain-10 gene polymorphism is associated with metabolic syndrome in type 2 diabetes.
Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians.
Haplotype structure and phylogenetic shadowing of a hypervariable region in the CAPN10 gene.
Homozygous combination of calpain 10 gene haplotypes is associated with type 2 diabetes mellitus in a Polish population.
Identification of copy number variation of CAPN10 in Thais with type 2 diabetes by multiplex PCR and denaturing high performance liquid chromatography (DHPLC).
Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic ?-cells.
Investigation of glucocorticoid receptor and calpain-10 gene polymorphisms in Turkish patients with type 2 diabetes mellitus
LightCycler assay in the analysis of haplotypes of the type 2 diabetes susceptibility gene CAPN10.
Linkage but not association of calpain-10 to type 2 diabetes replicated in northern sweden.
Linkage of calpain 10 to type 2 diabetes: the biological rationale.
Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility.
Molecular signatures of Calpain 10 isoforms sequences, envisage functional similarity and therapeutic potential.
New evidence for the role of calpain 10 in autosomal recessive intellectual disability: identification of two novel nonsense variants by exome sequencing in Iranian families.
No evidence for involvement of the calpain-10 gene 'high-risk' haplotype combination for non-insulin-dependent diabetes mellitus in early onset obesity.
Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes.
Patterns of linkage disequilibrium in the type 2 diabetes gene calpain-10.
Population genetics of CAPN10 and GPR35: implications for the evolution of type 2 diabetes variants.
Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification.
Relationship between calpain-10 gene polymorphism and insulin resistance phenotypes in Chinese.
Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians.
Role of Calpain-10 in the Development of Diabetes Mellitus and Its Complications.
RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.
Searching for genes in diabetes and the metabolic syndrome.
Single nucleotide polymorphisms in CAPN10 gene of Chinese people and its correlation with type 2 diabetes mellitus in Han people of northern China.
SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study.
SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management.
Structure, activation, and biology of calpain.
Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells.
The activity of calpains in lymphocytes is glucose-dependent and is decreased in diabetic patients.
The calpain family and human disease.
The calpain system and diabetes.
The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population.
The effect of calpain-10 gene polymorphism on the development of type 2 diabetes mellitus in a Turkish population.
The reduction of Calpain-10 expression is associated with risk polymorphisms in obese children.
The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CAPN10, APM1 and FUT6 genes.
Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: no evidence of association.
Type 2 diabetes candidate gene CAPN10: first, but not last.
Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.
Variants of calpain-10 gene and its association with type 2 diabetes mellitus in a Chinese population.
Variants within the calpain-10 gene and relationships with type 2 diabetes (T2DM) and T2DM-related traits among Tunisian Arabs.
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites.
Variation in the calpain-10 gene affects blood glucose levels in the British population.
Variation in the calpain-10 gene is associated with elevated triglyceride levels and reduced adipose tissue messenger ribonucleic acid expression in obese Swedish subjects.
Variation in the calpain-10 gene is not associated with gestational diabetes mellitus.
Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort.
Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome.
Variations in the calpain-10 gene are associated with the risk of type 2 diabetes and hypertension in northern Han Chinese population.
[Association analysis of SNP-63 and indel-19 variant in the calpain-10 gene with polycystic ovary syndrome in women of reproductive age].
[Association between calpain-10 gene polymorphism and risk of type 2 diabetes mellitus: a meta analysis]
[Calpain 10 as a susceptibility gene of type 2 diabetes]
[Calpain and pathology in view of structure-function relationships]
[Diabetes mellitus]
[Effect of the Gly972Arg, SNP43 and Prol2Ala polymorphisms of the genes IRS1, CAPN10 and PPARG2 on secondary failure to sulphonylurea and metformin in patients with type 2 diabetes in Yucatán, México]
[Perspectives on postgenome medicine: Gene therapy for diabetes mellitus]
[Single nucleotide polymorphisms in CAPN10 gene of Chinese population and its correlation with type 2 diabetes mellitus in Han people of northern China]
[Study of association of the SNP19 polymorphism of calpain 10 gene with type 2 diabetes in ethnic sub-groups of the Tunisian population: gene-environment interaction]
[Study on Calpain10 gene polymorphism in Chinese type 2 diabetes families]
[The impact of calpain-10 gene combined-SNP variation on type 2 diabetes mellitus and its related metabolic traits]
[The UCSNP44 variation of calpain 10 gene on NIDDM1 locus and its impact on plasma glucose levels in type 2 diabetic patients]
[Type 2 diabetes and genetic variations of calpain 10 gene]
Diabetes, Gestational
ADCY5, CAPN10 and JAZF1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes.
Association analysis of calpain 10 gene variants/haplotypes with gestational diabetes mellitus among Mexican women.
Calpain-10 haplotype combination and association with gestational diabetes mellitus.
Investigation of Calpain 10 (rs2975760) gene polymorphism in Asian Indians with Gestational Diabetes Mellitus.
Meta-analysis of the association between four CAPN10 gene variants and gestational diabetes mellitus.
TCF7L2, CAPN10 polymorphisms are associated with gestational diabetes mellitus (GDM) risks: a meta-analysis.
The Association Between the rs2975760 and rs3792267 Single Nucleotide Polymorphisms of Calpain 10 (CAPN10) and Gestational Diabetes Mellitus.
Variation in the calpain-10 gene is not associated with gestational diabetes mellitus.
[Single-nucleotide polymorphisms and genotype combinations in calpain-10 gene of gestational diabetes mellitus]
Diabetic Nephropathies
Calpain-10 drives podocyte apoptosis and renal injury in diabetic nephropathy.
Loss of calpain 10 causes mitochondrial dysfunction during chronic hyperglycemia.
Diabetic Retinopathy
Calpain 10 SNP-44 gene polymorphism affects susceptibility to type 2 diabetes mellitus and diabetic-related conditions.
Dyslipidemias
A genetic variant of the CAPN10 gene in Mexican subjects with dyslipidemia is associated with increased HDL-cholesterol concentrations after the consumption of a soy protein and soluble fiber dietary portfolio.
Esophageal Squamous Cell Carcinoma
Oncogene GAEC1 regulates CAPN10 expression which predicts survival in esophageal squamous cell carcinoma.
Glucose Intolerance
Assessing optimal neural network architecture for identifying disease-associated multi-marker genotypes using a permutation test, and application to calpain 10 polymorphisms associated with diabetes.
Association of CAPN10 gene with insulin sensitivity, glucose tolerance and renal function in essential hypertensive patients.
Association of the SNP-19 genotype 22 in the calpain-10 gene with elevated body mass index and hemoglobin A1c levels in Japanese.
Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians.
Glucose Metabolism Disorders
[Association of the calpain-10 gene polymorphism with glucose metabolism disorder in pregnant women]
Hirsutism
Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians.
CAPN10 UCSNP-43, UCSNP-19 and UCSNP-63 polymorphisms and metabolic syndrome in polycystic ovary syndrome.
Common single nucleotide polymorphisms in intron 3 of the calpain-10 gene influence hirsutism.
Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients.
Hyperandrogenism
Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients.
Hypercholesterolemia
Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels.
Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients.
Hyperglycemia
Loss of calpain 10 causes mitochondrial dysfunction during chronic hyperglycemia.
Hyperinsulinism
Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes.
[Association analysis of SNP-63 and indel-19 variant in the calpain-10 gene with polycystic ovary syndrome in women of reproductive age].
Hypertension
Calpain-10 Activity Underlies Angiotensin II-Induced Aldosterone Production in an Adrenal Glomerulosa Cell Model.
Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels.
Replication of calpain-10 genetic association with carotid intima-media thickness.
Variations in the calpain-10 gene are associated with the risk of type 2 diabetes and hypertension in northern Han Chinese population.
[Relationship between calpain-10 gene polymorphism, hypertension and plasma glucose]
Infertility
Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients.
Insulin Resistance
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.
A genetic variant of the CAPN10 gene in Mexican subjects with dyslipidemia is associated with increased HDL-cholesterol concentrations after the consumption of a soy protein and soluble fiber dietary portfolio.
Association analysis of calpain 10 gene variants/haplotypes with gestational diabetes mellitus among Mexican women.
Association of calpain-10 gene with microvascular function.
Association of CAPN10 gene with insulin sensitivity, glucose tolerance and renal function in essential hypertensive patients.
Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study.
Calpain inhibition and insulin action in cultured human muscle cells.
Calpain-10 and Adiponectin Gene Polymorphisms in Korean Type 2 Diabetes Patients.
Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes.
Calpain-10 gene polymorphism is associated with reduced beta(3)-adrenoceptor function in human fat cells.
Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome.
Calpain-10: from genome search to function.
Characterization of GLUT4 and calpain expression in healthy human skeletal muscle during fasting and refeeding.
Common single nucleotide polymorphisms in intron 3 of the calpain-10 gene influence hirsutism.
Coordinated control of both insulin secretion and insulin action through calpain-10-mediated regulation of exocytosis?
Genetic and environmental aspect of polycystic ovary syndrome.
Genetics of type 2 diabetes and insulin resistance: knowledge from human studies.
Insulin sensitivity of glucose disposal and lipolysis: no influence of common genetic variants in IRS-1 and CAPN10.
Metabolic syndrome: evidences for a personalized nutrition.
Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes.
Reduced skeletal muscle calpain-10 transcript level is due to a cumulative decrease in major isoforms.
Relationship between calpain-10 gene polymorphism and insulin resistance phenotypes in Chinese.
Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians.
Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells.
The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population.
Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Variation in the calpain-10 gene affects blood glucose levels in the British population.
Variations in the calpain-10 gene are associated with the risk of type 2 diabetes and hypertension in northern Han Chinese population.
[Association analysis of SNP-63 and indel-19 variant in the calpain-10 gene with polycystic ovary syndrome in women of reproductive age].
Intellectual Disability
New evidence for the role of calpain 10 in autosomal recessive intellectual disability: identification of two novel nonsense variants by exome sequencing in Iranian families.
Ischemic Stroke
Calpain 10 gene polymorphisms and the risk of ischaemic stroke in a Polish population.
Correlation between Calpain-10 single-nucleotide polymorphisms and obstructive sleep apnea/hypopnoea syndrome with ischemic stroke in a Chinese population: A population-based study.
Laryngeal Neoplasms
Calpain 10 gene and laryngeal cancer: A survival analysis.
CAPN10 alleles modify laryngeal cancer risk in the Spanish population.
Lung Neoplasms
Association of Diabetes Susceptibility Gene Calpain-10 with Pancreatic Cancer Among Smokers.
Melanoma
Exploiting Honokiol-induced ER stress CHOP activation inhibits the growth and metastasis of melanoma by suppressing the MITF and ?-catenin pathways.
Metabolic Syndrome
A genetic variant of the CAPN10 gene in Mexican subjects with dyslipidemia is associated with increased HDL-cholesterol concentrations after the consumption of a soy protein and soluble fiber dietary portfolio.
Calpain-10 interacts with plasma saturated fatty acid concentrations to influence insulin resistance in individuals with the metabolic syndrome.
CAPN10 UCSNP-43, UCSNP-19 and UCSNP-63 polymorphisms and metabolic syndrome in polycystic ovary syndrome.
Haplotype combination of Calpain-10 gene polymorphism is associated with metabolic syndrome in type 2 diabetes.
Metabolic syndrome: evidences for a personalized nutrition.
The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population.
Variation in the calpain-10 gene is associated with elevated triglyceride levels and reduced adipose tissue messenger ribonucleic acid expression in obese Swedish subjects.
Muscular Dystrophies
Calpain-related diseases.
Muscular Dystrophies, Limb-Girdle
Calpain-related diseases.
Myocardial Infarction
Analysis of the structure of calpain-10 and its interaction with the protease inhibitor SNJ-1715.
Neoplasm Metastasis
Differential gene expression analysis for osteosarcoma lung metastases.
Neoplasms
Analysis of the structure of calpain-10 and its interaction with the protease inhibitor SNJ-1715.
Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients.
The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination.
The positive is inside the negative: HER2-negative tumors can express the HER2 intracellular domain and present a HER2-positive phenotype.
Obesity
Association of the SNP-19 genotype 22 in the calpain-10 gene with elevated body mass index and hemoglobin A1c levels in Japanese.
Calpain-10 gene polymorphism is associated with reduced beta(3)-adrenoceptor function in human fat cells.
Calpain-10 is a component of the obesity-related quantitative trait locus Adip1.
Calpain-10 is a component of the obesity-related quantitative trait locus, Adip1.
Genetic association studies of obesity in Africa: a systematic review.
No evidence for involvement of the calpain-10 gene 'high-risk' haplotype combination for non-insulin-dependent diabetes mellitus in early onset obesity.
Obesity and developmental delay in a patient with uniparental disomy of chromosome 2.
Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites.
Variation in the calpain-10 gene is associated with elevated triglyceride levels and reduced adipose tissue messenger ribonucleic acid expression in obese Swedish subjects.
Obesity, Abdominal
Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes.
Pancreatic Neoplasms
Association of Diabetes Susceptibility Gene Calpain-10 with Pancreatic Cancer Among Smokers.
Polycystic Ovary Syndrome
111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women.
Association between CAPN10 UCSNP-43 gene polymorphism and polycystic ovary syndrome in Chilean women.
Association of CAPN10 SNPs and Haplotypes with Polycystic Ovary Syndrome among South Indian Women.
Calpain 10 gene single-nucleotide 44 polymorphism may have an influence on clinical and metabolic features in patients with polycystic ovary syndrome.
Calpain-10 genetic polymorphisms and polycystic ovary syndrome risk: A meta-analysis and meta-regression.
Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians.
Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels.
CAPN10 UCSNP-43, UCSNP-19 and UCSNP-63 polymorphisms and metabolic syndrome in polycystic ovary syndrome.
Comment: CAPN10 alleles are associated with polycystic ovary syndrome.
Comments on the latest meta-analysis of CAPN10 polymorphism associations with polycystic ovary syndrome.
Common polymorphisms of calpain-10 and the risk of polycystic ovary syndrome in Tunisian population: a case-control study.
Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome.
Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
Single-nucleotide polymorphism of INS, INSR, IRS1, IRS2, PPAR-G and CAPN10 genes in the pathogenesis of polycystic ovary syndrome.
Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients.
The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population.
Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome.
[Association analysis of SNP-63 and indel-19 variant in the calpain-10 gene with polycystic ovary syndrome in women of reproductive age].
[Relationship between single nucleotide polymorphism-56 of calpain-10 gene and glucose and lipid metabolism in polycystic ovary syndrome patients]
Pre-Eclampsia
Polymorphisms of interleukin-6, hepatic lipase and calpain-10 genes, and preeclampsia.
Retinal Degeneration
Involvement of calpain isoforms in retinal degeneration in WBN/Kob rats.
Sleep Apnea, Obstructive
Correlation between Calpain-10 single-nucleotide polymorphisms and obstructive sleep apnea/hypopnoea syndrome with ischemic stroke in a Chinese population: A population-based study.
Stomach Neoplasms
The calpain family and human disease.
The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination.
Stroke
Analysis of the structure of calpain-10 and its interaction with the protease inhibitor SNJ-1715.
Calpain 10 gene polymorphisms and the risk of ischaemic stroke in a Polish population.