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5-dimethylaminonaphthalene-1-sulfonyl-Phe-Arg-Phe(NO2)-Leu + H2O
?
pH 6.4, 37°C, 2 mM cysteine, 1 mM EDTA
-
-
?
Z-Phe-Arg-4-methylcoumarin-7-amide + H2O
Z-Phe-Arg + 7-amino-4-methylcoumarin
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-IEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-IEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
no hydrolysis at pH 6.0
-
?
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-D-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-L-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-D-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-L-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-LEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-LEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
no hydrolysis at pH 6.0
-
?
4-(4-dimethylaminophenylazo)benzoyl-LRGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-LRGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RIEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RIIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RIIEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
no hydrolysis at pH 6.0
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLVG-beta-(2-naphthyl)alanine-E-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVG-beta-(2-naphthyl)alanine-E + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLVGFD-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGFD + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLVGFE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGFE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLVGFL-alpha-aminoadipic acid-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGFL-alpha-aminoadipic acid + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLVGWE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGWE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
-
-
?
benzoyl-arginine ethyl ester + H2O
benzoyl-arginine + ethanol
-
-
-
?
benzoyl-DL-Arg-beta-naphthylamide + H2O
benzoyl-DL-Arg + beta-naphthylamine
-
-
-
?
benzoyl-DL-Arg-p-nitroanilide + H2O
benzoyl-DL-Arg + p-nitroaniline
-
-
-
?
benzoyl-DL-argininamide + H2O
benzoyl-DL-arginine + NH3
-
-
-
?
benzoyl-L-Arg-p-nitroanilide + H2O
benzoyl-L-Arg + p-nitroaniline
-
-
-
?
benzyloxycarbonyl-Arg-Arg-4-methylcoumarin 7-amide + H2O
benzyloxycarbonyl-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
?
benzyloxycarbonyl-Lys-4-nitrophenyl ester + H2O
benzyloxycarbonyl-Lys + 4-nitrophenol
-
-
-
?
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin-7-amide
benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
-
-
?
beta-lipotropin + H2O
hydrolyzed beta-lipotropin
-
-
-
?
carbobenzoxy-Arg-Arg-7-amido-4-methylcoumarin + H2O
carbobenzoxy-Arg-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
Collagen + H2O
Hydrolyzed collagen
-
-
-
?
histones + H2O
hydrolyzed histones
-
-
-
?
myristoylated alanine-rich C kinase substrate + H2O
?
-
i.e. MARCKS
-
-
?
myristoylated alanine-rich C kinase substrate + H2O
p40 + ?
-
i.e. MARCKS
-
?
N-benzyloxycarbonyl-L-lysine 4-nitrophenyl ester + H2O
?
-
-
-
-
?
N-benzyloxycarbonyl-L-lysine 4-nitrophenyl ester + H2O
N-benzyloxycarbonyl-L-lysine + 4-nitrophenol
-
-
-
-
?
trypsinogen + H2O
trypsin + peptide
-
-
-
-
?
Proteins + H2O
?
-
-
-
-
?
Proteins + H2O
?
-
turnover of intracellular proteins
-
-
?
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N-(trans-epoxysuccinyl)-L-leucine 4-guanidinobutylamide
addition of E-64 significantly decreases the activities of cathepsin B and caspase 3, and TUNEL-positive cells in heat-shocked in vitro maturated (IVM) bovine cumulus-oocyte complexes. Addition of inhibitor during in vitro maturation under heat shock conditions significantly improves both developmental competence and quality of the produced embryos
N-chloroacetyl-Gly-Leu-OH
-
N-chloroacetyl-Leu-Leu-OH
-
N-chloroacetyl-Leu-Leu-OMe
-
N-chloroacetyl-Lys-Leu-OH
-
N-chloroacetyl-Phe-Leu-OH
-
N-chloroacetyl-Phe-Met-OH
-
N-chloroacetyl-Ser-Leu-OH
-
2,2'-dipyridyl disulfide
-
-
4-hydroxy-2-nonenal
-
0.015 mM, 76% loss of activity, formation of Michael adducts with C29 of A chain and H150 of B chain
Benzyloxycarbonyl-Phe-Ala-CHN2
-
-
BzlNH-tES-Ile-Pro-OBzl
-
-
CAA0445
-
noncovalent-type, specific
E-64
-
inhibition of cathepsin B greatly improves the developmental competence of bovine oocytes and increases the number of high-quality embryos, overview
EtO-tES-Ile-Pro-OH
-
CA-030
L-3-carboxy-2,3-trans-epoxypropionyl-leucylamido-(4-guanidino)butane
-
E-64
MeO-Gly-Gly-Leu-NH-tES-Leu-Pro-OH
-
NS-134
N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucylamino-3-methylbutane
-
E64c
N-(L-3-trans-propylcarbamoyloxirane-2-carbonyl)-Ile-Pro
-
CA-074
N-ethylmaleimide
-
no inhibition at 1 mM
N-tosyl-lysyl chloromethylketone
-
-
oxalo-RAPTA
-
ruthenium(II)-arene compound
p-chloromercuribenzoate
-
-
peptidyl diazomethyl ketone derivatives
-
-
-
PrnNH-tES-Ile-Pro-OBzl
-
-
PrnNH-tES-Ile-Pro-OH
-
CA-074
PrnNH-tES-Ile-Pro-OMe
-
-
Proteinase inhibitors
-
from chicken´s egg white
-
RAPTA-BC
-
ruthenium(II)-arene compound
RAPTA-BI
-
ruthenium(II)-arene compound
RAPTA-C
-
i.e. carbo-RAPTA, ruthenium(II)-arene compound
RAPTA-H
-
ruthenium(II)-arene compound
-
RAPTA-Me+C
-
ruthenium(II)-arene compound
RAPTA-NH3
-
ruthenium(II)-arene compound
RAPTA-OH
-
ruthenium(II)-arene compound
RAPTA-pentaOH
-
binding structure from cyrstal structure of the inhibitor bound to cathepsin B, overview
RAPTA-T
-
ruthenium(II)-arene compound
RAPTA-TBMe
-
ruthenium(II)-arene compound
RAPTA-TBOH
-
ruthenium(II)-arene compound
trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2]
-
i.e. (PMRu52), a ruthenium(II) compound acting as a strong inhibitor of cathepsin B, crystal structure and binding structure analysis, overview
[(1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)Pd(1,3,5-triaza-7-phosphaadamantane)Cl]
-
-
[(benzyl(methyl)sulfane)Pd(1,3,5-triaza-7-phosphaadamantane)Cl]
-
-
[(N,N-dimethyl-1-phenylmethanamine)Pd(1,3,5-triaza-7-phosphaadamantane)Cl]
-
-
[Pd2((R)-3-isopropyl-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,1'-bis(diphenylphosphino)ferrocene)Cl2]
-
-
[Pd2((R)-3-isopropyl-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,2-bis(diphenylphosphino)ethane)Cl2]
-
-
[Pd2((S)-3-isopropyl-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,2-bis(diphenylphosphino)ethane)Cl2]
-
-
[Pd2(1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,1'-bis(diphenylphosphino)ferrocene)Cl2]
-
-
[Pd2(1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,2-bis(diphenylphosphino)ethane)Cl2]
-
-
chymostatin
-
-
chymostatin
-
80% inhibition at 6 microM
additional information
no inhibition with N-chloroacetyl-Gly-Gly-OH
-
additional information
-
no inhibition with N-chloroacetyl-Gly-Gly-OH
-
additional information
-
inhibition of cathepsin B by antitumor ruthenium(II)-arene compounds, mechanisms of binding/inhibition, overview
-
additional information
-
inhibitor screening and docking studies to cathepsin B, overview. Predicted bioactivities of inhibitor candidates and molecular mechanics
-
additional information
-
isolation and identification of a protein inhibitor of cathepsin B from Pseudomonas sp. strain PB01, phylogenetic distribution in Pseudomonas species, overview
-
additional information
-
correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles, that show in vitro activity as cytotoxic agents on A2780/S cells and also as cathepsin B inhibitors, synthesis and crystal structure of palladacycles, overview
-
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0.004
4-(4-dimethylaminophenylazo)benzoyl-IEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.0028 - 0.0036
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0035 - 0.0053
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0046 - 0.0078
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0037 - 0.0082
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0056
4-(4-dimethylaminophenylazo)benzoyl-LEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.006 - 0.0066
4-(4-dimethylaminophenylazo)benzoyl-LRGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0035
4-(4-dimethylaminophenylazo)benzoyl-R-LVGFE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 5.0
0.0037 - 0.0046
4-(4-dimethylaminophenylazo)benzoyl-RIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0055
4-(4-dimethylaminophenylazo)benzoyl-RIIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.0034 - 0.0049
4-(4-dimethylaminophenylazo)benzoyl-RLEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.001 - 0.0038
4-(4-dimethylaminophenylazo)benzoyl-RLVG-beta-(2-naphthyl)alanine-E-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0029 - 0.0059
4-(4-dimethylaminophenylazo)benzoyl-RLVGF-L-alpha-aminoadipic acid-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.003 - 0.0145
4-(4-dimethylaminophenylazo)benzoyl-RLVGFD-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.0022
4-(4-dimethylaminophenylazo)benzoyl-RLVGFE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0047 - 0.0078
4-(4-dimethylaminophenylazo)benzoyl-RLVGWE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
0.53
benzoyl-DL-Arg-beta-naphthylamide
-
-
0.114 - 0.125
benzyloxycarbonyl-Arg-Arg-4-methylcoumaryl-7-amide
-
-
0.0028
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 5.0
0.0036
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0035
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.0053
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0046
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0078
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 5.0
0.0037
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0082
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 5.0
0.006
4-(4-dimethylaminophenylazo)benzoyl-LRGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.0066
4-(4-dimethylaminophenylazo)benzoyl-LRGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0037
4-(4-dimethylaminophenylazo)benzoyl-RIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0046
4-(4-dimethylaminophenylazo)benzoyl-RIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.0034
4-(4-dimethylaminophenylazo)benzoyl-RLEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0049
4-(4-dimethylaminophenylazo)benzoyl-RLEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.001
4-(4-dimethylaminophenylazo)benzoyl-RLVG-beta-(2-naphthyl)alanine-E-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 5.0
0.0038
4-(4-dimethylaminophenylazo)benzoyl-RLVG-beta-(2-naphthyl)alanine-E-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0029
4-(4-dimethylaminophenylazo)benzoyl-RLVGF-L-alpha-aminoadipic acid-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0059
4-(4-dimethylaminophenylazo)benzoyl-RLVGF-L-alpha-aminoadipic acid-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.003
4-(4-dimethylaminophenylazo)benzoyl-RLVGFD-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
0.0145
4-(4-dimethylaminophenylazo)benzoyl-RLVGFD-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 4.5
0.0047
4-(4-dimethylaminophenylazo)benzoyl-RLVGWE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 5.0
0.0078
4-(4-dimethylaminophenylazo)benzoyl-RLVGWE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
-
pH 6.0
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0.046
BzlNH-tES-Ile-Pro-OBzl
Bos taurus
-
-
0.000029
BzlNH-tES-Ile-Pro-OH
Bos taurus
-
-
0.0153
EtO-tES-Gly-Pro-OH
Bos taurus
-
-
0.000023
EtO-tES-Ile-Ala-OH
Bos taurus
-
-
0.000024
EtO-tES-Ile-Ile-OH
Bos taurus
-
-
0.024
EtO-tES-Ile-OH
Bos taurus
-
-
0.00012
EtO-tES-Ile-Pro-OH
Bos taurus
-
-
0.00004
N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucylamino-3-methylbutane
Bos taurus
-
-
0.2
oxalo-RAPTA
Bos taurus
-
above, pH 6.0, 30°C
0.0091
PrnNH-tES-Ile-Pro-OBzl
Bos taurus
-
-
0.000038
PrnNH-tES-Ile-Pro-OH
Bos taurus
-
-
0.068
PrnNH-tES-Ile-Pro-OMe
Bos taurus
-
-
0.005
RAPTA-BC
Bos taurus
-
pH 6.0, 30°C
0.1
RAPTA-BI
Bos taurus
-
above, pH 6.0, 30°C
0.0025
RAPTA-C
Bos taurus
-
pH 6.0, 30°C
0.2
RAPTA-H
Bos taurus
-
above, pH 6.0, 30°C
-
0.0065
RAPTA-Me+C
Bos taurus
-
pH 6.0, 30°C
0.003
RAPTA-NH3
Bos taurus
-
pH 6.0, 30°C
0.0016
RAPTA-OH
Bos taurus
-
pH 6.0, 30°C
0.007
RAPTA-pentaOH
Bos taurus
-
pH 6.0, 30°C
0.0015
RAPTA-T
Bos taurus
-
pH 6.0, 30°C
0.082
RAPTA-TBMe
Bos taurus
-
pH 6.0, 30°C
0.0245
RAPTA-TBOH
Bos taurus
-
pH 6.0, 30°C
0.0055
trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2]
Bos taurus
-
pH 6.0, 30°C
0.0002
[(1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)Pd(1,3,5-triaza-7-phosphaadamantane)Cl]
Bos taurus
-
pH 6.0, 30°C
0.00015
[(benzyl(methyl)sulfane)Pd(1,3,5-triaza-7-phosphaadamantane)Cl]
Bos taurus
-
pH 6.0, 30°C
0.00007
[(N,N-dimethyl-1-phenylmethanamine)Pd(1,3,5-triaza-7-phosphaadamantane)Cl]
Bos taurus
-
pH 6.0, 30°C
0.000038
[Pd2((R)-3-isopropyl-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,1'-bis(diphenylphosphino)ferrocene)Cl2]
Bos taurus
-
pH 6.0, 30°C
0.0000095
[Pd2((R)-3-isopropyl-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,2-bis(diphenylphosphino)ethane)Cl2]
Bos taurus
-
pH 6.0, 30°C
0.000012
[Pd2((S)-3-isopropyl-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,2-bis(diphenylphosphino)ethane)Cl2]
Bos taurus
-
pH 6.0, 30°C
0.00003
[Pd2(1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,1'-bis(diphenylphosphino)ferrocene)Cl2]
Bos taurus
-
pH 6.0, 30°C
0.000023
[Pd2(1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one)2(m-1,2-bis(diphenylphosphino)ethane)Cl2]
Bos taurus
-
pH 6.0, 30°C
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Mycek, M.J.
Cathepsins
Methods Enzymol.
19
285-315
1970
Bos taurus, Rattus norvegicus
-
brenda
Spizz, G.; Blackshear, P.J.
Identification and characterization of cathepsin B as the cellular MARCKS cleaving enzyme
J. Biol. Chem.
272
23833-23842
1997
Bos taurus
brenda
Suhar, A.; Marks, N.
Purification and properties of brain cathepsin B. Evidence for cleavage of pituitary lipotropins
Eur. J. Biochem.
101
23-30
1979
Bos taurus
brenda
Etherington, D.J.
Bovine spleen cathepsin B1 and collagenolytic cathepsin. A comparative study of the properties of the two enzymes in the degradation of native collagen
Biochem. J.
153
199-209
1976
Bos taurus
brenda
Otto, K.; Riesenknig, H.
Improved purification of cathepsin B1 and cathepsin B2
Biochim. Biophys. Acta
379
462-475
1975
Bos taurus
brenda
Watanabe, H.; Green, G.D.J.; Shaw, E.
A comparison of the behavior of chymotrypsin and cathepsin B towards peptidyl diazomethyl ketones
Biochem. Biophys. Res. Commun.
89
1354-1360
1979
Bos taurus
brenda
Deval, C.; Bechet, D.; Obled, A.; Ferrara, M.
Purification and properties of different isoforms of bovine cathepsin B
Biochem. Cell Biol.
68
822-826
1990
Bos taurus
brenda
Stachowiak, K.; Tokmina, M.; Karpinska, A.; Sosnowska, R.; Wiczk, W.
Fluorogenic peptide substrates for carboxydipeptidase activity of cathepsin B
Acta Biochim. Pol.
51
81-92
2004
Bos taurus
brenda
Sentandreu, M.A.; Aubry, L.; Ouali, A.
Purification of bovine cathepsin B: Proteomic characterization of the different forms and production of specific antibodies
Biochem. Cell Biol.
81
317-326
2003
Bos taurus
brenda
Yamamoto, A.; Tomoo, K.; Matsugi, K.; Hara, T.; In, Y.; Murata, M.; Kitamura, K.; Ishida, T.
Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex
Biochim. Biophys. Acta
1597
244-251
2002
Bos taurus
brenda
Pillay, C.S.; Dennison, C.
Cathepsin B stability, but not activity, is affected in cysteine:cystine redox buffers
Biol. Chem.
383
1199-1204
2002
Bos taurus
brenda
Yamamoto, A.; Tomoo, K.; Hara, T.; Murata, M.; Kitamura, K.; Ishida, T.
Substrate specificity of bovine cathepsin B and its inhibition by CA074, based on crystal structure refinement of the complex
J. Biochem.
127
635-643
2000
Bos taurus
brenda
Crabb, J.W.; O'Neil, J.; Miyagi, M.; West, K.; Hoff, H.F.
Hydroxynonenal inactivates cathepsin B by forming Michael adducts with active site residues
Protein Sci.
11
831-840
2002
Bos taurus
brenda
Gilmore, B.F.; Harriott, P.; Walker, B.
The inactivation of bovine cathepsin B by novel N-chloro-acetyl-dipeptides: application of the Houghten tea bag methodology to inhibitor synthesis
Biochem. Biophys. Res. Commun.
333
1284-1288
2005
Bos taurus (P07688), Bos taurus
brenda
Ruzza, P.; Quintieri, L.; Osler, A.; Calderan, A.; Biondi, B.; Floreani, M.; Guiotto, A.; Borin, G.
Fluorescent, internally quenched, peptides for exploring the pH-dependent substrate specificity of cathepsin B
J. Pept. Sci.
12
455-461
2006
Bos taurus (P07688)
brenda
Watanabe, D.; Yamamoto, A.; Tomoo, K.; Matsumoto, K.; Murata, M.; Kitamura, K.; Ishida, T.
Quantitative evaluation of each catalytic subsite of cathepsin B for inhibitory activity based on inhibitory activity-binding mode relationship of epoxysuccinyl inhibitors by X-ray crystal structure analyses of complexes
J. Mol. Biol.
362
979-993
2006
Bos taurus
brenda
Zhou, Z.; Wang, Y.; Bryant, S.H.
Computational analysis of the cathepsin B inhibitors activities through LR-MMPBSA binding affinity calculation based on docked complex
J. Comput. Chem.
30
2165-2175
2009
Bos taurus
brenda
Casini, A.; Gabbiani, C.; Sorrentino, F.; Rigobello, M.P.; Bindoli, A.; Geldbach, T.J.; Marrone, A.; Re, N.; Hartinger, C.G.; Dyson, P.J.; Messori, L.
Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds
J. Med. Chem.
51
6773-6781
2008
Bos taurus
brenda
Hoang, l.e..T.V.; Kim, M.M.; Kim, S.K.
Effect of culture conditions on cathepsin B inhibitor production by a marine bacterium, Pseudomonas sp. strain PB01
J. Microbiol. Biotechnol.
18
1115-1120
2008
Bos taurus
brenda
Spencer, J.; Casini, A.; Zava, O.; Rathnam, R.P.; Velhanda, S.K.; Pfeffer, M.; Callear, S.K.; Hursthouse, M.B.; Dyson, P.J.
Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles
Dalton Trans.
2009
10731-10735
2009
Bos taurus, Homo sapiens
brenda
Mura, P.; Camalli, M.; Casini, A.; Gabbiani, C.; Messori, L.
Trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B
J. Inorg. Biochem.
104
111-117
2010
Bos taurus
brenda
Balboula, A.Z.; Yamanaka, K.; Sakatani, M.; Hegab, A.O.; Zaabel, S.M.; Takahashi, M.
Cathepsin B activity is related to the quality of bovine cumulus oocyte complexes and its inhibition can improve their developmental competence
Mol. Reprod. Dev.
77
439-448
2010
Bos taurus
brenda
Balboula, A.Z.; Yamanaka, K.; Sakatani, M.; Kawahara, M.; Hegab, A.O.; Zaabel, S.M.; Takahashi, M.
Cathepsin B activity has a crucial role in the developmental competence of bovine cumulus-oocyte complexes exposed to heat shock during in vitro maturation
Reproduction
146
407-417
2013
Bos taurus (P07688), Bos taurus
brenda