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Disease on EC 3.4.22.40 - bleomycin hydrolase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Coronary Syndrome
Association of homocysteine thiolactonase activity and PON1 polymorphisms with the severity of acute coronary syndrome.
Adenocarcinoma
Purification of bleomycin hydrolase with a monoclonal antibody and its characterization.
Adenoma
Immunohistochemical detection of prolactin in clinically non-functioning pituitary adenomas.
Alzheimer Disease
Analysis of association between bleomycin hydrolase and apolipoprotein E polymorphism in Alzheimer's disease.
Association between bleomycin hydrolase and Alzheimer's disease in caucasians.
Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase.
Bleomycin hydrolase immunoreactivity in senile plaque in the brains of patients with Alzheimer's disease.
Bleomycin hydrolase is associated with risk of sporadic Alzheimer's disease.
Confirmation of the association between bleomycin hydrolase genotype and Alzheimer's disease.
Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan.
Human bleomycin hydrolase regulates the secretion of amyloid precursor protein.
Lack of association between bleomycin hydrolase gene polymorphism and Alzheimer's disease in Japanese people.
Reduced Homocysteine-Thiolactonase Activity in Alzheimer's Disease.
Reduced homocysteine-thiolactonase activity in Alzheimer's disease.
Regional and cellular distribution of bleomycin hydrolase mRNA in human brain: comparison between Alzheimer's diseased and control brains.
Atherosclerosis
Association of paraoxonase 55 and 192 gene polymorphisms on serum homocysteine concentrations in preeclampsia.
Decreased paraoxonase 1 (PON1) lactonase activity in hemodialyzed and renal transplanted patients. A novel cardiovascular biomarker in end-stage renal disease.
Genetic determinants of homocysteine thiolactonase activity in humans: implications for atherosclerosis.
Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus.
Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay.
bleomycin hydrolase deficiency
Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease.
Breast Neoplasms
Gene characterization, promoter analysis, and chromosomal localization of human bleomycin hydrolase.
Serum bioactive lactogenic hormone levels in women with familial breast cancer and their relatives.
Carcinoma
Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance.
Potentiation of the cytotoxicity of peplomycin against Ehrlich ascites carcinoma by bleomycin hydrolase inhibitors.
Purification of bleomycin hydrolase with a monoclonal antibody and its characterization.
Carcinoma, Hepatocellular
Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method.
Cardiovascular Diseases
Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus.
Chromosome Disorders
LRH-stimulated release of bioactive and immunoreactive LH in a patient with the XX male syndrome.
Coronary Artery Disease
Serum PON-1 Activity but not Q192R Polymorphism is Related to the Extent of Atherosclerosis.
Dementia
Polymorphisms of the human apolipoprotein E promoter and bleomycin hydrolase gene: risk factors for Alzheimer's dementia?
Dermatitis
A case of bleomycin-induced flagellate dermatitis: A case report.
Dermatitis, Atopic
Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.
Bleomycin Hydrolase Is Regulated Biphasically in a Differentiation- and Cytokine-dependent Manner: RELEVANCE TO ATOPIC DERMATITIS.
Seasonal variability of epidermal Bleomycin Hydrolase activity in healthy children and pediatric patients with atopic dermatitis.
Diabetes Mellitus
Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus.
Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay.
Relations of lysophosphatidylcholine in low-density lipoprotein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus.
Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay.
Relations of lysophosphatidylcholine in low-density lipoprotein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in patients with type 2 diabetes mellitus.
Diabetic Nephropathies
Evaluation of Paraoxonase, Arylesterase, and Homocysteine Thiolactonase Activities in Patients with Diabetes and Incipient Diabetes Nephropathy.
Relations of lysophosphatidylcholine in low-density lipoprotein with serum lipoprotein-associated phospholipase A2, paraoxonase and homocysteine thiolactonase activities in patients with type 2 diabetes mellitus.
Hodgkin Disease
Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance.
Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.
Hyperhomocysteinemia
Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis.
Hyperhomocysteinemia and Bleomycin Hydrolase Modulate the Expression of Mouse Brain Proteins Involved in Neurodegeneration.
Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease.
Hypersensitivity
BLH1 codes for a yeast thiol aminopeptidase, the equivalent of mammalian bleomycin hydrolase.
Hypertension
[Circadian blood pressure rhythm and its characterization in isolated systolic hypertension (ISH)]
Leukemia
Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1.
Leydig Cell Tumor
Circulatory half-life but not interaction with the lutropin/chorionic gonadotropin receptor is modulated by sulfation of bovine lutropin oligosaccharides.
Lymphoma
Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance.
Histopathological and immunohistochemical study of atypical lymphoid hyperplasia and benign lymphoid hyperplasia of the stomach.
Malnutrition
Androgen receptor function during undernutrition.
Metabolic Syndrome
Modulation of paraoxonase 1 and protein N-homocysteinylation by leptin and the synthetic liver X receptor agonist T0901317 in the rat.
Neoplasms
Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1.
Activated T-cell subsets in benign lymphoid hyperplasias and B-cell non-Hodgkin's lymphomas.
Biochemical and cellular determinants of bleomycin cytotoxicity.
Bleomycin hydrolase activity and cytotoxicity in human tumors.
Breast Cancer-Derived Microvesicles Are the Source of Functional Metabolic Enzymes as Potential Targets for Cancer Therapy.
Castleman's disease. Angiofollicular benign lymph-node hyperplasia. Radiological features in the differential diagnosis of vascular tumours of the pelvis.
Cellular resistance to bleomycin in Saccharomyces cerevisiae is not affected by changes in bleomycin hydrolase levels.
Circulatory half-life but not interaction with the lutropin/chorionic gonadotropin receptor is modulated by sulfation of bovine lutropin oligosaccharides.
Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance.
Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease.
Cys102 and His398 are required for bleomycin-inactivating activity but not for hexamer formation of yeast bleomycin hydrolase.
Downsizing the BAD BH3 peptide to small constrained ?-helices with improved ligand efficiency.
Genetic variation in the bleomycin hydrolase gene and bleomycin-induced pulmonary toxicity in germ cell cancer patients.
Genomic structure and genetic mapping of the human neutral cysteine protease bleomycin hydrolase.
Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method.
Immunohistochemical detection of prolactin in clinically non-functioning pituitary adenomas.
Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.
Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure.
Osteosarcoma of limb bones: a clinical, radiological and histopathological diagnostic agreement at Black Lion Teaching Hospital, Ethiopia.
Variation in bleomycin hydrolase gene is associated with reduced survival after chemotherapy for testicular germ cell cancer.
Yeast bleomycin hydrolase is a DNA-binding cysteine protease. Identification, purification, biochemical characterization.
Yeast cysteine proteinase gene ycp1 induces resistance to bleomycin in mammalian cells.
Neoplasms, Germ Cell and Embryonal
Genetic variation in the bleomycin hydrolase gene and bleomycin-induced pulmonary toxicity in germ cell cancer patients.
Variation in bleomycin hydrolase gene is associated with reduced survival after chemotherapy for testicular germ cell cancer.
Neurodegenerative Diseases
[Apolipoprotein E and bleomycin hydrolase. Polymorphisms: association with neurodegenerative diseases]
Neurofibromatoses
Gene characterization, promoter analysis, and chromosomal localization of human bleomycin hydrolase.
Neurofibromatosis 1
Gene characterization, promoter analysis, and chromosomal localization of human bleomycin hydrolase.
Osteopetrosis
Chicken strain G-B1 exhibits a relative resistance to avian osteopetrosis.
Pre-Eclampsia
Association of paraoxonase 55 and 192 gene polymorphisms on serum homocysteine concentrations in preeclampsia.
Pulmonary Fibrosis
Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice.
Genomic structure and genetic mapping of the human neutral cysteine protease bleomycin hydrolase.
Renal Insufficiency
Relationship between serum paraoxonase and homocysteine thiolactonase activity, adipokines, and asymmetric dimethyl arginine concentrations in renal transplant patients.
Retinoblastoma
Subconjunctival carboplatin therapy and cryotherapy in the treatment of transgenic murine retinoblastoma.
Sarcoma 180
Purification of bleomycin hydrolase with a monoclonal antibody and its characterization.
Spinal Stenosis
Comparison of unilateral hemilaminotomy and bilateral hemilaminotomy according to dural sac area in lumbar spinal stenosis.
Stroke
Echogenicity variations from porcine blood I: the "bright collapsing ring" under pulsatile flow.
Tachycardia
Autonomic reflexes in borderline hypertensives.
Thrombocytopenia
Comparison of the platelet pro-aggregatory effect of conventional unfractionated heparins and a low molecular weight heparin fraction (CY 222).
Thrombosis
Relationship between thiolactonase activity and hyperhomocysteinemia according to MTHFR gene polymorphism in Tunisian Behçet's disease patients.
Turner Syndrome
LRH-stimulated release of bioactive and immunoreactive LH in a patient with the XX male syndrome.
Uterine Cervical Neoplasms
Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1.