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Information on EC 3.4.22.B27 - calpain 7 and Organism(s) Mus musculus and UniProt Accession Q9R1S8

for references in articles please use BRENDA:EC3.4.22.B27
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B27 calpain 7
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This record set is specific for:
Mus musculus
UNIPROT: Q9R1S8
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Word Map
  • 3.4.22.B27
  • calpains
  • endosomal
  • escrt
  • escrt-iii
  • penta-ef-hand
  • hek293t
  • autolytic
  • ist1
  • mit-interacting
  • flag-tagged
  • microtubule-interacting
  • pulldown
  • multivesicular
  • strep-tagged
  • epitope-tagged
  • chmp1b
  • calpain-like
  • calcium-activated
  • dominant-negative
The taxonomic range for the selected organisms is: Mus musculus
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
broad endopeptidase specificity
Synonyms
calpain-7, capn7, calpain 7, palbh, capn 7, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
capn 7
-
-
-
-
PalB homolog
-
-
-
-
PalBH
-
-
-
-
CAS REGISTRY NUMBER
COMMENTARY hide
78990-62-2
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
peptide + H2O
hydrolyzed peptide
show the reaction diagram
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CAN7_MOUSE
813
0
92564
Swiss-Prot
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in COS cells
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Homo sapiens (Q7Z479), Homo sapiens (Q9Y6W3), Mus musculus (Q9R1S8)
Manually annotated by BRENDA team
Futai, E.; Kubo, T.; Sorimachi, H.; Suzuki, K.; Maeda, T.
Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PALB.
Biochim. Biophys. Acta
1517
316-319
2001
Homo sapiens (Q9Y6W3), Homo sapiens, Mus musculus (Q9R1S8), Mus musculus
Manually annotated by BRENDA team
Franz, T.; Vingron, M.; Boehm, T.; Dear.T.N.
Capn7: a highly divergent vertebrate calpain with a novel C-terminal domain
Mamm. Genome
10
318-321
1999
Mus musculus (Q9R1S8)
Manually annotated by BRENDA team