Disease on EC 3.4.22.10 - streptopain
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Anti-Glomerular Basement Membrane Disease
The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease.
Arthritis, Infectious
Expression and characterization of group A Streptococcus extracellular cysteine protease recombinant mutant proteins and documentation of seroconversion during human invasive disease episodes.
Bacteremia
Expression and characterization of group A Streptococcus extracellular cysteine protease recombinant mutant proteins and documentation of seroconversion during human invasive disease episodes.
Bacteremia
Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production in the mouse model of group A streptococcal infection.
Cellulitis
Expression and characterization of group A Streptococcus extracellular cysteine protease recombinant mutant proteins and documentation of seroconversion during human invasive disease episodes.
Fasciitis, Necrotizing
Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease.
Fasciitis, Necrotizing
Diagnosis of group A streptococcal necrotizing fasciitis by using PCR to amplify the streptococcal pyrogenic exotoxin B gene.
Foodborne Diseases
Time course of virulence factors produced by group A streptococcus during a food-borne epidemic.
Glomerulonephritis
Acute poststreptococcal glomerulonephritis with acute interstitial nephritis related to streptococcal pyrogenic exotoxin B.
Glomerulonephritis
Immunohistochemical and serological evidence for the role of streptococcal proteinase in acute post-streptococcal glomerulonephritis.
Glomerulonephritis
Is the nephritogenic antigen in post-streptococcal glomerulonephritis pyrogenic exotoxin B (SPE B) or GAPDH?
Glomerulonephritis
Role of streptococcal proteinase in acute post-streptococcal glomerulonephritis.
Glomerulonephritis
Streptococcal pyrogenic exotoxin B antibodies in a mouse model of glomerulonephritis.
Infections
An amino-terminal signal peptide of Vfr protein negatively influences RopB-dependent SpeB expression and attenuates virulence in Streptococcus pyogenes.
Infections
Antibody to streptococcal cysteine proteinase as a seromarker of group A Streptococcal (Streptococcus pyogenes) infections.
Infections
Application of the c3-binding motif of streptococcal pyrogenic exotoxin B to protect mice from invasive group a streptococcal infection.
Infections
Clinical and microbiological characteristics of severe group A streptococcus infections and streptococcal toxic shock syndrome.
Infections
Degradation of complement 3 by streptococcal pyrogenic exotoxin B inhibits complement activation and neutrophil opsonophagocytosis.
Infections
Determining antibody-binding site of streptococcal pyrogenic exotoxin B to protect mice from group a streptococcus infection.
Infections
Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production in the mouse model of group A streptococcal infection.
Infections
Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen.
Infections
Metal-mediated modulation of streptococcal cysteine protease activity and its biological implications.
Infections
Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection.
Infections
Streptococcal mitogenic exotoxin, SmeZ, is the most susceptible M1T1 streptococcal superantigen to degradation by the streptococcal cysteine protease, SpeB.
Infections
Streptococcal pyrogenic exotoxin B cleaves properdin and inhibits complement-mediated opsonophagocytosis.
Infections
Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage.
Infections
Structure of the mature streptococcal cysteine protease exotoxin mSpeB in its active dimeric form.
Infections
Synergistic effects of streptolysin S and streptococcal pyrogenic exotoxin B on the mouse model of group A streptococcal infection.
Lung Injury
Streptococcal cysteine protease augments lung injury induced by products of group A streptococci.
Melanoma
Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.
Nephritis, Interstitial
Acute poststreptococcal glomerulonephritis with acute interstitial nephritis related to streptococcal pyrogenic exotoxin B.
Pharyngitis
Detection of invasive protein profile of Streptococcus pyogenes M1 isolates from pharyngitis patients.
Pneumonia
Expression and characterization of group A Streptococcus extracellular cysteine protease recombinant mutant proteins and documentation of seroconversion during human invasive disease episodes.
Shock, Septic
Cysteine protease activity and histamine release from the human mast cell line HMC-1 stimulated by recombinant streptococcal pyrogenic exotoxin B/streptococcal cysteine protease.
Shock, Septic
Expression and characterization of group A Streptococcus extracellular cysteine protease recombinant mutant proteins and documentation of seroconversion during human invasive disease episodes.
Shock, Septic
Nucleotide sequence of the streptococcal pyrogenic exotoxin type B gene and relationship between the toxin and the streptococcal proteinase precursor.
Shock, Septic
The potential role of bacterial superantigens in the pathogenesis of Kawasaki syndrome.
Starvation
Life in protein-rich environments: the relA-independent response of Streptococcus pyogenes to amino acid starvation.
Starvation
Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletion.
Streptococcal Infections
Abrogation of streptococcal pyrogenic exotoxin B-mediated suppression of phagocytosis in U937 cells by Cordyceps sinensis mycelium via production of cytokines.
Streptococcal Infections
Application of the c3-binding motif of streptococcal pyrogenic exotoxin B to protect mice from invasive group a streptococcal infection.
Streptococcal Infections
Cysteine protease activity and histamine release from the human mast cell line HMC-1 stimulated by recombinant streptococcal pyrogenic exotoxin B/streptococcal cysteine protease.
Streptococcal Infections
Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production in the mouse model of group A streptococcal infection.
Streptococcal Infections
Identification and characterization of bicistronic speB and prsA gene expression in the group A Streptococcus.
Streptococcal Infections
Inverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection cases.
Streptococcal Infections
Role of streptococcal pyrogenic exotoxin B in the mouse model of group A streptococcal infection.
Streptococcal Infections
Studies of recombinant streptococcal pyrogenic exotoxin B/cysteine protease (rSPE B/SCP) in the skin of guinea pigs & the release of histamine from cultured mast cells & basophilic leukocytes.
Streptococcal Infections
Synergistic effects of streptolysin S and streptococcal pyrogenic exotoxin B on the mouse model of group A streptococcal infection.
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