Disease on EC 3.4.22.6 - chymopapain
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Abscess
Fulminating septicemia secondary to oxygen-ozone therapy for lumbar disc herniation: case report.
Anaphylaxis
Anaphylactic reactions following intradiscal injection of chymopapain under local anesthesia.
Anaphylaxis
Anaphylactic reactions following the intradiscal injection of chymopapain under local anesthesia.
Anaphylaxis
Anaphylactic shock associated with chymopapain skin test. A case report and review of the literature.
Anaphylaxis
Chymopapain allergy: case reports and identification of patients at risk for chymopapain anaphylaxis.
Anaphylaxis
Correlation between hypersensitivity to parenteral chymopapain and the presence of IgE anti-chymopapain antibody.
Anaphylaxis
Five-year results from chemonucleolysis with chymopapain or collagenase: a prospective randomized study.
Anaphylaxis
Prevention of chymopapain anaphylaxis by screening chemonucleolysis candidates with cutaneous chymopapain testing.
Anaphylaxis
Prevention of chymopapain anaphylaxis by screening chemonucleolysis candidates with cutaneous chymopapain testing. A preliminary report.
Anaphylaxis
Prospective evaluation of chymopapain sensitivity in patients undergoing chemonucleolysis.
Anaphylaxis
Safety of chemonucleolysis. Adverse effects reported in the United States, 1982-1991.
Anaphylaxis
The use of antihistamines in the prevention and treatment of anaphylaxis and anaphylactoid reactions.
Anaphylaxis
Use of prophylactic combined H1 and H2 antagonists reduces mortality in chymopapain anaphylaxis.
Anaphylaxis
[Chemonucleolysis using chymopapain and collagenase. 3-year results of a prospective randomized study]
Anaphylaxis
[Chymopapain allergy. Diagnostic value of a skin test before and after chemonucleolysis]
Anaphylaxis
[Clinical experience with intradisk chymopapain administration in lumbar intervertebral disk displacement]
Anaphylaxis
[Immunologic methods of study for evaluating the risk of anaphylactic reactions in intradisk chymopapain injections]
Anaphylaxis
[Intradiscal injection of hypertonic saline, phenol-glycerin and osmic acid for the treatment of lumbar disc herniation: an experimental study]
Bone Resorption
The effect of bone remodeling inhibition by zoledronic acid in an animal model of cartilage matrix damage.
Carcinoma, Hepatocellular
[Cytotoxicity of chymopapain combined with pingyangmycin on mouse hepatoma cell line hepa-6]
Cerebral Hemorrhage
Multiple cerebral hemorrhages following chymopapain chemonucleolysis. Case report.
Colonic Neoplasms
Intracellularly biorecognizable derivatives of 5-fluorouracil. Implications for site-specific delivery in the human condition.
Discitis
Fulminating septicemia secondary to oxygen-ozone therapy for lumbar disc herniation: case report.
Drug Hypersensitivity
[Sensitization to chymopapain in patients treated with chemonucleolysis]
Erythema
[Changes in plasma histamine and catecholamines levels after injection of chymopapain in chemonucleolysis]
Hyperalgesia
Chymopapain-induced reduction of proinflammatory phospholipase A2 activity and amelioration of neuropathic behavioral changes in an in vivo model of acute sciatica.
Hypersensitivity
Brain Activation in a Cynomolgus Macaque Model of Chymopapain-Induced Discogenic Low Back Pain: A Preliminary Study.
Hypersensitivity
Chymopapain allergy: case reports and identification of patients at risk for chymopapain anaphylaxis.
Hypersensitivity
Correlation between hypersensitivity to parenteral chymopapain and the presence of IgE anti-chymopapain antibody.
Hypersensitivity
Immunoglobulin E antibodies to papaya proteinases and their relevance to chemonucleolysis.
Hypersensitivity
Incidence and risk factors for latent sensitization to chymopapain: predictive skin-prick tests in 700 candidates for chemonucleolysis.
Hypersensitivity
Local ocular anaphylaxis to papain enzyme contained in a contact lens cleansing solution.
Hypersensitivity
Prospective comparative study of intradiscal high-dose and low-dose collagenase versus chymopapain.
Hypersensitivity
[Allergy to chymopapain: value of predictive tests before chemonucleolysis]
Hypersensitivity
[Chymopapain allergy. Diagnostic value of a skin test before and after chemonucleolysis]
Hypersensitivity
[Clinical experience with intradisk chymopapain administration in lumbar intervertebral disk displacement]
Hypersensitivity
[Detection of patients at risk of allergy to chymopapain before and after chemonucleolysis. Choice of preventive medication]
Hypersensitivity
[Incidence and prevention of allergic reactions following chemonucleolysis with chymopapain]
Infections
Safety of chemonucleolysis. Adverse effects reported in the United States, 1982-1991.
Intervertebral Disc Degeneration
Modic changes, possible causes and relation to low back pain.
Intervertebral Disc Degeneration
The changes in the intervertebral disc after chemonucleolysis demonstrated by magnetic resonance imaging.
Intervertebral Disc Degeneration
The long-term effect of chemonucleolysis on the intervertebral disc as assessed by magnetic resonance imaging.
Intervertebral Disc Degeneration
The use of chymopapain in degenerative disc disease: a preliminary report.
Intervertebral Disc Displacement
A randomized, double-blind study to compare low-dose with standard-dose chymopapain in the treatment of herniated lumbar intervertebral discs.
Intervertebral Disc Displacement
Adolescent disc protrusions. A long term follow-up of chymopapain therapy.
Intervertebral Disc Displacement
Adolescent disc protrusions. A long-term follow-up of surgery compared to chymopapain.
Intervertebral Disc Displacement
Cervical nucleolysis: indications, technique, results. 190 patients.
Intervertebral Disc Displacement
Chemonucleolysis. The relationship of the physical findings, discography, and myelography to the clinical result.
Intervertebral Disc Displacement
Chymopapain chemonucleolysis: correlation of diagnostic radiographic factors and clinical outcome.
Intervertebral Disc Displacement
Chymopapain for the treatment of intervertebral disc herniation. A preliminary report of a double-blind study.
Intervertebral Disc Displacement
Chymopapain for the treatment of intervertebral disc herniation. The final report of a double-blind study.
Intervertebral Disc Displacement
Chymopapain versus conventional surgery for lumbar disc herniation. 10-year results of treatment.
Intervertebral Disc Displacement
Combined biochemical and clinical investigation of chemonucleolysis failures.
Intervertebral Disc Displacement
Comparison of tissue reaction with chondroitinase ABC and chymopapain in rabbits as the basis of clinical application in chemonucleolysis.
Intervertebral Disc Displacement
Computed tomography and differential diagnosis of the extruded lumbar disc.
Intervertebral Disc Displacement
Computed tomography scanning after chymopapain injection for herniated nucleus pulposus. A prospective study.
Intervertebral Disc Displacement
Duration of symptoms and disc configuration in chemonucleolysis.
Intervertebral Disc Displacement
Experimental chemonucleolysis with chymopapain in canine intervertebral disks.
Intervertebral Disc Displacement
Experimental studies on the effects of recombinant human matrix metalloproteinases on herniated disc tissues--how to facilitate the natural resorption process of herniated discs.
Intervertebral Disc Displacement
Injection of cymopapain into intervertebral discs. Preliminary report on 72 patients with symptoms of disc disease.
Intervertebral Disc Displacement
Intradiscal pressure after intradiscal injection of hypertonic saline: an experimental study.
Intervertebral Disc Displacement
Intradiscal pressure after repeat intradiscal injection of hypertonic saline: an experimental study.
Intervertebral Disc Displacement
Intraoperative chymopapain in lumbar laminotomy for disc disease: a less invasive technique.
Intervertebral Disc Displacement
Laser-assisted diskectomy performed by an internist resulting in cauda equina syndrome.
Intervertebral Disc Displacement
Long-term changes in the magnetic resonance image after chemonucleolysis.
Intervertebral Disc Displacement
Low-dose, low-volume chemonucleolysis. A biochemical study.
Intervertebral Disc Displacement
Lumbar disc herniations: the predictive value of the Health Attribution Test (HAT) and the Minnesota Multiphasic Personality Inventory (MMPI).
Intervertebral Disc Displacement
Lumbar discal herniation in the elderly: long-term results of chymopapain chemonucleolysis.
Intervertebral Disc Displacement
Magnetic resonance imaging findings 10 years after treatment for lumbar disc herniation.
Intervertebral Disc Displacement
Modic changes, possible causes and relation to low back pain.
Intervertebral Disc Displacement
Percutaneous lumbar diskectomy using a new aspiration probe: porcine and cadaver model.
Intervertebral Disc Displacement
Plasma radio-frequency-based diskectomy for treatment of cervical herniated nucleus pulposus: feasibility, safety, and preliminary clinical results.
Intervertebral Disc Displacement
Post-chymopapain (chemonucleolysis)--clinical and computed tomography correlation: preliminary results.
Intervertebral Disc Displacement
Sciatica caused by disc herniation: Why is Chymopapain Chemonucleolysis denied to our patients?
Intervertebral Disc Displacement
Serial changes observed by magnetic resonance imaging in the intervertebral disc after chemonucleolysis. A consideration of the mechanism of chemonucleolysis.
Intervertebral Disc Displacement
The dose-related effect of intradiscal chymopapain on rabbit intervertebral discs.
Intervertebral Disc Displacement
The effect of spondylosis on the outcome of chemonucleolysis.
Intervertebral Disc Displacement
The long-term results of chymopapain. Ten-year follow-up of 268 patients after chemonucleolysis.
Intervertebral Disc Displacement
The treatment of herniated disc in Australia. Costs and benefits of intradiscal injection of chymopapain and surgery.
Intervertebral Disc Displacement
Transforaminal posterolateral endoscopic discectomy with or without the combination of a low-dose chymopapain: a prospective randomized study in 280 consecutive cases.
Intervertebral Disc Displacement
Treatment of chronic low back pain - new approaches on the horizon.
Intervertebral Disc Displacement
Treatment of lumbar disc herniation by chymopapain chemonucleolysis. A report on 120 patients.
Intervertebral Disc Displacement
[Chemonucleolysis of lumbar disk prolapse. Choice and complications]
Intervertebral Disc Displacement
[Clinical experience with intradisk chymopapain administration in lumbar intervertebral disk displacement]
Intervertebral Disc Displacement
[Failure of chemonucleolysis and its surgical treatment. Apropos of 268 cases]
Intervertebral Disc Displacement
[Herniation of a lumbar disk in the elderly. Results of chemonucleolysis]
Intervertebral Disc Displacement
[Lumbar disk prolapses and radiological spinal intervention. What do the randomized controlled trials say?]
Intervertebral Disc Displacement
[Nucleolytic action of chondroitinase ABC on the lumbar disc of the rabbit]
Intervertebral Disc Displacement
[Treatment by nucleolysis using chymopapain of disk hernias of purely lumbalgic form]
Intervertebral Disc Displacement
[Treatment of soft cervical hernia by percutaneous intradiscal injection of aprotinin]
Intervertebral Disc Displacement
[Unsatisfactory results of intradiscal injection of triamcinolone hexacetonide in the treatment of sciatica caused by intervertebral disk herniation]
Myelitis, Transverse
Possible role of collagen in transverse myelitis and chymopapain-induced paraplegia.
Oculomotor Nerve Diseases
Acute encephalopathy and third-nerve palsy after chymopapain injection.
Pruritus
[Changes in plasma histamine and catecholamines levels after injection of chymopapain in chemonucleolysis]
Radiculopathy
Experimental studies on the effect of chymopapain on nerve root compression caused by intervertebral disk material.
Sciatic Neuropathy
Chymopapain-induced reduction of proinflammatory phospholipase A2 activity and amelioration of neuropathic behavioral changes in an in vivo model of acute sciatica.
Sciatica
Adolescent disc protrusions. A long-term follow-up of surgery compared to chymopapain.
Sciatica
Backache and sciatica. A report of 90 patients treated by intradiscal injection of chymopapain (discase).
Sciatica
Biomechanical analysis of canine intervertebral discs after chymopapain injection. A preliminary report.
Sciatica
Chemonucleolysis. The relationship of the physical findings, discography, and myelography to the clinical result.
Sciatica
Chymopapain for the treatment of intervertebral disc herniation. A preliminary report of a double-blind study.
Sciatica
Chymopapain for the treatment of intervertebral disc herniation. The final report of a double-blind study.
Sciatica
Chymopapain-induced reduction of proinflammatory phospholipase A2 activity and amelioration of neuropathic behavioral changes in an in vivo model of acute sciatica.
Sciatica
Immunoglobulin E antibodies to papaya proteinases and their relevance to chemonucleolysis.
Sciatica
Mechanism of action of intradiscal chymopapain in the treatment of sciatica: a clinical, biochemical, and radiological study.
Sciatica
Safer proteinase treatment of sciatica. A biochemical preview of chymopapain inhibitors.
Sciatica
Safety and efficacy of chymopapain (Chymodiactin) in herniated nucleus pulposus with sciatica. Results of a randomized, double-blind study.
Sciatica
Safety and efficacy of chymopapain (Discase) in the treatment of sciatica due to a herniated nucleus pulposus. Results of a randomized, double-blind study.
Sciatica
Sciatica caused by disc herniation: Why is Chymopapain Chemonucleolysis denied to our patients?
Sciatica
Treatment of sciatica. A comparative survey of complications of surgical treatment and nucleolysis with chymopapain.
Sciatica
[Treatment of low back pain and sciatica by intradiskal injection of chymopapain. Comparative analysis of the results of diskectomy and chemonucleolysis]
Sciatica
[Treatment of lumbar sciatica with chymopapain injections in the intervertebral disk. A 7-year clinical study]
Sciatica
[Unsatisfactory results of intradiscal injection of triamcinolone hexacetonide in the treatment of sciatica caused by intervertebral disk herniation]
Scoliosis
Spinal flexibility increase after chymopapain injection is dose dependent: a possible alternative to anterior release in scoliosis.
Spasm
A randomized, double-blind study to compare low-dose with standard-dose chymopapain in the treatment of herniated lumbar intervertebral discs.
Spinal Cord Injuries
Intrathecal injection of a specific enzyme in rats as a model for chemically induced spinal cord injury.
Subarachnoid Hemorrhage
Hemorrhagic complications after the lumbar injection of chymopapain.
Subarachnoid Hemorrhage
Subarachnoid hemorrhage following chymopapain chemonucleolysis. Case report.
Synovitis
Scintigraphic evaluation of dogs with acute synovitis after treatment with glucosamine hydrochloride and chondroitin sulfate.
Tachycardia
[Changes in plasma histamine and catecholamines levels after injection of chymopapain in chemonucleolysis]
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