Reference on EC 3.4.22.57 - caspase-4
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Garcia-Calvo, M.; Peterson, E.P.; Leiting, B.; Ruel, R.; Nicholson, D.W.; Thornberry, N.A.
Inhibition of human caspases by peptide-based and macromolecular inhibitors
J. Biol. Chem.
273
32608-32613
1998
Homo sapiens
Garcia-Calvo, M.; Peterson, E.P.; Rasper, D.M.; Vaillancourt, J.P.; Zamboni, R.; Nicholson, D.W.; Thornberry, N.A.
Purification and catalytic properties of human caspase family members
Cell Death Differ.
6
362-369
1999
Homo sapiens
Chang, H.Y.; Yang, X.
Proteases from cell suicide: functions and regulation of caspases
Microbiol. Mol. Biol. Rev.
64
821-846
2000
Homo sapiens
Thornberry, N.A.; Rano, T.A.; Peterson, E.P.; et al.
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
J. Biol. Chem.
272
17907-17911
1997
Homo sapiens
van de Craen, M.; Vandenabeele, P.; Declercq, W.; van den Brande, I.; van Loo, G.; Molemans, F.; Schotte, P.; van Criekinge, W.; Beyaert, R.; Fiers, W.
Characterization of seven murine caspase family members
FEBS Lett.
403
61-69
1997
Mus musculus (P70343), Mus musculus
Talanian, R.V.; Quinlan, C.; Trautz, S.; Hackett, M.C.; Mankovich, J.A.; Banach, D.; Ghayur, T.; Brady, K.D.; Wong, W.W.
Substrate specificities of caspase family proteases
J. Biol. Chem.
272
9677-9682
1997
Homo sapiens
Margolin, N.; Raybuck, S.A.; Wilson, K.P.; Chen, W.; Fox, T.; Gu, Y.; Livingston, D.J.
Substrate and inhibitor specificity of interleukin-1beta-converting enzyme and related caspases
J. Biol. Chem.
272
7223-7228
1997
Homo sapiens
Wang, S.; Miura, M.; Jung, Y.K.; Zhu, H.; Gagliardini, V.; Shi, L.; Greenberg, A.H.; Yuan, J.
Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE
J. Biol. Chem.
271
20580-20587
1996
Mus musculus (P70343), Mus musculus C57BL/6 X CBA (P70343)
Munday N.A.; Vaillancourt J.P.; Ali A.; Casano F.J.; Miller D.K.; Molineaux S.M.; Yamin T.T.; Yu V.L.; Nicholson D.W.
Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases
J. Biol. Chem.
270
15870-15876
1995
Homo sapiens (P49662)
Kamada, S.; Funahashi, Y.; Tsujimoto, Y.
Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases
Cell Death Differ.
4
473-478
1997
Homo sapiens
Fassy, F.; Krebs, O.; Rey, H.; Komara, B.; Gillard, C.; Capdevila, C.; Yea, C.; Faucheu, C.; Blanchet, A.M.; Miossec, C.; Diu-Hercend, A.
Enzymic activity of two caspases related to interleukin-1beta-converting enzyme
Eur. J. Biochem.
253
76-83
1998
Homo sapiens
Faucheu, C.; Diu, A.; Chan, A.W.E.; Blanchet, A.M.; Miossec, C.; Herve, F.; Collard-Dutilleul, V.; Gu, Y.; Aldape, R.A.; Lippke, J.A.; Rocher, C.; Su, M.S.S.; Livingston, D.J.; Hercend, T.; Lalanne, J.L.
A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells
EMBO J.
14
1914-1922
1995
Homo sapiens (P49662)
Kamens, J.; Paskind, M.; Hugunin, M.; Talanian, R.V.; Allen, H.; Banach, D.; Bump, N.J.; Hackett, M.C.; Johnston, C.G.; Li, P.; Mankovich, J.A.; Terranova, M.; Ghayur, T.
Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases
J. Biol. Chem.
270
15250-15256
1995
Homo sapiens (P49662)
Wang, X.; Narayanan, M.; Bruey, J.M.; Rigamonti, D.; Cattaneo, E.; Reed, J.C.; Friedlander, R.M.
Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death
Biochim. Biophys. Acta
1762
742-754
2006
Homo sapiens
Hitomi, J.; Katayama, T.; Eguchi, Y.; Kudo, T.; Taniguchi, M.; Koyama, Y.; Manabe, T.; Yamagishi, S.; Bando, Y.; Imaizumi, K.; Tsujimoto, Y.; Tohyama, M.
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
J. Cell Biol.
165
347-356
2004
Homo sapiens
Mulugeta, S.; Maguire, J.A.; Newitt, J.L.; Russo, S.J.; Kotorashvili, A.; Beers, M.F.
Misfolded BRICHOS SP-C mutant proteins induce apoptosis via caspase-4- and cytochrome c-related mechanisms
Am. J. Physiol. Lung Cell Mol. Physiol.
293
L720-L729
2007
Homo sapiens
Lakshmanan, U.; Porter, A.G.
Caspase-4 interacts with TNF receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kappaB-dependent production of IL-8 and CC chemokine ligand 4 (macrophage-inflammatory protein-1)
J. Immunol.
179
8480-8490
2007
Homo sapiens (P49662), Homo sapiens
Yukioka, F.; Matsuzaki, S.; Kawamoto, K.; Koyama, Y.; Hitomi, J.; Katayama, T.; Tohyama, M.
Presenilin-1 mutation activates the signaling pathway of caspase-4 in endoplasmic reticulum stress-induced apoptosis
Neurochem. Int.
52
683-687
2008
Homo sapiens
Yi, J.Y.; Hirabayashi, Y.; Choi, Y.K.; Kodama, Y.; Kanno, J.; Han, J.H.; Inoue, T.; Yoon, B.I.
Benzene activates caspase-4 and -12 at the transcription level, without an association with apoptosis, in mouse bone marrow cells lacking the p53 gene
Arch. Toxicol.
83
795-803
2009
Mus musculus
Koehn, S.; Trueck, M.; Poehlmann, T.G.; Schleussner, E.; Markert, U.R.; Seyfarth, L.
Assessment of caspase-4 released free AFC by RP-HPLC and fluorescence detection
J. Chromatogr. B
874
111-114
2008
Homo sapiens
Kajiwara, Y.; Akram, A.; Katsel, P.; Haroutunian, V.; Schmeidler, J.; Beecham, G.; Haines, J.L.; Pericak-Vance, M.A.; Buxbaum, J.D.
FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4
PLoS ONE
4
e5071
2009
Homo sapiens, no activity in Mus musculus
Sollberger, G.; Strittmatter, G.E.; Kistowska, M.; French, L.E.; Beer, H.D.
Caspase-4 is required for activation of inflammasomes
J. Immunol.
188
1992-2000
2012
Homo sapiens
Yamamuro, A.; Kishino, T.; Ohshima, Y.; Yoshioka, Y.; Kimura, T.; Kasai, A.; Maeda, S.
Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells
J. Pharmacol. Sci.
115
239-243
2011
Homo sapiens
Valentin-Acevedo, A.; Sinquett, F.L.; Covey, L.R.
c-Rel deficiency increases caspase-4 expression and leads to ER stress and necrosis in EBV-transformed cells
PLoS ONE
6
e25467
2011
Homo sapiens
Kobayashi, T.; Ogawa, M.; Sanada, T.; Mimuro, H.; Kim, M.; Ashida, H.; Akakura, R.; Yoshida, M.; Kawalec, M.; Reichhart, J.M.; Mizushima, T.; Sasakawa, C.
The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection
Cell Host Microbe
13
570-583
2013
Cavia porcellus, Homo sapiens
Grimstad, O.; Husebye, H.; Espevik, T.
TLR3 mediates release of IL-1beta and cell death in keratinocytes in a caspase-4 dependent manner
J. Dermatol. Sci.
72
45-53
2013
Homo sapiens
Kajiwara, Y.; Schiff, T.; Voloudakis, G.; Gama Sosa, M.A.; Elder, G.; Bozdagi, O.; Buxbaum, J.D.
A critical role for human caspase-4 in endotoxin sensitivity
J. Immunol.
193
335-343
2014
Homo sapiens
Yang, H.J.; Wang, M.; Wang, L.; Cheng, B.F.; Lin, X.Y.; Feng, Z.W.
NF-kappaB regulates caspase-4 expression and sensitizes neuroblastoma cells to Fas-induced apoptosis
PLoS ONE
10
e0117953
2015
Homo sapiens
Schmid-Burgk, J.L.; Gaidt, M.M.; Schmidt, T.; Ebert, T.S.; Bartok, E.; Hornung, V.
Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells
Eur. J. Immunol.
45
2911-2917
2015
Homo sapiens (P49662), Homo sapiens
Vigano, E.; Diamond, C.E.; Spreafico, R.; Balachander, A.; Sobota, R.M.; Mortellaro, A.
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes
Nat. Commun.
6
8761
2015
Homo sapiens (P49662), Homo sapiens
Lagrange, B.; Benaoudia, S.; Wallet, P.; Magnotti, F.; Provost, A.; Michal, F.; Martin, A.; Di Lorenzo, F.; Py, B.F.; Molinaro, A.; Henry, T.
Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
Nat. Commun.
9
242
2018
Homo sapiens (P49662), Homo sapiens
Casson, C.N.; Yu, J.; Reyes, V.M.; Taschuk, F.O.; Yadav, A.; Copenhaver, A.M.; Nguyen, H.T.; Collman, R.G.; Shin, S.
Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens
Proc. Natl. Acad. Sci. USA
112
6688-6693
2015
Homo sapiens (P49662), Homo sapiens
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