Reference on EC 3.4.21.B60 - transmembrane protease serine 2
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
David, A.; Parkinson, N.; Peacock, T.; Pairo-Castineira, E.; Khanna, T.; Cobat, A.; Tenesa, A.; Sancho-Shimizu, V.; Casanova, J.; Abel, L.; Barclay, W.; Baillie, J.; Sternberg, M.
A common TMPRSS2 variant has a protective effect against severe COVID-19
Curr. Res. Transl. Med.
70
103333
2022
Homo sapiens (O15393)
Baristaite, G.; Gurwitz, D.
Estradiol reduces ACE2 and TMPRSS2 mRNA levels in A549 human lung epithelial cells
Drug Dev. Res.
2022
1-6
2022
Homo sapiens (O15393)
Alzain, A.A.; Elbadwi, F.A.; Alsamani, F.O.
Discovery of novel TMPRSS2 inhibitors for COVID-19 using in silico fragment-based drug design, molecular docking, molecular dynamics, and quantum mechanics studies
Inform. Med. Unlocked
29
100870
2022
Homo sapiens
Schneider, M.A.; Richtmann, S.; Gruending, A.R.; Wrenger, S.; Welte, T.; Meister, M.; Kriegsmann, M.; Winter, H.; Muley, T.; Janciauskiene, S.
Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma
Int. J. Oncol.
60
39
2022
Homo sapiens (O15393)
Chen, Y.; Yang, W.; Chen, H.; Huang, L.; Gao, J.; Lin, C.; Wang, Y.; Yang, C.; Liu, Y.; Hou, M.; Tsai, C.; Chou, Y.; Huang, B.; Hung, C.; Hung, Y.; Wang, W.; Su, W.; Kumar, V.; Wu, Y.; Chao, S.; Chang, C.; Chen, J.; Chiang, Y.; Cho, D.; Jeng, L.; Tsai, C.
Tafenoquine and its derivatives as inhibitors for the severe acute respiratory syndrome coronavirus 2
J. Biol. Chem.
298
101658
2022
Homo sapiens
Kumar, V.; Dhanjal, J.; Bhargava, P.; Kaul, A.; Wang, J.; Zhang, H.; Kaul, S.; Wadhwa, R.; Sundar, D.
Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells
J. Biomol. Struct. Dyn.
40
1-13
2022
Homo sapiens (O15393)
Gyebi, G.A.; Adegunloye, A.P.; Ibrahim, I.M.; Ogunyemi, O.M.; Afolabi, S.O.; Ogunro, O.B.
Prevention of SARS-CoV-2 cell entry insight from in silico interaction of drug-like alkaloids with spike glycoprotein, human ACE2, and TMPRSS2
J. Biomol. Struct. Dyn.
40
2121-2145
2022
Homo sapiens (O15393)
Lee, J.H.; Lee, C.E.; Yoo, Y.; Shin, E.; An, J.; Park, S.Y.; Song, W.J.; Kwon, H.S.; Cho, Y.S.; Moon, H.B.; Kim, T.B.
Soluble ACE2 and TMPRSS2 levels in the serum of asthmatic patients
J. Korean Med. Sci.
37
e65
2022
Homo sapiens (O15393)
Salleh, M.Z.; Deris, Z.Z.
In silico molecular characterization of human TMPRSS2 protease polymorphic variants and associated SARS-CoV-2 susceptibility
Life
12
231
2022
Homo sapiens (O15393)
Guo, W.; Porter, L.M.; Crozier, T.W.; Coates, M.; Jha, A.; McKie, M.; Nathan, J.A.; Lehner, P.J.; Greenwood, E.J.; McCaughan, F.
Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures
Life Sci. Alliance
5
e202101116
2022
Homo sapiens (O15393)
Park, G.C.; Bang, S.Y.; Lee, H.W.; Choi, K.U.; Kim, J.M.; Shin, S.C.; Cheon, Y.I.; Sung, E.S.; Lee, M.; Lee, J.C.; Kim, H.S.; Lee, B.J.
ACE2 and TMPRSS2 immunolocalization and oral manifestations of COVID-19
Oral Dis.
2022
1-9
2022
Homo sapiens (O15393)
Vo, T.; Paudel, K.; Choudhary, I.; Patial, S.; Saini, Y.
Ozone exposure upregulates the expression of host susceptibility protein TMPRSS2 to SARS-CoV-2
Sci. Rep.
12
1357
2022
Mus musculus (Q9JIQ8)
Bai, X.; Buckle, A.M.; Vladar, E.K.; Janoff, E.N.; Khare, R.; Ordway, D.; Beckham, D.; Fornis, L.B.; Majluf-Cruz, A.; Fugit, R.V.; Freed, B.M.; Kim, S.; Sandhaus, R.A.; Chan, E.D.
Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19
Sci. Rep.
12
5207
2022
Homo sapiens (O15393)
Kapczynski, D.R.; Sweeney, R.; Spackman, E.; Pantin-Jackwood, M.; Suarez, D.L.
Development of an in vitro model for animal species susceptibility to SARS-CoV-2 replication based on expression of ACE2 and TMPRSS2 in avian cells
Virology
569
1-12
2022
Mesocricetus auratus, Capra hircus (A0A452FYA6), Homo sapiens (O15393), Felis catus (Q56H28)
Fujimoto, K.J.; Hobbs, D.C.F.; Umeda, M.; Nagata, A.; Yamaguchi, R.; Sato, Y.; Sato, A.; Ohmatsu, K.; Ooi, T.; Yanai, T.; Kimura, H.; Murata, T.
In silico analysis and synthesis of nafamostat derivatives and evaluation of their anti-SARS-CoV-2 activity
Viruses
14
389
2022
Homo sapiens (O15393)
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